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Professor Ron Trent

Professor of Medical Molecular Genetics
Medicine, Central Clinical School
Sydney Forensic Medicine and Science Network

C39 - Royal Prince Alfred Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9515 7514
F: +61 2 95505412
E:

Research interests

Ron is focussed on understanding the complex interactions that occur between genes and the environment and so lead to the important non-Mendelian genetic disorders that occur in the community.

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PhD and Masters' project opportunities

Molecular genetics of complex diseases

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Keywords

Motor neuron disease; Bioinformatics; Genetic diseases; Genetic processes

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Publications

2012 | 2011 | 2010 | 2009 | 2008 | 2007

2012

   
  • Ramos, E., Latourelle, J., Lee, J., Gillis, T., Mysore, J., Squitieri, F., Di Pardo, A., Di Donato, S., Hayden, M., Morrison, P., Nance, M., Ross, C., Margolis, R., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R., McCusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M., Hersch, S., Rosas, H., Lucente, D., Harrison, M., Zanko, A., Marder, K., Gusella, J., Lee, J., Alonso, I., Sequeiros, J., Myers, R., Macdonald, M. (2012), Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset. Human Genetics. 131(12), 1833-1840. [Abstract]
  • Poursoltan, P., Currey, N., Pangon, L., van Kralingen, C., Selinger, C., Mahar, A., Cooper, W., Kennedy, C., McCaughan, B., Trent, R., Kohonen-Corish, M. (2012), Loss of heterozygosity of the Mutated in Colorectal Cancer gene is not associated with promoter methylation in non-small cell lung cancer. Lung Cancer. 77(2), 272-276. [Abstract]
  • Pamphlett, R., Cheong, P., Trent, R., Yu, B. (2012), Transmission of C9orf72 hexanucleotide repeat expansions in sporadic amyotrophic lateral sclerosis: an Australian trio study. Neuroreport. 23(9), 556-559. [Abstract]
  • Lee, J., Gillis, T., Mysore, J., Ramos, E., Myers, R., Hayden, M., Morrison, P., Nance, M., Ross, C., Margolis, R., Squitieri, F., Griguoli, A., Di Donato, S., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R., McCusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M., Hersch, S., Rosas, H., Lucente, D., Harrison, M., Zanko, A., Abramson, R., Marder, K., Sequeiros, J., MacDonald, M., Gusella, J. (2012), Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. American Journal of Human Genetics. 90(3), 434-444. [Abstract]
  • Lee, J., Ramos, E., Lee, J., Gillis, T., Mysore, J., Hayden, M., Warby, S., Morrison, P., Nance, M., Ross, C., Margolis, R., Squitieri, F., Orobello, S., Di Donato, S., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R., McCusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M., Hersch, S., Rosas, H., Lucente, D., Harrison, M., Zanko, A., Abramson, R., Marder, K., Sequeiros, J., Paulsen, J., Landwehrmeyer, G., Myers, R., MacDonald, M., Gusella, J. (2012), CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology. 78(10), 690-695. [Abstract]

2011

   
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  • Watts, G., Sullivan, D., Poplawski, N., van Bockxmeer, F., Hamilton-Craig, I., Clifton, P., O'Brien, R., Bishop, W., George, P., Barter, P., Bates, T., Burnett, J., Coakley, J., Davidson, P., Emery, J., Martin, A., Farid, W., Freeman, L., Geelhoed, E., Juniper, A., Kidd, A., Kostner, K., Krass, I., Livingston, M., Maxwell, S., O'Leary, P., Owaimrin, A., Redgrave, T., Reid, N., Southwell, L., Suthers, G., Tonkin, A., Towler, S., Trent, R. (2011), Familial hypercholesterolaemia: A model of care for Australasia. Atherosclerosis. Supplements. 12(2), 221¿263. [Abstract]

2010

   
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  • Wollstein, A., Lao, O., Becker, C., Brauer, S., Trent, R., Nurnberg, P., Stoneking, M., Kayser, M. (2010), Demographic History of Oceania Inferred from Genome-wide Data. Current Biology. 20(22), 1983-1992. [Abstract]
  • Trent, R. (2010), Pathology practice and pharmacogenomics. Pharmacogenomics. 11(1), 105-111. [Abstract]
  • Luquin, N., Yu, B., Trent, R., Pamphlett, R. (2010), DHPLC can be used to detect low-level mutations in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis. 11(1-2), 76-82. [Abstract]
  • Yu, B., Trent, R. (2010), Genetics of Athletic Performance. In: Encyclopedia of Life Sciences. (pp.1-8).United Kingdom: John Wiley & Sons Ltd..

2009

   
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  • Luquin, N., Yu, B., Saunderson, R., Trent, R., Pamphlett, R. (2009), Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis. Neuromuscular Disorders. 19(10), 696-700. [Abstract]
  • Morahan, J., Yu, B., Trent, R., Pamphlett, R. (2009), A genome-wide analysis of brain DNA methylation identifies new candidate genes for sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis. 10(5-6), 418-429. [Abstract]
  • Trent, R., Yu, B. (2009), The future of genetic research in exercise science and sports medicine. Medicine and Sport Science. 54, 187-195. [Abstract]

2008

   
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  • Luquin, N., Yu, B., Trent, R., Morahan, J., Pamphlett, R. (2008), An analysis of the entire SOD1 gene in sporadic ALS. Neuromuscular disorders : NMD. 18(7), 545-52. [Abstract]
  • Saunderson, R., Yu, B., Trent, R., Pamphlett, R. (2008), A comparison of the lengths of androgen receptor triplet repeats in brain and blood in motor neuron diseases. Journal of the neurological sciences. 267(0), 125-8. [Abstract]
  • Le, H., Hinchcliffe, M., Yu, B., Trent, R. (2008), Computer-assisted reading of DNA sequences. Methods in Molecular Medicine. 141, 177-197. [Abstract]
  • Kayser, M., Lao, O., Saar, K., Brauer, S., Wang, X., Nurnberg, P., Trent, R., Stoneking, M. (2008), Genorne-wide analysis indicates more Asian than melanesian ancestry of polynesians. American Journal of Human Genetics. 82(1), 194-198. [Abstract]
  • Kayser, M., Choi, Y., van Oven, M., Mona, S., Brauer, S., Trent, R., Suarkia, D., Schiefenhovel, W., Stoneking, M. (2008), The impact of the Austronesian expansion: Evidence from mtDNA and Y chromosome diversity in the Admiralty Islands of Melanesia. Molecular Biology and Evolution. 25(7), 1362-1374. [Abstract]

2007

   
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  • Saunderson, R., Yu, B., Trent, R., Pamphlett, R. (2007), Low yield in screening patients with sporadic motor neuron disease for Kennedy disease. Internal medicine journal. 37(11), 772-774. [Abstract]
  • Morahan, J., Yu, B., Trent, R., Pamphlett, R. (2007), Genetic susceptibility to environmental toxicants in ALS. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 144B(7), 885-90. [Abstract]
  • Morahan, J., Yu, B., Trent, R., Pamphlett, R. (2007), A gene-environment study of the paraoxonase 1 gene and pesticides in amyotrophic lateral sclerosis. Neurotoxicology. 28, 532-40. [Abstract]
  • Myles, S., Hradetzky, E., Engelken, J., Lao, O., Nürnberg, P., Trent, R., Wang, X., Kayser, M., Stoneking, M. (2007), Identification of a candidate genetic variant for the high prevalence of type II diabetes in Polynesians. European journal of human genetics. 15(5), 584-589. [Abstract]
  • Saunderson, R., Yu, B., Trent, R., Pamphlett, R. (2007), Are enteroviral receptors different in sporadic motor neuron disease?. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 8(1), 26-30. [Abstract]
  • Morahan, J., Yu, B., Trent, R., Pamphlett, R. (2007), Are metallothionein genes silenced in ALS?. Toxicology letters. 168(1), 83-7. [Abstract]
  • Trent, R. (2007), NHMRC Human Genetics Advisory Committee. In: Human Biotechnology and Public Trust: Trends, Perceptions and Regulation. (pp.247-252).Australia: Centre for Law & Genetics, University of Tasmania.