KARAOKE Study – A randomized trial of krill oil for osteoarthritis of the knee

This study will determine whether treating people with krill oil improves knee pain and slows the progression of knee osteoarthritis over 6 months.

You may be eligible if you are:

  • over 40 years of age
  • have been diagnosed with osteoarthritis of the knee
  • have significant knee pain on most days
  • have swelling on knee MRI
  • able to travel to Royal North Shore Hospital to attend the study visits.

The project involves an initial screening assessment and knee MRI to determine your eligibility. The imaging services will be free of cost to you. You will also be asked to complete a set of questionnaires and perform simple function tests.

Eligible participants will be randomly assigned to one of two groups

  1. Receive 2g Krill Oil, or
  2. Placebo

All participants will be followed up over 6 months to examine whether krill oil affects the symptoms of knee osteoarthritis.

This study has been approved by the Northern Sydney Local Health District Human Research Ethics Committee – HREC/16/HAWKE/253.

Contact information
For more information about the study please contact Marita Cross by phone on 02 9463 1892 (Tues-Thurs) or email