Professor John Mitrofanis

Professor of Anatomy
Anatomy & Histology, School of Medical Sciences
Office of Medical Education (OME)

F13 - Anderson Stuart Building
The University of Sydney
NSW 2006 Australia

T: 93512500
F: 93512813

Research interests


Parkinson disease

International links

France. (Clinatec, CEA, Grenoble) Neuroprotection of dopaminergic cells Parkinson's disease.
United Kingdom. (UCL) Mechanisms of near infrared ligt in neuroprotection.


2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Moro, C., Massri, N., Torres, N., Ratel, D., De Jaeger, X., Chabrol, C., Perraut, F., Bourgerette, A., Berger, M., Purushothuman, S., Johnstone, D., Stone, J., Mitrofanis, J., Benabid, A. (2014), Photobiomodulation inside the brain: a novel method of applying near-infrared light intracranially and its impact on dopaminergic cell survival in MPTP-treated mice. Journal of Neurosurgery. 120(3), 670-683. [Abstract]
  • Johnstone, D., Massri, N., Moro, C., Spana, S., Wang, X., Torres, N., Chabrol, C., De Jaeger, X., Reinhart, F., Purushothuman, S., Benabid, A., Stone, J., Mitrofanis, J. (2014), Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism - an abscopal neuroprotective effect. Neuroscience. 274(C), 93-101. [Abstract]
  • Purushothuman, S., Johnstone, D., Nandasena, C., Mitrofanis, J., Stone, J. (2014), Photobiomodulation with near infrared light mitigates Alzheimer's disease-related pathology in cerebral cortex - evidence from two transgenic mouse models. Alzheimer's Research & Therapy. 6(1), 2. [Abstract]
  • Johnstone, D., Coleman, K., Moro, C., Torres, N., Eells, J., Baker5, G., Ashkan, K., Stone, J., Benabid, A., Mitrofanis, J. (2014), The potential of light therapy in Parkinson's disease. ChronoPhysiology and Therapy. 4, 1-14.


  • Purushothuman, S., Nandasena, C., Johnstone, D., Stone, J., Mitrofanis, J. (2013), The impact of near-infrared light on dopaminergic cell survival in a transgenic mouse model of parkinsonism. Brain Research. 1535C, 61-70. [Abstract]
  • Moro, C., Torres, N., El Massri, N., Ratel, D., Johnstone, D., Stone, J., Mitrofanis, J., Benabid, A. (2013), Photobiomodulation preserves behaviour and midbrain dopaminergic cells from MPTP toxicity: evidence from two mouse strains. BMC Neuroscience. 14(1), 40. [Abstract]
  • Stone, J., Johnstone, D., Mitrofanis, J. (2013), The helmet experiment in Parkinson's disease: an observation of the mechanism of neuroprotection by near infra-red light. Proceedings of the 9th WALT Congress.
  • Purushothuman, S., Nandasena, C., Peoples, C., El Massri, N., Johnstone, D., Mitrofanis, J., Stone, J. (2013), Saffron Pre-Treatment Offers Neuroprotection to Nigral and Retinal Dopaminergic Cells of MPTP-Treated mice. Journal of Parkinson's Disease. 3(1), 77-83. [Abstract]


  • Peoples, C., Spana, S., Ashkan, K., Benabid, A., Stone, J., Baker, G., Mitrofanis, J. (2012), Photobiomodulation enhances nigral dopaminergic cell survival in a chronic MPTP mouse model of Parkinson's disease. Parkinsonism & Related Disorders. 18(5), 469-476. [Abstract]
  • Peoples, C., Shaw, V., Stone, J., Jeffery, G., Baker, G., Mitrofanis, J. (2012), Survival of Dopaminergic Amacrine Cells after Near-Infrared Light Treatment in MPTP-Treated Mice. ISRN Neurology. 2012, 850150. [Abstract]
  • Shaw, V., Peoples, C., Spana, S., Ashkan, K., Benabid, A., Stone, J., Baker, G., Mitrofanis, J. (2012), Patterns of Cell Activity in the Subthalamic Region Associated with the Neuroprotective Action of Near-Infrared Light Treatment in MPTP-Treated Mice. Parkinson's disease. 2012, 296875. [Abstract]


  • Benabid, A., Mitrofanis, J., Chabardes, S., Seigneuret, E., Torres, N., Piallat, B., Benazzouz, A., Fraix, V., Krack, P., Pollak, P., Grand, S., Lebas, J. (2011), Subthalamic deep brain stimulation for Parkinson's disease. In: Youmans Neurological Surgery. (pp.944-962).United States: Saunders (Elsevier).


  • Shaw, V., Keay, K., Ashkan, K., Benabid, A., Mitrofanis, J. (2010), Dopaminergic cells in the periaqueductal grey matter of MPTP-treated monkeys and mice; patterns of survival and effect of deep brain stimulation and lesion of the subthalamic nucleus. Parkinsonism & related disorders. 16(5), 338-44. [Abstract]
  • Shaw, V., Spana, S., Ashkan, K., Benabid, A., Stone, J., Baker, G., Mitrofanis, J. (2010), Neuroprotection of midbrain dopaminergic cells in MPTP-treated mice after near-infrared light treatment. The Journal of Comparative Neurology. 518(1), 25-40. [Abstract]


  • Ma, J., Shaw, V., Mitrofanis, J. (2009), Does melatonin help save dopaminergic cells in MPTP-treated mice?. Parkinsonism & related disorders. 15(4), 307-314. [Abstract]
  • Benabid, A., Chabardes, S., Mitrofanis, J., Pollak, P. (2009), Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease. Lancet Neurology. 8(1), 67-81. [Abstract]


  • Reyes, S., Mitrofanis, J. (2008), Patterns of FOS Expression in the Spinal Cord and Periaqueductal Grey Matter of 6OHDA-Lesioned Rats. International Journal of Neuroscience. 118(8), 1053-1079. [Abstract]
  • Heise, C., Reyes, S., Mitrofanis, J. (2008), Sensory (nociceptive) stimulation evokes Fos expression in the subthalamus of hemiparkinsonian rats. Neurological research. 30(3), 277-284. [Abstract]
  • Luquin, N., Mitrofanis, J. (2008), Does the cerebral cortex exacerbate dopaminergic cell death in the substantia nigra of 6OHDA-lesioned rats?. Parkinsonism & related disorders. 14(0), 213-23. [Abstract]