2016 Publications

  • Ahmed, R. M., Caga, J., Devenney, E., Hsieh, S., Bartley, L., Highton-Williamson, E., Ramsey, E., Zoing, M., Halliday, G. M., Piguet, O., Hodges, J. R., and Kiernan, M. C. (2016) Cognition and eating behavior in amyotrophic lateral sclerosis: effect on survival, J Neurol 263, 1593-1603.
  • Ahmed, R. M., Devenney, E. M., Irish, M., Ittner, A., Naismith, S., Ittner, L. M., Rohrer, J. D., Halliday, G. M., Eisen, A., Hodges, J. R., and Kiernan, M. C. (2016) Neuronal network disintegration: common pathways linking neurodegenerative diseases, J Neurol Neurosurg Psychiatry 87, 1234-1241.
  • Ahmed, R. M., Irish, M., Henning, E., Dermody, N., Bartley, L., Kiernan, M. C., Piguet, O., Farooqi, S., and Hodges, J. R. (2016) Assessment of Eating Behavior Disturbance and Associated Neural Networks in Frontotemporal Dementia, JAMA Neurol 73, 282-290.
  • Ahmed, R. M., Irish, M., Piguet, O., Halliday, G. M., Ittner, L. M., Farooqi, S., Hodges, J. R., and Kiernan, M. C. (2016) Amyotrophic lateral sclerosis and frontotemporal dementia: distinct and overlapping changes in eating behaviour and metabolism, Lancet Neurol 15, 332-342.
  • Ahmed, R. M., Newcombe, R. E., Piper, A. J., Lewis, S. J., Yee, B. J., Kiernan, M. C., and Grunstein, R. R. (2016) Sleep disorders and respiratory function in amyotrophic lateral sclerosis, Sleep Med Rev 26, 33-42.
  • Albulym, O. M., Kennerson, M. L., Harms, M. B., Drew, A. P., Siddell, A. H., Auer-Grumbach, M., Pestronk, A., Connolly, A., Baloh, R. H., Zuchner, S., Reddel, S. W., and Nicholson, G. A. (2016) MORC2 mutations cause axonal Charcot-Marie-Tooth disease with pyramidal signs, Ann Neurol 79, 419-427.
  • Al-Chalabi, A., Hardiman, O., Kiernan, M. C., Chio, A., Rix-Brooks, B., and van den Berg, L. H. (2016) Amyotrophic lateral sclerosis: moving towards a new classification system, Lancet Neurol 15, 1182-1194.
  • Arnold, R., Pussell, B. A., Kiernan, M. C., and Krishnan, A. V. (2016) Comparative study to evaluate the ffects of peritoneal and hemodialysis on peripheral nerve function, Muscle Nerve 54, 58-64.
  • Bae, J. S., Ferguson, M., Tan, R., Mioshi, E., Simon, N., Burrell, J., Vucic, S., Hodges, J. R., Kiernan, M. C., and Hornberger, M. (2016) Dissociation of Structural and Functional Integrities of the Motor System in Amyotrophic Lateral Sclerosis and Behavioral-Variant Frontotemporal Dementia, J Clin Neurol 12, 209-217.
  • Barnett, M. H., Mathey, E., Kiernan, M. C., and Pollard, J. D. (2016) Axonal damage in central and peripheral nervous system inflammatory demyelinating diseases: common and divergent pathways of tissue damage, Curr Opin Neurol 29, 213-221.
  • Brewer, M. H., Chaudhry, R., Qi, J., Kidambi, A., Drew, A. P., Menezes, M. P., Ryan, M. M., Farrar, M. A., Mowat, D., Subramanian, G. M., Young, H. K., Zuchner, S., Reddel, S. W., Nicholson, G. A., and Kennerson, M. L. (2016) Whole Genome Sequencing Identifies a 78 kb Insertion from Chromosome 8 as the Cause of Charcot-Marie-Tooth Neuropathy CMTX3, PLoS Genet 12, e1006177.
  • Burrell, J. R., Halliday, G. M., Kril, J. J., Ittner, L. M., Gotz, J., Kiernan, M. C., and Hodges, J. R. (2016) The frontotemporal dementia-motor neuron disease continuum, Lancet 388, 919-931.
  • Caga, J., Turner, M. R., Hsieh, S., Ahmed, R. M., Devenney, E., Ramsey, E., Zoing, M. C., Mioshi, E., and Kiernan, M. C. (2016) Apathy is associated with poor prognosis in amyotrophic lateral sclerosis, Eur J Neurol 23, 891-897.
  • Chow, R. T., and Armati, P. J. (2016) Photobiomodulation: Implications for Anesthesia and Pain Relief, Photomed Laser Surg 34, 599-609.
  • De Silva, D., Hsieh, S., Caga, J., Leslie, F. V., Kiernan, M. C., Hodges, J. R., Mioshi, E., and Burrell, J. R. (2016) Motor function and behaviour across the ALS-FTD spectrum, Acta Neurol Scand 133, 367-372.
  • Devine, M. S., Ballard, E., O'Rourke, P., Kiernan, M. C., McCombe, P. A., and Henderson, R. D. (2016) Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis, Amyotroph Lateral Scler Frontotemporal Degener 17, 184-190.
  • Dharmadasa, T., Matamala, J. M., and Kiernan, M. C. (2016) Treatment approaches in motor neurone disease, Curr Opin Neurol 29, 581-591.
  • Dyer, W. B., Tan, J. C., Day, T., Kiers, L., Kiernan, M. C., Yiannikas, C., Reddel, S., Ng, K., Mondy, P., Dennington, P. M., Dean, M. M., Trist, H. M., Dos Remedios, C., Hogarth, P. M., Vucic, S., and Irving, D. O. (2016) Immunomodulation of inflammatory leukocyte markers during intravenous immunoglobulin treatment associated with clinical efficacy in chronic inflammatory demyelinating polyradiculoneuropathy, Brain Behav 6, e00516.
  • Farrar, M. A., Vucic, S., Nicholson, G., and Kiernan, M. C. (2016) Motor cortical dysfunction develops in spinocerebellar ataxia type 3, Clin Neurophysiol 127, 3418-3424.
  • Garg, N., Park, S. B., Vucic, S., Yiannikas, C., Spies, J., Howells, J., Huynh, W., Matamala, J. M., Krishnan, A. V., Pollard, J. D., Cornblath, D. R., Reilly, M. M., and Kiernan, M. C. (2016) Differentiating lower motor neuron syndromes, J Neurol Neurosurg Psychiatry.
  • Garg, N., Yiannikas, C., Hardy, T. A., Belaya, K., Cheung, J., Beeson, D., and Reddel, S. W. (2016) Late presentations of congenital myasthenic syndromes: How many do we miss?, Muscle Nerve 54, 721-727.
  • Garg, N., Yuki, N., Park, S. B., Barnett, M. H., and Kiernan, M. C. (2016) Acute bulbar, neck and limb weakness with monospecific anti-GT1a antibody: A rare localized subtype of Guillain-Barre syndrome, Muscle Nerve 53, 143-146.
  • Geevasinga, N., Loy, C. T., Menon, P., de Carvalho, M., Swash, M., Schrooten, M., Van Damme, P., Gawel, M., Sonoo, M., Higashihara, M., Noto, Y., Kuwabara, S., Kiernan, M. C., Macaskill, P., and Vucic, S. (2016) Awaji criteria improves the diagnostic sensitivity in amyotrophic lateral sclerosis: A systematic review using individual patient data, Clin Neurophysiol 127, 2684-2691.
  • Geevasinga, N., Menon, P., Ng, K., Van Den Bos, M., Byth, K., Kiernan, M. C., and Vucic, S. (2016) Riluzole exerts transient modulating effects on cortical and axonal hyperexcitability in ALS, Amyotroph Lateral Scler Frontotemporal Degener 17, 580-588.
  • Geevasinga, N., Menon, P., Ozdinler, P. H., Kiernan, M. C., and Vucic, S. (2016) Pathophysiological and diagnostic implications of cortical dysfunction in ALS, Nat Rev Neurol 12, 651-661.
  • Geevasinga, N., Menon, P., Scherman, D. B., Simon, N., Yiannikas, C., Henderson, R. D., Kiernan, M. C., and Vucic, S. (2016) Diagnostic criteria in amyotrophic lateral sclerosis: A multicenter prospective study, Neurology 87, 684-690.
  • Halliday, G. M., Kiernan, M. C., Kril, J. J., Mito, R., Masuda-Suzukake, M., Hasegawa, M., McCann, H., Bartley, L., Dobson-Stone, C., Kwok, J. B., Hornberger, M., Hodges, J. R., and Tan, R. H. (2016) TDP-43 in the hypoglossal nucleus identifies amyotrophic lateral sclerosis in behavioral variant frontotemporal dementia, J Neurol Sci 366, 197-201.
  • Hardy, T. A., Lee, A. W., Yiannikas, C., Chen, C. S., and Reddel, S. W. (2016) Extensive Postradiation Ocular and Diffuse Cranial Neuromyotonia Mimicking Myasthenia Gravis, Neurologist 21, 79-82.
  • Hardy, T. A., Reddel, S. W., Barnett, M. H., Palace, J., Lucchinetti, C. F., and Weinshenker, B. G. (2016) Atypical inflammatory demyelinating syndromes of the CNS, Lancet Neurol 15, 967-981.
  • Hornberger, M., and Kiernan, M. C. (2016) Emergence of an imaging biomarker for amyotrophic lateral sclerosis: is the end point near?, J Neurol Neurosurg Psychiatry 87, 569.
  • Hsieh, S., Caga, J., Leslie, F. V., Shibata, M., Daveson, N., Foxe, D., Ramsey, E., Lillo, P., Ahmed, R. M., Devenney, E., Burrell, J. R., Hodges, J. R., Kiernan, M. C., and Mioshi, E. (2016) Cognitive and Behavioral Symptoms in ALSFTD: Detection, Differentiation, and Progression, J Geriatr Psychiatry Neurol 29, 3-10.
  • Hsieh, S., Irish, M., Foxe, D., Caga, J., Devenney, E., Ahmed, R., Hodges, J. R., Piguet, O., and Kiernan, M. C. (2016) My memories are important to me: Changes in autobiographical memory in amyotrophic lateral sclerosis, Neuropsychology 30, 920-930.
  • Hsieh, S., Leyton, C. E., Caga, J., Flanagan, E., Kaizik, C., O'Connor, C. M., Kiernan, M. C., Hodges, J. R., Piguet, O., and Mioshi, E. (2016) The Evolution of Caregiver Burden in Frontotemporal Dementia with and without Amyotrophic Lateral Sclerosis, J Alzheimers Dis 49, 875-885.
  • Huynh, W., Pickering, H., Howells, J., Murray, J., Cormack, C., Lin, C. S., Vucic, S., Kiernan, M. C., and Krishnan, A. V. (2016) Effect of fampridine on axonal excitability in multiple sclerosis, Clin Neurophysiol 127, 2636-2642.
  • Huynh, W., Simon, N. G., Grosskreutz, J., Turner, M. R., Vucic, S., and Kiernan, M. C. (2016) Assessment of the upper motor neuron in amyotrophic lateral sclerosis, Clin Neurophysiol 127, 2643-2660.
  • Huynh, W., Vucic, S., Krishnan, A. V., Lin, C. S., and Kiernan, M. C. (2016) Exploring the Evolution of Cortical Excitability Following Acute Stroke, Neurorehabil Neural Repair 30, 244-257.
  • Kamminga, J., Leslie, F. V., Hsieh, S., Caga, J., Mioshi, E., Hornberger, M., Ballard, K. J., Kiernan, M. C., Hodges, J. R., and Burrell, J. R. (2016) Syntactic comprehension deficits across the FTD-ALS continuum, Neurobiol Aging 41, 11-18.
  • Kiernan, M. C. (2016) The Babinski sign, Pract Neurol 16, 419-420.
  • Kiernan, M. C. (2016) 35,000 Days on Earth, J Neurol Neurosurg Psychiatry 87, 1-2.
  • Kwai, N. C., Arnold, R., Poynten, A. M., Howells, J., Kiernan, M. C., Lin, C. S., and Krishnan, A. V. (2016) In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes, Clin Neurophysiol 127, 1700-1706.
  • Menezes, M. P., Farrar, M. A., Webster, R., Antony, J., O'Brien, K., Ouvrier, R., Kiernan, M. C., Burns, J., and Vucic, S. (2016) Pathophysiology of motor dysfunction in a childhood motor neuron disease caused by mutations in the riboflavin transporter, Clin Neurophysiol 127, 911-918.
  • Menon, P., Geevasinga, N., Yiannikas, C., Kiernan, M. C., and Vucic, S. (2016) Cortical contributions to the flail leg syndrome: Pathophysiological insights, Amyotroph Lateral Scler Frontotemporal Degener 17, 389-396.
  • Murray, L., Butow, P. N., White, K., Kiernan, M. C., D'Abrew, N., and Herz, H. (2016) Advance care planning in motor neuron disease: A qualitative study of caregiver perspectives, Palliat Med 30, 471-478.
  • Noto, Y., Shibuya, K., Vucic, S., and Kiernan, M. C. (2016) Novel therapies in development that inhibit motor neuron hyperexcitability in amyotrophic lateral sclerosis, Expert Rev Neurother 16, 1147-1154.
  • O'Grady, G. L., Best, H. A., Sztal, T. E., Schartner, V., Sanjuan-Vazquez, M., Donkervoort, S., Abath Neto, O., Sutton, R. B., Ilkovski, B., Romero, N. B., Stojkovic, T., Dastgir, J., Waddell, L. B., Boland, A., Hu, Y., Williams, C., Ruparelia, A. A., Maisonobe, T., Peduto, A. J., Reddel, S. W., Lek, M., Tukiainen, T., Cummings, B. B., Joshi, H., Nectoux, J., Brammah, S., Deleuze, J. F., Ing, V. O., Ramm, G., Ardicli, D., Nowak, K. J., Talim, B., Topaloglu, H., Laing, N. G., North, K. N., MacArthur, D. G., Friant, S., Clarke, N. F., Bryson-Richardson, R. J., Bonnemann, C. G., Laporte, J., and Cooper, S. T. (2016) Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization, Am J Hum Genet 99, 1086-1105.
  • Pamphlett, R., and Kum Jew, S. (2016) Age-Related Uptake of Heavy Metals in Human Spinal Interneurons, PLoS One 11, e0162260.
  • Pamphlett, R., and Kum Jew, S. (2016) Locus ceruleus neurons in people with autism contain no histochemically-detectable mercury, Biometals 29, 171-175.
  • Ramanathan, S., Prelog, K., Barnes, E. H., Tantsis, E. M., Reddel, S. W., Henderson, A. P., Vucic, S., Gorman, M. P., Benson, L. A., Alper, G., Riney, C. J., Barnett, M., Parratt, J. D., Hardy, T. A., Leventer, R. J., Merheb, V., Nosadini, M., Fung, V. S., Brilot, F., and Dale, R. C. (2016) Radiological differentiation of optic neuritis with myelin oligodendrocyte glycoprotein antibodies, aquaporin-4 antibodies, and multiple sclerosis, Mult Scler 22, 470-482.
  • Rigney, L. A., El-Haddad, C., Cappelen-Smith, C., Pamphlett, R., Gotis-Graham, I., and Cordato, D. J. (2016) Rhabdomyolysis as a late complication of bariatric surgery, J Neurol Sci 364, 102-104.
  • Rzhepetskyy, Y., Lazniewska, J., Blesneac, I., Pamphlett, R., and Weiss, N. (2016) CACNA1H missense mutations associated with amyotrophic lateral sclerosis alter Cav3.2 T-type calcium channel activity and reticular thalamic neuron firing, Channels (Austin) 10, 466-477.
  • Shahrizaila, N., Sobue, G., Kuwabara, S., Kim, S. H., Birks, C., Fan, D. S., Bae, J. S., Hu, C. J., Gourie-Devi, M., Noto, Y., Shibuya, K., Goh, K. J., Kaji, R., Tsai, C. P., Cui, L., Talman, P., Henderson, R. D., Vucic, S., and Kiernan, M. C. (2016) Amyotrophic lateral sclerosis and motor neuron syndromes in Asia, J Neurol Neurosurg Psychiatry 87, 821-830.
  • Shibuya, K., Park, S. B., Geevasinga, N., Huynh, W., Simon, N. G., Menon, P., Howells, J., Vucic, S., and Kiernan, M. C. (2016) Threshold tracking transcranial magnetic stimulation: Effects of age and gender on motor cortical function, Clin Neurophysiol 127, 2355-2361.
  • Shibuya, K., Park, S. B., Geevasinga, N., Menon, P., Howells, J., Simon, N. G., Huynh, W., Noto, Y., Gotz, J., Kril, J. J., Ittner, L. M., Hodges, J., Halliday, G., Vucic, S., and Kiernan, M. C. (2016) Motor cortical function determines prognosis in sporadic ALS, Neurology 87, 513-520.
  • Simon, N. G., and Kiernan, M. C. (2016) Diaphragm ultrasound in amyotrophic lateral sclerosis and other neuromuscular disorders, Clin Neurophysiol 127, 28-30.
  • Simon, N. G., Lagopoulos, J., Gallagher, T., Kliot, M., and Kiernan, M. C. (2016) Peripheral nerve diffusion tensor imaging is reliable and reproducible, J Magn Reson Imaging 43, 962-969.
  • Stoll, M., Teoh, H., Lee, J., Reddel, S., Zhu, Y., Buckley, M., Sampaio, H., Roscioli, T., Farrar, M., and Nicholson, G. (2016) Novel motor phenotypes in patients with VRK1 mutations without pontocerebellar hypoplasia, Neurology 87, 65-70.
  • Tan, R. H., Kril, J. J., McGinley, C., Hassani, M., Masuda-Suzukake, M., Hasegawa, M., Mito, R., Kiernan, M. C., and Halliday, G. M. (2016) Cerebellar neuronal loss in amyotrophic lateral sclerosis cases with ATXN2 intermediate repeat expansions, Ann Neurol 79, 295-305.
  • Timmins, H. C., Saw, W., Cheah, B. C., Lin, C. S., Vucic, S., Ahmed, R. M., Kiernan, M. C., and Park, S. B. (2016) Cardiometabolic health and risk of amyotrophic lateral sclerosis, Muscle Nerve.
  • van Rheenen, W., and Shatunov, A., and Dekker, A. M., and McLaughlin, R. L., and Diekstra, F. P., and Pulit, S. L., and van der Spek, R. A., and Vosa, U., and de Jong, S., and Robinson, M. R., and Yang, J., and Fogh, I., and van Doormaal, P. T., and Tazelaar, G. H., and Koppers, M., and Blokhuis, A. M., and Sproviero, W., and Jones, A. R., and Kenna, K. P., and van Eijk, K. R., and Harschnitz, O., and Schellevis, R. D., and Brands, W. J., and Medic, J., and Menelaou, A., and Vajda, A., and Ticozzi, N., and Lin, K., and Rogelj, B., and Vrabec, K., and Ravnik-Glavac, M., and Koritnik, B., and Zidar, J., and Leonardis, L., and Groselj, L. D., and Millecamps, S., and Salachas, F., and Meininger, V., and de Carvalho, M., and Pinto, S., and Mora, J. S., and Rojas-Garcia, R., and Polak, M., and Chandran, S., and Colville, S., and Swingler, R., and Morrison, K. E., and Shaw, P. J., and Hardy, J., and Orrell, R. W., and Pittman, A., and Sidle, K., and Fratta, P., and Malaspina, A., and Topp, S., and Petri, S., and Abdulla, S., and Drepper, C., and Sendtner, M., and Meyer, T., and Ophoff, R. A., and Staats, K. A., and Wiedau-Pazos, M., and Lomen-Hoerth, C., and Van Deerlin, V. M., and Trojanowski, J. Q., and Elman, L., and McCluskey, L., and Basak, A. N., and Tunca, C., and Hamzeiy, H., and Parman, Y., and Meitinger, T., and Lichtner, P., and Radivojkov-Blagojevic, M., and Andres, C. R., and Maurel, C., and Bensimon, G., and Landwehrmeyer, B., and Brice, A., and Payan, C. A., and Saker-Delye, S., and Durr, A., and Wood, N. W., and Tittmann, L., and Lieb, W., and Franke, A., and Rietschel, M., and Cichon, S., and Nothen, M. M., and Amouyel, P., and Tzourio, C., and Dartigues, J. F., and Uitterlinden, A. G., and Rivadeneira, F., and Estrada, K., and Hofman, A., and Curtis, C., and Blauw, H. M., and van der Kooi, A. J., and de Visser, M., and Goris, A., and Weber, M., and Shaw, C. E., and Smith, B. N., and Pansarasa, O., and Cereda, C., and Del Bo, R., and Comi, G. P., and D'Alfonso, S., and Bertolin, C., and Soraru, G., and Mazzini, L., and Pensato, V., and Gellera, C., and Tiloca, C., and Ratti, A., and Calvo, A., and Moglia, C., and Brunetti, M., and Arcuti, S., and Capozzo, R., and Zecca, C., and Lunetta, C., and Penco, S., and Riva, N., and Padovani, A., and Filosto, M., and Muller, B., and Stuit, R. J., and Registry, P., and Group, S., and Registry, S., and Consortium, F. S., and Consortium, S., and Group, N. S., and Blair, I., and Zhang, K., and McCann, E. P., and Fifita, J. A., and Nicholson, G. A., and Rowe, D. B., and Pamphlett, R., and Kiernan, M. C., et al and Grosskreutz, J., and Witte, O. W., and Ringer, T., and Prell, T., and Stubendorff, B., and Kurth, I., and Hubner, C. A., and Leigh, P. N., and Casale, F., and Chio, A., and Beghi, E., and Pupillo, E., and Tortelli, R., and Logroscino, G., and Powell, J., and Ludolph, A. C., and Weishaupt, J. H., and Robberecht, W., and Van Damme, P., and Franke, L., and Pers, T. H., and Brown, R. H., and Glass, J. D., and Landers, J. E., and Hardiman, O., and Andersen, P. M., and Corcia, P., and Vourc'h, P., and Silani, V., and Wray, N. R., and Visscher, P. M., and de Bakker, P. I., and van Es, M. A., and Pasterkamp, R. J., and Lewis, C. M., and Breen, G., and Al-Chalabi, A., and van den Berg, L. H., and Veldink, J. H. (2016) Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis, Nat Genet 48, 1043-1048.