The NSW Brain Tissue Resource Centre is a research facility for the collection, characterisation, storage and distribution of human brain and spinal cord tissue for research. The tissues provided to the neuroscientific research community include investigations on understanding the framework, composition and functioning of the human brain and the nature of neurological and neurodegenerative diseases.

Many neurologic and psychiatric conditions affect only humans, such as schizophrenia and alcohol related brain disorders. There are few animal models available that can accurately replicate these conditions particularly in the case of schizophrenia. Along with neurodegenerative diseases such as Alzheimer’s disease these health issues impact upon society, including economic burden for both an individual and community.

Brains from people with these illnesses are essential for research devoted to finding treatments and cures. Progress can be made towards finding the cause of neurological and psychiatric conditions if researchers can compare brains from those affected with brains from those who were not affected by such conditions. Normal brain tissue can also be used to study ageing of the human brain. Normal brain tissue is known as 'control' tissue and is extremely important to identify physiological and chemical differences between healthy tissue and 'abnormal' changes.