%0 Journal Article %~ PubMed %A Turner, Paul J %A Wong, Melanie %A Varese, Nirupama %A Rolland, Jennifer M %A O'Hehir, Robyn E %A Campbell, Dianne E %T Tolerance to wheat in whole-grain cereal biscuit in wheat-allergic children. %B Journal of Allergy and Clinical Immunology %D 2013 %C United States %I Mosby, Inc. %V 131 %N 3 %P 920-923 %@ 1097-6825 %X %Z FOR Codes: 1114 1107 %0 Conference Proceedings %A Koulias, Marianna %A Leahy, Gregory %A Scott, Karen %A Phelps, Megan %A Campbell, Dianne %T "Wherever, whenever" learning in Medicine: Evaluation of an interactive mobile case-based project %B Future Challenges/ Sustainable Futures %D 2012 %C Wellington, NZ 25-28 Nov 2012 %I Massey University %V %N %P %@ 9780173229894 %E Brown, M %E Harnett, M %E Stewart, T %X %Z FOR Codes: 130209 %0 Journal Article %~ PubMed %A Tan, John %A Campbell, Dianne %A Mehr, Sam %T Food protein-induced enterocolitis syndrome in an exclusively breast-fed infant-an uncommon entity. %B Journal of Allergy and Clinical Immunology %D 2012 %C United States %I Mosby, Inc. %V 129 %N 3 %P 873 %@ 1097-6825 %X %Z FOR Codes: 1107 1114 %0 Journal Article %~ PubMed %A Turner, Paul J %A Kakakios, Alyson %A Wong, Li-Chuen %A Wong, Melanie %A Campbell, Dianne E %T Intravenous Immunoglobulin to Treat Severe Atopic Dermatitis in Children: A Case Series. %B Pediatric Dermatology %D 2012 %C United States %I Wiley-Blackwell Publishing, Inc. %V 29 %N 2 %P 177-181 %@ 1525-1470 %X ??? Severe cases of atopic dermatitis (AD) may require systemic immunosuppression to achieve disease control. Unfortunately, some cases continue to be refractory to management or develop unacceptable adverse effects. There are limited reports of the use of intravenous immunoglobulin (IVIg) in the treatment of severe AD, but results are inconsistent. In a retrospective study, we report 10 children with severe AD refractory to systemic immunosuppression and maximal topical therapy who were treated using IVIg. The children received monthly IVIg for an average of 24???months. This resulted in a significant improvement in symptoms, with fewer infection-related exacerbations and hospitalizations, allowing systemic immunosuppression to be tapered. The effect was associated with a significant decrease in serum immunoglobulin E and was sustained after cessation of IVIg in 50% of cases. No significant side effects attributable to the IVIg infusions were noted. In this cohort of children with severe AD and recurrent cutaneous infections, IVIg provided an effective treatment with minimal side effects and significant benefits in school attendance and quality of life. %Z FOR Codes: 1114 1107 %0 Journal Article %~ PubMed %A Campbell, Dianne E %T Role of food allergy in childhood atopic dermatitis. %B Journal of Paediatrics and Child Health %D 2012 %C United Kingdom %I Wiley-Blackwell Publishing Ltd. %V 48 %N 12 %P 1058-1064 %@ 1034-4810 %X The interplay between atopic dermatitis (AD) and food allergy is complex and subject to significant misconceptions both by the general public and the medical community. Childhood AD is a very prevalent disorder. In its moderate and severe forms, AD is a challenging disorder to manage from the perspective of the child, parent and treating doctor. As AD is one of the disease manifestations of atopy, it is unsurprising that many children with AD also have a coexisting IgE-mediated food allergy. It is a common misconception that food allergy is causal in the setting of AD. However, in a proportion of sufferers, food allergy does play a role in triggering or exacerbating pre-existing AD by immune-mediated mechanisms and potentially by non-immune mechanisms. It is, therefore, important to differentiate causality, co-existent disease and disease modifiers in this context. This paper seeks to clarify the role of food allergy in childhood AD, and to outline a rational framework for the diagnosis and approach to food allergy in the context of the management of a child with problematic AD. %Z FOR Codes: 1114 1107 %0 Journal Article %~ PubMed %A Turner, Paul J %A Kemp, Andrew S %A Campbell, Dianne E %T Advisory food labels: consumers with allergies need more than "traces" of information. %B BMJ %D 2011 %C United Kingdom %I B M J Group %V 343 %N %P d6180 %@ 1468-5833 %X %Z FOR Codes: 1114 1107 %0 Journal Article %~ PubMed %A Murphy, Andrew %A Campbell, Dianne E %A Baines, David %A Mehr, Sam %T Allergic Reactions to Propofol in Egg-Allergic Children. %B Anesthesia and analgesia %D 2011 %C United States %I Lippincott Williams & Wilkins %V 113 %N 1 %P 140-4 %@ 0003-2999 %X Egg and/or soy allergy are often cited as contraindications to propofol administration. Our aim was to determine whether children with an immunoglobulin (Ig)E-mediated egg and/or soy allergy had an allergic reaction after propofol use. %Z FOR Codes: 1107 1114 %0 Journal Article %~ PubMed %A Turner, Paul J %A Gray, Paul E A %A Wong, Melanie %A Varese, Nirupama %A Rolland, Jennifer M %A O'Hehir, Robyn %A Campbell, Dianne E %T Anaphylaxis to apple and orange seed. %B The Journal of allergy and clinical immunology %D 2011 %C United States %I Mosby, Inc. %V 128 %N 6 %P 1363-5 %@ 1097-6825 %X %Z FOR Codes: 1114 1107 %0 Journal Article %~ PubMed %A Campbell, Dianne E %T How to write good multiple-choice questions. %B Journal of paediatrics and child health %D 2011 %C United Kingdom, Australia %I Wiley-Blackwell Publishing Ltd. %V 47 %N 6 %P 322-5 %@ 1034-4810 %X Medical practitioners are frequently called upon to write multiple-choice questions for high stakes examinations, such as final year medical student assessments and specialist college accreditation examinations. The fairness and validity of these examinations depends principally on the generation of high-quality questions, which adequately sample the curriculum. The most common format for multiple-choice examinations are single best answer and extended matching type questions. This paper provides a simple guideline that will assist with the production of high-quality multiple-choice papers in these formats. %Z FOR Codes: 111403 %0 Journal Article %~ PubMed %A Ng, Ian E %A Turner, Paul J %A Kemp, Andrew S %A Campbell, Dianne E %T Parental perceptions and dietary adherence in children with seafood allergy. %B Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology %D 2011 %C United States %I Wiley-Blackwell Publishing Ltd. %V 22 %N 7 %P 720-8 %@ 1399-3038 %X Allergy to seafood (fish, mollusc and crustacean) is increasing and is now a leading cause of food anaphylaxis, but there is only limited data on the impact of seafood allergy on affected children and their families. %Z FOR Codes: 1114 1107 %0 Journal Article %~ PubMed %A Turner, Paul %A Ng, Ian %A Kemp, Andrew %A Campbell, Dianne %T Seafood allergy in children: a descriptive study. %B Annals of Allergy, Asthma, & Immunology %D 2011 %C United States %I Elsevier Inc. %V 106 %N 6 %P 494-501 %@ 1534-4436 %X Food allergy and seafood (fish, mollusk, and crustacean) consumption have increased considerably over the past 40 years. Seafood allergy is now a leading cause of anaphylaxis in both the United States and Australia. However, there is only limited published data describing the clinical presentation and management of seafood allergy. %Z FOR Codes: 1107 1114 %0 Journal Article %~ PubMed %A Thomson, Natasha M %A Campbell, Dianne E %A O'Leary, Fenton M %T Teaching medical students to resuscitate children: An innovative two-part programme. %B Emergency Medicine Australasia %D 2011 %C Australia %I Wiley-Blackwell Publishing Asia %V 23 %N 6 %P 741-747 %@ 1742-6723 %X Objective: The objective of the present study was to design and evaluate a novel, ''blended learning'' approach to the teaching of paediatric resuscitation to medical students. Methods: Participants were recruited from the Graduate Medical Program at the University of Sydney. The course incorporated an initial e-learning module and a subsequent practical component. The e-learning module taught basic and advanced life support. Students then attended a 90???min practical session, which focussed on team work and the psychomotor components of resuscitation. Improvement in knowledge was measured by a multiple choice question (MCQ) test. The MCQ was completed prior to beginning the whole course, after completion of the e-learning module and again at follow up 8???months later. Students also completed an evaluation survey. Results: Twenty-one students participated. There was a significant objective increase in knowledge from pre-course to post e-learning scores, median scores (interquartile range) from 12/23 (10.5 to 13.5) to 21/23 (20 to 22.5), P < 0.001. This significant increase in knowledge was still apparent at follow up 8???months later. Median MCQ score at follow up was 17/23 (14 to 18.5), P < 0.002. Students self-rated significant improvements in their knowledge, confidence and ability to perform basic and advanced life support for the whole course and between individual components (P < 0.001). Conclusions: A novel paediatric resuscitation course for medical students was developed and evaluated. This demonstrated significant objective improvements in student knowledge throughout the course, at course completion and at 8???month follow up. There were also significant subjective improvements in knowledge, confidence and ability to perform paediatric resuscitation. %Z FOR Codes: 1114 1103 %0 Journal Article %~ PubMed %A Campbell, Dianne %T To be wanted or needed--is that the question? %B Journal of Paediatrics and Child Health %D 2011 %C United Kingdom, Australia %I Wiley-Blackwell Publishing Ltd. %V 47 %N 3 %P 72 %@ 1034-4810 %X %Z FOR Codes: 1114 %0 Journal Article %A Chadban, Steven %A Howell, M %A Twigg, Stephen %A Thomas, M %A Cass, Alan %A Campbell, Dianne %A Tong, Alan %A Mangos, G %A Stack, A %A MacIsaac, R %A Girgis, Seham %A Colagiuri, Ruth %A Colagiuri, Stephen %A Craig, Jonathan %T Assessment of kidney function in type 2 diabetes %B Nephrology %D 2010 %C Australia %I Wiley-Blackwell Publishing Asia %V 15 %N Supp 1 %P S146-S161 %@ 1440-1797 %X %Z FOR Codes: 110312 %0 Journal Article %~ PubMed %A Chadban, S %A Howell, M %A Twigg, S %A Thomas, M %A Jerums, G %A Cass, A %A Campbell, D %A Nicholls, K %A Tong, A %A Mangos, G %A Stack, A %A MacIsaac, R J %A Girgis, S %A Colagiuri, R %A Colagiuri, S %A Craig, J %A , CARI %T The CARI guidelines. Cost-effectiveness and socioeconomic implications of prevention and management of chronic kidney disease in type 2 diabetes. %B Nephrology %D 2010 %C Australia %I Wiley-Blackwell Publishing Asia %V 15 %N Suppl 1 %P S195-S203 %@ 1440-1797 %X %Z FOR Codes: 1103 %0 Journal Article %~ PubMed %A Chadban, S %A Howell, M %A Twigg, S %A Thomas, M %A Jerums, G %A Cass, A %A Campbell, D %A Nicholls, K %A Tong, A %A Mangos, G %A Stack, A %A MacIsaac, R J %A Girgis, S %A Colagiuri, R %A Colagiuri, S %A Craig, J %A , CARI %T The CARI guidelines. Prevention and management of chronic kidney disease in type 2 diabetes. %B Nephrology %D 2010 %C Australia %I Wiley-Blackwell Publishing Asia %V 15 %N Suppl 1 %P S162-S194 %@ 1440-1797 %X %Z FOR Codes: 1103 %0 Journal Article %~ PubMed %A Lester-Smith, David %A Campbell, Dianne E %A Elliott, Elizabeth J %T Using the clinical challenges encountered by junior residents to inform curriculum for paediatric pre-intern students. %B Journal of paediatrics and child health %D 2010 %C United Kingdom, Australia %I Wiley-Blackwell Publishing Ltd. %V 46 %N 5 %P 262-7 %@ 1034-4810 %X To develop and evaluate a novel skills-based education programme for medical students completing a paediatric pre-internship (PrInt) at the Children''s Hospital at Westmead (CHW), Sydney which incorporated a mini-clinical evaluation exercise style formative assessment component and was based upon a local needs assessment of junior staff. %Z FOR Codes: 1114 %0 Journal Article %~ PubMed %A Allen, Clare Wendy %A Kemp, Andrew Stewart %A Campbell, Dianne Elizabeth %T Dietary advice, dietary adherence and the acquisition of tolerance in egg-allergic children: a 5-yr follow-up. %B Pediatric Allergy and Immunology %D 2009 %C United Kingdom, Fran %I Wiley-Blackwell Publishing Ltd. %V 20 %N 3 %P 213-218 %@ 1399-3038 %X IgE-mediated egg allergy is a common childhood food allergy affecting about 1-2% of 2-yr-old children. Egg avoidance is the mainstay of treatment for egg allergy; however, it is unclear what type of dietary advice parents of children with egg allergy receive and to what extent this dietary advice is adhered to. This study aimed to assess: (i) the type and source of dietary advice parents receive in a tertiary hospital setting, (ii) how closely parents adhere to advice given, (iii) what patient characteristics influenced adherence to diet and (iv) whether strict adherence to dietary advice was an identifiable factor in whether children outgrew their egg allergy. In 2006, a questionnaire was sent to 261 parents of children seen in a tertiary paediatric allergy clinic in 2003 and diagnosed with egg allergy which included 84 children who had undergone an in-hospital open oral egg challenge during this time period (2003-2006). Questions included demographic data, details of egg allergy, dietary avoidance and attainment of unrestricted egg ingestion. Of 199 questionnaires confirmed received, 167 were returned (84%). The mean age of the cohort was 6.6 yr with an average of 5.5 yr of follow-up since the first reaction. Sixty-eight percent of subjects reported avoidance of all food containing egg all the time. Forty-seven percent of the children had been accidentally exposed to egg. The severity of the initial reaction did not appear to influence adherence to an advised diet. Of the 84 children who underwent in-hospital open egg challenges, 57 children were able to ingest egg without clinical reaction and were classified as having outgrown their egg allergy. These children did not differ from those who were challenge positive to egg in terms of either the dietary advice they received or the degree to which they had undertaken strict avoidance of egg. In addition, children who had outgrown their egg allergy did not differ from those who remained egg-allergic on in-hospital challenge in terms of either the frequency of accidental ingestion or the severity of initial reaction. Strict avoidance of egg and accidental ingestion of egg did not appear to influence the acquisition of tolerance. %Z FOR Codes: 1103 1107 %0 Book %A Chadban, Steven %A Howell, Martin %A Twigg, Stephen %A Thomas, Mark %A Jerums, George %A Cass, Alan %A Campbell, Dianne %A Nicholls, Kathy %A Tong, Allison %A Mangos, George %A Stack, Annabelle %A McIsaac, Richard %A Girgis, Seham %A Colagiuri, Ruth %A Craig, Jonathan %T National Evidence Based Guideline for Diagnosis, Prevention and Management of Chronic Kidney Disease in Type 2 Diabetes %B %D 2009 %C Australia %I Diabetes Australia and the NHMRC %V %N %P %@ 9780980699739 %X %Z FOR Codes: 110306 110312 %0 Journal Article %~ PubMed %A Kemp, Andrew Stewart %A Allen, Clare Wendy %A Campbell, Dianne Elisabeth %T Parental perceptions in egg allergy: Does egg challenge make a difference? %B Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology %D 2009 %C United Kingdom, Fran %I Wiley-Blackwell Publishing Ltd. %V 20 %N 7 %P 648-53 %@ 1399-3038 %X The aim of the study was to determine the effect of an oral egg challenge in egg sensitized children on parental perceptions relating to their child''s allergy. A questionnaire was completed by parents for 167 children attending a tertiary paediatric clinic with egg sensitization. The questionnaires included 10 questions concerning parental perceptions of their child''s egg allergy. Parental perceptions of those children who had not had an egg challenge (n = 83) were compared with those whose children had a positive (n = 27) and those with a negative (n = 57) egg challenge. A significant difference (p = < or =0.02) was observed between challenge positive(CP) and challenge negative (CN) subjects in reported changes to lifestyle and the fact that more parents in the CN group expected little or no future inconvenience for the child. The responses of parents whose child had undergone an egg challenge differed significantly (p = < or =0.005) from those not challenged with a significant reduction in the following parameters; the effect on out-of-home care arrangements, the perception of being more severe as compared to other common childhood illnesses, whether they found egg allergy to be moderately or very stressful, whether their lifestyle was changed, the expectation of little or no future discomfort for the child and whether others treated the child differently. The performance of an egg challenge was associated with reduced adverse parental concerns. For 6/10 parameters, expectations concerning egg allergy in children who had been challenged were significantly better than those who had never been challenged irrespective of the challenge outcome. The greater certainty provided by the performance of a food challenge may be a positive outcome in both CP and CN children. %Z FOR Codes: 1103 1107 %0 Journal Article %~ PubMed %A Campbell, Dianne E %T Sublingual immunotherapy for children: Are we there yet? Defining its role in clinical practice. %B Paediatric Respiratory Reviews %D 2009 %C United Kingdom %I Elsevier Ltd %V 10 %N 2 %P 69-74 %@ 1526-0550 %X Immunotherapy in various forms has been used to treat allergic disorders since the early 19th century. Subcutaneous immunotherapy is now well established for the treatment of insect anaphylaxis and allergic rhinitis. The route of administration and possibility of severe adverse reactions to subcutaneous immunotherapy make sublingual immunotherapy an appealing alternative, especially for the paediatric patient. This form of immunotherapy has been increasingly used in Europe, and over the past decade several meta analyses have attempted to provide evidence for its efficacy in the treatment of seasonal and perennial allergic rhinitis and in asthma, both in the adult and paediatric population. Several trials have also shown a potential immunomodulatory effect of sublingual immunotherapy, with evidence of a reduction in the progression from allergic rhinitis to asthma and reduced new aeroallergen sensitisation. This review will give an overview of the current evidence for sublingual immunotherapy in the paediatric population. %Z FOR Codes: 1107 1103 1107 1103 %0 Journal Article %~ PubMed %A Allen, C W %A Campbell, D E %A Kemp, A S %T Food allergy: Is strict avoidance the only answer? %B Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology %D 2008 %C United Kingdom %I Wiley-Blackwell %V 20 %N 0 %P 415-22 %@ 1399-3038 %X It is an immunological paradigm that avoidance of food allergen may reduce the risk or prevent immunological reactions and conversely that a greater exposure increases the magnitude of the immune response. Consequently, food allergen avoidance has been recommended to reduce the risk of sensitization in infants and to prevent clinical reactions in children with positive skin prick tests (SPT). In the latter setting, it is hoped that avoidance may either promote or at least not retard the development of tolerance. Animal studies, however, have demonstrated that tolerance to food allergens may be induced by either large (high zone tolerance) or small (low zone tolerance) doses, whereas doses in between may actually stimulate immune responses. In this review, we discuss whether strict allergen avoidance is always the most appropriate strategy for preventing or managing IgE-mediated food allergy. %Z FOR Codes: 1107 1114 %0 Journal Article %~ PubMed %A Allen, Clare Wendy %A Campbell, Dianne Elizabeth %A Kemp, Andrew Stewart %T Egg allergy: are all childhood food allergies the same? %B Journal of paediatrics and child health %D 2007 %C Via Bradano 3/C, Rom %I Pensiero Scientifico Editor %V 43 %N 4 %P 214-218 %@ 1440-1754 %X Egg allergy is one of the most common food allergies in childhood affecting about 1-2% of preschool children and differs in a number of ways from other common childhood food allergies such as cows milk and peanut. Common egg allergens are altered both by heat and gastric enzymes. Compared with peanuts/tree nuts and milk, egg allergy appears less likely to cause severe life-threatening reactions or fatal anaphylaxis. Children are much more likely to outgrow egg allergy by school age as compared with peanut allergy. While the MMR vaccine is no longer contraindicated in egg allergy, influenza vaccine is contraindicated in children with anaphylaxis to egg. An understanding of the similarities and differences in these common food allergies of childhood is helpful in the management of these common and increasing problems. %Z FOR Codes: %0 Journal Article %~ PubMed %A Allen, Clare %A Campbell, Dianne %A Kemp, Andrew %T EpiPen use in children with food allergies. %B The Medical journal of Australia %D 2007 %C Australia %I Australasian Medical Publishing Company Pty. Ltd. %V 187 %N 9 %P 542 %@ 1326-5377 %X %Z FOR Codes: %0 Journal Article %~ PubMed %A Ford, Lara S %A Rogers, Maureen %A Kemp, Andrew S %A Campbell, Dianne E %T Persistent linear bands in infancy acquired after local pressure: a consequence of mast cell activation? %B Pediatric dermatology %D 2007 %C United States %I Wiley-Blackwell Publishing, Inc. %V 24 %N 4 %P 391-393 %@ 1525-1470 %X A 10-month-old girl with marked symptomatic dermographism presented with linear bands at the sock line noted to have developed following an episode of localized urticaria and angioedema at the sock line. We speculate that release of mast cell mediators associated with the dermographism may have triggered the development of the linear bands. %Z FOR Codes: 111403 110304