%0 Journal Article
%~ PubMed
%A Hardy, Todd A
%A Barnett, Michael H
%A Mohamed, Armin
%A Garsia, Roger J
%A Davies, Leo
%T Severe Bickerstaff's encephalitis treated with Rituximab: Serum and CSF GQ1b antibodies.
%B Journal of Neuroimmunology
%D 2012
%C Netherlands
%I Elsevier BV
%V 251
%N 1-2
%P 107-109
%@ 0165-5728
%X Bickerstaff''s encephalitis is a syndrome of ophthalmoplegia, ataxia and impaired consciousness commonly associated with serum GQ1b antibodies. We describe a patient with seropositive Bickerstaff''s encephalitis who did not respond either to plasma exchange or intravenous immunoglobulin but recovered following adjunct treatment with the anti-CD 20 monoclonal antibody, Rituximab. There was a concomitant reduction in serum GQ1b antibodies associated with improvement. Interestingly, GQ1b antibody was also detected in CSF. These findings have potentially significant clinical and immunopathological implications.
%Z FOR Codes: 110903 110703


%0 Journal Article
%~ PubMed
%A Barnett, Michael H
%A Chohan, Gurjit
%A Davies, Leo
%T Blurred vision and pain in the eye.
%B Medical Journal of Australia
%D 2011
%C Australia
%I Australasian Medical Publishing Company Pty. Ltd
%V 195
%N 6
%P 329-332
%@ 1326-5377
%X Subacute unilateral visual impairment accompanied by pain on eye movement is characteristic of optic neuritis. Most cases of optic neuritis resolve spontaneously, and acute treatment with intravenous steroids hastens recovery but does not alter the ultimate visual outcome. Brain magnetic resonance imaging (MRI) may permit a diagnosis of multiple sclerosis (MS) to be made after a single clinical demyelinating event such as optic neuritis. Current evidence supports the introduction of disease-modifying therapy in patients with a single clinical event such as optic neuritis and brain MRI compatible with MS. The diagnosis of MS is a confronting life event associated with significant personal, social and financial burdens. The diagnosing neurologist should provide a detailed explanation of the disease and its clinical spectrum and introduce the patient to the wide range of support services, educational material and MS clinics.
%Z FOR Codes: 110903 111301


%0 Journal Article
%~ PubMed
%A Ahmed, Rebekah
%A Buckland, Michael
%A Davies, Leo
%A Halmagyi, G Michael
%A Rogers, Shannon L
%A Oberste, Steven
%A Barnett, Michael H
%T Enterovirus 71 meningoencephalitis complicating rituximab therapy.
%B Journal of the neurological sciences
%D 2011
%C Netherlands, United Kingdom
%I Elsevier BV
%V 305
%N 
%P 149–151
%@ 0022-510X
%X We describe a fatal case of proven enterovirus 71 meningoencephalitis complicating monoclonal anti-CD20 antibody therapy for non-Hodgkin''s lymphoma. B-cell depletion, an effective treatment strategy in an expanding spectrum of hematological and inflammatory disorders, impairs neutralising antibody-mediated clearance of enterovirus. The global threat of emerging neurotropic viruses such as enterovirus 71 is heightened by an increasing pool of susceptible individuals in non-endemic regions.
%Z FOR Codes: 110903


%0 Journal Article
%~ PubMed
%A Davies, Leo
%A Anderson, Craig S
%T Practical neurology: a case-based series.
%B The Medical Journal of Australia
%D 2011
%C Australia
%I Australasian Medical Publishing Company Pty. Ltd.
%V 195
%N 6
%P 328
%@ 1326-5377
%X A practical guide to common and important problems in clinical neurology.
%Z FOR Codes: 110904


%0 Journal Article
%~ Isi
%A Turner-Stokes, L.
%A Baguley, I. J.
%A De Graaff, S.
%A Katrak, P.
%A Davies, L.
%A McCrory, P.
%A Hughes, A.
%T Goal attainment scaling in the evaluation of treatment of upper limb spasticity with botulinum toxin: A secondary analysis from a double-blind placebo controlled randomised clinical trial
%B Journal of Rehabilitation Medicine
%D 2010
%C Sweden, Belgium
%I Stiftelsen Rehabiliteringsinformation
%V 42
%N 1
%P 81-89
%@ 1650-1977
%X 
%Z FOR Codes: 110321


%0 Journal Article
%~ Isi
%A McCrory, P.
%A Turner-Stokes, L.
%A Baguley, I. J.
%A De Graaff, S.
%A Katrak, P.
%A Sandanam, J.
%A Davies, L.
%A Munns, M.
%A Hughes, A.
%T BOTULINUM TOXIN A FOR TREATMENT OF UPPER LIMB SPASTICITY FOLLOWING STROKE: A MULTI-CENTRE RANDOMIZED PLACEBO-CONTROLLED STUDY OF THE EFFECTS ON QUALITY OF LIFE AND OTHER PERSON-CENTRED OUTCOMES
%B Journal of Rehabilitation Medicine
%D 2009
%C Sweden, Belgium
%I Stiftelsen Rehabiliteringsinformation
%V 41
%N 7
%P 536-544
%@ 1650-1977
%X 
%Z FOR Codes: 110321


%0 Journal Article
%~ PubMed
%A Kirk, E P
%A Malaty-Brevaud, V
%A Martini, N
%A Lacoste, C
%A Levy, N
%A Maclean, K
%A Davies, L
%A Philip, N
%A Badens, C
%T The clinical variability of the MECP2 duplication syndrome: description of two families with duplications excluding L1CAM and FLNA.
%B Clinical genetics
%D 2008
%C Denmark
%I Wiley-Blackwell Munksgaard
%V 75
%N 0
%P 301-3
%@ 1399-0004
%X 
%Z FOR Codes: 110311 111403