%0 Journal Article %A Wu, Yangfeng %A Huxley, Rachel %A Li, Ming %A Ma, Jun %T The growing burden of overweight and obesity in contemporary China %B CVD Prevention and Control %D 2009 %C Netherlands, Switzer %I Elsevier BV %V 4 %N 1 %P 19-26 %@ 1875-4570 %X %Z FOR Codes: 111799 %0 Journal Article %~ Pubmed %A Li, M %A Li, S %A Baur, L A %A Huxley, R R %T A systematic review of school-based intervention studies for the prevention or reduction of excess weight among Chinese children and adolescents. %B Obesity reviews : an official journal of the International Association for the Study of Obesity %D 2008 %V 9 %N 6 %P 548-59 %@ 1467-789X %X The aim of this paper was to conduct a systematic review of intervention studies in China aimed at the prevention or control of excess weight gain among children and adolescents. Two Chinese databases (The China Full Text Database and Wanfang Database) and two English databases (Medline and Meditext) were searched with keywords for intervention studies published between 1990 and 2006. Data were extracted on aspects of study quality, methodology and effectiveness of interventions. Quality assessment was conducted using a previously established assessment tool. Twenty-two studies were included, of which 17 were conducted among overweight and/or obese children and/or adolescents. Interventions strategies varied across studies but the majority focused on improving the level of knowledge, physical activity levels and/or diet of overweight children and adolescents. Most studies reported a beneficial effect of the intervention with one or more of the study outcomes, but all of the studies had serious, or moderate, methodological weaknesses. None of the trials identified by this systematic review demonstrated convincing evidence of the efficacy of any single intervention for the prevention of overweight and obesity in children and adolescents from Mainland China. Future intervention trials should address the methodological weaknesses identified in this review. %Z FOR Codes: 111403 111101 111704 %0 Journal Article %~ Pubmed %A Li, M %A Dibley, M J %A Sibbritt, D %A Yan, H %T Factors associated with adolescents' overweight and obesity at community, school and household levels in Xi'an City, China: results of hierarchical analysis. %B European Journal of Clinical Nutrition %D 2007 %V 62 %N 5 %P 635-43 %@ 0954-3007 %X To identify personal and environmental factors associated with adolescent overweight and obesity in Xi'an city, China. %0 Journal Article %~ Isi %A Dibley, MJ %A Yan, H %A Li, M %A Zhou, XY %A Sibbritt, DW %T Physical activity and sedentary behavior in adolescents in Xi''an City, China %B JOURNAL OF ADOLESCENT HEALTH %D 2007 %C United States %I Elsevier Science %V 41 %N 1 %P 99-101 %@ 1054-139X %X %Z FOR Codes: 111706 110699 %0 Journal Article %~ Pubmed %A Li, Ming %A Dibley, Michael J %A Sibbritt, David %A Yan, Hong %T Factors associated with adolescents' physical inactivity in Xi'an City, China. %B Medicine and Science in Sports and Exercise %D 2006 %V 38 %N 12 %P 2075-85 %@ 0195-9131 %X To explore the sociodemographic and environmental factors at community, school, and household levels associated with physical inactivity. %Z FOR Codes: 111403 111716 %0 Journal Article %~ Pubmed %A Li, Ming %A Dibley, Michael J %A Sibbritt, David %A Yan, Hong %T An assessment of adolescent overweight and obesity in Xi'an City, China. %B %D 2006 %V 1 %N 1 %P 50-8 %@ 1747-7166 %X To assess the magnitude of overweight and obesity, and its associated socio-demographic factors in adolescents in Xi'an city, China. %Z FOR Codes: 111717 111403 %0 Journal Article %~ Pubmed %A Li, Ming %A Yan, Hong %A Dibley, Michael J %A Chang, Su-ying %A Sibbritt, David %T [Prevalence of overweight and obesity and its associated risk factors in students aged 11-17 in Xi'an in 2004]. %B Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae %D 2006 %V 28 %N 2 %P 234-9 %@ 1000-503X %X To assess the magnitude of overweight and obesity and its associated sociodemographic factors in adolescents attending junior high schools in Xi'an, Shanxi province. %Z FOR Codes: 111717 111403 %0 Journal Article %~ Pubmed %A Lou, Y K %A Wen, C %A Li, M %A Adams, D J %A Wang, M X %A Yang, F %A Morris, B J %A Whitworth, J A %T Decreased renal expression of nitric oxide synthase isoforms in adrenocorticotropin-induced and corticosterone-induced hypertension. %B Hypertension %D 2001 %V 37 %N 4 %P 1164-70 %@ 1524-4563 %X Administration of adrenocorticotropic hormone (ACTH) leads to the development of hypertension. Because glucocorticoids can affect the nitric oxide system at several sites, the present study tested the hypothesis that nitric oxide synthase (NOS) expression may be altered in ACTH-induced and corticosterone-induced hypertension in the rat. This was addressed by measuring Nos1, Nos2, and Nos3 mRNA in the kidney, adrenal gland, heart, and hypothalamus of 16 ACTH-treated and 16 vehicle-treated rats as well as in 10 corticosterone-treated and 10 control rats. In addition, in situ hybridization and immunohistochemistry were used to confirm changes by detection of Nos in RNA and NOS protein in tissues. Systolic blood pressure of ACTH and corticosterone rats was elevated (165+/-6 and 162+/-11 mm Hg; P<0.001 versus control). Each Nos isoform mRNA was measured by reverse transcriptase-polymerase chain reaction technique. In ACTH rats, mRNA for Nos2 was reduced in renal cortex by 58+/-5% and in medulla by 68+/-7%; for Nos3, mRNA reductions of 59+/-6% and 51+/-11% were seen (P<0.001 after Hochberg correction for multiple comparisons). In corticosterone rats, Nos2 mRNA decreased in cortex by 68+/-5% and in medulla by 62+/-6%; Nos3 mRNA by 50+/-8% in cortex, and Nos1 by 29+/-7% in medulla (all P<0.001 after Hochberg correction). Reductions seen in kidney were supported by in situ hybridization and immunohistochemistry. Apart from a 62+/-2% decrease in Nos2 mRNA in adrenal of ACTH rats (corrected P<0.05), no significant changes were seen in the other nonrenal tissues for any isoform. In conclusion, we have shown for the first time that the physiological components of glucocorticoid action (ACTH and corticosterone) when given chronically in vivo reduce Nos2 and Nos3 expression in the kidney. Such changes are consistent with a role in hypertension for ACTH and corticosterone.