%0 Journal Article
%~ PubMed
%A Begg, Lindy
%A McLaughlin, Patrick
%A Manning, Leon
%A Vicaretti, Mauro
%A Fletcher, John
%A Burns, Joshua
%T A novel approach to mapping load transfer from the plantar surface of the foot to the walls of the total contact cast: a proof of concept study.
%B Journal of Foot and Ankle Research
%D 2012
%C United Kingdom
%I BioMed Central Ltd.
%V 5
%N 1
%P 32
%@ 1757-1146
%X 
%Z FOR Codes: 110399


%0 Journal Article
%~ PubMed
%A Ong, Adrian
%A Blyth, Christopher C
%A Bency, Rosamma
%A Vicaretti, Mauro
%A Harun, Azian
%A Meyer, Wieland
%A Shingde, Meena
%A Gilroy, Nicky
%A Chapman, Jeremy
%A Chen, Sharon C-A
%T Fatal mycotic aneurysms due to scedosporium and pseudallescheria infection.
%B Journal of Clinical Microbiology
%D 2011
%C United States
%I American Society for Microbiology
%V 49
%N 5
%P 2067-2071
%@ 0095-1137
%X Angioinvasive complications of Scedosporium infections are rare. We report two cases of mycotic aneurysm, following apparent localized infection, due to Scedosporium apiospermum and Pseudallescheria boydii. The thoracoabdominal aorta was affected in one patient, and cerebral vessels were affected in the other. Despite voriconazole therapy and surgical resection, the patients died. Previously reported cases are reviewed.
%Z FOR Codes: 60505


%0 Journal Article
%A Vicaretti, Mauro
%T Compression therapy for venous disease
%B Australian Prescriber
%D 2010
%C Australia
%I National Prescribing Service Ltd.
%V 33
%N 6
%P 186-190
%@ 0312-8008
%X 
%Z FOR Codes: 111717


%0 Journal Article
%~ PubMed
%A Fitridge, R
%A Quigley, F
%A Vicaretti, M
%T Should we develop a core international curriculum for Vascular and Endovascular Surgery?
%B European Journal of Vascular and Endovascular Surgery
%D 2010
%C United Kingdom, Denm
%I Elsevier Ltd
%V 39
%N Suppl 1
%P S10-S14
%@ 1078-5884
%X Vascular and endovascular surgery has undergone a period of extraordinary change during the last 20 years. This is in part due to changes in patient profiles, the development of new, potent drugs and the technological advances in imaging and interventional products. These changes have effectively resulted in the development of an independent specialty, which has needed to define the competencies required for specialist recognition and credentialing. This paper discusses the key aspects of contemporary training in Vascular and Endovascular Surgery, and raises the possibility of developing an agreed core international curriculum.
%Z FOR Codes: 110323


%0 Journal Article
%~ PubMed
%A Tiwari, Alok
%A Saw, Chong
%A Li, Michelle
%A Mohan, Irwin
%A Daly, Tom
%A Swinnen, John
%A Richardson, Arthur
%A So, Simon
%A Young, Noel
%A Vicaretti, Mauro
%A Fletcher, John
%T Use of inferior vena cava filters in a tertiary referral centre in Australia.
%B ANZ Journal of Surgery
%D 2010
%C Australia
%I Wiley-Blackwell Publishing Asia
%V 80
%N 5
%P 364-367
%@ 1445-2197
%X Introduction: To investigate the use of inferior vena cava (IVC) filters in a tertiary referral centre, looking at indication, types of filters and, with temporary/optional filters, removal rates. Methods: Data was collected from a prospective database of all IVC filters inserted from January 2003 to January 2007. Patients'' records and radiological imaging were all reviewed. Results: 66 patients (40 males) had IVC filters inserted during the study period. The median age of the male patients was 57.5 (21-79) years, and females 56 (24-81). There were 49 (74.2%) temporary/optional filters and 17 (25.8%) permanent filters. The most common indication for filter was a contraindication to anticoagulation for both permanent (64.7%) and temporary/optional filters (77.6%). In the temporary/optional filter group, 38 of 49 (77.6%) patients had documented venous thromboembolism, while in the permanent filter group, this was 14 of 17 (82.4%). Of the optional filters, 22 of 49 (45.8%) have been removed. Conclusion: More than half (54.2%) of temporary/optional filters were not removed and with potential for long-term complications. A protocol has now being instituted for vascular surgeons to authorize the insertion of filters and to then be responsible for ensuring their removal.
%Z FOR Codes: 104


%0 Journal Article
%~ PubMed
%A Swinnen, Jan
%A Chao, Alex
%A Tiwari, Alok
%A Crozier, John
%A Vicaretti, Mauro
%A Fletcher, John
%T Vertical or Transverse Incisions for Access to the Femoral Artery: A Randomized Control Study.
%B Annals of vascular surgery
%D 2010
%C United States
%I Elsevier
%V 24
%N 3
%P 336-41
%@ 1615-5947
%X To look at wound complications with either a transverse or vertical groin incision in vascular surgery.
%Z FOR Codes: 1114 1108


%0 Journal Article
%~ PubMed
%A Burns, J
%A Wegener, C
%A Begg, L
%A Vicaretti, M
%A Fletcher, J
%T Randomized trial of custom orthoses and footwear on foot pain and plantar pressure in diabetic peripheral arterial disease.
%B Diabetic Medicine
%D 2009
%C United Kingdom, Uni
%I Wiley-Blackwell Publishing Ltd.
%V 26
%N 9
%P 893-899
%@ 1464-5491
%X AIM: Custom-made foot orthoses reduce plantar pressure, ulceration and amputation in patients with diabetes mellitus. There is limited evidence of their effect on foot pain. In a randomized, single-blind, sham-controlled trial, the efficacy of custom orthoses on foot pain and plantar pressure in diabetic patients with peripheral arterial disease was investigated. METHODS: Sixty-one participants were randomly assigned to either custom foot orthoses (n = 30) or sham insoles (n = 31). Both groups also received standardized walking footwear. Outcomes included foot pain and function, mean pressure, toe-brachial index, average daily steps, disability, comfort, quality of life, adherence and adverse events. A multivariate predictive model was constructed to explore factors contributing to pain relief during the trial. RESULTS: At 8 weeks, 95% of participants provided follow-up data, adherence was high and there were few adverse events. Foot pain and function scores significantly improved at 8 weeks with both custom orthoses and the sham, but there was no significant difference between groups. Custom orthoses reduced pressure significantly more than the sham. There were no significant differences between groups for toe-brachial index, daily steps, disability, comfort or quality of life. Regression modelling identified inappropriate pre-trial footwear as the strongest predictor of foot pain relief during the trial. CONCLUSIONS: Custom foot orthoses significantly reduced plantar pressure compared with the sham, but there were no significant differences between groups for pain or function. The high-quality walking footwear provided to both groups may explain this finding. Footwear should have greater emphasis as the clinical intervention.
%Z FOR Codes: 1117


%0 Journal Article
%~ PubMed
%A Burns, Joshua
%A Begg, Lindy
%A Vicaretti, Mauro
%T Comparison of orthotic materials on foot pain, comfort, and plantar pressure in the neuroischemic diabetic foot: a case report.
%B Journal of the American Podiatric Medical Association
%D 2008
%C United States
%I American Podiatric Medical Association
%V 98
%N 2
%P 143-148
%@ 8750-7315
%X Foot pain and lower-limb neuroischemia in diabetes mellitus is common and can be debilitating and difficult to treat. We report a comparison of orthotic materials to manage foot pain in a 59-year-old man with type 1 diabetes mellitus, peripheral neuropathy, peripheral arterial disease, and a history of foot ulceration. We investigated a range of in-shoe foot orthoses for comfort and plantar pressure reduction in a cross-sectional study. The most comfortable and most effective pressure-reducing orthoses were subsequently evaluated for pain relief in a single system alternating-treatment design. After 9 weeks, foot pain was completely resolved with customized multidensity foot orthoses. The outcome of this case study suggests that customized multidensity foot orthoses may be a useful intervention to reduce foot pain and maintain function in the neuroischemic diabetic foot.
%Z FOR Codes: 110318


%0 Journal Article
%~ PubMed
%A Tiwari, Alok
%A Harrington, Tim
%A Vicaretti, Mauro
%T Endovascular treatment of a "fishy" ulcer caused by a traumatic arteriovenous fistula.
%B Vascular and Endovascular Surgery
%D 2008
%C United States
%I Sage Science Press
%V 42
%N 3
%P 289-292
%@ 1538-5744
%X Arteriovenous fistula secondary to trauma is an uncommon cause of leg ulcers. In this article, an unusual case of a nonhealing leg ulcer caused by a stingray is described. This case highlights the difficulty in diagnosing and treating nonhealing ulcers secondary to arteriovenous fistula.
%Z FOR Codes: 110399


%0 Journal Article
%~ PubMed
%A Medbury, H J
%A Tarran, S L S
%A Guiffre, A K
%A Williams, M M Y
%A Lam, T H
%A Vicaretti, M
%A Fletcher, J P
%T Monocytes contribute to the atherosclerotic cap by transformation into fibrocytes.
%B International Angiology
%D 2008
%C Italy
%I Edizioni Minerva Medica
%V 27
%N 2
%P 114-123
%@ 0392-9590
%X AIM: The stability of an atherosclerotic plaque is a key-determining factor in the clinical outcome of cardiovascular disease. In this respect, smooth muscle (SM) alfa actin positive cells play an important role in maintaining plaque stability through formation of a fibrous cap. Recent evidence suggests that circulating progenitors may be a source of these cells. We hypothesized that they may be fibrocytes bone-marrow derived cells that acquire SM-like characteristics, including the expression of SM alfa actin. METHODS: We examined human carotid endarterectomy specimens for the presence of fibrocytes by immunohistochemistry staining for CD34/procollagen I and leukocyte specific protein-1/procollagen I) and examined fibrocyte differentiation in vitro. RESULTS: Fibrocytes were found in regions of plaque growth/healing. They possessed a SM-like spindle shape, produced collagen, and consistent with being fibrocytes they co-localized with transformation growth factor beta, but not serum amyloid P factors, known to promote and inhibit their formation, respectively. While fibrocytes were detected in regions of new growth in 35/40 specimens, only 1/3 of the specimens expressed the SM cell marker calponin, and smoothelin was absent, in these regions. CONCLUSION: Our results demonstrate that fibrocytes contribute to formation of the fibrous cap. With fibrocytes being a monocyte derived cell, we suggest that monocytes may play a more crucial role in the clinical outcome of atherosclerosis than previously realized as they not only contribute directly to plaque instability (through foam cell formation), but also promote plaque stability by transformation into a fibrocyte.
%Z FOR Codes: 110201


%0 Journal Article
%~ PubMed
%A Varcoe, Ramon L
%A Mah, Jean
%A Young, Noel
%A So, Simon S
%A Vicaretti, Mauro
%A Swinnen, John
%T Prevalence of carotid stent fractures in a single-center experience.
%B Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
%D 2008
%C United States
%I Alliance Communications Group
%V 15
%N 4
%P 485-489
%@ 1526-6028
%X PURPOSE: To assess the prevalence of carotid stent fractures and quantify any associated restenosis or clinical events in a single-center experience. METHODS: Seventy-eight consecutive patients were recorded in a prospective database between 2003 and 2007. Nearly two thirds (51, 65%) were available for follow-up, which included magnified multiplanar radiography and selective duplex ultrasonographic studies to evaluate fracture and restenosis in 53 self-expanding stents (49 open-cell and 4 closed-cell designs). The images were assessed independently by 2 vascular radiologists blinded to the patients'' clinical data. RESULTS: There was 1 (1.9%) stent fracture with no associated adverse events or restenosis. Six (11%) stents had an irregular "fish-scale" appearance that was easily confused for fracture and seen only in the open-cell stents. CONCLUSION: Stent fractures do occur in the carotid artery; however, they are rare and, in our experience, have no clinical sequelae. Radiological assessment should be incorporated into clinical and ultrasound surveillance protocols.
%Z FOR Codes: 110201


%0 Journal Article
%~ PubMed
%A Wright, B
%A Vicaretti, M
%A Schwaiger, N
%A Wu, J
%A Trickett, R
%A Morrissey, L
%A Rohanizadeh, R
%A Fletcher, J
%A Maitz, P
%A Harris, M
%T Laser-assisted end-to-end BioWeld anastomosis in an ovine model.
%B Lasers in Surgery and Medicine
%D 2007
%C USA
%I John Wiley & Sons, Inc
%V 39
%N 8
%P 667-673
%@ 0196-8092
%X The BioWeld tube, an albumin-based exovascular stent, has been used for microsurgical anastomoses and compared to conventional sutures. The study presented investigated the potential of the BioWeld tube for vascular anastomosis in larger vessels. Laser-assisted BioWeld anastomoses were compared to conventional-sutured anatomoses of the carotid artery of Merino-x ewes. The BioWeld procedure resulted in 100% survival and 100% patency at 1 and 6 week post-operative periods, with no noticeable foreign body response. Sutured animals showed 100% survival and patency. The ischemic time for BioWeld anastomosis averaged 15 minutes compared with 10 minutes for sutures. This study indicates that the BioWeld tube is an easy to use anastomotic technique with equivalent success rates and comparable anastomotic times.
%Z FOR Codes: 110323


%0 Journal Article
%~ Isi
%A Varcoe, R. L.
%A Medbury, H.
%A Vicaretti, M.
%A Guiffre, A.
%A Fletcher, J. P.
%T The fibrocyte in intimal hyperplasia.
%B Atherosclerosis Supplements
%D 2006
%C Ireland
%I Elsevier Ireland Ltd
%V 7
%N 3
%P 96-96
%@ 1567-5688
%X 
%Z FOR Codes:


%0 Journal Article
%~ Isi
%A Medbury, H. J.
%A Guiffre, A. K.
%A Williams, M. W. Y.
%A Vicaretti, M.
%A Fletcher, J. P.
%T The opposing roles of monocytes in atherosclerosis.
%B Atherosclerosis Supplements
%D 2006
%C Ireland
%I Elsevier Ireland Ltd
%V 7
%N 3
%P 34-34
%@ 1567-5688
%X 
%Z FOR Codes:


%0 Journal Article
%~ PubMed
%A Varcoe, R L
%A Mikhail, M
%A Guiffre, A K
%A Pennings, G
%A Vicaretti, M
%A Hawthorne, W J
%A Fletcher, J P
%A Medbury, H J
%T The role of the fibrocyte in intimal hyperplasia.
%B Journal of thrombosis and haemostasis : JTH
%D 2006
%C United States
%I Blackwell Publishing, Inc.
%V 4
%N 5
%P 1125-33
%@ 1538-7933
%X BACKGROUND: Experimental animal studies have shown that the intimal hyperplasia (IH) responsible for occlusion after successful revascularization procedures may be partially caused by a bone marrow-derived cell that migrates to the site of vascular injury. Concurrent studies have demonstrated an extensive role in wound healing for the circulating fibrocyte. OBJECTIVES: We aimed to trace the path of the circulating cell that contributes to IH and determine if it is the fibrocyte. METHODS AND RESULTS: We established an in vitro model whereby purified monocytes from six healthy human volunteers were cultured into fibrocytes. These cells were morphometrically similar to the vascular smooth muscle cell (VSMC) found in IH and expressed alpha-smooth muscle actin (alpha-SMA) as well as CD34, CD45 and Collagen I (Col I), markers indicative of the fibrocyte. In an in vivo ovine carotid artery synthetic patch graft model, carboxyfluorescein diacetate, succinimidyl ester (CFSE) labeled circulating leukocytes were observed throughout the graft as well as in the neointima in 18 sheep. These cells were shown to produce collagen and alpha-SMA at 1, 2 and 4 weeks. These cells then underwent immunohistochemical analysis and were found to express a set of markers unique to the fibrocyte (CD34, CD45, Vimentin and alpha-SMA) and also to double stain for CD34 and alpha-SMA. CONCLUSIONS: IH in an ovine carotid artery patch graft model is partially derived from a hematopoietic circulating progenitor cell that acquires mesenchymal features as it matures at the site of injury.
%Z FOR Codes: 110323