Associate Professor Adam Guastella

Principal Research Fellow
Psychiatry, School of Medical Sciences
Brain & Mind Research Institute

Telephone +61 2 9351 0539
Fax +61 2 9351 0855

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Research interests

Associate Professor Adam Guastella is a Clinical Psychologist and Principle Research Fellow at the Brain & Mind Research Institute. His primary interest is in developing novel treatments to improve social functioning in young patients with mental health problems. This research has led him to study (theory of mind, social cognition and social anxiety in patients presenting with a range of mental illnesses (anxiety, autism, psychosis, substance dependence). It also led expansion into psychopharmacology and psychophysiology, both of which he manages related laboratories as part of this research.

His research may take the form of cognitive-experimental investigations aimed at understanding how biology can interact with psychological processes to cause, maintain and recover from mental health problems. Alternatively, it may take the form of developing new interventions to be integrated and evaluated in our community treatment clinics. His research is internationally recognised in two areas of research: Oxytocin improves social-communication processes in humans: Assoc Prof. Guastella initiated a program of research that showed the powerful enhancing effects of oxytocin administration on face-perception and the cognitive processing of social-stimuli in humans. This research showed that oxytocin administration increases gaze to the eye-region of human faces and enhances processing of positive social information. Associate Prof. Guastella was also one of the first to show that oxytocin enhances emotion understanding in young people with autism. Dr Guastella is currently evaluating whether oxytocin can be used to treat a range of mental health problems that are primarily associated with a difficulty in developing social-relationships. This research advances our basic understanding for evolutionary and biosocial theories of bonding and attachment in humans and may lead an exciting new treatment approach for mental health problems. D-Cycloserine (DCS) facilitates fear-extinction in humans: Dr Guastella conducted some of the first clinical treatment trials of medications that are thought to facilitate learning to overcome fear in humans. Consisting of both experimental investigation of fear-extinction in humans and large clinical treatment trials for phobia, social anxiety, panic disorder, and obsessive-compulsive disorder, these trials have shown that the administration of a simple, low-cost antibiotic before psychological therapy enhances treatment outcomes for anxiety. This has the potential to revolutionize how mental health professionals treat anxiety disorders in the community.

Selected grants

2015

  • Serotonin transporter methylation and brain development: studies in autism and interaction with oxytocin; Booij L, Guastella A; DVC Research/International Research Collaboration Award (IRCA).

2014

  • Clinical CDF Level 2 - Determining the role of oxytocin and associated analogues in treatments for social dysfunction; Guastella A; National Health and Medical Research Council (NHMRC)/Career Development Fellowship.
  • Clinical observation and comprehensive psychophysiological recording and behavioural coding equipment; Hawes D, Hickie I, Lagapolos J, Glozier N, Menzies R, Naismith S, Matthews S, Einfeld S, Morley K, de Rosnay M, Guastella A; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • Optimising early interventions for young people with emerging mood disorder; Hickie I, McGorry P, Christensen H, Berk M, Naismith S, Glozier N, Burns J, Guastella A, Davey C, Amminger P; National Health and Medical Research Council (NHMRC)/Centres of Research Excellence.
  • A course of oxytocin to improve social communication in young children with autism; Guastella A, Whitehouse A, Gregory S; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Neuroimaging oxytocin modulated plasticity, response markers and implication for treatment of Autism Spectrum Disorders and co-morbid intellectual disability; Guastella A, Johnston B; Endeavour Foundation/Research Support.

2012

  • Evaluation of a melanocortin agonist to improve social cognition in ASD; Guastella A, Hickie I, Young L; Simons Foundation/Research Support.
  • Investigating oxytocin to improve social difficulties in patients with autism; Guastella A; BUPA Foundation Limited (Australia)/Grants Program.

2011

  • Examination of the Cognitive and Biological Circuitry Underlying Social-Cognitive Training in First Episode Psychosis; Guastella A, Langdon R, Scott E, Ward P, Naismith S, Redoblado Hodge M; Australian Research Council (ARC)/Linkage Projects (LP).
  • LNK: 2011/Round2/ARC LP110200562, Attentional and conditioning mechanisms that mediate overcoming anxiety (Pearl 100) - Attentional and Conditioning Mechanisms that Mediate Overcoming Anxiety; Guastella A, MacLeod C, Scott E; Australian Research Council (ARC)/Linkage Projects (LP).

2010

  • LNK: 2011/Round1/ARC Linkage Project LP110100513 The Impact of Oxytocin (OT) on Social Cognition and; Redoblado Hodge M, Naismith S, Kelly A, Guastella A; The Clinical Centre/Project Support.
  • Oxytocin treatment for Prader-Willi Syndrome; Einfeld S, Smith A, Guastella A, Smith A; National Health and Medical Research Council (NHMRC)/Project Grants.
  • The effects of Oxytocin on Social Cognition in Schizophrenia; Guastella A, Langdon R, Redoblado Hodge M, Ward P, Scott E; National Health and Medical Research Council (NHMRC)/Project Grants.
  • A course of oxytocin nasal spray to improve social-communication in young people with autism; Guastella A, Einfeld S, Gray K, Rinehart N; National Health and Medical Research Council (NHMRC)/Project Grants.

2009

  • A Trial of Oxytocin To Improve Behaviour and Cognition in Prader-Willi Syndrome; Einfeld S, McGregor I, Guastella A, Smith A; Foundation for Prader-Willi Research/Research Grant.
  • The effect of Oxytocin on the processing of positive and threatening social cues; Guastella A; DVC Research/Bridging Support Grant.
  • The effects of oxytocin nasal spray on mechanisms of social-communication in young people with autism; Guastella A, Einfeld S, Reinhart N, Gray K, Lambert T, Tonge B; National Health and Medical Research Council (NHMRC)/Project Grants.
  • D-Cycloserine Augmentation of Psychological Treatments for young Adults with Social Anxiety Disorder; Guastella A; DVC Research/Bridging Support Grant.
  • Randomised, double-blind, placebo controlled trial of lithium carbonate for the management of human cannabis withdrawal; Lintzeris N, McGregor I, Winstock A, Guastella A; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Einfeld, S., Smith, E., McGregor, I., Steinbeck, K., Taffe, J., Rice, L., Horstead, S., Rogers, N., Hodge, M., Guastella, A. (2014). A Double-Blind Randomized Controlled Trial of Oxytocin Nasal Spray in Prader Willi Syndrome. American Journal of Medical Genetics. Part A, 164(9), 2232-2239. [More Information]
  • Guastella, A., Gray, K., Rinehart, N., Alvarez, G., Tonge, B., Hickie, I., Keating, C., Cacciotti-Saija, C., Einfeld, S. (2014). The effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: a randomized controlled trial. Journal of Child Psychology and Psychiatry, Early online. [More Information]
  • Carson, D., Guastella, A., Taylor, E., McGregor, I. (2013). A brief history of oxytocin and its role in modulating psychostimulant effects. Journal of Psychopharmacology, 27(3), 231-247. [More Information]
  • Quintana, D., McGregor, I., Guastella, A., Malhi, G., Kemp, A. (2013). A Meta-Analysis on the Impact of Alcohol Dependence on Short-Term Resting-State Heart Rate Variability: Implications for Cardiovascular Risk. Alcoholism: Clinical and Experimental Research, 37(S1), E23-E29. [More Information]
  • Quintana, D., Kemp, A., Alvares, G., Guastella, A. (2013). A role for autonomic cardiac control in the effects of oxytocin on social behavior and psychiatric illness. Frontiers in Neuroscience, 7(April 2013), 1-9. [More Information]
  • Hickie, I., Scott, E., Hermens, D., Naismith, S., Guastella, A., Kaur, M., Sidis, A., Whitwell, B., Glozier, N., Davenport, T., et al (2013). Applying clinical staging to young people who present for mental health care. Early Intervention in Psychiatry, 7(1), 31-43. [More Information]
  • Clarke, P., MacLeod, C., Guastella, A. (2013). Assessing the role of spatial engagement and disengagement of attention in anxiety-linked attentional bias: a critique of current paradigms and suggestions for future research directions. Anxiety Stress and Coping, 26(1), 1-19. [More Information]
  • Hickie, I., Scott, J., Hermens, D., Scott, E., Naismith, S., Guastella, A., Glozier, N., McGorry, P. (2013). Clinical classification in mental health at the cross-roads: which direction next? BMC Medicine, 11(1), 1-14. [More Information]
  • Wudarczyk, O., Earp, B., Guastella, A., Savulescu, J. (2013). Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations. Current Opinion in Psychiatry, 26(5), 474-484. [More Information]
  • Scott, E., Hermens, D., Naismith, S., Guastella, A., De Regt, T., White, D., Lagopoulos, J., Hickie, I. (2013). Distinguishing young people with emerging bipolar disorders from those with unipolar depression. Journal of Affective Disorders, 144(3), 208-215. [More Information]
  • Scott, E., Hermens, D., Naismith, S., Guastella, A., White, D., Whitwell, B., Lagopoulos, J., Scott, J., Hickie, I. (2013). Distress and disability in young adults presenting to clinical services with mood disorders. International Journal of Bipolar Disorders, 1, 1-8. [More Information]
  • McCade, D., Savage, G., Guastella, A., Lewis, S., Naismith, S. (2013). Emotion Recognition Deficits Exist in Mild Cognitive Impairment, But Only in the Amnestic Subtype. Psychology and Aging, 28(3), 840-852. [More Information]
  • McCade, D., Savage, G., Guastella, A., Hickie, I., Lewis, S., Naismith, S. (2013). Emotion Recognition in Mild Cognitive Impairment: Relationship to Psychosocial Disability and Caregiver Burden. Journal of Geriatric Psychiatry and Neurology, 26(3), 165-173. [More Information]
  • Hickie, I., Hermens, D., Naismith, S., Guastella, A., Glozier, N., Scott, J., Scott, E. (2013). Evaluating differential developmental trajectories to adolescent-onset mood and psychotic disorders. BMC Psychiatry, 13(1), 1-11. [More Information]
  • Liu, J., Guastella, A., Dadds, M. (2013). Exploring the role of intra-nasal oxytocin on the partner preference effect in humans. Psychoneuroendocrinology, 38(4), 587-591. [More Information]
  • Quintana, D., Guastella, A., McGregor, I., Hickie, I., Kemp, A. (2013). Heart rate variability predicts alcohol craving in alcohol dependent outpatients: Further evidence for HRV as a psychophysiological marker of self-regulation. Drug and Alcohol Dependence, 132(1-2), 395-398. [More Information]
  • Quintana, D., Guastella, A., McGregor, I., Hickie, I., Kemp, A. (2013). Moderate alcohol intake is related to increased heart rate variability in young adults: Implications for health and well-being. Psychophysiology, 50(12), 1202-1208. [More Information]
  • Hermens, D., Naismith, S., Lagopoulos, J., Lee, C., Guastella, A., Scott, E., Hickie, I. (2013). Neuropsychological profile according to the clinical stage of young persons presenting for mental health care. BMC Psychology, 1, 1-9. [More Information]
  • Guastella, A., Hickie, I., McGuinness, M., Otis, M., Woods, E., Disinger, H., Chan, H., Chen, T., Banati, R. (2013). Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research. Psychoneuroendocrinology, 38(5), 612-625. [More Information]
  • Alvares, G., Quintana, D., Kemp, A., van Zwieten, A., Balleine, B., Hickie, I., Guastella, A. (2013). Reduced heart rate variability in social anxiety disorder: associations with gender and symptom severity. PLoS One, 8(7), 1-8. [More Information]
  • van Zwieten, A., Meyer, J., Hermens, D., Hickie, I., Hawes, D., Glozier, N., Naismith, S., Scott, E., Lee, R., Guastella, A. (2013). Social cognition deficits and psychopathic traits in young people seeking mental health treatment. PLoS One, 8(7), 1-9. [More Information]
  • Guastella, A., Hermens, D., van Zwieten, A., Naismith, S., Lee, R., Cacciotti-Saija, C., Scott, E., Hickie, I. (2013). Social cognitive performance as a marker of positive psychotic symptoms in young people seeking help for mental health problems. Schizophrenia Research, 149(1-3), 77-82. [More Information]
  • Shahrestani, S., Kemp, A., Guastella, A. (2013). The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis. Neuropsychopharmacology, 38(10), 1929-1936. [More Information]
  • Guastella, A., Alvares, G., Hickie, I., Chan, H., Chen, T., Banati, R. (2013). Unitary hormonal models, peripheral markers, and evaluation of response to drug: A response to Weisman and Feldman. Psychoneuroendocrinology, 38, 627-628. [More Information]
  • Lowe (nee Thompson), R., Guastella, A., Chen, N., Menzies, R., Packman, A., O'Brian, S., Onslow, M. (2012). Avoidance of eye gaze by adults who stutter. Journal of Fluency Disorders, 37(4), 263-274. [More Information]
  • Chen, N., Clarke, P., MacLeod, C., Guastella, A. (2012). Biased Attentional Processing of Positive Stimuli in Social Anxiety Disorder: An Eye Movement Study. Cognitive Behaviour Therapy, 41(2), 96-107. [More Information]
  • Clarke, P., Hickie, I., Scott, E., Guastella, A. (2012). Clinical staging model applied to young people presenting with social anxiety. Early Intervention in Psychiatry, 6(3), 256-264. [More Information]
  • Liu, J., Guastella, A., Dadds, M. (2012). Effects of oxytocin on human social approach measured using intimacy equilibriums. Hormones and Behavior, 62(5), 585-591. [More Information]
  • Quintana, D., Guastella, A., Outhred, T., Hickie, I., Kemp, A. (2012). Heart Rate Variability is Associated With Emotion Recognition: Direct Evidence for a Relationship Between the Autonomic Nervous System and Social Cognition. International Journal of Psychophysiology, 86(2), 168-172. [More Information]
  • Bryant, R., Hung, L., Guastella, A., Mitchell, P. (2012). Oxytocin as a moderator of hypnotizability. Psychoneuroendocrinology, 37(1), 162-166. [More Information]
  • Kemp, A., Quintana, D., Kuhnert, R., Griffiths, K., Hickie, I., Guastella, A. (2012). Oxytocin increases heart rate variability in humans at rest: implications for social approach-related motivation and capacity for social engagement. PLoS One, 7(8), 1-6. [More Information]
  • Alvares, G., Chen, N., Balleine, B., Hickie, I., Guastella, A. (2012). Oxytocin selectively moderates negative cognitive appraisals in high trait anxious males. Psychoneuroendocrinology, 37(12), 2022-2031. [More Information]
  • Clarke, P., Chen, N., Guastella, A. (2012). Prepared for the Best: Readiness To Modify Attentional Processing and Reduction in Anxiety Vulnerability in Response to Therapy. Emotion, 12(3), 487-494. [More Information]
  • Scott, E., Hermens, D., Glozier, N., Naismith, S., Guastella, A., Hickie, I. (2012). Targeted primary care-based mental health services for young Australians. Medical Journal of Australia, 196(2), 136-140. [More Information]
  • Scott, E., Hermens, D., Naismith, S., White, D., Whitwell, B., Guastella, A., Glozier, N., Hickie, I. (2012). Thoughts of death or suicidal ideation are common in young people aged 12 to 30 years presenting for mental health care. BMC Psychiatry, 12(December 2012), 1-6. [More Information]
  • Guastella, A., Kenyon, A., Unkelbach, C., Alvares, G., Hickie, I. (2011). Arginine Vasopressin selectively enhances recognition of sexual cues in male humans. Psychoneuroendocrinology, 36(2), 294-297. [More Information]
  • Kemp, A., Guastella, A. (2011). The Role of Oxytocin in Human Affect: A Novel Hypothesis. Current Directions in Psychological Science, 20(4), 222-231. [More Information]
  • Kemp, A., Guastella, A. (2011). The Role of Oxytocin in Human Affect: A Novel Hypothesis. Current Directions in Psychological Science, 20(4), 222-231. [More Information]
  • Alvares, G., Hickie, I., Guastella, A. (2010). Acute effects of intranasal oxytocin on subjective and behavioral responses to social rejection. Experimental and Clinical Psychopharmacology, 18(4), 316-321. [More Information]
  • Guastella, A., Kenyon, A., Alvares, G., Carson, D., Hickie, I. (2010). Intranasal Arginine Vasopressin Enhances the Encoding of Happy and Angry Faces in Humans. Biological Psychiatry, 67(12), 1220-1222. [More Information]
  • Guastella, A., Einfeld, S., Gray, K., Rinehart, N., Tonge, B., Lambert, T., Hickie, I. (2010). Intranasal Oxytocin Improves Emotion Recognition in Youth with Autism Spectrum Disorders. Biological Psychiatry, 67, 692-694. [More Information]
  • Carson, D., Cornish, J., Guastella, A., Hunt, G., McGregor, I. (2010). Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats. Neuropharmacology, 58(1), 38-43. [More Information]
  • Kemp, A., Guastella, A. (2010). Oxytocin: Prosocial Behavior, Social Salience, or Approach-Related Behavior? Biological Psychiatry, 67(6), e33-e34. [More Information]
  • Christensen, H., Guastella, A., Mackinnon, A., Griffiths, K., Eagleson, C., Batterham, P., Kalia, K., Kenardy,, J., Bennett, K., Hickie, I. (2010). Protocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder. Trials, 11, 48-1-48-8. [More Information]
  • Carson, D., Hunt, G., Guastella, A., Barber, L., Cornish, J., Arnold, J., Boucher, A., McGregor, I. (2010). Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in the hypothalamus. Addiction Biology, 15(4), 448-463. [More Information]
  • Guastella, A., Howard, A., Dadds, M., Mitchell, P., Carson, D. (2009). A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder. Psychoneuroendocrinology, 34(6), 917-923. [More Information]
  • Guastella, A., Carson, D., Dadds, M., Mitchell, P., Cox, R. (2009). Does oxytocin influence the early detection of angry and happy faces? Psychoneuroendocrinology, 34, 220-225. [More Information]
  • Guastella, A., Dadds, M. (2009). Sequential growth in cognitive-behavioral emotion-processing: A laboratory study. Cognitive Therapy and Research, 33(4), 368-374.
  • Guastella, A., Richardson, R., Lovibond, P., Rapee, R., Gaston, J., Mitchell, P., Dadds, M. (2008). A Randomized Controlled Trial of D-Cycloserine Enhancement of Exposure Therapy for Social Anxiety Disorder. Biological Psychiatry, 63(6), 544-549. [More Information]
  • Guastella, A., Dadds, M. (2008). Cognitive-behavioural emotion writing tasks: A controlled trial of multiple processes. Journal of Behavior Therapy and Experimental Psychiatry, 39(4), 558-566. [More Information]
  • Guastella, A., Mitchell, P., Matthews, F. (2008). Oxytocin Enhances the Encoding of Positive Social Memories in Humans. Biological Psychiatry, 64(6), 256-258. [More Information]
  • Guastella, A., Mitchell, P., Dadds, M. (2008). Oxytocin Increases Gaze to the Eye Region of Human Faces. Biological Psychiatry, 63(1), 3-5. [More Information]
  • Unkelbach, C., Guastella, A., Forgas, J. (2008). Oxytocin selectively facilitates recognition of positive sex and relationship words. Psychological Science, 19(11), 1092-1094. [More Information]
  • Dadds, M., El Masry, Y., Wimalaweera, S., Guastella, A. (2008). Reduced Eye Gaze Explains "Fear Blindness" in Childhood Psychopathic Traits. Journal of the American Academy of Child and Adolescent Psychiatry, 47(4), 455-463. [More Information]
  • Guastella, A., Dadds, M., Lovibond, P., Mitchell, P., Richardson, R. (2007). A randomized controlled trial of the effect of D-cycloserine on exposure therapy for spider fear. Journal of Psychiatric Research, 41(6), 466-471. [More Information]
  • Guastella, A., Lovibond, P., Dadds, M., Mitchell, P., Richardson, R. (2007). A randomized controlled trial of the effect of D-cycloserine on extinction and fear conditioning in humans. Behaviour Research and Therapy, 45(4), 663-672. [More Information]
  • Guastella, A., Moulds, M. (2007). The impact of rumination on sleep quality following a stressful life event. Personality and Individual Differences, 42(6), 1151-1162.
  • Guastella, A., Dadds, M. (2006). Cognitive-Behavioral Models of Emotional Writing: A Validation Study. Cognitive Therapy and Research, 30(3), 397-414. [More Information]
  • Roth, J., Dadds, M., McAloon, J., Guastella, A., Weems, C. (2004). Prevalence and Prediction of Disorders in Early Childhood: A Community Study. Behaviour Change, 21(4), 215-228.

2014

  • Einfeld, S., Smith, E., McGregor, I., Steinbeck, K., Taffe, J., Rice, L., Horstead, S., Rogers, N., Hodge, M., Guastella, A. (2014). A Double-Blind Randomized Controlled Trial of Oxytocin Nasal Spray in Prader Willi Syndrome. American Journal of Medical Genetics. Part A, 164(9), 2232-2239. [More Information]
  • Guastella, A., Gray, K., Rinehart, N., Alvarez, G., Tonge, B., Hickie, I., Keating, C., Cacciotti-Saija, C., Einfeld, S. (2014). The effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: a randomized controlled trial. Journal of Child Psychology and Psychiatry, Early online. [More Information]

2013

  • Carson, D., Guastella, A., Taylor, E., McGregor, I. (2013). A brief history of oxytocin and its role in modulating psychostimulant effects. Journal of Psychopharmacology, 27(3), 231-247. [More Information]
  • Quintana, D., McGregor, I., Guastella, A., Malhi, G., Kemp, A. (2013). A Meta-Analysis on the Impact of Alcohol Dependence on Short-Term Resting-State Heart Rate Variability: Implications for Cardiovascular Risk. Alcoholism: Clinical and Experimental Research, 37(S1), E23-E29. [More Information]
  • Quintana, D., Kemp, A., Alvares, G., Guastella, A. (2013). A role for autonomic cardiac control in the effects of oxytocin on social behavior and psychiatric illness. Frontiers in Neuroscience, 7(April 2013), 1-9. [More Information]
  • Hickie, I., Scott, E., Hermens, D., Naismith, S., Guastella, A., Kaur, M., Sidis, A., Whitwell, B., Glozier, N., Davenport, T., et al (2013). Applying clinical staging to young people who present for mental health care. Early Intervention in Psychiatry, 7(1), 31-43. [More Information]
  • Clarke, P., MacLeod, C., Guastella, A. (2013). Assessing the role of spatial engagement and disengagement of attention in anxiety-linked attentional bias: a critique of current paradigms and suggestions for future research directions. Anxiety Stress and Coping, 26(1), 1-19. [More Information]
  • Hickie, I., Scott, J., Hermens, D., Scott, E., Naismith, S., Guastella, A., Glozier, N., McGorry, P. (2013). Clinical classification in mental health at the cross-roads: which direction next? BMC Medicine, 11(1), 1-14. [More Information]
  • Wudarczyk, O., Earp, B., Guastella, A., Savulescu, J. (2013). Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations. Current Opinion in Psychiatry, 26(5), 474-484. [More Information]
  • Scott, E., Hermens, D., Naismith, S., Guastella, A., De Regt, T., White, D., Lagopoulos, J., Hickie, I. (2013). Distinguishing young people with emerging bipolar disorders from those with unipolar depression. Journal of Affective Disorders, 144(3), 208-215. [More Information]
  • Scott, E., Hermens, D., Naismith, S., Guastella, A., White, D., Whitwell, B., Lagopoulos, J., Scott, J., Hickie, I. (2013). Distress and disability in young adults presenting to clinical services with mood disorders. International Journal of Bipolar Disorders, 1, 1-8. [More Information]
  • McCade, D., Savage, G., Guastella, A., Lewis, S., Naismith, S. (2013). Emotion Recognition Deficits Exist in Mild Cognitive Impairment, But Only in the Amnestic Subtype. Psychology and Aging, 28(3), 840-852. [More Information]
  • McCade, D., Savage, G., Guastella, A., Hickie, I., Lewis, S., Naismith, S. (2013). Emotion Recognition in Mild Cognitive Impairment: Relationship to Psychosocial Disability and Caregiver Burden. Journal of Geriatric Psychiatry and Neurology, 26(3), 165-173. [More Information]
  • Hickie, I., Hermens, D., Naismith, S., Guastella, A., Glozier, N., Scott, J., Scott, E. (2013). Evaluating differential developmental trajectories to adolescent-onset mood and psychotic disorders. BMC Psychiatry, 13(1), 1-11. [More Information]
  • Liu, J., Guastella, A., Dadds, M. (2013). Exploring the role of intra-nasal oxytocin on the partner preference effect in humans. Psychoneuroendocrinology, 38(4), 587-591. [More Information]
  • Quintana, D., Guastella, A., McGregor, I., Hickie, I., Kemp, A. (2013). Heart rate variability predicts alcohol craving in alcohol dependent outpatients: Further evidence for HRV as a psychophysiological marker of self-regulation. Drug and Alcohol Dependence, 132(1-2), 395-398. [More Information]
  • Quintana, D., Guastella, A., McGregor, I., Hickie, I., Kemp, A. (2013). Moderate alcohol intake is related to increased heart rate variability in young adults: Implications for health and well-being. Psychophysiology, 50(12), 1202-1208. [More Information]
  • Hermens, D., Naismith, S., Lagopoulos, J., Lee, C., Guastella, A., Scott, E., Hickie, I. (2013). Neuropsychological profile according to the clinical stage of young persons presenting for mental health care. BMC Psychology, 1, 1-9. [More Information]
  • Guastella, A., Hickie, I., McGuinness, M., Otis, M., Woods, E., Disinger, H., Chan, H., Chen, T., Banati, R. (2013). Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research. Psychoneuroendocrinology, 38(5), 612-625. [More Information]
  • Alvares, G., Quintana, D., Kemp, A., van Zwieten, A., Balleine, B., Hickie, I., Guastella, A. (2013). Reduced heart rate variability in social anxiety disorder: associations with gender and symptom severity. PLoS One, 8(7), 1-8. [More Information]
  • van Zwieten, A., Meyer, J., Hermens, D., Hickie, I., Hawes, D., Glozier, N., Naismith, S., Scott, E., Lee, R., Guastella, A. (2013). Social cognition deficits and psychopathic traits in young people seeking mental health treatment. PLoS One, 8(7), 1-9. [More Information]
  • Guastella, A., Hermens, D., van Zwieten, A., Naismith, S., Lee, R., Cacciotti-Saija, C., Scott, E., Hickie, I. (2013). Social cognitive performance as a marker of positive psychotic symptoms in young people seeking help for mental health problems. Schizophrenia Research, 149(1-3), 77-82. [More Information]
  • Shahrestani, S., Kemp, A., Guastella, A. (2013). The Impact of a Single Administration of Intranasal Oxytocin on the Recognition of Basic Emotions in Humans: A Meta-Analysis. Neuropsychopharmacology, 38(10), 1929-1936. [More Information]
  • Guastella, A., Alvares, G., Hickie, I., Chan, H., Chen, T., Banati, R. (2013). Unitary hormonal models, peripheral markers, and evaluation of response to drug: A response to Weisman and Feldman. Psychoneuroendocrinology, 38, 627-628. [More Information]

2012

  • Lowe (nee Thompson), R., Guastella, A., Chen, N., Menzies, R., Packman, A., O'Brian, S., Onslow, M. (2012). Avoidance of eye gaze by adults who stutter. Journal of Fluency Disorders, 37(4), 263-274. [More Information]
  • Chen, N., Clarke, P., MacLeod, C., Guastella, A. (2012). Biased Attentional Processing of Positive Stimuli in Social Anxiety Disorder: An Eye Movement Study. Cognitive Behaviour Therapy, 41(2), 96-107. [More Information]
  • Clarke, P., Hickie, I., Scott, E., Guastella, A. (2012). Clinical staging model applied to young people presenting with social anxiety. Early Intervention in Psychiatry, 6(3), 256-264. [More Information]
  • Liu, J., Guastella, A., Dadds, M. (2012). Effects of oxytocin on human social approach measured using intimacy equilibriums. Hormones and Behavior, 62(5), 585-591. [More Information]
  • Quintana, D., Guastella, A., Outhred, T., Hickie, I., Kemp, A. (2012). Heart Rate Variability is Associated With Emotion Recognition: Direct Evidence for a Relationship Between the Autonomic Nervous System and Social Cognition. International Journal of Psychophysiology, 86(2), 168-172. [More Information]
  • Bryant, R., Hung, L., Guastella, A., Mitchell, P. (2012). Oxytocin as a moderator of hypnotizability. Psychoneuroendocrinology, 37(1), 162-166. [More Information]
  • Kemp, A., Quintana, D., Kuhnert, R., Griffiths, K., Hickie, I., Guastella, A. (2012). Oxytocin increases heart rate variability in humans at rest: implications for social approach-related motivation and capacity for social engagement. PLoS One, 7(8), 1-6. [More Information]
  • Alvares, G., Chen, N., Balleine, B., Hickie, I., Guastella, A. (2012). Oxytocin selectively moderates negative cognitive appraisals in high trait anxious males. Psychoneuroendocrinology, 37(12), 2022-2031. [More Information]
  • Clarke, P., Chen, N., Guastella, A. (2012). Prepared for the Best: Readiness To Modify Attentional Processing and Reduction in Anxiety Vulnerability in Response to Therapy. Emotion, 12(3), 487-494. [More Information]
  • Scott, E., Hermens, D., Glozier, N., Naismith, S., Guastella, A., Hickie, I. (2012). Targeted primary care-based mental health services for young Australians. Medical Journal of Australia, 196(2), 136-140. [More Information]
  • Scott, E., Hermens, D., Naismith, S., White, D., Whitwell, B., Guastella, A., Glozier, N., Hickie, I. (2012). Thoughts of death or suicidal ideation are common in young people aged 12 to 30 years presenting for mental health care. BMC Psychiatry, 12(December 2012), 1-6. [More Information]

2011

  • Guastella, A., Kenyon, A., Unkelbach, C., Alvares, G., Hickie, I. (2011). Arginine Vasopressin selectively enhances recognition of sexual cues in male humans. Psychoneuroendocrinology, 36(2), 294-297. [More Information]
  • Kemp, A., Guastella, A. (2011). The Role of Oxytocin in Human Affect: A Novel Hypothesis. Current Directions in Psychological Science, 20(4), 222-231. [More Information]
  • Kemp, A., Guastella, A. (2011). The Role of Oxytocin in Human Affect: A Novel Hypothesis. Current Directions in Psychological Science, 20(4), 222-231. [More Information]

2010

  • Alvares, G., Hickie, I., Guastella, A. (2010). Acute effects of intranasal oxytocin on subjective and behavioral responses to social rejection. Experimental and Clinical Psychopharmacology, 18(4), 316-321. [More Information]
  • Guastella, A., Kenyon, A., Alvares, G., Carson, D., Hickie, I. (2010). Intranasal Arginine Vasopressin Enhances the Encoding of Happy and Angry Faces in Humans. Biological Psychiatry, 67(12), 1220-1222. [More Information]
  • Guastella, A., Einfeld, S., Gray, K., Rinehart, N., Tonge, B., Lambert, T., Hickie, I. (2010). Intranasal Oxytocin Improves Emotion Recognition in Youth with Autism Spectrum Disorders. Biological Psychiatry, 67, 692-694. [More Information]
  • Carson, D., Cornish, J., Guastella, A., Hunt, G., McGregor, I. (2010). Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats. Neuropharmacology, 58(1), 38-43. [More Information]
  • Kemp, A., Guastella, A. (2010). Oxytocin: Prosocial Behavior, Social Salience, or Approach-Related Behavior? Biological Psychiatry, 67(6), e33-e34. [More Information]
  • Christensen, H., Guastella, A., Mackinnon, A., Griffiths, K., Eagleson, C., Batterham, P., Kalia, K., Kenardy,, J., Bennett, K., Hickie, I. (2010). Protocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder. Trials, 11, 48-1-48-8. [More Information]
  • Carson, D., Hunt, G., Guastella, A., Barber, L., Cornish, J., Arnold, J., Boucher, A., McGregor, I. (2010). Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in the hypothalamus. Addiction Biology, 15(4), 448-463. [More Information]

2009

  • Guastella, A., Howard, A., Dadds, M., Mitchell, P., Carson, D. (2009). A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder. Psychoneuroendocrinology, 34(6), 917-923. [More Information]
  • Guastella, A., Carson, D., Dadds, M., Mitchell, P., Cox, R. (2009). Does oxytocin influence the early detection of angry and happy faces? Psychoneuroendocrinology, 34, 220-225. [More Information]
  • Guastella, A., Dadds, M. (2009). Sequential growth in cognitive-behavioral emotion-processing: A laboratory study. Cognitive Therapy and Research, 33(4), 368-374.

2008

  • Guastella, A., Richardson, R., Lovibond, P., Rapee, R., Gaston, J., Mitchell, P., Dadds, M. (2008). A Randomized Controlled Trial of D-Cycloserine Enhancement of Exposure Therapy for Social Anxiety Disorder. Biological Psychiatry, 63(6), 544-549. [More Information]
  • Guastella, A., Dadds, M. (2008). Cognitive-behavioural emotion writing tasks: A controlled trial of multiple processes. Journal of Behavior Therapy and Experimental Psychiatry, 39(4), 558-566. [More Information]
  • Guastella, A., Mitchell, P., Matthews, F. (2008). Oxytocin Enhances the Encoding of Positive Social Memories in Humans. Biological Psychiatry, 64(6), 256-258. [More Information]
  • Guastella, A., Mitchell, P., Dadds, M. (2008). Oxytocin Increases Gaze to the Eye Region of Human Faces. Biological Psychiatry, 63(1), 3-5. [More Information]
  • Unkelbach, C., Guastella, A., Forgas, J. (2008). Oxytocin selectively facilitates recognition of positive sex and relationship words. Psychological Science, 19(11), 1092-1094. [More Information]
  • Dadds, M., El Masry, Y., Wimalaweera, S., Guastella, A. (2008). Reduced Eye Gaze Explains "Fear Blindness" in Childhood Psychopathic Traits. Journal of the American Academy of Child and Adolescent Psychiatry, 47(4), 455-463. [More Information]

2007

  • Guastella, A., Dadds, M., Lovibond, P., Mitchell, P., Richardson, R. (2007). A randomized controlled trial of the effect of D-cycloserine on exposure therapy for spider fear. Journal of Psychiatric Research, 41(6), 466-471. [More Information]
  • Guastella, A., Lovibond, P., Dadds, M., Mitchell, P., Richardson, R. (2007). A randomized controlled trial of the effect of D-cycloserine on extinction and fear conditioning in humans. Behaviour Research and Therapy, 45(4), 663-672. [More Information]
  • Guastella, A., Moulds, M. (2007). The impact of rumination on sleep quality following a stressful life event. Personality and Individual Differences, 42(6), 1151-1162.

2006

  • Guastella, A., Dadds, M. (2006). Cognitive-Behavioral Models of Emotional Writing: A Validation Study. Cognitive Therapy and Research, 30(3), 397-414. [More Information]

2004

  • Roth, J., Dadds, M., McAloon, J., Guastella, A., Weems, C. (2004). Prevalence and Prediction of Disorders in Early Childhood: A Community Study. Behaviour Change, 21(4), 215-228.

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