Dr Andrew Hoy
F13 - Anderson Stuart Building
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Dr Hoy is Head of the Lipid Metabolism Laboratory in the Discipline of Physiology SoMS and Bosch Institute as well as an Honorary Associate position with the Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders. He received his PhD training at the Garvan Institute of Medical Research within the Diabetes and Obesity Research Program. Following this he did his Post-Doctoral training in the laboratory of Prof Matthew Watt at Monash University, as a NHMRC Biomedical Australia training Fellow,which has lead to his current research interest in lipid metabolism and how it is perturbed in Obesity, Diabetes and Cancer.
Dr Hoy is currently an active member of Australian Diabetes Society (since 2006), Australian Physiological Society (since 2001), Australian Society of Medical Research (since 2007), and American Society for Biochemistry and Molecular Biology (since 2011).[Hide detail]
Research conducted by my laboratory is focused on the regulation of lipid metabolism, predominantly fatty acid storage and utilisation, and how this may be perturbed in chronic disease states such as cancer, obesity and insulin resistance. For example, investigations are underway to understand the relationship between lipid and glucose metabolism and insulin action. A role for dysregulation of lipid metabolism, which results in accumulation metabolically active lipid intermediates, has been shown to interfere with insulin signalling. Investigations into the relationship between the main site of fatty acid storage, the lipid droplet, and the mitochondria and how this maybe hormonally regulating are ongoing. Finally, understanding the potential role for altered fatty acid metabolism in cancer is another stream of research.
Current Laboratory Members:
Miss Seher Balaban - PhD Student
Mr Harrison Shtein -MPhil Student
Mr Tim Nguyen -MPhil Student
Miss Lisa Lee - BSc Hons Student
Mr Mark Schreuder - visiting MSc Student (University of Utrecht)