Dr Amanda Brandon

Postdoctoral Research Associate
Pathology: School Medical Sciences

Member of the Charles Perkins Centre


Map

Selected grants

2017

  • Can enhancing futile cycles combat obesity related insulin resistance?; Brandon A, Cooney G; Diabetes Australia/Research Grant.

Selected publications

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Journals

  • Turner, N., Lim, X., Toop, H., Osborne, B., Brandon, A., Taylor, E., Fiveash, C., Govindaraju, H., Teo, J., McEwen, H., Couttas, T., Cooney, G., Don, A., et al (2018). A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nature Communications, 9(1). [More Information]
  • Holt, L., Brandon, A., Small, L., Suryana, E., Preston, E., Wilks, D., Mokbel, N., Coles, C., White, J., Turner, N., Cooney, G., et al (2018). Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice. Endocrinology, 159(3), 1339-1351. [More Information]
  • Small, L., Brandon, A., Quek, L., Krycer, J., James, D., Turner, N., Cooney, G. (2018). Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake. American Journal of Physiology - Endocrinology and Metabolism, 315(2), E258-E266. [More Information]
  • Bakshi, I., Suryana, E., Small, L., Quek, L., Brandon, A., Turner, N., Cooney, G. (2018). Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle. Journal of Endocrinology, 237(2), 101-111. [More Information]
  • Bakshi, I., Brown, S., Brandon, A., Suryana, E., Mitchell, T., Turner, N., Cooney, G. (2018). Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats. Scientific Reports, 8(1), 1-12. [More Information]
  • Small, L., Brandon, A., Turner, N., Cooney, G. (2018). Modeling insulin resistance in rodents by alterations in diet: what have high-fat and high-calorie diets revealed? American Journal of Physiology - Endocrinology and Metabolism, 314(3), E251-E265. [More Information]
  • Small, L., Brandon, A., Turner, N., Cooney, G. (2018). Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed? American Journal of Physiology - Endocrinology and Metabolism, 314(3), E251-E265. [More Information]
  • Loh, K., Zhang, L., Brandon, A., Wang, K., Begg, D., Qi, Y., Fu, M., Kulkarni, R., Teo, J., Baldock, P., Cooney, G., Neely, G., et al (2017). Corrigendum to Insulin controls food intake and energy balance via NPY neurons" [Mol Metabol 6 (2017) 574-584]". Molecular Metabolism, 6(11), 1562. [More Information]
  • Nagarajan, S., Brandon, A., McKenna, J., Shtein, H., Nguyen, T., Suryana, E., Poronnik, P., Cooney, G., Saunders, D., Hoy, A. (2017). Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver. PloS One, 12(3), 1-14. [More Information]
  • Loh, K., Zhang, L., Brandon, A., Wang, K., Begg, D., Qi, Y., Fu, M., Kulkarni, R., Cooney, G., Teo, J., Neely, G., et al (2017). Insulin controls food intake and energy balance via NPY neurons. Molecular Metabolism, 6(6), 574-584. [More Information]
  • Brandon, A., Stuart, E., Leslie, S., Hoehn, K., James, D., Kraegen, E., Turner, N., Cooney, G. (2016). Minimal impact of age and housing temperature on the metabolic phenotype of Acc2K/K mice. Journal of Endocrinology, 228(3), 127-134. [More Information]
  • Coughlan, K., Balon, T., Valentine, R., Petrocelli, R., Schultz, V., Brandon, A., Cooney, G., Kraegen, E., Ruderman, N., Saha, A. (2015). Nutrient excess and AMPK downregulation in incubated skeletal muscle and muscle of glucose infused rats. PloS One, 10(5), 1-17. [More Information]
  • Brandon, A., Tid-Ang, J., Wright, L., Stuart, E., Suryana, E., Bentley, N., Turner, N., Cooney, G., Ruderman, N., Kraegen, E. (2015). Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance. PloS One, 10(3), 1-12. [More Information]
  • Hocking, S., Stewart, R., Brandon, A., Suryana, E., Stuart, E., Baldwin, E., Kolumam, G., Modrusan, Z., Junutula, J., Gunton, J., James, D., et al (2015). Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice. Diabetologia, 58(7), 1587-1600. [More Information]
  • Stoeckli, J., Meoli, C., Hoffman, N., Fazakerley, D., Pant, H., Cleasby, M., Ma, X., Kleinert, M., Brandon, A., Lopez, J., James, D., et al (2015). The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle. Diabetes, 64(6), 1914-1922. [More Information]
  • Boden, M., Brandon, A., Tid-Ang, J., Preston, E., Wilks, D., Stuart, E., Cleasby, M., Turner, N., Cooney, G., Kraegen, E. (2012). Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle. American Journal of Physiology - Endocrinology and Metabolism, 303(6), E798-E805. [More Information]
  • Wright, L., Brandon, A., Hoy, A., Forsberg, G., Lelliott, C., Reznick, J., Löfgren, L., Oscarsson, J., Strömstedt, M., Cooney, G., et al (2011). Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1(beta) involves reductions in long-chain acyl-CoA levels and oxidative stress. Diabetologia, 54(6), 1417-1426. [More Information]
  • Saha, A., Xu, X., Balon, T., Brandon, A., Kraegen, E., Ruderman, N. (2011). Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation? Cell Cycle, 10(20), 3447-3451. [More Information]
  • Brandon, A., Boyce, A., Lumbers, E., Kumarasamy, V., Gibson, K. (2011). Programming of the renin response to haemorrhage by mild maternal renal impairment in sheep. Clinical and Experimental Pharmacology and Physiology, 38(2), 102-108. [More Information]
  • Brandon, A., Hoy, A., Wright, L., Turner, N., Hegarty, B., Iseli, T., Xu, J., Cooney, G., Saha, A., Ruderman, N., et al (2011). The evolution of insulin resistance in muscle of the glucose infused rat. Archives of Biochemistry and Biophysics, 509(2), 133-141. [More Information]
  • Hoy, A., Brandon, A., Turner, N., Watt, M., Bruce, C., Cooney, G., Kraegen, E. (2009). Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation. American Journal of Physiology - Endocrinology and Metabolism, 297(1), E67-E75. [More Information]

2018

  • Turner, N., Lim, X., Toop, H., Osborne, B., Brandon, A., Taylor, E., Fiveash, C., Govindaraju, H., Teo, J., McEwen, H., Couttas, T., Cooney, G., Don, A., et al (2018). A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nature Communications, 9(1). [More Information]
  • Holt, L., Brandon, A., Small, L., Suryana, E., Preston, E., Wilks, D., Mokbel, N., Coles, C., White, J., Turner, N., Cooney, G., et al (2018). Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice. Endocrinology, 159(3), 1339-1351. [More Information]
  • Small, L., Brandon, A., Quek, L., Krycer, J., James, D., Turner, N., Cooney, G. (2018). Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake. American Journal of Physiology - Endocrinology and Metabolism, 315(2), E258-E266. [More Information]
  • Bakshi, I., Suryana, E., Small, L., Quek, L., Brandon, A., Turner, N., Cooney, G. (2018). Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle. Journal of Endocrinology, 237(2), 101-111. [More Information]
  • Bakshi, I., Brown, S., Brandon, A., Suryana, E., Mitchell, T., Turner, N., Cooney, G. (2018). Increasing Acyl CoA thioesterase activity alters phospholipid profile without effect on insulin action in skeletal muscle of rats. Scientific Reports, 8(1), 1-12. [More Information]
  • Small, L., Brandon, A., Turner, N., Cooney, G. (2018). Modeling insulin resistance in rodents by alterations in diet: what have high-fat and high-calorie diets revealed? American Journal of Physiology - Endocrinology and Metabolism, 314(3), E251-E265. [More Information]
  • Small, L., Brandon, A., Turner, N., Cooney, G. (2018). Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed? American Journal of Physiology - Endocrinology and Metabolism, 314(3), E251-E265. [More Information]

2017

  • Loh, K., Zhang, L., Brandon, A., Wang, K., Begg, D., Qi, Y., Fu, M., Kulkarni, R., Teo, J., Baldock, P., Cooney, G., Neely, G., et al (2017). Corrigendum to Insulin controls food intake and energy balance via NPY neurons" [Mol Metabol 6 (2017) 574-584]". Molecular Metabolism, 6(11), 1562. [More Information]
  • Nagarajan, S., Brandon, A., McKenna, J., Shtein, H., Nguyen, T., Suryana, E., Poronnik, P., Cooney, G., Saunders, D., Hoy, A. (2017). Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver. PloS One, 12(3), 1-14. [More Information]
  • Loh, K., Zhang, L., Brandon, A., Wang, K., Begg, D., Qi, Y., Fu, M., Kulkarni, R., Cooney, G., Teo, J., Neely, G., et al (2017). Insulin controls food intake and energy balance via NPY neurons. Molecular Metabolism, 6(6), 574-584. [More Information]

2016

  • Brandon, A., Stuart, E., Leslie, S., Hoehn, K., James, D., Kraegen, E., Turner, N., Cooney, G. (2016). Minimal impact of age and housing temperature on the metabolic phenotype of Acc2K/K mice. Journal of Endocrinology, 228(3), 127-134. [More Information]

2015

  • Coughlan, K., Balon, T., Valentine, R., Petrocelli, R., Schultz, V., Brandon, A., Cooney, G., Kraegen, E., Ruderman, N., Saha, A. (2015). Nutrient excess and AMPK downregulation in incubated skeletal muscle and muscle of glucose infused rats. PloS One, 10(5), 1-17. [More Information]
  • Brandon, A., Tid-Ang, J., Wright, L., Stuart, E., Suryana, E., Bentley, N., Turner, N., Cooney, G., Ruderman, N., Kraegen, E. (2015). Overexpression of SIRT1 in rat skeletal muscle does not alter glucose induced insulin resistance. PloS One, 10(3), 1-12. [More Information]
  • Hocking, S., Stewart, R., Brandon, A., Suryana, E., Stuart, E., Baldwin, E., Kolumam, G., Modrusan, Z., Junutula, J., Gunton, J., James, D., et al (2015). Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice. Diabetologia, 58(7), 1587-1600. [More Information]
  • Stoeckli, J., Meoli, C., Hoffman, N., Fazakerley, D., Pant, H., Cleasby, M., Ma, X., Kleinert, M., Brandon, A., Lopez, J., James, D., et al (2015). The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle. Diabetes, 64(6), 1914-1922. [More Information]

2012

  • Boden, M., Brandon, A., Tid-Ang, J., Preston, E., Wilks, D., Stuart, E., Cleasby, M., Turner, N., Cooney, G., Kraegen, E. (2012). Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle. American Journal of Physiology - Endocrinology and Metabolism, 303(6), E798-E805. [More Information]

2011

  • Wright, L., Brandon, A., Hoy, A., Forsberg, G., Lelliott, C., Reznick, J., Löfgren, L., Oscarsson, J., Strömstedt, M., Cooney, G., et al (2011). Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1(beta) involves reductions in long-chain acyl-CoA levels and oxidative stress. Diabetologia, 54(6), 1417-1426. [More Information]
  • Saha, A., Xu, X., Balon, T., Brandon, A., Kraegen, E., Ruderman, N. (2011). Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation? Cell Cycle, 10(20), 3447-3451. [More Information]
  • Brandon, A., Boyce, A., Lumbers, E., Kumarasamy, V., Gibson, K. (2011). Programming of the renin response to haemorrhage by mild maternal renal impairment in sheep. Clinical and Experimental Pharmacology and Physiology, 38(2), 102-108. [More Information]
  • Brandon, A., Hoy, A., Wright, L., Turner, N., Hegarty, B., Iseli, T., Xu, J., Cooney, G., Saha, A., Ruderman, N., et al (2011). The evolution of insulin resistance in muscle of the glucose infused rat. Archives of Biochemistry and Biophysics, 509(2), 133-141. [More Information]

2009

  • Hoy, A., Brandon, A., Turner, N., Watt, M., Bruce, C., Cooney, G., Kraegen, E. (2009). Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation. American Journal of Physiology - Endocrinology and Metabolism, 297(1), E67-E75. [More Information]

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