Dr Susie Mihailidou

Clinical Senior Lecturer
Medicine, Northern Clinical School

Telephone +61 2 9926 4956
Fax +61 2 9926 5144

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Research interests

cardiovascular regulation of steroid hormones and sex differences in response to ischemia-reperfusion during diabetes - both Type I and II and translating these findings to patient management;

blood pressure regulation and measurement for hypertension management and during bereavement and sleep apnoea

Teaching and supervision

blood pressure regulation and measurement; ambulatory blood pressure

International links

United States

(Division of Endocrinology, G.V. (Sonny) Montgomery VA Medical Center and University of Mississippi Medical Center, Jackson, MS, USA. ) Sharing research materials and complemetary studies

Selected grants

2006

  • Antagonist and Agonist effects of glucocorticoids on cardiovascular mineralocorticoid receptors; Mihailidou A; National Heart Foundation/Grants-in-Aid.
  • Antagonist and Agonist effects of glucocorticoids on cardiovascular mineralocorticoid receptors; Mihailidou A; National Heart Foundation/Grants-in-Aid.
  • University of Sydney - Bridging Support Grant; Mihailidou A; University of Sydney/Bridging Support.

Selected publications

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Book Chapters

  • Mihailidou, A., Ritchie, R., Ashton, A. (2013). Sex Differences in Sudden Cardiac Death. In David Gaze (Eds.), Ischemic Heart Disease, (pp. 61-75). Croatia: InTech Publishers.
  • Mihailidou, A. (2012). Ischemic Heart Disease, Diabetes and Mineralocorticoid Receptors. In Umashankar Lakshmanadoss (Eds.), Novel Strategies in Ischemic Heart Disease, (pp. 287-298). Croatia: InTech Publishers.

Journals

  • Ohkubo, T., Mihailidou, A. (2014). Is there a role for day-to-day home blood pressure variability in guiding management of hypertension? Clinical and Experimental Pharmacology and Physiology, 41(1), 54-57. [More Information]
  • Le, T., Ashton, A., Mardini, M., Stanton, P., Funder, J., Handelsman, D., Mihailidou, A. (2014). Role of Androgens in Sex Differences in Cardiac Damage During Myocardial Infarction. Endocrinology, 155(2), 568-575. [More Information]
  • Young, M., Fuller, P., Stowasser, M., Mihailidou, A. (2013). Frontiers in Research Review: Aldosterone and Salt: Heart and Kidney. Introduction. Clinical and Experimental Pharmacology and Physiology, 40(12), 872-875. [More Information]
  • Phillips, C., Grunstein, R., Darendeliler, M., Mihailidou, A., Srinivasan, V., Yee, B., Marks, G., Cistulli, P. (2013). Health Outcomes of Continuous Positive Airway Pressure versus Oral Appliance Treatment for Obstructive Sleep Apnea: A Randomised Controlled Trial. American Journal of Respiratory and Critical Care Medicine, 187(8), 879-887. [More Information]
  • Leung, M., Wong, V., Heritier, S., Mihailidou, A., Leung, D. (2013). Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy. Cardiovascular Diabetology, 12(October 2013), 1-10. [More Information]
  • Mihailidou, A. (2012). Aldosterone in Heart Disease. Current Hypertension Reports, 14(2), 125-129. [More Information]
  • Head, G., McGrath, B., Mihailidou, A., Nelson, M., Schlaich, M., Stowasser, M., Mangoni, A., Cowley, D., Brown, M., Ruta, L., et al (2012). Ambulatory blood pressure monitoring in Australia: 2011 consensus position statement. Journal of Hypertension, 30(2), 253-266. [More Information]
  • Buckley, T., Stannard, A., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2012). Effect of Early Bereavement on Heart Rate and Heart Rate Variability. The American Journal of Cardiology, 110(9), 1378-1383. [More Information]
  • Buckley, T., Morel-Kopp, M., Ward, C., Bartrop, R., McKinley, S., Mihailidou, A., Spinaze, M., Chen, W., Tofler, G. (2012). Inflammatory and thrombotic changes in early bereavement: A prospective evaluation. European Journal of Preventive Cardiology, 19(5), 1145-1152. [More Information]
  • Le, T., Mardini, M., Howell, V., Funder, J., Ashton, A., Mihailidou, A. (2012). Low-dose spironolactone prevents apoptosis repressor with caspase recruitment domain degradation during myocardial infarction. Hypertension, 59(6), 1164-1169. [More Information]
  • Head, G., McGrath, B., Mihailidou, A., Nelson, M., Schlaich, M., Stowasser, M., Mangoni, A., Cowley, D., Wilson, A. (2011). Ambulatory blood pressure monitoring. Australian Family Physician, 40(11), 877-880.
  • Buckley, T., Mihailidou, A., Bartrop, R., McKinley, S., Ward, C., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Haemodynamic Changes During Early Bereavement: Potential Contribution to Increased Cardiovascular Risk. Heart, Lung and Circulation, 20(2), 91-98. [More Information]
  • Wong, V., Mardini, M., Cheung, N., Mihailidou, A. (2011). High-dose insulin in experimental myocardial infarction in rabbits: protection against effects of hyperglycaemia. Journal of Diabetes and Its Complications, 25(2), 122-128. [More Information]
  • Mihailidou, A., Buckley, T., McKinley, S., Ward, C., Bartrop, R., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Increased blood pressure variability during early bereavement. Circulation (Baltimore), 124(S1), A17769.
  • Head, G., Mihailidou, A., Duggan, K., Beilin, L., Berry, N., Brown, M., Bune, A., Cowley, D., Chalmers, J., Howe, P., et al (2010). Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study. BMJ: British Medical Journal, 340(c1104), 1-8. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2010). Early bereavement is associated with increased heart rate and reduced heart rate variability. Circulation, 122, A14660.
  • Funder, J., Mihailidou, A. (2009). Aldosterone and mineralocorticoid receptors: Clinical studies and basic biology. Molecular And Cellular Endocrinology, 301(1-2), 2-6. [More Information]
  • Buckley, T., Mihailidou, A., Bartrop, R., Ward, C., Morel-Kopp, M., McKinley, S., Spinaze, M., Tofler, G. (2009). An evaluation of psychological and physiological determinants of cardiovascular risk in early bereavement. Heart, Lung and Circulation, 18(3), S7.
  • Mihailidou, A., Le, T., Mardini, M., Funder, J. (2009). Glucocorticoids Activate Cardiac Mineralocorticoid Receptors During Experimental Myocardial Infarction. Hypertension, 54(6), 1306-1312. [More Information]
  • Mihailidou, A., Buckley, T., Spinaze, M., Roche, D., Bramwell, M., McKinley, S., Morel-Kopp, M., Ward, C., Bartrop, R., Tofler, G. (2009). Increased blood pressure load during bereavement: Potential mechanism for increased cardiovascular risk. Hypertension.
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Bramwell, M., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Hocking, B., Tennant, C., Tofler, G., et al (2009). Prospective study of early bereavement on psychological and behavioural cardiac risk factors. Internal Medicine Journal, 39(6), 370-378. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Goldstone, K., Ward, C., Bramwell, M., Hocking, B., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tennant, C., Tofler, G. (2007). An evaluation of psychological and behavioural factors during bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tofler, G., et al (2007). Inflammatory and thrombotic changes in bereavement in bereavement: A potential mechanism of increased cardiovascular risk. Circulation, 116(16), 844.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tennant, C., Tofler, G. (2007). Inflammatory, thrombotic and haemodynamic changes in bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Mihailidou, A. (2006). Nongenomic actions of aldosterone: Physiological or pathophysiological role? Steroids. [More Information]
  • Mihailidou, A. (2005). Nongenomic cardiovascular actions of aldosterone: a receptor for all seasons? Endocrinology, 146(3), 971-972. [More Information]
  • Mihailidou, A., Funder, J. (2005). Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system. Steroids, 70(5-7), 347-351. [More Information]
  • Mihailidou, A., Mardini, M., Funder, J. (2004). Rapid, Nongenomic Effects Of Aldosterone In The Heart Mediated By Epsilon Protein Kinase C. Endocrinology, 145(2), 773-780.
  • Mardini, M., Mihailidou, A., Wong, A., Rasmussen, H. (2001). Cyclosporine and FK506 differentially regulate the sarcolemmal Na+-K+ pump. Journal of Pharmacology and Experimental Therapeutics, 47, 132-140.
  • Mardini, M., Rasmussen, H., Mihailidou, A., Wong, A. (2001). Cyclosporine and FK506 differentially regulate the sarcolemmal Na+-K+ pump. Journal of Pharmacology and Experimental Therapeutics, 297, 804-810.
  • Mihailidou, A., Bundgaard, H., Mardini, M., Hansen, P., Kjeldsen, H., Rasmussen, H. (2000). Hyperaldosteronemia in rabbits inhibits the cardiac sarcolemmal Na+-K+ pump. Circulation Research, 86, 37-42.

2014

  • Ohkubo, T., Mihailidou, A. (2014). Is there a role for day-to-day home blood pressure variability in guiding management of hypertension? Clinical and Experimental Pharmacology and Physiology, 41(1), 54-57. [More Information]
  • Le, T., Ashton, A., Mardini, M., Stanton, P., Funder, J., Handelsman, D., Mihailidou, A. (2014). Role of Androgens in Sex Differences in Cardiac Damage During Myocardial Infarction. Endocrinology, 155(2), 568-575. [More Information]

2013

  • Young, M., Fuller, P., Stowasser, M., Mihailidou, A. (2013). Frontiers in Research Review: Aldosterone and Salt: Heart and Kidney. Introduction. Clinical and Experimental Pharmacology and Physiology, 40(12), 872-875. [More Information]
  • Phillips, C., Grunstein, R., Darendeliler, M., Mihailidou, A., Srinivasan, V., Yee, B., Marks, G., Cistulli, P. (2013). Health Outcomes of Continuous Positive Airway Pressure versus Oral Appliance Treatment for Obstructive Sleep Apnea: A Randomised Controlled Trial. American Journal of Respiratory and Critical Care Medicine, 187(8), 879-887. [More Information]
  • Leung, M., Wong, V., Heritier, S., Mihailidou, A., Leung, D. (2013). Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy. Cardiovascular Diabetology, 12(October 2013), 1-10. [More Information]
  • Mihailidou, A., Ritchie, R., Ashton, A. (2013). Sex Differences in Sudden Cardiac Death. In David Gaze (Eds.), Ischemic Heart Disease, (pp. 61-75). Croatia: InTech Publishers.

2012

  • Mihailidou, A. (2012). Aldosterone in Heart Disease. Current Hypertension Reports, 14(2), 125-129. [More Information]
  • Head, G., McGrath, B., Mihailidou, A., Nelson, M., Schlaich, M., Stowasser, M., Mangoni, A., Cowley, D., Brown, M., Ruta, L., et al (2012). Ambulatory blood pressure monitoring in Australia: 2011 consensus position statement. Journal of Hypertension, 30(2), 253-266. [More Information]
  • Buckley, T., Stannard, A., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2012). Effect of Early Bereavement on Heart Rate and Heart Rate Variability. The American Journal of Cardiology, 110(9), 1378-1383. [More Information]
  • Buckley, T., Morel-Kopp, M., Ward, C., Bartrop, R., McKinley, S., Mihailidou, A., Spinaze, M., Chen, W., Tofler, G. (2012). Inflammatory and thrombotic changes in early bereavement: A prospective evaluation. European Journal of Preventive Cardiology, 19(5), 1145-1152. [More Information]
  • Mihailidou, A. (2012). Ischemic Heart Disease, Diabetes and Mineralocorticoid Receptors. In Umashankar Lakshmanadoss (Eds.), Novel Strategies in Ischemic Heart Disease, (pp. 287-298). Croatia: InTech Publishers.
  • Le, T., Mardini, M., Howell, V., Funder, J., Ashton, A., Mihailidou, A. (2012). Low-dose spironolactone prevents apoptosis repressor with caspase recruitment domain degradation during myocardial infarction. Hypertension, 59(6), 1164-1169. [More Information]

2011

  • Head, G., McGrath, B., Mihailidou, A., Nelson, M., Schlaich, M., Stowasser, M., Mangoni, A., Cowley, D., Wilson, A. (2011). Ambulatory blood pressure monitoring. Australian Family Physician, 40(11), 877-880.
  • Buckley, T., Mihailidou, A., Bartrop, R., McKinley, S., Ward, C., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Haemodynamic Changes During Early Bereavement: Potential Contribution to Increased Cardiovascular Risk. Heart, Lung and Circulation, 20(2), 91-98. [More Information]
  • Wong, V., Mardini, M., Cheung, N., Mihailidou, A. (2011). High-dose insulin in experimental myocardial infarction in rabbits: protection against effects of hyperglycaemia. Journal of Diabetes and Its Complications, 25(2), 122-128. [More Information]
  • Mihailidou, A., Buckley, T., McKinley, S., Ward, C., Bartrop, R., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Increased blood pressure variability during early bereavement. Circulation (Baltimore), 124(S1), A17769.

2010

  • Head, G., Mihailidou, A., Duggan, K., Beilin, L., Berry, N., Brown, M., Bune, A., Cowley, D., Chalmers, J., Howe, P., et al (2010). Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study. BMJ: British Medical Journal, 340(c1104), 1-8. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2010). Early bereavement is associated with increased heart rate and reduced heart rate variability. Circulation, 122, A14660.

2009

  • Funder, J., Mihailidou, A. (2009). Aldosterone and mineralocorticoid receptors: Clinical studies and basic biology. Molecular And Cellular Endocrinology, 301(1-2), 2-6. [More Information]
  • Buckley, T., Mihailidou, A., Bartrop, R., Ward, C., Morel-Kopp, M., McKinley, S., Spinaze, M., Tofler, G. (2009). An evaluation of psychological and physiological determinants of cardiovascular risk in early bereavement. Heart, Lung and Circulation, 18(3), S7.
  • Mihailidou, A., Le, T., Mardini, M., Funder, J. (2009). Glucocorticoids Activate Cardiac Mineralocorticoid Receptors During Experimental Myocardial Infarction. Hypertension, 54(6), 1306-1312. [More Information]
  • Mihailidou, A., Buckley, T., Spinaze, M., Roche, D., Bramwell, M., McKinley, S., Morel-Kopp, M., Ward, C., Bartrop, R., Tofler, G. (2009). Increased blood pressure load during bereavement: Potential mechanism for increased cardiovascular risk. Hypertension.
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Bramwell, M., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Hocking, B., Tennant, C., Tofler, G., et al (2009). Prospective study of early bereavement on psychological and behavioural cardiac risk factors. Internal Medicine Journal, 39(6), 370-378. [More Information]

2007

  • Buckley, T., Bartrop, R., McKinley, S., Goldstone, K., Ward, C., Bramwell, M., Hocking, B., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tennant, C., Tofler, G. (2007). An evaluation of psychological and behavioural factors during bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tofler, G., et al (2007). Inflammatory and thrombotic changes in bereavement in bereavement: A potential mechanism of increased cardiovascular risk. Circulation, 116(16), 844.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tennant, C., Tofler, G. (2007). Inflammatory, thrombotic and haemodynamic changes in bereavement. Heart, Lung and Circulation, 16(S1), S201.

2006

  • Mihailidou, A. (2006). Nongenomic actions of aldosterone: Physiological or pathophysiological role? Steroids. [More Information]

2005

  • Mihailidou, A. (2005). Nongenomic cardiovascular actions of aldosterone: a receptor for all seasons? Endocrinology, 146(3), 971-972. [More Information]
  • Mihailidou, A., Funder, J. (2005). Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system. Steroids, 70(5-7), 347-351. [More Information]

2004

  • Mihailidou, A., Mardini, M., Funder, J. (2004). Rapid, Nongenomic Effects Of Aldosterone In The Heart Mediated By Epsilon Protein Kinase C. Endocrinology, 145(2), 773-780.

2001

  • Mardini, M., Mihailidou, A., Wong, A., Rasmussen, H. (2001). Cyclosporine and FK506 differentially regulate the sarcolemmal Na+-K+ pump. Journal of Pharmacology and Experimental Therapeutics, 47, 132-140.
  • Mardini, M., Rasmussen, H., Mihailidou, A., Wong, A. (2001). Cyclosporine and FK506 differentially regulate the sarcolemmal Na+-K+ pump. Journal of Pharmacology and Experimental Therapeutics, 297, 804-810.

2000

  • Mihailidou, A., Bundgaard, H., Mardini, M., Hansen, P., Kjeldsen, H., Rasmussen, H. (2000). Hyperaldosteronemia in rabbits inhibits the cardiac sarcolemmal Na+-K+ pump. Circulation Research, 86, 37-42.

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