Dr Andrew Chang

Clinical Senior Lecturer
Clinical Ophthalmology & Eye Health, Central Clinical School

Telephone +61 2 92324800
Fax +61 2 9221 1637

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Current research students

Project title Research student
Utility of macula perimetry in assessment of maculopathy Rashmi NAIR
Treatment resistance in exudative age related macular degeneration Kimberly SPOONER

Selected grants

2001

  • Investigation of indocyanine green dye with the interaction of retinal tissue; Chang A, Zhu M; Eye and Vision Research Institute/Research Grant.
  • Save Sight and Eye Health Institute; Chang A, Billson F, Zhu M; Sydney Eye Hospital Foundation/Research Project Support.

Selected publications

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Journals

  • Broadhead, G., Grigg, J., McCluskey, P., Korsakova, M., Chang, A. (2016). Bevacizumab for choroidal neovascularisation in enhanced S-cone syndrome. Documenta Ophthalmologica, 133(2), 139-143. [More Information]
  • Bahrami, B., Zhu, M., Hong, T., Chang, A. (2016). Diabetic macular oedema: pathophysiology, management challenges and treatment resistance. Diabetologia, 59(8), 1594-1608. [More Information]
  • Broadhead, G., Chang, A., Grigg, J., McCluskey, P. (2016). Efficacy and Safety of Saffron Supplementation: Current Clinical Findings. Critical Reviews in Food Science and Nutrition, Early View. [More Information]
  • Powner, M., Sim, D., Zhu, M., Nobre Cardoso, J., Jones, R., Syed, A., Chang, A., Keane, P., Tufail, A., Egan, C., et al (2016). Evaluation of nonperfused retinal vessels in ischemic retinopathy. Investigative Ophthalmology and Visual Science, 57(11), 5031-5037. [More Information]
  • Chang, A., Broadhead, G., Hong, T., Joachim, N., Syed, A., Schlub, T., Toth, L., Peto, T., Zhu, M. (2016). Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-Related Macular Degeneration: 12-Month Safety and Efficacy Outcomes. Ophthalmic research, 55(2), 84-90. [More Information]
  • Staffieri, S., Rose, L., Chang, A., De Roach, J., McLaren, T., Mackey, D., Hewitt, A., Lamey, T. (2015). Clinical and molecular characterization of females affected by X-linked retinoschisis. Clinical and Experimental Ophthalmology, 43(7), 643-647. [More Information]
  • Broadhead, G., Grigg, J., Chang, A., McCluskey, P. (2015). Dietary modification and supplementation for the treatment of age-related macular degeneration. Nutrition Reviews, 73(7), 448-462. [More Information]
  • Broadhead, G., Chang, A. (2015). Intravitreal aflibercept for choroidal neovascularisation complicating chronic central serous chorioretinopathy. Graefes Archive for Clinical and Experimental Ophthalmology, 253(6), 979-981. [More Information]
  • Zhu, M., Chew, J., Broadhead, G., Luo, K., Joachim, N., Hong, T., Syed, A., Chang, A. (2015). Intravitreal Ranibizumab for neovascular Age-related macular degeneration in clinical practice: five-year treatment outcomes. Graefes Archive for Clinical and Experimental Ophthalmology, 253(8), 1217-1225. [More Information]
  • Broadhead, G., Hong, T., Zhu, M., Li, H., Schlub, T., Wijeyakumar, W., Chang, A. (2015). Response of pigment epithelial detachments to intravitreal aflibercept among patients with treatment-resistant neovascular age-related macular degeneration. Retina: the Journal of Retinal and Vitreous Diseases, 35(5), 975-981. [More Information]
  • Chang, A., Li, H., Broadhead, G., Luo, K., Zhu, M. (2015). Safety and Efficacy of Intravitreal Preservative-Free Triamcinolone Acetonide (Triesence) for Macular Edema. Journal of Ocular Pharmacology and Therapeutics, 31(9), 563-569. [More Information]
  • Chang, A., Hong, T., Ewe, Y., Bahrami, B., Broadhead, G. (2015). The role of aflibercept in the management of diabetic macular edema. Drug Design, Development and Therapy, 9, 4389-4396. [More Information]
  • Broadhead, G., Chang, A. (2014). Acetazolamide for cystoid macular oedema in Bietti crystalline retinal dystrophy. Korean Journal of Ophthalmology, 28(2), 189-191. [More Information]
  • Chang, A., Li, H., Broadhead, G., Hong, T., Schlub, T., Wijeyakumar, W., Zhu, M. (2014). Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-related Macular Degeneration. Ophthalmology, 121(1), 188-192. [More Information]
  • Broadhead, G., Hong, T., Chang, A. (2014). Treating the untreatable patient: Current options for the management of treatment-resistant neovascular age-related macular degeneration. Acta Ophthalmologica, 92(8), 713-723. [More Information]
  • Broadhead, G., Chang, A. (2013). Choroidal neovascularization in acquired partial lipodystrophy. European Journal of Ophthalmology, 23(3), 439-441. [More Information]
  • Wang, Y., Chang, A. (2013). Clinical features and PDT effect of patients with CCSC. Guoji Yanke Zazhi (International Eye Science), 13(3), 522-526. [More Information]
  • Chui, J., Herkes, G., Chang, A. (2013). Management of fingolimod-associated macular edema. JAMA Ophthalmology, 131(5), 694-696. [More Information]
  • Simunovic, M., Rush, R., Hunyor, A., Chang, A. (2012). Endophthalmitis following intravitreal injection versus endophthalmitis following cataract surgery: clinical features, causative organisms and post-treatment outcomes. British Journal of Ophthalmology, 96(6), 862-866. [More Information]
  • Merani, R., Hunyor, A., Playfair, T., Chang, A., Gregory-Roberts, J., Hunyor, A., Azar, D., Cumming, R. (2007). Pars Plana Vitrectomy for the Management of Retained Lens Material After Cataract Surgery. American Journal of Ophthalmology, 144(3), 364-370. [More Information]
  • Chong, C., Chang, A. (2006). Traumatic optic nerve avulsion and central retinal artery occlusion following rugby injury. Clinical and Experimental Ophthalmology, 34(1), 88-89.
  • Jiang, W., Zhong, Z., Henson, J., Neumann, A., Chang, A., Reddel, R. (2005). Suppression of Alternative Lengthening of Telomeres by Sp100-Mediated Sequestration of the MRE11/RAD50/NBS1 Complex. Molecular and Cellular Biology, 25(7), 2708-2721. [More Information]
  • Chang, A., Zhu, M., Billson, F. (2005). The Interaction of Indocyanine Green with Human Retinal Pigment Epithelium. Investigative Ophthalmology and Visual Science, 46(4), 1463-1467. [More Information]
  • Chang, A., Cha, J., Koentgen, F., Reddel, R. (2005). The murine stanniocalcin 1 gene is not essential for growth and development. Molecular and Cellular Biology, 25(23), 10604-10610. [More Information]
  • Wong, J., Sachdev, N., Beaumont, P., Chang, A. (2005). Visual outcomes following vitrectomy and peeling of epiretinal membrane. Clinical and Experimental Ophthalmology, 33(4), 373-378. [More Information]
  • Sirimaharaj, M., Balachandran, C., Chan, W., Hunyor, A., Chang, A., Gregory-Roberts, J., Hunyor, A., Playfair, T. (2005). Vitrectomy with short term postoperative tamponade using perfluorocarbon liquid for giant retinal tears. British Journal of Ophthalmology, 89(9), 1176-1179. [More Information]
  • Chang, A., Raik, E., Marsden, K., Ma, D. (2004). Australasian CD34+ Quality Assurance Program And Rationale For The Clinical Utility Of The Single-Platform Method For CD34+ Cell Enumeration. Cytotherapy, 6(1), 50-61.
  • Chang, A., Zhu, M., Billson, F., Kumar, N., Beaumont, P. (2004). Indocyanine green localisation in surgically excised choroidal neovascular membrane in age-related macular degeneration. British Journal of Ophthalmology, 88(2), 307-309.
  • Chang, A., Guyer, D., Orlock, D., Yannuzzi, L. (2003). Age-dependent variations in the drusen fluorescence on indocyanine green angiography. Clinical and Experimental Ophthalmology, 31(4), 300-304. [More Information]
  • Chang, A., Jellinek, D., Reddel, R. (2003). Mammalian stanniocalcins and cancer. Endocrine-Related Cancer, 10(3), 359-373.

2016

  • Broadhead, G., Grigg, J., McCluskey, P., Korsakova, M., Chang, A. (2016). Bevacizumab for choroidal neovascularisation in enhanced S-cone syndrome. Documenta Ophthalmologica, 133(2), 139-143. [More Information]
  • Bahrami, B., Zhu, M., Hong, T., Chang, A. (2016). Diabetic macular oedema: pathophysiology, management challenges and treatment resistance. Diabetologia, 59(8), 1594-1608. [More Information]
  • Broadhead, G., Chang, A., Grigg, J., McCluskey, P. (2016). Efficacy and Safety of Saffron Supplementation: Current Clinical Findings. Critical Reviews in Food Science and Nutrition, Early View. [More Information]
  • Powner, M., Sim, D., Zhu, M., Nobre Cardoso, J., Jones, R., Syed, A., Chang, A., Keane, P., Tufail, A., Egan, C., et al (2016). Evaluation of nonperfused retinal vessels in ischemic retinopathy. Investigative Ophthalmology and Visual Science, 57(11), 5031-5037. [More Information]
  • Chang, A., Broadhead, G., Hong, T., Joachim, N., Syed, A., Schlub, T., Toth, L., Peto, T., Zhu, M. (2016). Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-Related Macular Degeneration: 12-Month Safety and Efficacy Outcomes. Ophthalmic research, 55(2), 84-90. [More Information]

2015

  • Staffieri, S., Rose, L., Chang, A., De Roach, J., McLaren, T., Mackey, D., Hewitt, A., Lamey, T. (2015). Clinical and molecular characterization of females affected by X-linked retinoschisis. Clinical and Experimental Ophthalmology, 43(7), 643-647. [More Information]
  • Broadhead, G., Grigg, J., Chang, A., McCluskey, P. (2015). Dietary modification and supplementation for the treatment of age-related macular degeneration. Nutrition Reviews, 73(7), 448-462. [More Information]
  • Broadhead, G., Chang, A. (2015). Intravitreal aflibercept for choroidal neovascularisation complicating chronic central serous chorioretinopathy. Graefes Archive for Clinical and Experimental Ophthalmology, 253(6), 979-981. [More Information]
  • Zhu, M., Chew, J., Broadhead, G., Luo, K., Joachim, N., Hong, T., Syed, A., Chang, A. (2015). Intravitreal Ranibizumab for neovascular Age-related macular degeneration in clinical practice: five-year treatment outcomes. Graefes Archive for Clinical and Experimental Ophthalmology, 253(8), 1217-1225. [More Information]
  • Broadhead, G., Hong, T., Zhu, M., Li, H., Schlub, T., Wijeyakumar, W., Chang, A. (2015). Response of pigment epithelial detachments to intravitreal aflibercept among patients with treatment-resistant neovascular age-related macular degeneration. Retina: the Journal of Retinal and Vitreous Diseases, 35(5), 975-981. [More Information]
  • Chang, A., Li, H., Broadhead, G., Luo, K., Zhu, M. (2015). Safety and Efficacy of Intravitreal Preservative-Free Triamcinolone Acetonide (Triesence) for Macular Edema. Journal of Ocular Pharmacology and Therapeutics, 31(9), 563-569. [More Information]
  • Chang, A., Hong, T., Ewe, Y., Bahrami, B., Broadhead, G. (2015). The role of aflibercept in the management of diabetic macular edema. Drug Design, Development and Therapy, 9, 4389-4396. [More Information]

2014

  • Broadhead, G., Chang, A. (2014). Acetazolamide for cystoid macular oedema in Bietti crystalline retinal dystrophy. Korean Journal of Ophthalmology, 28(2), 189-191. [More Information]
  • Chang, A., Li, H., Broadhead, G., Hong, T., Schlub, T., Wijeyakumar, W., Zhu, M. (2014). Intravitreal Aflibercept for Treatment-Resistant Neovascular Age-related Macular Degeneration. Ophthalmology, 121(1), 188-192. [More Information]
  • Broadhead, G., Hong, T., Chang, A. (2014). Treating the untreatable patient: Current options for the management of treatment-resistant neovascular age-related macular degeneration. Acta Ophthalmologica, 92(8), 713-723. [More Information]

2013

  • Broadhead, G., Chang, A. (2013). Choroidal neovascularization in acquired partial lipodystrophy. European Journal of Ophthalmology, 23(3), 439-441. [More Information]
  • Wang, Y., Chang, A. (2013). Clinical features and PDT effect of patients with CCSC. Guoji Yanke Zazhi (International Eye Science), 13(3), 522-526. [More Information]
  • Chui, J., Herkes, G., Chang, A. (2013). Management of fingolimod-associated macular edema. JAMA Ophthalmology, 131(5), 694-696. [More Information]

2012

  • Simunovic, M., Rush, R., Hunyor, A., Chang, A. (2012). Endophthalmitis following intravitreal injection versus endophthalmitis following cataract surgery: clinical features, causative organisms and post-treatment outcomes. British Journal of Ophthalmology, 96(6), 862-866. [More Information]

2007

  • Merani, R., Hunyor, A., Playfair, T., Chang, A., Gregory-Roberts, J., Hunyor, A., Azar, D., Cumming, R. (2007). Pars Plana Vitrectomy for the Management of Retained Lens Material After Cataract Surgery. American Journal of Ophthalmology, 144(3), 364-370. [More Information]

2006

  • Chong, C., Chang, A. (2006). Traumatic optic nerve avulsion and central retinal artery occlusion following rugby injury. Clinical and Experimental Ophthalmology, 34(1), 88-89.

2005

  • Jiang, W., Zhong, Z., Henson, J., Neumann, A., Chang, A., Reddel, R. (2005). Suppression of Alternative Lengthening of Telomeres by Sp100-Mediated Sequestration of the MRE11/RAD50/NBS1 Complex. Molecular and Cellular Biology, 25(7), 2708-2721. [More Information]
  • Chang, A., Zhu, M., Billson, F. (2005). The Interaction of Indocyanine Green with Human Retinal Pigment Epithelium. Investigative Ophthalmology and Visual Science, 46(4), 1463-1467. [More Information]
  • Chang, A., Cha, J., Koentgen, F., Reddel, R. (2005). The murine stanniocalcin 1 gene is not essential for growth and development. Molecular and Cellular Biology, 25(23), 10604-10610. [More Information]
  • Wong, J., Sachdev, N., Beaumont, P., Chang, A. (2005). Visual outcomes following vitrectomy and peeling of epiretinal membrane. Clinical and Experimental Ophthalmology, 33(4), 373-378. [More Information]
  • Sirimaharaj, M., Balachandran, C., Chan, W., Hunyor, A., Chang, A., Gregory-Roberts, J., Hunyor, A., Playfair, T. (2005). Vitrectomy with short term postoperative tamponade using perfluorocarbon liquid for giant retinal tears. British Journal of Ophthalmology, 89(9), 1176-1179. [More Information]

2004

  • Chang, A., Raik, E., Marsden, K., Ma, D. (2004). Australasian CD34+ Quality Assurance Program And Rationale For The Clinical Utility Of The Single-Platform Method For CD34+ Cell Enumeration. Cytotherapy, 6(1), 50-61.
  • Chang, A., Zhu, M., Billson, F., Kumar, N., Beaumont, P. (2004). Indocyanine green localisation in surgically excised choroidal neovascular membrane in age-related macular degeneration. British Journal of Ophthalmology, 88(2), 307-309.

2003

  • Chang, A., Guyer, D., Orlock, D., Yannuzzi, L. (2003). Age-dependent variations in the drusen fluorescence on indocyanine green angiography. Clinical and Experimental Ophthalmology, 31(4), 300-304. [More Information]
  • Chang, A., Jellinek, D., Reddel, R. (2003). Mammalian stanniocalcins and cancer. Endocrine-Related Cancer, 10(3), 359-373.

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