Dr Elena Bagley
D06 - Blackburn Building
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Dr Bagley is a senior lecturer in the Discipline of Pharmacology. [More...]
Dr Bagley is a senior lecturer in the Discipline of Pharmacology.
Dr Bagley completed a PhD at The University of Sydney in 2001. She was a C.J Martin Fellow from 2001 to 2006. During this time she was a postdoctoral fellow in the laboratory of Professor Gary Westbrook at the Vollum Institute (Oregon, USA) and at the Pain Management Research Institute (University of Sydney). [Hide detail]
The laboratory primarily focuses on synapses, which are the point of communication between brain cells. We are interested in normal synaptic function and synapse dysfuntion. Synaptic dysfunction is emerging as a key player in many brain disorders. We use patch-clamp electrophysiology in brain slices, immunohistochemistry and biochemical assays to study synaptic properties and synaptic plasticity that may participate in physiological or pathophysiological processes. Of particular interest are the synaptic changes or plasticity that may be responsible for chronic pain states, neurodevelopmental problems and drug addiction. We also use behavioural assays to try to understand the role of these synaptic changes in the whole animal.
Current national competitive grants*
Endogenous opioids in the amygdala
Bagley E, McNally G
National Health and Medical Research Council / Project Grants ($365,222 over 3 years)
* Grants administered through the University of Sydney
United States. (Oregon Health & Sciences University) Dr Sue Aicher and I collaborate on location and role endogenous opioids in the Amygdala.