Professor Ben Freedman

OAM
Professor of Cardiology
Medicine, Concord Clinical School
ANZAC Research Institute

Telephone +61 2 9767 7358
Fax +61 2 9767 6780

Map

Research interests

inflammation and thrombosis in coronary artery disease, secondary prevention after heart attack

International links

Hong Kong S.A.R.

(Chinese University of Hong Kong) Research collaborations on inflammation links between rheumatoid arthritis and vascular disease. Links with Associate Professors LS Tam, and Gabriel Yip

Selected grants

2013

  • Using innovative technology to identify postoperative atrial fibrillation in cardiac surgical patients after hospital discharge; Lowres N, Neubeck A, Kirkness A, Gallagher R, Freedman B; Sydney Medical School/Cardiothoracic Research Grant.
  • IVIS Lumina II in vivo Imaging System; Seibel M, Handelsman D, Le Couteur D, Hart D, Nicholson G, Freedman B, Kritharides L, Jessup W, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, McMahon A, Simanainen U, Kockx M, Speranza T, Zheng Y; DVC Research/Equipment Grant.

2012

  • Approaches to inhibit SAA-induced endothelial dysfunction and atherosclerosis; Witting P, Freedman B, Geczy C, Skilton M, Sullivan D; Heart Foundation of Australia/Grants-in-Aid.

2010

  • The Lunar PIXImus II DEXA Scanner; Zhou H, Seibel M, Handelsman D, Le Couteur D, Nicholson G, Clarke S, Robertson G, van Zandwijk N, Freedman B, Kennerson M, Allan C, Walters K, Cogger V, Blair I, Reid G, Simanainen U; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2009

  • CHOICE study for secondary prevention of heart disease; Freedman B, Redfern J; HCF Health and Medical Research Foundation/Project Grant.

2007

  • Inflammation-associated S100 proteins: links between arthritis and atherosclerosis; Geczy A, McNeill P, Freedman B, Hsu M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Patient-centred modular secondary prevention following acute coronary syndrome (ACS): a randomised multicentre trial; Freedman B; The Phillip Bushell Foundation/Research Grant.

2006

  • KODAK Image Station 2000mm Multi-Modal Imager; Seibel M, Nicholson G, Witting P, Le Couteur D, Freedman B, Dunstan C, Blair J, Kennerson M, Myers S, Muller M; University of Sydney/Major Equipment.
  • Cell culture quarantine and storage facility plus assessories; Dunstan C, Witting P, Myers S, Handelsman D, Seibel M, Nicholson G, Zhou H, Kennerson M, Allan C, Freedman B, Le Couteur D, Muller M; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Serum Amyloid A As A Mediator Of Thrombotic Risk In Coronary Atherosclerosis; Freedman B, Geczy C, Song C, Geczy C; National Heart Foundation/Grants-in-Aid.

2005

  • Bio-Rad iCycler iQ5 Real-Time PCR & Mutation detection system; Seibel M, Le Couteur D, Freedman B, Nicholson G, Handelsman D, Kennerson M, Dunstan C, Allan C, Witting P, Kril J, Muller M; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Outcomes of local facilitation program of finding and motivating principal investigators in studies for treatment of stable coronory artery disease; Guez D, Freedman B; Servier Laboratories Australia/Research Support.

2004

  • Effects of patient-centered modular secondary prevention in people with acute coronary syndrome.; Ellis E, Freedman B, Redfern J, Briffa T; National Heart Foundation/Research Grant.

2000

  • Reperfusion injury after thrombolytic therapy for myocardial infarction; Freedman B, Meikle S, Jeremy R, Bautovich G; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Wang, X., Cai, X., Freedman, B., Witting, P. (2013). Role of SAA in Promoting Endothelial Activation: Inhibition by High-Density Lipoprotein. In Sabina Janciauskiene (Eds.), Acute Phase Proteins, (pp. 77-101). Rijeka, Croatia: InTech Publishers.
  • Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
  • Kritharides, L., Brieger, D., Freedman, B., Lowe, H. (2005). Treatment of vulnerable plaques: current and future strategies. In Levon Michael Khachigian (Eds.), High-risk atherosclerotic plaques: mechanisms, imaging, models, and therapy, (pp. 161-202). USA: CRC Press.
  • Allman, K., Freedman, B., Beller, G. (2004). Prognosis In Patients With Known Or Suspected Coronary Artery Disease. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 1131-1148). Edinburgh: Churchill Livingstone.
  • Freedman, B., Isner, J. (2003). Therapeutic angiogenesis for coronary artery disease. In Vossoughi, Kipshidze, Moses, Karanian (Eds.), Angiogenesis: Bench to Bedside, (pp. 3-40). Korea: Medical and Engineering Publishers, Inc.
  • Freedman, B., Isner,, J. (2001). Therapeutic angiogenesis for coronary artery disease. In LH Opie, DM Yellon (Eds.), Cardiology at the Limits IV, (pp. 129-158). Cape Town, South Africa: Sage Publications.

Journals

  • Martinez, C., Katholing, A., Freedman, B. (2014). Adverse prognosis of incidentally detected ambulatory atrial fibrillation. Thrombosis and Haemostasis, 112(2), 276-286. [More Information]
  • Lowres, N., Neubeck, A., Salkeld, G., Krass, I., McLachlan, A., Redfern, J., Bennett, A., Briffa, T., Bauman, A., Martinez, C., Lau, J., Brieger, D., Sy, R., Freedman, B., et al (2014). Feasibility and cost effectiveness of stroke prevention through community screening for atrial fibrillation using iPhone ECG in pharmacies: The SEARCH-AF study. Thrombosis and Haemostasis, 111(6), 1167-1176. [More Information]
  • Orchard, J., Freedman, B., Lowres, N., Peiris, D., Neubeck, A. (2014). iPhone ECG screening by practice nurses and receptionists for atrial fibrillation in general practice: the GP-SEARCH qualitative pilot study. Australian Family Physician, 43(5), 315-319.
  • Hong Duong, T., Chami, B., McMahon, A., Fong, G., Dennis, J., Freedman, B., Witting, P. (2014). Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury. Journal of Neurochemistry, 130(6), 733-747. [More Information]
  • Ng, A., Yong, A., Chow, V., Chung, T., Freedman, B., Kritharides, L. (2013). Cardiac troponin-T and the prediction of acute and long-term mortality after acute pulmonary embolism. International Journal of Cardiology, 165(1), 126-133. [More Information]
  • Neubeck, A., Orchard, J., Freedman, B. (2013). Fog on the crystal ball? Missing atrial fibrillation in forecasting the future of stroke. Stroke, 44(10), e136-e136. [More Information]
  • Lau, J., Lowres, N., Neubeck, A., Brieger, D., Sy, R., Galloway, C., Albert, D., Freedman, B. (2013). iPhone ECG application for community screening to detect silent atrial fibrillation: A novel technology to prevent stroke. International Journal of Cardiology, 165(1), 193-194. [More Information]
  • Clark, T., Freedman, B., Croft, A., Dalton, H., Luscombe, G., Brown, A., Tiller, D., Frommer, M. (2013). Medical graduates becoming rural doctors: rural background versus extended rural placement. Medical Journal of Australia, 199(11), 779-782. [More Information]
  • Deif, B., Lowres, N., Freedman, B. (2013). Screening for atrial fibrillation above age 65 detects an asymptomatic subset at high risk of stroke. International Journal of Cardiology, 164(3), 371-372. [More Information]
  • Lowres, N., Neubeck, A., Redfern, J., Freedman, B. (2013). Screening to identify unknown atrial fibrillation: A systematic review. Thrombosis and Haemostasis, 110(2), 213-222. [More Information]
  • Cai, X., Freedman, B., Witting, P. (2013). Serum amyloid A stimulates cultured endothelial cells to migrate and proliferate: Inhibition by the multi-kinase inhibitor BIBF112. Clinical and Experimental Pharmacology and Physiology, 40(9), 662-670. [More Information]
  • Briffa, T., Neubeck, A., Clark, A., Freedman, B., Redfern, J. (2012). Changing the lexicon of 'Cardiac Rehabilitation': a progressive step. European Journal of Preventive Cardiology, 19(2), 167-168. [More Information]
  • Lowres, N., Neubeck, A., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2012). Lifestyle risk reduction interventions in atrial fibrillation: a systematic review. European Journal of Preventive Cardiology, 19(5), 1091-1100. [More Information]
  • Neubeck, A., Freedman, B., Clark, A., Briffa, T., Bauman, A., Redfern, J. (2012). Participating in cardiac rehabilitation: a systematic review and meta-synthesis of qualitative data. European Journal of Cardiovascular Prevention and Rehabilitation, 19(3), 494-503. [More Information]
  • Lowres, N., Freedman, B., Redfern, J., McLachlan, A., Krass, I., Bennett, A., Briffa, T., Bauman, A., Neubeck, A. (2012). Screening Education And Recognition in Community pHarmacies of Atrial Fibrillation to prevent stroke in an ambulant population aged >65 years (SEARCH-AF stroke prevention study): a cross-sectional study protocol. BMJ Open, 2(3), 1-6. [More Information]
  • Sy, R., Freedman, B. (2011). Beta-Blocker Dose Up-Titration or Addition of Ivabradine in Stable Angina: More is Not Necessarily Better. Cardiovascular Drugs and Therapy, 25(6), 501-502. [More Information]
  • Ceconi, C., Freedman, B., Tardif, J., Hildebrandt, P., McDonagh, T., Gueret, P., Parrinello, G., Robertson, M., Steg, P., Tendera, M., et al (2011). Effect of heart rate reduction by ivabradine on left ventricular remodeling in the echocardiographic substudy of BEAUTIFUL. International Journal of Cardiology, 146(3), 408-414. [More Information]
  • Tam, L., Li, E., Shang, Q., Tomlinson, B., Lee, V., Lee, K., Li, M., Kuan, W., Li, T., Tseung, L., Freedman, B., et al (2011). Effects of rosuvastatin on subclinical atherosclerosis and arterial stiffness in rheumatoid arthritis: A randomized controlled pilot trial. Scandinavian Journal of Rheumatology, 40(6), 411-421. [More Information]
  • Neubeck, A., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2011). Four-year follow-up of the Choice of Health Options In prevention of Cardiovascular Events randomized controlled trial. European Journal of Cardiovascular Prevention and Rehabilitation, 18(2), 278-286. [More Information]
  • Neubeck, A., Redfern, J., Freedman, B. (2011). Letter by neubeck et Al regarding article, impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community. Circulation, 124(22), e572-e573. [More Information]
  • Neubeck, A., Briffa, T., Freedman, B., Clark, A., Redfern, J. (2011). Nurse-led telephone interventions for people with cardiac disease: The importance of the multi-disciplinary approach. European Journal of Cardiovascular Nursing, 10(1), 70-71. [More Information]
  • Neubeck, A., Ascanio, R., Bauman, A., Briffa, T., Clark, A., Freedman, B., Redfern, J. (2011). Planning locally relevant Internet programs for secondary prevention of cardiovascular disease. European Journal of Cardiovascular Nursing, 10(4), 213-220. [More Information]
  • Witting, P., Song, C., Hsu, K., Hua, S., Parry, S., Aran, R., Geczy, C., Freedman, B. (2011). The acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoprotein. Free Radical Biology and Medicine, 51(7), 1390-1398. [More Information]
  • Redfern, J., Menzies, M., Briffa, T., Freedman, B. (2010). Impact of medical consultation frequency on modifiable risk factors and medications at 12 months after acute coronary syndrome in the CHOICE randomised controlled trial. International Journal of Cardiology, 145(3), 481-486. [More Information]
  • Ng, A., Davis, G., Chow, C., Coats, A., Sindone, A., Freedman, B. (2010). Impact of sleep disordered breathing severity on hemodynamics, autonomic balance and cardiopulmonary functional status in chronic heart failure. International Journal of Cardiology, 141(3), 227-235. [More Information]
  • Alcock, R., Roy, P., Adorini, K., Lau, G., Kritharides, L., Lowe, H., Brieger, D., Freedman, B. (2010). Incidence and determinants of myocardial infarction following percutaneous coronary interventions according to the revised Joint Task Force definition of troponin T elevation. International Journal of Cardiology, 140, 66-72. [More Information]
  • Ayer, J., Song, C., Steinbeck, K., Celermajer, D., Freedman, B. (2010). Increased Tissue Factor Activity in Monocytes from Obese Young Adults. Clinical and Experimental Pharmacology and Physiology, 37(11), 1049-1054. [More Information]
  • Tiong, A., Lowe, H., Freedman, B., Brieger, D. (2010). Lack of widespread inflammation after contemporary PCI. International Journal of Cardiology, 140(1), 82-87. [More Information]
  • Medi, C., Hankey, G., Freedman, B. (2010). Stroke Risk and Antithrombotic Strategies in Atrial Fibrillation. Stroke, 41(11), 2705-13. [More Information]
  • Chung, T., Yiannikas, J., Freedman, B., Kritharides, L. (2010). Unusual features of apical hypertrophic cardiomyopathy. The American Journal of Cardiology, 105(6), 879-883. [More Information]
  • Hua, S., Song, C., Geczy, C., Freedman, B., Witting, P. (2009). A role for acute-phase serum amyloid A and high-density lipoprotein in oxidative stress, endothelial dysfunction and atherosclerosis. Redox Report, 14(5), 187-196. [More Information]
  • Brieger, D., Kelly, A., Aroney, C., Tideman, P., Freedman, B., Chew, D., Ilton, M., Carroll, G., Jacobs And, I., Huang, N., et al (2009). Acute coronary syndromes: consensus recommendations for translating knowledge into action. Medical Journal of Australia, 191(6), 334-338. [More Information]
  • Brieger, D., Freedman, B. (2009). Delirium cordis: can we predict the onset of atrial fibrillation? The Lancet, 373(9665), 698-700. [More Information]
  • Goyette, J., Yan, W., Yamen, E., Chung, Y., Lim, S., Hsu, K., Rahimi, F., Di Girolamo, N., Song, C., Jessup, W., Freedman, B., et al (2009). Pleiotropic roles of S100A12 in coronary atherosclerotic plaque formation and rupture. Journal of Immunology, 183(1), 593-603. [More Information]
  • Song, C., Hsu, K., Yamen, E., Yan, W., Fock, J., Witting, P., Geczy, C., Freedman, B. (2009). Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytes. Atherosclerosis, 207(2), 374-383. [More Information]
  • Song, C., Shen, Y., Yamen, E., Hsu, K., Yan, W., Witting, P., Freedman, B., Geczy, C. (2009). Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes. Atherosclerosis, 202(2), 596-604. [More Information]
  • Medi, C., Kalman, J., Freedman, B. (2009). Supraventricular tachycardia. Medical Journal of Australia, 190(5), 255-260. [More Information]
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). Telehealth interventions for the secondary prevention of coronary heart disease: a systematic review. European Journal of Cardiovascular Prevention and Rehabilitation, 16(3), 281-289. [More Information]
  • Rubboli, A., Halperin, J., Airaksinen, K., Buerke, M., Eeckhout, E., Freedman, B., Gershlick, A., Schlitt, A., Tse, H., Verheugt, F., et al (2008). Antithrombotic therapy in patients treated with oral anticoagulation undergoing coronary artery stenting. An expert consensus document with focus on atrial fibrillation. Annals of Medicine, 40(6), 428-36. [More Information]
  • Redfern, J., Briffa, T., Ellis, E., Freedman, B. (2008). Choice of secondary prevention improves risk factors after acute coronary syndrome: one year follow-up of the CHOICE (Choice of Health Options In prevention of Cardiovascular Events) randomised controlled trial. Heart, Published Online: doi:10.1136/hrt.2008.150870, 1-17. [More Information]
  • Ng, A., Sindone, A., Wong, H., Freedman, B. (2008). Differences in management and outcome of ischemic and non-ischemic cardiomyopathy. International Journal of Cardiology, 129, 198-204. [More Information]
  • Fox, K., Ford, I., Steg, P., Tendera, M., Ferrari, R., Freedman, B., Tofler, G. (2008). Ivabridine for patients with stable coronary artery disease and left-ventricular systolic function (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. The Lancet, 372(9641), 807-816. [More Information]
  • Chung, T., Sindone, A., Freedman, B. (2008). Letter by Chung et al regarding article, N-terminal pro B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure: primary results of the Canadian Prospective Randomized Multicenter IMPROVE-CHF study".". Circulation (Baltimore), 117(1), e5; author reply e6. [More Information]
  • Dwyer, J., Redfern, J., Freedman, B. (2008). Low utilisation of cardiovascular risk reducing therapy in patients with acute coronary syndromes and non-obstructive coronary artery disease. International Journal of Cardiology, 129, 394-398. [More Information]
  • Page Mitchell, S., Birden, H., Hudson, J., Thistlethwaite, J., Roberts, C., Wilson, I., Bushnell, J., Hogg, J., Freedman, B., Yeomans, N. (2008). Medical schools can cooperate: A new joint venture to provide medical education in the Northern Rivers Region of New South Wales. Medical Journal of Australia, 188(3), 179-181. [More Information]
  • Redfern, J., Briffa, T., Ellis, E., Freedman, B. (2008). Patient-centered modular secondary prevention following acute coronary syndrome: a randomized controlled trial. Journal of Cardiopulmonary Rehabilitation and Prevention, 28, 107-115. [More Information]
  • Witting, P., Zeng, B., Wong, M., McMahon, A., Rayner, B., Sapir, A., Lowe, H., Freedman, B., Brieger, D. (2008). Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice. Thrombosis Research, 122(5), 674-682. [More Information]
  • Emmett, L., Van Gaal, W., Magee, M., Bass, S., Ali, O., Freedman, B., Van Der Wall, H., Kritharides, L. (2008). Prospective evaluation of the impact of diabetes and left ventricular hypertrophy on the relationship between ischemia and transient ischemic dilation of the left ventricle on single-day adenosine Tc-99m myocardial perfusion imaging. Journal of Nuclear Cardiology, 15(5), 638-643. [More Information]
  • Ng, A., Freedman, B. (2008). Sleep disordered breathing in chronic heart failure. Heart Failure Reviews, DOI 10.1007/s10741-008-9096-8, 1-11. [More Information]
  • Neubeck, A., Redfern, J., Briffa, T., Bauman, A., Hare, D., Freedman, B. (2008). The CHOICE (Choice of Health Options In prevention of Cardiovascular Events) replication trial: study protocol. BMC Cardiovascular Disorders, 8(25), 25-1-25-7. [More Information]
  • Lowe, H., Freedman, B. (2008). The late open artery hypothesis: the case and the artery remain closed. European heart journal, 30, 129-30. [More Information]
  • Medi, C., Hankey, G., Freedman, B. (2007). Atrial fibrillation. Medical Journal of Australia, 186(4), 197-202. [More Information]
  • Ng, A., Freedman, B., Sindone, A. (2007). Autonomic abnormalities in congestive heart failure patients with sleep-disordered breathing. Journal of Cardiac Failure, 13(5), 395-400. [More Information]
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2007). High risk-factor level and low risk-factor knowledge in patients not accessing cardiac rehabilitation after acute coronary syndrome. Medical Journal of Australia, 186(1), 21-25. [More Information]
  • Cai, H., Song, C., Endoh, I., Goyette, J., Jessup, W., Freedman, B., McNeil, H., Geczy, C. (2007). Serum amyloid A induces monocyte tissue factor. Journal of Immunology, 178(3), 1852-1860. [More Information]
  • Song, C., Nakagomi, A., Chandar, S., Cai, H., Lim, I., McNeil, H., Freedman, B., Geczy, C. (2006). C-reactive protein contributes to the hypercoagulable state in coronary artery disease. Journal of Thrombosis and Haemostasis, 4(1), 98-106. [More Information]
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2006). Development and testing of innovative patient resources for the management of coronary heart disease (CHD): a descriptive study. BMC Health Services Research, 6, 95-1-95-9. [More Information]
  • Lau, G., Ridley, L., Bannon, P., Freedman, B., Brieger, D., Sullivan, D., Wong, L., Kritharides, L. (2006). Hypertriglyceridaemia is associated with early non-patency of coronary bypass grafts. Heart, 92(4), 536-538. [More Information]
  • Chung, T., Sindone, A., Foo, F., Dwyer, A., Paoloni, R., Janu, M., Wong, H., Hall, J., Freedman, B. (2006). Influence of history of heart failure on diagnostic performance and utility of B-type natriuretic peptide testing for acute dyspnea in the emergency department. American Heart Journal, 152(5), 949-955. [More Information]
  • Lau, G., Ridley, L., Bannon, P., Wong, L., Trieu, J., Brieger, D., Lowe, H., Freedman, B., Kritharides, L. (2006). Lumen loss in the first year in saphenous vein grafts is predominantly a result of negative remodeling of the whole vessel rather than a result of changes in wall thickness. Circulation, 114(1), I435-I440. [More Information]
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2006). Modular prevention of heart disease following acute coronary syndrome (ACS) [ISRCTN42984084]. BMC Cardiovascular Disorders, 6(26), 1. [More Information]
  • Prasan, A., Bhagwandeen, R., Solanki, V., Freedman, B., Brieger, D. (2006). Serial Angiography in Patients with Acute Coronary Syndromes: Effect of Antithrombotic Therapy on Angiographic Lesion Severity. Heart, Lung and Circulation, 15(6), 378-382. [More Information]
  • Lowe, H., Freedman, B. (2006). What do we know about perioperative ischaemic cardiac events in patients undergoing non-cardiac surgery? Medical Journal of Australia, 184(8), 376-377.
  • Lau, G., Ridley, L., Schieb, M., Brieger, D., Freedman, B., Wong, L., Lo, S., Kritharides, L. (2005). Coronary artery stenoses: detection with calcium scoring, CT angiography, and both methods combined. Radiology, 235(2), 415-422. [More Information]
  • Briffa, T., Eckermann, S., Griffiths, A., Harris, P., Heath, M., Freedman, B., Donaldson, L., Briffa, N., Keech, A. (2005). Cost-effectiveness of rehabilitation after an acute coronary event: a randomised controlled trial. Medical Journal of Australia, 183(9), 450-455. [More Information]
  • Zeng, B., Prasan, A., Fung, K., Solanki, V., Bruce, D., Freedman, B., Brieger, D. (2005). Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease. Internal Medicine Journal, 35(6). [More Information]
  • Emmett, L., Magee, M., Freedman, B., Van Der Wall, H., Bush, V., Trieu, J., Van Gaal, W., Allman, K., Kritharides, L. (2005). The role of left ventricular hypertrophy and diabetes in the presence of transient ischemic dilation of the left ventricle on myocardial perfusion SPECT images. The Journal of Nuclear Medicine, 46(10), 1596-1601. [More Information]
  • Allman, K., Freedman, B. (2004). Emergency department assessment of patients with acute chest pain: myocardial perfusion imaging, blood tests, or both? Journal of Nuclear Cardiology, 11(1), 87-89.
  • Tiong, A., Freedman, B. (2004). Gene Therapy For Cardiovascular Disease: The Potential Of VEGF. Current Opinion in Molecular Therapeutics, 6(2), 151-159.
  • Lau, G., Brieger, D., Freedman, B. (2004). Infarction due to right coronary artery thrombus. Clinical Cardiology (Hoboken): an indexed and peer-reviewed journal for advances in the treatment of cardiovascular disease, 27(2), 96-96.
  • Beltrame, J., Turner, S., Leslie, S., Solomon, P., Freedman, B., Horowitz, J. (2004). The Angiographic And Clinical Benefits Of Mibefradil In The Coronary Slow Flow Phenomenon. Journal of the American College of Cardiology, 44(1), 57-62. [More Information]
  • Pepine, C., Rouleau, J., Annis, K., Ducharme, A., Ma, P., Lenis, J., Davies, R., Thadani, U., Chaitman, B., Haber, H., Freedman, B., et al (2003). Effects of Angiotensin-converting enzyme inhibition on transient ischemia: The Quinapril anti-ischemia and symptoms of angina reduction (QUASAR) Trial. Journal of the American College of Cardiology, 42(12), 2049-2059. [More Information]
  • Freedman, B. (2002). Clinical trials of gene therapy for atherosclerotic cardiovascular disease. Current Opinion in Lipidology, 13(6), 653-661.
  • Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, , 473-475.
  • Zeng, B., Bruce, D., Kril, J., Ploplis, V., Freedman, B., Brieger, D. (2002). Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis. Thrombosis and Haemostasis, 88, 805-810.
  • Brieger, D., Solanki, V., Gaynor, M., Booth, V., MacDonald, R., Freedman, B. (2002). Optimal strategy for administering Enoxaparin to patients undergoing coronary angiography without angioplasty for acute coronary syndromes. The American Journal of Cardiology, 89(10), 1167-1170.
  • Freedman, B., Vale, P., Kalka, C., Kearney, M., Pieczek, A., Symes, J., Losordo, D., Isner, J. (2002). Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA. Human Gene Therapy, 13(13), 1595-1603.
  • Freedman, B., Isner, J. (2002). Therapeutic angiogenesis for coronary artery disease. Annals of Internal Medicine, , 54-71.
  • Freedman, B., Isner,, J. (2001). Therapeutic angiogenesis for ischemic cardiovascular disease. Journal of Molecular and Cellular Cardiology, 33, 379-393.

Conferences

  • Neubeck, A., Lowres, N., Redfern, J., Freedman, B. (2013). Choice of Health Options In Prevention of Cardiovascular Events - Atrial Fibrillation (CHOICE AF) pilot study. 7th Annual Conference of the Australasian Cardiovascular Nursing College (ACNC) 2013, Auckland, New Zealand.
  • Neubeck, A., Lowres, N., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2013). One year outcomes of the Choice of Health Options in prevention of Cardiovascular Events (CHOICE) replication trial. EuroPRevent 2013 The European Association for Cardiovascular Prevention and Rehabilitation Annual Meeting (EACPR), Rome, Italy.
  • Lowres, N., Neubeck, A., Redfern, J., McLachlan, A., Krass, I., Bennett, A., Briffa, T., Salkeld, G., Brieger, D., Sy, R., Bauman, A., Freedman, B. (2013). Screening Education and Recognition in Community Pharmacies of Atrial Fibrillation to Prevent stroke (SEARCH-AF Stroke Prevention Study). 61st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2013, Gold Coast, Queensland, Australia. [More Information]
  • Neubeck, A., Lowres, N., Freedman, B., Briffa, T., Bauman, A., Rogers, K., Redfern, J. (2013). Two year outcomes of the Choice of Health Options in preventions of Cardiovascular Events (CHOICE) replication study. 61st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2013, Gold Coast, Queensland, Australia. [More Information]
  • Lowres, N., Neubeck, A., Redfern, J., Freedman, B. (2012). Community Screening Programs to Identify Unknown Atrial Fibrillation: A Systematic Review. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Lowres, N., Redfern, J., Freedman, B., Van Der Ploeg, H., Bauman, A., Neubeck, A. (2012). Validity of a modified Active Australia Survey in a cardiovascular secondary prevention population. 22nd Australian Cardiovascular Health and Rehabilitation Association (ACRA) Annual Conference 2012, Brisbane, Queensland, Australia.
  • Neubeck, A., Freedman, B., Clark, A., Briffa, T., Bauman, A., Redfern, J. (2011). Barriers to participating in cardiac rehabilitation: A systematic review and meta-synthesis of qualitative data. Cardiovascular Health and Rehabilitation Association State Conference 2011 NSW/ACT, Sydney, NSW, Australia.
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). A systematic review of telehealth interventions for coronary heart disease. 19th Australian Cardiovascular Health and Rehabilitation Association (ACRA) Annual Conference 2009, Sydney, NSW, Australia.
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). A systematic review of telehealth interventions for coronary heart disease. 2009 National Heart Foundation Conference, Brisbane, Queensland, Australia.
  • Neubeck, A., Redfern, J., Briffa, T., Ascanio, R., Freedman, B. (2009). Cardiovascular risk benefits of the CHOICE (Choice of Health Options in reducing Cardiovascular Events) program are maintained for 4 years: Randomised controlled trial. 57th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2009, Australia: Cardiac Society of Australia and New Zealand.
  • Neubeck, A., Menzies, M., Redfern, J., Briffa, T., Freedman, B. (2008). Impact of medical consultation frequency on charge in risk factors after acute coronary syndrome. 16th Annual Cardiovascular Health and Rehabilitation Association State Conference 2008 NSW/ACT, Canberra, Australian Capital Territory, Australia.
  • Ng, A., Chow, C., Wong, H., Sindone, A., Davis, G., Freedman, B. (2008). Impact of sleep disordered breathing severity on the hemodynamics, functional status and autonomic function of chronic heart failure patients. 4th Asian Pacific Congress of Heart Failure 2008, Australia: Elsevier.
  • Ng, A., Chow, C., Wong, H., Sindone, A., Davis, G., Freedman, B. (2007). Anthropometric Characteristics of Patients With Chronic Heart Failure and Severe Sleep Disordered Breathing. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.
  • Ng, A., Davis, G., Chow, C., Wong, H., Sindone, A., Freedman, B. (2007). Chronic Heart Failure Patients With Sleep Disordered Breathing: Functional Assessment and Response to Exercise. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.
  • Ng, A., Davis, G., Chow, C., Wong, H., Sindone, A., Freedman, B. (2007). Severity of Sleep Disordered Breathing (SDB) is Associated with Altered Heart Rate Variability (HRV) in Chronic Heart Failure. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.

Magazine / Newspaper Articles

  • Freedman, B. (2001). Cytomegalovirus seropositivity and C-reactive protein have indepent and combined prognostic predictive value for mortality in patients with angiographically demonstrated coronary artery disease. Circulation.
  • Freedman, B. (2001). Tremor-induced ECG artifact mimicking ventricular tachycardia. Circulation.

2014

  • Martinez, C., Katholing, A., Freedman, B. (2014). Adverse prognosis of incidentally detected ambulatory atrial fibrillation. Thrombosis and Haemostasis, 112(2), 276-286. [More Information]
  • Lowres, N., Neubeck, A., Salkeld, G., Krass, I., McLachlan, A., Redfern, J., Bennett, A., Briffa, T., Bauman, A., Martinez, C., Lau, J., Brieger, D., Sy, R., Freedman, B., et al (2014). Feasibility and cost effectiveness of stroke prevention through community screening for atrial fibrillation using iPhone ECG in pharmacies: The SEARCH-AF study. Thrombosis and Haemostasis, 111(6), 1167-1176. [More Information]
  • Orchard, J., Freedman, B., Lowres, N., Peiris, D., Neubeck, A. (2014). iPhone ECG screening by practice nurses and receptionists for atrial fibrillation in general practice: the GP-SEARCH qualitative pilot study. Australian Family Physician, 43(5), 315-319.
  • Hong Duong, T., Chami, B., McMahon, A., Fong, G., Dennis, J., Freedman, B., Witting, P. (2014). Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury. Journal of Neurochemistry, 130(6), 733-747. [More Information]

2013

  • Ng, A., Yong, A., Chow, V., Chung, T., Freedman, B., Kritharides, L. (2013). Cardiac troponin-T and the prediction of acute and long-term mortality after acute pulmonary embolism. International Journal of Cardiology, 165(1), 126-133. [More Information]
  • Neubeck, A., Lowres, N., Redfern, J., Freedman, B. (2013). Choice of Health Options In Prevention of Cardiovascular Events - Atrial Fibrillation (CHOICE AF) pilot study. 7th Annual Conference of the Australasian Cardiovascular Nursing College (ACNC) 2013, Auckland, New Zealand.
  • Neubeck, A., Orchard, J., Freedman, B. (2013). Fog on the crystal ball? Missing atrial fibrillation in forecasting the future of stroke. Stroke, 44(10), e136-e136. [More Information]
  • Lau, J., Lowres, N., Neubeck, A., Brieger, D., Sy, R., Galloway, C., Albert, D., Freedman, B. (2013). iPhone ECG application for community screening to detect silent atrial fibrillation: A novel technology to prevent stroke. International Journal of Cardiology, 165(1), 193-194. [More Information]
  • Clark, T., Freedman, B., Croft, A., Dalton, H., Luscombe, G., Brown, A., Tiller, D., Frommer, M. (2013). Medical graduates becoming rural doctors: rural background versus extended rural placement. Medical Journal of Australia, 199(11), 779-782. [More Information]
  • Neubeck, A., Lowres, N., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2013). One year outcomes of the Choice of Health Options in prevention of Cardiovascular Events (CHOICE) replication trial. EuroPRevent 2013 The European Association for Cardiovascular Prevention and Rehabilitation Annual Meeting (EACPR), Rome, Italy.
  • Wang, X., Cai, X., Freedman, B., Witting, P. (2013). Role of SAA in Promoting Endothelial Activation: Inhibition by High-Density Lipoprotein. In Sabina Janciauskiene (Eds.), Acute Phase Proteins, (pp. 77-101). Rijeka, Croatia: InTech Publishers.
  • Lowres, N., Neubeck, A., Redfern, J., McLachlan, A., Krass, I., Bennett, A., Briffa, T., Salkeld, G., Brieger, D., Sy, R., Bauman, A., Freedman, B. (2013). Screening Education and Recognition in Community Pharmacies of Atrial Fibrillation to Prevent stroke (SEARCH-AF Stroke Prevention Study). 61st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2013, Gold Coast, Queensland, Australia. [More Information]
  • Deif, B., Lowres, N., Freedman, B. (2013). Screening for atrial fibrillation above age 65 detects an asymptomatic subset at high risk of stroke. International Journal of Cardiology, 164(3), 371-372. [More Information]
  • Lowres, N., Neubeck, A., Redfern, J., Freedman, B. (2013). Screening to identify unknown atrial fibrillation: A systematic review. Thrombosis and Haemostasis, 110(2), 213-222. [More Information]
  • Cai, X., Freedman, B., Witting, P. (2013). Serum amyloid A stimulates cultured endothelial cells to migrate and proliferate: Inhibition by the multi-kinase inhibitor BIBF112. Clinical and Experimental Pharmacology and Physiology, 40(9), 662-670. [More Information]
  • Neubeck, A., Lowres, N., Freedman, B., Briffa, T., Bauman, A., Rogers, K., Redfern, J. (2013). Two year outcomes of the Choice of Health Options in preventions of Cardiovascular Events (CHOICE) replication study. 61st Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2013, Gold Coast, Queensland, Australia. [More Information]

2012

  • Briffa, T., Neubeck, A., Clark, A., Freedman, B., Redfern, J. (2012). Changing the lexicon of 'Cardiac Rehabilitation': a progressive step. European Journal of Preventive Cardiology, 19(2), 167-168. [More Information]
  • Lowres, N., Neubeck, A., Redfern, J., Freedman, B. (2012). Community Screening Programs to Identify Unknown Atrial Fibrillation: A Systematic Review. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Lowres, N., Neubeck, A., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2012). Lifestyle risk reduction interventions in atrial fibrillation: a systematic review. European Journal of Preventive Cardiology, 19(5), 1091-1100. [More Information]
  • Neubeck, A., Freedman, B., Clark, A., Briffa, T., Bauman, A., Redfern, J. (2012). Participating in cardiac rehabilitation: a systematic review and meta-synthesis of qualitative data. European Journal of Cardiovascular Prevention and Rehabilitation, 19(3), 494-503. [More Information]
  • Lowres, N., Freedman, B., Redfern, J., McLachlan, A., Krass, I., Bennett, A., Briffa, T., Bauman, A., Neubeck, A. (2012). Screening Education And Recognition in Community pHarmacies of Atrial Fibrillation to prevent stroke in an ambulant population aged >65 years (SEARCH-AF stroke prevention study): a cross-sectional study protocol. BMJ Open, 2(3), 1-6. [More Information]
  • Lowres, N., Redfern, J., Freedman, B., Van Der Ploeg, H., Bauman, A., Neubeck, A. (2012). Validity of a modified Active Australia Survey in a cardiovascular secondary prevention population. 22nd Australian Cardiovascular Health and Rehabilitation Association (ACRA) Annual Conference 2012, Brisbane, Queensland, Australia.

2011

  • Neubeck, A., Freedman, B., Clark, A., Briffa, T., Bauman, A., Redfern, J. (2011). Barriers to participating in cardiac rehabilitation: A systematic review and meta-synthesis of qualitative data. Cardiovascular Health and Rehabilitation Association State Conference 2011 NSW/ACT, Sydney, NSW, Australia.
  • Sy, R., Freedman, B. (2011). Beta-Blocker Dose Up-Titration or Addition of Ivabradine in Stable Angina: More is Not Necessarily Better. Cardiovascular Drugs and Therapy, 25(6), 501-502. [More Information]
  • Ceconi, C., Freedman, B., Tardif, J., Hildebrandt, P., McDonagh, T., Gueret, P., Parrinello, G., Robertson, M., Steg, P., Tendera, M., et al (2011). Effect of heart rate reduction by ivabradine on left ventricular remodeling in the echocardiographic substudy of BEAUTIFUL. International Journal of Cardiology, 146(3), 408-414. [More Information]
  • Tam, L., Li, E., Shang, Q., Tomlinson, B., Lee, V., Lee, K., Li, M., Kuan, W., Li, T., Tseung, L., Freedman, B., et al (2011). Effects of rosuvastatin on subclinical atherosclerosis and arterial stiffness in rheumatoid arthritis: A randomized controlled pilot trial. Scandinavian Journal of Rheumatology, 40(6), 411-421. [More Information]
  • Neubeck, A., Freedman, B., Briffa, T., Bauman, A., Redfern, J. (2011). Four-year follow-up of the Choice of Health Options In prevention of Cardiovascular Events randomized controlled trial. European Journal of Cardiovascular Prevention and Rehabilitation, 18(2), 278-286. [More Information]
  • Neubeck, A., Redfern, J., Freedman, B. (2011). Letter by neubeck et Al regarding article, impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community. Circulation, 124(22), e572-e573. [More Information]
  • Neubeck, A., Briffa, T., Freedman, B., Clark, A., Redfern, J. (2011). Nurse-led telephone interventions for people with cardiac disease: The importance of the multi-disciplinary approach. European Journal of Cardiovascular Nursing, 10(1), 70-71. [More Information]
  • Neubeck, A., Ascanio, R., Bauman, A., Briffa, T., Clark, A., Freedman, B., Redfern, J. (2011). Planning locally relevant Internet programs for secondary prevention of cardiovascular disease. European Journal of Cardiovascular Nursing, 10(4), 213-220. [More Information]
  • Witting, P., Song, C., Hsu, K., Hua, S., Parry, S., Aran, R., Geczy, C., Freedman, B. (2011). The acute-phase protein serum amyloid A induces endothelial dysfunction that is inhibited by high-density lipoprotein. Free Radical Biology and Medicine, 51(7), 1390-1398. [More Information]

2010

  • Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
  • Redfern, J., Menzies, M., Briffa, T., Freedman, B. (2010). Impact of medical consultation frequency on modifiable risk factors and medications at 12 months after acute coronary syndrome in the CHOICE randomised controlled trial. International Journal of Cardiology, 145(3), 481-486. [More Information]
  • Ng, A., Davis, G., Chow, C., Coats, A., Sindone, A., Freedman, B. (2010). Impact of sleep disordered breathing severity on hemodynamics, autonomic balance and cardiopulmonary functional status in chronic heart failure. International Journal of Cardiology, 141(3), 227-235. [More Information]
  • Alcock, R., Roy, P., Adorini, K., Lau, G., Kritharides, L., Lowe, H., Brieger, D., Freedman, B. (2010). Incidence and determinants of myocardial infarction following percutaneous coronary interventions according to the revised Joint Task Force definition of troponin T elevation. International Journal of Cardiology, 140, 66-72. [More Information]
  • Ayer, J., Song, C., Steinbeck, K., Celermajer, D., Freedman, B. (2010). Increased Tissue Factor Activity in Monocytes from Obese Young Adults. Clinical and Experimental Pharmacology and Physiology, 37(11), 1049-1054. [More Information]
  • Tiong, A., Lowe, H., Freedman, B., Brieger, D. (2010). Lack of widespread inflammation after contemporary PCI. International Journal of Cardiology, 140(1), 82-87. [More Information]
  • Medi, C., Hankey, G., Freedman, B. (2010). Stroke Risk and Antithrombotic Strategies in Atrial Fibrillation. Stroke, 41(11), 2705-13. [More Information]
  • Chung, T., Yiannikas, J., Freedman, B., Kritharides, L. (2010). Unusual features of apical hypertrophic cardiomyopathy. The American Journal of Cardiology, 105(6), 879-883. [More Information]

2009

  • Hua, S., Song, C., Geczy, C., Freedman, B., Witting, P. (2009). A role for acute-phase serum amyloid A and high-density lipoprotein in oxidative stress, endothelial dysfunction and atherosclerosis. Redox Report, 14(5), 187-196. [More Information]
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). A systematic review of telehealth interventions for coronary heart disease. 19th Australian Cardiovascular Health and Rehabilitation Association (ACRA) Annual Conference 2009, Sydney, NSW, Australia.
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). A systematic review of telehealth interventions for coronary heart disease. 2009 National Heart Foundation Conference, Brisbane, Queensland, Australia.
  • Brieger, D., Kelly, A., Aroney, C., Tideman, P., Freedman, B., Chew, D., Ilton, M., Carroll, G., Jacobs And, I., Huang, N., et al (2009). Acute coronary syndromes: consensus recommendations for translating knowledge into action. Medical Journal of Australia, 191(6), 334-338. [More Information]
  • Neubeck, A., Redfern, J., Briffa, T., Ascanio, R., Freedman, B. (2009). Cardiovascular risk benefits of the CHOICE (Choice of Health Options in reducing Cardiovascular Events) program are maintained for 4 years: Randomised controlled trial. 57th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2009, Australia: Cardiac Society of Australia and New Zealand.
  • Brieger, D., Freedman, B. (2009). Delirium cordis: can we predict the onset of atrial fibrillation? The Lancet, 373(9665), 698-700. [More Information]
  • Goyette, J., Yan, W., Yamen, E., Chung, Y., Lim, S., Hsu, K., Rahimi, F., Di Girolamo, N., Song, C., Jessup, W., Freedman, B., et al (2009). Pleiotropic roles of S100A12 in coronary atherosclerotic plaque formation and rupture. Journal of Immunology, 183(1), 593-603. [More Information]
  • Song, C., Hsu, K., Yamen, E., Yan, W., Fock, J., Witting, P., Geczy, C., Freedman, B. (2009). Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytes. Atherosclerosis, 207(2), 374-383. [More Information]
  • Song, C., Shen, Y., Yamen, E., Hsu, K., Yan, W., Witting, P., Freedman, B., Geczy, C. (2009). Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes. Atherosclerosis, 202(2), 596-604. [More Information]
  • Medi, C., Kalman, J., Freedman, B. (2009). Supraventricular tachycardia. Medical Journal of Australia, 190(5), 255-260. [More Information]
  • Neubeck, A., Redfern, J., Fernandez, R., Briffa, T., Bauman, A., Freedman, B. (2009). Telehealth interventions for the secondary prevention of coronary heart disease: a systematic review. European Journal of Cardiovascular Prevention and Rehabilitation, 16(3), 281-289. [More Information]

2008

  • Rubboli, A., Halperin, J., Airaksinen, K., Buerke, M., Eeckhout, E., Freedman, B., Gershlick, A., Schlitt, A., Tse, H., Verheugt, F., et al (2008). Antithrombotic therapy in patients treated with oral anticoagulation undergoing coronary artery stenting. An expert consensus document with focus on atrial fibrillation. Annals of Medicine, 40(6), 428-36. [More Information]
  • Redfern, J., Briffa, T., Ellis, E., Freedman, B. (2008). Choice of secondary prevention improves risk factors after acute coronary syndrome: one year follow-up of the CHOICE (Choice of Health Options In prevention of Cardiovascular Events) randomised controlled trial. Heart, Published Online: doi:10.1136/hrt.2008.150870, 1-17. [More Information]
  • Ng, A., Sindone, A., Wong, H., Freedman, B. (2008). Differences in management and outcome of ischemic and non-ischemic cardiomyopathy. International Journal of Cardiology, 129, 198-204. [More Information]
  • Neubeck, A., Menzies, M., Redfern, J., Briffa, T., Freedman, B. (2008). Impact of medical consultation frequency on charge in risk factors after acute coronary syndrome. 16th Annual Cardiovascular Health and Rehabilitation Association State Conference 2008 NSW/ACT, Canberra, Australian Capital Territory, Australia.
  • Ng, A., Chow, C., Wong, H., Sindone, A., Davis, G., Freedman, B. (2008). Impact of sleep disordered breathing severity on the hemodynamics, functional status and autonomic function of chronic heart failure patients. 4th Asian Pacific Congress of Heart Failure 2008, Australia: Elsevier.
  • Fox, K., Ford, I., Steg, P., Tendera, M., Ferrari, R., Freedman, B., Tofler, G. (2008). Ivabridine for patients with stable coronary artery disease and left-ventricular systolic function (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. The Lancet, 372(9641), 807-816. [More Information]
  • Chung, T., Sindone, A., Freedman, B. (2008). Letter by Chung et al regarding article, N-terminal pro B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure: primary results of the Canadian Prospective Randomized Multicenter IMPROVE-CHF study".". Circulation (Baltimore), 117(1), e5; author reply e6. [More Information]
  • Dwyer, J., Redfern, J., Freedman, B. (2008). Low utilisation of cardiovascular risk reducing therapy in patients with acute coronary syndromes and non-obstructive coronary artery disease. International Journal of Cardiology, 129, 394-398. [More Information]
  • Page Mitchell, S., Birden, H., Hudson, J., Thistlethwaite, J., Roberts, C., Wilson, I., Bushnell, J., Hogg, J., Freedman, B., Yeomans, N. (2008). Medical schools can cooperate: A new joint venture to provide medical education in the Northern Rivers Region of New South Wales. Medical Journal of Australia, 188(3), 179-181. [More Information]
  • Redfern, J., Briffa, T., Ellis, E., Freedman, B. (2008). Patient-centered modular secondary prevention following acute coronary syndrome: a randomized controlled trial. Journal of Cardiopulmonary Rehabilitation and Prevention, 28, 107-115. [More Information]
  • Witting, P., Zeng, B., Wong, M., McMahon, A., Rayner, B., Sapir, A., Lowe, H., Freedman, B., Brieger, D. (2008). Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice. Thrombosis Research, 122(5), 674-682. [More Information]
  • Emmett, L., Van Gaal, W., Magee, M., Bass, S., Ali, O., Freedman, B., Van Der Wall, H., Kritharides, L. (2008). Prospective evaluation of the impact of diabetes and left ventricular hypertrophy on the relationship between ischemia and transient ischemic dilation of the left ventricle on single-day adenosine Tc-99m myocardial perfusion imaging. Journal of Nuclear Cardiology, 15(5), 638-643. [More Information]
  • Ng, A., Freedman, B. (2008). Sleep disordered breathing in chronic heart failure. Heart Failure Reviews, DOI 10.1007/s10741-008-9096-8, 1-11. [More Information]
  • Neubeck, A., Redfern, J., Briffa, T., Bauman, A., Hare, D., Freedman, B. (2008). The CHOICE (Choice of Health Options In prevention of Cardiovascular Events) replication trial: study protocol. BMC Cardiovascular Disorders, 8(25), 25-1-25-7. [More Information]
  • Lowe, H., Freedman, B. (2008). The late open artery hypothesis: the case and the artery remain closed. European heart journal, 30, 129-30. [More Information]

2007

  • Ng, A., Chow, C., Wong, H., Sindone, A., Davis, G., Freedman, B. (2007). Anthropometric Characteristics of Patients With Chronic Heart Failure and Severe Sleep Disordered Breathing. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.
  • Medi, C., Hankey, G., Freedman, B. (2007). Atrial fibrillation. Medical Journal of Australia, 186(4), 197-202. [More Information]
  • Ng, A., Freedman, B., Sindone, A. (2007). Autonomic abnormalities in congestive heart failure patients with sleep-disordered breathing. Journal of Cardiac Failure, 13(5), 395-400. [More Information]
  • Ng, A., Davis, G., Chow, C., Wong, H., Sindone, A., Freedman, B. (2007). Chronic Heart Failure Patients With Sleep Disordered Breathing: Functional Assessment and Response to Exercise. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2007). High risk-factor level and low risk-factor knowledge in patients not accessing cardiac rehabilitation after acute coronary syndrome. Medical Journal of Australia, 186(1), 21-25. [More Information]
  • Cai, H., Song, C., Endoh, I., Goyette, J., Jessup, W., Freedman, B., McNeil, H., Geczy, C. (2007). Serum amyloid A induces monocyte tissue factor. Journal of Immunology, 178(3), 1852-1860. [More Information]
  • Ng, A., Davis, G., Chow, C., Wong, H., Sindone, A., Freedman, B. (2007). Severity of Sleep Disordered Breathing (SDB) is Associated with Altered Heart Rate Variability (HRV) in Chronic Heart Failure. 12th Congress of the Asian Pacific Society of Respirology APSR 2007, Australia: Wiley-Blackwell Publishing.

2006

  • Song, C., Nakagomi, A., Chandar, S., Cai, H., Lim, I., McNeil, H., Freedman, B., Geczy, C. (2006). C-reactive protein contributes to the hypercoagulable state in coronary artery disease. Journal of Thrombosis and Haemostasis, 4(1), 98-106. [More Information]
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2006). Development and testing of innovative patient resources for the management of coronary heart disease (CHD): a descriptive study. BMC Health Services Research, 6, 95-1-95-9. [More Information]
  • Lau, G., Ridley, L., Bannon, P., Freedman, B., Brieger, D., Sullivan, D., Wong, L., Kritharides, L. (2006). Hypertriglyceridaemia is associated with early non-patency of coronary bypass grafts. Heart, 92(4), 536-538. [More Information]
  • Chung, T., Sindone, A., Foo, F., Dwyer, A., Paoloni, R., Janu, M., Wong, H., Hall, J., Freedman, B. (2006). Influence of history of heart failure on diagnostic performance and utility of B-type natriuretic peptide testing for acute dyspnea in the emergency department. American Heart Journal, 152(5), 949-955. [More Information]
  • Lau, G., Ridley, L., Bannon, P., Wong, L., Trieu, J., Brieger, D., Lowe, H., Freedman, B., Kritharides, L. (2006). Lumen loss in the first year in saphenous vein grafts is predominantly a result of negative remodeling of the whole vessel rather than a result of changes in wall thickness. Circulation, 114(1), I435-I440. [More Information]
  • Redfern, J., Ellis, E., Briffa, T., Freedman, B. (2006). Modular prevention of heart disease following acute coronary syndrome (ACS) [ISRCTN42984084]. BMC Cardiovascular Disorders, 6(26), 1. [More Information]
  • Prasan, A., Bhagwandeen, R., Solanki, V., Freedman, B., Brieger, D. (2006). Serial Angiography in Patients with Acute Coronary Syndromes: Effect of Antithrombotic Therapy on Angiographic Lesion Severity. Heart, Lung and Circulation, 15(6), 378-382. [More Information]
  • Lowe, H., Freedman, B. (2006). What do we know about perioperative ischaemic cardiac events in patients undergoing non-cardiac surgery? Medical Journal of Australia, 184(8), 376-377.

2005

  • Lau, G., Ridley, L., Schieb, M., Brieger, D., Freedman, B., Wong, L., Lo, S., Kritharides, L. (2005). Coronary artery stenoses: detection with calcium scoring, CT angiography, and both methods combined. Radiology, 235(2), 415-422. [More Information]
  • Briffa, T., Eckermann, S., Griffiths, A., Harris, P., Heath, M., Freedman, B., Donaldson, L., Briffa, N., Keech, A. (2005). Cost-effectiveness of rehabilitation after an acute coronary event: a randomised controlled trial. Medical Journal of Australia, 183(9), 450-455. [More Information]
  • Zeng, B., Prasan, A., Fung, K., Solanki, V., Bruce, D., Freedman, B., Brieger, D. (2005). Elevated circulating levels of matrix metalloproteinase-9 and -2 in patients with symptomatic coronary artery disease. Internal Medicine Journal, 35(6). [More Information]
  • Emmett, L., Magee, M., Freedman, B., Van Der Wall, H., Bush, V., Trieu, J., Van Gaal, W., Allman, K., Kritharides, L. (2005). The role of left ventricular hypertrophy and diabetes in the presence of transient ischemic dilation of the left ventricle on myocardial perfusion SPECT images. The Journal of Nuclear Medicine, 46(10), 1596-1601. [More Information]
  • Kritharides, L., Brieger, D., Freedman, B., Lowe, H. (2005). Treatment of vulnerable plaques: current and future strategies. In Levon Michael Khachigian (Eds.), High-risk atherosclerotic plaques: mechanisms, imaging, models, and therapy, (pp. 161-202). USA: CRC Press.

2004

  • Allman, K., Freedman, B. (2004). Emergency department assessment of patients with acute chest pain: myocardial perfusion imaging, blood tests, or both? Journal of Nuclear Cardiology, 11(1), 87-89.
  • Tiong, A., Freedman, B. (2004). Gene Therapy For Cardiovascular Disease: The Potential Of VEGF. Current Opinion in Molecular Therapeutics, 6(2), 151-159.
  • Lau, G., Brieger, D., Freedman, B. (2004). Infarction due to right coronary artery thrombus. Clinical Cardiology (Hoboken): an indexed and peer-reviewed journal for advances in the treatment of cardiovascular disease, 27(2), 96-96.
  • Allman, K., Freedman, B., Beller, G. (2004). Prognosis In Patients With Known Or Suspected Coronary Artery Disease. In Peter J. Ell & Sanjiv Sam Gambhir (Eds.), Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed, (pp. 1131-1148). Edinburgh: Churchill Livingstone.
  • Beltrame, J., Turner, S., Leslie, S., Solomon, P., Freedman, B., Horowitz, J. (2004). The Angiographic And Clinical Benefits Of Mibefradil In The Coronary Slow Flow Phenomenon. Journal of the American College of Cardiology, 44(1), 57-62. [More Information]

2003

  • Pepine, C., Rouleau, J., Annis, K., Ducharme, A., Ma, P., Lenis, J., Davies, R., Thadani, U., Chaitman, B., Haber, H., Freedman, B., et al (2003). Effects of Angiotensin-converting enzyme inhibition on transient ischemia: The Quinapril anti-ischemia and symptoms of angina reduction (QUASAR) Trial. Journal of the American College of Cardiology, 42(12), 2049-2059. [More Information]
  • Freedman, B., Isner, J. (2003). Therapeutic angiogenesis for coronary artery disease. In Vossoughi, Kipshidze, Moses, Karanian (Eds.), Angiogenesis: Bench to Bedside, (pp. 3-40). Korea: Medical and Engineering Publishers, Inc.

2002

  • Freedman, B. (2002). Clinical trials of gene therapy for atherosclerotic cardiovascular disease. Current Opinion in Lipidology, 13(6), 653-661.
  • Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, , 473-475.
  • Zeng, B., Bruce, D., Kril, J., Ploplis, V., Freedman, B., Brieger, D. (2002). Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis. Thrombosis and Haemostasis, 88, 805-810.
  • Brieger, D., Solanki, V., Gaynor, M., Booth, V., MacDonald, R., Freedman, B. (2002). Optimal strategy for administering Enoxaparin to patients undergoing coronary angiography without angioplasty for acute coronary syndromes. The American Journal of Cardiology, 89(10), 1167-1170.
  • Freedman, B., Vale, P., Kalka, C., Kearney, M., Pieczek, A., Symes, J., Losordo, D., Isner, J. (2002). Plasma vascular endothelial growth factor (VEGF) levels after intramuscular and intramyocardial gene transfer of VEGF-1 plasmid DNA. Human Gene Therapy, 13(13), 1595-1603.
  • Freedman, B., Isner, J. (2002). Therapeutic angiogenesis for coronary artery disease. Annals of Internal Medicine, , 54-71.

2001

  • Freedman, B. (2001). Cytomegalovirus seropositivity and C-reactive protein have indepent and combined prognostic predictive value for mortality in patients with angiographically demonstrated coronary artery disease. Circulation.
  • Freedman, B., Isner,, J. (2001). Therapeutic angiogenesis for coronary artery disease. In LH Opie, DM Yellon (Eds.), Cardiology at the Limits IV, (pp. 129-158). Cape Town, South Africa: Sage Publications.
  • Freedman, B., Isner,, J. (2001). Therapeutic angiogenesis for ischemic cardiovascular disease. Journal of Molecular and Cellular Cardiology, 33, 379-393.
  • Freedman, B. (2001). Tremor-induced ECG artifact mimicking ventricular tachycardia. Circulation.

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