Dr Carolyn Scott

Conjoint Senior Lecturer
Northern Clinical School
Kolling Institute of Medical Research

Telephone +61 2 9926 4712
Fax +61 2 9926 5708

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Selected grants

2008

  • The role of the M6P/IGF-11 receptor in regulating cellular function; Scott C, Firth S; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • The role of the M6P/IGFII receptor in regulating cellular function; Scott C; University of Sydney/Bridging Support.

2006

  • FAXSCalibur 4 -colour Flow Cytometer; Baxter R, Firth S, Marsh D, Schedlich L, Scott C, Martin J, Robinson B; Cancer Institute New South Wales/Research Grants Program - Category 2.

2005

  • Cancer InstNSW Fell05-Scott; Scott C; Cancer Institute New South Wales/Research Grant.
  • Role of a soluble receptor in regulating proliferation in Breast Cancer.; Scott C, Leong G; National Breast Cancer Foundation/Kathleen Cuningham Research Grant.

2000

  • Involvement of IGF-11/mannos 6-P receptor and M6P proteins in hormone dependent cancers; Scott C; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Martin, J., de Silva, H., Lin, Z., Scott, C., Baxter, R. (2014). Inhibition of insulin-like growth factor binding protein-3 signaling through sphingosine kinase 1 sensitizes triple-negative breast cancer cells to EGF receptor blockade. Molecular Cancer Therapeutics, 13(2), 316-328. [More Information]
  • Caixeiro, N., Martin, J., Scott, C. (2013). Silencing the mannose 6-phosphate/IGF-II receptor differentially affects tumorigenic properties of normal breast epithelial cells. International Journal of Cancer, 133(11), 2542-2550. [More Information]
  • Amritraj, A., Hawkes, C., Phinney, A., Mount, H., Scott, C., Westaway, D., Kar, S. (2007). Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+PS1 transgenic mouse brains. Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, doi:10.1016/j.neurobiolaging.2007.05.004(doi:10.1016/j.neurobiolaging.2007.05.004), 1-17. [More Information]
  • Heinzelmann-Schwarz, V., Gardiner-Garden, M., Henshall, S., Scurry, J., Scolyer, R., Smith, A., Bali, A., Vanden Bergh, P., Baron-Hay, S., Scott, C., et al (2006). A distinct molecular profile associated with mucinous epithelial ovarian cancer. British Journal of Cancer, 94(6), 904-913. [More Information]
  • Heinzelmann-Schwarz, V., Scolyer, R., Scurry, J., Smith, A., Gardiner-Garden, M., Biankin, A., Baron-Hay, S., Scott, C., Ward, R., Fink, D., et al (2006). Low meprin alpha expression differentiates primary ovarian mucinous carcinoma from gastrointestinal cancers that commonly metastasise to the ovaries. Journal of Clinical Pathology, 60(6), 622-626. [More Information]
  • Petry, C., Ong, K., Wingate, D., Brown, J., Scott, C., Jones, Y., Pembrey, M., Dunger, D. (2005). Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in childhood height. Growth Hormone and IGF Research, 15(6), 363-368. [More Information]
  • Lee, J., Weiss, J., Martin, J., Scott, C. (2003). Increased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in breast cancer cells alters tumorigenic properties in vitro and in vivo. International Journal of Cancer, 107(4), 564-570. [More Information]
  • Cianfarani, S., Geremia, C., Scott, C., Germani, D. (2002). Growth, IGF System, and Cortisol in Children with Intrauterine Growth Retardation: Is Catch-up Growth Affected by Reprogramming of the Hypothalamic-Pituitary-Adrenal Axis? Pediatric Research: international journal of human developmental biology, 51(1), 94-99.
  • O'Gorman, D., Weiss, J., Firth, S., Hettiaratchi, A., Scott, C. (2002). Insulin-like Growth Factor-II/Mannose 6-Phosphate Receptor Overexpression Reduces Growth of Choriocarcinoma Cells in Vitro and in Vivo. Endocrinology, 143(11), 4287-4294.
  • Delhanty, P., Scott, C., Baxter, R., Babu,, S. (2001). Acid-labile subunit regulation during the early stages of liver regeneration: implications for glucoregulation. American Journal of Physiology: Endocrinology and Metabolism, 280.
  • Scott, C., Cianfarani, S., Geremia, C., Germani, D. (2001). Growth, IGF system, and cortisol in children with intrauterine growth retardation: is catch-up growth affected by reprogramming of the hypothalamic-pituitary-adrenal axis? Pediatric Research: international journal of human developmental biology, 51, 94-99.

2014

  • Martin, J., de Silva, H., Lin, Z., Scott, C., Baxter, R. (2014). Inhibition of insulin-like growth factor binding protein-3 signaling through sphingosine kinase 1 sensitizes triple-negative breast cancer cells to EGF receptor blockade. Molecular Cancer Therapeutics, 13(2), 316-328. [More Information]

2013

  • Caixeiro, N., Martin, J., Scott, C. (2013). Silencing the mannose 6-phosphate/IGF-II receptor differentially affects tumorigenic properties of normal breast epithelial cells. International Journal of Cancer, 133(11), 2542-2550. [More Information]

2007

  • Amritraj, A., Hawkes, C., Phinney, A., Mount, H., Scott, C., Westaway, D., Kar, S. (2007). Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+PS1 transgenic mouse brains. Neurobiology of Aging: age-related phenomena, neurodegeneration and neuropathology, doi:10.1016/j.neurobiolaging.2007.05.004(doi:10.1016/j.neurobiolaging.2007.05.004), 1-17. [More Information]

2006

  • Heinzelmann-Schwarz, V., Gardiner-Garden, M., Henshall, S., Scurry, J., Scolyer, R., Smith, A., Bali, A., Vanden Bergh, P., Baron-Hay, S., Scott, C., et al (2006). A distinct molecular profile associated with mucinous epithelial ovarian cancer. British Journal of Cancer, 94(6), 904-913. [More Information]
  • Heinzelmann-Schwarz, V., Scolyer, R., Scurry, J., Smith, A., Gardiner-Garden, M., Biankin, A., Baron-Hay, S., Scott, C., Ward, R., Fink, D., et al (2006). Low meprin alpha expression differentiates primary ovarian mucinous carcinoma from gastrointestinal cancers that commonly metastasise to the ovaries. Journal of Clinical Pathology, 60(6), 622-626. [More Information]

2005

  • Petry, C., Ong, K., Wingate, D., Brown, J., Scott, C., Jones, Y., Pembrey, M., Dunger, D. (2005). Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in childhood height. Growth Hormone and IGF Research, 15(6), 363-368. [More Information]

2003

  • Lee, J., Weiss, J., Martin, J., Scott, C. (2003). Increased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in breast cancer cells alters tumorigenic properties in vitro and in vivo. International Journal of Cancer, 107(4), 564-570. [More Information]

2002

  • Cianfarani, S., Geremia, C., Scott, C., Germani, D. (2002). Growth, IGF System, and Cortisol in Children with Intrauterine Growth Retardation: Is Catch-up Growth Affected by Reprogramming of the Hypothalamic-Pituitary-Adrenal Axis? Pediatric Research: international journal of human developmental biology, 51(1), 94-99.
  • O'Gorman, D., Weiss, J., Firth, S., Hettiaratchi, A., Scott, C. (2002). Insulin-like Growth Factor-II/Mannose 6-Phosphate Receptor Overexpression Reduces Growth of Choriocarcinoma Cells in Vitro and in Vivo. Endocrinology, 143(11), 4287-4294.

2001

  • Delhanty, P., Scott, C., Baxter, R., Babu,, S. (2001). Acid-labile subunit regulation during the early stages of liver regeneration: implications for glucoregulation. American Journal of Physiology: Endocrinology and Metabolism, 280.
  • Scott, C., Cianfarani, S., Geremia, C., Germani, D. (2001). Growth, IGF system, and cortisol in children with intrauterine growth retardation: is catch-up growth affected by reprogramming of the hypothalamic-pituitary-adrenal axis? Pediatric Research: international journal of human developmental biology, 51, 94-99.

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