Dr Charmaine Tam

PhD
Fellow in Health Informatics

Member of the Charles Perkins Centre

Telephone 02 9515 5183

Website Northern Clinical School
Centre for Translational Data Science

Map

Biographical details

Charmaine Tam is a Fellow in Health Informatics at Northern Clinical School and the Centre for Translational Data Science, the University of Sydney. Her research focuses on liberating, integrating and extracting meaningful information from the growing collection of electronic medical records. The value of this data is realised only when this information is converted into knowledge which enables improvements in patient health outcomes, health care efficiency and minimises low value care. Charmaine works at the much needed interface between health domain experts and data engineers and scientists, ensuring that insights from the burgeoning amount of digital health data are best utilised to lead to improvements in human health within appropriate governance and privacy safeguards.

Charmaine completed her PhD at The Children's Hospital at Westmead on adipose tissue biology in children under the direction of Professor Louise Baur and Professor Karine Clement (Les Cordeliers, INSERM, Paris). Next, she completed her postdoctoral studies at the Pennington Biomedical Research Centrein Baton Rouge, Louisiana under the direction of Professor Eric Ravussin, a world expert in translational studies in obesity and type 2 diabetes. Whilst at the Pennington, Charmaine developed expertise in a range of clinical techniques for examining obesity and diabetes in humans including hyperinsulinemic-euglycemic clamps, adipose tissue and skeletal muscle biopsies and methods of measuring energy expenditure (metabolic cart and whole room calorimetry). In 2012, Charmaine joined the University of Sydney where she was the recipient of a NHMRC Early Career Fellowship. In 2016, Charmaine was awarded the Young Investigator Award by the Australian and New Zealand Society for the study of Obesity for her work investigating the physiological mechanisms contributing to obesity and its metabolic complications.

Research interests

Imagine a world where you walk into your doctor’s office and the treatment you receive is designed by an algorithm tailored to your personal medical history and genetic predisposition. Your doctor already knows which treatment your body will best respond to and potential side effects with particular medications. Pivotal to this change is the liberation and integration of data captured in electronic medical records. This is coupled with the ability to turn vast amounts of information into knowledge and insights that can transform clinical care and improve patient’s health outcomes.

Having developed strong expertise in understanding physiological mechanisms that contribute to obesity and its metabolic complications, my focus in recent years has shifted to digital health. My strong foundation in clinical research studies together with my determination to learn programming skills propelled me into the field of healthcare analytics. My research focuses on harnessing this information, whether it be numbers, text or images, to improve patient health outcomes and reduce unnecessary care. The ultimate aim of my research is to harness data to deliver the best health care to the right person at the right time.

Current research students

Project title Research student
Effects of metabolic stress and exercise on the skeletal muscle structure and function. Sergio MARTINEZ HUENCHULLAN

Current projects

  1. Liberating, integrating and analysing data within electronic medical records from patients presenting with suspected acute coronary syndrome to facilities within Sydney Health Partner Facilities
  2. Analysing electronic medical records to investigate the feasibility of implementing a clinical decision rule for paediatric oncology patients presenting with febrile neutropenia to reduce length of stay in hospital
  3. Investigating the appropriateness of pathology testing for Type 2 diabetes in primary care in Australia
  4. Examining the effects of yo-yo dieting on whole-body and adipose tissue metabolism in obese women
  5. Understanding the sociological factors contributing to the necessary enablers and drivers that bring together high performing teams in data analytics

Associations

  • Health Informatics Society of Australia

Awards and honours

  • 2016: Young Investigator Award for the Australian and New Zealand Society for the Study of Obesity
  • 2012: NHMRC Early Career Fellowship

Selected grants

2018

  • Electronic Data on STEMI Patients (Stage 1); Tam C, Morris J; NSW Health - The Health Administration Corporation/Research Support Program.
  • Using big data to improve health efficiency and reduce low-value care: An exploratory study using pathology testing; Tam C; Sydney Medical School/Kickstart Grant.

2016

  • Does yo-yo dieting have detrimental effects on whole-body and fat tissue metabolism?; Tam C; Rebecca L Cooper Medical Research Foundation/Research Grant.

2013

  • The University of Sydney Core Facility for Human Body Composition Assessment; Salis (nee Sainsbury) A, Caterson I, Brand-Miller J, Simpson S, Tam C, Johnson N, Grunstein R; DVC Research/Equipment Grant.

2012

  • Explorations of protein leverage in humans; Tam C; National Health and Medical Research Council (NHMRC)/Early Career Fellowships.

Selected publications

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Journals

  • Martinez Huenchullan, S., Maharjan, B., Williams, P., Tam, C., McLennan, S., Twigg, S. (2018). Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin. Physiological Reports, 6(4), 1-16. [More Information]
  • Martinez Huenchullan, S., Maharjan, B., Williams, P., Tam, C., McLennan, S., Twigg, S. (2018). Skeletal muscle adiponectin induction depends on diet, muscle type/activity, and exercise modality in C57BL/6 mice. Physiological Reports, 6(19), 1-9. [More Information]
  • Mackie, G., Samocha-Bonet, D., Tam, C. (2017). Does weight cycling promote obesity and metabolic risk factors? Obesity Research & Clinical Practice, 11, 131-139. [More Information]
  • Covington, J., Johannsen, D., Coen, P., Burk, D., Obanda, D., Ebenezer, P., Tam, C., Goodpaster, B., Ravussin, E., Bajpeyi, S. (2017). Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding. Obesity, 25(12), 2079-2087. [More Information]
  • Tam, C. (2017). Reprogramming my career. Science, 357(6346), 102-102. [More Information]
  • Tam, C., Chaudhuri, R., Hutchison, A., Samocha-Bonet, D., Heilbronn, L. (2017). Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans. Metabolism: Clinical and Experimental, 67, 26-30. [More Information]
  • Martinez Huenchullan, S., McLennan, S., Verhoeven, A., Twigg, S., Tam, C. (2017). The emerging role of skeletal muscle extracellular matrix remodelling in obesity and exercise. Obesity Reviews, 18, 776-790. [More Information]
  • Martinez Huenchullan, S., McLennan, S., Ban, L., Morsch, M., Twigg, S., Tam, C. (2017). Utility and reliability of non-invasive muscle function tests in high-fat-fed mice. Experimental Physiology, 102(7), 773-778. [More Information]
  • Tam, C., Rigas, G., Heilbronn, L., Matisan, T., Probst, Y., Talbot, M. (2016). Energy Adaptations Persist 2 Years After Sleeve Gastrectomy and Gastric Bypass. Obesity Surgery, 26, 459-463. [More Information]
  • Tam, C., Redman, L., Greenway, F., LeBlanc, K., Haussmann, M., Ravussin, E. (2016). Energy Metabolic Adaptation and Cardiometabolic Improvements One Year After Gastric Bypass, Sleeve Gastrectomy, and Gastric Band. Journal of Clinical Endocrinology and Metabolism, 101(10), 3755-3764. [More Information]
  • Covington, J., Tam, C., Pasarica, M., Redman, L. (2016). Higher circulating leukocytes in women with PCOS is reversed by aerobic exercise. Biochimie, 124, 27-33. [More Information]
  • Floyd, Z., Gawronska-Kozak, B., Tam, C., Gimble, J. (2016). Mechanisms of metabolism, aging and obesity. Biochimie, 124, 1-2. [More Information]
  • Covington, J., Tam, C., Bajpeyi, S., Galgani, J., Noland, R., Smith, S., Redman, L., Ravussin, E. (2016). Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Medicine and Science in Sports and Exercise, 48(3), 384-390. [More Information]
  • Gosby, A., Lau, N., Tam, C., Iglesias, M., Morrison, C., Caterson, I., Brand-Miller, J., Conigrave, A., Raubenheimer, D., Simpson, S. (2016). Raised FGF-21 and Triglycerides Accompany Increased Energy Intake Driven by Protein Leverage in Lean, Healthy Individuals: A Randomised Trial. PloS One, 11(8), 1-16. [More Information]
  • Song (Wen Chao), W., McLennan, S., Tam, C., Williams, P., Baxter, R., Twigg, S. (2015). CCN2 requires TGF-β signalling to regulate CCAA T/enhancer binding proteins and inhibit fat cell differentiation. Journal of Cell Communication and Signaling, 9(1), 27-36. [More Information]
  • Martin, D., Lee, C., Rigas, G., Tam, C. (2015). Predictors of weight loss 2 years after laparoscopic sleeve gastrectomy. Asian Journal of Endoscopic Surgery, 8, 328-332. [More Information]
  • Tam, C., Power, J., Markovic, T., Yee, C., Morsch, M., McLennan, S., Twigg, S. (2015). The effects of high-fat feeding on physical function and skeletal muscle extracellular matrix. Nutrition and Diabetes, 5, 1-4. [More Information]
  • Tam, C., Power, J., Markovic, T., Yee, C., Morsch, M., McLennan, S., Twigg, S. (2015). The effects of high-fat feeding on physical function and skeletal muscle extracellular matrix. Nutrition and Diabetes, 5(12), 1-4. [More Information]
  • Johannsen, D., Tchoukalova, Y., Tam, C., Covington, J., Xie, W., Schwarz, J., Bajpeyi, S., Ravussin, E. (2014). Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: Testing the "adipose tissue expandability" hypothesis. Diabetes Care, 37(10), 2789-2797. [More Information]
  • Ho, M., Gow, M., Baur, L., Benitez-Aguirre, P., Tam, C., Donaghue, K., Craig, M., Cowell, C., Garnett, S. (2014). Effect of fat loss on arterial elasticity in obese adolescents with clinical insulin resistance: RESIST study. Journal of Clinical Endocrinology and Metabolism, 99(10), E1846-E1853. [More Information]
  • St-Onge, M., Shechter, A., Shlisky, J., Tam, C., Gao, S., Ravussin, E., Butler, A. (2014). Fasting Plasma Adropin Concentrations Correlate with Fat Consumption in Human Females. Obesity, 22(4), 1056-1063. [More Information]
  • Tam, C., Frost, E., Xie, W., Rood, J., Ravussin, E., Redman, L. (2014). No Effect of Caloric Restriction on Salivary Cortisol Levels in Overweight Men and Women. Metabolism: Clinical and Experimental, 63(2), 194-198. [More Information]
  • Samocha-Bonet, D., Tam, C., Campbell, L., Heilbronn, L. (2014). Raised circulating fetuin-a after 28-day overfeeding in healthy humans. Diabetes Care, 37(1), e15-e16. [More Information]
  • Tam, C., Covington, J., Bajpeyi, S., Tchoukalova, Y., Burk, D., Johannsen, D., Zingaretti, C., Cinti, S., Ravussin, E. (2014). Weight Gain Reveals Dramatic Increases in Skeletal Muscle Extracellular Matrix Remodeling. Journal of Clinical Endocrinology and Metabolism, 99(5), 1749-1757. [More Information]
  • Tam, C., Redman, L. (2013). Adipose tissue inflammation and metabolic dysfunction: A clinical perspective. Hormone Molecular Biology and Clinical Investigation, 15(1), 19-24. [More Information]
  • Tam, C., Covington, J., Ravussin, E. (2013). Response to Low Macrophage Content in Diabetic and Aging Human Skeletal Muscle. Obesity, 21(1), 4-5. [More Information]
  • Tam, C., Ravussin, E. (2013). Response to to Comment on: Tam et al. Defining Insulin Resistance from Hyperinsulinemic-Euglycemic Clamps 2012;35:1605-1610. Diabetes Care, 36, e11-e11. [More Information]
  • Tam, C., Tordjman, J., Divoux, A., Baur, L., Clement, K. (2012). Adipose Tissue Remodeling in Children: The Link between Collagen Deposition and Age-Related Adipocyte Growth. Journal of Clinical Endocrinology and Metabolism, 97(4), 1320-1327. [More Information]
  • Tam, C., Lecoultre, V., Ravussin, E. (2012). Brown Adipose Tissue: Mechanisms and Potential Therapeutic Targets. Circulation, 125(22), 2782-2791. [More Information]
  • Tam, C., Xie, W., Johnson, W., Cefalu, W., Redman, L., Ravussin, E. (2012). Defining Insulin Resistance From Hyperinsulinemic-Euglycemic Clamps. Diabetes Care, 35(7), 1605-1610. [More Information]
  • Tam, C., Ravussin, E. (2012). Energy balance: An overview with emphasis on children. Pediatric Blood and Cancer, 58(1), 154-158. [More Information]
  • Lecoultre, V., Tam, C. (2012). Letter by Lecoultre and Tam Regarding Article, “Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation�? Circulation, 125: e315(1), 67-76. [More Information]
  • Tam, C., Covington, J., Ravussin, E., Redman, L. (2012). Little evidence of systemic and adipose tissue inflammation in overweight individuals. Frontiers in Genetics, 3(APR), 1-7. [More Information]
  • Butler, A., Tam, C., Stanhope, K., Wolfe, B., Ali, M., O'Keeffe, M., St-Onge, M., Ravussin, E., Havel, P. (2012). Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans. Journal of Clinical Endocrinology and Metabolism, 97(10), 3783-3791. [More Information]
  • Tam, C., Sparks, L., Johannsen, D., Covington, J., Church, T., Ravussin, E. (2012). Low Macrophage Accumulation in Skeletal Muscle of Obese Type 2 Diabetics and Elderly Subjects. Obesity, 20(7), 1530-1533. [More Information]
  • Tam, C., Heilbronn, L., Henegar, C., Wong, M., Cowell, C., Cowley, M., Kaplan, W., Clement, K., Baur, L. (2011). An early inflammatory gene profile in visceral adipose tissue in children. International Journal of Pediatric Obesity, 6(2-2), e360-e363. [More Information]
  • Tam, C., Berthoud, H., Bueter, M., Chakravarty, M., Geliebter, A., Hajnal, A., Holst, J., Kaplan, L., Pories, W., Raybould, H., et al (2011). Bariatric surgery: do the mechanisms hold the key for novel therapies. Obesity Reviews, 12(11), 984-994. [More Information]
  • Tam, C., Lecoultre, V., Ravussin, E. (2011). Novel strategy for the use of leptin for obesity therapy. Expert Opinion on Biological Therapy, 11(12), 1677-1685. [More Information]
  • Samocha-Bonet, D., Campbell, L., Viardot, A., Freund, J., Tam, C., Greenfield, J., Heilbronn, L. (2010). A family history of type 2 diabetes increases risk factors associated with overfeeding. Diabetologia, 53(8), 1700-1708. [More Information]
  • Tam, C., Garnett, S., Cowell, C., Heilbronn, L., Lee, J., Wong, M., Baur, L. (2010). IL-6, IL-8 and IL-10 levels in healthy weight and overweight children. Hormone Research in Paediatrics, 73(2), 128-134. [More Information]
  • Tam, C., Clement, K., Baur, L., Tordjman, J. (2010). Obesity and low-grade inflammation: a pediatric perspective. Obesity Reviews, 11(2), 118-126. [More Information]
  • Tam, C., Viardot, A., Clement, K., Tordjman, J., Tonks, K., Greenfield, J., Campbell, L., Samocha-Bonet, D., Heilbronn, L. (2010). Short-term overfeeding induces insulin resistance without altering adipose tissue macrophages. Diabetes, 59(9), 2164-2170. [More Information]
  • Waters, K., Mast, B., Vella, S., de la Eva, R., O'Brien, L., Bailey, S., Tam, C., Wong, M., Baur, L. (2007). Structural equation modeling of sleep apnea, inflammation, and metabolic dysfunction in children. Journal of Sleep Research, 16(4), 388-395. [More Information]
  • Tam, C., Wong, M., Tam, K., Aouad, L., Waters, K. (2007). The effect of acute intermittent hypercapnic hypoxia treatment on IL-6, TNF-alpha, and CRP levels in piglets. Sleep, 30(6), 723-727. [More Information]
  • Tam, C., Wong, M., McBain, R., Bailey, S., Waters, K. (2006). Inflammatory measures in children with obstructive sleep apnoea. Journal of Paediatrics and Child Health, 42(5), 277-282. [More Information]
  • Tam, C., de Zegher, F., Garnett, S., Baur, L., Cowell, C. (2006). Opposing Influences of Prenatal and Postnatal Growth on the Timing of Menarche. The Journal of Clinical Endocrinology and Metabolism, 91(11), 4369-4373. [More Information]
  • Tam, C., Garnett, S., Cowell, C., Campbell, K., Cabrera, G., Baur, L. (2006). Soft drink consumption and excess weight gain in Australian school students: results from the Nepean study. International Journal of Obesity, 30(7), 1091-1093. [More Information]

2018

  • Martinez Huenchullan, S., Maharjan, B., Williams, P., Tam, C., McLennan, S., Twigg, S. (2018). Differential metabolic effects of constant moderate versus high intensity interval training in high-fat fed mice: possible role of muscle adiponectin. Physiological Reports, 6(4), 1-16. [More Information]
  • Martinez Huenchullan, S., Maharjan, B., Williams, P., Tam, C., McLennan, S., Twigg, S. (2018). Skeletal muscle adiponectin induction depends on diet, muscle type/activity, and exercise modality in C57BL/6 mice. Physiological Reports, 6(19), 1-9. [More Information]

2017

  • Mackie, G., Samocha-Bonet, D., Tam, C. (2017). Does weight cycling promote obesity and metabolic risk factors? Obesity Research & Clinical Practice, 11, 131-139. [More Information]
  • Covington, J., Johannsen, D., Coen, P., Burk, D., Obanda, D., Ebenezer, P., Tam, C., Goodpaster, B., Ravussin, E., Bajpeyi, S. (2017). Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding. Obesity, 25(12), 2079-2087. [More Information]
  • Tam, C. (2017). Reprogramming my career. Science, 357(6346), 102-102. [More Information]
  • Tam, C., Chaudhuri, R., Hutchison, A., Samocha-Bonet, D., Heilbronn, L. (2017). Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans. Metabolism: Clinical and Experimental, 67, 26-30. [More Information]
  • Martinez Huenchullan, S., McLennan, S., Verhoeven, A., Twigg, S., Tam, C. (2017). The emerging role of skeletal muscle extracellular matrix remodelling in obesity and exercise. Obesity Reviews, 18, 776-790. [More Information]
  • Martinez Huenchullan, S., McLennan, S., Ban, L., Morsch, M., Twigg, S., Tam, C. (2017). Utility and reliability of non-invasive muscle function tests in high-fat-fed mice. Experimental Physiology, 102(7), 773-778. [More Information]

2016

  • Tam, C., Rigas, G., Heilbronn, L., Matisan, T., Probst, Y., Talbot, M. (2016). Energy Adaptations Persist 2 Years After Sleeve Gastrectomy and Gastric Bypass. Obesity Surgery, 26, 459-463. [More Information]
  • Tam, C., Redman, L., Greenway, F., LeBlanc, K., Haussmann, M., Ravussin, E. (2016). Energy Metabolic Adaptation and Cardiometabolic Improvements One Year After Gastric Bypass, Sleeve Gastrectomy, and Gastric Band. Journal of Clinical Endocrinology and Metabolism, 101(10), 3755-3764. [More Information]
  • Covington, J., Tam, C., Pasarica, M., Redman, L. (2016). Higher circulating leukocytes in women with PCOS is reversed by aerobic exercise. Biochimie, 124, 27-33. [More Information]
  • Floyd, Z., Gawronska-Kozak, B., Tam, C., Gimble, J. (2016). Mechanisms of metabolism, aging and obesity. Biochimie, 124, 1-2. [More Information]
  • Covington, J., Tam, C., Bajpeyi, S., Galgani, J., Noland, R., Smith, S., Redman, L., Ravussin, E. (2016). Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Medicine and Science in Sports and Exercise, 48(3), 384-390. [More Information]
  • Gosby, A., Lau, N., Tam, C., Iglesias, M., Morrison, C., Caterson, I., Brand-Miller, J., Conigrave, A., Raubenheimer, D., Simpson, S. (2016). Raised FGF-21 and Triglycerides Accompany Increased Energy Intake Driven by Protein Leverage in Lean, Healthy Individuals: A Randomised Trial. PloS One, 11(8), 1-16. [More Information]

2015

  • Song (Wen Chao), W., McLennan, S., Tam, C., Williams, P., Baxter, R., Twigg, S. (2015). CCN2 requires TGF-β signalling to regulate CCAA T/enhancer binding proteins and inhibit fat cell differentiation. Journal of Cell Communication and Signaling, 9(1), 27-36. [More Information]
  • Martin, D., Lee, C., Rigas, G., Tam, C. (2015). Predictors of weight loss 2 years after laparoscopic sleeve gastrectomy. Asian Journal of Endoscopic Surgery, 8, 328-332. [More Information]
  • Tam, C., Power, J., Markovic, T., Yee, C., Morsch, M., McLennan, S., Twigg, S. (2015). The effects of high-fat feeding on physical function and skeletal muscle extracellular matrix. Nutrition and Diabetes, 5, 1-4. [More Information]
  • Tam, C., Power, J., Markovic, T., Yee, C., Morsch, M., McLennan, S., Twigg, S. (2015). The effects of high-fat feeding on physical function and skeletal muscle extracellular matrix. Nutrition and Diabetes, 5(12), 1-4. [More Information]

2014

  • Johannsen, D., Tchoukalova, Y., Tam, C., Covington, J., Xie, W., Schwarz, J., Bajpeyi, S., Ravussin, E. (2014). Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: Testing the "adipose tissue expandability" hypothesis. Diabetes Care, 37(10), 2789-2797. [More Information]
  • Ho, M., Gow, M., Baur, L., Benitez-Aguirre, P., Tam, C., Donaghue, K., Craig, M., Cowell, C., Garnett, S. (2014). Effect of fat loss on arterial elasticity in obese adolescents with clinical insulin resistance: RESIST study. Journal of Clinical Endocrinology and Metabolism, 99(10), E1846-E1853. [More Information]
  • St-Onge, M., Shechter, A., Shlisky, J., Tam, C., Gao, S., Ravussin, E., Butler, A. (2014). Fasting Plasma Adropin Concentrations Correlate with Fat Consumption in Human Females. Obesity, 22(4), 1056-1063. [More Information]
  • Tam, C., Frost, E., Xie, W., Rood, J., Ravussin, E., Redman, L. (2014). No Effect of Caloric Restriction on Salivary Cortisol Levels in Overweight Men and Women. Metabolism: Clinical and Experimental, 63(2), 194-198. [More Information]
  • Samocha-Bonet, D., Tam, C., Campbell, L., Heilbronn, L. (2014). Raised circulating fetuin-a after 28-day overfeeding in healthy humans. Diabetes Care, 37(1), e15-e16. [More Information]
  • Tam, C., Covington, J., Bajpeyi, S., Tchoukalova, Y., Burk, D., Johannsen, D., Zingaretti, C., Cinti, S., Ravussin, E. (2014). Weight Gain Reveals Dramatic Increases in Skeletal Muscle Extracellular Matrix Remodeling. Journal of Clinical Endocrinology and Metabolism, 99(5), 1749-1757. [More Information]

2013

  • Tam, C., Redman, L. (2013). Adipose tissue inflammation and metabolic dysfunction: A clinical perspective. Hormone Molecular Biology and Clinical Investigation, 15(1), 19-24. [More Information]
  • Tam, C., Covington, J., Ravussin, E. (2013). Response to Low Macrophage Content in Diabetic and Aging Human Skeletal Muscle. Obesity, 21(1), 4-5. [More Information]
  • Tam, C., Ravussin, E. (2013). Response to to Comment on: Tam et al. Defining Insulin Resistance from Hyperinsulinemic-Euglycemic Clamps 2012;35:1605-1610. Diabetes Care, 36, e11-e11. [More Information]

2012

  • Tam, C., Tordjman, J., Divoux, A., Baur, L., Clement, K. (2012). Adipose Tissue Remodeling in Children: The Link between Collagen Deposition and Age-Related Adipocyte Growth. Journal of Clinical Endocrinology and Metabolism, 97(4), 1320-1327. [More Information]
  • Tam, C., Lecoultre, V., Ravussin, E. (2012). Brown Adipose Tissue: Mechanisms and Potential Therapeutic Targets. Circulation, 125(22), 2782-2791. [More Information]
  • Tam, C., Xie, W., Johnson, W., Cefalu, W., Redman, L., Ravussin, E. (2012). Defining Insulin Resistance From Hyperinsulinemic-Euglycemic Clamps. Diabetes Care, 35(7), 1605-1610. [More Information]
  • Tam, C., Ravussin, E. (2012). Energy balance: An overview with emphasis on children. Pediatric Blood and Cancer, 58(1), 154-158. [More Information]
  • Lecoultre, V., Tam, C. (2012). Letter by Lecoultre and Tam Regarding Article, “Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation�? Circulation, 125: e315(1), 67-76. [More Information]
  • Tam, C., Covington, J., Ravussin, E., Redman, L. (2012). Little evidence of systemic and adipose tissue inflammation in overweight individuals. Frontiers in Genetics, 3(APR), 1-7. [More Information]
  • Butler, A., Tam, C., Stanhope, K., Wolfe, B., Ali, M., O'Keeffe, M., St-Onge, M., Ravussin, E., Havel, P. (2012). Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans. Journal of Clinical Endocrinology and Metabolism, 97(10), 3783-3791. [More Information]
  • Tam, C., Sparks, L., Johannsen, D., Covington, J., Church, T., Ravussin, E. (2012). Low Macrophage Accumulation in Skeletal Muscle of Obese Type 2 Diabetics and Elderly Subjects. Obesity, 20(7), 1530-1533. [More Information]

2011

  • Tam, C., Heilbronn, L., Henegar, C., Wong, M., Cowell, C., Cowley, M., Kaplan, W., Clement, K., Baur, L. (2011). An early inflammatory gene profile in visceral adipose tissue in children. International Journal of Pediatric Obesity, 6(2-2), e360-e363. [More Information]
  • Tam, C., Berthoud, H., Bueter, M., Chakravarty, M., Geliebter, A., Hajnal, A., Holst, J., Kaplan, L., Pories, W., Raybould, H., et al (2011). Bariatric surgery: do the mechanisms hold the key for novel therapies. Obesity Reviews, 12(11), 984-994. [More Information]
  • Tam, C., Lecoultre, V., Ravussin, E. (2011). Novel strategy for the use of leptin for obesity therapy. Expert Opinion on Biological Therapy, 11(12), 1677-1685. [More Information]

2010

  • Samocha-Bonet, D., Campbell, L., Viardot, A., Freund, J., Tam, C., Greenfield, J., Heilbronn, L. (2010). A family history of type 2 diabetes increases risk factors associated with overfeeding. Diabetologia, 53(8), 1700-1708. [More Information]
  • Tam, C., Garnett, S., Cowell, C., Heilbronn, L., Lee, J., Wong, M., Baur, L. (2010). IL-6, IL-8 and IL-10 levels in healthy weight and overweight children. Hormone Research in Paediatrics, 73(2), 128-134. [More Information]
  • Tam, C., Clement, K., Baur, L., Tordjman, J. (2010). Obesity and low-grade inflammation: a pediatric perspective. Obesity Reviews, 11(2), 118-126. [More Information]
  • Tam, C., Viardot, A., Clement, K., Tordjman, J., Tonks, K., Greenfield, J., Campbell, L., Samocha-Bonet, D., Heilbronn, L. (2010). Short-term overfeeding induces insulin resistance without altering adipose tissue macrophages. Diabetes, 59(9), 2164-2170. [More Information]

2007

  • Waters, K., Mast, B., Vella, S., de la Eva, R., O'Brien, L., Bailey, S., Tam, C., Wong, M., Baur, L. (2007). Structural equation modeling of sleep apnea, inflammation, and metabolic dysfunction in children. Journal of Sleep Research, 16(4), 388-395. [More Information]
  • Tam, C., Wong, M., Tam, K., Aouad, L., Waters, K. (2007). The effect of acute intermittent hypercapnic hypoxia treatment on IL-6, TNF-alpha, and CRP levels in piglets. Sleep, 30(6), 723-727. [More Information]

2006

  • Tam, C., Wong, M., McBain, R., Bailey, S., Waters, K. (2006). Inflammatory measures in children with obstructive sleep apnoea. Journal of Paediatrics and Child Health, 42(5), 277-282. [More Information]
  • Tam, C., de Zegher, F., Garnett, S., Baur, L., Cowell, C. (2006). Opposing Influences of Prenatal and Postnatal Growth on the Timing of Menarche. The Journal of Clinical Endocrinology and Metabolism, 91(11), 4369-4373. [More Information]
  • Tam, C., Garnett, S., Cowell, C., Campbell, K., Cabrera, G., Baur, L. (2006). Soft drink consumption and excess weight gain in Australian school students: results from the Nepean study. International Journal of Obesity, 30(7), 1091-1093. [More Information]

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