Dr Chi Pham

Postdoctoral Research Associate
Pharmacology, School of Medical Sciences


Map

Selected grants

2010

  • Structural and functional studies of a-synuclein oligomers. University of Melbourne Early Career Research Grant; Pham C; University of Melbourne/Early Career Researcher Development Award.

2009

  • ANSTSO-University of Melbourne Collaborative Research Support Scheme; Pham C; ANSTO/Project Support.

Selected publications

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Journals

  • Pham, C., Cappai, R. (2013). The interplay between lipids and dopamine on α-synuclein oligomerization and membrane binding. Bioscience Reports, 33(5), 807-814. [More Information]
  • Falsone, S., Meyer, N., Schrank, E., Leitinger, G., Pham, C., Fodero-Tavoletti, M., Holmberg, M., Dulle, M., Scicluna, B., Gesslbauer, B., et al (2012). SERF protein is a direct modifier of amyloid fiber assembly. Cell Reports, 2(2), 358-371. [More Information]
  • Spoerri, L., Vella, L., Pham, C., Barnham, K., Cappai, R. (2012). The amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism. Journal of Biological Chemistry, 287(32), 26840-26853. [More Information]
  • Hung, L., Villemagne, V., Cheng, L., Sherratt, N., Ayton, S., White, A., Crouch, P., Lim, S., Leong, S., Wilkins, S., Pham, C., et al (2012). The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. The Journal of Experimental Medicine, 209(4), 837-854. [More Information]
  • Teoh, C., Pham, C., Todorova, N., Hung, A., Lincoln, C., Lees, E., Lam, Y., Binger, K., Thomson, N., Radford, S., et al (2011). A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations. Journal of Molecular Biology, 405(5), 1246-1266. [More Information]
  • Pham, C., Mok, Y., Howlett, G. (2011). Sedimentation Velocity Analysis of Amyloid Fibrils. Methods in Molecular Biology, 752, 179-196. [More Information]
  • Corrigan, F., Pham, C., Vink, R., Blumbergs, P., Masters, C., van den Heuvel, C., Cappai, R. (2011). The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains. Brain Research, 1378, 137-143. [More Information]
  • Banerjee, K., Sinha, M., Pham, C., Jana, S., Chanda, D., Cappai, R., Chakrabarti, S. (2010). (alpha)-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson’s disease. Febs Letters, 584(8), 1571-1576. [More Information]
  • Rekas, A., Knott, R., Sokolova, A., Barnham, K., Perez, K., Masters, C., Drew, S., Cappai, R., Curtain, C., Pham, C. (2010). The structure of dopamine induced (Alpha) synuclein oligomers. European Biophysics Journal, 39, 1407-1419. [More Information]
  • Pham, C., Leong, S., Ali, F., Kenche, V., Hill, A., Gras, S., Barnham, K., Cappai, R. (2009). Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner. Journal of Molecular Biology, 387(3), 771-785. [More Information]
  • Leong, S., Pham, C., Galatis, D., Fodero-Tavoletti, M., Perez, K., Hill, A., Masters, C., Ali, F., Barnham, K., Cappai, R. (2009). Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation. Free Radical Biology and Medicine, 46(10), 1328-1337. [More Information]
  • Leong, S., Cappai, R., Barnham, K., Pham, C. (2009). Modulation of a-Synuclein Aggregation by Dopamine: A Review. Neurochemical Research, 34, 1838-1846. [More Information]
  • Binger, K., Pham, C., Wilson, L., Bailey, M., Lawrence, L., Schuck, P., Howlett, G. (2008). Apolipoprotein C-II Amyloid Fibrils Assemble via a Reversible Pathway that Includes Fibril Breaking and Rejoining. Journal of Molecular Biology, 376(4), 1116-1129. [More Information]
  • Drew, S., Leong, S., Pham, C., Tew, D., Masters, C., Miles, L., Cappai, R., Barnham, K. (2008). Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy. Journal of the American Chemical Society, 130(24), 7766-7773. [More Information]
  • Griffin, M., Mok, M., Wilson, L., Pham, C., Waddington, L., Perugini, M., Howlett, G. (2008). Phospholipid Interaction Induces Molecular-level Polymorphism in Apolipoprotein C-II Amyloid Fibrils via Alternative Assembly Pathways. Journal of Molecular Biology, 375(1), 240-256. [More Information]

2013

  • Pham, C., Cappai, R. (2013). The interplay between lipids and dopamine on α-synuclein oligomerization and membrane binding. Bioscience Reports, 33(5), 807-814. [More Information]

2012

  • Falsone, S., Meyer, N., Schrank, E., Leitinger, G., Pham, C., Fodero-Tavoletti, M., Holmberg, M., Dulle, M., Scicluna, B., Gesslbauer, B., et al (2012). SERF protein is a direct modifier of amyloid fiber assembly. Cell Reports, 2(2), 358-371. [More Information]
  • Spoerri, L., Vella, L., Pham, C., Barnham, K., Cappai, R. (2012). The amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism. Journal of Biological Chemistry, 287(32), 26840-26853. [More Information]
  • Hung, L., Villemagne, V., Cheng, L., Sherratt, N., Ayton, S., White, A., Crouch, P., Lim, S., Leong, S., Wilkins, S., Pham, C., et al (2012). The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. The Journal of Experimental Medicine, 209(4), 837-854. [More Information]

2011

  • Teoh, C., Pham, C., Todorova, N., Hung, A., Lincoln, C., Lees, E., Lam, Y., Binger, K., Thomson, N., Radford, S., et al (2011). A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations. Journal of Molecular Biology, 405(5), 1246-1266. [More Information]
  • Pham, C., Mok, Y., Howlett, G. (2011). Sedimentation Velocity Analysis of Amyloid Fibrils. Methods in Molecular Biology, 752, 179-196. [More Information]
  • Corrigan, F., Pham, C., Vink, R., Blumbergs, P., Masters, C., van den Heuvel, C., Cappai, R. (2011). The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains. Brain Research, 1378, 137-143. [More Information]

2010

  • Banerjee, K., Sinha, M., Pham, C., Jana, S., Chanda, D., Cappai, R., Chakrabarti, S. (2010). (alpha)-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson’s disease. Febs Letters, 584(8), 1571-1576. [More Information]
  • Rekas, A., Knott, R., Sokolova, A., Barnham, K., Perez, K., Masters, C., Drew, S., Cappai, R., Curtain, C., Pham, C. (2010). The structure of dopamine induced (Alpha) synuclein oligomers. European Biophysics Journal, 39, 1407-1419. [More Information]

2009

  • Pham, C., Leong, S., Ali, F., Kenche, V., Hill, A., Gras, S., Barnham, K., Cappai, R. (2009). Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner. Journal of Molecular Biology, 387(3), 771-785. [More Information]
  • Leong, S., Pham, C., Galatis, D., Fodero-Tavoletti, M., Perez, K., Hill, A., Masters, C., Ali, F., Barnham, K., Cappai, R. (2009). Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation. Free Radical Biology and Medicine, 46(10), 1328-1337. [More Information]
  • Leong, S., Cappai, R., Barnham, K., Pham, C. (2009). Modulation of a-Synuclein Aggregation by Dopamine: A Review. Neurochemical Research, 34, 1838-1846. [More Information]

2008

  • Binger, K., Pham, C., Wilson, L., Bailey, M., Lawrence, L., Schuck, P., Howlett, G. (2008). Apolipoprotein C-II Amyloid Fibrils Assemble via a Reversible Pathway that Includes Fibril Breaking and Rejoining. Journal of Molecular Biology, 376(4), 1116-1129. [More Information]
  • Drew, S., Leong, S., Pham, C., Tew, D., Masters, C., Miles, L., Cappai, R., Barnham, K. (2008). Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy. Journal of the American Chemical Society, 130(24), 7766-7773. [More Information]
  • Griffin, M., Mok, M., Wilson, L., Pham, C., Waddington, L., Perugini, M., Howlett, G. (2008). Phospholipid Interaction Induces Molecular-level Polymorphism in Apolipoprotein C-II Amyloid Fibrils via Alternative Assembly Pathways. Journal of Molecular Biology, 375(1), 240-256. [More Information]

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