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Professor Cindy (Shin-Yi) Lin

PhD MEngSci(Biomedical) BE(EngSci)
The Kam Ling Barbara Lo Chair in Neurodegenerative Disorders, Central Clinical School / Brain and Mind Centre

Member of the Brain and Mind Centre

Telephone +61 291144035

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Biographical details

Professor Cindy (Shin-Yi) Lin is the inaugural Kam Ling Barbara Lo Chair in Neurodegenerative Disorders at the University of Sydney, Central Clinical School, Faculty of Medicine and Health and member of the Brain and Mind Centre. This chair was created by the successful high-impact philanthropic support to the University of Sydney.

Professor Lin has qualifications in Biomedical Engineering, obtaining a Bachelor degree in Engineering Science, Auckland University; Master of Engineering Science from the Graduate School of Biomedical Engineering at the University of New South Wales. Professor Lin has further developed her career from Engineering to the clinical realm. She has completed her PhD in Neurosciences under faculty of Medicine at University of New South Wales. She was awarded the NHMRC CJ Martin travelling Fellowship to study postdoctoral at the Sobell Department of Motor Neuroscience and Movement Disorders at the Institute of Neurology, Queen Square, University College London, UK.

Professor Lin specializes in neurophysiological techniques, particularly threshold tracking and adapting these novel techniques to the clinical setting. She is heavily involved in the development of clinical biomarkers that can be used in the diagnosis of patients with neurological disease and in clinical trials of new therapies across a spectrum of neurodegenerative disorders. Professor Lin is actively involved in international multidisciplinary research, directed to the clinical translation of basic science physiology through to the interpretation and treatment of patients with neurological disease. Professor Lin has experiences across a wide range of neurodegenerative diseases, not just in one single disease, her work covers the full age spectrum from Pediatrics to ageing population. She has published her work in the highest-impact international multidisciplinary journals incorporating the fields of Clinical Neurology, Oncology and Endocrinology.

Professor Lin has established national and international recognition in research grants, publications, and collaborations. Within Australia, with the Sydney Children’s Hospital, Neurology, Oncology at Prince of Wales Hospital. Professor Lin’s international standing is reflected in her international collaborations include the National Hospital for Neurology and Neurosurgery, Institute of Neurology (IoN), University College London (UCL), UK, the Department of Neurology, Department of Neurology Chiba University Hospital, Japan, and National Taiwan University Hospital (NTUH), Taipei Medical University (TMU) and Wang Fang Hospital, Taiwan. Professor Lin has been involved in all aspects of neurodegenerative diseases throughout her research career - whether the degeneration of nerve cells or brain regions is caused by chemotherapy, inflammatory conditions, diabetes, genetic mutations or some other insults.

Her role is to ‘bridge the gap’ between multidisciplinary research across the clinical neurosciences from children, adolescents to the aging population, with her unique background in biomedical engineering combined with training in neuroscience and clinical research, to improve research outcomes and facilitate the translation of research innovations directly into clinical practice for the benefit of patients and the community and to translate ‘bench to bedside’ research into tangible outcomes nationally and internationally.

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Research interests

  • Assessment of pathophysiology and development in Paediatric genetic mutation/neuropathies (Spinal Muscular Atrophy SMA)
  • Diabetic neuropathies (Type 1 and Type 2)
  • Immune-mediated inflammatory neuropathies (AIDP, CIDP, MMN)
  • Genetic Neuropathies (Porphyria, Erythromelalgia, Farbry’s Diseases)
  • Clinical neurophysiology & nerve excitability
  • Clinical Translation/Biomarkers
  • Neurodegeneration (MND, SMA)
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Teaching and supervision

Professor Lin has a strong interest in neuroscience/medicine education, lectured to both Medical and Medical Science students in Muscle and Motor Control, Fundamentals of Neuroscience and Neuromuscular rehabilitation, Ageing and Ending. Professor Lin has also trained a number of neurologists and neuroscientists on nerve excitability techniques at various institutes worldwide.

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Current projects

  • Novel Strategies for the management of neuromuscular disease: The pathway from diagnosis to treatment - Dr Didu Sanduni Thamarasa, Kariyawasam (PhD candidate, paediatric Neurologist, Sydney Children’s Hospital)
  • The assessment of pathophysiology and developing outcome measures in spinal muscular atrophy (SMA)/paediatric neuropathies – Associate Professor/Dr Michelle Farrar

Progression of diabetic neuropathy from pathophysiologic, symptomatologic, and nerve excitability viewpoints.

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Associations

CSL BEHRING CONSULTANT

  • Research on immunotherapy: Intraveneous immunoglobulin (IVIg) has attracted CSL Behring to the Interlaken leadership award(2012)
  • Successfully established a consultancy with CSL Behring for future trials
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Professor Lin is a Web Editor for the Journal of Neurology, Neurosurgery and Psychiatry JNNP

Prof Lin has led a number of clinical excitability workshops to further the education and implementation of axonal excitability techniques internationally. In 2009 she was invited to host the inaugural Excitability Workshop at the Institute of Neurology, UCL, U.K., followed in 2010 by the Threshold Tracking Workshop at the International Congress of Clinical Neurophysiology, Kobe, Japan on behalf of the International Federation of Clinical Neurology. Further, she was involved in the Upper Limb in Spinal Cord Injury Workshop, at the 7th World Congress Neurorehabilitation in Melbourne 2012.

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International links

Japan

(Chiba Hospital, Chiba University, Chiba) Department of Neurology

Taiwan

(National Taiwan University & Hospital, Taipei) Department of Neurology

Taiwan

(Wan Fang Hospital, Taipei Medical University, Taipei) Department of Neurology

United Kingdom

(Institute of Neurology, University College London (UCL)) The Sobell Department of Motor Neuroscience and Movement Disorders

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Selected grants

2018

  • Mathematical modelling in neurodegenerative diseases; Kiernan M, Lin C; Sydney Medical School Foundation/Foundation Grant.
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Selected publications

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Book Chapters

  • Park, S., Lin, C., Kiernan, M. (2016). Axonal excitability: molecular basis and assessment in the clinic. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 97-105). Oxford: Oxford University Press.
  • Lin, C., Park, S., Krishnan, A. (2013). Porphyric neuropathy. In Gerard Said and Christian Krarup (Eds.), Handbook of Clinical Neurology: Vol 115 Peripheral Nerve Disorders, (pp. 613-627). Amsterdam: Elsevier. [More Information]
  • Kiernan, M., Lin, C. (2012). Nerve excitability: a clinical translation. In Michael J. Aminoff (Eds.), Aminoffs Electrodiagnosis in Clinical Neurology, (pp. 345-365). China: Saunders Elsevier. [More Information]

Journals

  • Kandula, T., Farrar, M., Krishnan, A., Murray, J., Timmins, H., Goldstein, D., Lin, C., Kiernan, M., Park, S. (2018). Multimodal quantitative examination of nerve function in colorectal cancer patients prior to chemotherapy. Muscle and Nerve, 57(4), 615-621. [More Information]
  • Mathey, E., Garg, N., Park, S., Nguyen, T., Baker, S., Yuki, N., Yiannikas, K., Lin, C., Spies, J., Ghaoui, R., Barnett, M., Vucic, S., Pollard, J., Kiernan, M. (2017). Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies. Journal of Neuroimmunology, 309, 41-46. [More Information]
  • Farrar, M., Lee, M., Howells, J., Andrews, P., Lin, C. (2017). Burning pain: axonal dysfunction in erythromelalgia. Pain, 158(5), 900-911. [More Information]
  • Timmins, H., Saw, W., Cheah, B., Lin, C., Vucic, S., Ahmed, R., Kiernan, M., Park, S. (2017). Cardiometabolic health and risk of amyotrophic lateral sclerosis. Muscle and Nerve, 56(4), 721-725. [More Information]
  • Pickering, H., Murray, J., Lin, C., Cormack, C., Martin, A., Kiernan, M., Krishnan, A. (2017). Fampridine treatment and walking distance in multiple sclerosis: A randomised controlled trial. Clinical Neurophysiology, 128(1), 93-99. [More Information]
  • Moalem-Taylor, G., Baharuddin, B., Bennett, B., Krishnan, A., Huynh, W., Kiernan, M., Lin, C., Shulruf, B., Keoshkerian, E., Cameron, B., et al (2017). Immune dysregulation in patients with carpal tunnel syndrome. Scientific Reports, 7(8218), 1-15. [More Information]
  • Sung, J., Tani, J., Chang, T., Lin, C. (2017). Uncovering sensory axonal dysfunction in asymptomatic type 2 diabetic neuropathy. PloS One, 12(2), 1-15. [More Information]
  • Huynh, W., Pickering, H., Howells, J., Murray, J., Cormack, C., Lin, C., Vucic, S., Kiernan, M., Krishnan, A. (2016). Effect of fampridine on axonal excitability in multiple sclerosis. Clinical Neurophysiology, 127(7), 2636-2642. [More Information]
  • Huynh, W., Vucic, S., Krishnan, A., Lin, C., Kiernan, M. (2016). Exploring the evolution of cortical excitability following acute stroke. Neurorehabilitation and Neural Repair, 30(3), 244-257. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Howells, J., Kiernan, M., Lin, C., Krishnan, A. (2016). In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes. Clinical Neurophysiology, 127(2), 1700-1706. [More Information]
  • Lin, C., Huynh, W. (2016). Is Google good enough for medicine? Journal of Neurology, Neurosurgery and Psychiatry, 87(9), 915-915. [More Information]
  • Mathey, E., Park, S., Hughes, R., Pollard, J., Armati, P., Barnett, M., Taylor, B., Dyck, J., Kiernan, M., Lin, C. (2015). Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype. Journal of Neurology, Neurosurgery and Psychiatry, 86(9), 973-985. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Lin, C., Kiernan, M., Krishnan, A. (2015). Continuous subcutaneous insulin infusion preserves axonal function in Type 1 diabetes mellitus. Diabetes/Metabolism Research and Reviews, 31(2), 175-182. [More Information]
  • Simon, N., Lee, M., Bae, J., Mioshi, E., Lin, C., Pfluger, C., Henderson, R., Vucic, S., Swash, M., Burke, D., Kiernan, M. (2015). Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis. Journal of Neurology, 262(6), 1424-1432. [More Information]
  • Park, S., Vucic, S., Cheah, B., Lin, C., Kirby, A., Robledo, K., Zoing, M., Winhammar, J., Kiernan, M. (2015). Flecainide in Amyotrophic Lateral Sclerosis as a Neuroprotective Strategy (FANS): A Randomized Placebo-Controlled Trial. EBioMedicine, 2(12), 1916-1922. [More Information]
  • Park, S., Sung, J., Tani, J., Kiernan, M., Lin, C. (2015). Reply: biomarkers of 'acute-onset' chronic inflammatory demyelinating polyneuropathy. Brain, 138, 1-2. [More Information]
  • Simon, N., Lin, C., Lee, M., Howells, J., Vucic, S., Burke, D., Kiernan, M. (2015). Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis. Clinical Neurophysiology, 126(4), 828-836. [More Information]
  • Sung, J., Tani, J., Hung, K., Lui, T., Lin, C. (2015). Sensory axonal dysfunction in cervical radiculopathy. Journal of Neurology, Neurosurgery and Psychiatry, 86(6), 640-645. [More Information]
  • Lee, M., Kiernan, M., Macefield, V., Lee, B., Lin, C. (2015). Short-term peripheral nerve stimulation ameliorates axonal dysfunction after spinal cord injury. Journal of Neurophysiology, 113, 3209-3218. [More Information]
  • Park, S., Lin, C., Krishnan, A., Simon, N., Bostock, H., Vincent, A., Kiernan, M. (2014). Axonal dysfunction with voltage gated potassium channel complex antibodies. Experimental Neurology, 261, 337-342. [More Information]
  • Sung, J., Tani, J., Park, S., Kiernan, M., Lin, C. (2014). Early identification of 'acute-onset' chronic inflammatory demyelinating polyneuropathy. Brain, 137(8), 2155-2163. [More Information]
  • Arnold, R., Pussell, B., Howells, J., Grinius, V., Kiernan, M., Lin, C., Krishnan, A. (2014). Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease. Clinical Neurophysiology, 125(1), 179-185. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Lin, C., Kiernan, M., Krishnan, A. (2014). Insulin pump therapy in type 1 diabetes: Potential to be neuroprotective. Clinical Neurophysiology, 125(4), e1-e2. [More Information]
  • Lin, C. (2014). Multifocal motor neuropathy: lost in conduction block? Journal of Neurology, Neurosurgery and Psychiatry, 85(10), 1062-1062. [More Information]
  • Park, S., Kwok, J., Loy, C., Friedlander, M., Lin, C., Krishnan, A., Lewis, C., Kiernan, M. (2014). Paclitaxel-induced neuropathy: potential association of MAPT and GSK3B genotypes. BMC Cancer, 14, 1-5. [More Information]
  • Huynh, W., Lin, C., Krishnan, A., Vucic, S., Kiernan, M. (2014). Transynaptic changes evident in peripheral axonal function after acute cerebellar infarct. Cerebellum, 13(6), 669-676. [More Information]
  • Arnold, R., Pussell, B., Pianta, T., Lin, C., Kiernan, M., Krishnan, A. (2013). Association between calcineurin inhibitor treatment and peripheral nerve dysfunction in renal transplant recipients. American Journal Of Transplantation, 13(9), 2426-2432. [More Information]
  • Arnold, R., Kwai, N., Lin, C., Poynten, A., Kiernan, M., Krishnan, A. (2013). Axonal dysfunction prior to neuropathy onset in type 1 diabetes. Diabetes/Metabolism Research and Reviews, 29(1), 53-59. [More Information]
  • Huynh, W., Krishnan, A., Lin, C., Vucic, S., Katrak, P., Hornberger, M., Kiernan, M. (2013). Botulinum Toxin Modulates Cortical Maladaptation In Post-Stroke Spasticity. Muscle and Nerve, 48(1), 93-99. [More Information]
  • Park, S., Goldstein, D., Krishnan, A., Lin, C., Friedlander, M., Cassidy, J., Koltzenburg, M., Kiernan, M. (2013). Chemotherapy-induced peripheral neurotoxicity: A critical analysis. CA A Cancer Journal for Clinicians, 63(6), 419-437. [More Information]
  • Turner, M., Hardiman, O., Benatar, M., Brooks, B., Chio, A., de Carvalho, M., Ince, P., Lin, C., Miller, R., Mitsumoto, H., Nicholson, G., Vucic, S., et al (2013). Controversies and priorities in amyotrophic lateral sclerosis. The Lancet Neurology, 12(3), 310-322. [More Information]
  • Kwai, N., Arnold, R., Wickremaarachchi, C., Lin, C., Poynten, A., Kiernan, M., Krishnan, A. (2013). Effects of Axonal Ion Channel Dysfunction on Quality of Life in Type 2 Diabetes. Diabetes Care, 36(5), 1272-1277. [More Information]
  • Arnold, R., Pussell, B., Pianta, T., Grinius, V., Lin, C., Kiernan, M., Howells, J., Jardine, M., Krishnan, A. (2013). Effects of hemodiafiltration and high flux hemodialysis on nerve excitability in end-stage kidney disease. PloS One, 8(3), 1-8. [More Information]
  • Farrar, M., Park, S., Lin, C., Kiernan, M. (2013). Evolution of peripheral nerve function in humans: novel insights from motor nerve excitability. Journal of Physiology, 591(1), 273-286. [More Information]
  • Huynh, W., Vucic, S., Krishnan, A., Lin, C., Hornberger, M., Kiernan, M. (2013). Longitudinal Plasticity Across the Neural Axis in Acute Stroke. Neurorehabilitation and Neural Repair, 27(3), 219-229. [More Information]
  • Huynh, W., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2013). Motor Cortex Excitability in Acute Cerebellar Infarct. Cerebellum, 12(6), 826-834. [More Information]
  • Lin, C., Park, S., Krishnan, A. (2013). Porphyric neuropathy. Handbook of Clinical Neurology, 115, 613-627. [More Information]
  • Berger, M., McCallus, D., Lin, C. (2013). Rapid and reversible responses to IVIG in autoimmune neuromuscular diseases suggest mechanisms of action involving competition with functionally important autoantibodies. Journal of the Peripheral Nervous System, 18(4), 275-296. [More Information]
  • Vucic, S., Lin, C., Cheah, B., Murray, J., Menon, P., Krishnan, A., Kiernan, M. (2013). Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis. Brain, 136(5), 1361-1370. [More Information]
  • Fujimaki, Y., Kanai, K., Misawa, S., Shibuya, K., Isose, S., Nasu, S., Sekiguchi, Y., Ohmori, S., Noto, Y., Kugio, Y., et al (2012). Differences in excitability between median and superficial radial sensory axons. Clinical Neurophysiology, 123(7), 1440-1445. [More Information]
  • Bennett, B., Park, S., Lin, C., Friedlander, M., Kiernan, M., Goldstein, D. (2012). Impact of oxaliplatin-induced neuropathy: a patient perspective. Supportive Care in Cancer, 20(11), 2959-2967. [More Information]
  • Krishnan, A., Park, S., Huynh, W., Lin, C., Henderson, R., Kiernan, M. (2012). Impaired energy-dependent processes underlie acute lead neuropathy. Muscle and Nerve, 46(6), 954-956. [More Information]
  • Park, S., Lin, C., Kiernan, M., Koltzenburg, M. (2012). Longitudinal assessment of oxaliplatin-induced neuropathy. Neurology, 78(2), 152. [More Information]
  • Park, S., Lin, C., Kiernan, M. (2012). Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity. Journal of Visualized Experiments, 62, 3439. [More Information]
  • Cheah, B., Lin, C., Park, S., Vucic, S., Krishnan, A., Kiernan, M. (2012). Progressive axonal dysfunction and clinical impairment in amyotrophic lateral sclerosis. Clinical Neurophysiology, 123(12), 2460-2467. [More Information]
  • Sung, J., Park, S., Liu, Y., Kwai, N., Arnold, R., Krishnan, A., Lin, C. (2012). Progressive axonal dysfunction precedes development of neuropathy in type 2 diabetes. Diabetes, 61(6), 1592-1598. [More Information]
  • Pickering, H., Lee, M., Moseley, G., Minei, P., Lin, C. (2012). Sensory disturbances evoked by immobilization of an experimentally inflamed limb. Clinical Neurophysiology, 123(7), e71-e72. [More Information]
  • Park, S., Lin, C., Burke, D., Kiernan, M. (2011). Activity-dependent conduction failure: molecular insights. Journal of the Peripheral Nervous System, 16(3), 159-168. [More Information]
  • Boland, R., Lin, C., Engel, S., Kiernan, M. (2011). Adaptation of motor function after spinal cord injury: novel insights into spinal shock. Brain, 134(2), 495-505. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Dose effects of oxaliplatin on persistent and transient na conductances and the development of neurotoxicity. PloS One, 6(4), e18469-e18469. [More Information]
  • Farrar, M., Vucic, S., Lin, C., Park, S., Johnston, H., du Sart, D., Bostock, H., Kiernan, M. (2011). Dysfunction of axonal membrane conductances in adolescents and young adults with spinal muscular atrophy. Brain, 134(11), 3185-3197. [More Information]
  • Park, S., Lin, C., Krishnan, A., Friedlander, M., Lewis, C., Kiernan, M. (2011). Early, progressive, and sustained dysfunction of sensory axons underlies paclitaxel-induced neuropathy. Muscle and Nerve, 43(3), 367-374. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Long-Term Neuropathy After Oxaliplatin Treatment: Challenging the Dictum of Reversibility. The Oncologist, 16(5), 708-716. [More Information]
  • Lin, C., Krishnan, A., Park, S., Kiernan, M. (2011). Modulatory effects on axonal function after intravenous immunoglobulin therapy in chronic inflammatory demyelinating polyneuropathy. JAMA Neurology, 68(7), 862-869. [More Information]
  • Han, S., Lin, C., Boland, R., Kiernan, M. (2011). Nerve compression, membrane excitability, and symptoms of carpal tunnel syndrome. Muscle and Nerve, 44(3), 402-409. [More Information]
  • Park, S., Goldstein, D., Lin, C., Krishnan, A., Friedlander, M., Kiernan, M. (2011). Neuroprotection for Oxaliplatin-Induced Neurotoxicity: What Happened to Objective Assessment? Journal of Clinical Oncology, 29(18), e553-e554. [More Information]
  • Lin, C., Lee, M., Park, S., Kiernan, M. (2011). Purple pigments: The pathophysiology of acute porphyric neuropathy. Clinical Neurophysiology, 122(12), 2336-2344. [More Information]
  • Krishnan, A., Park, S., Payne, M., Lin, C., Vucic, S., Kiernan, M. (2011). Regional differences in ulnar nerve excitability may predispose to the development of entrapment neuropathy. Clinical Neurophysiology, 122(1), 194-198. [More Information]
  • Park, S., Lin, C., Krishnan, A., Kiernan, M. (2011). The contribution of SK3 polymorphisms to acute oxaliplatin-induced neurotoxicity: direct or indirect effects? Cancer Chemotherapy and Pharmacology, 67(5), 1189-1190. [More Information]
  • Huynh, W., Krishnan, A., Lin, C., Vucic, S., Kiernan, M. (2011). The effects of large artery ischemia and subsequent recanalization on nerve excitability. Muscle and Nerve, 44(5), 841. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Utilising natural activity to dissect the Pathophysiology of acute oxaliplatin-induced neuropathy. Experimental Neurology, 227(1), 120-127. [More Information]
  • Farrar, M., Lin, C., Krishnan, A., Park, S., Andrews, P., Kiernan, M. (2010). Acute, Reversible Axonal Energy Failure During Stroke-Like Episodes in MELAS. Pediatrics, 126(3), e734-e739. [More Information]
  • Han, S., Lin, C., Borland, R., Bilston, L., Kiernan, M. (2010). Changes in human sensory axonal excitability induced by focal nerve compression. Journal of Physiology, 588(10), 1737-1745. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2010). Oxaliplatin-Induced Lhermitte's Phenomenon as a Manifestation of Severe Generalized Neurotoxicity. Oncology, 77(6), 342-348. [More Information]
  • Park, S., Goldstein, D., Lin, C., Krishnan, A., Friedlander, M., Kiernan, M. (2009). Acute abnormalities of sensory nerve function associated with oxaliplatin-induced neurotoxicity. Journal of Clinical Oncology, 27(8), 1243-1249. [More Information]
  • Krishnan, A., Lin, C., Park, S., Kiernan, M. (2009). Axonal ion channels from bench to bedside: a translational neuroscience perspective. Progress in Neurobiology, 89(3), 288-313. [More Information]
  • Krishnan, A., Lin, C., Reddel, S., McGrath, R., Kiernan, M. (2009). Conduction block and impaired axonal function in tick paralysis. Muscle and Nerve, 40(3), 358-362. [More Information]
  • Han, S., Boland, R., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2009). Ischaemic sensitivity of axons in carpal tunnel syndrome. Journal of the Peripheral Nervous System, 14(3), 190-200. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2009). Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy. Brain, 132(10), 2712-2723. [More Information]
  • Krishnan, A., Lin, C., Kiernan, M. (2008). Activity-dependent excitability changes suggest Na+/K+ pump dysfunction in diabetic neuropathy. Brain, 131(Pt 5), 1209-1216. [More Information]
  • Krishnan, A., Lin, C., Park, S., Kiernan, M. (2008). Assessment of nerve excitability in toxic and metabolic neuropathies. Journal of the Peripheral Nervous System, 13(1), 7-26. [More Information]
  • Han, S., Boland, R., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2008). Changes in human sensory axonal excitability induced by an ischaemic insult. Clinical Neurophysiology, 119(9), 2054-2063. [More Information]
  • Park, S., Krishnan, A., Lin, C., Goldstein, D., Friedlander, M., Kiernan, M. (2008). Mechanisms underlying chemotherapy-induced neurotoxicity and the potential for neuroprotective strategies. Current Medicinal Chemistry, 15(29), 3081-3094. [More Information]
  • Lin, C., Krishnan, A., Lee, M., Zagami, A., You, H., Yang, C., Bostock, H., Kiernan, M. (2008). Nerve function and dysfunction in acute intermittent porphyria. Brain, 131(9), 2510-2519. [More Information]
  • Lin, C., Macefield, V., Wallin, G., Elam, M., Engel, S., Kiernan, M. (2007). Axonal changes in spinal cord injured patients distal to the site of injury. Brain, 130(Pt 4), 985-994. [More Information]
  • Ng, K., Lin, C., Murray, N., Burroughs, A., Bostock, H. (2007). Conduction and excitability properties of peripheral nerves in end-stage liver disease. Muscle and Nerve, 35(6), 730-738. [More Information]
  • Z’Graggen, W., Lin, C., Howard, R., Beale, R., Bostock, H. (2006). Nerve excitability changes in critical illness polyneuropathy. Brain, 129(9), 2461-2470. [More Information]
  • Kiernan, M., Isbister, G., Lin, C., Burke, D., Bostock, H. (2005). Acute tetrodotoxin-induced neurotoxicity after ingestion of puffer fish. Annals of Neurology, 57(3), 339-48. [More Information]
  • Bostock, H., Lin, C., Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2005). After-effects of near-threshold stimulation in single human motor axons. Journal of Physiology, 564(3), 931-940. [More Information]
  • Kiernan, M., Krishnan, A., Lin, C., Burke, D., Berkovic, S. (2005). Mutation in the Na+ channel subunit SCN1B produces paradoxical changes in peripheral nerve excitability. Brain, 128(8), 1841-1846. [More Information]
  • Kiernan, M., Lin, C., Burke, D. (2004). Differences In Activity-Dependent Hyperpolarization In Human Sensory And Motor Axons. Journal of Physiology, 558(1), 341-349. [More Information]
  • Cappelen-Smith, C., Lin, C., Burke, D. (2003). Activity-dependent hyperpolarization and impulse conduction in motor axons in patients with carpal tunnel syndrome. Brain, 126(4), 1001-1008. [More Information]
  • Espiritu, M., Lin, C., Burke, D. (2003). Motoneuron excitability and the F wave. Muscle and Nerve, 27(6), 720-727. [More Information]
  • Cappelen-Smith, C., Lin, C., Kuwabara, S., Burke, D. (2002). Conduction block during and after ischaemia in chronic inflammatory demyelinating polyneuropathy. Brain, 125(8), 1850-1858. [More Information]
  • Kuwabara, S., Ogawara, K., Sung, J., Mori, M., Kanai, K., Hattori, T., Yuki, N., Lin, C., Burke, D., Bostock, H. (2002). Differences in membrane properties of axonal and demyelinating Guillain-Barr� syndromes. Annals of Neurology, 52(2), 180-187. [More Information]
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Burke, D. (2002). Effects of voluntary activity on the excitability of motor axons in the peroneal nerve. Muscle and Nerve, 25(2), 176-184. [More Information]
  • Lin, C., Kuwabara, S., Cappelen-Smith, C., Burke, D. (2002). Responses of human sensory and motor axons to the release of ischaemia and to hyperpolarizing currents. Journal of Physiology, 541(3), 1025-1039. [More Information]
  • Lin, C., Grosskreutz, J., Burke, D. (2002). Sodium channel function and the excitability of human cutaneous afferents during ischaemia. Journal of Physiology, 538(2), 435-446. [More Information]
  • Kiernan, M., Lin, C., Andersen, K., Murray, N., Bostock, H. (2001). Clinical evaluation of excitability measures in sensory nerve. Muscle and Nerve, 24(7), 883-892. [More Information]
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Burke, D. (2001). Differences in accommodative properties of median and peroneal motor axons. Journal of Neurology, Neurosurgery and Psychiatry, 70, 372-376. [More Information]
  • Lin, C., Mogyoros, I., Kuwabara, S., Cappelen-Smith, C., Burke, D. (2001). Differences in responses of cutaneous afferents in the human median and sural nerves to ischemia. Muscle and Nerve, 24(11), 1503-1509.
  • Cappelen-Smith, C., Kuwabara, S., Lin, C., Mogyoros, I., Burke, D. (2001). Membrane properties in chronic inflammatory demyelinating polyneuropathy. Brain, 124(12), 2439-2447.
  • Kuwabara, S., Lin, C., Mogyoros, I., Cappelen-Smith, C., Burke, D. (2001). Voluntary contraction impairs the refractory period of transmission in healthy human axons. Journal of Physiology, 531, 265-275. [More Information]
  • Cappelen-Smith, C., Kuwabara, S., Lin, C., Mogyoros, I., Burke, D. (2000). Activity-dependent hyperpolarization and conduction block in chronic inflammatory demyelinating polyneuropathy. Annals of Neurology, 48(6), 826-832.
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Bostock, H., Burke, D. (2000). Excitability properties of median and peroneal motor axons. Muscle and Nerve, 23(9), 1365-1373.

Conferences

  • Han, S., Lin, C., Boland, R., Kiernan, M. (2011). Effects of focal nerve compression on membrane excitability and symptoms in carpal tunnel syndrome. APA Physiotherapy Conference 2011, NA.
  • Boland, R., Lin, C., Krishnan, A., Engel, S., Kiernan, M. (2007). Nerve Excitability Changes In Peripheral Motor Axons In Patients With Acute Spinal Injury. International Brain Research Organisation World Congress of Neuroscience.

2018

  • Kandula, T., Farrar, M., Krishnan, A., Murray, J., Timmins, H., Goldstein, D., Lin, C., Kiernan, M., Park, S. (2018). Multimodal quantitative examination of nerve function in colorectal cancer patients prior to chemotherapy. Muscle and Nerve, 57(4), 615-621. [More Information]

2017

  • Mathey, E., Garg, N., Park, S., Nguyen, T., Baker, S., Yuki, N., Yiannikas, K., Lin, C., Spies, J., Ghaoui, R., Barnett, M., Vucic, S., Pollard, J., Kiernan, M. (2017). Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies. Journal of Neuroimmunology, 309, 41-46. [More Information]
  • Farrar, M., Lee, M., Howells, J., Andrews, P., Lin, C. (2017). Burning pain: axonal dysfunction in erythromelalgia. Pain, 158(5), 900-911. [More Information]
  • Timmins, H., Saw, W., Cheah, B., Lin, C., Vucic, S., Ahmed, R., Kiernan, M., Park, S. (2017). Cardiometabolic health and risk of amyotrophic lateral sclerosis. Muscle and Nerve, 56(4), 721-725. [More Information]
  • Pickering, H., Murray, J., Lin, C., Cormack, C., Martin, A., Kiernan, M., Krishnan, A. (2017). Fampridine treatment and walking distance in multiple sclerosis: A randomised controlled trial. Clinical Neurophysiology, 128(1), 93-99. [More Information]
  • Moalem-Taylor, G., Baharuddin, B., Bennett, B., Krishnan, A., Huynh, W., Kiernan, M., Lin, C., Shulruf, B., Keoshkerian, E., Cameron, B., et al (2017). Immune dysregulation in patients with carpal tunnel syndrome. Scientific Reports, 7(8218), 1-15. [More Information]
  • Sung, J., Tani, J., Chang, T., Lin, C. (2017). Uncovering sensory axonal dysfunction in asymptomatic type 2 diabetic neuropathy. PloS One, 12(2), 1-15. [More Information]

2016

  • Park, S., Lin, C., Kiernan, M. (2016). Axonal excitability: molecular basis and assessment in the clinic. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 97-105). Oxford: Oxford University Press.
  • Huynh, W., Pickering, H., Howells, J., Murray, J., Cormack, C., Lin, C., Vucic, S., Kiernan, M., Krishnan, A. (2016). Effect of fampridine on axonal excitability in multiple sclerosis. Clinical Neurophysiology, 127(7), 2636-2642. [More Information]
  • Huynh, W., Vucic, S., Krishnan, A., Lin, C., Kiernan, M. (2016). Exploring the evolution of cortical excitability following acute stroke. Neurorehabilitation and Neural Repair, 30(3), 244-257. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Howells, J., Kiernan, M., Lin, C., Krishnan, A. (2016). In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes. Clinical Neurophysiology, 127(2), 1700-1706. [More Information]
  • Lin, C., Huynh, W. (2016). Is Google good enough for medicine? Journal of Neurology, Neurosurgery and Psychiatry, 87(9), 915-915. [More Information]

2015

  • Mathey, E., Park, S., Hughes, R., Pollard, J., Armati, P., Barnett, M., Taylor, B., Dyck, J., Kiernan, M., Lin, C. (2015). Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype. Journal of Neurology, Neurosurgery and Psychiatry, 86(9), 973-985. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Lin, C., Kiernan, M., Krishnan, A. (2015). Continuous subcutaneous insulin infusion preserves axonal function in Type 1 diabetes mellitus. Diabetes/Metabolism Research and Reviews, 31(2), 175-182. [More Information]
  • Simon, N., Lee, M., Bae, J., Mioshi, E., Lin, C., Pfluger, C., Henderson, R., Vucic, S., Swash, M., Burke, D., Kiernan, M. (2015). Dissociated lower limb muscle involvement in amyotrophic lateral sclerosis. Journal of Neurology, 262(6), 1424-1432. [More Information]
  • Park, S., Vucic, S., Cheah, B., Lin, C., Kirby, A., Robledo, K., Zoing, M., Winhammar, J., Kiernan, M. (2015). Flecainide in Amyotrophic Lateral Sclerosis as a Neuroprotective Strategy (FANS): A Randomized Placebo-Controlled Trial. EBioMedicine, 2(12), 1916-1922. [More Information]
  • Park, S., Sung, J., Tani, J., Kiernan, M., Lin, C. (2015). Reply: biomarkers of 'acute-onset' chronic inflammatory demyelinating polyneuropathy. Brain, 138, 1-2. [More Information]
  • Simon, N., Lin, C., Lee, M., Howells, J., Vucic, S., Burke, D., Kiernan, M. (2015). Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis. Clinical Neurophysiology, 126(4), 828-836. [More Information]
  • Sung, J., Tani, J., Hung, K., Lui, T., Lin, C. (2015). Sensory axonal dysfunction in cervical radiculopathy. Journal of Neurology, Neurosurgery and Psychiatry, 86(6), 640-645. [More Information]
  • Lee, M., Kiernan, M., Macefield, V., Lee, B., Lin, C. (2015). Short-term peripheral nerve stimulation ameliorates axonal dysfunction after spinal cord injury. Journal of Neurophysiology, 113, 3209-3218. [More Information]

2014

  • Park, S., Lin, C., Krishnan, A., Simon, N., Bostock, H., Vincent, A., Kiernan, M. (2014). Axonal dysfunction with voltage gated potassium channel complex antibodies. Experimental Neurology, 261, 337-342. [More Information]
  • Sung, J., Tani, J., Park, S., Kiernan, M., Lin, C. (2014). Early identification of 'acute-onset' chronic inflammatory demyelinating polyneuropathy. Brain, 137(8), 2155-2163. [More Information]
  • Arnold, R., Pussell, B., Howells, J., Grinius, V., Kiernan, M., Lin, C., Krishnan, A. (2014). Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease. Clinical Neurophysiology, 125(1), 179-185. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Lin, C., Kiernan, M., Krishnan, A. (2014). Insulin pump therapy in type 1 diabetes: Potential to be neuroprotective. Clinical Neurophysiology, 125(4), e1-e2. [More Information]
  • Lin, C. (2014). Multifocal motor neuropathy: lost in conduction block? Journal of Neurology, Neurosurgery and Psychiatry, 85(10), 1062-1062. [More Information]
  • Park, S., Kwok, J., Loy, C., Friedlander, M., Lin, C., Krishnan, A., Lewis, C., Kiernan, M. (2014). Paclitaxel-induced neuropathy: potential association of MAPT and GSK3B genotypes. BMC Cancer, 14, 1-5. [More Information]
  • Huynh, W., Lin, C., Krishnan, A., Vucic, S., Kiernan, M. (2014). Transynaptic changes evident in peripheral axonal function after acute cerebellar infarct. Cerebellum, 13(6), 669-676. [More Information]

2013

  • Arnold, R., Pussell, B., Pianta, T., Lin, C., Kiernan, M., Krishnan, A. (2013). Association between calcineurin inhibitor treatment and peripheral nerve dysfunction in renal transplant recipients. American Journal Of Transplantation, 13(9), 2426-2432. [More Information]
  • Arnold, R., Kwai, N., Lin, C., Poynten, A., Kiernan, M., Krishnan, A. (2013). Axonal dysfunction prior to neuropathy onset in type 1 diabetes. Diabetes/Metabolism Research and Reviews, 29(1), 53-59. [More Information]
  • Huynh, W., Krishnan, A., Lin, C., Vucic, S., Katrak, P., Hornberger, M., Kiernan, M. (2013). Botulinum Toxin Modulates Cortical Maladaptation In Post-Stroke Spasticity. Muscle and Nerve, 48(1), 93-99. [More Information]
  • Park, S., Goldstein, D., Krishnan, A., Lin, C., Friedlander, M., Cassidy, J., Koltzenburg, M., Kiernan, M. (2013). Chemotherapy-induced peripheral neurotoxicity: A critical analysis. CA A Cancer Journal for Clinicians, 63(6), 419-437. [More Information]
  • Turner, M., Hardiman, O., Benatar, M., Brooks, B., Chio, A., de Carvalho, M., Ince, P., Lin, C., Miller, R., Mitsumoto, H., Nicholson, G., Vucic, S., et al (2013). Controversies and priorities in amyotrophic lateral sclerosis. The Lancet Neurology, 12(3), 310-322. [More Information]
  • Kwai, N., Arnold, R., Wickremaarachchi, C., Lin, C., Poynten, A., Kiernan, M., Krishnan, A. (2013). Effects of Axonal Ion Channel Dysfunction on Quality of Life in Type 2 Diabetes. Diabetes Care, 36(5), 1272-1277. [More Information]
  • Arnold, R., Pussell, B., Pianta, T., Grinius, V., Lin, C., Kiernan, M., Howells, J., Jardine, M., Krishnan, A. (2013). Effects of hemodiafiltration and high flux hemodialysis on nerve excitability in end-stage kidney disease. PloS One, 8(3), 1-8. [More Information]
  • Farrar, M., Park, S., Lin, C., Kiernan, M. (2013). Evolution of peripheral nerve function in humans: novel insights from motor nerve excitability. Journal of Physiology, 591(1), 273-286. [More Information]
  • Huynh, W., Vucic, S., Krishnan, A., Lin, C., Hornberger, M., Kiernan, M. (2013). Longitudinal Plasticity Across the Neural Axis in Acute Stroke. Neurorehabilitation and Neural Repair, 27(3), 219-229. [More Information]
  • Huynh, W., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2013). Motor Cortex Excitability in Acute Cerebellar Infarct. Cerebellum, 12(6), 826-834. [More Information]
  • Lin, C., Park, S., Krishnan, A. (2013). Porphyric neuropathy. Handbook of Clinical Neurology, 115, 613-627. [More Information]
  • Lin, C., Park, S., Krishnan, A. (2013). Porphyric neuropathy. In Gerard Said and Christian Krarup (Eds.), Handbook of Clinical Neurology: Vol 115 Peripheral Nerve Disorders, (pp. 613-627). Amsterdam: Elsevier. [More Information]
  • Berger, M., McCallus, D., Lin, C. (2013). Rapid and reversible responses to IVIG in autoimmune neuromuscular diseases suggest mechanisms of action involving competition with functionally important autoantibodies. Journal of the Peripheral Nervous System, 18(4), 275-296. [More Information]
  • Vucic, S., Lin, C., Cheah, B., Murray, J., Menon, P., Krishnan, A., Kiernan, M. (2013). Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis. Brain, 136(5), 1361-1370. [More Information]

2012

  • Fujimaki, Y., Kanai, K., Misawa, S., Shibuya, K., Isose, S., Nasu, S., Sekiguchi, Y., Ohmori, S., Noto, Y., Kugio, Y., et al (2012). Differences in excitability between median and superficial radial sensory axons. Clinical Neurophysiology, 123(7), 1440-1445. [More Information]
  • Bennett, B., Park, S., Lin, C., Friedlander, M., Kiernan, M., Goldstein, D. (2012). Impact of oxaliplatin-induced neuropathy: a patient perspective. Supportive Care in Cancer, 20(11), 2959-2967. [More Information]
  • Krishnan, A., Park, S., Huynh, W., Lin, C., Henderson, R., Kiernan, M. (2012). Impaired energy-dependent processes underlie acute lead neuropathy. Muscle and Nerve, 46(6), 954-956. [More Information]
  • Park, S., Lin, C., Kiernan, M., Koltzenburg, M. (2012). Longitudinal assessment of oxaliplatin-induced neuropathy. Neurology, 78(2), 152. [More Information]
  • Park, S., Lin, C., Kiernan, M. (2012). Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity. Journal of Visualized Experiments, 62, 3439. [More Information]
  • Kiernan, M., Lin, C. (2012). Nerve excitability: a clinical translation. In Michael J. Aminoff (Eds.), Aminoffs Electrodiagnosis in Clinical Neurology, (pp. 345-365). China: Saunders Elsevier. [More Information]
  • Cheah, B., Lin, C., Park, S., Vucic, S., Krishnan, A., Kiernan, M. (2012). Progressive axonal dysfunction and clinical impairment in amyotrophic lateral sclerosis. Clinical Neurophysiology, 123(12), 2460-2467. [More Information]
  • Sung, J., Park, S., Liu, Y., Kwai, N., Arnold, R., Krishnan, A., Lin, C. (2012). Progressive axonal dysfunction precedes development of neuropathy in type 2 diabetes. Diabetes, 61(6), 1592-1598. [More Information]
  • Pickering, H., Lee, M., Moseley, G., Minei, P., Lin, C. (2012). Sensory disturbances evoked by immobilization of an experimentally inflamed limb. Clinical Neurophysiology, 123(7), e71-e72. [More Information]

2011

  • Park, S., Lin, C., Burke, D., Kiernan, M. (2011). Activity-dependent conduction failure: molecular insights. Journal of the Peripheral Nervous System, 16(3), 159-168. [More Information]
  • Boland, R., Lin, C., Engel, S., Kiernan, M. (2011). Adaptation of motor function after spinal cord injury: novel insights into spinal shock. Brain, 134(2), 495-505. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Dose effects of oxaliplatin on persistent and transient na conductances and the development of neurotoxicity. PloS One, 6(4), e18469-e18469. [More Information]
  • Farrar, M., Vucic, S., Lin, C., Park, S., Johnston, H., du Sart, D., Bostock, H., Kiernan, M. (2011). Dysfunction of axonal membrane conductances in adolescents and young adults with spinal muscular atrophy. Brain, 134(11), 3185-3197. [More Information]
  • Park, S., Lin, C., Krishnan, A., Friedlander, M., Lewis, C., Kiernan, M. (2011). Early, progressive, and sustained dysfunction of sensory axons underlies paclitaxel-induced neuropathy. Muscle and Nerve, 43(3), 367-374. [More Information]
  • Han, S., Lin, C., Boland, R., Kiernan, M. (2011). Effects of focal nerve compression on membrane excitability and symptoms in carpal tunnel syndrome. APA Physiotherapy Conference 2011, NA.
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Long-Term Neuropathy After Oxaliplatin Treatment: Challenging the Dictum of Reversibility. The Oncologist, 16(5), 708-716. [More Information]
  • Lin, C., Krishnan, A., Park, S., Kiernan, M. (2011). Modulatory effects on axonal function after intravenous immunoglobulin therapy in chronic inflammatory demyelinating polyneuropathy. JAMA Neurology, 68(7), 862-869. [More Information]
  • Han, S., Lin, C., Boland, R., Kiernan, M. (2011). Nerve compression, membrane excitability, and symptoms of carpal tunnel syndrome. Muscle and Nerve, 44(3), 402-409. [More Information]
  • Park, S., Goldstein, D., Lin, C., Krishnan, A., Friedlander, M., Kiernan, M. (2011). Neuroprotection for Oxaliplatin-Induced Neurotoxicity: What Happened to Objective Assessment? Journal of Clinical Oncology, 29(18), e553-e554. [More Information]
  • Lin, C., Lee, M., Park, S., Kiernan, M. (2011). Purple pigments: The pathophysiology of acute porphyric neuropathy. Clinical Neurophysiology, 122(12), 2336-2344. [More Information]
  • Krishnan, A., Park, S., Payne, M., Lin, C., Vucic, S., Kiernan, M. (2011). Regional differences in ulnar nerve excitability may predispose to the development of entrapment neuropathy. Clinical Neurophysiology, 122(1), 194-198. [More Information]
  • Park, S., Lin, C., Krishnan, A., Kiernan, M. (2011). The contribution of SK3 polymorphisms to acute oxaliplatin-induced neurotoxicity: direct or indirect effects? Cancer Chemotherapy and Pharmacology, 67(5), 1189-1190. [More Information]
  • Huynh, W., Krishnan, A., Lin, C., Vucic, S., Kiernan, M. (2011). The effects of large artery ischemia and subsequent recanalization on nerve excitability. Muscle and Nerve, 44(5), 841. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2011). Utilising natural activity to dissect the Pathophysiology of acute oxaliplatin-induced neuropathy. Experimental Neurology, 227(1), 120-127. [More Information]

2010

  • Farrar, M., Lin, C., Krishnan, A., Park, S., Andrews, P., Kiernan, M. (2010). Acute, Reversible Axonal Energy Failure During Stroke-Like Episodes in MELAS. Pediatrics, 126(3), e734-e739. [More Information]
  • Han, S., Lin, C., Borland, R., Bilston, L., Kiernan, M. (2010). Changes in human sensory axonal excitability induced by focal nerve compression. Journal of Physiology, 588(10), 1737-1745. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2010). Oxaliplatin-Induced Lhermitte's Phenomenon as a Manifestation of Severe Generalized Neurotoxicity. Oncology, 77(6), 342-348. [More Information]

2009

  • Park, S., Goldstein, D., Lin, C., Krishnan, A., Friedlander, M., Kiernan, M. (2009). Acute abnormalities of sensory nerve function associated with oxaliplatin-induced neurotoxicity. Journal of Clinical Oncology, 27(8), 1243-1249. [More Information]
  • Krishnan, A., Lin, C., Park, S., Kiernan, M. (2009). Axonal ion channels from bench to bedside: a translational neuroscience perspective. Progress in Neurobiology, 89(3), 288-313. [More Information]
  • Krishnan, A., Lin, C., Reddel, S., McGrath, R., Kiernan, M. (2009). Conduction block and impaired axonal function in tick paralysis. Muscle and Nerve, 40(3), 358-362. [More Information]
  • Han, S., Boland, R., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2009). Ischaemic sensitivity of axons in carpal tunnel syndrome. Journal of the Peripheral Nervous System, 14(3), 190-200. [More Information]
  • Park, S., Lin, C., Krishnan, A., Goldstein, D., Friedlander, M., Kiernan, M. (2009). Oxaliplatin-induced neurotoxicity: changes in axonal excitability precede development of neuropathy. Brain, 132(10), 2712-2723. [More Information]

2008

  • Krishnan, A., Lin, C., Kiernan, M. (2008). Activity-dependent excitability changes suggest Na+/K+ pump dysfunction in diabetic neuropathy. Brain, 131(Pt 5), 1209-1216. [More Information]
  • Krishnan, A., Lin, C., Park, S., Kiernan, M. (2008). Assessment of nerve excitability in toxic and metabolic neuropathies. Journal of the Peripheral Nervous System, 13(1), 7-26. [More Information]
  • Han, S., Boland, R., Krishnan, A., Vucic, S., Lin, C., Kiernan, M. (2008). Changes in human sensory axonal excitability induced by an ischaemic insult. Clinical Neurophysiology, 119(9), 2054-2063. [More Information]
  • Park, S., Krishnan, A., Lin, C., Goldstein, D., Friedlander, M., Kiernan, M. (2008). Mechanisms underlying chemotherapy-induced neurotoxicity and the potential for neuroprotective strategies. Current Medicinal Chemistry, 15(29), 3081-3094. [More Information]
  • Lin, C., Krishnan, A., Lee, M., Zagami, A., You, H., Yang, C., Bostock, H., Kiernan, M. (2008). Nerve function and dysfunction in acute intermittent porphyria. Brain, 131(9), 2510-2519. [More Information]

2007

  • Lin, C., Macefield, V., Wallin, G., Elam, M., Engel, S., Kiernan, M. (2007). Axonal changes in spinal cord injured patients distal to the site of injury. Brain, 130(Pt 4), 985-994. [More Information]
  • Ng, K., Lin, C., Murray, N., Burroughs, A., Bostock, H. (2007). Conduction and excitability properties of peripheral nerves in end-stage liver disease. Muscle and Nerve, 35(6), 730-738. [More Information]
  • Boland, R., Lin, C., Krishnan, A., Engel, S., Kiernan, M. (2007). Nerve Excitability Changes In Peripheral Motor Axons In Patients With Acute Spinal Injury. International Brain Research Organisation World Congress of Neuroscience.

2006

  • Z’Graggen, W., Lin, C., Howard, R., Beale, R., Bostock, H. (2006). Nerve excitability changes in critical illness polyneuropathy. Brain, 129(9), 2461-2470. [More Information]

2005

  • Kiernan, M., Isbister, G., Lin, C., Burke, D., Bostock, H. (2005). Acute tetrodotoxin-induced neurotoxicity after ingestion of puffer fish. Annals of Neurology, 57(3), 339-48. [More Information]
  • Bostock, H., Lin, C., Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2005). After-effects of near-threshold stimulation in single human motor axons. Journal of Physiology, 564(3), 931-940. [More Information]
  • Kiernan, M., Krishnan, A., Lin, C., Burke, D., Berkovic, S. (2005). Mutation in the Na+ channel subunit SCN1B produces paradoxical changes in peripheral nerve excitability. Brain, 128(8), 1841-1846. [More Information]

2004

  • Kiernan, M., Lin, C., Burke, D. (2004). Differences In Activity-Dependent Hyperpolarization In Human Sensory And Motor Axons. Journal of Physiology, 558(1), 341-349. [More Information]

2003

  • Cappelen-Smith, C., Lin, C., Burke, D. (2003). Activity-dependent hyperpolarization and impulse conduction in motor axons in patients with carpal tunnel syndrome. Brain, 126(4), 1001-1008. [More Information]
  • Espiritu, M., Lin, C., Burke, D. (2003). Motoneuron excitability and the F wave. Muscle and Nerve, 27(6), 720-727. [More Information]

2002

  • Cappelen-Smith, C., Lin, C., Kuwabara, S., Burke, D. (2002). Conduction block during and after ischaemia in chronic inflammatory demyelinating polyneuropathy. Brain, 125(8), 1850-1858. [More Information]
  • Kuwabara, S., Ogawara, K., Sung, J., Mori, M., Kanai, K., Hattori, T., Yuki, N., Lin, C., Burke, D., Bostock, H. (2002). Differences in membrane properties of axonal and demyelinating Guillain-Barr� syndromes. Annals of Neurology, 52(2), 180-187. [More Information]
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Burke, D. (2002). Effects of voluntary activity on the excitability of motor axons in the peroneal nerve. Muscle and Nerve, 25(2), 176-184. [More Information]
  • Lin, C., Kuwabara, S., Cappelen-Smith, C., Burke, D. (2002). Responses of human sensory and motor axons to the release of ischaemia and to hyperpolarizing currents. Journal of Physiology, 541(3), 1025-1039. [More Information]
  • Lin, C., Grosskreutz, J., Burke, D. (2002). Sodium channel function and the excitability of human cutaneous afferents during ischaemia. Journal of Physiology, 538(2), 435-446. [More Information]

2001

  • Kiernan, M., Lin, C., Andersen, K., Murray, N., Bostock, H. (2001). Clinical evaluation of excitability measures in sensory nerve. Muscle and Nerve, 24(7), 883-892. [More Information]
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Burke, D. (2001). Differences in accommodative properties of median and peroneal motor axons. Journal of Neurology, Neurosurgery and Psychiatry, 70, 372-376. [More Information]
  • Lin, C., Mogyoros, I., Kuwabara, S., Cappelen-Smith, C., Burke, D. (2001). Differences in responses of cutaneous afferents in the human median and sural nerves to ischemia. Muscle and Nerve, 24(11), 1503-1509.
  • Cappelen-Smith, C., Kuwabara, S., Lin, C., Mogyoros, I., Burke, D. (2001). Membrane properties in chronic inflammatory demyelinating polyneuropathy. Brain, 124(12), 2439-2447.
  • Kuwabara, S., Lin, C., Mogyoros, I., Cappelen-Smith, C., Burke, D. (2001). Voluntary contraction impairs the refractory period of transmission in healthy human axons. Journal of Physiology, 531, 265-275. [More Information]

2000

  • Cappelen-Smith, C., Kuwabara, S., Lin, C., Mogyoros, I., Burke, D. (2000). Activity-dependent hyperpolarization and conduction block in chronic inflammatory demyelinating polyneuropathy. Annals of Neurology, 48(6), 826-832.
  • Kuwabara, S., Cappelen-Smith, C., Lin, C., Mogyoros, I., Bostock, H., Burke, D. (2000). Excitability properties of median and peroneal motor axons. Muscle and Nerve, 23(9), 1365-1373.
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