Dr Coral Chamberlain

Honorary Senior Research Fellow
Anatomy & Histology, School of Medical Sciences
Bosch Institute

Telephone +61 2 9036 5458
Fax +61 2 9351 2813

Map

Selected grants

2005

  • New strategies for preventing cataract and PCO (after cataract); Chamberlain C, Calford M; Rebecca L Cooper Medical Research Foundation/Rebecca Cooper Medical Research Foundation.

2001

  • Strategies for preventing or treating cataract research agreement between TA Med Pty Ltd and the University of Sydney; Eutick M, Chamberlain C; TA Med Pty Ltd/BLO Project.

2000

  • Capsule production in lens explants: Role of TGF-BETA and FGF (1994); McAvoy J, Chamberlain C; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Studies relating to cataract pervention; Chamberlain C, Perera A, Naughton C, Thiebaud D, Hopper K, LaPointe L, Daniels R, Sharp S; Enterix Pty Ltd/Research Support.
  • Induction of cataract by TGF-Beta: effect of other growth factors and the ocular media; Chamberlain C, McAvoy J; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Chamberlain, C., Mansfield, K., Cerra, A. (2009). Glutathione and catalase suppress TGFß-induced cataract-related changes in cultured rat lenses and lens epithelial explants. Molecular Vision, 15, 895-905. [More Information]
  • Mansour, H., Chamberlain, C., Weible, M., Hughes, S., Chu, Y., Chan-Ling, T. (2008). Aging-related changes in astrocytes in the rat retina: Imbalance between cell proliferation and cell death reduces astrocyte availability. Aging Cell, 7(4), 526-540. [More Information]
  • Chamberlain, C., Chan-Ling, T., Huang, W., Sarafian, R. (2008). MHC class II expression by beta2 integrin (CD18)-positive microglia, macrophages and macrophage-like cells in rabbit retina. Neuron Glia Biology, 4(4), 285-294. [More Information]
  • Chamberlain, C., Mansfield, K., Cerra, A. (2008). Nitric oxide, a survival factor for lens epithelial cells. Molecular Vision, 14, 983-991. [More Information]
  • Symonds, J., Lovicu, F., Chamberlain, C. (2006). Differing effects of dexamethasone and diclofenac on posterior capsule opacification-like changes in a rat lens explant model. Experimental Eye Research, 83(4), 771-782. [More Information]
  • Symonds, J., Lovicu, F., Chamberlain, C. (2006). Posterior capsule opacification-like changes in rat lens explants cultured with TGFbeta and FGF: effects of cell coverage and regional differences. Experimental Eye Research, 82(4), 693-699. [More Information]
  • Wederell, E., Brown, H., O'Connor, M., Chamberlain, C., McAvoy, J., de Iongh, R. (2005). Laminin-binding integrins in rat lens morphogenesis and their regulation during fibre differentiation. Experimental Eye Research, 81(3), 326-39. [More Information]
  • Mansfield, K., Cerra, A., Chamberlain, C. (2004). Effects Of Dexamethasone On Posterior Capsule Opacification-Like Changes In A Rat Lens Explant Model. Molecular Vision, 10(1), 728-737.
  • Mansfield, K., Cerra, A., Chamberlain, C. (2004). Fgf-2 Counteracts Loss Of Tgfbeta Affected Cells From Rat Lens Explants: Implications For Pco (After Cataract). Molecular Vision, 10(1), 521-532.
  • Cerra, A., Mansfield, K., Chamberlain, C. (2003). Exacerbation of TGF-beta-induced cataract by FGF-2 in cultured rat lenses. Molecular Vision, 9, 689-700.
  • Maruno, K., Lovicu, F., Chamberlain, C., McAvoy, J. (2002). Apoptosis is a feature of TGFb-induced cataract. Clinical and Experimental Optometry, 85(2), 76-82.
  • Kok, A., Lovicu, F., Chamberlain, C., McAvoy, J. (2002). Influence of platelet-derived growth factor on lens epithelial cell proliferation and differentiation. Growth Factors, , 27-34.
  • Lovicu, F., Schulz, M., Hales, A., Vincent, L., Overbeek, P., Chamberlain, C., McAvoy, J. (2002). TGFB induces morphological and molecular changes similar to human anterior subcapsular cataract. The British Journal of Ophthalmology, 86(2), 220-226.
  • De Iongh, R., Chamberlain, C., Hales, A., McAvoy, J., Gordon-Thomson, C. (2001). TGFB receptor expression in lens: Implications for differentiation and cataractogenesis. Experimental Eye Research, 72 (5), 649-659.

Patents

  • McAvoy, J., Chamberlain, C. (2006). A Method For Preventing Or Controlling Cataract. Patent No. 735895. Austria, Belgium, Denmark, France, Germany, Greece, Ireland, Italy, Liechtenstein, Luxembourg, Monaco, Netherlands, Portugal, Spain, Sweden, Switzerland, United Kingdom.

2009

  • Chamberlain, C., Mansfield, K., Cerra, A. (2009). Glutathione and catalase suppress TGFß-induced cataract-related changes in cultured rat lenses and lens epithelial explants. Molecular Vision, 15, 895-905. [More Information]

2008

  • Mansour, H., Chamberlain, C., Weible, M., Hughes, S., Chu, Y., Chan-Ling, T. (2008). Aging-related changes in astrocytes in the rat retina: Imbalance between cell proliferation and cell death reduces astrocyte availability. Aging Cell, 7(4), 526-540. [More Information]
  • Chamberlain, C., Chan-Ling, T., Huang, W., Sarafian, R. (2008). MHC class II expression by beta2 integrin (CD18)-positive microglia, macrophages and macrophage-like cells in rabbit retina. Neuron Glia Biology, 4(4), 285-294. [More Information]
  • Chamberlain, C., Mansfield, K., Cerra, A. (2008). Nitric oxide, a survival factor for lens epithelial cells. Molecular Vision, 14, 983-991. [More Information]

2006

  • McAvoy, J., Chamberlain, C. (2006). A Method For Preventing Or Controlling Cataract. Patent No. 735895. Austria, Belgium, Denmark, France, Germany, Greece, Ireland, Italy, Liechtenstein, Luxembourg, Monaco, Netherlands, Portugal, Spain, Sweden, Switzerland, United Kingdom.
  • Symonds, J., Lovicu, F., Chamberlain, C. (2006). Differing effects of dexamethasone and diclofenac on posterior capsule opacification-like changes in a rat lens explant model. Experimental Eye Research, 83(4), 771-782. [More Information]
  • Symonds, J., Lovicu, F., Chamberlain, C. (2006). Posterior capsule opacification-like changes in rat lens explants cultured with TGFbeta and FGF: effects of cell coverage and regional differences. Experimental Eye Research, 82(4), 693-699. [More Information]

2005

  • Wederell, E., Brown, H., O'Connor, M., Chamberlain, C., McAvoy, J., de Iongh, R. (2005). Laminin-binding integrins in rat lens morphogenesis and their regulation during fibre differentiation. Experimental Eye Research, 81(3), 326-39. [More Information]

2004

  • Mansfield, K., Cerra, A., Chamberlain, C. (2004). Effects Of Dexamethasone On Posterior Capsule Opacification-Like Changes In A Rat Lens Explant Model. Molecular Vision, 10(1), 728-737.
  • Mansfield, K., Cerra, A., Chamberlain, C. (2004). Fgf-2 Counteracts Loss Of Tgfbeta Affected Cells From Rat Lens Explants: Implications For Pco (After Cataract). Molecular Vision, 10(1), 521-532.

2003

  • Cerra, A., Mansfield, K., Chamberlain, C. (2003). Exacerbation of TGF-beta-induced cataract by FGF-2 in cultured rat lenses. Molecular Vision, 9, 689-700.

2002

  • Maruno, K., Lovicu, F., Chamberlain, C., McAvoy, J. (2002). Apoptosis is a feature of TGFb-induced cataract. Clinical and Experimental Optometry, 85(2), 76-82.
  • Kok, A., Lovicu, F., Chamberlain, C., McAvoy, J. (2002). Influence of platelet-derived growth factor on lens epithelial cell proliferation and differentiation. Growth Factors, , 27-34.
  • Lovicu, F., Schulz, M., Hales, A., Vincent, L., Overbeek, P., Chamberlain, C., McAvoy, J. (2002). TGFB induces morphological and molecular changes similar to human anterior subcapsular cataract. The British Journal of Ophthalmology, 86(2), 220-226.

2001

  • De Iongh, R., Chamberlain, C., Hales, A., McAvoy, J., Gordon-Thomson, C. (2001). TGFB receptor expression in lens: Implications for differentiation and cataractogenesis. Experimental Eye Research, 72 (5), 649-659.

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