China	(Professor Xiyun Yan, National Key Laboratory of Biomolecules,Institute of Biophysics, Chinese Academy of Sciences Datun Road No.15, Beijing 100101) Research collaboration involving the use of a monoclonal anti-CD146 antibody to identify the role of CD146 in human heart failure.
France	(Inserm U915, Institut du Thorax, Nantes Faculte de Medecine) Research collaboration between Dr Marja Steenman, my laboratory and a graduate student, Maurizio Stefani.
Germany	(Dr. Wolfgang A. Linke, Department of Cardiovascular Physiology, Institute of Physiology, Faculty of Medicine Ruhr University Bochum. D-44780 Bochum) Collaboration with Dr Wolfgang Linke on the role of protein kinase G in modulating the passive stiffness of phosphorylated titin, a giant protein component of the cardiomyocyte.
Ireland	(Michael J. Dunn, PhD, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4) Research collaboration involving the protective effect of phosphorylated Hsp27 in human coronary arteries through actin stabilisation
Ireland	(University College Dublin) Working with Prof. Michael Dunn
Japan	(Shin''ichi Ishiwata, Ph.D., Professor of Biophysics, Department of Physics, School of Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo, 169-8555) Awarded a JSRS Travel grant to visit in September 2008. In 2009 we commenced a collaborative, working on SPontaneous Oscilatory Contractions (SPOCs) as a method of quantifying functional deficits in end-stage failing human cardiomyocytes.
Netherlands	(D.Dooijes, PhD., Clinical Molecular Geneticist Department of of Clinical Genetics, Erasmus Medical College, Dr. Molewaterplein 50, 3015GE, ROTTERDAM) Collaboration involving the genotyping og familial heart failure in man.
Netherlands	(Institute for Cardiovascular Research. Free University Amsterdam) Collaboration with Jolanda Van Der Velden and others in her laboratory
Sweden	(University of Uppsala, HPR Research Group, Rudbeck Laboratory, Dag Hammarskjold 20 S-751-85, Uppsala) Research collaboration with Prof Fredrik Ponten involving the use of tissue microarrays of failing and non-failing human hearts.
United Kingdom	(Ayesha De Souza, PhD, Department of Cardiac & Vascular Sciences, St. George''s Hospital, University of London, Cranmer Terrace Tooting, London, SW17 0RE) Research collaboration involving proteomic and metabolomic analysis of failing human left atria to reveal the molecular mechanism underlying atrial fibrillation.
United Kingdom	(Dr Michael Gray, Epithelial Research Group, Institute for Cell and Molecular Biosciences, University Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH) Research collaboration involving the role of a protein kinase called sgk1 in human heart failure.
United Kingdom	(Elizabeth Ehler PhD., Kings College London BHF Research Excellence Centre, The Randall Division of Cell and Molecular Biophysics, New Hunts House, Guys Campus, London SE1 1UL) Research collaboration involving measurement of expression levels of a muscle-specific isoform of the formin (FHOD3) in the human heart and its role in myofibril maintenance
United Kingdom	(Imperial College London) Collaborating with Prof Steve Marston on molecular defects in failing human cardiac proteins, particularly the proteins that regulate contraction in the heart.
United Kingdom	(Jonathan C. Kentish, MA, PhD Cardiovascular Division,King''s College London Rayne Institute, St. Thomas''s Hospital, London SE1 7EH) Collaborating involving a study of normal passive viscoelasticity but abnormal myofibrillar contractile function in patients with obstructive hypertrophic cardiomyopathy.
United Kingdom	(Paul Riley PhD, Molecular Medicine Unit, UCL-Institute of Child Health, 30 Guilford Street, London, WC1N 1EH) Research collaboration involving hypertrophic cardiomyopathy (HOCM) myectomy heart samples to study transcriptional/microRNA regulation of sarcomeric gene expression in human heart failure.
United States	(Anne M. Murphy MD, The Johns Hopkins University Medical School, 720 Rutland Avenue Ross Bldg. 1144, Baltimore, MD 21205) Research collaboration involving mutations in cardiac troponin I in failing and non-failing human left ventricles.
United States	(Bernhard Kuhn, MD, PhD, Harvard Children''s Hospital, 61 Binney Street, Enders 1329, Boston MA 02115) Research collaboration with this laboratory involving a study of growth, proliferation and regeneration in the human heart from infancy to senescence.
United States	(Director, Long QT Syndrome Clinic and Windland Smith Rice Sudden Death Genomics Laboratory Mayo Clinic) Research collaboration into molecular changes in hypertrophic cardiomyopathy in human hearts
United States	(Harvard Children's Hospital, Cardiology) Collaboration with Dr Bill Pu working on microRNAs and human heart failure
United States	(Harvard Medical School) working with Prof Paul Allen
United States	(Johns Hopkins University Medical School, Division of Cardiology, Biological Chemistry and Biomedical Engineering) Working with Prof Jennifer Van Eyk on proteomics of failing human hearts
United States	(Lilehei Heart Inst, Division of Cardiology, University of Minnesota) Collaboration with Prof Jennifer Hall working on transcriptomics of failing human hearts
United States	(William Pu, PhD Department of Cardiology, Children''s Hospital Enders 13,300 Longwood Ave., Boston, MA 02115) Research collaboration involving the role of splicing variants of cardiac proteins in human heart failure

Selected publications

Actin-Binding Proteins and Disease

(Springer Science+Business Media, 2008)

Molecular Interactions of Actin; Actin-Myosin Interaction & Actin-Based Regulation

(Springer, 2002)

Publications

By Type

Expand all

Edited Books

Dos Remedios, C., Chhabra, D. (2008). Actin-Binding Proteins and Disease. New York: Springer Science+Business Media.
Dos Remedios, C., Qin, Z., Shi, Y. (2006). The Amazing Human Body:the anatomical display of real human bodies. Australia: Redtail.
Dos Remedios, C., Thomas, D. (2002). Molecular Interactions of Actin; Actin-Myosin Interaction & Actin-Based Regulation. United States: Springer.

Book Chapters

Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
Stefani, M., Tsubakihara, M., Hambly, B., Liew, C., Allen, P., Macdonald, P., Dos Remedios, C. (2008). Actin and its binding proteins in heart failure. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 318-334). New York: Springer Science+Business Media. [More Information]
Chhabra, D., Dos Remedios, C. (2008). Actin: an overview of its structure and function. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 1-16). New York: Springer Science+Business Media.
Dos Remedios, C., Nosworthy, N. (2008). The role of PIP2 in actin, actin-binding proteins and disease. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 290-297). New York: Springer Science+Business Media.
Lui, R., Brown, A., Wu, B., Lin, M., Thompson, J., Braet, F., Dyer, W., Lattimore, J., Macdonald, P., Adelstein, S., Dos Remedios, C. (2008). Use of Antibody Microarrays in the Analysis of Inflammation, Autoimmunity, Viral Infection, and Cancer Metastases. In J. E. Van Eyk and M. J. Dunn (Eds.), Clinical Proteomics: From Diagnosis to Therapy, (pp. 571-592). Weinheim: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]
Dos Remedios, C., Chhabra, D. (2007). Foreword. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. v-vii). New York: Springer Science+Business Media.
Dos Remedios, C., Thomas, D. (2001). An overview of actin structure and actin-binding proteins. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 1-7). Germany: Springer.
Dos Remedios, C., Moens,, P. (2001). Analysis of models of F-Actin using fluorescence resonance energy transfer spectroscopy. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 59-76). Germany: Springer.
Kekic, M., Nosworthy, N., Dedova, I., Collyer, C., Dos Remedios, C. (2001). Regulation of the cytoskeleton assembly: a role for a ternary complex of actin with two actin-binding proteins. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 165-177). Germany: Springer.

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Journals

Kekic, M., Hanson, K., Perumal, A., Solana, G., Rajendran, K., Dash, S., Nicolau, D., Dobroiu, S., Dos Remedios, C. (2024). Biosensing using antibody-modulated motility of actin filaments on myosin-coated surfaces. Biosensors and Bioelectronics, 246, 115879. [More Information]
Wang, L., Tsakiroglou, P., Gonzales, R., Cho, S., Li, A., Dos Remedios, C., Wright, N., Kontrogianni-Konstantopoulos, A. (2024). Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation. JCI Insight, 9(3). [More Information]
Nollet, E., Schuldt, M., Sequeira, V., Binek, A., Pham, T., Schoonvelde, S., Jansen, M., Schomakers, B., van Weeghel, M., Vaz, F., Dos Remedios, C., et al (2024). Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and Precision Medicine, 17(3), 238-253. [More Information]
Li, A., Fang, B., Li, M., Koay, Y., Malecki, C., Hunter, B., Harney, D., Dos Remedios, C., Larance, M., O'Sullivan, J., Lal, S. (2024). Myocardial Posttranscriptional Landscape in Peripartum Cardiomyopathy. Circulation. Heart Failure, 17(12), e011725. [More Information]
Garmany, R., Bos, J., Tester, D., Giudicessi, J., dos Remedios, C., Dasari, S., Nagaraj, N., Nair, A., Johnson, K., Ryan, Z., et al (2023). Multi-Omic Architecture of Obstructive Hypertrophic Cardiomyopathy. Circulation. Genomic and Precision Medicine, 16(2), E003756. [More Information]
Burkart, V., Kowalski, K., Disch, A., Hilfiker-Kleiner, D., Lal, S., dos Remedios, C., Perrot, A., Zeug, A., Ponimaskin, E., Kosanke, M., et al (2023). Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients. Journal of Molecular and Cellular Cardiology, 185, 26-37. [More Information]
Garmany, R., Bos, J., Dasari, S., Johnson, K., Tester, D., Giudicessi, J., dos Remedios, C., Maleszewski, J., Ommen, S., Dearani, J., et al (2023). Proteomic and phosphoproteomic analyses of myectomy tissue reveals difference between sarcomeric and genotype-negative hypertrophic cardiomyopathy. Scientific Reports, 13(1). [More Information]
Algül, S., Dorsch, L., Sorop, O., Vink, A., Michels, M., dos Remedios, C., Dalinghaus, M., Merkus, D., Duncker, D., Kuster, D., et al (2023). The microtubule signature in cardiac disease: etiology, disease stage, and age dependency. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 193(5), 581-595. [More Information]
Taylor, J., Yeung, A., Ashton, A., Faiz, A., Guryev, V., Fang, B., Lal, S., Grosser, M., Dos Remedios, C., Braet, F., Li, A., et al (2023). Transcriptomic Comparison of Human Peripartum and Dilated Cardiomyopathy Identifies Differences in Key Disease Pathways. Journal of Cardiovascular Development and Disease, 10(5). [More Information]
Grosser, M., Lin, H., Wu, M., Zhang, Y., Tipper, S., Venter, D., Lu, J., Dos Remedios, C. (2022). A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning. Biophysical Reviews, 14(1), 381-401. [More Information]
van Wezenbeek, J., Groeneveldt, J., Llucià-Valldeperas, A., van der Bruggen, C., Jansen, S., Smits, A., Smal, R., van Leeuwen, J., Dos Remedios, C., Keogh, A., et al (2022). Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort. Journal Of Heart And Lung Transplantation, 41(4), 445-457. [More Information]
Sequeira, V., Wang, L., Wijnker, P., Kim, K., Pinto, J., Dos Remedios, C., Redwood, C., Knollmann, B., van der Velden, J. (2022). Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy. Journal of Molecular and Cellular Cardiology, 1, 100007. [More Information]
Zhu, Y., Jackson, D., Hunter, B., Beattie, L., Turner, L., Hambly, B., Jeremy, R., Malecki, C., Robertson, E., Li, A., Dos Remedios, C., Richmond, D., Semsarian, C., O'Sullivan, J., Bannon, P., Lal, S. (2022). Models of cardiovascular surgery biobanking to facilitate translational research and precision medicine. ESC Heart Failure, 9(1), 21-30. [More Information]
Li, A., Campbell, K., Lal, S., Ge, Y., Keogh, A., Macdonald, P., Lau, P., Lai, J., Linke, W., Van der Velden, J., Dos Remedios, C., et al (2022). Peripartum cardiomyopathy: a global effort to find the cause and cure for the rare and little understood disease. Biophysical Reviews, 14(1), 369-379. [More Information]
Videira, R., Koop, A., Ottaviani, L., Poels, E., Kocken, J., Dos Remedios, C., Mendes-Ferreira, P., Van De Kolk, K., Du Marchie Sarvaas, G., Lourenço, A., et al (2022). The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload. Cardiovascular Research, 118(12), 2688-2702. [More Information]
Vikhorev, P., Vikhoreva, N., Yeung, W., Li, A., Lal, S., dos Remedios, C., Blair, C., Guglin, M., Campbell, K., Yacoub, M., et al (2022). Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation. Cardiovascular Research, 118(1), 241-253. [More Information]
Burkart, V., Kowalski, K., Aldag-Niebling, D., Beck, J., Frick, D., Holler, T., Radocaj, A., Piep, B., Zeug, A., Hilfiker-Kleiner, D., et al (2022). Transcriptional bursts and heterogeneity among cardiomyocytes in hypertrophic cardiomyopathy. Frontiers in Cardovascular Medicine, 9. [More Information]
Berecz, T., Yiu, A., Vittay, O., Orsolits, B., Mioulane, M., Dos Remedios, C., Ketteler, R., Merkely, B., Apáti, Á., Harding, S., et al (2022). Transcriptional co-activators YAP1–TAZ of Hippo signalling in doxorubicin-induced cardiomyopathy. ESC Heart Failure, 9(1), 224-235. [More Information]
Cranfield, C., Whelan, D., Cox, C., Shearwin, K., Ho, J., Allen, T., Shibuya, R., Hibino, E., Hayashi, K., dos Remedios, C., et al (2021). Announcing the call for the Special Issue on The Australian Society for Biophysics (ASB) - 2021 Meeting"". Biophysical Reviews, 13, 485-486. [More Information]
Sonnenschein, K., Fiedler, J., de Gonzalo-Calvo, D., Xiao, K., Pfanne, A., Just, A., Zwadlo, C., Soltani, S., Bavendiek, U., Kraft, T., Dos Remedios, C., et al (2021). Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy. Scientific Reports, 11(1), 1755. [More Information]
Mouat, M., Coleman, J., Wu, J., dos Remedios, C., Feneley, M., Graham, R., Smith, N. (2021). Involvement of GPR37L1 in murine blood pressure regulation and human cardiac disease pathophysiology. American Journal of Physiology - Heart and Circulatory Physiology, 321(4), H807-H817. [More Information]
Hou, Y., Bai, J., Shen, X., de Langen, O., Li, A., Lal, S., dos Remedios, C., Baddeley, D., Ruygrok, P., Soeller, C., et al (2021). Nanoscale Organisation of Ryanodine Receptors and Junctophilin-2 in the Failing Human Heart. Frontiers in Physiology, 12, 724372. [More Information]
Schuldt, M., Pei, J., Harakalova, M., Dorsch, L., Schlossarek, S., Mokry, M., Knol, J., Pham, T., Schelfhorst, T., Piersma, S., Dos Remedios, C., et al (2021). Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy. Circulation. Heart Failure, 14(1), e007022. [More Information]
Schuldt, M., Dorsch, L., Knol, J., Pham, T., Schelfhorst, T., Piersma, S., Dos Remedios, C., Michels, M., Jimenez, C., Kuster, D., et al (2021). Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy. Frontiers in Cardovascular Medicine, 8, 612215. [More Information]
Sim, C., Phipson, B., Ziemann, M., Rafehi, H., Mills, R., Watt, K., Abu-Bonsrah, K., Kalathur, R., Voges, H., Dinh, D., Dos Remedios, C., Lal, S., et al (2021). Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor. Circulation, 143(16), 1614-1628. [More Information]
Fomin, A., Gärtner, A., Cyganek, L., Tiburcy, M., Tuleta, I., Wellers, L., Folsche, L., Hobbach, A., von Frieling-Salewsky, M., Unger, A., et al (2021). Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations. Science Translational Medicine, 13(618). [More Information]
Tucholski, T., Cai, W., Gregorich, Z., Bayne, E., Mitchell, S., McIlwain, S., de Lange, W., Wrobbel, M., Karp, H., Hite, Z., Lal, S., Li, A., Dos Remedios, C., et al (2020). Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics. Proceedings of the National Academy of Sciences of the United States of America, 117(40), 24691-24700. [More Information]
Auxerre-Plantié, E., Nielsen, T., Grunert, M., Olejniczak, O., Perrot, A., Ozcelik, C., Harries, D., Matinmehr, F., Dos Remedios, C., Mühlfeld, C., et al (2020). Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart. Disease Models & Mechanisms, 13(12), 1-15. [More Information]
Bos, J., Hebl, V., Oberg, A., Sun, Z., Herman, D., Teekakirikul, P., Seidman, J., Seidman, C., dos Remedios, C., Maleszewski, J., et al (2020). Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2–Mediated COVID-19. Mayo Clinic Proceedings, 95(7), 1354-1368. [More Information]
Herwig, M., Kolijn, D., Lódi, M., Hölper, S., Kovács, Á., Papp, Z., Jaquet, K., Haldenwang, P., Dos Remedios, C., Reusch, P., et al (2020). Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D. Frontiers in Physiology, 11, 1-23. [More Information]
Pandzic, E., Morkel, C., Li, A., Cooke, R., Whan, R., dos Remedios, C. (2020). Nanomolar ATP binding to single myosin cross-bridges in rigor: a molecular approach to studying myosin ATP kinetics using single human cardiomyocytes. Biophysical Reviews, 12(4), 1031-1040. [More Information]
Ashna, A., van Helden, D., Dos Remedios, C., Molenaar, P., Laver, D. (2020). Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action. Molecular Pharmacology, 97(4), 250-258. [More Information]
Brayson, D., Holohan, S., Bardswell, S., Arno, M., Lu, H., Jensen, H., Tran, P., Barallobre-Barreiro, J., Mayr, M., Dos Remedios, C., et al (2020). Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association, 9(16), e015342. [More Information]
Nijenkamp, L., Bollen, I., Niessen, H., Dos Remedios, C., Michels, M., Poggesi, C., Ho, C., Kuster, D., van der Velden, J. (2020). Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy. PloS One, 15(5), e0232427. [More Information]
Li, A., Lal, S., Dos Remedios, C. (2019). A step towards understanding the molecular nature of human heart failure: advances using the Sydney Heart Bank collection. Biophysical Reviews, 11(2), 241-244. [More Information]
Walweel, K., Gomez-Hurtado, N., Rebbeck, R., Oo, Y., Beard, N., Molenaar, P., Dos Remedios, C., van Helden, D., Cornea, R., Knollmann, B., et al (2019). Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814. Journal of Molecular and Cellular Cardiology, 130, 96-106. [More Information]
Liu, C., Lim, S., Teo, M., Tan, M., Kulkarni, M., Qiu, B., Li, A., Lal, S., Dos Remedios, C., Tan, N., et al (2019). Collaborative Regulation of LRG1 by TGF-Beta1 and PPAR-Beta/Delta Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis. Circulation. Heart Failure, 12(12), 1-16. [More Information]
Le, T., Pickett, H., Yang, A., Ho, J., Thavapalachandran, S., Igoor, S., Yang, S., Farraha, M., Voges, H., Hudson, J., Dos Remedios, C., Bryan, T., Kizana, E., Chong, J. (2019). Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells. Scientific Reports, 9(1), 1-17. [More Information]
Dos Remedios, C. (2019). Letter from the Editor. Biophysical Reviews, 11(2), 127-128. [More Information]
Ge, Z., Li, A., McNamara, J., Dos Remedios, C., Lal, S. (2019). Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies. Heart Failure Reviews, 24(5), 743-758. [More Information]
Dos Remedios, C., Marrocco, V., Bogomolovas, J., Ehler, E., Yu, J., Gao, C., Lange, S. (2019). PKC and PKN in heart disease. Journal of Molecular and Cellular Cardiology, 128, 212-226. [More Information]
Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M., Hayward, R., Ahmad, S., Vizcay-Barrena, G., Protti, A., Zammit, P., Dos Remedios, C., et al (2019). Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies. JCI Insight, 4(22), 1-19. [More Information]
Dorsch, L., Schuldt, M., Dos Remedios, C., Schinkel, A., de Jong, P., Michels, M., Kuster, D., Brundel, B., van der Velden, J. (2019). Protein quality control activation and microtubule remodeling in hypertrophic cardiomyopathy. Cells, 8(7). [More Information]
Dos Remedios, C. (2019). Recollections of 50 years of research in biophysics: a matter of hard work and luck. Biophysical Reviews, 11(2), 135-137. [More Information]
Piroddi, N., Witjas-Paalberends, E., Ferrara, C., Ferrantini, C., Vitale, G., Scellini, B., Wijnker, P., Sequiera, V., Dooijes, D., Dos Remedios, C., et al (2019). The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM. Journal of General Physiology, 151(1), 18-29. [More Information]
van Heesch, S., Witte, F., Schneider-Lunitz, V., Schulz, J., Adami, E., Faber, A., Kirchner, M., Maatz, H., Blachut, S., Sandmann, C., Dos Remedios, C., et al (2019). The Translational Landscape of the Human Heart. Cell, 178(1), 242-260.e29. [More Information]
Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Dos Remedios, C., et al (2019). TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation. EMBO Molecular Medicine, 11(10), e10018. [More Information]
Kanellis, V., Dos Remedios, C. (2018). A review of heavy metal cation binding to deoxyribonucleic acids for the creation of chemical sensors. Biophysical Reviews, 10(5), 1401-1414. [More Information]
Gotzmann, M., Grabbe, S., Schone, D., von Frieling-Salewsky, M., Dos Remedios, C., Strauch, J., Bechtel, M., Dietrich, J., Tannapfel, A., Mugge, A., et al (2018). Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis. JACC: Basic to Translational Science, 3(3), 335-346. [More Information]
Dos Remedios, C. (2018). An historical perspective of the discovery of titin filaments -Part 2. Biophysical Reviews, 10(4), 1201-1203. [More Information]
Montag, J., Kowalski, K., Makul, M., Ernstberger, P., Radocaj, A., Beck, J., Becker, E., Tripathi, S., Keyser, B., Muhlfeld, C., Dos Remedios, C., et al (2018). Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy. Frontiers in Physiology, 9(359), 1-15. [More Information]
da Silva Goncalves, B., van Der Bruggen, C., Kurakula, K., Sun, X., Casali, K., Casali, A., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., et al (2018). Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension. Circulation, 137(9), 910-924. [More Information]
Dos Remedios, C., Lal, S., Li, A., McNamara, J., Keogh, A., MacDonald, P., Cooke, R., Ehler, E., Knoll, R., Marston, S., et al (2018). Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease. Biophysical Reviews, 10(3), 941. [More Information]
Iorga, B., Schwanke, K., Weber, N., Wendland, M., Greten, S., Piep, B., Dos Remedios, C., Martin, U., Zweigerdt, R., Kraft, T., et al (2018). Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms. Frontiers in Physiology, 8(1111), 1-20. [More Information]
Dos Remedios, C., Li, A. (2018). Editorial for issue #1 2018. Biophysical Reviews, 10(1), 1-2. [More Information]
Martin-Garrido, A., Biesiadecki, B., Salhi, H., Shaifta, Y., Dos Remedios, C., Ayuz-Guner, S., Cai, W., Ge, Y., Avkiran, M., Kentish, J. (2018). Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis. Journal of Biological Chemistry, 293(22), 8588-8599. [More Information]
Dos Remedios, C., Li, A., Lal, S. (2018). Non-sarcomeric causes of heart failure: a Sydney Heart Bank perspective. Biophysical Reviews, 10(4), 949-954. [More Information]
Coleman, J., Mouat, M., Wu, J., Jancovski, N., Bassi, J., Chan, A., Humphreys, D., Mrad, N., Yu, Z., Ngo, T., Dos Remedios, C., et al (2018). Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control. Biology of Sex Differences, 9(1), 1-13. [More Information]
Le, T., Pickett, H., Dos Remedios, C., Barbaro, P., Kizana, E., Chong, J. (2018). Platelet-Derived Growth Factor Receptor-Alpha expressing cardiac progenitor cells can be derived from previously cryopreserved human heart samples. Stem Cells and Development, 27(3), 184-198. [More Information]
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Lal, S., Li, A., Dos Remedios, C. (2016). Limitations in Translating Animal Studies to Humans in Cardiovascular Disease. Journal of Cardiovascular Translational Research, 9(2), 165-166. [More Information]
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Lal, S., Nguyen, L., Tezone, R., Ponten, F., Odeberg, J., Li, A., Dos Remedios, C. (2016). Tissue microarray profiling in human heart failure. Proteomics, 16(17), 2319-2326. [More Information]
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Lal, S., Li, A., Allen, D., Allen, P., Bannon, P., Cartmill, T., Cooke, R., Farnswoirth, A., Keogh, A., Dos Remedios, C. (2015). Best practice BioBanking of human heart tissue. Biophysical Reviews, 7(4), 399-406. [More Information]
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Chahine, M., Mioulane, M., Sikkel, M., Oâ€™Gara, P., Dos Remedios, C., Pierce, G., Lyon, A., Foldes, G., Harding, S. (2015). Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts. Cardiovascular Research, 105(1), 31-43. [More Information]
Marston, S., Montgiraud, C., Munster, A., Copeland, O., Choi, O., Dos Remedios, C., Messer, A., Ehler, E., KnÃ¶ll, R. (2015). OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency. PloS One, 10(9), 1-10. [More Information]
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Li, A., Dos Remedios, C. (2015). Special Issue on human heart failure. Biophysical Reviews, 7(1), 1-3. [More Information]
Kagemoto, T., Li, A., Dos Remedios, C., Ishiwata, S. (2015). Spontaneous oscillatory contraction (SPOC) in cardiomyocytes. Biophysical Reviews, 7(1), 15-24. [More Information]
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Lin, M., Ho, J., Harrison, L., Dos Remedios, C., Adelstein, S. (2013). An antibody-based leukocyte-capture microarray for the diagnosis of systemic lupus erythematosus. PloS One, 8(3), 1-8. [More Information]
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Velonas, V., Woo, H., Dos Remedios, C., Assinder, S. (2013). Current Status of Biomarkers for Prostate Cancer. International Journal of Molecular Sciences, 14(6), 11034-11060. [More Information]
Kotter, S., Gout, L., Von Frieling-Salewsky, M., Muller, A., Helling, S., Marcus, K., Dos Remedios, C., Linke, W., Kruger, M. (2013). Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts. Cardiovascular Research, 99(4), 648-656. [More Information]
Memo, M., Leung, M., Ward, D., Dos Remedios, C., Morimoto, S., Zhang, L., Ravenscroft, G., McNamara, E., Nowak, K., Marston, S., et al (2013). Familial dilated cardiomyopathy mutations uncouple troponin l phosphorylation from changes in myofibrillar Ca2+ sensitivity. Cardiovascular Research, 99(1), 65-73. [More Information]
Hall, D., Dos Remedios, C. (2013). Foreword to the biophysics of protein-protein and protein-ligand interactions in dilute and crowded media - a special issue in honor of Allen Minton's 70th birthday. Biophysical Reviews, 5(2), 57-60. [More Information]
Cordell, H., Bentham, J., Topf, A., Zelenika, D., Heath, S., Mamasoula, C., Cosgrove, C., Blue, G., Granados-Riveron, J., Setchfield, K., Dos Remedios, C., Winlaw, D., et al (2013). Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. Nature Genetics, 45(7), 822-824. [More Information]
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Li, A., Estigoy, C., Raftery, M., Cameron, D., Odeberg, J., Ponten, F., Lal, S., Dos Remedios, C. (2013). Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank. Heart, Lung, and Circulation, 22(10), 819-826. [More Information]
Wijnker, P., Foster, D., Tsao, A., Frazier, A., Dos Remedios, C., Murphy, A., Stienen, G., van der Velden, J. (2013). Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes. American Journal of Physiology - Heart and Circulatory Physiology, 304(2), H260-H268. [More Information]
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Kuster, D., Mulders, J., ten Cate, F., Michels, M., Dos Remedios, C., da Costa Martins, P., van der Velden, J., Oudejans, C. (2013). MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. Journal of Molecular and Cellular Cardiology, 65, 59-66. [More Information]
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Wiggers, W., Olson, W., Dos Remedios, C. (2012). Computational opportunities for remote collaboration and capacity building afforded by Web 2.0 and cloud computing. Biophysical Reviews, 4(3), 153-160. [More Information]
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Dos Remedios, C., Nakamura, H. (2012). Editorial. Biophysical Reviews, 4(3), 149-151. [More Information]
Ling, L., Khammy, O., Byrne, M., Amirahmadi, F., Foster, A., Li, G., Zhang, L., Dos Remedios, C., Chen, C., Kaye, D. (2012). Irregular rhythm adversely influences calcium handling in ventricular myocardium. Circulation. Heart Failure, 5(6), 786-793. [More Information]
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Li, A., Ponten, F., Dos Remedios, C. (2012). The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. Proteomics, 12(2), 203-225. [More Information]
Polden, J., McManus, C., Dos Remedios, C., Dunn, M. (2011). A 2-D gel reference map of the basic human heart proteome. Proteomics, 11(17), 3582-3586. [More Information]
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Morales, M., Dos Remedios, C. (2011). Biophysical educational experiment: science and goodwill in Latin America and Africa. Biophysical Reviews, 3, 101-106. [More Information]
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Hirsh, S., Nosworthy, N., Kondyurin, A., Dos Remedios, C., McKenzie, D., Bilek, M. (2011). Linker-free covalent thermophilic b-glucosidase functionalized polymeric surfaces. Journal of Materials Chemistry, 21, 17832-17841. [More Information]
Maeder, M., Khammy, O., Dos Remedios, C., Kaye, D. (2011). Myocardial and Systemic Iron Depletion in Heart Failure: Implications for Anemia Accompanying Heart Failure. Journal of the American College of Cardiology, 58(5), 474-480. [More Information]
Wijnker, P., Boknik, P., Gergs, U., Muller, F., Neumann, J., Dos Remedios, C., Schmitz, W., Sindermann, J., Stienen, G., van der Velden, J., et al (2011). Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium. Journal Of Muscle Research And Cell Motility, 32(3), 221-233. [More Information]
Wolfe, J., Ishiwata, S., Braet, F., Whan, R., Su, Y., Lal, S., Dos Remedios, C. (2011). SPontaneous Oscillatory Contraction (SPOC): auto-oscillations observed in striated muscle at partial activation. Biophysical Reviews, 3(2), 53-62. [More Information]
Changsirivathanathamrong, D., Wang, Y., Rajbhandari, D., Maghzal, G., Mak, W., Woolfe, C., Duflou, J., Gebski, V., Dos Remedios, C., Celermajer, D., Stocker, R. (2011). Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. Critical Care Medicine, 39(12), 2678-2683. [More Information]
Hirsh, S., Bilek, M., Nosworthy, N., Kondyurin, A., Dos Remedios, C., McKenzie, D. (2010). A Comparison of Covalent Immobilization and Physical Adsorption of a Cellulase Enzyme Mixture. Langmuir, 26(17), 14380-14388. [More Information]
Ho, J., Lin, M., Adelstein, S., Dos Remedios, C. (2010). Customising an antibody leukocyte capture microarray for systemic lupus erythematosus: Beyond biomarker discovery. Proteomics - Clinical Applications, 4(2), 179-189. [More Information]
Kooij, V., Saes, M., Jaquet, K., Zaremba, R., Foster, D., Murphy, A., Dos Remedios, C., van der Velden, J., Stienen, G. (2010). Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background. Journal of Molecular and Cellular Cardiology, 48(5), 954-963. [More Information]
Iskratsch, T., Lange, S., Dwyer, J., Kho, A., Dos Remedios, C., Ehler, E. (2010). Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance. The Journal of Cell Biology, 191(6), 1159-1172. [More Information]
Kong, S., Hu, Y., Ho, J., Ikeda, S., Polster, S., John, R., Hall, J., Bisping, E., Pieske, B., Dos Remedios, C., et al (2010). Heart Failure-Associated Changes in RNA Splicing of Sarcomere Genes. Circulation: Cardiovascular Genetics, 3(2), 138-146. [More Information]
Kwok, D., Tong, L., Yeung, C., Dos Remedios, C., Chu, P. (2010). Hybrid plasma surface modification and ion implantation of biopolymers. Surface & Coatings Technology, 204(18-19), 2892-2897. [More Information]
Lal, S., Dos Remedios, C. (2010). Is There a Connection between Ablation of Atrial Fibrillation and Reduced Apoptosis? Cardiology, 117(3), 161-2. [More Information]
Hamdani, N., Borbely, A., Veenstra, S., Kooij, V., Vrydag, W., Zaremba, R., Dos Remedios, C., Niessen, H., Michel, M., Paulus, W., et al (2010). More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease. Journal Of Muscle Research And Cell Motility, 31(4), 289-301. [More Information]
Hoskins, A., Jacques, A., Bardswell, S., McKenna, W., Tsang, V., Dos Remedios, C., Ehler, E., Adams, K., Jalilzadeh, S., Avkiran, M., et al (2010). Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 49(5), 737-745. [More Information]
Lu, Z., Xu, X., Hu, X., Lee, S., Traverse, J., Zhu, G., Fassett, J., Tao, Y., Zhang, P., Dos Remedios, C., et al (2010). Oxidative stress regulates left ventricular PDE5 expression in the failing heart. Circulation, 121(13), 1474-1483. [More Information]
Robinson, A., Dunn, M., McCormack, A., Dos Remedios, C., Rose, M. (2010). Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization. Journal of Molecular and Cellular Cardiology, 49(3), 370-379. [More Information]
Kooij, V., Boontje, N., Zaremba, R., Jaquet, K., Dos Remedios, C., Stienen, G., van der Velden, J. (2010). Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca(2+) sensitivity in human myocardium. Basic Research in Cardiology, 105(2), 289-300. [More Information]
Ho, J., Stefani, M., Dos Remedios, C., Charleston, M. (2009). A model selection approach to discover age-dependent gene expression patterns using quantile regression models. BMC Genomics, 10(Suppl 3), S16-1-S16-18. [More Information]
van Dijk, S., Holewijn, R., Tebeest, A., Dos Remedios, C., Stienen, G., van der Velden, J. (2009). A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients. Journal Of Muscle Research And Cell Motility, 30(7-Aug), 299-302. [More Information]
Van Dijk, S., Dooijes, D., Dos Remedios, C., Michels, M., Lamers, J., Winegrad, S., Schlossarek, S., Carrier, L., ten Cate, F., Stienen, G., et al (2009). Cardiac myosin-binding protein C mutations and hypertrophic ardiomyopathy haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction. Circulation, 119(11), 1473-1483. [More Information]
Estigoy, C., Ponten, F., Odeberg, J., Herbert, B., Guilhaus, M., Charleston, M., Ho, J., Cameron, D., Dos Remedios, C. (2009). Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts. Biophysical Reviews, 1(1), 43-49. [More Information]
Kruger, M., Kotter, S., Grutzner, A., Lang, P., Andresen, C., Redfield, M., Butt, E., Dos Remedios, C., Linke, W. (2009). Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs. Circulation Research, 104(1), 87-94. [More Information]
Dos Remedios, C., Yamane, M., Hughes, J., Stefani, M., Fukuda, N., Kurihara, S., Steenman, M., Ishiwata, S. (2009). SPOC: A Functional Assay of Failing and Non-Failing Human Cardiomyocytes. Biophysical Journal, 96(3 Suppl 1), 224a.
Dos Remedios, C., Yamane, M., Robinson, J., Hughes, J., Stefani, M., Fukuda, N., Kurihara, S., Steenman, M., Ishiwata, S. (2009). Spontaneous Oscillatory Contraction: A Functional Assay of Contractile Function of Human Heart Samples Stored at -190 ÂºC. Heart, Lung, and Circulation, 18(3), S311-S311.
Messer, A., Gallon, C., McKenna, W., Dos Remedios, C., Marston, S. (2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. Proteomics - Clinical Applications, 3, 1371-1382. [More Information]
Lal, S., Brown, A., Nguyen, L., Braet, F., Dyer, W., Dos Remedios, C. (2009). Using antibody arrays to detect microparticles from acute coronary syndrome patients based on Cluster of Differentiation (CD) antigen expression. Molecular and Cellular Proteomics, 8(4), 799-804. [More Information]
Martinez-Neira, R., Dos Remedios, C., Mackay, I. (2008). An actin-myosin functional assay for analysis of smooth muscle (anti-microfilament) autoantibodies in human plasma. Journal of Immunological Methods, 338(1-2), 63-66. [More Information]
Ho, J., Stefani, M., Dos Remedios, C., Charleston, M. (2008). Differential variability analysis of gene expression and its application to human diseases. Bioinformatics, 24(13), i390-i398. [More Information]
Ho, J., Koundinya, R., Caetano, T., Dos Remedios, C., Charleston, M. (2008). Inferring differential leukocyte activity from antibody microarrays using a latent variable model. Genome Informatics, 21(1), 126-137. [More Information]
Hamdani, N., Waard, M., Messer, A., Boontje, N., Kooij, V., van Dijk, S., Versteilen, A., Lamberts, R., Merkus, D., Dos Remedios, C., et al (2008). Myofilament dysfunction in cardiac disease from mice to men. Journal Of Muscle Research And Cell Motility, 29(6-Aug), 189-201. [More Information]
Hamdani, N., Kooij, V., van Dijk, S., Merkus, D., Paulus, W., Dos Remedios, C., Duncker, D., Stienen, G., van der Velden, J. (2008). Sarcomeric dysfunction in heart failure. Cardiovascular Research, 77(4), 649-658. [More Information]
Fermin, D., Barac, A., Lee, S., Polster, S., Hannenhalli, S., Bergemann, T., Grindle, S., Dyke, D., Pagani, F., Dos Remedios, C., et al (2008). Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure. Circulation: Cardiovascular Genetics, 1(2), 117-125. [More Information]
Brown, A., Lattimore, J., McGrady, M., Sullivan, D., Dyer, W., Braet, F., Dos Remedios, C. (2008). Stable and unstable angina: Identifying novel markers on circulating leukocytes. Proteomics - Clinical Applications, 2, 90-98. [More Information]
Dos Remedios, C. (2007). New and Notable: The regulation of muscle contraction: As in life, it keeps getting more complex. Biophysical Journal, 93(12), 4097-8. [More Information]
Gan, B., Nosworthy, N., McKenzie, D., Dos Remedios, C., Bilek, M. (2007). Plasma immersion ion implantation treatment of polyethylene for enhanced binding of active horseradish peroxidase. Journal of Biomedical Materials Research A, 85A(3), 605-610. [More Information]
Ho, J., Nosworthy, N., Bilek, M., Gan, B., McKenzie, D., Chu, P., Dos Remedios, C. (2007). Plasma-treated polyethylene surfaces for improved binding of active protein. Plasma Processes and Polymers, 4(5), 583-590. [More Information]
Zhang, L., Merkus, D., Hamdani, N., Lamers, J., Paulus, W., Dos Remedios, C., Duncker, D., Stienen, G., van der Velden, J. (2007). Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies. Proteomics - Clinical Applications, 1, 1285-1290. [More Information]
Nicolau, D., Solana, G., Kekic, M., Fulga, F., Mahanivong, C., Wright, S., Dos Remedios, C. (2007). Surface Hydrophobicity modulates the operation of actomyosin-based dynamic nanodevices. Langmuir, 23(21), 10846-10854. [More Information]
Narolska, N., Piroddi, N., Belus, A., Boontje, N., Scellini, B., Deppermann, S., Zaremba, R., Musters, R., Dos Remedios, C., Jaquet, K., Murphy, A., et al (2006). Impaired Diastolic Function After Exchange of Endogenous Troponin I with C-Terminal Truncated Troponin I in Human Cardiac Muscle. Circulation Research, 99(9), 1012-1020. [More Information]
Gorbatyuk, V., Nosworthy, N., Robson, S., Bains, N., Maciejewski, M., Dos Remedios, C., King, G. (2006). Mapping the phosphoinositide-binding site on chick cofilin explains how PIP2 regulates the cofilin-actin interaction. Molecular Cell, 24(4), 511-522. [More Information]
Steel, B., McKenzie, D., Bilek, M., Nosworthy, N., Dos Remedios, C. (2006). Nanosecond responses of proteins to ultra-high temperature pulses. Biophysical Journal, 91(6), L66-L68. [More Information]
Dedova, I., Nikolaeva, O., Safer, D., De La Cruz, E., Dos Remedios, C. (2006). Thymosin beta4 induces a conformational change in actin monomers. Biophysical Journal, 90(3), 985-992. [More Information]
Martinez-Neira, R., Kekic, M., Nicolau, D., Dos Remedios, C. (2005). A novel biosensor for mercuric ions based on motor proteins. Biosensors and Bioelectronics, 20(7), 1428-1432. [More Information]
Chhabra, D., Dos Remedios, C. (2005). Cofilin, actin and their complex observed in vivo using fluorescence resonance energy transfer. Biophysical Journal, 89(3), 1902-1908. [More Information]
Chhabra, D., Dos Remedios, C. (2005). Intracellular fluorescence resonance energy transfer. Biophysical Journal, 89, 1902-1908.
Jiang, L., Bardini, M., Keogh, A., Dos Remedios, C., Burnstock, G. (2005). P2X1 receptors are closely associated with connexin 43 in human ventricular myocardium. International Journal of Cardiology, 98(2), 291-297. [More Information]
Chhabra, D., Nosworthy, N., Dos Remedios, C. (2005). The N-terminal fragment of gelsolin inhibits the interaction of DNase I with isolated actin, but not with the cofilin-actin complex. Proteomics, 5(12), 3131-3136. [More Information]
Steel, B., Bilek, M., Dos Remedios, C., McKenzie, D. (2004). Apparatus For Exposing Cell Membranes To Rapid Temperature Transients. European Biophysics Journal, 33(2), 117-120. [More Information]
Tsubakihara, M., Williams, N., Keogh, A., Dos Remedios, C. (2004). Comparison Of Gene Expression Between Left Atria And Left Ventricles From Non-Diseased Humans. Proteomics, 4(1), 261-270. [More Information]
Dedova, I., Dos Remedios, C. (2004). Conformational changes of actin induced by strong or weak myosin subfragment-1 binding. Tsitologiya, 46(8), 719-734. [More Information]
Borovikov, Y., Dedova, I., Dos Remedios, C., Vikhoreva, N., Vikhorev, P., Avrova, S., Hazlett, T., Van Der Meer, B. (2004). Fluorescence Depolarization Of Actin Filaments In Reconstructed Myofibers: The Effect Of S1 Or pPDM-S1 On Movements Of Distinct Areas Of Actin. Biophysical Journal, 86(5), 3020-3029. [More Information]
Lal, S., Lui, R., Nguyen, L., Macdonald, P., Denyer, G., Dos Remedios, C. (2004). Increases In Leukocyte Cluster Of Differentiation Antigen Expression During Cardiopulmonary Bypass In Patients Undergoing Heart Transplantation. Proteomics, 4(7), 1918-1926. [More Information]
Dedova, I., Nikolaeva, O., Mikhailova, V., Dos Remedios, C., Levitsky, D. (2004). Two Opposite Effects Of Cofilin On The Thermal Unfolding Of F-Actin: A Differential Scanning Calorimetric Study. Biophysical Chemistry, 110(1-2), 119-128. [More Information]
Dos Remedios, C., Chhabra, D., Kekic, M., Dedova, I., Tsubakihara, M., Berry, A., Nosworthy, N. (2003). Actin binding proteins: Regulation of cytoskeletal microfilaments. Physiological Reviews, 83, 433-473. [More Information]
Ng, D., Court, N., Dos Remedios, C., Bogoyevitch, M. (2003). Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts. Cardiovascular Research, 57, 333-346. [More Information]
Dunn, T., Heller, C., McCarthy, S., Dos Remedios, C. (2003). Anatomical study of the "Trochanteric Bursa". Clinical Anatomy, 16(3), 233-240. [More Information]
Steel, B., Bilek, M., Dos Remedios, C., McKenzie, D. (2003). Apparatus for exposing cell membranes to rapid temperature transients. European Biophysics Journal, 11, 117-120. [More Information]
Jiang, L., Huang, Y., Hunyor, S., Dos Remedios, C. (2003). Cardiomyocyte apoptosis is associated with increased wall stress in chronic failing left ventricle. European Heart Journal, 24, 742-751. [More Information]
Dos Remedios, C., Liew, C., Allen, P., Winslow, R., Van Eyk, J., Dunn, M. (2003). Genomics, proteomics and bioinformatics of human heart failure. Journal Of Muscle Research And Cell Motility, 24(4-6), 251-260. [More Information]
Steel, B., Bilek, M., McKenzie, D., Dos Remedios, C. (2002). A technique for microsecond heating & cooling of a thin (submicron) biological sample. European Biophysics Journal, 31(5), 378-382. [More Information]
Lal, S., Christopherson, R., Dos Remedios, C. (2002). Antibody arrays: an embryonic but rapidly growing technology. Drug Discovery Today, 7(18 Supplement), S143-S149. [More Information]
Court, N., Dos Remedios, C., Cordell, J., Bogoyevitch, M. (2002). Cardiac expression & subcellular localization of the p38 Mitogen-activated protein kinase member, stress-activated protein kinases-3 (SAPK3). Journal of Molecular and Cellular Cardiology, 34(4), 413-426. [More Information]
Dedova, I., Dedov, V., Nosworthy, N., Hambly, B., Dos Remedios, C. (2002). Cofilin and DNase 1 affect the conformation of the small domain of actin. Biophysical Journal, 82, 3134-3143. [More Information]
Heller, C., Marucci, D., Dunn, T., Barr, E., Houang, M., Dos Remedios, C. (2002). Inguinal canal 'Lipoma'. Clinical Anatomy, 15(4), 280-285. [More Information]
Bains, N., Gorbatyuk, V., Nosworthy, N., Robson, S., Maciejewski, M., Dos Remedios, C., King, G. (2002). Letter to the Editor: Backbone and side-chain 1H, 15N, and 13C assignments for chick cofilin. Journal of Biomolecular NMR, 22(2), 193-194.
Mahanivong, C., Wright, J., Kekic, M., Pham, D., Dos Remedios, C., Nicolau, D. (2002). Manipulation of the motility of protein molecular motors on microfabricated substrates. Biomedical Microdevices, 4(2), 111-116. [More Information]
Chhabra, D., Bao, B., Dos Remedios, C. (2002). The distribution of cofilin and DNase I in vivo. Cell Research, 12(3-4), 207-214. [More Information]
Heinke, M., Yao, M., Chang, D., Einstein, R., Dos Remedios, C. (2001). Apoptosis of ventricular and atrial myocytes from pacing-induced canine heart failure. Cardiovascular Research, 49 (1), 127-134. [More Information]
Jiang, L., Tsubakihara, M., Heinke, M., Phillips, W., Dos Remedios, C., Nosworthy, N., Yao, M. (2001). Heart failure and apoptosis: Electrophoretic methods support data from micro- and macro-arrays. A critical review of genomics and proteomics. Proteomics, 1 (12), 1481-1488.
Belov, L., de la Vega, O., Dos Remedios, C., Christopherson, R., Mulligan,, S. (2001). Immunophenotyping of leukemias using a cluster of differentiation antibody microarray. Cancer Research, 61(11), 4483-4489.
Berry, D., Dos Remedios, C., Keogh, A. (2001). Nuclear membrane proteins in failing human dilated cardiomyopathy. Proteomics, 1 (12), 1507-1512. [More Information]
Nosworthy, N., Kekic, M., Dos Remedios, C. (2001). The affinity of chick cofilin for actin increases when actin is complexed with DNase 1: Formation of a cofilin-actin-DNase 1 ternary complex. Proteomics, 1 (12), 1513-1518.

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Conferences

Dos Remedios, C., McKenzie, D., Boswell, R., Lui, R., Bilek, M., Charles, C., Ramdutt, D. (2006). Development of the nanotiter plate for use in antibody and cell array technologies. SPIE - Biomedical Applications of Micro- and Nano-engineering, Australia: SPIE Proceedings.
Kekic, M., Dos Remedios, C., Martinez, R., Nicolau, D. (2005). An acto/myosin in vitro motility assay as a motion based sensor. Biophysical Society 49th Annual Meeting, Bethesda, MD: Biophysical Society.
Lui, R., Tsubakihara, M., Macdonald, P., Hayward, C., Dos Remedios, C. (2005). Analysing inflammation in heart failure using microarray platforms. 27th Annual Meeting of the American Section of the International Society of Heart Research (ISHR), United Kingdom: Academic Press.
Thordarson, P., Bilek, M., McKenzie, D., Nosworthy, N., Davies, K., Morrow, R., Gan, B., Dos Remedios, C. (2005). Functional Attachment of Horse Radish Peroxidase to Plasma Treated Surfaces. Smart Materials III, : SPIE Press.

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2024

Kekic, M., Hanson, K., Perumal, A., Solana, G., Rajendran, K., Dash, S., Nicolau, D., Dobroiu, S., Dos Remedios, C. (2024). Biosensing using antibody-modulated motility of actin filaments on myosin-coated surfaces. Biosensors and Bioelectronics, 246, 115879. [More Information]
Wang, L., Tsakiroglou, P., Gonzales, R., Cho, S., Li, A., Dos Remedios, C., Wright, N., Kontrogianni-Konstantopoulos, A. (2024). Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation. JCI Insight, 9(3). [More Information]
Nollet, E., Schuldt, M., Sequeira, V., Binek, A., Pham, T., Schoonvelde, S., Jansen, M., Schomakers, B., van Weeghel, M., Vaz, F., Dos Remedios, C., et al (2024). Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and Precision Medicine, 17(3), 238-253. [More Information]
Li, A., Fang, B., Li, M., Koay, Y., Malecki, C., Hunter, B., Harney, D., Dos Remedios, C., Larance, M., O'Sullivan, J., Lal, S. (2024). Myocardial Posttranscriptional Landscape in Peripartum Cardiomyopathy. Circulation. Heart Failure, 17(12), e011725. [More Information]

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2023

Garmany, R., Bos, J., Tester, D., Giudicessi, J., dos Remedios, C., Dasari, S., Nagaraj, N., Nair, A., Johnson, K., Ryan, Z., et al (2023). Multi-Omic Architecture of Obstructive Hypertrophic Cardiomyopathy. Circulation. Genomic and Precision Medicine, 16(2), E003756. [More Information]
Burkart, V., Kowalski, K., Disch, A., Hilfiker-Kleiner, D., Lal, S., dos Remedios, C., Perrot, A., Zeug, A., Ponimaskin, E., Kosanke, M., et al (2023). Nonsense mediated decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients. Journal of Molecular and Cellular Cardiology, 185, 26-37. [More Information]
Garmany, R., Bos, J., Dasari, S., Johnson, K., Tester, D., Giudicessi, J., dos Remedios, C., Maleszewski, J., Ommen, S., Dearani, J., et al (2023). Proteomic and phosphoproteomic analyses of myectomy tissue reveals difference between sarcomeric and genotype-negative hypertrophic cardiomyopathy. Scientific Reports, 13(1). [More Information]
Algül, S., Dorsch, L., Sorop, O., Vink, A., Michels, M., dos Remedios, C., Dalinghaus, M., Merkus, D., Duncker, D., Kuster, D., et al (2023). The microtubule signature in cardiac disease: etiology, disease stage, and age dependency. Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, 193(5), 581-595. [More Information]
Taylor, J., Yeung, A., Ashton, A., Faiz, A., Guryev, V., Fang, B., Lal, S., Grosser, M., Dos Remedios, C., Braet, F., Li, A., et al (2023). Transcriptomic Comparison of Human Peripartum and Dilated Cardiomyopathy Identifies Differences in Key Disease Pathways. Journal of Cardiovascular Development and Disease, 10(5). [More Information]

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2022

Grosser, M., Lin, H., Wu, M., Zhang, Y., Tipper, S., Venter, D., Lu, J., Dos Remedios, C. (2022). A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning. Biophysical Reviews, 14(1), 381-401. [More Information]
van Wezenbeek, J., Groeneveldt, J., Llucià-Valldeperas, A., van der Bruggen, C., Jansen, S., Smits, A., Smal, R., van Leeuwen, J., Dos Remedios, C., Keogh, A., et al (2022). Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort. Journal Of Heart And Lung Transplantation, 41(4), 445-457. [More Information]
Sequeira, V., Wang, L., Wijnker, P., Kim, K., Pinto, J., Dos Remedios, C., Redwood, C., Knollmann, B., van der Velden, J. (2022). Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy. Journal of Molecular and Cellular Cardiology, 1, 100007. [More Information]
Zhu, Y., Jackson, D., Hunter, B., Beattie, L., Turner, L., Hambly, B., Jeremy, R., Malecki, C., Robertson, E., Li, A., Dos Remedios, C., Richmond, D., Semsarian, C., O'Sullivan, J., Bannon, P., Lal, S. (2022). Models of cardiovascular surgery biobanking to facilitate translational research and precision medicine. ESC Heart Failure, 9(1), 21-30. [More Information]
Li, A., Campbell, K., Lal, S., Ge, Y., Keogh, A., Macdonald, P., Lau, P., Lai, J., Linke, W., Van der Velden, J., Dos Remedios, C., et al (2022). Peripartum cardiomyopathy: a global effort to find the cause and cure for the rare and little understood disease. Biophysical Reviews, 14(1), 369-379. [More Information]
Videira, R., Koop, A., Ottaviani, L., Poels, E., Kocken, J., Dos Remedios, C., Mendes-Ferreira, P., Van De Kolk, K., Du Marchie Sarvaas, G., Lourenço, A., et al (2022). The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload. Cardiovascular Research, 118(12), 2688-2702. [More Information]
Vikhorev, P., Vikhoreva, N., Yeung, W., Li, A., Lal, S., dos Remedios, C., Blair, C., Guglin, M., Campbell, K., Yacoub, M., et al (2022). Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation. Cardiovascular Research, 118(1), 241-253. [More Information]
Burkart, V., Kowalski, K., Aldag-Niebling, D., Beck, J., Frick, D., Holler, T., Radocaj, A., Piep, B., Zeug, A., Hilfiker-Kleiner, D., et al (2022). Transcriptional bursts and heterogeneity among cardiomyocytes in hypertrophic cardiomyopathy. Frontiers in Cardovascular Medicine, 9. [More Information]
Berecz, T., Yiu, A., Vittay, O., Orsolits, B., Mioulane, M., Dos Remedios, C., Ketteler, R., Merkely, B., Apáti, Á., Harding, S., et al (2022). Transcriptional co-activators YAP1–TAZ of Hippo signalling in doxorubicin-induced cardiomyopathy. ESC Heart Failure, 9(1), 224-235. [More Information]

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2021

Cranfield, C., Whelan, D., Cox, C., Shearwin, K., Ho, J., Allen, T., Shibuya, R., Hibino, E., Hayashi, K., dos Remedios, C., et al (2021). Announcing the call for the Special Issue on The Australian Society for Biophysics (ASB) - 2021 Meeting"". Biophysical Reviews, 13, 485-486. [More Information]
Sonnenschein, K., Fiedler, J., de Gonzalo-Calvo, D., Xiao, K., Pfanne, A., Just, A., Zwadlo, C., Soltani, S., Bavendiek, U., Kraft, T., Dos Remedios, C., et al (2021). Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy. Scientific Reports, 11(1), 1755. [More Information]
Mouat, M., Coleman, J., Wu, J., dos Remedios, C., Feneley, M., Graham, R., Smith, N. (2021). Involvement of GPR37L1 in murine blood pressure regulation and human cardiac disease pathophysiology. American Journal of Physiology - Heart and Circulatory Physiology, 321(4), H807-H817. [More Information]
Hou, Y., Bai, J., Shen, X., de Langen, O., Li, A., Lal, S., dos Remedios, C., Baddeley, D., Ruygrok, P., Soeller, C., et al (2021). Nanoscale Organisation of Ryanodine Receptors and Junctophilin-2 in the Failing Human Heart. Frontiers in Physiology, 12, 724372. [More Information]
Schuldt, M., Pei, J., Harakalova, M., Dorsch, L., Schlossarek, S., Mokry, M., Knol, J., Pham, T., Schelfhorst, T., Piersma, S., Dos Remedios, C., et al (2021). Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy. Circulation. Heart Failure, 14(1), e007022. [More Information]
Schuldt, M., Dorsch, L., Knol, J., Pham, T., Schelfhorst, T., Piersma, S., Dos Remedios, C., Michels, M., Jimenez, C., Kuster, D., et al (2021). Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy. Frontiers in Cardovascular Medicine, 8, 612215. [More Information]
Sim, C., Phipson, B., Ziemann, M., Rafehi, H., Mills, R., Watt, K., Abu-Bonsrah, K., Kalathur, R., Voges, H., Dinh, D., Dos Remedios, C., Lal, S., et al (2021). Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor. Circulation, 143(16), 1614-1628. [More Information]
Fomin, A., Gärtner, A., Cyganek, L., Tiburcy, M., Tuleta, I., Wellers, L., Folsche, L., Hobbach, A., von Frieling-Salewsky, M., Unger, A., et al (2021). Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations. Science Translational Medicine, 13(618). [More Information]

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2020

Tucholski, T., Cai, W., Gregorich, Z., Bayne, E., Mitchell, S., McIlwain, S., de Lange, W., Wrobbel, M., Karp, H., Hite, Z., Lal, S., Li, A., Dos Remedios, C., et al (2020). Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics. Proceedings of the National Academy of Sciences of the United States of America, 117(40), 24691-24700. [More Information]
Auxerre-Plantié, E., Nielsen, T., Grunert, M., Olejniczak, O., Perrot, A., Ozcelik, C., Harries, D., Matinmehr, F., Dos Remedios, C., Mühlfeld, C., et al (2020). Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart. Disease Models & Mechanisms, 13(12), 1-15. [More Information]
Bos, J., Hebl, V., Oberg, A., Sun, Z., Herman, D., Teekakirikul, P., Seidman, J., Seidman, C., dos Remedios, C., Maleszewski, J., et al (2020). Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2–Mediated COVID-19. Mayo Clinic Proceedings, 95(7), 1354-1368. [More Information]
Herwig, M., Kolijn, D., Lódi, M., Hölper, S., Kovács, Á., Papp, Z., Jaquet, K., Haldenwang, P., Dos Remedios, C., Reusch, P., et al (2020). Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D. Frontiers in Physiology, 11, 1-23. [More Information]
Pandzic, E., Morkel, C., Li, A., Cooke, R., Whan, R., dos Remedios, C. (2020). Nanomolar ATP binding to single myosin cross-bridges in rigor: a molecular approach to studying myosin ATP kinetics using single human cardiomyocytes. Biophysical Reviews, 12(4), 1031-1040. [More Information]
Ashna, A., van Helden, D., Dos Remedios, C., Molenaar, P., Laver, D. (2020). Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action. Molecular Pharmacology, 97(4), 250-258. [More Information]
Brayson, D., Holohan, S., Bardswell, S., Arno, M., Lu, H., Jensen, H., Tran, P., Barallobre-Barreiro, J., Mayr, M., Dos Remedios, C., et al (2020). Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement. Journal of the American Heart Association, 9(16), e015342. [More Information]
Nijenkamp, L., Bollen, I., Niessen, H., Dos Remedios, C., Michels, M., Poggesi, C., Ho, C., Kuster, D., van der Velden, J. (2020). Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy. PloS One, 15(5), e0232427. [More Information]

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2019

Li, A., Lal, S., Dos Remedios, C. (2019). A step towards understanding the molecular nature of human heart failure: advances using the Sydney Heart Bank collection. Biophysical Reviews, 11(2), 241-244. [More Information]
Walweel, K., Gomez-Hurtado, N., Rebbeck, R., Oo, Y., Beard, N., Molenaar, P., Dos Remedios, C., van Helden, D., Cornea, R., Knollmann, B., et al (2019). Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814. Journal of Molecular and Cellular Cardiology, 130, 96-106. [More Information]
Liu, C., Lim, S., Teo, M., Tan, M., Kulkarni, M., Qiu, B., Li, A., Lal, S., Dos Remedios, C., Tan, N., et al (2019). Collaborative Regulation of LRG1 by TGF-Beta1 and PPAR-Beta/Delta Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis. Circulation. Heart Failure, 12(12), 1-16. [More Information]
Le, T., Pickett, H., Yang, A., Ho, J., Thavapalachandran, S., Igoor, S., Yang, S., Farraha, M., Voges, H., Hudson, J., Dos Remedios, C., Bryan, T., Kizana, E., Chong, J. (2019). Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells. Scientific Reports, 9(1), 1-17. [More Information]
Dos Remedios, C. (2019). Letter from the Editor. Biophysical Reviews, 11(2), 127-128. [More Information]
Ge, Z., Li, A., McNamara, J., Dos Remedios, C., Lal, S. (2019). Pathogenesis and pathophysiology of heart failure with reduced ejection fraction: translation to human studies. Heart Failure Reviews, 24(5), 743-758. [More Information]
Dos Remedios, C., Marrocco, V., Bogomolovas, J., Ehler, E., Yu, J., Gao, C., Lange, S. (2019). PKC and PKN in heart disease. Journal of Molecular and Cellular Cardiology, 128, 212-226. [More Information]
Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M., Hayward, R., Ahmad, S., Vizcay-Barrena, G., Protti, A., Zammit, P., Dos Remedios, C., et al (2019). Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies. JCI Insight, 4(22), 1-19. [More Information]
Dorsch, L., Schuldt, M., Dos Remedios, C., Schinkel, A., de Jong, P., Michels, M., Kuster, D., Brundel, B., van der Velden, J. (2019). Protein quality control activation and microtubule remodeling in hypertrophic cardiomyopathy. Cells, 8(7). [More Information]
Dos Remedios, C. (2019). Recollections of 50 years of research in biophysics: a matter of hard work and luck. Biophysical Reviews, 11(2), 135-137. [More Information]
Piroddi, N., Witjas-Paalberends, E., Ferrara, C., Ferrantini, C., Vitale, G., Scellini, B., Wijnker, P., Sequiera, V., Dooijes, D., Dos Remedios, C., et al (2019). The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM. Journal of General Physiology, 151(1), 18-29. [More Information]
van Heesch, S., Witte, F., Schneider-Lunitz, V., Schulz, J., Adami, E., Faber, A., Kirchner, M., Maatz, H., Blachut, S., Sandmann, C., Dos Remedios, C., et al (2019). The Translational Landscape of the Human Heart. Cell, 178(1), 242-260.e29. [More Information]
Grund, A., Szaroszyk, M., Korf-Klingebiel, M., Malek Mohammadi, M., Trogisch, F., Schrameck, U., Gigina, A., Tiedje, C., Gaestel, M., Kraft, T., Dos Remedios, C., et al (2019). TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation. EMBO Molecular Medicine, 11(10), e10018. [More Information]

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2018

Kanellis, V., Dos Remedios, C. (2018). A review of heavy metal cation binding to deoxyribonucleic acids for the creation of chemical sensors. Biophysical Reviews, 10(5), 1401-1414. [More Information]
Gotzmann, M., Grabbe, S., Schone, D., von Frieling-Salewsky, M., Dos Remedios, C., Strauch, J., Bechtel, M., Dietrich, J., Tannapfel, A., Mugge, A., et al (2018). Alterations in Titin Properties and Myocardial Fibrosis Correlate With Clinical Phenotypes in Hemodynamic Subgroups of Severe Aortic Stenosis. JACC: Basic to Translational Science, 3(3), 335-346. [More Information]
Dos Remedios, C. (2018). An historical perspective of the discovery of titin filaments -Part 2. Biophysical Reviews, 10(4), 1201-1203. [More Information]
Montag, J., Kowalski, K., Makul, M., Ernstberger, P., Radocaj, A., Beck, J., Becker, E., Tripathi, S., Keyser, B., Muhlfeld, C., Dos Remedios, C., et al (2018). Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy. Frontiers in Physiology, 9(359), 1-15. [More Information]
da Silva Goncalves, B., van Der Bruggen, C., Kurakula, K., Sun, X., Casali, K., Casali, A., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., et al (2018). Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension. Circulation, 137(9), 910-924. [More Information]
Dos Remedios, C., Lal, S., Li, A., McNamara, J., Keogh, A., MacDonald, P., Cooke, R., Ehler, E., Knoll, R., Marston, S., et al (2018). Correction to: The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease. Biophysical Reviews, 10(3), 941. [More Information]
Iorga, B., Schwanke, K., Weber, N., Wendland, M., Greten, S., Piep, B., Dos Remedios, C., Martin, U., Zweigerdt, R., Kraft, T., et al (2018). Differences in Contractile Function of Myofibrils within Human Embryonic Stem Cell-Derived Cardiomyocytes vs Adult Ventricular Myofibrils Are Related to Distinct Sarcomeric Protein Isoforms. Frontiers in Physiology, 8(1111), 1-20. [More Information]
Dos Remedios, C., Li, A. (2018). Editorial for issue #1 2018. Biophysical Reviews, 10(1), 1-2. [More Information]
Martin-Garrido, A., Biesiadecki, B., Salhi, H., Shaifta, Y., Dos Remedios, C., Ayuz-Guner, S., Cai, W., Ge, Y., Avkiran, M., Kentish, J. (2018). Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis. Journal of Biological Chemistry, 293(22), 8588-8599. [More Information]
Dos Remedios, C., Li, A., Lal, S. (2018). Non-sarcomeric causes of heart failure: a Sydney Heart Bank perspective. Biophysical Reviews, 10(4), 949-954. [More Information]
Coleman, J., Mouat, M., Wu, J., Jancovski, N., Bassi, J., Chan, A., Humphreys, D., Mrad, N., Yu, Z., Ngo, T., Dos Remedios, C., et al (2018). Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control. Biology of Sex Differences, 9(1), 1-13. [More Information]
Le, T., Pickett, H., Dos Remedios, C., Barbaro, P., Kizana, E., Chong, J. (2018). Platelet-Derived Growth Factor Receptor-Alpha expressing cardiac progenitor cells can be derived from previously cryopreserved human heart samples. Stem Cells and Development, 27(3), 184-198. [More Information]
Krysiak, J., Unger, A., Beckendorf, L., Hamdani, N., von Frieling-Salewsky, M., Redfield, M., Dos Remedios, C., Sheikh, F., Gergs, U., Boknik, P., et al (2018). Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes. Nature Communications, 9(1), 1-14. [More Information]
Coats, C., Heywood, W., Virasami, A., Ashrafi, N., Syrris, P., Dos Remedios, C., Treibel, T., Moon, J., Lopes, L., McGregor, C., et al (2018). Proteomic Analysis of the Myocardium in Hypertrophic Obstructive Cardiomyopathy. Circulation. Genomic and Precision Medicine, 11(12), 1-10. [More Information]
Dos Remedios, C. (2018). Reviews arising from the 2017 conference of the Australian Society for Biophysics and the Japanese Society for Biophysics. Biophysical Reviews, 10(5), 1215-1220. [More Information]
Kagemoto, T., Oyama, K., Yamane, M., Tsukamoto, S., Kobirumaki-Shimozawa, F., Li, A., Dos Remedios, C., Fukuda, N., Ishiwata, S. (2018). Sarcomeric Auto-Oscillations in Single Myofibrils From the Heart of Patients With Dilated Cardiomyopathy. Circulation. Heart Failure, 11(7), e004333. [More Information]
Lin, B., Li, A., Mun, J., Previs, M., Previs, S., Campbell, S., Dos Remedios, C., Tombe, P., Craig, R., Warshaw, D., et al (2018). Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner. Scientific Reports, 8(1), 1-13. [More Information]

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2017

Dos Remedios, C., Peckham, M. (2017). 3Rs and biophysics. Biophysical Reviews, 9(4), 277-278. [More Information]
Land, S., Park-Holohan, S., Smith, N., Dos Remedios, C., Kentish, J., Niederer, S. (2017). A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes. Journal of Molecular and Cellular Cardiology, 106, 68-83. [More Information]
Dos Remedios, C. (2017). A review and summary of the contents of biophysical reviews volume 8, 2016. Biophysical Reviews, 9(1), 1-4. [More Information]
Vikhorev, P., Smoktunowicz, N., Munster, A., Copeland, O., Kostin, S., Montgiraud, C., Messer, A., Toliat, M., Li, A., Dos Remedios, C., Lal, S., et al (2017). Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes. Scientific Reports, 7(1), 1-11. [More Information]
Dos Remedios, C., Gilmour, D. (2017). An historical perspective of the discovery of titin filaments. Biophysical Reviews, 9(3), 179-188. [More Information]
Mamidi, R., Li, J., Gresham, K., Verma, S., Doh, C., Li, A., Lal, S., Dos Remedios, C., Stelzer, J. (2017). Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium. Circulation. Heart Failure, 10(10), 1-11. [More Information]
Crossman, D., Shen, X., Jullig, M., Munro, M., Hou, Y., Middleditch, M., Shrestha, D., Li, A., Lal, S., Dos Remedios, C., et al (2017). Increased collagen within the transverse tubules in human heart failure. Cardiovascular Research, 113(8), 879-891. [More Information]
Montag, J., Syring, M., Rose, J., Weber, A., Ernstberger, P., Mayer, A., Becker, E., Keyser, B., Dos Remedios, C., Perrot, A., et al (2017). Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy. Journal Of Muscle Research And Cell Motility, 38(3-4), 291-302. [More Information]
McNamara, J., Li, A., Lal, S., Bos, J., Harris, S., van der Velden, J., Ackerman, M., Cooke, R., Dos Remedios, C. (2017). MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy. PloS One, 12(6), 1-22. [More Information]
Bollen, I., Ehler, E., Fleischanderl, K., Bouwman, F., Kempers, L., Ricke-Hoch, M., Hilfiker-Kleiner, D., Dos Remedios, C., Kruger, M., Vink, A., et al (2017). Myofilament Remodeling and Function Is More Impaired in Peripartum Cardiomyopathy Compared with Dilated Cardiomyopathy and Ischemic Heart Disease. American Journal of Pathology, 187(12), 2645-2658. [More Information]
Heinig, M., Adriaens, M., Schafer, S., van Deutekom, H., Lodder, E., Ware, J., Schneider, V., Felkin, L., Creemers, E., Dos Remedios, C., et al (2017). Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy. Genome Biology, 18(170), 1-21. [More Information]
Dos Remedios, C. (2017). New insights into real-time multiprotein fluorescence microscopy. Biophysical Reviews, 9(2), 65-66. [More Information]
Walweel, K., Molenaar, P., Imtiaz, M., Denniss, A., Dos Remedios, C., van Helden, D., Dulhunty, A., Laver, D., Beard, N. (2017). Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts. Journal of Molecular and Cellular Cardiology, 104, 53-62. [More Information]
Hall, D., Dos Remedios, C. (2017). Special Issue of Biophysical Reviews dedicated to the 19th IUPAB Conference in Edinburgh, Scotland (July 2017). Biophysical Reviews, 9(4), 269-271. [More Information]
Li, A., Dos Remedios, C. (2017). Special issue on titin and its binding proteins in striated muscle. Biophysical Reviews, 9(3), 177-178. [More Information]
Dos Remedios, C., Lal, S., Li, A., McNamara, J., Keogh, A., Macdonald, P., Cooke, R., Ehler, E., Knoll, R., Marston, S., et al (2017). The Sydney Heart Bank: improving translational research while eliminating or reducing the use of animal models of human heart disease. Biophysical Reviews, 9(4), 431-441. [More Information]

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2016

McNamara, J., Li, A., Smith, N., Lal, S., Graham, R., Kooiker, K., van Dijk, S., Dos Remedios, C., Harris, S., Cooke, R. (2016). Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes. Journal of Molecular and Cellular Cardiology, 94, 65-71. [More Information]
Lin, Z., Guo, H., Cao, Y., Zohrabian, S., Zhou, P., Ma, Q., Vandusen, N., Guo, Y., Zhang, J., Li, A., Dos Remedios, C., et al (2016). Acetylation of VGLL4 Regulates Hippo-YAP Signaling and postnatal cardiac growth. Developmental Cell, 39(4), 466-479. [More Information]
Dos Remedios, C. (2016). Biophysical Reviews publications on DNA structure and function that complement this Special Issue on DNA supercoiling. Biophysical Reviews, 8(Suppl 1), 157-158. [More Information]
Dyer, W., Tan, J., Day, T., Kiers, L., Kiernan, M., Yiannikas, C., Reddel, S., Ng, K., Mondy, P., Dennington, P., Dos Remedios, C., Vucic, S., et al (2016). Immunomodulation of inflammatory leukocyte markers during intravenous immunoglobulin treatment associated with clinical efficacy in chronic inflammatory demyelinating polyradiculoneuropathy. Brain and Behavior, 6(10), 1-11. [More Information]
Lal, S., Li, A., Dos Remedios, C. (2016). Limitations in Translating Animal Studies to Humans in Cardiovascular Disease. Journal of Cardiovascular Translational Research, 9(2), 165-166. [More Information]
Huang, Z., Ding, Y., Chen, J., Wu, G., Kataoka, M., Hu, Y., Yang, J., Liu, J., Drakos, S., Dos Remedios, C., et al (2016). Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy. Cardiovascular Research, 112(2), 543-554. [More Information]
Lange, S., Gehmlich, K., Lun, A., Blondelle, J., Hooper, C., Dalton, N., Alvarez, E., Zhang, X., Bang, M., Abassi, Y., Dos Remedios, C., et al (2016). MLP and CARP are linked to chronic PKC(alpha) signalling in dilated cardiomyopathy. Nature Communications, 7, 1-11. [More Information]
Messer, A., Bayliss, C., El-Mezgueldi, M., Redwood, C., Ward, D., Leung, M., Papadaki, M., Dos Remedios, C., Marston, S. (2016). Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca2+-sensitivity and suppress the modulation of Ca2+-sensitivity by troponin I phosphorylation. Archives of Biochemistry and Biophysics, 601, 113-120. [More Information]
Dos Remedios, C. (2016). On life after Proteomics. Proteomics, 16(22), 2839-2839. [More Information]
Dos Remedios, C. (2016). The evolution of Biophysical Reviews. Biophysical Reviews, 8(1), 1-3. [More Information]
Dos Remedios, C. (2016). This issue of Biophysical Reviews is a little different. Biophysical Reviews, 8(2), 85-86. [More Information]
Lal, S., Nguyen, L., Tezone, R., Ponten, F., Odeberg, J., Li, A., Dos Remedios, C. (2016). Tissue microarray profiling in human heart failure. Proteomics, 16(17), 2319-2326. [More Information]

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2015

Wijnker, P., Li, Y., Zhang, P., Foster, B., Dos Remedios, C., van Eyk, J., Stienen, G., Murphy, A., van der Velden, J. (2015). A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis. Journal of Molecular and Cellular Cardiology, 82, 93-103. [More Information]
Pluess, M., Daeubler, G., Dos Remedios, C., Ehler, E. (2015). Adaptations of cytoarchitecture in human dilated cardiomyopathy. Biophysical Reviews, 7, 25-32. [More Information]
Sequeira, V., Najafi, A., Wijnker, P., Dos Remedios, C., Michels, M., Kuster, D., van der Velden, J. (2015). ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease. Proceedings of the National Academy of Sciences of the United States of America, 112(50), e7003-e7012. [More Information]
Lal, S., Li, A., Allen, D., Allen, P., Bannon, P., Cartmill, T., Cooke, R., Farnswoirth, A., Keogh, A., Dos Remedios, C. (2015). Best practice BioBanking of human heart tissue. Biophysical Reviews, 7(4), 399-406. [More Information]
Foster, S., Porrello, E., Stefani, M., Smith, N., Molenaar, P., Dos Remedios, C., Thomas, W., Ramialison, M. (2015). Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388, 1009-1027. [More Information]
Ge, Z., Lal, S., Le, T., Dos Remedios, C., Chong, J. (2015). Cardiac stem cells: translation to human studies. Biophysical Reviews, 7(1), 127-139. [More Information]
Bergmann, O., Zdunek, S., Felker, A., Salehpour, M., Alkass, K., Bernard, S., Sjostrom, S., Szewczykowska, M., Jackowska, T., Dos Remedios, C., et al (2015). Dynamics of Cell Generation and Turnover in the Human Heart. Cell, 161(7), 1566-1575. [More Information]
Mamidi, R., Gresham, K., Li, A., Dos Remedios, C., Stelzer, J. (2015). Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C. Journal of Molecular and Cellular Cardiology, 85, 262-272. [More Information]
Polizzotti, B., Ganapathy, B., Walsh, S., Choudhury, S., Ammanamanchi, N., Bennett, D., Dos Remedios, C., Haubner, B., Penninger, J., Kuhn, B. (2015). Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window. Science Translational Medicine, 7(281), 1-13. [More Information]
Chahine, M., Mioulane, M., Sikkel, M., Oâ€™Gara, P., Dos Remedios, C., Pierce, G., Lyon, A., Foldes, G., Harding, S. (2015). Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts. Cardiovascular Research, 105(1), 31-43. [More Information]
Marston, S., Montgiraud, C., Munster, A., Copeland, O., Choi, O., Dos Remedios, C., Messer, A., Ehler, E., KnÃ¶ll, R. (2015). OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency. PloS One, 10(9), 1-10. [More Information]
Lynch, T., Sivaguru, M., Velayutham, M., Cardounel, A., Michels, M., Barefield, D., Govindan, S., Dos Remedios, C., van der Velden, J., Sadayappan, S. (2015). Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation. Oxidative Medicine and Cellular Longevity, 2015, 1-14. [More Information]
Li, A., Dos Remedios, C. (2015). Special Issue on human heart failure. Biophysical Reviews, 7(1), 1-3. [More Information]
Kagemoto, T., Li, A., Dos Remedios, C., Ishiwata, S. (2015). Spontaneous oscillatory contraction (SPOC) in cardiomyocytes. Biophysical Reviews, 7(1), 15-24. [More Information]
Sequeira, V., Najafi, A., Mcconnell, M., Fowler, E., Bollen, I., Wust, R., Dos Remedios, C., Helmes, M., White, E., Stienen, G., et al (2015). Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness. Journal of Physiology, 593(17), 3899-3916. [More Information]
McNamara, J., Li, A., Dos Remedios, C., Cooke, R. (2015). The role of super-relaxed myosin in skeletal and cardiac muscle. Biophysical Reviews, 7(1), 5-14. [More Information]

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2014

Kosobrodova, E., Mohamed, A., Su, Y., Kondyurin, A., Dos Remedios, C., McKenzie, D., Bilek, M. (2014). Cluster of differentiation antibody microarrays on plasma immersion ion implanted polycarbonate. Materials Science and Engineering C, 35(1), 434-440. [More Information]
Manders, E., Bogaard, H., Handoko, L., Van De Veerdonk, M., Keogh, A., Westerhof, N., Stienen, G., Dos Remedios, C., Humbert, M., Dorfmuller, P., et al (2014). Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension. Journal of the American College of Cardiology, 64(1), 28-37. [More Information]
Marsman, R., Bezzina, C., Freiberg, F., Verkerk, A., Adriaens, M., Podliesna, S., Chen, C., PurfÃ¼rst, B., Spallek, B., Koopmann, T., Dos Remedios, C., et al (2014). Coxsackie and Adenovirus Receptor is a Modifier of Cardiac Conduction and Arrhythmia Vulnerability in the Setting of Myocardial Ischemia. Journal of the American College of Cardiology, 63(6), 549-559. [More Information]
Walweel, K., Li, J., Molenaar, P., Imtiaz, M., Quail, A., Dos Remedios, C., Beard, N., Dulhunty, A., van Helden, D., Laver, D. (2014). Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum. Journal of General Physiology, 144(3), 263-271. [More Information]
Witjas-Paalberends, E., Gulcu, A., Germans, T., Knaapen, P., Harms, H., Vermeer, A., Christiaans, I., Wilde, A., Dos Remedios, C., Lammertsma, A., et al (2014). Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations. Cardiovascular Research, 103(2), 248-257. [More Information]
Koopmann, T., Adriaens, M., Moerland, P., Marsman, R., Westerveld, M., Lal, S., Zhang, T., Simmons, C., Baczko, I., Dos Remedios, C., et al (2014). Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart. PloS One, 9(5), 1-11. [More Information]
Wijnker, P., Sequeira, V., Foster, D., Li, Y., Dos Remedios, C., Murphy, A., Stienen, G., van der Velden, J. (2014). Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation. American Journal of Physiology - Heart and Circulatory Physiology, 306(8), H1171-H1181. [More Information]
Wijnker, P., Sequeira, V., Witjas-Paalberends, E., Foster, D., Dos Remedios, C., Murphy, A., Stienen, G., van der Velden, J. (2014). Phosphorylation of protein kinase C sites Ser42/44 decreases Ca 2+-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes. Archives of Biochemistry and Biophysics, 15(554), 11-21. [More Information]
Van Dijk, S., Boontje, N., Heymans, M., ten Cate, F., Michels, M., Dos Remedios, C., Dooijes, D., van Slegtenhorst, M., van der Velden, J., Stienen, G. (2014). Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations. Pfluegers Archiv: European Journal of Physiology, 466(8), 1619-2633. [More Information]
Rain, S., da Silva Goncalves Bos, D., Handoko, L., Westerhof, N., Stienen, G., Ottenheijm, C., Goebel, M., Dorfmuller, P., Guignabert, C., Humbert, M., Dos Remedios, C., et al (2014). Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension. Journal of the American Heart Association, 3(3), 1-11. [More Information]
Saba, A., Donzelli, R., Colligiani, D., Raffaelli, A., Nannipieri, M., Kusmic, C., Dos Remedios, C., Simonides, W., Lervasi, G., Zucchi, R. (2014). Quantification of thyroxine and 3,5,3'-triiodo-thyronine in human and animal hearts by a novel liquid chromatography-tandem mass spectrometry method. Hormone And Metabolic Research, 46(9), 628-634. [More Information]
Dwyer, J., Pluess, M., Iskratsch, T., Dos Remedios, C., Ehler, E. (2014). The Formin FHOD1 in Cardiomyocytes. The Anatomical Record, 297(9), 1560-1570. [More Information]

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2013

Lin, M., Ho, J., Harrison, L., Dos Remedios, C., Adelstein, S. (2013). An antibody-based leukocyte-capture microarray for the diagnosis of systemic lupus erythematosus. PloS One, 8(3), 1-8. [More Information]
Mollova, M., Bersell, K., Walsh, S., Savla, J., Das, L., Park, S., Silberstein, L., Dos Remedios, C., Graham, D., Colan, S., et al (2013). Cardiomyocyte proliferation contributes to heart growth in young humans. Proceedings of the National Academy of Sciences of the United States of America, 110(4), 1446-1451. [More Information]
Hamdani, N., Krysiak, J., Kreusser, M., Neef, S., Dos Remedios, C., Maier, L., KrÃ¼ger, M., Backs, J., Linke, W. (2013). Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circulation Research, 112(4), 664-674. [More Information]
Velonas, V., Woo, H., Dos Remedios, C., Assinder, S. (2013). Current Status of Biomarkers for Prostate Cancer. International Journal of Molecular Sciences, 14(6), 11034-11060. [More Information]
Kotter, S., Gout, L., Von Frieling-Salewsky, M., Muller, A., Helling, S., Marcus, K., Dos Remedios, C., Linke, W., Kruger, M. (2013). Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts. Cardiovascular Research, 99(4), 648-656. [More Information]
Memo, M., Leung, M., Ward, D., Dos Remedios, C., Morimoto, S., Zhang, L., Ravenscroft, G., McNamara, E., Nowak, K., Marston, S., et al (2013). Familial dilated cardiomyopathy mutations uncouple troponin l phosphorylation from changes in myofibrillar Ca2+ sensitivity. Cardiovascular Research, 99(1), 65-73. [More Information]
Hall, D., Dos Remedios, C. (2013). Foreword to the biophysics of protein-protein and protein-ligand interactions in dilute and crowded media - a special issue in honor of Allen Minton's 70th birthday. Biophysical Reviews, 5(2), 57-60. [More Information]
Cordell, H., Bentham, J., Topf, A., Zelenika, D., Heath, S., Mamasoula, C., Cosgrove, C., Blue, G., Granados-Riveron, J., Setchfield, K., Dos Remedios, C., Winlaw, D., et al (2013). Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. Nature Genetics, 45(7), 822-824. [More Information]
Kuster, D., Sequeira, V., Najafi, A., Boontje, N., Wijnker, P., Paalberends, R., Marston, S., Dos Remedios, C., Carrier, L., Demmers, J., et al (2013). GSK3Î² phosphorylates newly identified site in the proline-alanine-rich region of cardiac myosin-binding protein C and alters cross-bridge cycling kinetics in human: Short communication. Circulation Research, 112(4), 633-639. [More Information]
Li, A., Estigoy, C., Raftery, M., Cameron, D., Odeberg, J., Ponten, F., Lal, S., Dos Remedios, C. (2013). Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank. Heart, Lung, and Circulation, 22(10), 819-826. [More Information]
Wijnker, P., Foster, D., Tsao, A., Frazier, A., Dos Remedios, C., Murphy, A., Stienen, G., van der Velden, J. (2013). Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes. American Journal of Physiology - Heart and Circulatory Physiology, 304(2), H260-H268. [More Information]
Hirsh, S., Bilek, M., Bax, D., Kondyurin, A., Kosobrodova, E., Tsoutas, K., Tran, C., Waterhouse, A., Yin, Y., Nosworthy, N., McKenzie, D., Dos Remedios, C., Weiss, A., et al (2013). Ion Implanted, Radical-Rich Surfaces For The Rapid Covalent Immobilization Of Active Biomolecules. AIP Conference Proceedings, 1525, 364-369. [More Information]
Kuster, D., Mulders, J., ten Cate, F., Michels, M., Dos Remedios, C., da Costa Martins, P., van der Velden, J., Oudejans, C. (2013). MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. Journal of Molecular and Cellular Cardiology, 65, 59-66. [More Information]
Witjas-Paalberends, E., Piroddi, N., Stam, K., Van Dijk, S., Sequeira Oliviera, V., Ferrara, C., Scellini, B., Hazebroek, M., ten Cate, F., van Slegtenhorst, M., Dos Remedios, C., et al (2013). Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy. Cardiovascular Research, 99, 432-441. [More Information]
Bayliss, C., Jacques, A., Leung, M., Ward, D., Redwood, C., Gallon, C., Copeland, O., McKenna, W., Dos Remedios, C., Marston, S., et al (2013). Myofibrillar Ca(2+) sensitivity is uncoupled from troponin l phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. Cardiovascular Research, 97(3), 500-508. [More Information]
Sequeira, V., Wijnker, P., Nijenkamp, L., Kuster, D., Najafi, A., Witjas-Paalberends, E., Regan, J., Boontje, N., Ten Cate, F., Germans, T., Dos Remedios, C., et al (2013). Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. Circulation Research, 112(11), 1491-1505. [More Information]
Kooij, V., Zhang, P., Piersma, S., Sequeira, V., Boontje, N., Wijnker, P., Jimenez, C., Jaquet, K., Dos Remedios, C., Murphy, A., et al (2013). PKCÎ±-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis. PloS One, 8(10), 1-10. [More Information]
Rain, S., Handoko, L., Trip, P., Gan, T., Westerhof, N., Stienen, G., Paulus, W., Ottenheijm, C., Marcus, T., Dorfmuller, P., Dos Remedios, C., et al (2013). Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension. Circulation, 128(18), 2016-2025. [More Information]

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2012

Wiggers, W., Olson, W., Dos Remedios, C. (2012). Computational opportunities for remote collaboration and capacity building afforded by Web 2.0 and cloud computing. Biophysical Reviews, 4(3), 153-160. [More Information]
van Dijk, S., Paalberends, R., Najafi, A., Michels, M., Sadayappan, S., Carrier, L., Boontje, N., Kuster, D., van Slegtenhorst, M., Dooijes, D., Dos Remedios, C., et al (2012). Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function. Circulation. Heart Failure, 5(1), 36-46. [More Information]
Dos Remedios, C., Nakamura, H. (2012). Editorial. Biophysical Reviews, 4(3), 149-151. [More Information]
Ling, L., Khammy, O., Byrne, M., Amirahmadi, F., Foster, A., Li, G., Zhang, L., Dos Remedios, C., Chen, C., Kaye, D. (2012). Irregular rhythm adversely influences calcium handling in ventricular myocardium. Circulation. Heart Failure, 5(6), 786-793. [More Information]
Zhang, P., Kirk, J., Ji, W., Dos Remedios, C., Kass, D., van Eyk, J., Murphy, A. (2012). Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart. Circulation, 126(15), 1828-1837. [More Information]
Li, A., Ponten, F., Dos Remedios, C. (2012). The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development. Proteomics, 12(2), 203-225. [More Information]

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2011

Polden, J., McManus, C., Dos Remedios, C., Dunn, M. (2011). A 2-D gel reference map of the basic human heart proteome. Proteomics, 11(17), 3582-3586. [More Information]
Foreman, A., Phillips, L., Kanellis, V., Hammoudeh, D., Naumann, C., Wong, H., Chisari, R., Hibbert, D., Lee, G., Patra, R., Dos Remedios, C., et al (2011). A DNA-based assay for toxic chemicals in wastewater. Environmental Toxicology and Chemistry, 30(8), 1810-1818. [More Information]
Morales, M., Dos Remedios, C. (2011). Biophysical educational experiment: science and goodwill in Latin America and Africa. Biophysical Reviews, 3, 101-106. [More Information]
Bilek, M., Bax, D., Kondyurin, A., Yin, Y., Nosworthy, N., Fisher, K., Waterhouse, A., Weiss, A., Dos Remedios, C., McKenzie, D. (2011). Free radical functionalization of surfaces to prevent adverse responses to biomedical devices. Proceedings of the National Academy of Sciences of the United States of America, 108(35), 14405-14410. [More Information]
Hirsh, S., Nosworthy, N., Kondyurin, A., Dos Remedios, C., McKenzie, D., Bilek, M. (2011). Linker-free covalent thermophilic b-glucosidase functionalized polymeric surfaces. Journal of Materials Chemistry, 21, 17832-17841. [More Information]
Maeder, M., Khammy, O., Dos Remedios, C., Kaye, D. (2011). Myocardial and Systemic Iron Depletion in Heart Failure: Implications for Anemia Accompanying Heart Failure. Journal of the American College of Cardiology, 58(5), 474-480. [More Information]
Wijnker, P., Boknik, P., Gergs, U., Muller, F., Neumann, J., Dos Remedios, C., Schmitz, W., Sindermann, J., Stienen, G., van der Velden, J., et al (2011). Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium. Journal Of Muscle Research And Cell Motility, 32(3), 221-233. [More Information]
Wolfe, J., Ishiwata, S., Braet, F., Whan, R., Su, Y., Lal, S., Dos Remedios, C. (2011). SPontaneous Oscillatory Contraction (SPOC): auto-oscillations observed in striated muscle at partial activation. Biophysical Reviews, 3(2), 53-62. [More Information]
Changsirivathanathamrong, D., Wang, Y., Rajbhandari, D., Maghzal, G., Mak, W., Woolfe, C., Duflou, J., Gebski, V., Dos Remedios, C., Celermajer, D., Stocker, R. (2011). Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. Critical Care Medicine, 39(12), 2678-2683. [More Information]

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2010

Hirsh, S., Bilek, M., Nosworthy, N., Kondyurin, A., Dos Remedios, C., McKenzie, D. (2010). A Comparison of Covalent Immobilization and Physical Adsorption of a Cellulase Enzyme Mixture. Langmuir, 26(17), 14380-14388. [More Information]
Ho, J., Lin, M., Adelstein, S., Dos Remedios, C. (2010). Customising an antibody leukocyte capture microarray for systemic lupus erythematosus: Beyond biomarker discovery. Proteomics - Clinical Applications, 4(2), 179-189. [More Information]
Kooij, V., Saes, M., Jaquet, K., Zaremba, R., Foster, D., Murphy, A., Dos Remedios, C., van der Velden, J., Stienen, G. (2010). Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background. Journal of Molecular and Cellular Cardiology, 48(5), 954-963. [More Information]
Iskratsch, T., Lange, S., Dwyer, J., Kho, A., Dos Remedios, C., Ehler, E. (2010). Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance. The Journal of Cell Biology, 191(6), 1159-1172. [More Information]
Kong, S., Hu, Y., Ho, J., Ikeda, S., Polster, S., John, R., Hall, J., Bisping, E., Pieske, B., Dos Remedios, C., et al (2010). Heart Failure-Associated Changes in RNA Splicing of Sarcomere Genes. Circulation: Cardiovascular Genetics, 3(2), 138-146. [More Information]
Mohamed, A., Lal, S., Ho, J., Brown, A., Lui, R., Nguyen, L., Yong, A., Su, Y., Braet, F., Dyer, W., Junius, F., Cumming, R., Freedman, B., Kritharides, L., Dos Remedios, C. (2010). How to interrogate the cellular immune system in patients with ischemic heart disease. In Dmitry Vukovic & Vladimir Kiyan (Eds.), Myocardial ischemia: Causes, symptoms and treatment, (pp. 195-216). United States: Nova Science Publishers.
Kwok, D., Tong, L., Yeung, C., Dos Remedios, C., Chu, P. (2010). Hybrid plasma surface modification and ion implantation of biopolymers. Surface & Coatings Technology, 204(18-19), 2892-2897. [More Information]
Lal, S., Dos Remedios, C. (2010). Is There a Connection between Ablation of Atrial Fibrillation and Reduced Apoptosis? Cardiology, 117(3), 161-2. [More Information]
Hamdani, N., Borbely, A., Veenstra, S., Kooij, V., Vrydag, W., Zaremba, R., Dos Remedios, C., Niessen, H., Michel, M., Paulus, W., et al (2010). More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease. Journal Of Muscle Research And Cell Motility, 31(4), 289-301. [More Information]
Hoskins, A., Jacques, A., Bardswell, S., McKenna, W., Tsang, V., Dos Remedios, C., Ehler, E., Adams, K., Jalilzadeh, S., Avkiran, M., et al (2010). Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 49(5), 737-745. [More Information]
Lu, Z., Xu, X., Hu, X., Lee, S., Traverse, J., Zhu, G., Fassett, J., Tao, Y., Zhang, P., Dos Remedios, C., et al (2010). Oxidative stress regulates left ventricular PDE5 expression in the failing heart. Circulation, 121(13), 1474-1483. [More Information]
Robinson, A., Dunn, M., McCormack, A., Dos Remedios, C., Rose, M. (2010). Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization. Journal of Molecular and Cellular Cardiology, 49(3), 370-379. [More Information]
Kooij, V., Boontje, N., Zaremba, R., Jaquet, K., Dos Remedios, C., Stienen, G., van der Velden, J. (2010). Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca(2+) sensitivity in human myocardium. Basic Research in Cardiology, 105(2), 289-300. [More Information]

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2009

Ho, J., Stefani, M., Dos Remedios, C., Charleston, M. (2009). A model selection approach to discover age-dependent gene expression patterns using quantile regression models. BMC Genomics, 10(Suppl 3), S16-1-S16-18. [More Information]
van Dijk, S., Holewijn, R., Tebeest, A., Dos Remedios, C., Stienen, G., van der Velden, J. (2009). A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients. Journal Of Muscle Research And Cell Motility, 30(7-Aug), 299-302. [More Information]
Van Dijk, S., Dooijes, D., Dos Remedios, C., Michels, M., Lamers, J., Winegrad, S., Schlossarek, S., Carrier, L., ten Cate, F., Stienen, G., et al (2009). Cardiac myosin-binding protein C mutations and hypertrophic ardiomyopathy haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction. Circulation, 119(11), 1473-1483. [More Information]
Estigoy, C., Ponten, F., Odeberg, J., Herbert, B., Guilhaus, M., Charleston, M., Ho, J., Cameron, D., Dos Remedios, C. (2009). Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts. Biophysical Reviews, 1(1), 43-49. [More Information]
Kruger, M., Kotter, S., Grutzner, A., Lang, P., Andresen, C., Redfield, M., Butt, E., Dos Remedios, C., Linke, W. (2009). Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs. Circulation Research, 104(1), 87-94. [More Information]
Dos Remedios, C., Yamane, M., Hughes, J., Stefani, M., Fukuda, N., Kurihara, S., Steenman, M., Ishiwata, S. (2009). SPOC: A Functional Assay of Failing and Non-Failing Human Cardiomyocytes. Biophysical Journal, 96(3 Suppl 1), 224a.
Dos Remedios, C., Yamane, M., Robinson, J., Hughes, J., Stefani, M., Fukuda, N., Kurihara, S., Steenman, M., Ishiwata, S. (2009). Spontaneous Oscillatory Contraction: A Functional Assay of Contractile Function of Human Heart Samples Stored at -190 ÂºC. Heart, Lung, and Circulation, 18(3), S311-S311.
Messer, A., Gallon, C., McKenna, W., Dos Remedios, C., Marston, S. (2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. Proteomics - Clinical Applications, 3, 1371-1382. [More Information]
Lal, S., Brown, A., Nguyen, L., Braet, F., Dyer, W., Dos Remedios, C. (2009). Using antibody arrays to detect microparticles from acute coronary syndrome patients based on Cluster of Differentiation (CD) antigen expression. Molecular and Cellular Proteomics, 8(4), 799-804. [More Information]

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2008

Stefani, M., Tsubakihara, M., Hambly, B., Liew, C., Allen, P., Macdonald, P., Dos Remedios, C. (2008). Actin and its binding proteins in heart failure. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 318-334). New York: Springer Science+Business Media. [More Information]
Dos Remedios, C., Chhabra, D. (2008). Actin-Binding Proteins and Disease. New York: Springer Science+Business Media.
Chhabra, D., Dos Remedios, C. (2008). Actin: an overview of its structure and function. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 1-16). New York: Springer Science+Business Media.
Martinez-Neira, R., Dos Remedios, C., Mackay, I. (2008). An actin-myosin functional assay for analysis of smooth muscle (anti-microfilament) autoantibodies in human plasma. Journal of Immunological Methods, 338(1-2), 63-66. [More Information]
Ho, J., Stefani, M., Dos Remedios, C., Charleston, M. (2008). Differential variability analysis of gene expression and its application to human diseases. Bioinformatics, 24(13), i390-i398. [More Information]
Ho, J., Koundinya, R., Caetano, T., Dos Remedios, C., Charleston, M. (2008). Inferring differential leukocyte activity from antibody microarrays using a latent variable model. Genome Informatics, 21(1), 126-137. [More Information]
Hamdani, N., Waard, M., Messer, A., Boontje, N., Kooij, V., van Dijk, S., Versteilen, A., Lamberts, R., Merkus, D., Dos Remedios, C., et al (2008). Myofilament dysfunction in cardiac disease from mice to men. Journal Of Muscle Research And Cell Motility, 29(6-Aug), 189-201. [More Information]
Hamdani, N., Kooij, V., van Dijk, S., Merkus, D., Paulus, W., Dos Remedios, C., Duncker, D., Stienen, G., van der Velden, J. (2008). Sarcomeric dysfunction in heart failure. Cardiovascular Research, 77(4), 649-658. [More Information]
Fermin, D., Barac, A., Lee, S., Polster, S., Hannenhalli, S., Bergemann, T., Grindle, S., Dyke, D., Pagani, F., Dos Remedios, C., et al (2008). Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure. Circulation: Cardiovascular Genetics, 1(2), 117-125. [More Information]
Brown, A., Lattimore, J., McGrady, M., Sullivan, D., Dyer, W., Braet, F., Dos Remedios, C. (2008). Stable and unstable angina: Identifying novel markers on circulating leukocytes. Proteomics - Clinical Applications, 2, 90-98. [More Information]
Dos Remedios, C., Nosworthy, N. (2008). The role of PIP2 in actin, actin-binding proteins and disease. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. 290-297). New York: Springer Science+Business Media.
Lui, R., Brown, A., Wu, B., Lin, M., Thompson, J., Braet, F., Dyer, W., Lattimore, J., Macdonald, P., Adelstein, S., Dos Remedios, C. (2008). Use of Antibody Microarrays in the Analysis of Inflammation, Autoimmunity, Viral Infection, and Cancer Metastases. In J. E. Van Eyk and M. J. Dunn (Eds.), Clinical Proteomics: From Diagnosis to Therapy, (pp. 571-592). Weinheim: Wiley - V C H Verlag GmbH & Co. KGaA. [More Information]

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2007

Dos Remedios, C., Chhabra, D. (2007). Foreword. In C. dos Remedios and D. Chhabra (Eds.), Actin-Binding Proteins and Disease, (pp. v-vii). New York: Springer Science+Business Media.
Dos Remedios, C. (2007). New and Notable: The regulation of muscle contraction: As in life, it keeps getting more complex. Biophysical Journal, 93(12), 4097-8. [More Information]
Gan, B., Nosworthy, N., McKenzie, D., Dos Remedios, C., Bilek, M. (2007). Plasma immersion ion implantation treatment of polyethylene for enhanced binding of active horseradish peroxidase. Journal of Biomedical Materials Research A, 85A(3), 605-610. [More Information]
Ho, J., Nosworthy, N., Bilek, M., Gan, B., McKenzie, D., Chu, P., Dos Remedios, C. (2007). Plasma-treated polyethylene surfaces for improved binding of active protein. Plasma Processes and Polymers, 4(5), 583-590. [More Information]
Zhang, L., Merkus, D., Hamdani, N., Lamers, J., Paulus, W., Dos Remedios, C., Duncker, D., Stienen, G., van der Velden, J. (2007). Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies. Proteomics - Clinical Applications, 1, 1285-1290. [More Information]
Nicolau, D., Solana, G., Kekic, M., Fulga, F., Mahanivong, C., Wright, S., Dos Remedios, C. (2007). Surface Hydrophobicity modulates the operation of actomyosin-based dynamic nanodevices. Langmuir, 23(21), 10846-10854. [More Information]

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2006

Dos Remedios, C., McKenzie, D., Boswell, R., Lui, R., Bilek, M., Charles, C., Ramdutt, D. (2006). Development of the nanotiter plate for use in antibody and cell array technologies. SPIE - Biomedical Applications of Micro- and Nano-engineering, Australia: SPIE Proceedings.
Narolska, N., Piroddi, N., Belus, A., Boontje, N., Scellini, B., Deppermann, S., Zaremba, R., Musters, R., Dos Remedios, C., Jaquet, K., Murphy, A., et al (2006). Impaired Diastolic Function After Exchange of Endogenous Troponin I with C-Terminal Truncated Troponin I in Human Cardiac Muscle. Circulation Research, 99(9), 1012-1020. [More Information]
Gorbatyuk, V., Nosworthy, N., Robson, S., Bains, N., Maciejewski, M., Dos Remedios, C., King, G. (2006). Mapping the phosphoinositide-binding site on chick cofilin explains how PIP2 regulates the cofilin-actin interaction. Molecular Cell, 24(4), 511-522. [More Information]
Steel, B., McKenzie, D., Bilek, M., Nosworthy, N., Dos Remedios, C. (2006). Nanosecond responses of proteins to ultra-high temperature pulses. Biophysical Journal, 91(6), L66-L68. [More Information]
Dos Remedios, C., Qin, Z., Shi, Y. (2006). The Amazing Human Body:the anatomical display of real human bodies. Australia: Redtail.
Dedova, I., Nikolaeva, O., Safer, D., De La Cruz, E., Dos Remedios, C. (2006). Thymosin beta4 induces a conformational change in actin monomers. Biophysical Journal, 90(3), 985-992. [More Information]

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2005

Martinez-Neira, R., Kekic, M., Nicolau, D., Dos Remedios, C. (2005). A novel biosensor for mercuric ions based on motor proteins. Biosensors and Bioelectronics, 20(7), 1428-1432. [More Information]
Kekic, M., Dos Remedios, C., Martinez, R., Nicolau, D. (2005). An acto/myosin in vitro motility assay as a motion based sensor. Biophysical Society 49th Annual Meeting, Bethesda, MD: Biophysical Society.
Lui, R., Tsubakihara, M., Macdonald, P., Hayward, C., Dos Remedios, C. (2005). Analysing inflammation in heart failure using microarray platforms. 27th Annual Meeting of the American Section of the International Society of Heart Research (ISHR), United Kingdom: Academic Press.
Chhabra, D., Dos Remedios, C. (2005). Cofilin, actin and their complex observed in vivo using fluorescence resonance energy transfer. Biophysical Journal, 89(3), 1902-1908. [More Information]
Thordarson, P., Bilek, M., McKenzie, D., Nosworthy, N., Davies, K., Morrow, R., Gan, B., Dos Remedios, C. (2005). Functional Attachment of Horse Radish Peroxidase to Plasma Treated Surfaces. Smart Materials III, : SPIE Press.
Chhabra, D., Dos Remedios, C. (2005). Intracellular fluorescence resonance energy transfer. Biophysical Journal, 89, 1902-1908.
Jiang, L., Bardini, M., Keogh, A., Dos Remedios, C., Burnstock, G. (2005). P2X1 receptors are closely associated with connexin 43 in human ventricular myocardium. International Journal of Cardiology, 98(2), 291-297. [More Information]
Chhabra, D., Nosworthy, N., Dos Remedios, C. (2005). The N-terminal fragment of gelsolin inhibits the interaction of DNase I with isolated actin, but not with the cofilin-actin complex. Proteomics, 5(12), 3131-3136. [More Information]

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2004

Steel, B., Bilek, M., Dos Remedios, C., McKenzie, D. (2004). Apparatus For Exposing Cell Membranes To Rapid Temperature Transients. European Biophysics Journal, 33(2), 117-120. [More Information]
Tsubakihara, M., Williams, N., Keogh, A., Dos Remedios, C. (2004). Comparison Of Gene Expression Between Left Atria And Left Ventricles From Non-Diseased Humans. Proteomics, 4(1), 261-270. [More Information]
Dedova, I., Dos Remedios, C. (2004). Conformational changes of actin induced by strong or weak myosin subfragment-1 binding. Tsitologiya, 46(8), 719-734. [More Information]
Borovikov, Y., Dedova, I., Dos Remedios, C., Vikhoreva, N., Vikhorev, P., Avrova, S., Hazlett, T., Van Der Meer, B. (2004). Fluorescence Depolarization Of Actin Filaments In Reconstructed Myofibers: The Effect Of S1 Or pPDM-S1 On Movements Of Distinct Areas Of Actin. Biophysical Journal, 86(5), 3020-3029. [More Information]
Lal, S., Lui, R., Nguyen, L., Macdonald, P., Denyer, G., Dos Remedios, C. (2004). Increases In Leukocyte Cluster Of Differentiation Antigen Expression During Cardiopulmonary Bypass In Patients Undergoing Heart Transplantation. Proteomics, 4(7), 1918-1926. [More Information]
Dedova, I., Nikolaeva, O., Mikhailova, V., Dos Remedios, C., Levitsky, D. (2004). Two Opposite Effects Of Cofilin On The Thermal Unfolding Of F-Actin: A Differential Scanning Calorimetric Study. Biophysical Chemistry, 110(1-2), 119-128. [More Information]

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2003

Dos Remedios, C., Chhabra, D., Kekic, M., Dedova, I., Tsubakihara, M., Berry, A., Nosworthy, N. (2003). Actin binding proteins: Regulation of cytoskeletal microfilaments. Physiological Reviews, 83, 433-473. [More Information]
Ng, D., Court, N., Dos Remedios, C., Bogoyevitch, M. (2003). Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts. Cardiovascular Research, 57, 333-346. [More Information]
Dunn, T., Heller, C., McCarthy, S., Dos Remedios, C. (2003). Anatomical study of the "Trochanteric Bursa". Clinical Anatomy, 16(3), 233-240. [More Information]
Steel, B., Bilek, M., Dos Remedios, C., McKenzie, D. (2003). Apparatus for exposing cell membranes to rapid temperature transients. European Biophysics Journal, 11, 117-120. [More Information]
Jiang, L., Huang, Y., Hunyor, S., Dos Remedios, C. (2003). Cardiomyocyte apoptosis is associated with increased wall stress in chronic failing left ventricle. European Heart Journal, 24, 742-751. [More Information]
Dos Remedios, C., Liew, C., Allen, P., Winslow, R., Van Eyk, J., Dunn, M. (2003). Genomics, proteomics and bioinformatics of human heart failure. Journal Of Muscle Research And Cell Motility, 24(4-6), 251-260. [More Information]

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2002

Steel, B., Bilek, M., McKenzie, D., Dos Remedios, C. (2002). A technique for microsecond heating & cooling of a thin (submicron) biological sample. European Biophysics Journal, 31(5), 378-382. [More Information]
Lal, S., Christopherson, R., Dos Remedios, C. (2002). Antibody arrays: an embryonic but rapidly growing technology. Drug Discovery Today, 7(18 Supplement), S143-S149. [More Information]
Court, N., Dos Remedios, C., Cordell, J., Bogoyevitch, M. (2002). Cardiac expression & subcellular localization of the p38 Mitogen-activated protein kinase member, stress-activated protein kinases-3 (SAPK3). Journal of Molecular and Cellular Cardiology, 34(4), 413-426. [More Information]
Dedova, I., Dedov, V., Nosworthy, N., Hambly, B., Dos Remedios, C. (2002). Cofilin and DNase 1 affect the conformation of the small domain of actin. Biophysical Journal, 82, 3134-3143. [More Information]
Heller, C., Marucci, D., Dunn, T., Barr, E., Houang, M., Dos Remedios, C. (2002). Inguinal canal 'Lipoma'. Clinical Anatomy, 15(4), 280-285. [More Information]
Bains, N., Gorbatyuk, V., Nosworthy, N., Robson, S., Maciejewski, M., Dos Remedios, C., King, G. (2002). Letter to the Editor: Backbone and side-chain 1H, 15N, and 13C assignments for chick cofilin. Journal of Biomolecular NMR, 22(2), 193-194.
Mahanivong, C., Wright, J., Kekic, M., Pham, D., Dos Remedios, C., Nicolau, D. (2002). Manipulation of the motility of protein molecular motors on microfabricated substrates. Biomedical Microdevices, 4(2), 111-116. [More Information]
Dos Remedios, C., Thomas, D. (2002). Molecular Interactions of Actin; Actin-Myosin Interaction & Actin-Based Regulation. United States: Springer.
Chhabra, D., Bao, B., Dos Remedios, C. (2002). The distribution of cofilin and DNase I in vivo. Cell Research, 12(3-4), 207-214. [More Information]

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2001

Dos Remedios, C., Thomas, D. (2001). An overview of actin structure and actin-binding proteins. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 1-7). Germany: Springer.
Dos Remedios, C., Moens,, P. (2001). Analysis of models of F-Actin using fluorescence resonance energy transfer spectroscopy. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 59-76). Germany: Springer.
Heinke, M., Yao, M., Chang, D., Einstein, R., Dos Remedios, C. (2001). Apoptosis of ventricular and atrial myocytes from pacing-induced canine heart failure. Cardiovascular Research, 49 (1), 127-134. [More Information]
Jiang, L., Tsubakihara, M., Heinke, M., Phillips, W., Dos Remedios, C., Nosworthy, N., Yao, M. (2001). Heart failure and apoptosis: Electrophoretic methods support data from micro- and macro-arrays. A critical review of genomics and proteomics. Proteomics, 1 (12), 1481-1488.
Belov, L., de la Vega, O., Dos Remedios, C., Christopherson, R., Mulligan,, S. (2001). Immunophenotyping of leukemias using a cluster of differentiation antibody microarray. Cancer Research, 61(11), 4483-4489.
Berry, D., Dos Remedios, C., Keogh, A. (2001). Nuclear membrane proteins in failing human dilated cardiomyopathy. Proteomics, 1 (12), 1507-1512. [More Information]
Kekic, M., Nosworthy, N., Dedova, I., Collyer, C., Dos Remedios, C. (2001). Regulation of the cytoskeleton assembly: a role for a ternary complex of actin with two actin-binding proteins. In Cristobal G. Dos Remedios & David D. Thomas (Eds.), Molecular Interactions of Actin: Actin Structure and Actin-Binding Proteins, (pp. 165-177). Germany: Springer.
Nosworthy, N., Kekic, M., Dos Remedios, C. (2001). The affinity of chick cofilin for actin increases when actin is complexed with DNase 1: Formation of a cofilin-actin-DNase 1 ternary complex. Proteomics, 1 (12), 1513-1518.

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Selected Grants

2017

Developing experimental alternatives to animal models using human heart tissue, Lal S, Li A, Dos Remedios C, Medical Advances Without Animals (MAWA)/Research Grant

2015

The Sydney Human Heart Bank: A resource that eliminates the use of animals in research, Dos Remedios C, King D, Lal S, Li A, Medical Advances Without Animals (MAWA)/Research Grant

2013

CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility, Allbutt H, Ammit A, Assinder S, Bao B, Barrs V, Black J, Brennan-Speranza T, Buckland M, Burgess J, Byrne M, Camp A, Christopherson R, Codd R, Day M, de Graaf S, Dixon K, Dong Q, Dos Remedios C, Fraser S, Fu D, Goldsbury C, Groundwater P, Halliday G, Hambly B, Hardikar A, Hibbs D, Ho P, Hong A, Huang M, Huq F, Jansson P, Johnstone D, Joshua D, Ju Y, Kalinowski D, King N, Kovacevic Z, Kril J, Lai D, Lane D, Lay P, Lee C, Lok H, Lovicu F, Lu Z, Lyons J, Mason R, McLennan S, Morris B, Murphy C, Murray M, Naylor M, Oliver B, Owens T, Poronnik P, Rendina L, Richardson D, Ryan R, Sahni S, Scolyer R, Shafie N, Sharland A, Slobedman B, Sunde M, Sutherland G, Triccas J, Williamson P, Zhu L, Zreiqat H, National Health and Medical Research Council (NHMRC)/Equipment Grant

2012

Wide field super-resolution microscopy with ground state depletion - Exploring nanoscopic life in chronic diseases, Braet F, Weiss A, King N, Dos Remedios C, Traini D, Graeber M, Murphy C, Grau G, Soon L, Newsome T, Goldsbury C, Lovelace M, Gorrell M, Pollock C, DVC Research/Equipment Grant
Robotic High Throughput Western Analysis for the Open Access, Multi-User Sydney Cancer Research Core Facility, Richardson D, Scolyer R, Boyer M, Halliday G, Damian D, Christopherson R, Joshua D, Kench J, Hong A, Murray M, Lee C, Kalinowski D, Naylor M, Lay P, Lyons J, Kovacevic Z, Mason R, Dixon K, Chan-Ling T, Hawkins C, Sunde M, Lovejoy D, Owens T, Rendina L, Jansson P, Dos Remedios C, Charles (nee Slaviero) K, Lane D, Witting P, Dong Q, Ammit A, Groundwater P, Assinder S, Bao B, Byrne S, Zhou F, Buckland M, Grewal T, Huq F, Lai D, Codd R, Zhang D, Fu D, de Graaf S, Huang M, Payne R, Slobedman B, Barrs V, Ho P, Williamson P, Murphy C, DVC Research/Equipment Grant
QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility, Ammit A, Bagley E, Bao B, Boyer M, Byrne M, Camp A, Day M, Dong Q, Dos Remedios C, Fraser S, Fu D, Hanrahan J, Hibbs D, Huang M, Jansson P, Ju Y, Kovacevic Z, Kril J, Lai D, Lane D, Lay P, Lyons J, Morris B, Murphy C, Rendina L, Richardson D, Sutherland G, Vandenberg R, Whittington R, Zhang D, Scolyer R, Black J, Halliday G, Christie M, Zreiqat H, Murray M, Slobedman B, Naylor M, Burgess J, Triccas J, Mason R, Chadban S, Combes V, Lovicu F, McLennan S, Kalinowski D, Sharland A, Johnstone D, Groundwater P, Dixon K, Zhou F, Lovejoy D, Lu Z, Zhu L, Goldsbury C, Witting P, Buckland M, Assinder S, Purdie (Williams) A, Codd R, Owens T, Hambly B, National Health and Medical Research Council (NHMRC)/Equipment Grant

2011

Upgrade of the Palm Duoflex Combi Laser Microdissection and Optical Tweezers System to a High-resolution and Improved Live-cell Imaging Platform using an Apotome.2 Slider and Associated Software, Cole L, Mason R, Richardson D, Phillips W, Bao B, Buckland M, Morris M, Dos Remedios C, Rebecca L Cooper Medical Research Foundation/Equipment Grant
Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer, Baxter R, Halliday G, Marsh D, Gill A, Clarke S, Smith R, Little C, Jackson C, O'Neill C, Murphy C, Sharland A, Chadban S, Mason R, Assinder S, Verdurand M, Richardson D, Machaalani R, Hambly B, Chan-Ling T, Dos Remedios C, Holsinger D, Lay P, National Health and Medical Research Council (NHMRC)/Equipment Grant

2010

PyroMark Q96 ID system, Richardson D, Stone J, Black J, King N, Mason R, Hunt N, Kril J, Murray M, Scolyer R, Halliday G, Vandenberg R, McMinn P, Chadban S, Byrne M, Ryan R, Dong Q, Lee C, Bishop A, Haass N, Fraser S, Hambly B, Sharland A, Kalinowski D, Assinder S, Yu Y, Bao B, Ju Y, Lovejoy D, Buckland M, Lane D, Dos Remedios C, Kovacevic Z, Sutherland G, Zhang D, Morris B, Suryo Rahmanto A, Murphy C, National Health and Medical Research Council (NHMRC)/Equipment Grant
International Union for Pure & Applied Physics, Dos Remedios C, International Union for Pure & Applied Physics/Research Support

2009

A 5-D Correlative Imaging Platform: Combining the Strengths of Light and Electron Microscopy, Braet F, Mitchell H, Soon L, Overall R, Day D, Waterhouse P, Marc J, Conigrave A, Weiss A, Newsome T, Meikle S, Goetz J, Goldsbury C, Hambley T, Ramzan I, Young P, Traini D, Grewal T, Fleming S, Murphy C, Grau G, Weninger W, Dos Remedios C, Wimmer-Kleikamp S, Munroe P, Stevens-Kalceff M, Foster L, Killingsworth M, Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF)
Surface immobilisation of enzymes for the synthesis of ethanol, McKenzie D, Bilek M, Dos Remedios C, Yasuda H, Australian Research Council (ARC)/Discovery Projects (DP)

2008

Muscle Res Dos Remedios Donation as per Q104, Dos Remedios C, Research Donations/Research Donations
Muscle Res Dos Remedios, Dos Remedios C, Imperial College London/Research Support
Muscle Res Dos Remedios, Dos Remedios C, University of the Mediterranean/Research Support

2006

Fluorescence Applications in Biotechnology and Life Sciences (FABLS), Dos Remedios C, Australian Research Council (ARC)/Research Networks (ARCRN)
High-resolution electron tomographic facility for nanoanlytical characterization in the material an, Braet F, Dos Remedios C, Hambley T, Lay P, Liu Z, Murphy C, Parker A, Ramzan I, Ringer S, Soon L, Thordarson P, Warr G, Weiss A, Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF)
Cardiac Gene Expression Profile Of Ageing, Dos Remedios C, DEST/Innovation Access Programme-International Science&Technology Grants

2005

High resolution bioanalytical Fourier transform mass spectrometer combined with liquid chromatograph, Baker M, Cavicchioli R, Christopherson R, Davey R, Dos Remedios C, Geczy C, Guilhaus M, Harry E, James D, Raftery M, Stocker R, Wilkinson M, Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF)

2004

Monitoring Psoriasis treatments with protein microarrays, Barnetson R, Dos Remedios C, Psoriasis Australia Inc/Biennial Research Grant

2003

2100 bioanalyfor multi-user molecular biology facility, Dos Remedios C, Clive & Vera Ramaciotti Foundation/Research Grant
Detection of conformational changes in actin and myosin using fluoresence spectroscopy, Moens P, Dos Remedios C, National Health and Medical Research Council (NHMRC)/Project Grants
Electric field induced surface attachment & detachment of proteins, Dos Remedios C, Griesser H, McKenzie D, Australian Research Council (ARC)/Discovery Projects (DP)

2002

Lipids and the actin cytoskeleton, Dos Remedios C, DVC Research/Research and Development Scheme: Research and Development (R&D)
Ultrasec 3100 pro: UV-vis spectrophotmeter, Byrne M, Dos Remedios C, Keay K, Lovicu F, Mason R, National Health and Medical Research Council (NHMRC)/Equipment Grant
Leica inverted research microscope with photographic attachment, Dos Remedios C, Clive & Vera Ramaciotti Foundation/Project Support

2001

Probing the function of protein molecular motors on nano-fabricated structures, Dos Remedios C, Australian Research Council (ARC)/Discovery Projects (DP)
Inverted micro-nano-fluidics devices using protein molecular motors, Dos Remedios C, Swinburne University of Technology./Research Grant
Inverted micro/nano-fluidics devices using protein molecular motors, Dos Remedios C, Defence Advanced Research Projects Agency/Research Grants
RC L3022 - Diagnosis of leukaemias by CD antigen expression & Protocol No X02-0056 & RC K0301- Inflammation and CD antigen expression: cardiopulmonary bypass v OPCAB surgery, Christopherson R, Dos Remedios C, Medsaic Pty Ltd/BLO Project

2000

The role of cofilin in regulating the actin cytoskeleton, Dos Remedios C, King G, Australian Research Council (ARC)/Large Research Grants (LRG)

1999

Advanced networked PCR system: multi-block system for the control of polymerase chain reaction work in a multi-user environment, Dos Remedios C, Stone J, Clive & Vera Ramaciotti Foundation/Research Grants
A molecular device for the detection of aqueous environmental pollution, Dos Remedios C, Filshie B, Hourigan M, Hermon Slade Foundation/BLO Project
Analysis of structure and function of actin and myosin using fluorescence spectroscopy, Dos Remedios C, National Health and Medical Research Council (NHMRC)/Project Grants
Signalling pathway of cardiomyocyte apoptosis in failing hearts, Dos Remedios C, Jiang L, National Heart Foundation of Australia/Research Grant FPRx139 SCHx1422
A new regulatory mechanism for the actin cytoskeleton, Dos Remedios C, Australian Research Council (ARC)/Small Grants
Fluorescence activated cell sorter, Morris B, Dos Remedios C, Mason R, Clive & Vera Ramaciotti Foundation/Awards for Biomedical Research: Major Equipment

Faculty of Medicine and Health

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Professor Emeritus Cristobal dos Remedios

Selected publications

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