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Dr Danqing Min

Senior Research Fellow
Medicine, Central Clinical School

Telephone 8627 1706
Fax 8627 1604

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Research interests

Dr Min's principal research interests focus on understanding the molecular mechanisms of inflammation responses during the development of diabetic complications which investigating a): the role of monocyte/macrophage in diabetes and diabetic complications. b): the role of the matrix metalloproteinases (MMPs)/ their tissue inhibitors (TIMPs) involved in the development of diabetic complications. c): the targeted gene therapy and combination therapy on control the development of diabetic complications.

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Selected grants

2014

  • Circulating monocyte phenotype: Is it altered in association with the development of diabetic complications; McLennan S, Twigg S, Min D; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
  • Characterization of effect of diabetes on the anti-inflammatory CD163+ monocytes: possible role in the development of diabetic nephropathy; Min D; Diabetes Australia Research Trust (DART)/Research Grants.

2011

  • Preventing Adverse Effects of Matrix Metalloproteinases in Diabetic Wound Healing; McLennan S, Twigg S, Min D, Yue D; National Health and Medical Research Council (NHMRC)/Project Grants.
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Selected publications

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Journals

  • Abdollahi, M., Ng, T., Rezaeizadeh, A., Aamidor, S., Twigg, S., Min, D., McLennan, S. (2017). Insulin treatment prevents wounding associated changes in tissue and circulating neutrophil MMP-9 and NGAL in diabetic rats. PloS One, 12(2), e0170951. [More Information]
  • McLennan, S., Min, D., Wang, X., Twigg, S. (2017). Method for Analysis of Matrix Degradation by CCN2 Through the MMP/TIMP System. Methods in Molecular Biology, CCN Proteins: Methods and Protocols vol.1489, 523-532. [More Information]
  • Min, D., Brooks, B., Wong, J., Aamidor, S., Seehoo, R., Sutanto, S., Harrisberg, B., Yue, D., Twigg, S., McLennan, S. (2016). Monocyte CD163 is altered in association with diabetic complications: possible protective role. Journal of Leukocyte Biology, 100(6), 1375-1383. [More Information]
  • Scott, C., Bonner, J., Min, D., Boughton, P., Stokes, R., Cha, K., Walters, S., Masolowski, K., Sierro, F., Grey, S., Twigg, S., McLennan, S., Gunton, J. (2014). Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing. American Journal of Physiology: Cell Physiology, 307(4), C349-C357. [More Information]
  • Min, D., Brooks, B., Wong, J., Salomon, R., Bao, W., Harrisberg, B., Twigg, S., Yue, D., McLennan, S. (2012). Alterations in Monocyte CD16 in Association with Diabetes Complications. Mediators of Inflammation, 2012, 1-10. [More Information]
  • Bao, W., Min, D., Twigg, S., Shackel, N., Warner, F., Yue, D., McLennan, S. (2010). Monocyte CD147 is induced by advanced glycation end products and high glucose concentration: possible role in diabetic complications. American Journal of Physiology: Cell Physiology, 299(5), C1212-C1219. [More Information]
  • Zheng, G., Lyons, J., Tan, T., Wang, Y., Hsu, T., Min, D., Succar, L., Rangan, G., Hu, M., Henderson, B., Alexander, S., Harris, D. (2009). Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-{beta}1 in Renal Tubular Epithelial Cells. The American Journal of Pathology, 175(2), 580-591. [More Information]
  • Liu, Y., Min, D., Bolton, T., Nube, V., Twigg, S., Yue, D., McLennan, S. (2009). Increased Matrix Metalloproteinase-9 Predicts Poor Wound Healing in Diabetic Foot Ulcers. Diabetes Care, 32(1), 117-119. [More Information]
  • Min, D., Lyons, G., Bonner, J., Twigg, S., Yue, D., McLennan, S. (2009). Mesangial cell-derived factors alter monocyte activation and function through inflammatory pathways: possible pathogenic role in diabetic nephropathy. American Journal of Physiology: Renal Physiology, 297(5), F1229-F1237. [More Information]
  • Wong, J., McLennan, S., Molyneaux, L., Min, D., Twigg, S., Yue, D. (2009). Mitochondrial DNA content in peripheral blood monocytes: relationship with age of diabetes onsetand diabetic complications. Diabetologia, 52, 1953-1961. [More Information]
  • McLennan, S., Min, D., Zaman, S. (2008). Matrix metalloproteinases: their role in poor wound healing in diabetes. Wound Practice & Research, 16, 116-120.
  • Min, D., Lyons, G., Jia, J., Lo, L., McLennan, S. (2006). 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis, 27(2), 357-364. [More Information]
  • Underwood, C., Min, D., Lyons, G., Hambley, T. (2003). The interaction of metal ions and Marimastat with matrix metalloproteinase 9. Journal of Inorganic Biochemistry, 95(2-3), 165-170. [More Information]

2017

  • Abdollahi, M., Ng, T., Rezaeizadeh, A., Aamidor, S., Twigg, S., Min, D., McLennan, S. (2017). Insulin treatment prevents wounding associated changes in tissue and circulating neutrophil MMP-9 and NGAL in diabetic rats. PloS One, 12(2), e0170951. [More Information]
  • McLennan, S., Min, D., Wang, X., Twigg, S. (2017). Method for Analysis of Matrix Degradation by CCN2 Through the MMP/TIMP System. Methods in Molecular Biology, CCN Proteins: Methods and Protocols vol.1489, 523-532. [More Information]

2016

  • Min, D., Brooks, B., Wong, J., Aamidor, S., Seehoo, R., Sutanto, S., Harrisberg, B., Yue, D., Twigg, S., McLennan, S. (2016). Monocyte CD163 is altered in association with diabetic complications: possible protective role. Journal of Leukocyte Biology, 100(6), 1375-1383. [More Information]

2014

  • Scott, C., Bonner, J., Min, D., Boughton, P., Stokes, R., Cha, K., Walters, S., Masolowski, K., Sierro, F., Grey, S., Twigg, S., McLennan, S., Gunton, J. (2014). Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing. American Journal of Physiology: Cell Physiology, 307(4), C349-C357. [More Information]

2012

  • Min, D., Brooks, B., Wong, J., Salomon, R., Bao, W., Harrisberg, B., Twigg, S., Yue, D., McLennan, S. (2012). Alterations in Monocyte CD16 in Association with Diabetes Complications. Mediators of Inflammation, 2012, 1-10. [More Information]

2010

  • Bao, W., Min, D., Twigg, S., Shackel, N., Warner, F., Yue, D., McLennan, S. (2010). Monocyte CD147 is induced by advanced glycation end products and high glucose concentration: possible role in diabetic complications. American Journal of Physiology: Cell Physiology, 299(5), C1212-C1219. [More Information]

2009

  • Zheng, G., Lyons, J., Tan, T., Wang, Y., Hsu, T., Min, D., Succar, L., Rangan, G., Hu, M., Henderson, B., Alexander, S., Harris, D. (2009). Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-{beta}1 in Renal Tubular Epithelial Cells. The American Journal of Pathology, 175(2), 580-591. [More Information]
  • Liu, Y., Min, D., Bolton, T., Nube, V., Twigg, S., Yue, D., McLennan, S. (2009). Increased Matrix Metalloproteinase-9 Predicts Poor Wound Healing in Diabetic Foot Ulcers. Diabetes Care, 32(1), 117-119. [More Information]
  • Min, D., Lyons, G., Bonner, J., Twigg, S., Yue, D., McLennan, S. (2009). Mesangial cell-derived factors alter monocyte activation and function through inflammatory pathways: possible pathogenic role in diabetic nephropathy. American Journal of Physiology: Renal Physiology, 297(5), F1229-F1237. [More Information]
  • Wong, J., McLennan, S., Molyneaux, L., Min, D., Twigg, S., Yue, D. (2009). Mitochondrial DNA content in peripheral blood monocytes: relationship with age of diabetes onsetand diabetic complications. Diabetologia, 52, 1953-1961. [More Information]

2008

  • McLennan, S., Min, D., Zaman, S. (2008). Matrix metalloproteinases: their role in poor wound healing in diabetes. Wound Practice & Research, 16, 116-120.

2006

  • Min, D., Lyons, G., Jia, J., Lo, L., McLennan, S. (2006). 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis, 27(2), 357-364. [More Information]

2003

  • Underwood, C., Min, D., Lyons, G., Hambley, T. (2003). The interaction of metal ions and Marimastat with matrix metalloproteinase 9. Journal of Inorganic Biochemistry, 95(2-3), 165-170. [More Information]
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