Associate Professor Deborah Marsh

Associate Professor & Research Only Academic Level D
Medicine, Northern Clinical School
Kolling Institute of Medical Research

Telephone +61 2 9926 4760
Fax +61 2 9926 8484

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Research interests

The molecular nature of endocrine tumorigenesis

PhD and master's project opportunities

+ indicates the opportunity is full and unavailable.

International links

Sweden

(University Hospital Linkoping, Linkoping) collaborating with Professor Oliver Gimm, focussing on familial endocrine cancers and parathyroid tumorigenesis

United States

(Boston University, MA) collaborating with Dr Muhammad Zaman, focussing on cell migration

United States

(Van Andel Research Institute, Grand Rapids, MI) collaborating with Dr Bin Teh, focussing on the molecular nature of parathyroid tumorigenesis

Selected grants

2014

  • Northern Translational Cancer Research Centre; Engel A, Bailey D, Boyle F, Clarke S, Gill A, Marsh D, Molloy M; Cancer Institute New South Wales/Translational Cancer Research Centre.

2013

  • Serum microRNAs as predictive tools for optimal cytoreduction in women with serous epithelial ovarian cancer; Marsh D, Howell V, Gard G; Ovarian Cancer Research Foundation/Research Support.
  • Monoubiquitinated histone H2B ? marking key pathways in ovarian cancer; Marsh D, Gill A, Gard G; Cancer Council New South Wales/Research Project Grants.
  • A high-throughput, bright-field and fluorescence digital slide scanning platform and service that is both research and teaching-focused and available University-wide.; King N, Graeber M, Naylor M, Slapeta J, Quinnell R, Charles (nee Slaviero) K, Owens T, Bourne R, Braet F, Hambly B, Overall R, Stone J, Twigg S, Hardikar A, Halliday G, Richardson D, Byrne M, Keay K, Marsh D, Howell V, Pollock C, Chen X; DVC Research/Equipment Grant.

2012

  • Maximising support for breast cancer research by the Australian Breast Cancer Tissue Bank; Clarke C, Marsh D, Forbes J, Scott R, Dahlstrom J, Zeps N, Simpson P; National Breast Cancer Foundation/Infrastructure Grant.
  • Data Linkage for NSW Bioresources using CHeReL; Baxter R, Robinson B, Boyle F, Clarke C, Marsh D; Cancer Institute New South Wales/Biobanking Stakeholder Network Funding.
  • Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer; Baxter R, Halliday G, Marsh D, Gill A, Clarke S, Smith R, Little C, Jackson C, O'Neill C, Murphy C, Sharland A, Chadban S, Mason R, Assinder S, Verdurand M, Richardson D, Machaalani R, Hambly B, Chan-Ling T, Dos Remedios C, Holsinger D, Lay P; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2011

  • IncuCyte FLR Microscope System and Cell Incubator; Baxter R, Marsh D, Jackson C, O'Neill C, Ashton A, Howell V; Clive & Vera Ramaciotti Foundation/Awards for Biomedical Research: Major Equipment.
  • IncuCyte FLR Microscope System (Essen Bioscience); Marsh D, Baxter R, Morris J, Jackson C, Howell V; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Understanding endocrine tumorigenesis - opportunities for new diagnostics and therapies; Marsh D; Cancer Institute New South Wales/Career Development Fellowship.
  • Pyk2: a central mediator of gonadotropin action in ovarian cancer; Marsh D, Baxter R; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Understanding endocrine tumorigenesis - opportunities for new diagnostics and therapies; Marsh D; Australian Research Council (ARC)/Future Fellowships (FT).

2010

  • Role of the B-Isoform of the thromboxane A2 receptor in breast cancer; Ashton A, Marsh D; North Sydney Central Coast Area Health Services (NSCCAH)/Research Support.
  • Facilities for cryogenic storage and transport of tissue bank materials; Clarke C, Baxter R, Lee C, Marsh D; Cancer Institute New South Wales/Equipment Grant.
  • In-Vivo Multispectral Imaging FX System: small animal imaging for multi-modal molecular signal localisation in live animals; Marsh D, Baxter R, Ashton A, Howell V, Soon P, Little D, Robinson B; Cancer Institute New South Wales/Equipment Grant.
  • Protein discovery for breast cancer diagnosis; Baxter R, Moore (Loveridge) K, Marsh D, Boyle F, McCarthy N; National Health and Medical Research Council (NHMRC)/Project Grants.
  • New insights into mammalian gene transcription - the role of parafibromin; Marsh D; Australian Research Council (ARC)/Discovery Projects (DP).
  • MMI Smart Cut Plus laser microdissector; Baxter R, Little C, Marsh D, Keast J; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Breast cancer biospecimen resource; Morey A, Forbes J, Scott R, Spigelman A, Clarke C, Kefford R, Baxter R, Marsh D, Friedlander M, Harnett P, Balleine R, Bilous M, Boyages J, Sutherland R; National Health and Medical Research Council (NHMRC)/Enabling Grants.

2009

  • Breast Cancer Tissue Bank - data collection and management infrasture; Clarke C, Scott R, Balleine R, Carpenter J, Baxter R, Bilous M, Lee S, Marsh D, Scott R, Spigelman A; Cancer Institute New South Wales/Infrastructure Grant.
  • Protein discovery for breast cancer diagnosis; Baxter R, Moore (Loveridge) K, Marsh D; DVC Research/Bridging Support Grant.
  • Relationships between miRNA and the phosphatidylinositol 3-kinase/mammamlian target of rapamycin pathway in ovarian cancer; Marsh D, Howell V; DVC Research/Cancer Research Fund.

2008

  • Dako ACIS 111 Cellular Image Acquisition and Analysis System; Hambly B, Bao B, Bishop A, Black J, Campbell I, Dong Q, Gorrell M, Grau G, Hunt N, King N, Markham R, Marsh D, McDonald K, McLennan S, Rodgers K, Seth D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Ovarian Surface Epithelial Carcinoma Modelling in Brac1-null mice mediated by Sleeping Beauty insert; Howell V, Marsh D; Cure Cancer Australia Foundation/Research Support.
  • Dako ACIS III Cellular Image Acquisition and Analysis System; Gorrell M, Grau G, Bishop A, Black J, Campbell I, McLennan S, Rodgers K, Seth D, Marsh D, Dong Q, Hambly B, Bao B, King N, Markham R, McDonald K, Hunt N; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Molecular analysis of endocrine tumours; Marsh D; Cancer Institute New South Wales/Early Career Development Fellowship.

2007

  • Lab-on-a-Chip Technology; Marsh D; University of Sydney/Research Support.
  • Premier's Award for Outstanding Cancer Research Fellow; Marsh D; Cancer Institute New South Wales/Research Grant.
  • Tumour bank officer in the Northern Hub; Smith R, Marsh D, Baxter R, Robinson B; Cancer Institute New South Wales/Infrastructure Grant.
  • Breast Cancer Tissue Bank; Marsh D, Clarke C, Scott R, Kefford R, Balleine R, Baxter R, Bilous M, Carpenter J, Friedlander M, Forbes J, Boyages J, Spigelman A, Sutherland R, Harnett P, Morey A; National Breast Cancer Foundation/Research Grants.

2006

  • Biomarkers of cell signalling pathways on ovarian cancer; Marsh D, Baxter R; Cancer Council New South Wales/Research Project Grants.
  • FAXSCalibur 4 -colour Flow Cytometer; Baxter R, Firth S, Marsh D, Schedlich L, Scott C, Martin J, Robinson B; Cancer Institute New South Wales/Research Grants Program - Category 2.
  • Wash System for Beckman 3000 Laboratory Automation System; Baxter R, Marsh D; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • University of Sydney - Bridging Support Grant; Marsh D; University of Sydney/Bridging Support.
  • Fiberlite: Carbon fiber composite rotors; Firth S, Chen X, Marsh D, Benn D; University of Sydney/Research Support.

2005

  • Multifunction Imaging System; Firth S, McCracken S, Marsh D, Chen X; University of Sydney/Research Support.
  • Automated Precision Liquid Handling System; Benn D, Chen X, Chung L, Baxter R, Marsh D, Robinson B, Firth S; University of Sydney/Research Support.
  • Breast Cancer biospecimen resource; Boyages J, Spigelman A, Forbes J, Marsh D, Friedlander M, Morey A, Spigelman A, Sutherland R, Scott R, Balleine R, Baxter R, Bilous M, Kefford R, Clarke C; National Breast Cancer Foundation/Grant-in-Aid.
  • Breast cancer biospecimen resource; Marsh D, Clarke C, Harnett P, Spigelman A, Forbes J, Harnett P, Friedlander M, Sutherland R, Boyages J, Morey A, Spigelman A, Scott R, Balleine R, Baxter R, Bilous M, Kefford R; Cancer Institute New South Wales/Research Grant.
  • Identification of novel protein binding partners of the putative tumour suppressor HRPT2/parafibromin; Hahn M, Marsh D; Cure Cancer Australia Foundation/Research Support.
  • Investigation of the chemokine CXCL 1 as a biomarker of growth factor signalling in ovarian cancer; Marsh D, Baxter R; University of Sydney/Cancer Research Fund.
  • Cancer Inst NSW Fell05-Marsh; Marsh D; Cancer Institute New South Wales/Research Grant.
  • Cancer functional genomics in the northern hub; Baxter R, Marsh D, Smith R; Cancer Institute New South Wales/Research Grant.

2004

  • Breast cancer biospecimen resource; Clarke C, Balleine R, Bilous M, Kefford R, Baxter R, Harnett P, Spigelman A, Forbes J, Spigelman A, Marsh D, Boyages J, Friedlander M, Harnett P, Morey A, Scott R, Sutherland R; National Health and Medical Research Council (NHMRC)/Enabling Grants.
  • Expression of the novel gene HRPT2: preliminary investigation of the role of parafibromin; Marsh D; DVC Research/Research and Development Scheme: Research and Development (R&D).
  • Parathyroid tumorigenesis - a role for the newly identified putative tumour supressor HRPT2; Marsh D, Robinson B; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Multiple Block Thermal Cycler; Marsh D, Hahn M; University of Sydney/Research Support.
  • NanoDrop ND-1000 spectrometer plus computer; Marsh D, Firth S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2003

  • Tissue Arrayer to Facilitate the Identification of Differentially Expressed Proteins in Multiple Tum; Marsh D; University of Sydney/Research Support.
  • Retsch MM 301 mixer mill; 2 x adaptor racks; Marsh D; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2001

  • The identification of novel genes involved in the intiation and development of thyroid neoplasia; Marsh D, Robinson B; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Multiple block thermal cycler; Marsh D, Nelson N; University of Sydney/Research Support.
  • The identification of novel genes involved in the initiation and development of thyroid neoplasia; National Health and Medical Research Council (NHMRC)/Established Career Fellowships.

2000

  • Purchase of a PhosphorImager to serve a multi-departmental function; Marsh D, Nelson N; University of Sydney/Research Support.
  • Genetic Studies of Endocrine Tumours - purchase of a Corbett Research Gel Scan 2000 DNA Fragment A; Marsh D, Robinson B; Rebecca L Cooper Medical Research Foundation/Research Support.

1999

  • Use of the cytogenetic technique comparative genomic hybridisation (CGH) for the identification of novel oncogenes and tumor suppressor genes; Marsh D, Robinson B; Clive & Vera Ramaciotti Foundation/Research Grants.

Selected publications

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Book Chapters

  • Marsh, D., Howell, V. (2010). The Use of Denaturing High Performance Liquid Chromatography (DHPLC) for Mutation Scanning of Hereditary Cancer Genes. In Michelle Webb (Eds.), Cancer Susceptibility: Methods and Protocols, (pp. 133-145). United States: Humana Press.
  • Marsh, D., Zori, R. (2008). Cowden Syndrome. In Manfred Schwab (Eds.), Encyclopedia of Cancer, Vol. 1. Germany: Springer.
  • Marsh, D., Zori, R. (2005). Cowden Syndrome. In Fuchs J and Podda M (Eds.), Encyclopaedia of Diagnostics Genomics and Proteomics, (pp. 301-304). New York, USA: Marcel Dekker.
  • Marsh, D., Benn, D. (2005). Von Hippel-Lindau Disease. In Fuchs J and Podda M (Eds.), Encyclopaedia of Diagnostics Genomics and Proteomics, (pp. 1329-1333). New York, USA: Marcel Dekker.
  • Marsh, D., Zori, R. (2001). Cowden Syndrome. In Schwab M (Eds.), Encyclopedic Reference of Cancer, (pp. 222-226). United States: Springer.
  • Marsh, D., Stratakis, C. (2001). Hamartoma Syndromes: Harmatoma and Lentiginosis Syndromes: Clinical and Molecular Aspects. In Patricia L.M. Dahlia, Charis Eng and Grossman AB (Eds.), Genetic Disorders of Endocrine Neoplasia, Vol. 28, (pp. 167-213). Switzerland: S. Karger AG.

Journals

  • Garcia-Closas, M., Couch, F., Lindstrom, S., Michailidou, K., Schmidt, M., Brook, M., Orr, N., Rhie, S., Riboli, E., Feigelson, H., Carpenter, J., Balleine, R., et al (2013). Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nature Genetics, 45(4), 392-398. [More Information]
  • Chung, L., Shibli, S., Moore, K., Elder, E., Boyle, F., Marsh, D., Baxter, R. (2013). Tissue biomarkers of breast cancer and their association with conventional pathologic features. British Journal of Cancer, 108(2), 351-360. [More Information]
  • Kan, C., Hahn, M., Gard, G., Maidens, J., Huh, J., Marsh, D., Howell, V. (2012). Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer. BMC Cancer, 12, 1-9. [More Information]
  • Mertens, I., Baxter, R., Marsh, D. (2012). Gonadotropin signalling in epithelial ovarian cancer. Cancer Letters, 324(2), 152-159. [More Information]
  • Paul, R., Elston, M., Gill, A., Marsh, D., Beer, I., Wolmarans, L., Conaglen, J., Meyer-Rochow, G. (2012). Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology, 52(2), 204-207. [More Information]
  • Gribben, L., Baxter, R., Marsh, D. (2012). Insulin-like growth factor binding protein-3 inhibits migration of endometrial cancer cells. Cancer Letters, 317(1), 41-48. [More Information]
  • Hahn, M., Dickson, K., Jackson, S., Clarkson, A., Gill, A., Marsh, D. (2012). The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. Human Molecular Genetics, 21(3), 559-568. [More Information]
  • Lin, W., Martin, J., Marsh, D., Jack, M., Baxter, R. (2011). Involvement of insulin-like growth factor binding protein-3 in the effects of the histone deacetylase inhibitor MS-275 in hepatoma cells. Journal of Biological Chemistry, 286(34), 29540-29547. [More Information]
  • Lim, S., Elston, M., Gill, A., Marsh, D., Conaglen, J. (2011). Metastatic parathyroid carcinoma initially misdiagnosed as parathyroid adenoma: The role of parafibromin in increasing diagnostic accuracy. Internal Medicine Journal, 41(9), 695-699. [More Information]
  • Marsh, D., Gimm, O. (2011). Multiple endocrine neoplasia: types 1 and 2. Advances in Oto-Rhino-Laryngology, 70(-), 84-90. [More Information]
  • Marsh, D., Trahair, T., Kirk, E. (2011). Mutant AKT1 in Proteus syndrome. The New England Journal of Medicine, 365(22), 2141-2142. [More Information]
  • Hahn, M., Howell, V., Gill, A., Clarkson, A., Weaire-Buchanan, G., Robinson, B., Delbridge, L., Gimm, O., Schmitt, W., Teh, B., Marsh, D. (2010). CDC73/HRPT2 CpG island hypermethylation and mutation of 5'-untranslated sequence are uncommon mechanisms of silencing parafibromin in parathyroid tumors. Endocrine-Related Cancer, 17(1), 273-282. [More Information]
  • Mertens, I., Bolitho (nee Donald), C., Baxter, R., Marsh, D. (2010). Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. Endocrine-Related Cancer, 17(2), 335-349. [More Information]
  • Bolitho (nee Donald), C., Hahn, M., Baxter, R., Marsh, D. (2010). The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor. Endocrine-Related Cancer, 17(4), 929-940. [More Information]
  • Howell, V., Gill, A., Clarkson, A., Nelson, A., Dunne, R., Delbridge, L., Robinson, B., Teh, B., Gimm, O., Marsh, D. (2009). Accuracy of Combined Protein Gene Product 9.5 and Parafibromin Markers for Immunohistochemical Diagnosis of Parathyroid Carcinoma. Journal of Clinical Endocrinology and Metabolism, 94(2), 434-441. [More Information]
  • Meyer-Rochow, G., Smith, J., Richardson, A., Marsh, D., Sidhu, S., Robinson, B., Benn, D. (2009). Denaturing High Performance Liquid Chromatography Detection of SDHB, SDHD, and VHL Germline Mutations in Pheochromocytoma. Journal of Surgical Research, 157, 55-62. [More Information]
  • Hahn, M., McDonnell, J., Marsh, D. (2009). The effect of disease-associated HRPT2 mutations on splicing. Journal of Endocrinology, 201(3), 387-396. [More Information]
  • Marsh, D., Trahair, T., Martin, J., Chee, W., Walker, J., Kirk, E., Baxter, R., Marshall, G. (2008). Rapamycin treatment for a child with germline PTEN mutation. Nature Clinical Practice Oncology, 5(6), 357-361. [More Information]
  • Marsh, D., Hahn, M., Howell, V., Gill, A. (2007). Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes. Expert Opinion on Medical Diagnostics, 1(3), 377-392.
  • Hahn, M., Marsh, D. (2007). Nucleolar localization of parafibromin is mediated by three nucleolar localization signals. FEBS Letters, 581(26), 5070-5074. [More Information]
  • Benn, D., Marsh, D., Robinson, B., Riches, J. (2006). Genetic testing in pheochromocytoma- and paraganglioma-associated syndromes. New York Academy of Sciences. Annals, 1073, 104-111. [More Information]
  • Gill, A., Clarkson, A., Gimm, O., Keil, J., Dralle, H., Howell, V., Marsh, D. (2006). Loss of Nuclear Expression of Parafibromin Distinguishes Parathyroid Carcinomas and Hyperparathyroidism-Jaw Tumor (HPT-JT) Syndrome-related Adenomas From Sporadic Parathyroid Adenomas and Hyperplasias. American Journal of Surgical Pathology, 30(9), 1140-1149. [More Information]
  • Gimm, O., Lorenz, K., Nguyen Thanh, P., Schneyer, U., Bloching, M., Howell, V., Marsh, D., Teh, B., Krause, U., Dralle, H. (2006). Prophylactic parathyroidectomy for familial parathyroid carcinoma. Chirurg, 77(1), 15-24. [More Information]
  • Marsh, D., Baxter, R., Moscova, M. (2006). Protein chip discovery of secreted proteins regulated by the phosphatidylinositol 3-kinase pathway in ovarian cancer cell lines. Cancer Research, 66(3), 1376-1383. [More Information]
  • Howell, V., Cardinal, J., Richardson, A., Gimm, O., Robinson, B., Marsh, D. (2006). Rapid Mutation Screening for HRPT2 and MEN1 Mutations Associated with Familial and Sporadic Primary Hyperparathyroidism. Journal of molecular diagnostics, 8(5), 559-566. [More Information]
  • Dahia, P., Ross, K., Wright, M., Hayashida, C., Santagata, S., Barontini, M., Kung, A., Sanso, G., Powers, J., Benn, D., Marsh, D., Robinson, B., et al (2005). A HIF1-alpha Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas. PLoS Genetics, 1(1), 72-80. [More Information]
  • Benn, D., Gimenez-Roqueplo, A., Reilly, J., Bertherat, J., Burgess, J., Byth Wilson, K., Croxson, M., Dahia, P., Elston, M., Gimm, O., Marsh, D., Robinson, B., et al (2005). Clinical presentation and penetrance of Pheochromocytoma/ Paraganglioma syndromes. Journal of Clinical Endocrinology and Metabolism, 91(3), 827-836. [More Information]
  • Hahn, M., Marsh, D. (2005). Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin. Oncogene, 24(41), 6241-6248. [More Information]
  • Howell, V., Zori, R., Stalker, H., Williams, C., Jesse, N., Nelson, A., Robinson, B., Marsh, D. (2004). A molecular diagnosis of hyperparathyroidism-Jaw tumor syndrome in an adolescent with recurrent kidney stones. The Journal of Pediatrics, 145(4), 567-567.
  • Kirk, E., Smith, J., Field, M., Marshall, G., Marsh, D. (2004). Diagnosis of Proteus Syndrome was correct. American Journal of Medical Genetics. Part A, 130A (2), 214-215. [More Information]
  • Haven, C., Howell, V., Eilers, P., Dunne, R., Takahashi, M., Van Puijenbroek, M., Furge, K., Kievit, J., Tan, M., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Nelson, A., Marsh, D., et al (2004). Gene Expression Of Parathyroid Tumors: Molecular Subclassification And Identification Of The Potential Malignant Phenotype. Cancer Research, 64(20), 7405-7411.
  • Marsh, D., Morreau, H., Teh, B. (2004). HRPT2 and parathyroid cancer. Lancet Oncology, 5(2), 78-78.
  • McDonnell, C., Benn, D., Marsh, D., Robinson, B., Zacharin, M. (2004). K40E: A Novel Succinate Dehydrogenase (Sdh)B Mutation Causing Familial Phaeochromocytoma And Paraganglioma. Clinical Endocrinology, 61(4), 510-514.
  • Marsh, D. (2003). "Endocrine Tumors" - book review. Cancer Forum, 11, 1810-181.
  • Bernard, M., Sidhu, S., Berger, N., Peix, J., Marsh, D., Robinson, B., Gaston, V., Le Bouc, Y., Gicquel, C. (2003). A case report in favor of a multistep adrenocortical tumorigenesis. Journal of Clinical Endocrinology and Metabolism, 88(3), 998-1001.
  • Marsh, D., Gimm, O. (2003). Does a somatic deletion in RET clarify the sporadic nature of medullary thryoid carcinoma? Journal Of Endocrinological Investigation, 11, 381-383.
  • Marsh, D., Theodosopoulos, G., Martin-Schulte, K., Richardson, A., Philips, J., Roher, H., Delbridge, L., Robinson, B. (2003). Genome-wide copy number imbalances identified in familial and sproadic medullary thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism, 88(4), 1866-1872.
  • Zhou, X., Marsh, D., Morrison, C., Chaudhury, A., Maxwell, M., Reifenberger, G., Eng, C. (2003). Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults. American Journal of Human Genetics, 73(5), 1191-1198.
  • Howell, V., Haven, C., Kahnoski, K., Khoo, S., Petillo, D., Chen, J., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Marsh, D., et al (2003). HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours. Journal of Medical Genetics, 40(9), 657-663.
  • Benn, D., Croxson, M., Tucker, K., Bambach, C., Richardson, A., Delbridge, L., Pullan, P., Hammond, J., Marsh, D., Robinson, B. (2003). Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporatid phaeochromaocytomas. Oncogene, 22(9), 1358-1364.
  • Sidhu, S., Marsh, D., Theodosopoulos, G., Philips, J., Bambach, C., Campbell, P., Magarey, C., Russell, C., Martin-Schulte, K., Roher, H., Delbridge, L., Robinson, B. (2002). Comparative genomic hybridization analysis of adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 87(7), 3467-3474.
  • Dwight, T., Philips, J., Robinson, B., Twigg, S., Kytola, S., Delbridge, L., Teh, B., Marsh, D., Theodosopoulos, G., Nelson, A., et al (2002). Genetic analysis of lithium-associated parathyroid tumors. European Journal of Endocrinology, 146(5), 619-627.
  • Marsh, D., Zori, R. (2002). Genetic insights into familial cancers - update and recent discoveries. Cancer Letters, 181(2), 125-164.
  • Benn, D., Marsh, D., Robinson, B. (2002). Genetics of pheochromocytoma and paraganglioma. Current Opinion in Endocrinology, Diabetes and Obesity, 9(1), 79-86.
  • Smith, J., Kirk, E., Theodosopoulos, G., Marshall, G., Walker, J., Rogers, M., Field, M., Brereton, J., Marsh, D. (2002). Germline mutation of the tumour suppressor PTEN in Proteus syndrome. Journal of Medical Genetics, 39, 937-940.
  • Dwight, T., Nelson, A., Theodosopoulos, G., Richardson, A., Learoyd, D., Philips, J., Delbridge, L., Zedenius, J., Teh, B., Larsson, C., Marsh, D., Robinson, B. (2002). Independent Genetic Events Associated with the Development of Multiple Parathyroid Tumors in Patients with Primary Hyperparqathyroidism. The American Journal of Pathology: cellular and molecular biology of disease, 161(4), 1299-1306.
  • Nelson, A., Robinson, B., Marsh, D., Dwight, T., Teh, B., Larsson, C. (2002). Parathyroid tumorigenesis in association with primary hyperparathyroidism. Current Opinion in Endocrinology, Diabetes and Obesity, , 51-60.
  • Andrew, S., Capes-Davis, A., Delhanty, P., Marsh, D., Mulligan, L., Robinson, B. (2002). Transcriptional repression of the RET proto-oncogene by a mitogen activated protein kinase-dependent signalling pathway. Gene, 298(1), 9-19.
  • Marsh, D., Robinson, B., Fackenthal, J., Riches, J., Cummings, S., Eng,, C., Olopade, O. (2001). Male breast cancer in Cowden syndrome patients with germline PTEN mutations. Journal of Medical Genetics, 38, 159-164.
  • Nelson, A., Robinson, B., Mason, R., Marsh, D., Holm,, I., Cowell, C., Carpenter, T. (2001). Mutational analysis and genotype-phenotype correlation of the PHEX gene in X-Linked hypophosphphatiemic rickets. Journal of Clinical Endocrinology and Metabolism, 86(8), 3889-3899.
  • Marsh, D., Howell, V., Benn, D., Robinson, B., Theodosopoulos, G., Riches, J., Proos, A., Eng,, C. (2001). Rapid mutation scanning of genes associated with familial cancer syndromes using denaturing high-performance liquid chromatography. Neoplasia (Spanish Edition): oncologia multidisciplinaria, 3, 236-244.

Conferences

  • Moscova, M., Marsh, D., Baxter, R. (2005). Identification of Cytokines regulated by phosphatidylinositol-3 kinase in ovarian cancer. AACR-NCI-EORTC International Conference 2005, United States: American Association for Cancer Research.

2013

  • Garcia-Closas, M., Couch, F., Lindstrom, S., Michailidou, K., Schmidt, M., Brook, M., Orr, N., Rhie, S., Riboli, E., Feigelson, H., Carpenter, J., Balleine, R., et al (2013). Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nature Genetics, 45(4), 392-398. [More Information]
  • Chung, L., Shibli, S., Moore, K., Elder, E., Boyle, F., Marsh, D., Baxter, R. (2013). Tissue biomarkers of breast cancer and their association with conventional pathologic features. British Journal of Cancer, 108(2), 351-360. [More Information]

2012

  • Kan, C., Hahn, M., Gard, G., Maidens, J., Huh, J., Marsh, D., Howell, V. (2012). Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer. BMC Cancer, 12, 1-9. [More Information]
  • Mertens, I., Baxter, R., Marsh, D. (2012). Gonadotropin signalling in epithelial ovarian cancer. Cancer Letters, 324(2), 152-159. [More Information]
  • Paul, R., Elston, M., Gill, A., Marsh, D., Beer, I., Wolmarans, L., Conaglen, J., Meyer-Rochow, G. (2012). Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology, 52(2), 204-207. [More Information]
  • Gribben, L., Baxter, R., Marsh, D. (2012). Insulin-like growth factor binding protein-3 inhibits migration of endometrial cancer cells. Cancer Letters, 317(1), 41-48. [More Information]
  • Hahn, M., Dickson, K., Jackson, S., Clarkson, A., Gill, A., Marsh, D. (2012). The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination. Human Molecular Genetics, 21(3), 559-568. [More Information]

2011

  • Lin, W., Martin, J., Marsh, D., Jack, M., Baxter, R. (2011). Involvement of insulin-like growth factor binding protein-3 in the effects of the histone deacetylase inhibitor MS-275 in hepatoma cells. Journal of Biological Chemistry, 286(34), 29540-29547. [More Information]
  • Lim, S., Elston, M., Gill, A., Marsh, D., Conaglen, J. (2011). Metastatic parathyroid carcinoma initially misdiagnosed as parathyroid adenoma: The role of parafibromin in increasing diagnostic accuracy. Internal Medicine Journal, 41(9), 695-699. [More Information]
  • Marsh, D., Gimm, O. (2011). Multiple endocrine neoplasia: types 1 and 2. Advances in Oto-Rhino-Laryngology, 70(-), 84-90. [More Information]
  • Marsh, D., Trahair, T., Kirk, E. (2011). Mutant AKT1 in Proteus syndrome. The New England Journal of Medicine, 365(22), 2141-2142. [More Information]

2010

  • Hahn, M., Howell, V., Gill, A., Clarkson, A., Weaire-Buchanan, G., Robinson, B., Delbridge, L., Gimm, O., Schmitt, W., Teh, B., Marsh, D. (2010). CDC73/HRPT2 CpG island hypermethylation and mutation of 5'-untranslated sequence are uncommon mechanisms of silencing parafibromin in parathyroid tumors. Endocrine-Related Cancer, 17(1), 273-282. [More Information]
  • Mertens, I., Bolitho (nee Donald), C., Baxter, R., Marsh, D. (2010). Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. Endocrine-Related Cancer, 17(2), 335-349. [More Information]
  • Bolitho (nee Donald), C., Hahn, M., Baxter, R., Marsh, D. (2010). The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor. Endocrine-Related Cancer, 17(4), 929-940. [More Information]
  • Marsh, D., Howell, V. (2010). The Use of Denaturing High Performance Liquid Chromatography (DHPLC) for Mutation Scanning of Hereditary Cancer Genes. In Michelle Webb (Eds.), Cancer Susceptibility: Methods and Protocols, (pp. 133-145). United States: Humana Press.

2009

  • Howell, V., Gill, A., Clarkson, A., Nelson, A., Dunne, R., Delbridge, L., Robinson, B., Teh, B., Gimm, O., Marsh, D. (2009). Accuracy of Combined Protein Gene Product 9.5 and Parafibromin Markers for Immunohistochemical Diagnosis of Parathyroid Carcinoma. Journal of Clinical Endocrinology and Metabolism, 94(2), 434-441. [More Information]
  • Meyer-Rochow, G., Smith, J., Richardson, A., Marsh, D., Sidhu, S., Robinson, B., Benn, D. (2009). Denaturing High Performance Liquid Chromatography Detection of SDHB, SDHD, and VHL Germline Mutations in Pheochromocytoma. Journal of Surgical Research, 157, 55-62. [More Information]
  • Hahn, M., McDonnell, J., Marsh, D. (2009). The effect of disease-associated HRPT2 mutations on splicing. Journal of Endocrinology, 201(3), 387-396. [More Information]

2008

  • Marsh, D., Zori, R. (2008). Cowden Syndrome. In Manfred Schwab (Eds.), Encyclopedia of Cancer, Vol. 1. Germany: Springer.
  • Marsh, D., Trahair, T., Martin, J., Chee, W., Walker, J., Kirk, E., Baxter, R., Marshall, G. (2008). Rapamycin treatment for a child with germline PTEN mutation. Nature Clinical Practice Oncology, 5(6), 357-361. [More Information]

2007

  • Marsh, D., Hahn, M., Howell, V., Gill, A. (2007). Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes. Expert Opinion on Medical Diagnostics, 1(3), 377-392.
  • Hahn, M., Marsh, D. (2007). Nucleolar localization of parafibromin is mediated by three nucleolar localization signals. FEBS Letters, 581(26), 5070-5074. [More Information]

2006

  • Benn, D., Marsh, D., Robinson, B., Riches, J. (2006). Genetic testing in pheochromocytoma- and paraganglioma-associated syndromes. New York Academy of Sciences. Annals, 1073, 104-111. [More Information]
  • Gill, A., Clarkson, A., Gimm, O., Keil, J., Dralle, H., Howell, V., Marsh, D. (2006). Loss of Nuclear Expression of Parafibromin Distinguishes Parathyroid Carcinomas and Hyperparathyroidism-Jaw Tumor (HPT-JT) Syndrome-related Adenomas From Sporadic Parathyroid Adenomas and Hyperplasias. American Journal of Surgical Pathology, 30(9), 1140-1149. [More Information]
  • Gimm, O., Lorenz, K., Nguyen Thanh, P., Schneyer, U., Bloching, M., Howell, V., Marsh, D., Teh, B., Krause, U., Dralle, H. (2006). Prophylactic parathyroidectomy for familial parathyroid carcinoma. Chirurg, 77(1), 15-24. [More Information]
  • Marsh, D., Baxter, R., Moscova, M. (2006). Protein chip discovery of secreted proteins regulated by the phosphatidylinositol 3-kinase pathway in ovarian cancer cell lines. Cancer Research, 66(3), 1376-1383. [More Information]
  • Howell, V., Cardinal, J., Richardson, A., Gimm, O., Robinson, B., Marsh, D. (2006). Rapid Mutation Screening for HRPT2 and MEN1 Mutations Associated with Familial and Sporadic Primary Hyperparathyroidism. Journal of molecular diagnostics, 8(5), 559-566. [More Information]

2005

  • Dahia, P., Ross, K., Wright, M., Hayashida, C., Santagata, S., Barontini, M., Kung, A., Sanso, G., Powers, J., Benn, D., Marsh, D., Robinson, B., et al (2005). A HIF1-alpha Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas. PLoS Genetics, 1(1), 72-80. [More Information]
  • Benn, D., Gimenez-Roqueplo, A., Reilly, J., Bertherat, J., Burgess, J., Byth Wilson, K., Croxson, M., Dahia, P., Elston, M., Gimm, O., Marsh, D., Robinson, B., et al (2005). Clinical presentation and penetrance of Pheochromocytoma/ Paraganglioma syndromes. Journal of Clinical Endocrinology and Metabolism, 91(3), 827-836. [More Information]
  • Marsh, D., Zori, R. (2005). Cowden Syndrome. In Fuchs J and Podda M (Eds.), Encyclopaedia of Diagnostics Genomics and Proteomics, (pp. 301-304). New York, USA: Marcel Dekker.
  • Hahn, M., Marsh, D. (2005). Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin. Oncogene, 24(41), 6241-6248. [More Information]
  • Moscova, M., Marsh, D., Baxter, R. (2005). Identification of Cytokines regulated by phosphatidylinositol-3 kinase in ovarian cancer. AACR-NCI-EORTC International Conference 2005, United States: American Association for Cancer Research.
  • Marsh, D., Benn, D. (2005). Von Hippel-Lindau Disease. In Fuchs J and Podda M (Eds.), Encyclopaedia of Diagnostics Genomics and Proteomics, (pp. 1329-1333). New York, USA: Marcel Dekker.

2004

  • Howell, V., Zori, R., Stalker, H., Williams, C., Jesse, N., Nelson, A., Robinson, B., Marsh, D. (2004). A molecular diagnosis of hyperparathyroidism-Jaw tumor syndrome in an adolescent with recurrent kidney stones. The Journal of Pediatrics, 145(4), 567-567.
  • Kirk, E., Smith, J., Field, M., Marshall, G., Marsh, D. (2004). Diagnosis of Proteus Syndrome was correct. American Journal of Medical Genetics. Part A, 130A (2), 214-215. [More Information]
  • Haven, C., Howell, V., Eilers, P., Dunne, R., Takahashi, M., Van Puijenbroek, M., Furge, K., Kievit, J., Tan, M., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Nelson, A., Marsh, D., et al (2004). Gene Expression Of Parathyroid Tumors: Molecular Subclassification And Identification Of The Potential Malignant Phenotype. Cancer Research, 64(20), 7405-7411.
  • Marsh, D., Morreau, H., Teh, B. (2004). HRPT2 and parathyroid cancer. Lancet Oncology, 5(2), 78-78.
  • McDonnell, C., Benn, D., Marsh, D., Robinson, B., Zacharin, M. (2004). K40E: A Novel Succinate Dehydrogenase (Sdh)B Mutation Causing Familial Phaeochromocytoma And Paraganglioma. Clinical Endocrinology, 61(4), 510-514.

2003

  • Marsh, D. (2003). "Endocrine Tumors" - book review. Cancer Forum, 11, 1810-181.
  • Bernard, M., Sidhu, S., Berger, N., Peix, J., Marsh, D., Robinson, B., Gaston, V., Le Bouc, Y., Gicquel, C. (2003). A case report in favor of a multistep adrenocortical tumorigenesis. Journal of Clinical Endocrinology and Metabolism, 88(3), 998-1001.
  • Marsh, D., Gimm, O. (2003). Does a somatic deletion in RET clarify the sporadic nature of medullary thryoid carcinoma? Journal Of Endocrinological Investigation, 11, 381-383.
  • Marsh, D., Theodosopoulos, G., Martin-Schulte, K., Richardson, A., Philips, J., Roher, H., Delbridge, L., Robinson, B. (2003). Genome-wide copy number imbalances identified in familial and sproadic medullary thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism, 88(4), 1866-1872.
  • Zhou, X., Marsh, D., Morrison, C., Chaudhury, A., Maxwell, M., Reifenberger, G., Eng, C. (2003). Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults. American Journal of Human Genetics, 73(5), 1191-1198.
  • Howell, V., Haven, C., Kahnoski, K., Khoo, S., Petillo, D., Chen, J., Fleuren, G., Robinson, B., Delbridge, L., Philips, J., Marsh, D., et al (2003). HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours. Journal of Medical Genetics, 40(9), 657-663.
  • Benn, D., Croxson, M., Tucker, K., Bambach, C., Richardson, A., Delbridge, L., Pullan, P., Hammond, J., Marsh, D., Robinson, B. (2003). Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporatid phaeochromaocytomas. Oncogene, 22(9), 1358-1364.

2002

  • Sidhu, S., Marsh, D., Theodosopoulos, G., Philips, J., Bambach, C., Campbell, P., Magarey, C., Russell, C., Martin-Schulte, K., Roher, H., Delbridge, L., Robinson, B. (2002). Comparative genomic hybridization analysis of adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 87(7), 3467-3474.
  • Dwight, T., Philips, J., Robinson, B., Twigg, S., Kytola, S., Delbridge, L., Teh, B., Marsh, D., Theodosopoulos, G., Nelson, A., et al (2002). Genetic analysis of lithium-associated parathyroid tumors. European Journal of Endocrinology, 146(5), 619-627.
  • Marsh, D., Zori, R. (2002). Genetic insights into familial cancers - update and recent discoveries. Cancer Letters, 181(2), 125-164.
  • Benn, D., Marsh, D., Robinson, B. (2002). Genetics of pheochromocytoma and paraganglioma. Current Opinion in Endocrinology, Diabetes and Obesity, 9(1), 79-86.
  • Smith, J., Kirk, E., Theodosopoulos, G., Marshall, G., Walker, J., Rogers, M., Field, M., Brereton, J., Marsh, D. (2002). Germline mutation of the tumour suppressor PTEN in Proteus syndrome. Journal of Medical Genetics, 39, 937-940.
  • Dwight, T., Nelson, A., Theodosopoulos, G., Richardson, A., Learoyd, D., Philips, J., Delbridge, L., Zedenius, J., Teh, B., Larsson, C., Marsh, D., Robinson, B. (2002). Independent Genetic Events Associated with the Development of Multiple Parathyroid Tumors in Patients with Primary Hyperparqathyroidism. The American Journal of Pathology: cellular and molecular biology of disease, 161(4), 1299-1306.
  • Nelson, A., Robinson, B., Marsh, D., Dwight, T., Teh, B., Larsson, C. (2002). Parathyroid tumorigenesis in association with primary hyperparathyroidism. Current Opinion in Endocrinology, Diabetes and Obesity, , 51-60.
  • Andrew, S., Capes-Davis, A., Delhanty, P., Marsh, D., Mulligan, L., Robinson, B. (2002). Transcriptional repression of the RET proto-oncogene by a mitogen activated protein kinase-dependent signalling pathway. Gene, 298(1), 9-19.

2001

  • Marsh, D., Zori, R. (2001). Cowden Syndrome. In Schwab M (Eds.), Encyclopedic Reference of Cancer, (pp. 222-226). United States: Springer.
  • Marsh, D., Stratakis, C. (2001). Hamartoma Syndromes: Harmatoma and Lentiginosis Syndromes: Clinical and Molecular Aspects. In Patricia L.M. Dahlia, Charis Eng and Grossman AB (Eds.), Genetic Disorders of Endocrine Neoplasia, Vol. 28, (pp. 167-213). Switzerland: S. Karger AG.
  • Marsh, D., Robinson, B., Fackenthal, J., Riches, J., Cummings, S., Eng,, C., Olopade, O. (2001). Male breast cancer in Cowden syndrome patients with germline PTEN mutations. Journal of Medical Genetics, 38, 159-164.
  • Nelson, A., Robinson, B., Mason, R., Marsh, D., Holm,, I., Cowell, C., Carpenter, T. (2001). Mutational analysis and genotype-phenotype correlation of the PHEX gene in X-Linked hypophosphphatiemic rickets. Journal of Clinical Endocrinology and Metabolism, 86(8), 3889-3899.
  • Marsh, D., Howell, V., Benn, D., Robinson, B., Theodosopoulos, G., Riches, J., Proos, A., Eng,, C. (2001). Rapid mutation scanning of genes associated with familial cancer syndromes using denaturing high-performance liquid chromatography. Neoplasia (Spanish Edition): oncologia multidisciplinaria, 3, 236-244.

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