Associate Professor Freddy Sitas

Adjunct Associate Professor
Public Health, School of Public Health

Telephone +61 2 9334 1860
Fax +61 2 9334 1778

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Biographical details

Freddy Sitas obtained a BSc in 1981, an MSC(MED) in 1987 from the University of the Witwatersrand (South Africa), an MSC in Epidemiology from the London School of Hygiene and Tropical Medicine in 1987, and a DPhil in Epidemiology from the University of Oxford in 1990. Part of his work showed for the first time that Helicobacter pylori is a cause of stomach cancer. He returned to South Africa in 1990 to the position of Head of the National Cancer Registry and in 1999 became Head of the South African MRC Cancer Epidemiology Research Group. In 2000, he was awarded a Readership in Epidemiology by the University of the Witwatersrand.

He was appointed Director of the Cancer Research Division at Cancer Council NSW in 2003.

Research interests

A/Prof Sitas' interests include cancer and mortality surveillance, viruses and cancer, and tobacco attributed disease.

Currently, Freddy is a Chief Investigator on the Cervical Health Study, The Cancer Lifestyle, Evaluation And Risk Study (CLEAR), The ABC Breast Cancer Study, the Skin Health Study and the InterSCOPE study.

International links

France

(Interantional Agency for Research on Cancer) Working group: 100th Monograph on carcinogenicity (Part B -Biological agents) Advisor to IARC on cancer registration in low and middle income countries

France

(International Agency for Research on Cancer) Developing a standardised risk factor questionnaire for studues of cancer causes

Germany

(German Cancer Research Centre) With Dr Michael Pawlita and colleagues on the InterSCOPE project and NHMRC funded Infection, lifestyle and Skin cancer project.

South Africa

(Medical Research Council, Burden of Disease Unit) With Debbie Bradshaw and Colleagues, on tobacco attributed mortality

South Africa

(National Health Laboratory Service, Cancer Epidemiolgy Research Group) Co-PI with Margaret Urban on Johannesburg cancer case control study, examining lifestyle and infectious causes of cancer

United Kingdom

(Cancer Research UK, Cancer Epidemiology Unit, Univ. Oxford.) With Professor Valerie Beral, Advisor on NSW Cancer, Lifestyle and Evaluation of Risk study.

United Kingdom

(University of Oxford, Clinical Trials Service Unit) With Sir Richard Peto, on a study of tobacco attributed deaths on the South African Death notification form

United States

(National Cancer Institute) With DCEG, on the Interscope study

Selected publications

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Journals

  • Sitas, F., Gibberd, A., Kahn, C., Weber, M., Chiew, M., Supramaniam, R., Velentzis, L., Nickson, C., Smith, D., O'Connell, D., Yu, X., Canfell, K., Robotin, M., et al (2013). Cancer incidence and mortality in people aged less than 75 years: Changes in Australia over the period 1987-2007. Cancer Epidemiology, 37(6), 780-787. [More Information]
  • Sitas, F., Egger, S., Bradshaw, D., Groenewald, P., Laubscher, R., Kielkowski, D., Peto, R. (2013). Differences among the coloured, white, black, and other South African populations in smoking-attributed mortality at ages 35-74 years: a case-control study of 481,640 deaths. The Lancet, 382(9893), 685-693. [More Information]
  • Weber, M., Smith, D., O'Connell, D., Patel, M., De Souza, P., Sitas, F., Banks, E. (2013). Risk factors for erectile dysfunction in a cohort of 108 477 Australian men. Medical Journal of Australia, 199(2), 107-111. [More Information]
  • Weber, M., Cunich, M., Smith, D., Salkeld, G., Sitas, F., O'Connell, D. (2013). Sociodemographic and health-related predictors of self-reported mammogram, faecal occult blood test and prostate specific antigen test use in a large Australian study. BMC Public Health, 13(429), 1-13. [More Information]
  • Chiew, M., Weber, M., Egger, S., Sitas, F. (2012). A cross-sectional exploration of smoking status and social interaction in a large population-based Australian cohort. Social Science and Medicine, 75(1), 77-86. [More Information]
  • Urban, M., Banks, E., Egger, S., Canfell, K., O'Connell, D., Beral, V., Sitas, F. (2012). Injectable and Oral Contraceptive Use and Cancers of the Breast, Cervix, Ovary, and Endometrium in Black South African women: Case-Control study. PLoS Medicine, 9(3), 1-11. [More Information]
  • Sitas, F., Egger, S., Urban, M., Taylor, P., Abnet, C., Boffetta, P., O'Connell, D., Whiteman, D., Brennan, P., Malekzadeh, R., et al (2012). InterSCOPE Study: Associations Between Esophageal Squamous Cell Carcinoma and Human Papillomavirus Serological Markers. National Cancer Institute. Journal, 104(2), 147-158. [More Information]
  • Weber, M., Banks, E., Sitas, F. (2011). Smoking in migrants in New South Wales, Australia: Report on data from over 100,000 participants in the 45 and Up Study. Drug and Alcohol Review, 30(6), 597-605. [More Information]
  • Sitas, F., Yu, X., O'Connell, D., Blizzard, L., Otahal, P., Newman, L., venn, A. (2011). The relationship between basal and squamous cell skin cancer and smoking related cancers. BMC Research Notes, 4(1), Article 556 - 1-Article 556 - 5. [More Information]
  • Willcox, S., Stewart, B., Sitas, F. (2011). What factors do cancer patients believe contribute to the development of their cancer? Cancer Causes and Control, 22, 1503-1511. [More Information]
  • Sitas, F., O'Connell, D., Van Kemenade, C., Short, M., Zhao, K. (2010). Breast cancer risk among female employees of the Australian Broadcasting Corporation in Australia. Medical Journal of Australia, 192(11), 651-654. [More Information]
  • Jiang, J., Liu, B., Sitas, F., Zeng, X., Chen, J., Han, W., Zou, X., Wu, Y., Zhao, P., Li, J. (2010). Case-spouse control design in practice: an experience in estimating smoking and chronic obstructive pulmonary disease deaths in Chinese adults. Journal Of The Formosan Medical Association, 109(5), 369-377. [More Information]
  • Malope-Kgokong Babatyi I, B., Macphail, P., Mbisa, G., Ratshikhopa, E., Maskew, M., Stein, L., Sitas, F., Whitby, D. (2010). Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa. Infectious Agents and Cancer, 5, 14. [More Information]
  • Jiang, J., Liu, B., Sitas, F., Li, J., Zeng, X., Han, W., Zou, X., Wu, Y., Zhao, P. (2010). Smoking-attributable deaths and potential years of life lost from a large, representative study in China. Tobacco Control, 19(1), 7-12. [More Information]
  • Weber, M., Banks, E., Smith, D., O'Connell, D., Sitas, F. (2009). Cancer screening among migrants in an Australian cohort; cross-sectional analyses from the 45 and Up Study. BMC Public Health, 2009 (9), 144-52. [More Information]
  • Sitas, F., O'Connell, D., Jamrozik, K., Lopez, A. (2009). Smoking questions on the Australian death notification form: adopting international best practice? Medical Journal of Australia, 191(3), 166-168. [More Information]
  • Mayosi, B., Flisher, A., Lalloo, U., Sitas, F., Tollman, S., Bradshaw, D. (2009). The burden of non-communicable diseases in South Africa. The Lancet, 374(9693), 934-947. [More Information]
  • Stein, L., Weber, M., Ruff, P., Hale, M., Donde, B., Patel, M., Sitas, F. (2008). Effects of tobacco smoking on cancer and cardiovascular disease in urban black South Africans. British Journal of Cancer, 98(9), 1586-1592. [More Information]
  • Supramaniam, R., O'Connell, D., Robotin, M., Tracey, E., Sitas, F. (2008). Future cancer trends to be influenced by past and future migration. Australian and New Zealand Journal of Public Health, 32(1), 90-92. [More Information]
  • Malope, B., Macphail, P., Mbisa, G., Stein, L., Ratshikhopha, E., Ndhlovu, L., Sitas, F., Whitby, D. (2008). No evidence of sexual transmission of Kaposi's sarcoma herpes virus in a heterosexual South African population. AIDS, 22(4), 519-526. [More Information]
  • Parkin, D., Sitas, F., Chirenje, M., Stein, L., Abratt, R., Wabinga, H. (2008). Part I: Cancer in Indigenous Africans--burden, distribution, and trends. The Lancet Oncology, 9(7), 683-692. [More Information]
  • Sitas, F., Parkin, D., Chirenje, M., Stein, L., Abratt, R., Wabinga, H. (2008). Part II: Cancer in Indigenous Africans-causes and control. The Lancet Oncology, 9(8), 786-795. [More Information]
  • Weber, M., Banks, E., Ward, R., Sitas, F. (2008). Population characteristics related to colorectal cancer testing in New South Wales, Australia: results from the 45 and Up Study cohort. Journal of Medical Screening, 15(3), 137-142. [More Information]
  • Robotin, M., George, J., Supramaniam, R., Sitas, F., Penman, A. (2008). Preventing primary liver cancer: how well are we faring towards a national hepatitis B strategy? Medical Journal of Australia, 188(6), 363-365. [More Information]
  • Stein, L., Urban, M., O'Connell, D., Yu, X., Beral, V., Newton, R., Ruff, P., Donde, B., Hale, M., Patel, M., Sitas, F. (2008). The spectrum of human immunodeficiency virus-associated cancers in a South African black population: results from a case-control study, 1995-2004. International Journal of Cancer, 122(10), 2260-2265. [More Information]
  • Sitas, F., Urban, M., Stein, L., Beral, V., Ruff, P., Hale, M., Patel, M., O'Connell, D., Yu Xue, Q., Verzijden, A., et al (2007). The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population. Infectious Agents and Cancer, 2(1), online 1-online 9. [More Information]
  • Marais, D., Sampson, C., Urban, M., Sitas, F., Williamson, A. (2007). The seroprevalence of IgG antibodies to human papillomavirus (HPV) types HPV-16, HPV-18, and HPV-11 capsid-antigens in mothers and their children. Journal of Medical Virology, 79(9), 1370-1374.
  • Berrington-González, A., Urban, M., Sitas, F., Blackburn, N., Hale, M., Patel, M., Ruff, P., Sur, R., Newton, R., Beral, V. (2006). Antibodies against six human herpesviruses in relation to seven cancers in black South Africans: A case control study. Infectious Agents and Cancer, 1, 2-2. [More Information]
  • Canfell, K., Sitas, F., Beral, V. (2006). Cervical cancer in Australia and the United Kingdom: comparison of screening policy and uptake, and cancer incidence and mortality. Medical Journal of Australia, 185(9), 482-486. [More Information]
  • Malope, B., Pfeiffer, R., Mbisa, G., Stein, L., Ratshikhopha, E., O'Connell, D., Sitas, F., Macphail, P., Whitby, D. (2006). Transmission of Kaposi Sarcoma-Associated Herpesvirus Between Mothers and Children in a South African Population. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 44(3), 351-355. [More Information]
  • Weir, L., Spigelman, A., Scott, R., Kirk, J., Zeckendorf, S., Sitas, F. (2005). The NSW & ACT Hereditary Cancer Registers. Australian Family Physician, 34(1-2), 53-58. [More Information]
  • Mosane, T., Malope, B., Ratshikhopha, M., Hiss, D., Sitas, F. (2004). Seroprevalence of Helicobacter pylori immunoglobulin G antibodies in South African mothers and their children. European Journal of Gastroenterology and Hepatology, 16(1), 113-114.
  • Sitas, F., Dedicoat, M., Newton, R. (2003). Cancer in rural KwaZulu-Natal. SAMJ South African Medical Journal, 93(11), 846-847.
  • Wojcicki, J., Newton, R., Urban, M., Stein, L., Hale, M., Patel, M., Ruff, P., Sur, R., Bourboulia, D., Sitas, F. (2003). Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study. BMC Infectious Diseases, 3(1), 21.

2013

  • Sitas, F., Gibberd, A., Kahn, C., Weber, M., Chiew, M., Supramaniam, R., Velentzis, L., Nickson, C., Smith, D., O'Connell, D., Yu, X., Canfell, K., Robotin, M., et al (2013). Cancer incidence and mortality in people aged less than 75 years: Changes in Australia over the period 1987-2007. Cancer Epidemiology, 37(6), 780-787. [More Information]
  • Sitas, F., Egger, S., Bradshaw, D., Groenewald, P., Laubscher, R., Kielkowski, D., Peto, R. (2013). Differences among the coloured, white, black, and other South African populations in smoking-attributed mortality at ages 35-74 years: a case-control study of 481,640 deaths. The Lancet, 382(9893), 685-693. [More Information]
  • Weber, M., Smith, D., O'Connell, D., Patel, M., De Souza, P., Sitas, F., Banks, E. (2013). Risk factors for erectile dysfunction in a cohort of 108 477 Australian men. Medical Journal of Australia, 199(2), 107-111. [More Information]
  • Weber, M., Cunich, M., Smith, D., Salkeld, G., Sitas, F., O'Connell, D. (2013). Sociodemographic and health-related predictors of self-reported mammogram, faecal occult blood test and prostate specific antigen test use in a large Australian study. BMC Public Health, 13(429), 1-13. [More Information]
  • Feletto, E., Gibberd, A., Kahn, C., Armstrong, K., Canfell, K., Chiew, M., Grogan, P., Nickson, C., OConnell, D., Penman, A., Robotin, M., Smith, D., Yu, X., Sitas, F., et al (2013), The State of Cancer Control in Australia 1987–2007: Changes in cancer incidence and mortality. , , , 1-166.

2012

  • Chiew, M., Weber, M., Egger, S., Sitas, F. (2012). A cross-sectional exploration of smoking status and social interaction in a large population-based Australian cohort. Social Science and Medicine, 75(1), 77-86. [More Information]
  • Urban, M., Banks, E., Egger, S., Canfell, K., O'Connell, D., Beral, V., Sitas, F. (2012). Injectable and Oral Contraceptive Use and Cancers of the Breast, Cervix, Ovary, and Endometrium in Black South African women: Case-Control study. PLoS Medicine, 9(3), 1-11. [More Information]
  • Sitas, F., Egger, S., Urban, M., Taylor, P., Abnet, C., Boffetta, P., O'Connell, D., Whiteman, D., Brennan, P., Malekzadeh, R., et al (2012). InterSCOPE Study: Associations Between Esophageal Squamous Cell Carcinoma and Human Papillomavirus Serological Markers. National Cancer Institute. Journal, 104(2), 147-158. [More Information]

2011

  • Weber, M., Banks, E., Sitas, F. (2011). Smoking in migrants in New South Wales, Australia: Report on data from over 100,000 participants in the 45 and Up Study. Drug and Alcohol Review, 30(6), 597-605. [More Information]
  • Sitas, F., Yu, X., O'Connell, D., Blizzard, L., Otahal, P., Newman, L., venn, A. (2011). The relationship between basal and squamous cell skin cancer and smoking related cancers. BMC Research Notes, 4(1), Article 556 - 1-Article 556 - 5. [More Information]
  • Willcox, S., Stewart, B., Sitas, F. (2011). What factors do cancer patients believe contribute to the development of their cancer? Cancer Causes and Control, 22, 1503-1511. [More Information]

2010

  • Sitas, F., O'Connell, D., Van Kemenade, C., Short, M., Zhao, K. (2010). Breast cancer risk among female employees of the Australian Broadcasting Corporation in Australia. Medical Journal of Australia, 192(11), 651-654. [More Information]
  • Jiang, J., Liu, B., Sitas, F., Zeng, X., Chen, J., Han, W., Zou, X., Wu, Y., Zhao, P., Li, J. (2010). Case-spouse control design in practice: an experience in estimating smoking and chronic obstructive pulmonary disease deaths in Chinese adults. Journal Of The Formosan Medical Association, 109(5), 369-377. [More Information]
  • Malope-Kgokong Babatyi I, B., Macphail, P., Mbisa, G., Ratshikhopa, E., Maskew, M., Stein, L., Sitas, F., Whitby, D. (2010). Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa. Infectious Agents and Cancer, 5, 14. [More Information]
  • Jiang, J., Liu, B., Sitas, F., Li, J., Zeng, X., Han, W., Zou, X., Wu, Y., Zhao, P. (2010). Smoking-attributable deaths and potential years of life lost from a large, representative study in China. Tobacco Control, 19(1), 7-12. [More Information]

2009

  • Weber, M., Banks, E., Smith, D., O'Connell, D., Sitas, F. (2009). Cancer screening among migrants in an Australian cohort; cross-sectional analyses from the 45 and Up Study. BMC Public Health, 2009 (9), 144-52. [More Information]
  • Sitas, F., O'Connell, D., Jamrozik, K., Lopez, A. (2009). Smoking questions on the Australian death notification form: adopting international best practice? Medical Journal of Australia, 191(3), 166-168. [More Information]
  • Mayosi, B., Flisher, A., Lalloo, U., Sitas, F., Tollman, S., Bradshaw, D. (2009). The burden of non-communicable diseases in South Africa. The Lancet, 374(9693), 934-947. [More Information]

2008

  • Stein, L., Weber, M., Ruff, P., Hale, M., Donde, B., Patel, M., Sitas, F. (2008). Effects of tobacco smoking on cancer and cardiovascular disease in urban black South Africans. British Journal of Cancer, 98(9), 1586-1592. [More Information]
  • Supramaniam, R., O'Connell, D., Robotin, M., Tracey, E., Sitas, F. (2008). Future cancer trends to be influenced by past and future migration. Australian and New Zealand Journal of Public Health, 32(1), 90-92. [More Information]
  • Malope, B., Macphail, P., Mbisa, G., Stein, L., Ratshikhopha, E., Ndhlovu, L., Sitas, F., Whitby, D. (2008). No evidence of sexual transmission of Kaposi's sarcoma herpes virus in a heterosexual South African population. AIDS, 22(4), 519-526. [More Information]
  • Parkin, D., Sitas, F., Chirenje, M., Stein, L., Abratt, R., Wabinga, H. (2008). Part I: Cancer in Indigenous Africans--burden, distribution, and trends. The Lancet Oncology, 9(7), 683-692. [More Information]
  • Sitas, F., Parkin, D., Chirenje, M., Stein, L., Abratt, R., Wabinga, H. (2008). Part II: Cancer in Indigenous Africans-causes and control. The Lancet Oncology, 9(8), 786-795. [More Information]
  • Weber, M., Banks, E., Ward, R., Sitas, F. (2008). Population characteristics related to colorectal cancer testing in New South Wales, Australia: results from the 45 and Up Study cohort. Journal of Medical Screening, 15(3), 137-142. [More Information]
  • Robotin, M., George, J., Supramaniam, R., Sitas, F., Penman, A. (2008). Preventing primary liver cancer: how well are we faring towards a national hepatitis B strategy? Medical Journal of Australia, 188(6), 363-365. [More Information]
  • Stein, L., Urban, M., O'Connell, D., Yu, X., Beral, V., Newton, R., Ruff, P., Donde, B., Hale, M., Patel, M., Sitas, F. (2008). The spectrum of human immunodeficiency virus-associated cancers in a South African black population: results from a case-control study, 1995-2004. International Journal of Cancer, 122(10), 2260-2265. [More Information]

2007

  • Sitas, F., Urban, M., Stein, L., Beral, V., Ruff, P., Hale, M., Patel, M., O'Connell, D., Yu Xue, Q., Verzijden, A., et al (2007). The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population. Infectious Agents and Cancer, 2(1), online 1-online 9. [More Information]
  • Marais, D., Sampson, C., Urban, M., Sitas, F., Williamson, A. (2007). The seroprevalence of IgG antibodies to human papillomavirus (HPV) types HPV-16, HPV-18, and HPV-11 capsid-antigens in mothers and their children. Journal of Medical Virology, 79(9), 1370-1374.

2006

  • Berrington-González, A., Urban, M., Sitas, F., Blackburn, N., Hale, M., Patel, M., Ruff, P., Sur, R., Newton, R., Beral, V. (2006). Antibodies against six human herpesviruses in relation to seven cancers in black South Africans: A case control study. Infectious Agents and Cancer, 1, 2-2. [More Information]
  • Canfell, K., Sitas, F., Beral, V. (2006). Cervical cancer in Australia and the United Kingdom: comparison of screening policy and uptake, and cancer incidence and mortality. Medical Journal of Australia, 185(9), 482-486. [More Information]
  • Malope, B., Pfeiffer, R., Mbisa, G., Stein, L., Ratshikhopha, E., O'Connell, D., Sitas, F., Macphail, P., Whitby, D. (2006). Transmission of Kaposi Sarcoma-Associated Herpesvirus Between Mothers and Children in a South African Population. JAIDS-Journal of Acquired Immune Deficiency Syndromes, 44(3), 351-355. [More Information]

2005

  • Weir, L., Spigelman, A., Scott, R., Kirk, J., Zeckendorf, S., Sitas, F. (2005). The NSW & ACT Hereditary Cancer Registers. Australian Family Physician, 34(1-2), 53-58. [More Information]

2004

  • Mosane, T., Malope, B., Ratshikhopha, M., Hiss, D., Sitas, F. (2004). Seroprevalence of Helicobacter pylori immunoglobulin G antibodies in South African mothers and their children. European Journal of Gastroenterology and Hepatology, 16(1), 113-114.

2003

  • Sitas, F., Dedicoat, M., Newton, R. (2003). Cancer in rural KwaZulu-Natal. SAMJ South African Medical Journal, 93(11), 846-847.
  • Wojcicki, J., Newton, R., Urban, M., Stein, L., Hale, M., Patel, M., Ruff, P., Sur, R., Bourboulia, D., Sitas, F. (2003). Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study. BMC Infectious Diseases, 3(1), 21.

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