Dr Galina Schevzov

Paediatrics & Child Health, Children's Hospital, Westmead

Telephone +61 2 98453116
Fax 98453376

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Selected grants

2005

  • Molecular genetics of cell and tissue structure; Gunning P, Schevzov G; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Curthoys, N., Freittag, H., Connor, A., Desouza, M., Brettle, M., Poljak, A., Hall, A., Hardeman, E., Schevzov, G., Gunning, P., et al (2014). Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells. Molecular and Cellular Neuroscience, 58, 11-21. [More Information]
  • Stehn, J., Haass, N., Bonello, T., Desouza, M., Kottyan, G., Treutlein, H., Zeng, J., Nascimento, P., Sequeira, V., Butler, T., Allanson, M., Winlaw, D., Reeve, V., Weninger, W., et al (2013). A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells. Cancer Research, 73(16), 5169-5182. [More Information]
  • Hook, J., Lemckert, F., Schevzov, G., Fath, T., Gunning, P. (2011). Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability. Bioarchitecture, 1(1), 49-59. [More Information]
  • Martin, C., Schevzov, G., Gunning, P. (2010). Alternatively spliced N-terminal exons in tropomyosin isoforms do not act as autonomous targeting signals. Journal of Structural Biology, 170(2), 286-293. [More Information]
  • Fath, T., Chan, Y., Vrhovski, B., Clarke, H., Curthoys, N., Hook, J., Lemckert, F., Schevzov, G., Tam, P., Watson, C., Gunning, P., et al (2010). New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. European Journal of Cell Biology, 89(7), 489-498. [More Information]
  • Bach, C., Schevzov, G., Bryce, N., Gunning, P., O'Neill, G. (2010). Tropomyosin isoform modulation of focal adhesion structure and cell migration. Cell Adhesion and Migration, 4(2), 226-234. [More Information]
  • Lee, A., Kahatapitiya, P., Kramer, B., Joya, J., Hook, J., Liu, R., Schevzov, G., Alexander, I., McCowage, G., Montarras, D., Gunning, P., et al (2009). Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle. Stem Cells: the international journal of cell differentiation and proliferation, 27, 1098-1108. [More Information]
  • Bach, C., Creed, S., Zhong, J., Mahmassani, M., Schevzov, G., Stehn, J., Cowell, L., Naumanen, P., Lappalainen, P., Gunning, P., O'Neill, G. (2009). Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Molecular and Cellular Biology, 29(6), 1506-1514. [More Information]
  • Schevzov, G., Fath, T., Vrhoski, B., Vlahovich, N., Rajan, S., Hook, J., Joya, J., Lemckert, F., Puttur, F., Lin, J., Hardeman, E., O'Neill, G., Gunning, P., et al (2008). Divergent regulation of the sarcomere and the cytoskeleton. Journal of Biological Chemistry, 283(1), 275-283. [More Information]
  • Schevzov, G., O'Neill, G. (2008). Tropomyosin gene expression in vivo and in vitro. Advances in Experimental Medicine and Biology, 644, 45-59. [More Information]
  • Vlahovich, N., Schevzov, G., Nair-Shalliker, V., Ilkovski, B., Artap, S., Joya, J., Kee, A., North, K., Gunning, P., Hardeman, E. (2007). Tropomyosin 4 defines novel filaments in skeletal muscle associated with muscle remodelling/regeneration in normal and diseased muscle. Cell Motility and the Cytoskeleton, 65(online 29 Oct 2007), 73-85. [More Information]
  • Stehn, J., Schevzov, G., O'Neill, G., Gunning, P. (2006). Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy. Current Cancer Drug Targets, 6(3), 245-256. [More Information]
  • Vrhovski, B., McKay, K., Schevzov, G., Gunning, P., Weinberger, R. (2005). Smooth Muscle-specific alpha Tropomyosin Is a Marker of Fully Differentiated Smooth Muscle in Lung. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 53(7), 875-883. [More Information]
  • Schevzov, G., Bryce, N., Almonte-Baldonado, R., Joya, J., Lin, J., Hardeman, E., Weinberger, R., Gunning, P. (2005). Specific Features of Neuronal Size and Shape Are Regulated by Tropomyosin Isoforms. Molecular Biology of the Cell, 16(7), 3425-3437. [More Information]
  • Schevzov, G., Vrhovski, B., Bryce, N., Elmir, S., Qiu, M., O'Neill, G., Yang, N., Verrills, N., Kavallaris, M., Gunning, P. (2005). Tissue-specific Tropomyosin Isoform Composition. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 53(5), 557-570. [More Information]
  • Gunning, P., Schevzov, G., Kee, A., Hardeman, E. (2005). Tropomyosin isoforms: divining rods for actin cytoskeleton function. Trends in Cell Biology, 15(6), 333-341. [More Information]
  • Lloyd, C., Berendse, M., Lloyd, D., Schevzov, G., Grounds, M. (2004). A Novel Role For Non-Muscle Gamma-Actin In Skeletal Muscle Sarcomere Assembly. Experimental Cell Research: emphasizing molecular approaches to cell biology, 297(1), 82-96.
  • Hook, J., Lemckert, F., Qin, H., Schevzov, G., Gunning, P. (2004). Gamma Tropomyosin Gene Products Are Required For Embryonic Development. Molecular and Cellular Biology, 24(6), 2318-2323.
  • Kee, A., Schevzov, G., Nair-Shalliker, V., Robinson, C., Vrhovski, B., Ghoddusi, M., Qiu, M., Lin, J., Weinberger, R., Gunning, P., Hardeman, E. (2004). Sorting Of A Nonmuscle Tropomyosin To A Novel Cytoskeletal Compartment In Skeletal Muscle Results In Muscular Dystrophy. The Journal of Cell Biology, 166(5), 685-696.
  • Percival, J., Hughes, J., Brown, D., Schevzov, G., Heimann, K., Vrhovski, B., Bryce, N., Stow, J., Gunning, P. (2004). Targeting Of A Tropomyosin Isoform To Short Microfilaments Associated With The Golgi Complex. Molecular Biology of the Cell, 15(1), 268-280.
  • Hughes, J., Cooke-Yarborough, C., Chadwick, N., Schevzov, G., Arbuckle, S., Gunning, P., Weinberger, R. (2003). High-molecular-weight tropomyosins localized to the contractile rings of dividing CNS cells but are absent from malignang pediatric and adult CNS tumors. Glia, 42(1), 25-35. [More Information]
  • Bryce, N., Schevzov, G., Ferguson, V., Percival, J., Lin, J., Matsumura, F., Bamburg, J., Jeffrey, P., Hardeman, E., Gunning, P., Weinberger, R. (2003). Specification of actin filament function and molecular composition by tropomyosin isoforms. Molecular Biology of the Cell, 14(3), 1002-1016.
  • Vrhovski, B., Schevzov, G., Dingle, S., Lessard, J., Gunning, P., Weinberger, R. (2003). Tropomyosin Isoforms from the gamma gene differing at the C-Terminus are spatially and devlopmentally regulated in the brain. Journal of Neuroscience Research, 72(3), 373-383. [More Information]
  • Hong, X., Schevzov, G., Gunning, P., Williams, H., Silink, M. (2002). A comparative study of growth-inhibitory effects on isoflavones and their metabolites on human breast and prostate cancer cell lines. Nutrition and Cancer: an international journal, 42(2), 224-232.
  • Weinberger, R., Gunning, P., Schevzov, G. (2000). Staying in shape. Life Science Today, 12, 14-19.

2014

  • Curthoys, N., Freittag, H., Connor, A., Desouza, M., Brettle, M., Poljak, A., Hall, A., Hardeman, E., Schevzov, G., Gunning, P., et al (2014). Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells. Molecular and Cellular Neuroscience, 58, 11-21. [More Information]

2013

  • Stehn, J., Haass, N., Bonello, T., Desouza, M., Kottyan, G., Treutlein, H., Zeng, J., Nascimento, P., Sequeira, V., Butler, T., Allanson, M., Winlaw, D., Reeve, V., Weninger, W., et al (2013). A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells. Cancer Research, 73(16), 5169-5182. [More Information]

2011

  • Hook, J., Lemckert, F., Schevzov, G., Fath, T., Gunning, P. (2011). Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability. Bioarchitecture, 1(1), 49-59. [More Information]

2010

  • Martin, C., Schevzov, G., Gunning, P. (2010). Alternatively spliced N-terminal exons in tropomyosin isoforms do not act as autonomous targeting signals. Journal of Structural Biology, 170(2), 286-293. [More Information]
  • Fath, T., Chan, Y., Vrhovski, B., Clarke, H., Curthoys, N., Hook, J., Lemckert, F., Schevzov, G., Tam, P., Watson, C., Gunning, P., et al (2010). New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. European Journal of Cell Biology, 89(7), 489-498. [More Information]
  • Bach, C., Schevzov, G., Bryce, N., Gunning, P., O'Neill, G. (2010). Tropomyosin isoform modulation of focal adhesion structure and cell migration. Cell Adhesion and Migration, 4(2), 226-234. [More Information]

2009

  • Lee, A., Kahatapitiya, P., Kramer, B., Joya, J., Hook, J., Liu, R., Schevzov, G., Alexander, I., McCowage, G., Montarras, D., Gunning, P., et al (2009). Methylguanine DNA methyltransferase-mediated drug resistance-based selective enrichment and engraftment of transplanted stem cells in skeletal muscle. Stem Cells: the international journal of cell differentiation and proliferation, 27, 1098-1108. [More Information]
  • Bach, C., Creed, S., Zhong, J., Mahmassani, M., Schevzov, G., Stehn, J., Cowell, L., Naumanen, P., Lappalainen, P., Gunning, P., O'Neill, G. (2009). Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Molecular and Cellular Biology, 29(6), 1506-1514. [More Information]

2008

  • Schevzov, G., Fath, T., Vrhoski, B., Vlahovich, N., Rajan, S., Hook, J., Joya, J., Lemckert, F., Puttur, F., Lin, J., Hardeman, E., O'Neill, G., Gunning, P., et al (2008). Divergent regulation of the sarcomere and the cytoskeleton. Journal of Biological Chemistry, 283(1), 275-283. [More Information]
  • Schevzov, G., O'Neill, G. (2008). Tropomyosin gene expression in vivo and in vitro. Advances in Experimental Medicine and Biology, 644, 45-59. [More Information]

2007

  • Vlahovich, N., Schevzov, G., Nair-Shalliker, V., Ilkovski, B., Artap, S., Joya, J., Kee, A., North, K., Gunning, P., Hardeman, E. (2007). Tropomyosin 4 defines novel filaments in skeletal muscle associated with muscle remodelling/regeneration in normal and diseased muscle. Cell Motility and the Cytoskeleton, 65(online 29 Oct 2007), 73-85. [More Information]

2006

  • Stehn, J., Schevzov, G., O'Neill, G., Gunning, P. (2006). Specialisation of the tropomyosin composition of actin filaments provides new potential targets for chemotherapy. Current Cancer Drug Targets, 6(3), 245-256. [More Information]

2005

  • Vrhovski, B., McKay, K., Schevzov, G., Gunning, P., Weinberger, R. (2005). Smooth Muscle-specific alpha Tropomyosin Is a Marker of Fully Differentiated Smooth Muscle in Lung. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 53(7), 875-883. [More Information]
  • Schevzov, G., Bryce, N., Almonte-Baldonado, R., Joya, J., Lin, J., Hardeman, E., Weinberger, R., Gunning, P. (2005). Specific Features of Neuronal Size and Shape Are Regulated by Tropomyosin Isoforms. Molecular Biology of the Cell, 16(7), 3425-3437. [More Information]
  • Schevzov, G., Vrhovski, B., Bryce, N., Elmir, S., Qiu, M., O'Neill, G., Yang, N., Verrills, N., Kavallaris, M., Gunning, P. (2005). Tissue-specific Tropomyosin Isoform Composition. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology, 53(5), 557-570. [More Information]
  • Gunning, P., Schevzov, G., Kee, A., Hardeman, E. (2005). Tropomyosin isoforms: divining rods for actin cytoskeleton function. Trends in Cell Biology, 15(6), 333-341. [More Information]

2004

  • Lloyd, C., Berendse, M., Lloyd, D., Schevzov, G., Grounds, M. (2004). A Novel Role For Non-Muscle Gamma-Actin In Skeletal Muscle Sarcomere Assembly. Experimental Cell Research: emphasizing molecular approaches to cell biology, 297(1), 82-96.
  • Hook, J., Lemckert, F., Qin, H., Schevzov, G., Gunning, P. (2004). Gamma Tropomyosin Gene Products Are Required For Embryonic Development. Molecular and Cellular Biology, 24(6), 2318-2323.
  • Kee, A., Schevzov, G., Nair-Shalliker, V., Robinson, C., Vrhovski, B., Ghoddusi, M., Qiu, M., Lin, J., Weinberger, R., Gunning, P., Hardeman, E. (2004). Sorting Of A Nonmuscle Tropomyosin To A Novel Cytoskeletal Compartment In Skeletal Muscle Results In Muscular Dystrophy. The Journal of Cell Biology, 166(5), 685-696.
  • Percival, J., Hughes, J., Brown, D., Schevzov, G., Heimann, K., Vrhovski, B., Bryce, N., Stow, J., Gunning, P. (2004). Targeting Of A Tropomyosin Isoform To Short Microfilaments Associated With The Golgi Complex. Molecular Biology of the Cell, 15(1), 268-280.

2003

  • Hughes, J., Cooke-Yarborough, C., Chadwick, N., Schevzov, G., Arbuckle, S., Gunning, P., Weinberger, R. (2003). High-molecular-weight tropomyosins localized to the contractile rings of dividing CNS cells but are absent from malignang pediatric and adult CNS tumors. Glia, 42(1), 25-35. [More Information]
  • Bryce, N., Schevzov, G., Ferguson, V., Percival, J., Lin, J., Matsumura, F., Bamburg, J., Jeffrey, P., Hardeman, E., Gunning, P., Weinberger, R. (2003). Specification of actin filament function and molecular composition by tropomyosin isoforms. Molecular Biology of the Cell, 14(3), 1002-1016.
  • Vrhovski, B., Schevzov, G., Dingle, S., Lessard, J., Gunning, P., Weinberger, R. (2003). Tropomyosin Isoforms from the gamma gene differing at the C-Terminus are spatially and devlopmentally regulated in the brain. Journal of Neuroscience Research, 72(3), 373-383. [More Information]

2002

  • Hong, X., Schevzov, G., Gunning, P., Williams, H., Silink, M. (2002). A comparative study of growth-inhibitory effects on isoflavones and their metabolites on human breast and prostate cancer cell lines. Nutrition and Cancer: an international journal, 42(2), 224-232.

2000

  • Weinberger, R., Gunning, P., Schevzov, G. (2000). Staying in shape. Life Science Today, 12, 14-19.

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