Professor Geoffrey Tofler

Professor
Medicine, Northern Clinical School

Telephone 9926 6359

Map

Research interests

prevention of cardiovascular disease, heart failure, thrombosis, exercise

International links

United States

(Framingham Heart Study, Massachusetts) Collaboration on investigation of role of haemostatic factors in cardiovascular disease

Selected grants

2014

  • The 'Optimise' study; Trevena L, Emery J, Dowie J, Pearson S, Rothwell P, Pignone M, Olver I, Tofler G, Barnes E; National Health and Medical Research Council (NHMRC)/Project Grants.

2001

  • Depression and risk of coronary heart disease: a prospective study of mediating haemostatic risk factors; Tennant C, Tofler G, Ward C, Berry G; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Tofler, G., O'Farrell, A., Buckley, T. (2012). Psychological Triggers for Plaque Rupture. In Paul Hjemdahl, Annika Rosengren, Andew Steptoe (Eds.), Stress and Cardiovascular Disease, (pp. 151-168). London: Springer.

Journals

  • Klempfner, R., Koifman, E., Goldenberg, I., Hamdan, A., Tofler, G., Kopel, E. (2014). The Israel Nationwide Heart Failure Survey: Sex Differences in Early and Late Mortality for Hospitalized Heart Failure Patients. Journal of Cardiac Failure, 20(3), 193-198. [More Information]
  • Wrenn, K., Mostofsky, E., Tofler, G., Muller, J., Mittleman, M. (2013). Anxiety, anger, and mortality risk among survivors of myocardial infarction. The American Journal of Medicine, 126(12), 1107-1113. [More Information]
  • McEwen, B., Morel-Kopp, M., Chen, W., Tofler, G., Ward, C. (2013). Effects of Omega-3 Polyunsaturated Fatty Acids on Platelet Function in Healthy Subjects and Subjects with Cardiovascular Disease. Seminars in Thrombosis and Hemostasis, 39(1), 25-32. [More Information]
  • Gallagher, R., Sullivan, A., Burke, R., Hales, S., Gillies, G., Cameron, J., Saliba, B., Tofler, G. (2013). Mild cognitive impairment, screening, and patient perceptions in heart failure patients. Journal of Cardiac Failure, 19(9), 641-646. [More Information]
  • Koifman, E., Kopel, E., Maor, E., Fefer, P., Matezky, S., Tofler, G., Hamdan, A., Grossman, E., Goldenberg, I., Klempfner, R. (2013). Mineralocorticoid receptor antagonist use in eligible patients following acute myocardial infarction: Real world data from the Acute Coronary Syndrome Israeli Surveys: 2004–2010. International Journal of Cardiology, 168(4), 3971-3976. [More Information]
  • Sabater-Lleal, M., Huang, J., Chasman, D., Naitza, S., Deghan, A., Johnson, A., Teumer, A., Reiner, A., Folkersen, L., Basu, S., Tofler, G., et al (2013). Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease. Circulation, 128(12), 1310-1324. [More Information]
  • Buckley, T., Tofler, G., Prigerson, H. (2013). Posttraumatic Stress Disorder as a Risk Factor for Cardiovascular Disease: A Literature Review and Proposed Mechanisms. Current Cardiovascular Risk Reports, 7(6), 506-513. [More Information]
  • Glozier, N., Tofler, G., Colquhoun, D., Bunker, S., Clarke, D., Hare, D., Hickie, I., Tatoulis, J., Thompson, D., Wilson, A., et al (2013). Psychosocial risk factors for coronary heart disease. Medical Journal of Australia, 199(3), 1-6. [More Information]
  • Mostofsky, E., Maclure, M., Tofler, G., Muller, J., Mittleman, M. (2013). Relation of outbursts of anger and risk of acute myocardial infarction. The American Journal of Cardiology, 112(3), 343-348. [More Information]
  • Colquhoun, D., Bunker, S., Clarke, D., Glozier, N., Hare, D., Hickie, I., Tatoulis, J., Thompson, D., Tofler, G., Wilson, A., et al (2013). Screening, referral and treatment for depression in patients with coronary heart disease. Medical Journal of Australia, 198(9), 483-484. [More Information]
  • Tofler, G., Spinaze, M., Shaw, E., Buckley, T. (2013). Therapy for Triggered Acute Risk Prevention in Subjects at Increased Cardiovascular Risk. The American Journal of Cardiology, 111(12), 1755-1758. [More Information]
  • Gallagher, R., Kirkness, A., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A Randomised Trial of a Weight Loss Intervention for Overweight and Obese People Diagnosed with Coronary Heart Disease and/or Type 2 Diabetes. Annals of Behavioral Medicine, 44(1), 119-128. [More Information]
  • McEwen, B., Phillips, C., Morel-Kopp, M., Yee, B., Sullivan, D., Ward, C., Tofler, G., Grunstein, R. (2012). Diurnal changes and levels of fibrin generation are not altered by continuous positive airway pressure (CPAP) in obstructive sleep apnoea (OSA). Journal of Thrombosis and Haemostasis, 108(4), 701-709. [More Information]
  • Buckley, T., Stannard, A., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2012). Effect of Early Bereavement on Heart Rate and Heart Rate Variability. The American Journal of Cardiology, 110(9), 1378-1383. [More Information]
  • Phillips, C., McEwen, B., Morel-Kopp, M., Yee, B., Sullivan, D., Ward, C., Tofler, G., Grunstein, R. (2012). Effects of continuous positive airway pressure on coagulability in obstructive sleep apnoea: a randomised, placebo-controlled crossover study. Thorax, 67(7), 639-644. [More Information]
  • Huang, J., Sabater-Lleal, M., Asselbergs, F., Tregouet, D., Shin, S., Ding, J., Baumert, J., Oudot-Mellakh, T., Folkersen, L., Johnson, A., Tofler, G., et al (2012). Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood, 120(24), 4873-4881. [More Information]
  • Buckley, T., Morel-Kopp, M., Ward, C., Bartrop, R., McKinley, S., Mihailidou, A., Spinaze, M., Chen, W., Tofler, G. (2012). Inflammatory and thrombotic changes in early bereavement: A prospective evaluation. European Journal of Preventive Cardiology, 19(5), 1145-1152. [More Information]
  • Buckley, T., Sunari, D., Marshall, A., Bartrop, R., McKinley, S., Tofler, G. (2012). Physiological correlates of bereavement and the impact of bereavement interventions. Dialogues in Clinical Neuroscience, 14(2), 129-139. [More Information]
  • Mostofsky, E., Maclure, M., Sherwood, J., Tofler, G., Muller, J., Mittleman, M. (2012). Risk of Acute Myocardial Infarction After the Death of a Significant Person in One's Life: The Determinants of Myocardial Infarction Onset Study. Circulation, 125(3), 491-496. [More Information]
  • Gallagher, R., Sullivan, A., Hales, S., Gillies, G., Burke, R., Tofler, G. (2012). Symptom patterns, duration and responses in newly diagnosed patients with heart failure. International Journal of Nursing Practice, 18(2), 133-139. [More Information]
  • Buckley, T., Soo-Hoo, S., Fenethy, J., O'Farell, A., Hansen, P., Tofler, G. (2012). The association between episodes of anger and onset of acute myocardial infarction. Heart, Lung and Circulation.
  • Robaei, D., Koe, L., Bais, R., Gould, I., Stewart, T., Tofler, G. (2011). Effect of NT-proBNP testing on diagnostic certainty in patients admitted to the emergency department with possible heart failure. Annals of Clinical Biochemistry: an international journal of biochemistry in medicine, 48(3), 212-217. [More Information]
  • Smith, N., Huffman, J., Strachan, D., Huang, J., Dehghan, A., Trompet, S., Lopez, L., Shin, S., Baumert, J., Vitart, V., Tofler, G., et al (2011). Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation, 123(17), 1864-1872. [More Information]
  • Buckley, T., Mihailidou, A., Bartrop, R., McKinley, S., Ward, C., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Haemodynamic Changes During Early Bereavement: Potential Contribution to Increased Cardiovascular Risk. Heart, Lung and Circulation, 20(2), 91-98. [More Information]
  • Faraday, N., Yanek, L., Yang, X., Mathias, R., Herrera-Galeano, J., Suktitipat, B., Qayyum, R., Johnson, A., Chen, M., Tofler, G., et al (2011). Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood, 118(12), 3367-3375. [More Information]
  • Mihailidou, A., Buckley, T., McKinley, S., Ward, C., Bartrop, R., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Increased blood pressure variability during early bereavement. Circulation (Baltimore), 124(S1), A17769.
  • Tofler, G., Spinaze, M., Buckley, T., Shaw, E. (2011). Triggered acute risk prevention: Feasibility in higher risk subjects. Heart, Lung and Circulation, 20(S2), S251.
  • Fox, C., Gona, P., Larson, M., Selhub, J., Tofler, G., Hwang, S., Meigs, J., Levy, D., Wang, T., Jacques, P., et al (2010). A Multi-Marker Approach to Predict Incident CKD and Microalbuminuria. Journal of the American Society of Nephrology, 21(12), 2143-2149. [More Information]
  • Stewart, T., Freeman, J., Stewart, J., Sullivan, A., Ward, C., Tofler, G. (2010). Anaemia in heart failure: a prospective evaluation of clinical outcome in a community population. Heart, Lung and Circulation, 19(12), 730-735. [More Information]
  • Musunuru, K., Post, W., Herzog, W., Shen, H., O'Connell, J., McArdle, P., Ryan, K., Gibson, Q., Cheng, Y., Clearfield, E., Tofler, G., et al (2010). Association of Single Nucleotide Polymorphisms on Chromosome 9p21.3 With Platelet Reactivity: A Potential Mechanism for Increased Vascular Disease. Circulation: Cardiovascular Genetics, 3(5), 445-453. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2010). Early bereavement is associated with increased heart rate and reduced heart rate variability. Circulation, 122, A14660.
  • McEwen, B., Morel-Kopp, M., Tofler, G., Ward, C. (2010). Effect of Omega-3 Fish Oil on Cardiovascular Risk in Diabetes. The Diabetes Educator, 36(4), 565-584. [More Information]
  • Johnson, A., Yanek, L., Chen, M., Faraday, N., Larson, M., Tofler, G., Lin, S., Kraja, A., Province, M., Yang, Q., et al (2010). Genome-Wide Meta-Analyses Identifies Seven Loci Associated with Platelet Aggregation in Response to Agonists. Nature Genetics, 42(7), 608-613. [More Information]
  • May, R., Tofler, G., Bartrop, R., Heinrich, P., Baird, J., Jozefiak, E., de Burgh, S. (2010). Smoking Cessation Through a Novel Behavior Modification Technique. The American Journal of Cardiology, 106(1), 44-46. [More Information]
  • Figtree, G., Thiruvallapan, N., Brereton, J., Whalley, D., Tofler, G. (2010). The effect of elevated right atrial pressure due to pulmonary emboli on detection of patent foramen ovale and potential paradoxical embolus. Journal of Cardiovascular Medicine (Hagerstown), 11(1), 61-63. [More Information]
  • Taylor, B., Tofler, G., Morel-Kopp, M., Carey, H., Carter, T., Elliott, M., Dailey, C., Villata, L., Ward, C., Woodward, M., et al (2010). The effect of initial treatment of periodontitis on systemic markers of inflammation and cardiovascular risk: a randomized controlled trial. European Journal of Oral Sciences, 118(4), 350-356. [More Information]
  • Karimi Galougahi, K., Stewart, T., Choong, C., Storey, C., Yates, M., Tofler, G. (2010). The Utility of Transoesophageal Echocardiography to Determine Management in Suspected Embolic Stroke. Internal Medicine Journal, 40(12), 813-818. [More Information]
  • Buckley, T., Mihailidou, A., Bartrop, R., Ward, C., Morel-Kopp, M., McKinley, S., Spinaze, M., Tofler, G. (2009). An evaluation of psychological and physiological determinants of cardiovascular risk in early bereavement. Heart, Lung and Circulation, 18(3), S7.
  • Dehghan, A., Yang, Q., Peters, A., Basu, S., Bis, J., Rudnicka, A., Kavousi, M., Chen, M., Baumert, J., Tofler, G., et al (2009). Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circulation: Cardiovascular Genetics, 2(2), 125-133. [More Information]
  • Lieb, W., Pencina, M., Lanier, K., Tofler, G., Levy, D., Fox, C., Wang, T., D'Agostino, R., Vasan, R. (2009). Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study. Diabetes, 58(1), 134-137. [More Information]
  • Tofler, G., Wood, A., White, I., Thompson, S., Kostis, J., Wilson, A., Wu, K., Benderly, M., Goldbourt, U., Willeit, J., et al (2009). Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies. Statistics in Medicine, 28(7), 1067-1092. [More Information]
  • Joseph, J., Pencina, M., Wang, T., Hayes, L., Tofler, G., Jacques, P., Selhub, J., Levy, D., D'Agostino, R., Benjamin, E., et al (2009). Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community. Journal of Hypertension, 27(6), 1317-1324. [More Information]
  • Mihailidou, A., Buckley, T., Spinaze, M., Roche, D., Bramwell, M., McKinley, S., Morel-Kopp, M., Ward, C., Bartrop, R., Tofler, G. (2009). Increased blood pressure load during bereavement: Potential mechanism for increased cardiovascular risk. Hypertension.
  • Tofler, G., Pennells, L., White, I., Wood, A., Kaptoge, S., Sarwar, N., Kostis, J., Wilson, A., Folsom, A., Chambless, L., et al (2009). Measures to assess the prognostic ability of the stratified Cox proportional hazards model. Statistics in Medicine, 28(3), 389-411. [More Information]
  • Lieb, W., Larson, M., Benjamin, E., Yin, X., Tofler, G., Selhub, J., Jacques, P., Wang, T., Vita, J., Levy, D., et al (2009). Multimarker approach to evaluate correlates of vascular stiffness the Framingham heart study. Circulation, 119(1), 37-43. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Bramwell, M., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Hocking, B., Tennant, C., Tofler, G., et al (2009). Prospective study of early bereavement on psychological and behavioural cardiac risk factors. Internal Medicine Journal, 39(6), 370-378. [More Information]
  • Tofler, G., Jackson, D., White, I., Kostis, J., Wilson, A., Folsom, A., Chambless, L., Benderly, M., Goldbourt, U., Willeit, J., et al (2009). Systematically missing confounders in individual participant data meta-analysis of observational cohort studies. Statistics in Medicine, 28(8), 1218-1237. [More Information]
  • Morel-Kopp, M., McLean, L., Chen, Q., Tofler, G., Tennant, C., Maddison, V., Ward, C. (2009). The association of depression with platelet activation: evidence for a treatment effect. Journal of Thrombosis and Haemostasis, 7(4), 573-581. [More Information]
  • Shaw, E., Tofler, G., Buckley, T., Bajorek, B., Ward, M. (2009). Therapy for Triggered Acute Risk Prevention: A Study of Feasibility. Heart, Lung and Circulation, 18(5), 347-352. [More Information]
  • Lieb, W., Pencina, M., Wang, T., Larson, M., Lanier, K., Benjamin, E., Levy, D., Tofler, G., Meigs, J., Newton-Cheh, C., et al (2008). Association of Parental Hypertension With Concentrations of Select Biomarkers in Nonhypertensive Offspring. Hypertension, 52(2), 381-386. [More Information]
  • Fox, K., Ford, I., Steg, P., Tendera, M., Ferrari, R., Freedman, B., Tofler, G. (2008). Ivabridine for patients with stable coronary artery disease and left-ventricular systolic function (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. The Lancet, 372(9641), 807-816. [More Information]
  • Velagaleti, R., Gona, P., Levy, D., Aragam, J., Larson, M., Tofler, G., Lieb, W., Wang, T., Benjamin, E., Vasan, R. (2008). Relations of biomarkers representing distinct biological pathways to left ventricular geometry. Circulation, 118(22), 2252-2258. [More Information]
  • Vuletic, S., Taylor, B., Tofler, G., Chait, A., Marcovina, S., Schenck, K., Albers, J. (2008). SAA and PLTP activity in plasma of periodontal patients before and after full-mouth tooth extraction. Oral Diseases, 14(6), 514-519. [More Information]
  • Buckley, T., Tofler, G. (2008). The relationship between psychological stress and cardiac disease. Not Known, , 1-2.
  • Frankel, D., Meigs, J., Massaro, J., Wilson, P., O'Donnell, C., D'Agostino, R., Tofler, G. (2008). Von Willebrand Factor, Type 2 Diabetes Mellitus, and Risk of Cardiovascular Disease. The Framingham Offspring Study. Circulation, 118(24), 2533-2539. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Goldstone, K., Ward, C., Bramwell, M., Hocking, B., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tennant, C., Tofler, G. (2007). An evaluation of psychological and behavioural factors during bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Tofler, G., Kaptoge, S., White, I., Thompson, S., Wood, A., Lewington, S., Lowe, G., Danesh, J., Kostis, J., Wilson, A., et al (2007). Associations of Plasma Fibrinogen Levels with Established Cardiovascular Disease Risk Factors, Inflammatory Markers, and Other Characteristics: Individual Participant Meta-Analysis of 154,211 Adults in 31 Prospective Studies. American Journal of Epidemiology, 166(8), 867-879.
  • Yang, Q., Kathiresan, S., Lin, J., Tofler, G., O'Donnell, C. (2007). Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. BMC Medical Genetics, 8(Supplement 1 - Article number S12), 1-11. [More Information]
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tofler, G., et al (2007). Inflammatory and thrombotic changes in bereavement in bereavement: A potential mechanism of increased cardiovascular risk. Circulation, 116(16), 844.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tennant, C., Tofler, G. (2007). Inflammatory, thrombotic and haemodynamic changes in bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Ingelsson, E., Pencina, M., Tofler, G., Benjamin, E., Lanier, K., Jacques, P., Fox, C., Meigs, J., Levy, D., Larson, M., et al (2007). Multimarker Approach to Evaluate the Incidence of the Metabolic Syndrome and Longitudinal Changes in Metabolic Risk Factors. Circulation, 116(9), 984-992. [More Information]
  • Wang, T., Gona, P., Larson, M., Levy, D., Benjamin, E., Tofler, G., Jacques, P., Meigs, J., Rifai, N., Selhub, J., et al (2007). Multiple Biomarkers and the Risk of Incident Hypertension. Hypertension, 49(3), 432-438. [More Information]
  • Aw, T., Liew, D., Tofler, G., Schneider, H., Morel-Kopp, M., Billah, B., Krum, H. (2006). Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels? Journal of Hypertension, 24(10), 1979-1984. [More Information]
  • Kathiresan, S., Gona, P., Larson, M., Vita, J., Mitchell, G., Tofler, G., Levy, D., Newton-Cheh, C., Wang, T., Benjamin, E., et al (2006). Cross-Sectional Relations of Multiple Biomarkers From Distinct Biological Pathways to Brachial Artery Endothelial Function. Circulation, 113(7), 938-945. [More Information]
  • Taylor, B., Tofler, G., Carey, H., Morel-Kopp, M., Philcox, S., Carter, T., Elliott, M., Kull, A., Ward, C., Schenck, K. (2006). Full-mouth tooth extraction lowers systemic inflammatory and thrombotic markers of cardiovascular risk. Journal of Dental Research, 85(1), 74-78. [More Information]
  • Meigs, J., O'Donnell, C., Tofler, G., Benjamin, E., Fox, C., Lipinska, I., Nathan, D., Sullivan, L., D'Agostino, R., Wilson, P. (2006). Hemostatic markers of endothelial dysfunction and risk of incident type 2 Diabetes: The Framingham Offspring Study. Diabetes, 55(2), 530-537. [More Information]
  • Wang, T., Gona, P., Larson, M., Tofler, G., Levy, D., Newton-Cheh, C., Jacques, P., Rifai, N., Selhub, J., Robins, S., et al (2006). Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death. New England Journal of Medicine, 355(25), 2631. [More Information]
  • Meigs, J., Dupuis, J., Liu, C., O'Donnell, C., Fox, C., Kathiresan, S., Gabriel, S., Larson, M., Yang, Q., Herbert, A., Tofler, G., et al (2006). PAI-1 Gene 4G/5G Polymorphism and Risk of Type 2 Diabetes in a Population-based Sample. Obesity, 14(5), 753-758. [More Information]
  • Wood, A., White, I., Thompson, S., Lewington, S., Danesh, J., Kostis, J., Wilson, A., Folsom, A., Wu, K., Tofler, G., et al (2006). Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27 247 adults in 15 prospective studies. International Journal of Epidemiology, 35(6), 1570-1578. [More Information]
  • Leow, N., Morel-Kopp, M., Woodward, M., Chen, Q., Tofler, G., Taylor, B. (2006). The relationship between cotinine and periodontal disease. Annals of the Royal Australasian College of Dental Surgeons, 18(September 2006), 51-52. [More Information]
  • Tofler, G., Muller, J. (2006). Triggering of acute cardiovascular disease and potential preventive strategies. Circulation, 114(17), 1863-1872. [More Information]
  • Mukamal, K., Massaro, J., Ault, K., Mittleman, M., Sutherland, P., Lipinska, I., Levy, D., D'Agostino, R., Tofler, G. (2005). Alcohol consumption and platelet activation and aggregation among women and men: the Framingham Offspring Study. Alcoholism: Clinical and Experimental Research, 29(10), 1906-1912. [More Information]
  • Kathiresan, S., Gabriel, S., Yang, Q., Lochner, A., Larson, M., Levy, D., Tofler, G., Hirschhorn, J., O'Donnell, C. (2005). Comprehensive survey of common genetic variation at the plasminogen activator inhibitor-1 locus and relations to circulating plasminogen activator inhibitor-1 levels. Circulation, 112(12), 1728-1735. [More Information]
  • Halcomb, E., Davidson, P., Daly, J., Griffiths, R., Yallop, J., Tofler, G. (2005). Nursing in Australian general practice: directions and perspectives. Australian Health Review, 29(2), 156-166. [More Information]
  • Tofler, G., Massaro, J., Levy, D., Mittleman, M., Sutherland, P., Lipinska, I., Muller, J., D'Agostino, R. (2005). Relation of the prothrombotic state to increasing age (from the Framingham Offspring Study). The American Journal of Cardiology, 96(9), 1280-3. [More Information]
  • Fox, C., Larson, M., Corey, D., Feng, D., Lindpaintner, K., Polak, J., Wolf, P., D'Agostino, R., Tofler, G., O'Donnell, C. (2004). Absence Of Association Between Polymorphisms In The Hemostatic Factor Pathway Genes And Carotid Intimal Medial Thickness: The Framingham Heart Study. Stroke: a journal of cerebral circulation, 35(3), e65-e67.
  • Rosito, G., D'Agostino, R., Massaro, J., Lipinska, I., Mittleman, M., Sutherland, P., Wilson, P., Levy, D., Muller, J., Tofler, G. (2004). Association Between Obesity And A Prothrombotic State: The Framingham Offspring Study. Thrombosis and Haemostasis, 91(4), 683-689.
  • Halcomb, E., Davidson, P., Daly, J., Yallop, J., Tofler, G. (2004). Australian Nurses In General Practice Based Heart Failure Management: Implications For Innovative Collaborative Practice. European Journal of Cardiovascular Nursing, 3(2), 135-147.
  • Phillips, S., Marton, R., Tofler, G. (2004). Barriers To Diagnosing And Managing Heart Failure In Primary Care. Medical Journal of Australia, 181(2), 78-81.
  • Whang, W., Mittleman, M., Rich, D., Wang, P., Ruskin, J., Tofler, G., Muller, J., Albert, C. (2004). Heart Failure And The Risk Of Shocks In Patients With Implantable Cardioverter Defibrillators: Results From The Triggers Of Ventricular Arrhythmias (Tova) Study. Circulation, 109(11), 1386-1391.
  • Phillips, S., Davies, J., Tofler, G. (2004). NICS Heart Failure Forum: improving outcomes in chronic care. Medical Journal of Australia, 181(6), 297-299.
  • Tofler, G., D'Agostino, R., Jacques, P., Bostom, A., Wilson, P., Lipinska, I., Mittleman, M., Selhub, J. (2002). Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk. Thrombosis and Haemostasis, 88(5), 799-804.
  • Seigel, A., Mendelson, J., Sholar, M., McDonald, J., Lewandrowski, K., Lewandrowski, E., Lipinska, I., Ridker, P., Tofler, G. (2002). Effect of Cocaine Usage on C-Reactive Protein, von Willebrand Factor, and Fibrinogen. The American Journal of Cardiology, 89(9), 1133-1135.
  • Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, , 473-475.
  • D'Elia, J., Weinrauch, L., Gleason, R., Lipinska, I., Keough, J., Pendse, S., Roshan, B., Lee, A., Tofler, G. (2001). Fibrinogen and factor VII levels improve with glycemic control in patients with type 1 diabetes mellitus who have microvascular complications. Archives of Internal Medicine, 161, 98-101.
  • O'Donnell, C., Larson, M., Feng, D., Sutherland, P., Lindpaintner, K., Myers, R., D'Agostino, R., Levy, D., Tofler, G. (2001). Genetic and environmental contributions to platelet. Circulation, 103, 3051-3056.

Conferences

  • Sullivan, A., Burke, R., Gillies, G., Hales, S., Gallagher, R., Tofler, G. (2013). Social Support and health related quality of life in heart failure patients enrolled in a home visit program. 7th Annual Conference of the Australasian Cardiovascular Nursing College 2013, Auckland, New Zealand.
  • Gallagher, R., Kirkness, A., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A Randomised trial of a weight loss intervention for overweight and obese people diagnosed with coronary heart disease and/or type 2 diabetes. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Kirkness, A., Gallagher, R., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A randomised trial of a Weight Loss Intervention Supplement to Cardiac Rehabilitation and Diabetes Education for Overweight and obese people. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Burke, R., Gillies, G., Hales, S., Sullivan, A., Tofler, G., Gallagher, R. (2012). Cognitive Impairment in Heart Failure Patients. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Lin, R., Tofler, G., Spinaze, M., Dennis, C., Clifton-Bligh, R., Nojoumian, H., Gallagher, R. (2012). Patient-Directed Discharge Letter (PADDLE) - A Simple and brief intervention to improve patient knowledge and understanding at time of hospital discharge. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Sullivan, A., Burke, R., Gillies, G., Hales, S., Gallagher, R., Tofler, G. (2012). Prevalence of moderate cognitive impairment in heart failure patients without diagnosed dementia. 6th Annual Conference of the Australasian Cardiovascular Nursing College (ACNC) 2012, Sydney, NSW, Australia.
  • Aslani, P., Krass, I., Bajorek, B., Thistlethwaite, J., Bunker, J., Tofler, G. (2009). Exploring the barriers to achieving quality use of medicines in cardiovascular health. Australasian Pharmaceutical Science Association (APSA) Annual Conference (2009) Aus-CRS Symposium, Mount Waverley, Melbourne, Australia: Australasian Pharmaceutical Science Association.
  • Sullivan, A., Hales, S., Gillies, G., Gallagher, R., Baker,, V., Tofler, G. (2008). Do Heart Failure Patients Practice self-managements? 56th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2008, Adelaide, South Australia, Australia.
  • Gallagher, R., Sullivan, A., Hales, S., Gillies, G., Baker,, V., Tofler, G. (2008). The nature and duration of worsening heart failure symptoms and contacts made prior to hospitalisation. 56th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2008, Adelaide, South Australia, Australia. [More Information]

2014

  • Klempfner, R., Koifman, E., Goldenberg, I., Hamdan, A., Tofler, G., Kopel, E. (2014). The Israel Nationwide Heart Failure Survey: Sex Differences in Early and Late Mortality for Hospitalized Heart Failure Patients. Journal of Cardiac Failure, 20(3), 193-198. [More Information]

2013

  • Wrenn, K., Mostofsky, E., Tofler, G., Muller, J., Mittleman, M. (2013). Anxiety, anger, and mortality risk among survivors of myocardial infarction. The American Journal of Medicine, 126(12), 1107-1113. [More Information]
  • McEwen, B., Morel-Kopp, M., Chen, W., Tofler, G., Ward, C. (2013). Effects of Omega-3 Polyunsaturated Fatty Acids on Platelet Function in Healthy Subjects and Subjects with Cardiovascular Disease. Seminars in Thrombosis and Hemostasis, 39(1), 25-32. [More Information]
  • Gallagher, R., Sullivan, A., Burke, R., Hales, S., Gillies, G., Cameron, J., Saliba, B., Tofler, G. (2013). Mild cognitive impairment, screening, and patient perceptions in heart failure patients. Journal of Cardiac Failure, 19(9), 641-646. [More Information]
  • Koifman, E., Kopel, E., Maor, E., Fefer, P., Matezky, S., Tofler, G., Hamdan, A., Grossman, E., Goldenberg, I., Klempfner, R. (2013). Mineralocorticoid receptor antagonist use in eligible patients following acute myocardial infarction: Real world data from the Acute Coronary Syndrome Israeli Surveys: 2004–2010. International Journal of Cardiology, 168(4), 3971-3976. [More Information]
  • Sabater-Lleal, M., Huang, J., Chasman, D., Naitza, S., Deghan, A., Johnson, A., Teumer, A., Reiner, A., Folkersen, L., Basu, S., Tofler, G., et al (2013). Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease. Circulation, 128(12), 1310-1324. [More Information]
  • Buckley, T., Tofler, G., Prigerson, H. (2013). Posttraumatic Stress Disorder as a Risk Factor for Cardiovascular Disease: A Literature Review and Proposed Mechanisms. Current Cardiovascular Risk Reports, 7(6), 506-513. [More Information]
  • Glozier, N., Tofler, G., Colquhoun, D., Bunker, S., Clarke, D., Hare, D., Hickie, I., Tatoulis, J., Thompson, D., Wilson, A., et al (2013). Psychosocial risk factors for coronary heart disease. Medical Journal of Australia, 199(3), 1-6. [More Information]
  • Mostofsky, E., Maclure, M., Tofler, G., Muller, J., Mittleman, M. (2013). Relation of outbursts of anger and risk of acute myocardial infarction. The American Journal of Cardiology, 112(3), 343-348. [More Information]
  • Colquhoun, D., Bunker, S., Clarke, D., Glozier, N., Hare, D., Hickie, I., Tatoulis, J., Thompson, D., Tofler, G., Wilson, A., et al (2013). Screening, referral and treatment for depression in patients with coronary heart disease. Medical Journal of Australia, 198(9), 483-484. [More Information]
  • Sullivan, A., Burke, R., Gillies, G., Hales, S., Gallagher, R., Tofler, G. (2013). Social Support and health related quality of life in heart failure patients enrolled in a home visit program. 7th Annual Conference of the Australasian Cardiovascular Nursing College 2013, Auckland, New Zealand.
  • Tofler, G., Spinaze, M., Shaw, E., Buckley, T. (2013). Therapy for Triggered Acute Risk Prevention in Subjects at Increased Cardiovascular Risk. The American Journal of Cardiology, 111(12), 1755-1758. [More Information]

2012

  • Gallagher, R., Kirkness, A., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A Randomised Trial of a Weight Loss Intervention for Overweight and Obese People Diagnosed with Coronary Heart Disease and/or Type 2 Diabetes. Annals of Behavioral Medicine, 44(1), 119-128. [More Information]
  • Gallagher, R., Kirkness, A., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A Randomised trial of a weight loss intervention for overweight and obese people diagnosed with coronary heart disease and/or type 2 diabetes. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Kirkness, A., Gallagher, R., Zelestis, E., Hollams, D., Kneale, C., Armari, E., Bennett, T., Daly, J., Tofler, G. (2012). A randomised trial of a Weight Loss Intervention Supplement to Cardiac Rehabilitation and Diabetes Education for Overweight and obese people. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Burke, R., Gillies, G., Hales, S., Sullivan, A., Tofler, G., Gallagher, R. (2012). Cognitive Impairment in Heart Failure Patients. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • McEwen, B., Phillips, C., Morel-Kopp, M., Yee, B., Sullivan, D., Ward, C., Tofler, G., Grunstein, R. (2012). Diurnal changes and levels of fibrin generation are not altered by continuous positive airway pressure (CPAP) in obstructive sleep apnoea (OSA). Journal of Thrombosis and Haemostasis, 108(4), 701-709. [More Information]
  • Buckley, T., Stannard, A., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2012). Effect of Early Bereavement on Heart Rate and Heart Rate Variability. The American Journal of Cardiology, 110(9), 1378-1383. [More Information]
  • Phillips, C., McEwen, B., Morel-Kopp, M., Yee, B., Sullivan, D., Ward, C., Tofler, G., Grunstein, R. (2012). Effects of continuous positive airway pressure on coagulability in obstructive sleep apnoea: a randomised, placebo-controlled crossover study. Thorax, 67(7), 639-644. [More Information]
  • Huang, J., Sabater-Lleal, M., Asselbergs, F., Tregouet, D., Shin, S., Ding, J., Baumert, J., Oudot-Mellakh, T., Folkersen, L., Johnson, A., Tofler, G., et al (2012). Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood, 120(24), 4873-4881. [More Information]
  • Buckley, T., Morel-Kopp, M., Ward, C., Bartrop, R., McKinley, S., Mihailidou, A., Spinaze, M., Chen, W., Tofler, G. (2012). Inflammatory and thrombotic changes in early bereavement: A prospective evaluation. European Journal of Preventive Cardiology, 19(5), 1145-1152. [More Information]
  • Lin, R., Tofler, G., Spinaze, M., Dennis, C., Clifton-Bligh, R., Nojoumian, H., Gallagher, R. (2012). Patient-Directed Discharge Letter (PADDLE) - A Simple and brief intervention to improve patient knowledge and understanding at time of hospital discharge. 60th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2012, Brisbane, Queensland, Australia. [More Information]
  • Buckley, T., Sunari, D., Marshall, A., Bartrop, R., McKinley, S., Tofler, G. (2012). Physiological correlates of bereavement and the impact of bereavement interventions. Dialogues in Clinical Neuroscience, 14(2), 129-139. [More Information]
  • Sullivan, A., Burke, R., Gillies, G., Hales, S., Gallagher, R., Tofler, G. (2012). Prevalence of moderate cognitive impairment in heart failure patients without diagnosed dementia. 6th Annual Conference of the Australasian Cardiovascular Nursing College (ACNC) 2012, Sydney, NSW, Australia.
  • Tofler, G., O'Farrell, A., Buckley, T. (2012). Psychological Triggers for Plaque Rupture. In Paul Hjemdahl, Annika Rosengren, Andew Steptoe (Eds.), Stress and Cardiovascular Disease, (pp. 151-168). London: Springer.
  • Mostofsky, E., Maclure, M., Sherwood, J., Tofler, G., Muller, J., Mittleman, M. (2012). Risk of Acute Myocardial Infarction After the Death of a Significant Person in One's Life: The Determinants of Myocardial Infarction Onset Study. Circulation, 125(3), 491-496. [More Information]
  • Gallagher, R., Sullivan, A., Hales, S., Gillies, G., Burke, R., Tofler, G. (2012). Symptom patterns, duration and responses in newly diagnosed patients with heart failure. International Journal of Nursing Practice, 18(2), 133-139. [More Information]
  • Buckley, T., Soo-Hoo, S., Fenethy, J., O'Farell, A., Hansen, P., Tofler, G. (2012). The association between episodes of anger and onset of acute myocardial infarction. Heart, Lung and Circulation.

2011

  • Robaei, D., Koe, L., Bais, R., Gould, I., Stewart, T., Tofler, G. (2011). Effect of NT-proBNP testing on diagnostic certainty in patients admitted to the emergency department with possible heart failure. Annals of Clinical Biochemistry: an international journal of biochemistry in medicine, 48(3), 212-217. [More Information]
  • Smith, N., Huffman, J., Strachan, D., Huang, J., Dehghan, A., Trompet, S., Lopez, L., Shin, S., Baumert, J., Vitart, V., Tofler, G., et al (2011). Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation, 123(17), 1864-1872. [More Information]
  • Buckley, T., Mihailidou, A., Bartrop, R., McKinley, S., Ward, C., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Haemodynamic Changes During Early Bereavement: Potential Contribution to Increased Cardiovascular Risk. Heart, Lung and Circulation, 20(2), 91-98. [More Information]
  • Faraday, N., Yanek, L., Yang, X., Mathias, R., Herrera-Galeano, J., Suktitipat, B., Qayyum, R., Johnson, A., Chen, M., Tofler, G., et al (2011). Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood, 118(12), 3367-3375. [More Information]
  • Mihailidou, A., Buckley, T., McKinley, S., Ward, C., Bartrop, R., Morel-Kopp, M., Spinaze, M., Tofler, G. (2011). Increased blood pressure variability during early bereavement. Circulation (Baltimore), 124(S1), A17769.
  • Tofler, G., Spinaze, M., Buckley, T., Shaw, E. (2011). Triggered acute risk prevention: Feasibility in higher risk subjects. Heart, Lung and Circulation, 20(S2), S251.

2010

  • Fox, C., Gona, P., Larson, M., Selhub, J., Tofler, G., Hwang, S., Meigs, J., Levy, D., Wang, T., Jacques, P., et al (2010). A Multi-Marker Approach to Predict Incident CKD and Microalbuminuria. Journal of the American Society of Nephrology, 21(12), 2143-2149. [More Information]
  • Stewart, T., Freeman, J., Stewart, J., Sullivan, A., Ward, C., Tofler, G. (2010). Anaemia in heart failure: a prospective evaluation of clinical outcome in a community population. Heart, Lung and Circulation, 19(12), 730-735. [More Information]
  • Musunuru, K., Post, W., Herzog, W., Shen, H., O'Connell, J., McArdle, P., Ryan, K., Gibson, Q., Cheng, Y., Clearfield, E., Tofler, G., et al (2010). Association of Single Nucleotide Polymorphisms on Chromosome 9p21.3 With Platelet Reactivity: A Potential Mechanism for Increased Vascular Disease. Circulation: Cardiovascular Genetics, 3(5), 445-453. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tofler, G. (2010). Early bereavement is associated with increased heart rate and reduced heart rate variability. Circulation, 122, A14660.
  • McEwen, B., Morel-Kopp, M., Tofler, G., Ward, C. (2010). Effect of Omega-3 Fish Oil on Cardiovascular Risk in Diabetes. The Diabetes Educator, 36(4), 565-584. [More Information]
  • Johnson, A., Yanek, L., Chen, M., Faraday, N., Larson, M., Tofler, G., Lin, S., Kraja, A., Province, M., Yang, Q., et al (2010). Genome-Wide Meta-Analyses Identifies Seven Loci Associated with Platelet Aggregation in Response to Agonists. Nature Genetics, 42(7), 608-613. [More Information]
  • May, R., Tofler, G., Bartrop, R., Heinrich, P., Baird, J., Jozefiak, E., de Burgh, S. (2010). Smoking Cessation Through a Novel Behavior Modification Technique. The American Journal of Cardiology, 106(1), 44-46. [More Information]
  • Figtree, G., Thiruvallapan, N., Brereton, J., Whalley, D., Tofler, G. (2010). The effect of elevated right atrial pressure due to pulmonary emboli on detection of patent foramen ovale and potential paradoxical embolus. Journal of Cardiovascular Medicine (Hagerstown), 11(1), 61-63. [More Information]
  • Taylor, B., Tofler, G., Morel-Kopp, M., Carey, H., Carter, T., Elliott, M., Dailey, C., Villata, L., Ward, C., Woodward, M., et al (2010). The effect of initial treatment of periodontitis on systemic markers of inflammation and cardiovascular risk: a randomized controlled trial. European Journal of Oral Sciences, 118(4), 350-356. [More Information]
  • Karimi Galougahi, K., Stewart, T., Choong, C., Storey, C., Yates, M., Tofler, G. (2010). The Utility of Transoesophageal Echocardiography to Determine Management in Suspected Embolic Stroke. Internal Medicine Journal, 40(12), 813-818. [More Information]

2009

  • Buckley, T., Mihailidou, A., Bartrop, R., Ward, C., Morel-Kopp, M., McKinley, S., Spinaze, M., Tofler, G. (2009). An evaluation of psychological and physiological determinants of cardiovascular risk in early bereavement. Heart, Lung and Circulation, 18(3), S7.
  • Dehghan, A., Yang, Q., Peters, A., Basu, S., Bis, J., Rudnicka, A., Kavousi, M., Chen, M., Baumert, J., Tofler, G., et al (2009). Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circulation: Cardiovascular Genetics, 2(2), 125-133. [More Information]
  • Lieb, W., Pencina, M., Lanier, K., Tofler, G., Levy, D., Fox, C., Wang, T., D'Agostino, R., Vasan, R. (2009). Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study. Diabetes, 58(1), 134-137. [More Information]
  • Tofler, G., Wood, A., White, I., Thompson, S., Kostis, J., Wilson, A., Wu, K., Benderly, M., Goldbourt, U., Willeit, J., et al (2009). Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies. Statistics in Medicine, 28(7), 1067-1092. [More Information]
  • Joseph, J., Pencina, M., Wang, T., Hayes, L., Tofler, G., Jacques, P., Selhub, J., Levy, D., D'Agostino, R., Benjamin, E., et al (2009). Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community. Journal of Hypertension, 27(6), 1317-1324. [More Information]
  • Aslani, P., Krass, I., Bajorek, B., Thistlethwaite, J., Bunker, J., Tofler, G. (2009). Exploring the barriers to achieving quality use of medicines in cardiovascular health. Australasian Pharmaceutical Science Association (APSA) Annual Conference (2009) Aus-CRS Symposium, Mount Waverley, Melbourne, Australia: Australasian Pharmaceutical Science Association.
  • Mihailidou, A., Buckley, T., Spinaze, M., Roche, D., Bramwell, M., McKinley, S., Morel-Kopp, M., Ward, C., Bartrop, R., Tofler, G. (2009). Increased blood pressure load during bereavement: Potential mechanism for increased cardiovascular risk. Hypertension.
  • Tofler, G., Pennells, L., White, I., Wood, A., Kaptoge, S., Sarwar, N., Kostis, J., Wilson, A., Folsom, A., Chambless, L., et al (2009). Measures to assess the prognostic ability of the stratified Cox proportional hazards model. Statistics in Medicine, 28(3), 389-411. [More Information]
  • Lieb, W., Larson, M., Benjamin, E., Yin, X., Tofler, G., Selhub, J., Jacques, P., Wang, T., Vita, J., Levy, D., et al (2009). Multimarker approach to evaluate correlates of vascular stiffness the Framingham heart study. Circulation, 119(1), 37-43. [More Information]
  • Buckley, T., Bartrop, R., McKinley, S., Ward, C., Bramwell, M., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Hocking, B., Tennant, C., Tofler, G., et al (2009). Prospective study of early bereavement on psychological and behavioural cardiac risk factors. Internal Medicine Journal, 39(6), 370-378. [More Information]
  • Tofler, G., Jackson, D., White, I., Kostis, J., Wilson, A., Folsom, A., Chambless, L., Benderly, M., Goldbourt, U., Willeit, J., et al (2009). Systematically missing confounders in individual participant data meta-analysis of observational cohort studies. Statistics in Medicine, 28(8), 1218-1237. [More Information]
  • Morel-Kopp, M., McLean, L., Chen, Q., Tofler, G., Tennant, C., Maddison, V., Ward, C. (2009). The association of depression with platelet activation: evidence for a treatment effect. Journal of Thrombosis and Haemostasis, 7(4), 573-581. [More Information]
  • Shaw, E., Tofler, G., Buckley, T., Bajorek, B., Ward, M. (2009). Therapy for Triggered Acute Risk Prevention: A Study of Feasibility. Heart, Lung and Circulation, 18(5), 347-352. [More Information]

2008

  • Lieb, W., Pencina, M., Wang, T., Larson, M., Lanier, K., Benjamin, E., Levy, D., Tofler, G., Meigs, J., Newton-Cheh, C., et al (2008). Association of Parental Hypertension With Concentrations of Select Biomarkers in Nonhypertensive Offspring. Hypertension, 52(2), 381-386. [More Information]
  • Sullivan, A., Hales, S., Gillies, G., Gallagher, R., Baker,, V., Tofler, G. (2008). Do Heart Failure Patients Practice self-managements? 56th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2008, Adelaide, South Australia, Australia.
  • Fox, K., Ford, I., Steg, P., Tendera, M., Ferrari, R., Freedman, B., Tofler, G. (2008). Ivabridine for patients with stable coronary artery disease and left-ventricular systolic function (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. The Lancet, 372(9641), 807-816. [More Information]
  • Velagaleti, R., Gona, P., Levy, D., Aragam, J., Larson, M., Tofler, G., Lieb, W., Wang, T., Benjamin, E., Vasan, R. (2008). Relations of biomarkers representing distinct biological pathways to left ventricular geometry. Circulation, 118(22), 2252-2258. [More Information]
  • Vuletic, S., Taylor, B., Tofler, G., Chait, A., Marcovina, S., Schenck, K., Albers, J. (2008). SAA and PLTP activity in plasma of periodontal patients before and after full-mouth tooth extraction. Oral Diseases, 14(6), 514-519. [More Information]
  • Gallagher, R., Sullivan, A., Hales, S., Gillies, G., Baker,, V., Tofler, G. (2008). The nature and duration of worsening heart failure symptoms and contacts made prior to hospitalisation. 56th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ) 2008, Adelaide, South Australia, Australia. [More Information]
  • Buckley, T., Tofler, G. (2008). The relationship between psychological stress and cardiac disease. Not Known, , 1-2.
  • Frankel, D., Meigs, J., Massaro, J., Wilson, P., O'Donnell, C., D'Agostino, R., Tofler, G. (2008). Von Willebrand Factor, Type 2 Diabetes Mellitus, and Risk of Cardiovascular Disease. The Framingham Offspring Study. Circulation, 118(24), 2533-2539. [More Information]

2007

  • Buckley, T., Bartrop, R., McKinley, S., Goldstone, K., Ward, C., Bramwell, M., Hocking, B., Roche, D., Mihailidou, A., Morel-Kopp, M., Spinaze, M., Tennant, C., Tofler, G. (2007). An evaluation of psychological and behavioural factors during bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Tofler, G., Kaptoge, S., White, I., Thompson, S., Wood, A., Lewington, S., Lowe, G., Danesh, J., Kostis, J., Wilson, A., et al (2007). Associations of Plasma Fibrinogen Levels with Established Cardiovascular Disease Risk Factors, Inflammatory Markers, and Other Characteristics: Individual Participant Meta-Analysis of 154,211 Adults in 31 Prospective Studies. American Journal of Epidemiology, 166(8), 867-879.
  • Yang, Q., Kathiresan, S., Lin, J., Tofler, G., O'Donnell, C. (2007). Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. BMC Medical Genetics, 8(Supplement 1 - Article number S12), 1-11. [More Information]
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tofler, G., et al (2007). Inflammatory and thrombotic changes in bereavement in bereavement: A potential mechanism of increased cardiovascular risk. Circulation, 116(16), 844.
  • Buckley, T., Morel-Kopp, M., Bartrop, R., McKinley, S., Ward, C., Mihailidou, A., Goldstone, K., Bramwell, M., Hocking, B., Roche, D., Spinaze, M., Tennant, C., Tofler, G. (2007). Inflammatory, thrombotic and haemodynamic changes in bereavement. Heart, Lung and Circulation, 16(S1), S201.
  • Ingelsson, E., Pencina, M., Tofler, G., Benjamin, E., Lanier, K., Jacques, P., Fox, C., Meigs, J., Levy, D., Larson, M., et al (2007). Multimarker Approach to Evaluate the Incidence of the Metabolic Syndrome and Longitudinal Changes in Metabolic Risk Factors. Circulation, 116(9), 984-992. [More Information]
  • Wang, T., Gona, P., Larson, M., Levy, D., Benjamin, E., Tofler, G., Jacques, P., Meigs, J., Rifai, N., Selhub, J., et al (2007). Multiple Biomarkers and the Risk of Incident Hypertension. Hypertension, 49(3), 432-438. [More Information]

2006

  • Aw, T., Liew, D., Tofler, G., Schneider, H., Morel-Kopp, M., Billah, B., Krum, H. (2006). Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels? Journal of Hypertension, 24(10), 1979-1984. [More Information]
  • Kathiresan, S., Gona, P., Larson, M., Vita, J., Mitchell, G., Tofler, G., Levy, D., Newton-Cheh, C., Wang, T., Benjamin, E., et al (2006). Cross-Sectional Relations of Multiple Biomarkers From Distinct Biological Pathways to Brachial Artery Endothelial Function. Circulation, 113(7), 938-945. [More Information]
  • Taylor, B., Tofler, G., Carey, H., Morel-Kopp, M., Philcox, S., Carter, T., Elliott, M., Kull, A., Ward, C., Schenck, K. (2006). Full-mouth tooth extraction lowers systemic inflammatory and thrombotic markers of cardiovascular risk. Journal of Dental Research, 85(1), 74-78. [More Information]
  • Meigs, J., O'Donnell, C., Tofler, G., Benjamin, E., Fox, C., Lipinska, I., Nathan, D., Sullivan, L., D'Agostino, R., Wilson, P. (2006). Hemostatic markers of endothelial dysfunction and risk of incident type 2 Diabetes: The Framingham Offspring Study. Diabetes, 55(2), 530-537. [More Information]
  • Wang, T., Gona, P., Larson, M., Tofler, G., Levy, D., Newton-Cheh, C., Jacques, P., Rifai, N., Selhub, J., Robins, S., et al (2006). Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death. New England Journal of Medicine, 355(25), 2631. [More Information]
  • Meigs, J., Dupuis, J., Liu, C., O'Donnell, C., Fox, C., Kathiresan, S., Gabriel, S., Larson, M., Yang, Q., Herbert, A., Tofler, G., et al (2006). PAI-1 Gene 4G/5G Polymorphism and Risk of Type 2 Diabetes in a Population-based Sample. Obesity, 14(5), 753-758. [More Information]
  • Wood, A., White, I., Thompson, S., Lewington, S., Danesh, J., Kostis, J., Wilson, A., Folsom, A., Wu, K., Tofler, G., et al (2006). Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27 247 adults in 15 prospective studies. International Journal of Epidemiology, 35(6), 1570-1578. [More Information]
  • Leow, N., Morel-Kopp, M., Woodward, M., Chen, Q., Tofler, G., Taylor, B. (2006). The relationship between cotinine and periodontal disease. Annals of the Royal Australasian College of Dental Surgeons, 18(September 2006), 51-52. [More Information]
  • Tofler, G., Muller, J. (2006). Triggering of acute cardiovascular disease and potential preventive strategies. Circulation, 114(17), 1863-1872. [More Information]

2005

  • Mukamal, K., Massaro, J., Ault, K., Mittleman, M., Sutherland, P., Lipinska, I., Levy, D., D'Agostino, R., Tofler, G. (2005). Alcohol consumption and platelet activation and aggregation among women and men: the Framingham Offspring Study. Alcoholism: Clinical and Experimental Research, 29(10), 1906-1912. [More Information]
  • Kathiresan, S., Gabriel, S., Yang, Q., Lochner, A., Larson, M., Levy, D., Tofler, G., Hirschhorn, J., O'Donnell, C. (2005). Comprehensive survey of common genetic variation at the plasminogen activator inhibitor-1 locus and relations to circulating plasminogen activator inhibitor-1 levels. Circulation, 112(12), 1728-1735. [More Information]
  • Halcomb, E., Davidson, P., Daly, J., Griffiths, R., Yallop, J., Tofler, G. (2005). Nursing in Australian general practice: directions and perspectives. Australian Health Review, 29(2), 156-166. [More Information]
  • Tofler, G., Massaro, J., Levy, D., Mittleman, M., Sutherland, P., Lipinska, I., Muller, J., D'Agostino, R. (2005). Relation of the prothrombotic state to increasing age (from the Framingham Offspring Study). The American Journal of Cardiology, 96(9), 1280-3. [More Information]

2004

  • Fox, C., Larson, M., Corey, D., Feng, D., Lindpaintner, K., Polak, J., Wolf, P., D'Agostino, R., Tofler, G., O'Donnell, C. (2004). Absence Of Association Between Polymorphisms In The Hemostatic Factor Pathway Genes And Carotid Intimal Medial Thickness: The Framingham Heart Study. Stroke: a journal of cerebral circulation, 35(3), e65-e67.
  • Rosito, G., D'Agostino, R., Massaro, J., Lipinska, I., Mittleman, M., Sutherland, P., Wilson, P., Levy, D., Muller, J., Tofler, G. (2004). Association Between Obesity And A Prothrombotic State: The Framingham Offspring Study. Thrombosis and Haemostasis, 91(4), 683-689.
  • Halcomb, E., Davidson, P., Daly, J., Yallop, J., Tofler, G. (2004). Australian Nurses In General Practice Based Heart Failure Management: Implications For Innovative Collaborative Practice. European Journal of Cardiovascular Nursing, 3(2), 135-147.
  • Phillips, S., Marton, R., Tofler, G. (2004). Barriers To Diagnosing And Managing Heart Failure In Primary Care. Medical Journal of Australia, 181(2), 78-81.
  • Whang, W., Mittleman, M., Rich, D., Wang, P., Ruskin, J., Tofler, G., Muller, J., Albert, C. (2004). Heart Failure And The Risk Of Shocks In Patients With Implantable Cardioverter Defibrillators: Results From The Triggers Of Ventricular Arrhythmias (Tova) Study. Circulation, 109(11), 1386-1391.
  • Phillips, S., Davies, J., Tofler, G. (2004). NICS Heart Failure Forum: improving outcomes in chronic care. Medical Journal of Australia, 181(6), 297-299.

2002

  • Tofler, G., D'Agostino, R., Jacques, P., Bostom, A., Wilson, P., Lipinska, I., Mittleman, M., Selhub, J. (2002). Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk. Thrombosis and Haemostasis, 88(5), 799-804.
  • Seigel, A., Mendelson, J., Sholar, M., McDonald, J., Lewandrowski, K., Lewandrowski, E., Lipinska, I., Ridker, P., Tofler, G. (2002). Effect of Cocaine Usage on C-Reactive Protein, von Willebrand Factor, and Fibrinogen. The American Journal of Cardiology, 89(9), 1133-1135.
  • Freedman, B., Brieger, D., Celermajer, D., Chalmers, J., Tofler, G., Campbell, T., Feneley, M., Marwick, T., Muller, D., Tonkin, A. (2002). Global cardiology comes to Australia: 14th World Congress of Cardiology, Sydney, 5-9 May 2002. Medical Journal of Australia, , 473-475.

2001

  • D'Elia, J., Weinrauch, L., Gleason, R., Lipinska, I., Keough, J., Pendse, S., Roshan, B., Lee, A., Tofler, G. (2001). Fibrinogen and factor VII levels improve with glycemic control in patients with type 1 diabetes mellitus who have microvascular complications. Archives of Internal Medicine, 161, 98-101.
  • O'Donnell, C., Larson, M., Feng, D., Sutherland, P., Lindpaintner, K., Myers, R., D'Agostino, R., Levy, D., Tofler, G. (2001). Genetic and environmental contributions to platelet. Circulation, 103, 3051-3056.

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