Associate Professor Georgina Clark

Senior Research Fellow
ANZAC Research Institute, Concord Clinical School

Telephone +61 2 9767 9896
Fax +61 2 9767 9101

Map

Current research students

Project title Research student
CD300f as a novel therapeutic antibody target in Acute Myeloid Leukaemia Robin Edward GASIOROWSKI

Selected grants

2016

  • Development of a New Specific Immunosuppressive Monoclonal Antibody to Advance Transplantation; Hart D, Hogarth P, Gray P, Clark G, Fazekas de St Groth B, Larsen S, Gottlieb D, Alexander S, Hennessy A; National Health and Medical Research Council (NHMRC)/Development Grants.

2013

  • IVIS Lumina II in vivo Imaging System; Seibel M, Handelsman D, Le Couteur D, Hart D, Nicholson G, Freedman B, Kritharides L, Jessup W, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, McMahon A, Simanainen U, Kockx M, Speranza T, Zheng Y; DVC Research/Equipment Grant.
  • Automacs Pro Seperator; Hart D, Handelsman D, Le Couteur D, Nicholson G, Kritharides L, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, Simanainen U, Zheng Y, Seibel M; DVC Research/Equipment Grant.

2011

  • MOLECULAR IMAGER CHEMIDoc XRS SYSTEM & MINI P ROTEAN GEL/TRANSBLOT Cell SYSTEM (BIO-RAD. AUSTRALIA; Allan C, Handelsman D, Zhou H, Seibel M, Kennerson M, Nicholson G, Blair I, Le Couteur D, McMahon A, Hart D, Clark G, Simanainen U; National Health and Medical Research Council (NHMRC)/Equipment Grants.

Selected publications

Download citations: PDF RTF Endnote

Journals

  • Bryant, C., Fromm, P., Kupresanin, F., Clark, G., Lee, K., Clarke, C., Silveira, P., Suen, H., Brown, R., Newman, E., Ho, J., Bradstock, K., Joshua, D., Hart, D., et al (2016). A CD2 high-expressing stress-resistant human plasmacytoid dendritic-cell subset. Immunology and Cell Biology, 94(5), 447-457. [More Information]
  • Fromm, P., Kupresanin, F., Brooks, A., Dunbar, P., Haniffa, M., Hart, D., Clark, G. (2016). A multi-laboratory comparison of blood dendritic cell populations. Clinical & Translational Immunology, 5(4), 1-9. [More Information]
  • Lo, T., Silveira, P., Fromm, P., Verma, N., Vu, P., Kupresanin, F., Adam, R., Kato, M., Cogger, V., Clark, G., Hart, D. (2016). Characterization of the expression and function of the C-type lectin receptor CD302 in mice and humans reveals a role in dendritic cell migration. The Journal of Immunology, 197(3), 885-898. [More Information]
  • Fromm, P., Papadimitrious, M., Hsu, J., Van Kooten Losio, N., Verma, N., Ho Lo, T., Silveira, P., Bryant, C., Turtle, C., Prue, R., Horvath, L., Bradstock, K., Joshua, D., Clark, G., Hart, D., et al (2016). CMRF-56+ blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses. OncoImmunology, 5(6), 1-12. [More Information]
  • Seldon, T., Pryor, R., Palkova, A., Jones, M., Verma, N., Findova, M., Braet, K., Sheng, Y., Fan, Y., Zhou, E., Fromm, P., Silveira, P., Elgundi, Z., Ju, X., Clark, G., Bradstock, K., Hart, D., et al (2016). Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation. Leukemia, 30(3), 692-700. [More Information]
  • Clark, G., Kupresanin, F., Fromm, P., Ju, X., Muusers, L., Silveira, P., Elgundi, Z., Gasiorowski, R., Papadimitrious, M., Bryant, C., Lee, K., Harman, A., Hart, D., et al (2016). New insights into the phenotype of human dendritic cell populations. Clinical & Translational Immunology, 5(1), 1-12. [More Information]
  • Clark, G., Stockinger, H., Balderas, R., van Zelm, M., Zola, H., Hart, D., Engel, P. (2016). Nomenclature of CD molecules from the Tenth Human Leucocyte Differentiation Antigen Workshop. Clinical & Translational Immunology, 5(1), 1-3. [More Information]
  • Engel, P., Boumsell, L., Balderas, R., Bensussan, A., Gattei, V., Horejsi, V., Jin, B., Malavasi, F., Mortari, F., Schwartz-Albiez, R., Clark, G. (2015). CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology. Journal of Immunology, 195(10), 4555-4563. [More Information]
  • Gasiorowski, R., Clark, G., Bradstock, K., Hart, D. (2014). Antibody therapy for acute myeloid leukaemia. British Journal of Haematology, 164(4), 481-495. [More Information]
  • Gasiorowski, R., Ju, X., Hart, D., Clark, G. (2013). CD300 molecule regulation of human dendritic cell functions. Immunology Letters, 149(1-2), 93-100. [More Information]
  • Ding, Y., Ju, X., Azlan, M., Hart, D., Clark, G. (2011). Screening of the HLDA9 panel on peripheral blood dendritic cell populations. Immunology Letters, 134(2), 161-166. [More Information]
  • Jongbloed, S., Kassianos, A., McDonald, K., Clark, G., Ju, X., Angel, C., Chen, C., Dunbar, P., Wadley, R., jeet, V., Hart, D., et al (2010). Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. The Journal of Experimental Medicine, 207(6), 1247-1260. [More Information]
  • Clark, G., Ju, X., Tate, C., Hart, D. (2009). The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions. Trends in Immunology, 30(5), 209-217. [More Information]
  • Clark, G., Ju, X., Azlan, M., Tate, C., Ding, Y., Hart, D. (2009). The CD300 molecules regulate monocyte and dendritic cell functions. Immunobiology, 214, 730-736. [More Information]
  • Hart, D., Clark, G., Ju, X., Zenke, M. (2008). Cd300a and Cd300c on Plasmacytoid Dendritic Cells Are down-Regulated by Tlr7 and Tlr9 Ligand Induced Type I Interferon. Biology of Blood and Marrow Transplantation, 14(2), 118-118.
  • Ju, X., Zenke, M., Hart, D., Clark, G. (2008). CD300a/c regulate type I interferon and TNF-(alpha) secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood, 112, 1184-1194. [More Information]
  • Clark, G., Jamriska, L., Rao, M., Hart, D. (2007). Monocytes immunoselected via the novel monocyte specific molecule, CD300e, differentiate into active migratory dendritic cells. Journal of Immunotherapy, 30(3), 303-311. [More Information]
  • Hart, D., Rao, M., Ju, X., Clark, G. (2007). Novel Human CD4+ T Lymphocyte Subpopulations Defined by CD300a/c Molecule Expression. Blood, 110(11), 682a-682a.
  • Clark, G., Rao, M., Ju, X., Hart, D. (2007). Novel human CD4+ T lymphocyte subpopulations defined by CD300a/c molecule expression. Journal of Leukocyte Biology, 82(5), 1126-1135. [More Information]
  • Modra, C., Jamriska, L., Rao, M., Clark, G., Hart, D. (2006). MMRI-23: A potential role in AML antibody-mediated therapy. Blood, 108(11), 225b-225b.
  • Modra, C., Radford, K., Gardiner, D., Hart, D., Clark, G. (2005). An inhibitory molecule involved in myeloid and DC differentiation. Tissue Antigens: immune response genetics, 66(5), 494-494.
  • Clark, G., Munster, D., Yusuf, S., Hart, D. (2005). Eighth Leucocyte DiVerentiation Antigen Workshop DC section summary. Cellular Immunology, 236, 21-28. [More Information]
  • Collin, M., Munster, D., Clark, G., Wang, X., Dickinson, A., Hart, D. (2005). In vitro depletion of tissue-derived dendritic cells by CMRF-44 antibody and alemtuzumab: implications for the control of Graft-versus-host disease. Transplantation, 79(6), 722-725. [More Information]
  • Hardy, M., Kassianos, A., Clark, G., Hart, D., Radford, K. (2005). Production of IL-2, IL-12, and IL-10 by human blood myeloid dendritic cells. Tissue Antigens: immune response genetics, 66(5), 437-437.

2016

  • Bryant, C., Fromm, P., Kupresanin, F., Clark, G., Lee, K., Clarke, C., Silveira, P., Suen, H., Brown, R., Newman, E., Ho, J., Bradstock, K., Joshua, D., Hart, D., et al (2016). A CD2 high-expressing stress-resistant human plasmacytoid dendritic-cell subset. Immunology and Cell Biology, 94(5), 447-457. [More Information]
  • Fromm, P., Kupresanin, F., Brooks, A., Dunbar, P., Haniffa, M., Hart, D., Clark, G. (2016). A multi-laboratory comparison of blood dendritic cell populations. Clinical & Translational Immunology, 5(4), 1-9. [More Information]
  • Lo, T., Silveira, P., Fromm, P., Verma, N., Vu, P., Kupresanin, F., Adam, R., Kato, M., Cogger, V., Clark, G., Hart, D. (2016). Characterization of the expression and function of the C-type lectin receptor CD302 in mice and humans reveals a role in dendritic cell migration. The Journal of Immunology, 197(3), 885-898. [More Information]
  • Fromm, P., Papadimitrious, M., Hsu, J., Van Kooten Losio, N., Verma, N., Ho Lo, T., Silveira, P., Bryant, C., Turtle, C., Prue, R., Horvath, L., Bradstock, K., Joshua, D., Clark, G., Hart, D., et al (2016). CMRF-56+ blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses. OncoImmunology, 5(6), 1-12. [More Information]
  • Seldon, T., Pryor, R., Palkova, A., Jones, M., Verma, N., Findova, M., Braet, K., Sheng, Y., Fan, Y., Zhou, E., Fromm, P., Silveira, P., Elgundi, Z., Ju, X., Clark, G., Bradstock, K., Hart, D., et al (2016). Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation. Leukemia, 30(3), 692-700. [More Information]
  • Clark, G., Kupresanin, F., Fromm, P., Ju, X., Muusers, L., Silveira, P., Elgundi, Z., Gasiorowski, R., Papadimitrious, M., Bryant, C., Lee, K., Harman, A., Hart, D., et al (2016). New insights into the phenotype of human dendritic cell populations. Clinical & Translational Immunology, 5(1), 1-12. [More Information]
  • Clark, G., Stockinger, H., Balderas, R., van Zelm, M., Zola, H., Hart, D., Engel, P. (2016). Nomenclature of CD molecules from the Tenth Human Leucocyte Differentiation Antigen Workshop. Clinical & Translational Immunology, 5(1), 1-3. [More Information]

2015

  • Engel, P., Boumsell, L., Balderas, R., Bensussan, A., Gattei, V., Horejsi, V., Jin, B., Malavasi, F., Mortari, F., Schwartz-Albiez, R., Clark, G. (2015). CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology. Journal of Immunology, 195(10), 4555-4563. [More Information]

2014

  • Gasiorowski, R., Clark, G., Bradstock, K., Hart, D. (2014). Antibody therapy for acute myeloid leukaemia. British Journal of Haematology, 164(4), 481-495. [More Information]

2013

  • Gasiorowski, R., Ju, X., Hart, D., Clark, G. (2013). CD300 molecule regulation of human dendritic cell functions. Immunology Letters, 149(1-2), 93-100. [More Information]

2011

  • Ding, Y., Ju, X., Azlan, M., Hart, D., Clark, G. (2011). Screening of the HLDA9 panel on peripheral blood dendritic cell populations. Immunology Letters, 134(2), 161-166. [More Information]

2010

  • Jongbloed, S., Kassianos, A., McDonald, K., Clark, G., Ju, X., Angel, C., Chen, C., Dunbar, P., Wadley, R., jeet, V., Hart, D., et al (2010). Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. The Journal of Experimental Medicine, 207(6), 1247-1260. [More Information]

2009

  • Clark, G., Ju, X., Tate, C., Hart, D. (2009). The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions. Trends in Immunology, 30(5), 209-217. [More Information]
  • Clark, G., Ju, X., Azlan, M., Tate, C., Ding, Y., Hart, D. (2009). The CD300 molecules regulate monocyte and dendritic cell functions. Immunobiology, 214, 730-736. [More Information]

2008

  • Hart, D., Clark, G., Ju, X., Zenke, M. (2008). Cd300a and Cd300c on Plasmacytoid Dendritic Cells Are down-Regulated by Tlr7 and Tlr9 Ligand Induced Type I Interferon. Biology of Blood and Marrow Transplantation, 14(2), 118-118.
  • Ju, X., Zenke, M., Hart, D., Clark, G. (2008). CD300a/c regulate type I interferon and TNF-(alpha) secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood, 112, 1184-1194. [More Information]

2007

  • Clark, G., Jamriska, L., Rao, M., Hart, D. (2007). Monocytes immunoselected via the novel monocyte specific molecule, CD300e, differentiate into active migratory dendritic cells. Journal of Immunotherapy, 30(3), 303-311. [More Information]
  • Hart, D., Rao, M., Ju, X., Clark, G. (2007). Novel Human CD4+ T Lymphocyte Subpopulations Defined by CD300a/c Molecule Expression. Blood, 110(11), 682a-682a.
  • Clark, G., Rao, M., Ju, X., Hart, D. (2007). Novel human CD4+ T lymphocyte subpopulations defined by CD300a/c molecule expression. Journal of Leukocyte Biology, 82(5), 1126-1135. [More Information]

2006

  • Modra, C., Jamriska, L., Rao, M., Clark, G., Hart, D. (2006). MMRI-23: A potential role in AML antibody-mediated therapy. Blood, 108(11), 225b-225b.

2005

  • Modra, C., Radford, K., Gardiner, D., Hart, D., Clark, G. (2005). An inhibitory molecule involved in myeloid and DC differentiation. Tissue Antigens: immune response genetics, 66(5), 494-494.
  • Clark, G., Munster, D., Yusuf, S., Hart, D. (2005). Eighth Leucocyte DiVerentiation Antigen Workshop DC section summary. Cellular Immunology, 236, 21-28. [More Information]
  • Collin, M., Munster, D., Clark, G., Wang, X., Dickinson, A., Hart, D. (2005). In vitro depletion of tissue-derived dendritic cells by CMRF-44 antibody and alemtuzumab: implications for the control of Graft-versus-host disease. Transplantation, 79(6), 722-725. [More Information]
  • Hardy, M., Kassianos, A., Clark, G., Hart, D., Radford, K. (2005). Production of IL-2, IL-12, and IL-10 by human blood myeloid dendritic cells. Tissue Antigens: immune response genetics, 66(5), 437-437.

To update your profile click here. For support on your academic profile contact .