Dr Grant Hill-Cawthorne

Lecturer in Communicable Disease Epidemiology
Marie Bashir Institute for Infectious Diseases and Biosecurity
Sydney School of Public Health


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Biographical details

I studied medicine in Cambridge and during my junior doctor years was very interested in both neurology and infectious diseases. Clinically I specialised in medical microbiology, keeping a particular interest in neurological infections. For the past 3 years I have been in Saudi Arabia developing a pathogen genomics laboratory where I have gained firsthand experience of second generation sequencing and bioinformatics.

Research interests

Infectious diseases and medical microbiology are undergoing the most significant shift since PCR was introduced. By the end of this decade, sequencing will have become the main option when investigating any outbreak or infection. I study the interface between genomics as a pure science and its translation into clinical benefits.

At present I am examining the worldwide genomics of tuberculosis, the use of sequencing to characterise MRSA strains and the genomic variations in BCG vaccine strains used around the globe.

To get copies of my publications please see sydney.academia.edu

Follow me on Twitter: @drbrainbugz

And go to clinicalvirology.org for my weekly and monthly News and Journal Watch

Teaching and supervision

Master of International Public Health

MIPH5112 Global Communicable Disease Control

MIPH5132 Global Burden of Disease and Research Methods

Master of Public Health

PUBH5117 Communicable Disease Control

International links

Saudi Arabia

(King Abdullah University of Science and Technology) University at which I did my PhD. Many ongoing collaborative projects on pathogen genomics.

United Kingdom

(London School of Hygiene and Tropical Medicine) Ongoing study on global diversity of tuberculosis

United Kingdom

(National Clinical Guideline Centre) National guideline on chronic hepatitis B (National Institute for Health and Clinical Excellence)

United Kingdom

(University of Cambridge) Research on alemtuzumab for multiple sclerosis and neuroimmunology

Selected publications

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Journals

  • Coll, F., Preston, M., Guerra-Assuncao, J., Hill-Cawthorne, G., Harris, D., Perdigao, J., Viveiros, M., Portugal, I., Drobniewski, F., Gagneux, S., et al (2014). PolyTB: A genomic variation map for Mycobacterium tuberculosis. Tuberculosis, 94(3), 346-354. [More Information]
  • Ghany, M., Chander, J., Mutreja, A., Hill-Cawthorne, G., Ali, S., Naeem, R., Thomson, N., Dougan, G., Pain, A. (2014). The Population Structure of Vibrio cholerae from the Chandigarh Region of Northern India. PLoS Neglected Tropical Diseases, 8(7), e2981. [More Information]
  • Banerjee, A., Mor, S., Kok, J., Sorrell, T., Hill-Cawthorne, G. (2014). Vulnerability, hysteria and fear - conquering Ebola virus. Medical Journal of Australia, 201(6), 320-321.
  • Sarri, G., Westby, M., Kelsey, A., Ritchie, G., Hill-Cawthorne, G., Thomas, H. (2013). Chronic hepatitis B in children, young people and adults: summary of the new NICE guideline. Viral Hepatitis in Practice, 5(2), 4-7.
  • Sarri, G., Westby, M., Bermingham, S., Hill-Cawthorne, G., Thomas, T. (2013). Diagnosis and management of chronic hepatitis B in children, young people, and adults: summary of NICE guidance. BMJ, 346, 1-5. [More Information]
  • Jones, J., Thompson, S., Loh, P., Davies, J., Tuohy, O., Curry, A., Azzopardi, L., Hill-Cawthorne, G., Fahey, M., Compston, A., et al (2013). Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 110(50), 20200-20205. [More Information]
  • Sarri, G., Ritchie, G., Hill-Cawthorne, G. (2013). Identification, testing, and support are key in chronic hepatitis B. Guidelines in Practice, 16(11), 11-24.
  • Reid, A., Vermont, S., Cotton, J., Harris, D., Hill-Cawthorne, G., Konen-Waisman, S., Latham, S., Mourier, T., Norton, R., Quail, M., et al (2012). Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathogens, 8(3), e1002567. [More Information]
  • Hill-Cawthorne, G., Button, T., Tuohy, O., Jones, J., May, K., Somerfield, J., Green, A., Giovannoni, G., Compston, A., Fahey, M., et al (2012). Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 83(3), 298-304. [More Information]
  • Somer�?eld, J., Hill-Cawthorne, G., Lin, A., Zandi, M., McCarthy, C., Jones, J., Willcox, M., Shaw, D., Thompson, S., Compston, A., et al (2011). A Novel Strategy To Reduce the Immunogenicity of Biological Therapies. The Journal of Immunology, 185(1), 763-768. [More Information]
  • Chakrabarti, B., Dudbridge, F., Kent, L., Wheelwright, S., Hill-Cawthorne, G., Allison, C., Banerjee-Basu, S., Baron-Cohen, S. (2011). Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Autism Research, 2(3), 157-177. [More Information]

Conferences

  • Hill-Cawthorne, G. (2011). Long-term lymphocyte reconstitution after alemtuzumab treatment of multiple scierosis. King Abdullah University of Science and Technology Graduate Research Symposium.

2014

  • Coll, F., Preston, M., Guerra-Assuncao, J., Hill-Cawthorne, G., Harris, D., Perdigao, J., Viveiros, M., Portugal, I., Drobniewski, F., Gagneux, S., et al (2014). PolyTB: A genomic variation map for Mycobacterium tuberculosis. Tuberculosis, 94(3), 346-354. [More Information]
  • Ghany, M., Chander, J., Mutreja, A., Hill-Cawthorne, G., Ali, S., Naeem, R., Thomson, N., Dougan, G., Pain, A. (2014). The Population Structure of Vibrio cholerae from the Chandigarh Region of Northern India. PLoS Neglected Tropical Diseases, 8(7), e2981. [More Information]
  • Banerjee, A., Mor, S., Kok, J., Sorrell, T., Hill-Cawthorne, G. (2014). Vulnerability, hysteria and fear - conquering Ebola virus. Medical Journal of Australia, 201(6), 320-321.

2013

  • Sarri, G., Westby, M., Kelsey, A., Ritchie, G., Hill-Cawthorne, G., Thomas, H. (2013). Chronic hepatitis B in children, young people and adults: summary of the new NICE guideline. Viral Hepatitis in Practice, 5(2), 4-7.
  • Sarri, G., Westby, M., Bermingham, S., Hill-Cawthorne, G., Thomas, T. (2013). Diagnosis and management of chronic hepatitis B in children, young people, and adults: summary of NICE guidance. BMJ, 346, 1-5. [More Information]
  • Jones, J., Thompson, S., Loh, P., Davies, J., Tuohy, O., Curry, A., Azzopardi, L., Hill-Cawthorne, G., Fahey, M., Compston, A., et al (2013). Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 110(50), 20200-20205. [More Information]
  • Sarri, G., Ritchie, G., Hill-Cawthorne, G. (2013). Identification, testing, and support are key in chronic hepatitis B. Guidelines in Practice, 16(11), 11-24.

2012

  • Reid, A., Vermont, S., Cotton, J., Harris, D., Hill-Cawthorne, G., Konen-Waisman, S., Latham, S., Mourier, T., Norton, R., Quail, M., et al (2012). Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy. PLoS Pathogens, 8(3), e1002567. [More Information]
  • Hill-Cawthorne, G., Button, T., Tuohy, O., Jones, J., May, K., Somerfield, J., Green, A., Giovannoni, G., Compston, A., Fahey, M., et al (2012). Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 83(3), 298-304. [More Information]

2011

  • Somer�?eld, J., Hill-Cawthorne, G., Lin, A., Zandi, M., McCarthy, C., Jones, J., Willcox, M., Shaw, D., Thompson, S., Compston, A., et al (2011). A Novel Strategy To Reduce the Immunogenicity of Biological Therapies. The Journal of Immunology, 185(1), 763-768. [More Information]
  • Chakrabarti, B., Dudbridge, F., Kent, L., Wheelwright, S., Hill-Cawthorne, G., Allison, C., Banerjee-Basu, S., Baron-Cohen, S. (2011). Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Autism Research, 2(3), 157-177. [More Information]
  • Hill-Cawthorne, G. (2011). Long-term lymphocyte reconstitution after alemtuzumab treatment of multiple scierosis. King Abdullah University of Science and Technology Graduate Research Symposium.

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