Associate Professor Greg King

MB ChB, PhD, FRACP
Associate Professor
Medicine, Northern Clinical School

Telephone 9463 2935
Fax 9463 2099

Website Related website

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International links

Belgium

(Department of Pneumology, Akademisch Ziekenhuis, Vrije, Universiteit Brussel Brussels) Collaboration in small airway physiology with Professor Sylvia Vernbanck.

Japan

(Tsukinowa, Seta Otsu Shiga 520-2192) Collaboration with Dr Yasutaka Nakano on CT measurements of airway structure.

New Zealand

(The Bioengineering Institute The University Of Auckland) Collaborative project in mathematical modelling of the lung. Two PhD students.

Selected grants

2014

  • National Clinical Centre of Research Excellence in Severe Asthma; King G, Gibson P, Marks G, Thompson B, Upham J, James A; National Health and Medical Research Council (NHMRC)/Centres of Research Excellence.
  • The pathogenisis of non-reversible airflow limitation in asthma; King G; DVC Research/Bridging Support Grant.
  • CSI-Sydney: New technologies to treat chronic sinus infection; Young P, Traini D, King G, Bailey D, Whitchurch C, Rohanizadeh R; National Health and Medical Research Council (NHMRC)/Development Grants.
  • Airway extracellular matrix and smooth muscle in chronic obstructive pulmonary disease (COPD); James A, King G, Noble P, McFawn P, McParland B; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Prediction of clinical outcomes in COPD from home monitoring of lung function variability; Thamrin C, King G; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Localised airway reactivity as a determinant of asthma control and AHR; King G, Salome C, Berend N; National Health and Medical Research Council (NHMRC)/Project Grants.

2011

  • Physiological aetiology of Refractory Asthma; King G; National Health and Medical Research Council (NHMRC)/Project Grants.

2010

  • NHMRC Practitioner Fellowship 1; King G; National Health and Medical Research Council (NHMRC)/Career Awards: Practitioner Fellowships.
  • Is asthma in the elderly a disease of the peripheral airways?; King G, Downie S, Salome C, Berend N, Brown N, Downie S; National Health and Medical Research Council (NHMRC)/Project Grants.

2008

  • How do thick airway walls affect airway hyperresponsiveness in asthma?; King G, Salome C, Berend N, Brown N; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • Does the pattern of ventilation distribution predict airway hyperresponsiveness?; King G, Salome C, Berend N; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Functional assessment in the management of radiotherapy of lung cancer; Cox J, Bailey D, King G, Morgan G; Cancer Institute New South Wales/Research Grant.

2005

  • Respiratory and Sleep Medicine; Jenkins C, Hensley M, Alison J, Britton W, Irwig L, Rogers N, Rose B, Marks G, Grunstein R, Bye P, Anderson S, King G, Berend N, Gibson P; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • The effects of heterogenity and airway closure on airway distensibility measurements in asthma; King G; University of Sydney/Bridging Support.
  • X-ray Micro-tomography Validation of HRCT-Based Airway Measurements; Jones A, King G, King G; Australian Research Council (ARC)/Linkage Projects (LP).

2001

  • Airway wall thickness and heterogeneity are key determinants of asthmatic airway function; King G, Magnussen J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Abnormal smooth muscle behaviour in asthma:toward an in vivo test; King G, Salome C; National Health and Medical Research Council (NHMRC)/Project Grants.

2000

  • Not known; University of Sydney/Postdoctoral Fellowship.
  • Effect of deep inspiration inhibition during progressive airway smooth muscle activation; King G; Asthma Foundation of NSW/Research Grants.

Selected publications

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Journals

  • Timmins, S., Diba, C., Schoeffel, R., Salome, C., King, G., Thamrin, C. (2014). Changes in oscillatory impedance and nitrogen washout with combination fluticasone/salmeterol therapy in COPD. Respiratory Medicine, 108(2), 344-350. [More Information]
  • Zimmermann, S., Farah, C., King, G. (2014). Early COPD: How to identify it and is it worth treating? Medicine Today, 15(1), 34-38.
  • Chapman, D., Pascoe, C., Lee-Gosselin, A., Couture, C., Seow, C., Pare, P., Salome, C., King, G., Bosse, Y. (2014). Smooth muscle in the maintenance of increased airway resistance elicited by methacholine in humans. American Journal of Respiratory and Critical Care Medicine, 190(8), 879-885. [More Information]
  • Saadat, A., Zhu, B., Haghi, M., King, G., Colombo, G., Young, P., Traini, D. (2014). The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. Journal of Pharmacy and Pharmacology, 66(5), 639-645. [More Information]
  • Robinson, P., Latzin, P., Verbanck, S., Hall, G., Horsley, A., Gappa, M., Thamrin, C., Arets, H., Aurora, P., Fuchs, S., King, G., et al (2013). Consensus statement for inert gas washout measurement using multiple- and single- breath tests. The European Respiratory Journal, 41(3), 507-522. [More Information]
  • Timmins, S., Coatsworth, N., Palnitkar, G., Thamrin, C., Farrow, C., Schoeffel, R., Berend, N., Diba, C., Salome, C., King, G. (2013). Day-to-day variability of oscillatory impedance and spirometry in asthma and COPD. Respiratory Physiology and Neurobiology, 185(2), 416-424. [More Information]
  • Hulme, K., Salome, C., Brown, N., Berend, N., Agus, H., Horlyck, K., King, G., Chapman, D. (2013). Deep inspiration volume and the impaired reversal of bronchoconstriction in asthma. Respiratory Physiology and Neurobiology, 189(3), 506-512. [More Information]
  • Downie, S., Salome, C., Verbanck, S., Thompson, B., Berend, N., King, G. (2013). Effect of methacholine on peripheral lung mechanics and ventilation heterogeneity in asthma. Journal of Applied Physiology, 114(6), 770-777. [More Information]
  • Mahadev, S., Farah, C., King, G., Salome, C. (2013). Obesity, expiratory flow limitation and asthma symptoms. Pulmonary Pharmacology and Therapeutics, 26(4), 438-443. [More Information]
  • Thompson, B., Douglass, J., Ellis, M., Kelly, V., O'Hehir, R., King, G., Verbanck, S. (2013). Peripheral lung function in patients with stable and unstable asthma. Journal of Allergy and Clinical Immunology, 131(5), 1322-1328. [More Information]
  • Bilton, D., Daviskas, E., Anderson, S., Kolbe, J., King, G., Stirling, R., Thompson, B., Milne, D., Charlton, B. (2013). Phase 3 Randomised Study of the Efficacy and Safety of Inhaled Dry Powder Mannitol (Bronchitol) for the Symptomatic Treatment of Non-Cystic Fibrosis Bronchiectasis. Chest, 144(1), 215-225. [More Information]
  • Porsbjerg, C., Gibson, P., Pretto, J., Salome, C., Brown, N., Berend, N., King, G. (2013). Relationship between airway pathophysiology and airway inflammation in older asthmatics. Respirology, 18(7), 1128-1134. [More Information]
  • Kelly, V., Sands, S., Harris, R., Venegas, J., Brown, N., Stuart-Andrews, C., King, G., Thompson, B. (2013). Respiratory system reactance is an independent determinant of asthma control. Journal of Applied Physiology, 115(9), 1360-1369. [More Information]
  • Mahadev, S., Salome, C., Berend, N., King, G. (2013). The effect of low lung volume on airway function in obesity. Respiratory Physiology and Neurobiology, 188(2), 192-199. [More Information]
  • Timmins, S., Diba, C., Thamrin, C., Berend, N., Salome, C., King, G. (2013). The feasibility of home monitoring of impedance with the forced oscillation technique in chronic obstructive pulmonary disease subjects. Physiological measurement, 34(1), 67-81. [More Information]
  • Hardaker, K., Downie, S., Kermode, J., Berend, N., King, G., Salome, C. (2013). Ventilation heterogeneity is associated with airway responsiveness in asthma but not COPD. Respiratory Physiology and Neurobiology, 189, 106-111. [More Information]
  • Farrow, C., Salome, C., Harris, B., Bailey, D., Bailey, E., Berend, N., Young, I., King, G. (2012). Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma. Journal of Applied Physiology, 113(6), 958-966. [More Information]
  • Chapman, D., Berend, N., Horlyck, K., King, G., Salome, C. (2012). Does increased baseline ventilation heterogeneity following chest wall strapping predispose to airway hyperresponsiveness? Journal of Applied Physiology, 113(1), 25-30. [More Information]
  • Kelly, V., Brown, N., Sands, S., Borg, B., King, G., Thompson, B. (2012). Effect of airway smooth muscle tone on airway distensibility measured by the forced oscillation technique in adults with asthma. Journal of Applied Physiology, 112(9), 1494-1503. [More Information]
  • Baraket, M., Oliver, B., Burgess, J., Lim, S., King, G., Black, J. (2012). Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. Respiratory Research (Online), 13(2 February 2012), 1-11. [More Information]
  • King, G., Farah, C. (2012). Targeting airway remodelling in asthma: the how, what and where? Respirology, 17(4), 585-587. [More Information]
  • Timmins, S., Diba, C., Farrow, C., Schoeffel, R., Berend, N., Salome, C., King, G. (2012). The Relationship Between Airflow Obstruction, Emphysema Extent, and Small Airways Function in COPD. Chest, 142(2), 312-319. [More Information]
  • Farah, C., King, G., Brown, N., Downie, S., Kermode, J., Hardaker, K., Peters, M., Berend, N., Salome, C. (2012). The role of the small airways in the clinical expression of asthma in adults. Journal of Allergy and Clinical Immunology, 129(2), 381-387.e1. [More Information]
  • King, G. (2012). Tomographic Imaging of Small Airways. Respiration, 84(4), 265-274. [More Information]
  • Farah, C., King, G., Brown, N., Peters, M., Berend, N., Salome, C. (2012). Ventilation heterogeneity predicts asthma control in adults following inhaled corticosteroid dose titration. Journal of Allergy and Clinical Immunology, 130(1), 61-68. [More Information]
  • Bosse, Y., Chapman, D., Pare, P., King, G., Salome, C. (2011). A 'Good' muscle in a 'Bad' environment: the importance of airway smooth muscle force adaptation to airway hyperresponsiveness. Respiratory Physiology and Neurobiology, 179, 269-275. [More Information]
  • Meier, A., Farrow, C., Harris, B., King, G., Jones, A. (2011). Application of texture analysis to ventilation SPECT/CT data. Computerized Medical Imaging and Graphics, 35(6), 438-450. [More Information]
  • Lalloo, U., Walters, R., Adachi, M., DeGuia, T., Emelyanov, A., Fritscher, C., Hong, J., Jimenez, C., King, G., Lin, J., et al (2011). Asthma programmes in diverse regions of the world: challenges, successes and lessons learnt. International Journal of Tuberculosis and Lung Disease, 15(12), 1574-1586. [More Information]
  • King, G. (2011). Current and emerging imaging in relation to drug discovery in airways disease. Pulmonary Pharmacology and Therapeutics, 24(5), 497-504. [More Information]
  • McClean, M., Htun, C., King, G., Berend, N., Salome, C. (2011). Cut-Points for Response to Mannitol Challenges Using the Forced Oscillation Technique. Respiratory Medicine, 105(4), 533-540. [More Information]
  • King, G. (2011). Cutting edge technologies in respiratory research: Lung function testing. Respirology, 16(6), 883-890. [More Information]
  • Chapman, D., Berend, N., King, G., Salome, C. (2011). Effect of deep inspiration avoidance on ventilation heterogeneity and airway responsiveness in healthy adults. Journal of Applied Physiology, 110(5), 1400-1405. [More Information]
  • Diba, C., King, G., Berend, N., Salome, C. (2011). Improved respiratory system conductance following bronchodilator predicts reduced exertional dyspnoea. Respiratory Medicine, 105(9), 1345-1351. [More Information]
  • Farah, C., Kermode, J., Downie, S., Brown, N., Hardaker, K., Berend, N., King, G., Salome, C. (2011). Obesity Is a Determinant of Asthma Control, Independent of Inflammation and Lung Mechanics. Chest, 140(3), 659-666. [More Information]
  • Hardaker, K., Downie, S., Kermode, J., Farah, C., Brown, N., Berend, N., King, G., Salome, C. (2011). Predictors of Airway Hyperresponsiveness Differ Between Old and Young Patients With Asthma. Chest, 139(6), 1395-1401. [More Information]
  • Robinson, P., Turner, M., Brown, N., Salome, C., Berend, N., Marks, G., King, G. (2011). Procedures to improve the repeatability of forced oscillation measurements in school-aged children. Respiratory Physiology and Neurobiology, 177(2), 199-206. [More Information]
  • Lahzami, S., Schoeffel, R., Pechey, V., Reid, C., Greenwood, M., Salome, C., Berend, N., King, G. (2011). Small airways function declines after allogeneic haematopoietic stem cell transplantation. The European Respiratory Journal, 38(5), 1180-1188. [More Information]
  • Kelly, V., Brown, N., King, G., Thompson, B. (2011). The Bronchodilator Response of In Vivo Specific Airway Compliance in Adults with Asthma. Annals of Biomedical Engineering, 39(3), 1125-1135. [More Information]
  • Kermode, J., Brown, N., Hardaker, K., Farah, C., Berend, N., King, G., Salome, C. (2011). The effect of airway remodelling on airway hyper-responsiveness in asthma. Respiratory Medicine, 105(12), 1798-1804. [More Information]
  • Kelly, V., Brown, N., King, G., Thompson, B. (2010). A method to determine in vivo, specific airway compliance, in humans. Medical and Biological Engineering and Computing, 48(5), 489-496. [More Information]
  • Chapman, D., King, G., Berend, N., Diba, C., Salome, C. (2010). Avoiding Deep Inspirations Increases The Maximal Response To Methacholine Without Altering Sensitivity In Non-Asthmatics. Respiratory Physiology and Neurobiology, 173(2), 157-163. [More Information]
  • Salome, C., King, G., Berend, N. (2010). Physiology of obesity and effects on lung function. Journal of Applied Physiology, 108(1), 206-11. [More Information]
  • Brown, N., Xuan, W., Salome, C., Berend, N., Hunter, M., Musk, A., James, A., King, G. (2010). Reference equations for respiratory system resistance and reactance in adults. Respiratory Physiology and Neurobiology, 172(3), 162-168. [More Information]
  • King, G., Harris, B., Mahadev, S. (2010). V/Q SPECT: Utility for Investigation of Pulmonary Physiology. Seminars in Nuclear Medicine, 40(6), 467-473. [More Information]
  • Chapman, D., Berend, N., King, G., McParland, B., Salome, C. (2009). Deep inspirations protect against airway closure in nonasthmatic subjects. Journal of Applied Physiology, 107(2), 564-569. [More Information]
  • Deng, L., Bosse, Y., Brown, N., Chin, L., Connolly, S., Fairbank, N., King, G., Maksym, G., Pare, P., Seow, C., et al (2009). Stress and strain in the contractile and cytoskeletal filaments of airway smooth muscle. Pulmonary Pharmacology and Therapeutics, 22(5), 407-416. [More Information]
  • Harris, B., Bailey, D., Roach, P., Schembri, G., Ho Shon, I., Chicco, P., Bailey, E., King, G. (2008). A clinical comparison between traditional planar V/Q images and planar images generated from SPECT V/Q scintigraphy. Nuclear Medicine Communications, 29(4), 323-330. [More Information]
  • Chapman, D., Berend, N., King, G., Salome, C. (2008). Increased airway closure is a determinant of airway hyperresponsiveness. European Respiratory Journal, 32(6), 1563-1569. [More Information]
  • Berend, N., Salome, C., King, G. (2008). Mechanisms of airway hyperresponsiveness in asthma. Respirology, 13(5), 624-631. [More Information]
  • Harris, B., Bailey, D., Chicco, P., Bailey, E., Roach, P., King, G. (2008). Objective analysis of whole lung and lobar ventilation/perfusion relationships in pulmonary embolism. Clinical Physiology and Functional Imaging, 28(1), 14-26. [More Information]
  • Lahzami, S., King, G. (2008). Targeting small airways in asthma: the new challenge of inhaled corticosteroid treatment. The European Respiratory Journal, 31(6), 1145-7. [More Information]
  • Brown, N., Salome, C., Berend, N., Thorpe, C., King, G. (2007). Airway distensibility in adults with asthma and healthy adults, measured by forced oscillation technique. American Journal of Respiratory and Critical Care Medicine, 176(2), 129-137. [More Information]
  • An, S., Bai, T., Bates, J., Black, J., Brown, R., Brusasco, V., Chitano, P., Deng, L., King, G., McParland, B., et al (2007). Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. European Respiratory Journal, 29(5), 834-860. [More Information]
  • Thompson, B., King, G., Harding, R. (2007). Commentary on The role of the large airways on smooth muscle contraction in asthma".". Journal of Applied Physiology, 103(4), 1465; author reply 1466. [More Information]
  • Borger, P., Matsumoto, H., Boustany, S., Gencay, M., Burgess, J., King, G., Black, J., Tamm, M., Roth, M. (2007). Disease-specific expression and regulation of CCAAT/enhancer-binding proteins in asthma and chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology. [More Information]
  • Salome, C., Munoz, P., Berend, N., Thorpe, C., Schachter, L., King, G. (2007). Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. International Journal of Obesity, online, 1-8. [More Information]
  • Harris, B., Bailey, D., Roach, P., Bailey, E., King, G. (2007). Fusion imaging of computed tomographic pulmonary angiography and SPECT ventilation/perfusion scintigraphy: initial experience and potential benefit. European Journal of Nuclear Medicine and Molecular Imaging, 34(1), 135-142. [More Information]
  • Harris, B., Bailey, D., Miles, S., Bailey, E., Rogers, K., Roach, P., Thomas, P., Hensley, M., King, G. (2007). Objective analysis of tomographic ventilation-perfusion scintigraphy in pulmonary embolism. American Journal of Respiratory and Critical Care Medicine, 175(11), 1173-1180. [More Information]
  • Diba, C., Salome, C., Reddel, H., Thorpe, C., Toelle, B., King, G. (2007). Short-term variability of airway caliber - a marker of asthma? Journal of Applied Physiology, 103(1), 296-304. [More Information]
  • King, G., Salome, C. (2006). Multimodality measurements of small airways disease. European Respiratory Journal, 27(2), 250-252. [More Information]
  • Harris, B., Bailey, D., Roach, P., Marshman, D., McElduff, A., King, G. (2006). Use of Fusion Imaging to Localize an Ectopic Thoracic Parathyroid Adenoma. The Annals of Thoracic Surgery, 82. [More Information]
  • Ko, F., Diba, C., Roth, M., McKay, K., Johnson, P., Salome, C., King, G. (2005). A comparison of airway and serum matrix metalloproteinase-9 activity among normal subjects, asthmatic patients, and patients with asthmatic mucus hypersecretion. Chest, 127(6), 1919-1927. [More Information]
  • Coxson, H., Baile, E., King, G., Mayo, J. (2005). Diagnosis of subsegmental pulmonary emboli: a multi-center study using a porcine model. Journal of thoracic imaging, 20(1), 24-31. [More Information]
  • King, G., Downie, S., Verbanck, S., Thorpe, C., Berend, N., Salome, C., Thompson, B. (2005). Effects of methacholine on small airway function measured by forced oscillation technique and multiple breath nitrogen washout in normal subjects. Respiratory Physiology and Neurobiology, 148(01-Feb), 165-177. [More Information]
  • King, G., Brown, N., Diba, C., Thorpe, C., Munoz, P., Marks, G., Toelle, B., Ng, K., Berend, N., Salome, C. (2005). The effects of body weight on airway calibre. European Respiratory Journal, 25(5), 896-901. [More Information]
  • Berend, N., Salome, C., Thompson, B., Brown, N., Thorpe, C., Verbanck, S., Downie, S., King, G. (2004). A Comparison Of Two Methods For Measuring Airway Distensibility: Nitrogen Washout And The Forced Oscillation Technique. Physiological Measurement, 25(4), 1067-1075.
  • Roth, M., Johnson, P., Borger, P., Bihl, M., Rudiger, J., King, G., Ge, Q., Hostettler, K., Burgess, J., Black, J., et al (2004). Dysfunctional Interaction Of C/EBPα And The Glucocorticoid Receptor In Asthmatic Bronchial Smooth-Muscle Cells. New England Journal of Medicine, 351(6), 560-574.
  • King, G., Carroll, J., Muller, N., Whittall, K., Gao, M., Nakano, Y., Pare, P. (2004). Heterogeneity Of Narrowing In Normal And Asthmatic Airways Measured By Hrct. European Respiratory Journal, 24(2), 211-218.
  • Thorpe, C., Salome, C., Berend, N., King, G. (2004). Modeling Airway Resistance Dynamics After Tidal And Deep Inspirations. Journal of Applied Physiology, 97(5), 1643-1653.
  • Salome, C., Thorpe, C., Diba, C., Brown, N., Berend, N., King, G. (2003). Airway re-narrowing following deep inspiration in asthmatic and nonasthmatic subjects. European Respiratory Journal, 22, 62-68.
  • Burgess, J., Johnson, P., Ge, Q., Au, W., Poniris, M., McParland, B., King, G., Roth, M., Black, J. (2003). Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 167(1), 71-77.
  • Roth, M., Johnson, P., Rudiger, J., King, G., Ge, Q., Burgess, J., Anderson, G., Tamm, M., Black, J. (2002). Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. The Lancet, 360(9342), 1293-1299.
  • Nakano, Y., Muller, N., King, G., Niimi, A., Kalloger, S., Mishima, M., Pare, P. (2002). Quantitative assessment of airway remodeling using high-resolution CT. Chest, 122(6 Supplement), 271S-275S.
  • Crossley, M., King, G., Pyke, S., Tansey, C. (2002). Reaction of 5-nitro-octaethylporphyrins with nucleophiles. Journal of Porphyrins and Phthalocyanines, 6(11), 685-694.
  • Blair, D., Bennett, M., King, G., Robson, S. (2001). Vesicle-associated proteins and transmitter release from sympathetic ganglionic boutons. NeuroReport, 12, 607-610.

2014

  • Timmins, S., Diba, C., Schoeffel, R., Salome, C., King, G., Thamrin, C. (2014). Changes in oscillatory impedance and nitrogen washout with combination fluticasone/salmeterol therapy in COPD. Respiratory Medicine, 108(2), 344-350. [More Information]
  • Zimmermann, S., Farah, C., King, G. (2014). Early COPD: How to identify it and is it worth treating? Medicine Today, 15(1), 34-38.
  • Chapman, D., Pascoe, C., Lee-Gosselin, A., Couture, C., Seow, C., Pare, P., Salome, C., King, G., Bosse, Y. (2014). Smooth muscle in the maintenance of increased airway resistance elicited by methacholine in humans. American Journal of Respiratory and Critical Care Medicine, 190(8), 879-885. [More Information]
  • Saadat, A., Zhu, B., Haghi, M., King, G., Colombo, G., Young, P., Traini, D. (2014). The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. Journal of Pharmacy and Pharmacology, 66(5), 639-645. [More Information]

2013

  • Robinson, P., Latzin, P., Verbanck, S., Hall, G., Horsley, A., Gappa, M., Thamrin, C., Arets, H., Aurora, P., Fuchs, S., King, G., et al (2013). Consensus statement for inert gas washout measurement using multiple- and single- breath tests. The European Respiratory Journal, 41(3), 507-522. [More Information]
  • Timmins, S., Coatsworth, N., Palnitkar, G., Thamrin, C., Farrow, C., Schoeffel, R., Berend, N., Diba, C., Salome, C., King, G. (2013). Day-to-day variability of oscillatory impedance and spirometry in asthma and COPD. Respiratory Physiology and Neurobiology, 185(2), 416-424. [More Information]
  • Hulme, K., Salome, C., Brown, N., Berend, N., Agus, H., Horlyck, K., King, G., Chapman, D. (2013). Deep inspiration volume and the impaired reversal of bronchoconstriction in asthma. Respiratory Physiology and Neurobiology, 189(3), 506-512. [More Information]
  • Downie, S., Salome, C., Verbanck, S., Thompson, B., Berend, N., King, G. (2013). Effect of methacholine on peripheral lung mechanics and ventilation heterogeneity in asthma. Journal of Applied Physiology, 114(6), 770-777. [More Information]
  • Mahadev, S., Farah, C., King, G., Salome, C. (2013). Obesity, expiratory flow limitation and asthma symptoms. Pulmonary Pharmacology and Therapeutics, 26(4), 438-443. [More Information]
  • Thompson, B., Douglass, J., Ellis, M., Kelly, V., O'Hehir, R., King, G., Verbanck, S. (2013). Peripheral lung function in patients with stable and unstable asthma. Journal of Allergy and Clinical Immunology, 131(5), 1322-1328. [More Information]
  • Bilton, D., Daviskas, E., Anderson, S., Kolbe, J., King, G., Stirling, R., Thompson, B., Milne, D., Charlton, B. (2013). Phase 3 Randomised Study of the Efficacy and Safety of Inhaled Dry Powder Mannitol (Bronchitol) for the Symptomatic Treatment of Non-Cystic Fibrosis Bronchiectasis. Chest, 144(1), 215-225. [More Information]
  • Porsbjerg, C., Gibson, P., Pretto, J., Salome, C., Brown, N., Berend, N., King, G. (2013). Relationship between airway pathophysiology and airway inflammation in older asthmatics. Respirology, 18(7), 1128-1134. [More Information]
  • Kelly, V., Sands, S., Harris, R., Venegas, J., Brown, N., Stuart-Andrews, C., King, G., Thompson, B. (2013). Respiratory system reactance is an independent determinant of asthma control. Journal of Applied Physiology, 115(9), 1360-1369. [More Information]
  • Mahadev, S., Salome, C., Berend, N., King, G. (2013). The effect of low lung volume on airway function in obesity. Respiratory Physiology and Neurobiology, 188(2), 192-199. [More Information]
  • Timmins, S., Diba, C., Thamrin, C., Berend, N., Salome, C., King, G. (2013). The feasibility of home monitoring of impedance with the forced oscillation technique in chronic obstructive pulmonary disease subjects. Physiological measurement, 34(1), 67-81. [More Information]
  • Hardaker, K., Downie, S., Kermode, J., Berend, N., King, G., Salome, C. (2013). Ventilation heterogeneity is associated with airway responsiveness in asthma but not COPD. Respiratory Physiology and Neurobiology, 189, 106-111. [More Information]

2012

  • Farrow, C., Salome, C., Harris, B., Bailey, D., Bailey, E., Berend, N., Young, I., King, G. (2012). Airway closure on imaging relates to airway hyperresponsiveness and peripheral airway disease in asthma. Journal of Applied Physiology, 113(6), 958-966. [More Information]
  • Chapman, D., Berend, N., Horlyck, K., King, G., Salome, C. (2012). Does increased baseline ventilation heterogeneity following chest wall strapping predispose to airway hyperresponsiveness? Journal of Applied Physiology, 113(1), 25-30. [More Information]
  • Kelly, V., Brown, N., Sands, S., Borg, B., King, G., Thompson, B. (2012). Effect of airway smooth muscle tone on airway distensibility measured by the forced oscillation technique in adults with asthma. Journal of Applied Physiology, 112(9), 1494-1503. [More Information]
  • Baraket, M., Oliver, B., Burgess, J., Lim, S., King, G., Black, J. (2012). Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. Respiratory Research (Online), 13(2 February 2012), 1-11. [More Information]
  • King, G., Farah, C. (2012). Targeting airway remodelling in asthma: the how, what and where? Respirology, 17(4), 585-587. [More Information]
  • Timmins, S., Diba, C., Farrow, C., Schoeffel, R., Berend, N., Salome, C., King, G. (2012). The Relationship Between Airflow Obstruction, Emphysema Extent, and Small Airways Function in COPD. Chest, 142(2), 312-319. [More Information]
  • Farah, C., King, G., Brown, N., Downie, S., Kermode, J., Hardaker, K., Peters, M., Berend, N., Salome, C. (2012). The role of the small airways in the clinical expression of asthma in adults. Journal of Allergy and Clinical Immunology, 129(2), 381-387.e1. [More Information]
  • King, G. (2012). Tomographic Imaging of Small Airways. Respiration, 84(4), 265-274. [More Information]
  • Farah, C., King, G., Brown, N., Peters, M., Berend, N., Salome, C. (2012). Ventilation heterogeneity predicts asthma control in adults following inhaled corticosteroid dose titration. Journal of Allergy and Clinical Immunology, 130(1), 61-68. [More Information]

2011

  • Bosse, Y., Chapman, D., Pare, P., King, G., Salome, C. (2011). A 'Good' muscle in a 'Bad' environment: the importance of airway smooth muscle force adaptation to airway hyperresponsiveness. Respiratory Physiology and Neurobiology, 179, 269-275. [More Information]
  • Meier, A., Farrow, C., Harris, B., King, G., Jones, A. (2011). Application of texture analysis to ventilation SPECT/CT data. Computerized Medical Imaging and Graphics, 35(6), 438-450. [More Information]
  • Lalloo, U., Walters, R., Adachi, M., DeGuia, T., Emelyanov, A., Fritscher, C., Hong, J., Jimenez, C., King, G., Lin, J., et al (2011). Asthma programmes in diverse regions of the world: challenges, successes and lessons learnt. International Journal of Tuberculosis and Lung Disease, 15(12), 1574-1586. [More Information]
  • King, G. (2011). Current and emerging imaging in relation to drug discovery in airways disease. Pulmonary Pharmacology and Therapeutics, 24(5), 497-504. [More Information]
  • McClean, M., Htun, C., King, G., Berend, N., Salome, C. (2011). Cut-Points for Response to Mannitol Challenges Using the Forced Oscillation Technique. Respiratory Medicine, 105(4), 533-540. [More Information]
  • King, G. (2011). Cutting edge technologies in respiratory research: Lung function testing. Respirology, 16(6), 883-890. [More Information]
  • Chapman, D., Berend, N., King, G., Salome, C. (2011). Effect of deep inspiration avoidance on ventilation heterogeneity and airway responsiveness in healthy adults. Journal of Applied Physiology, 110(5), 1400-1405. [More Information]
  • Diba, C., King, G., Berend, N., Salome, C. (2011). Improved respiratory system conductance following bronchodilator predicts reduced exertional dyspnoea. Respiratory Medicine, 105(9), 1345-1351. [More Information]
  • Farah, C., Kermode, J., Downie, S., Brown, N., Hardaker, K., Berend, N., King, G., Salome, C. (2011). Obesity Is a Determinant of Asthma Control, Independent of Inflammation and Lung Mechanics. Chest, 140(3), 659-666. [More Information]
  • Hardaker, K., Downie, S., Kermode, J., Farah, C., Brown, N., Berend, N., King, G., Salome, C. (2011). Predictors of Airway Hyperresponsiveness Differ Between Old and Young Patients With Asthma. Chest, 139(6), 1395-1401. [More Information]
  • Robinson, P., Turner, M., Brown, N., Salome, C., Berend, N., Marks, G., King, G. (2011). Procedures to improve the repeatability of forced oscillation measurements in school-aged children. Respiratory Physiology and Neurobiology, 177(2), 199-206. [More Information]
  • Lahzami, S., Schoeffel, R., Pechey, V., Reid, C., Greenwood, M., Salome, C., Berend, N., King, G. (2011). Small airways function declines after allogeneic haematopoietic stem cell transplantation. The European Respiratory Journal, 38(5), 1180-1188. [More Information]
  • Kelly, V., Brown, N., King, G., Thompson, B. (2011). The Bronchodilator Response of In Vivo Specific Airway Compliance in Adults with Asthma. Annals of Biomedical Engineering, 39(3), 1125-1135. [More Information]
  • Kermode, J., Brown, N., Hardaker, K., Farah, C., Berend, N., King, G., Salome, C. (2011). The effect of airway remodelling on airway hyper-responsiveness in asthma. Respiratory Medicine, 105(12), 1798-1804. [More Information]

2010

  • Kelly, V., Brown, N., King, G., Thompson, B. (2010). A method to determine in vivo, specific airway compliance, in humans. Medical and Biological Engineering and Computing, 48(5), 489-496. [More Information]
  • Chapman, D., King, G., Berend, N., Diba, C., Salome, C. (2010). Avoiding Deep Inspirations Increases The Maximal Response To Methacholine Without Altering Sensitivity In Non-Asthmatics. Respiratory Physiology and Neurobiology, 173(2), 157-163. [More Information]
  • Salome, C., King, G., Berend, N. (2010). Physiology of obesity and effects on lung function. Journal of Applied Physiology, 108(1), 206-11. [More Information]
  • Brown, N., Xuan, W., Salome, C., Berend, N., Hunter, M., Musk, A., James, A., King, G. (2010). Reference equations for respiratory system resistance and reactance in adults. Respiratory Physiology and Neurobiology, 172(3), 162-168. [More Information]
  • King, G., Harris, B., Mahadev, S. (2010). V/Q SPECT: Utility for Investigation of Pulmonary Physiology. Seminars in Nuclear Medicine, 40(6), 467-473. [More Information]

2009

  • Chapman, D., Berend, N., King, G., McParland, B., Salome, C. (2009). Deep inspirations protect against airway closure in nonasthmatic subjects. Journal of Applied Physiology, 107(2), 564-569. [More Information]
  • Deng, L., Bosse, Y., Brown, N., Chin, L., Connolly, S., Fairbank, N., King, G., Maksym, G., Pare, P., Seow, C., et al (2009). Stress and strain in the contractile and cytoskeletal filaments of airway smooth muscle. Pulmonary Pharmacology and Therapeutics, 22(5), 407-416. [More Information]

2008

  • Harris, B., Bailey, D., Roach, P., Schembri, G., Ho Shon, I., Chicco, P., Bailey, E., King, G. (2008). A clinical comparison between traditional planar V/Q images and planar images generated from SPECT V/Q scintigraphy. Nuclear Medicine Communications, 29(4), 323-330. [More Information]
  • Chapman, D., Berend, N., King, G., Salome, C. (2008). Increased airway closure is a determinant of airway hyperresponsiveness. European Respiratory Journal, 32(6), 1563-1569. [More Information]
  • Berend, N., Salome, C., King, G. (2008). Mechanisms of airway hyperresponsiveness in asthma. Respirology, 13(5), 624-631. [More Information]
  • Harris, B., Bailey, D., Chicco, P., Bailey, E., Roach, P., King, G. (2008). Objective analysis of whole lung and lobar ventilation/perfusion relationships in pulmonary embolism. Clinical Physiology and Functional Imaging, 28(1), 14-26. [More Information]
  • Lahzami, S., King, G. (2008). Targeting small airways in asthma: the new challenge of inhaled corticosteroid treatment. The European Respiratory Journal, 31(6), 1145-7. [More Information]

2007

  • Brown, N., Salome, C., Berend, N., Thorpe, C., King, G. (2007). Airway distensibility in adults with asthma and healthy adults, measured by forced oscillation technique. American Journal of Respiratory and Critical Care Medicine, 176(2), 129-137. [More Information]
  • An, S., Bai, T., Bates, J., Black, J., Brown, R., Brusasco, V., Chitano, P., Deng, L., King, G., McParland, B., et al (2007). Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. European Respiratory Journal, 29(5), 834-860. [More Information]
  • Thompson, B., King, G., Harding, R. (2007). Commentary on The role of the large airways on smooth muscle contraction in asthma".". Journal of Applied Physiology, 103(4), 1465; author reply 1466. [More Information]
  • Borger, P., Matsumoto, H., Boustany, S., Gencay, M., Burgess, J., King, G., Black, J., Tamm, M., Roth, M. (2007). Disease-specific expression and regulation of CCAAT/enhancer-binding proteins in asthma and chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology. [More Information]
  • Salome, C., Munoz, P., Berend, N., Thorpe, C., Schachter, L., King, G. (2007). Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. International Journal of Obesity, online, 1-8. [More Information]
  • Harris, B., Bailey, D., Roach, P., Bailey, E., King, G. (2007). Fusion imaging of computed tomographic pulmonary angiography and SPECT ventilation/perfusion scintigraphy: initial experience and potential benefit. European Journal of Nuclear Medicine and Molecular Imaging, 34(1), 135-142. [More Information]
  • Harris, B., Bailey, D., Miles, S., Bailey, E., Rogers, K., Roach, P., Thomas, P., Hensley, M., King, G. (2007). Objective analysis of tomographic ventilation-perfusion scintigraphy in pulmonary embolism. American Journal of Respiratory and Critical Care Medicine, 175(11), 1173-1180. [More Information]
  • Diba, C., Salome, C., Reddel, H., Thorpe, C., Toelle, B., King, G. (2007). Short-term variability of airway caliber - a marker of asthma? Journal of Applied Physiology, 103(1), 296-304. [More Information]

2006

  • King, G., Salome, C. (2006). Multimodality measurements of small airways disease. European Respiratory Journal, 27(2), 250-252. [More Information]
  • Harris, B., Bailey, D., Roach, P., Marshman, D., McElduff, A., King, G. (2006). Use of Fusion Imaging to Localize an Ectopic Thoracic Parathyroid Adenoma. The Annals of Thoracic Surgery, 82. [More Information]

2005

  • Ko, F., Diba, C., Roth, M., McKay, K., Johnson, P., Salome, C., King, G. (2005). A comparison of airway and serum matrix metalloproteinase-9 activity among normal subjects, asthmatic patients, and patients with asthmatic mucus hypersecretion. Chest, 127(6), 1919-1927. [More Information]
  • Coxson, H., Baile, E., King, G., Mayo, J. (2005). Diagnosis of subsegmental pulmonary emboli: a multi-center study using a porcine model. Journal of thoracic imaging, 20(1), 24-31. [More Information]
  • King, G., Downie, S., Verbanck, S., Thorpe, C., Berend, N., Salome, C., Thompson, B. (2005). Effects of methacholine on small airway function measured by forced oscillation technique and multiple breath nitrogen washout in normal subjects. Respiratory Physiology and Neurobiology, 148(01-Feb), 165-177. [More Information]
  • King, G., Brown, N., Diba, C., Thorpe, C., Munoz, P., Marks, G., Toelle, B., Ng, K., Berend, N., Salome, C. (2005). The effects of body weight on airway calibre. European Respiratory Journal, 25(5), 896-901. [More Information]

2004

  • Berend, N., Salome, C., Thompson, B., Brown, N., Thorpe, C., Verbanck, S., Downie, S., King, G. (2004). A Comparison Of Two Methods For Measuring Airway Distensibility: Nitrogen Washout And The Forced Oscillation Technique. Physiological Measurement, 25(4), 1067-1075.
  • Roth, M., Johnson, P., Borger, P., Bihl, M., Rudiger, J., King, G., Ge, Q., Hostettler, K., Burgess, J., Black, J., et al (2004). Dysfunctional Interaction Of C/EBPα And The Glucocorticoid Receptor In Asthmatic Bronchial Smooth-Muscle Cells. New England Journal of Medicine, 351(6), 560-574.
  • King, G., Carroll, J., Muller, N., Whittall, K., Gao, M., Nakano, Y., Pare, P. (2004). Heterogeneity Of Narrowing In Normal And Asthmatic Airways Measured By Hrct. European Respiratory Journal, 24(2), 211-218.
  • Thorpe, C., Salome, C., Berend, N., King, G. (2004). Modeling Airway Resistance Dynamics After Tidal And Deep Inspirations. Journal of Applied Physiology, 97(5), 1643-1653.

2003

  • Salome, C., Thorpe, C., Diba, C., Brown, N., Berend, N., King, G. (2003). Airway re-narrowing following deep inspiration in asthmatic and nonasthmatic subjects. European Respiratory Journal, 22, 62-68.
  • Burgess, J., Johnson, P., Ge, Q., Au, W., Poniris, M., McParland, B., King, G., Roth, M., Black, J. (2003). Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 167(1), 71-77.

2002

  • Roth, M., Johnson, P., Rudiger, J., King, G., Ge, Q., Burgess, J., Anderson, G., Tamm, M., Black, J. (2002). Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. The Lancet, 360(9342), 1293-1299.
  • Nakano, Y., Muller, N., King, G., Niimi, A., Kalloger, S., Mishima, M., Pare, P. (2002). Quantitative assessment of airway remodeling using high-resolution CT. Chest, 122(6 Supplement), 271S-275S.
  • Crossley, M., King, G., Pyke, S., Tansey, C. (2002). Reaction of 5-nitro-octaethylporphyrins with nucleophiles. Journal of Porphyrins and Phthalocyanines, 6(11), 685-694.

2001

  • Blair, D., Bennett, M., King, G., Robson, S. (2001). Vesicle-associated proteins and transmitter release from sympathetic ganglionic boutons. NeuroReport, 12, 607-610.

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