Dr Harriet Gee

Clinical Senior Lecturer
Medicine, Central Clinical School

Telephone +61 2

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Biographical details

Dr Harriet Gee is a translational researcher and Advanced Trainee in Radiation Oncology at Royal Prince Alfred Hospital. She graduated with an MBBS from the University of Melbourne, receiving the AMA Prize for the student with the highest overall mark. After basic medical training at Royal Melbourne Hospital, Dr Gee undertook a DPhil (PhD-equivalent) with Professor Adrian Harris at the University of Oxford as a Rhodes Scholar. Her research has been published in leading journals including Nature, Cancer, and Clinical Cancer Research, and focuses on biomarkers of radiation resistance.

Research interests

microRNAs, hypoxia, biomarkers, radiotherapy, radiation resistance

Teaching and supervision

Sydney University Medical Students (Oncology Block); co-supervision of Honours student

International links

United Kingdom

(University of Oxford) Use of microRNAs and their target genes as markers of hypoxia and radiation resistance

United States

(Indiana University) Use of small non-coding RNAs and related genes as markers of hypoxia and radiation resistance

Selected publications

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Journals

  • Gee, H., Bignell, F., Odgers, D., Gill, S., Martin, D., Toohey, J., Carroll, S. (2016). In vivo dosimetric impact of breast tissue expanders on post-mastectomy radiotherapy. Journal of Medical Imaging and Radiation Oncology, 60(1), 138-145. [More Information]
  • Gee, H., Buffa, F., Harris, A., Toohey, J., Carroll, S., Cooper, C., Beith, J., McNeil, C., Carmalt, H., Mak, C., Kennedy, C., O'Toole, S., et al (2015). MicroRNA-Related DNA repair/ cell-cycle genes independently associated with relapse after radiation therapy for early breast cancer. International Journal of Radiation Oncology: Biology Physics, 93(5), 1104-1114. [More Information]
  • Gee, H., Ivan, C., Calin, G., Ivan, M. (2014). HypoxamiRs and Cancer: From Biology to Targeted Therapy. Antioxidants & Redox Signaling, 21(8), 1220-1238. [More Information]
  • Kumar, K., Wigfield, S., Gee, H., Devlin, C., Singleton, D., Li, J., Buffa, F., Huffman, M., Sinn, A., Silver, J., et al (2013). Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine, 91, 749-758. [More Information]
  • Gee, H., Hruby, G. (2012). Update on the Management of Merkel Cell Carcinoma. Cancer Forum, 36(3), 1-5.
  • Buffa, F., Camps, C., Winchester, L., Snell, C., Gee, H., Sheldon, H., Taylor, M., Harris, A., Ragoussis, J. (2011). microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Research, 71(17), 5635-5645. [More Information]
  • Gee, H., Buffa, F., Camps, C., Ramachandran, A., Leek, R., Taylor, M., Patil, M., Sheldon, H., Betts, G., Homer, J., et al (2011). The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis. British Journal of Cancer, 104(7), 1168-1177. [More Information]
  • Gee, H., Camps, C., Buffa, F., Patiar, S., Winter, S., Betts, G., Homer, J., Corbridge, R., Cox, G., West, C., et al (2010). hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer, 116(9), 2148-2158. [More Information]
  • Favaro, E., Ramachandran, A., McCormick, R., Gee, H., Blancher, C., Crosby, M., Devlin, C., Blick, C., Buffa, F., Li, J., et al (2010). MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PloS One, 5(4), 1-11. [More Information]
  • Gee, H., Camps, C., Buffa, F., Colella, S., Sheldon, H., Gleadle, J., Ragoussis, J., Harris, A. (2008). MicroRNA-10b and breast cancer metastasis. Nature, 455(7216), E8-E9. [More Information]

2016

  • Gee, H., Bignell, F., Odgers, D., Gill, S., Martin, D., Toohey, J., Carroll, S. (2016). In vivo dosimetric impact of breast tissue expanders on post-mastectomy radiotherapy. Journal of Medical Imaging and Radiation Oncology, 60(1), 138-145. [More Information]

2015

  • Gee, H., Buffa, F., Harris, A., Toohey, J., Carroll, S., Cooper, C., Beith, J., McNeil, C., Carmalt, H., Mak, C., Kennedy, C., O'Toole, S., et al (2015). MicroRNA-Related DNA repair/ cell-cycle genes independently associated with relapse after radiation therapy for early breast cancer. International Journal of Radiation Oncology: Biology Physics, 93(5), 1104-1114. [More Information]

2014

  • Gee, H., Ivan, C., Calin, G., Ivan, M. (2014). HypoxamiRs and Cancer: From Biology to Targeted Therapy. Antioxidants & Redox Signaling, 21(8), 1220-1238. [More Information]

2013

  • Kumar, K., Wigfield, S., Gee, H., Devlin, C., Singleton, D., Li, J., Buffa, F., Huffman, M., Sinn, A., Silver, J., et al (2013). Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine, 91, 749-758. [More Information]

2012

  • Gee, H., Hruby, G. (2012). Update on the Management of Merkel Cell Carcinoma. Cancer Forum, 36(3), 1-5.

2011

  • Buffa, F., Camps, C., Winchester, L., Snell, C., Gee, H., Sheldon, H., Taylor, M., Harris, A., Ragoussis, J. (2011). microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Research, 71(17), 5635-5645. [More Information]
  • Gee, H., Buffa, F., Camps, C., Ramachandran, A., Leek, R., Taylor, M., Patil, M., Sheldon, H., Betts, G., Homer, J., et al (2011). The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis. British Journal of Cancer, 104(7), 1168-1177. [More Information]

2010

  • Gee, H., Camps, C., Buffa, F., Patiar, S., Winter, S., Betts, G., Homer, J., Corbridge, R., Cox, G., West, C., et al (2010). hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer, 116(9), 2148-2158. [More Information]
  • Favaro, E., Ramachandran, A., McCormick, R., Gee, H., Blancher, C., Crosby, M., Devlin, C., Blick, C., Buffa, F., Li, J., et al (2010). MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PloS One, 5(4), 1-11. [More Information]

2008

  • Gee, H., Camps, C., Buffa, F., Colella, S., Sheldon, H., Gleadle, J., Ragoussis, J., Harris, A. (2008). MicroRNA-10b and breast cancer metastasis. Nature, 455(7216), E8-E9. [More Information]

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