Dr Helen Ritchie

Senior Lecturer
Biomedical Sciences, School of Medical Sciences

Telephone +61 2 9351 9476
Fax +61 2 9351 9715

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Research interests

Dr Helen Ritchie is a developmental toxicologist with a special interest in the effects of vitamin A, herbal medicine and cardiovascular medicines on the developing embryo and fetus.

International links

Sweden

(Uppsala University) Mats Nilsson; The effect of cardiovascular ion channel blockers on the developing embryonic heart.

Selected grants

2014

  • The role of foetal hypoxia and hyperglycaemia in the formation of cleft lip maxillary hypoplasia; Howe A, Ritchie H, Webster W; Australian Dental Research Foundation/Research Support.

2009

  • The role of foetal hypoxia in cleft lip and maxillary hypoplasia; Howe A, Oakes D, Webster W, Ritchie H; Australian Dental Research Foundation/Research Support.
  • Prenatal facial development and the role of oxygen; Oakes D, Ritchie H, Webster W, Howe A; Dental Board of NSW/Research Support.

2003

  • Peri-conceptual use of folic acid, multivitamins and herbal products in women of mixed ethnic background; Kennedy C, Ritchie H; Royal Hospital for Women (part of South Eastern Sydney Area Health Services)/Randwick Foundation Grant.

2000

  • The role of herbicides and other chemicals in causing male-mediated developmental toxicity; Webster W, Pollak J, Woodman P, Ritchie H; Veterans Affairs/Health and Medical Research Grants.
  • Risk of adverse reproductive outcome following exposure to a herbal remedy in the pregnant rat; Ritchie H; University of Sydney/Internal Research Grant Allocations.

Selected publications

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Journals

  • Nilsson, M., Ritchie, H., Webster, W. (2013). The effect on rat embryonic heart rate of Na+, K+, and Ca2+ channel blockers, and the human teratogen phenytoin, changes with gestational age. Birth Defects Research (Part B), 98(5), 416-427. [More Information]
  • Ritchie, H., Ababneh, D., Oakes, D., Power, C., Webster, W. (2013). The teratogenic effect of dofetilide during rat limb development and association with drug-induced bradycardia and hypoxia in the embryo. Birth Defects Research (Part B), 98(2), 144-153. [More Information]
  • Ababneh, D., Ritchie, H., Webster, W. (2012). Antidepressants Cause Bradycardia and Heart Block in GD 13 Rat Embryos In Vitro. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 95(2), 184-193. [More Information]
  • Gunnstrom, M., Ababneh, D., Webster, W., Oakes, D., Ritchie, H. (2012). Antipsychotic drugs cause bradycardia in GD 13 rat embryos in vitro. Reproductive Toxicology, 34(3), 443-450. [More Information]
  • Abela, D., Ritchie, H., Ababneh, D., Gavin, C., Nilsson, M., Khan, M., Carlsson, K., Webster, W. (2010). The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 89(5), 429-440. [More Information]
  • Oakes, D., Ritchie, H., Woodman, P., Narup, E., Moscova, M., Picker, K., Webster, W. (2009). Genotoxicity studies of a desealant solvent mixture, SR-51. Toxicology and Industrial Health: An International Journal, 25(1), 5-13. [More Information]
  • Yao, M., Ritchie, H., Brown-Woodman, P. (2008). A reproductive screening test of hawthorn. Journal of Ethnopharmacology, 118, 127-132. [More Information]
  • Warner, R., Ritchie, H., Woodman, P., Oakes, D., Pourghasem, M. (2008). The effect of prenatal exposure to a repeat high dose of toluene in the fetal rat. Reproductive Toxicology, 26, 267-272. [More Information]
  • Yao, M., Ritchie, H., Woodman, P. (2007). A developmental toxicity-screening test of valerian. Journal of Ethnopharmacology, 113(2), 204-209. [More Information]
  • Yao, M., Ritchie, H., Woodman, P. (2006). A reproductive screening test of feverfew. Is a full reproductive study warranted? Reproductive Toxicology, 22(4), 688-693. [More Information]
  • Yao, M., Ritchie, H., Woodman, P. (2005). A reproductive screening test of goldenseal. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 74(5), 399-404. [More Information]
  • Woodman, P., Ritchie, H., Korabelnikoff, A., Emmanuel, C. (2004). Replacement Of Ether With Alternate Volatile Anesthetics For Collection Of Rat Serum Used In Embryo Culture. Toxicology in Vitro, 18(5), 719-724.
  • Ritchie, H., Woodman, P., Korabelnikoff, A. (2003). Effect of Co-Administration of Retinoids on Rat Embryo Development In Vitro. Birth Defects Research. Part A: Clinical and Molecular Teratology, 67(6), 444-451. [More Information]
  • Boswell-Ruys, C., Ritchie, H., Woodman, P. (2003). Preliminary screening study of reproductive outcomes after exposure to yarrow in the pregnant rat. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 68(5), 416-420. [More Information]
  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). A Study of the Potential for a Herbicide Formulation Containing 2,4-D and Picloram to Cause Male-Mediated Developmental Toxicity in Rats. Toxicological Sciences, 68(1), 200-206.
  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). Testicular changes induced by chronic exposure to the herbicide formulation, Tordon 75D(R) (2,4-dichlorophenoxyacetic acid and picloram)in rats. Reproductive Toxicology, 16(3), 281-289.

Conferences

  • Ritchie, H., Stuart, M., Baguley, J. (2005). Meeting the challenge of using grade descriptors and multiple choice assessment tests in an inter-professional group of students. 3rd EdHealth Conference 2005.
  • Yao, M., Woodman, P., Ritchie, H. (2002). Do the herbal remedies - feverfew and valerian have an adverse effect on pregnancy outcome in the rat? Third Research Conference 2002 "from cell to society 3", : British Medical Journal Publishing Group.
  • Yao, M., Woodman, P., Ritchie, H. (2001). Do herbal remedies have an adverse effect on pregnancy outcome in the rat? Australian Birth Defects Society, : World Scientific Publishing.
  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2001). Male mediated developmental toxicity and the herbicide formulation, Tordon 75D. Australian Birth Defects Society, : World Scientific Publishing.

2013

  • Nilsson, M., Ritchie, H., Webster, W. (2013). The effect on rat embryonic heart rate of Na+, K+, and Ca2+ channel blockers, and the human teratogen phenytoin, changes with gestational age. Birth Defects Research (Part B), 98(5), 416-427. [More Information]
  • Ritchie, H., Ababneh, D., Oakes, D., Power, C., Webster, W. (2013). The teratogenic effect of dofetilide during rat limb development and association with drug-induced bradycardia and hypoxia in the embryo. Birth Defects Research (Part B), 98(2), 144-153. [More Information]

2012

  • Ababneh, D., Ritchie, H., Webster, W. (2012). Antidepressants Cause Bradycardia and Heart Block in GD 13 Rat Embryos In Vitro. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 95(2), 184-193. [More Information]
  • Gunnstrom, M., Ababneh, D., Webster, W., Oakes, D., Ritchie, H. (2012). Antipsychotic drugs cause bradycardia in GD 13 rat embryos in vitro. Reproductive Toxicology, 34(3), 443-450. [More Information]

2010

  • Abela, D., Ritchie, H., Ababneh, D., Gavin, C., Nilsson, M., Khan, M., Carlsson, K., Webster, W. (2010). The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 89(5), 429-440. [More Information]

2009

  • Oakes, D., Ritchie, H., Woodman, P., Narup, E., Moscova, M., Picker, K., Webster, W. (2009). Genotoxicity studies of a desealant solvent mixture, SR-51. Toxicology and Industrial Health: An International Journal, 25(1), 5-13. [More Information]

2008

  • Yao, M., Ritchie, H., Brown-Woodman, P. (2008). A reproductive screening test of hawthorn. Journal of Ethnopharmacology, 118, 127-132. [More Information]
  • Warner, R., Ritchie, H., Woodman, P., Oakes, D., Pourghasem, M. (2008). The effect of prenatal exposure to a repeat high dose of toluene in the fetal rat. Reproductive Toxicology, 26, 267-272. [More Information]

2007

  • Yao, M., Ritchie, H., Woodman, P. (2007). A developmental toxicity-screening test of valerian. Journal of Ethnopharmacology, 113(2), 204-209. [More Information]

2006

  • Yao, M., Ritchie, H., Woodman, P. (2006). A reproductive screening test of feverfew. Is a full reproductive study warranted? Reproductive Toxicology, 22(4), 688-693. [More Information]

2005

  • Yao, M., Ritchie, H., Woodman, P. (2005). A reproductive screening test of goldenseal. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 74(5), 399-404. [More Information]
  • Ritchie, H., Stuart, M., Baguley, J. (2005). Meeting the challenge of using grade descriptors and multiple choice assessment tests in an inter-professional group of students. 3rd EdHealth Conference 2005.

2004

  • Woodman, P., Ritchie, H., Korabelnikoff, A., Emmanuel, C. (2004). Replacement Of Ether With Alternate Volatile Anesthetics For Collection Of Rat Serum Used In Embryo Culture. Toxicology in Vitro, 18(5), 719-724.

2003

  • Ritchie, H., Woodman, P., Korabelnikoff, A. (2003). Effect of Co-Administration of Retinoids on Rat Embryo Development In Vitro. Birth Defects Research. Part A: Clinical and Molecular Teratology, 67(6), 444-451. [More Information]
  • Boswell-Ruys, C., Ritchie, H., Woodman, P. (2003). Preliminary screening study of reproductive outcomes after exposure to yarrow in the pregnant rat. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 68(5), 416-420. [More Information]

2002

  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). A Study of the Potential for a Herbicide Formulation Containing 2,4-D and Picloram to Cause Male-Mediated Developmental Toxicity in Rats. Toxicological Sciences, 68(1), 200-206.
  • Yao, M., Woodman, P., Ritchie, H. (2002). Do the herbal remedies - feverfew and valerian have an adverse effect on pregnancy outcome in the rat? Third Research Conference 2002 "from cell to society 3", : British Medical Journal Publishing Group.
  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). Testicular changes induced by chronic exposure to the herbicide formulation, Tordon 75D(R) (2,4-dichlorophenoxyacetic acid and picloram)in rats. Reproductive Toxicology, 16(3), 281-289.

2001

  • Yao, M., Woodman, P., Ritchie, H. (2001). Do herbal remedies have an adverse effect on pregnancy outcome in the rat? Australian Birth Defects Society, : World Scientific Publishing.
  • Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2001). Male mediated developmental toxicity and the herbicide formulation, Tordon 75D. Australian Birth Defects Society, : World Scientific Publishing.

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