Associate Professor Hong Zhou
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Principal Research Fellow
C22 - Concord Hospital |
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Themes | Research interests | Grants | PhD & Masters' project opportunities | Keywords | International links
Research interests
I have a long-standing track record in basic research into bone biology. I have extensive experience in bone cell and molecular biology and in the use and analysis of animal models of bone disease, including transgenic, fracture healing and cancer models. My major scientific interests include effects of glucocorticoids on bone. I have made significant discoveries how glucocorticoids, through the osteoblast, regulate mesenchymal stem cell commitment and skeletal development in mice; fund that glucocorticoid signalling in osteoblasts up-regulates autoimmune arthritis in vivo and disrupting GC-signaling in osteoblasts protects mice against both the bone-wasting and diabetogenic effects of pharmacological GC doses.
Current national competitive grants*
2010
The role of endogenous glucocorticoids in Autoimmune Arthritis
Zhou H, Seibel M, Stewart P, Buttgereit F, Cooper M
NHMRC Project Grant ($662,600 over 4 years)
The Role of the Osteoblast in Mediating Glucocorticoid-induced Metabolic Dysfunction
Seibel M, Zhou H, Gundberg C, Dunstan C
NHMRC Project Grant ($788,900 over 4 years)
Role of Lamin A/C in Osteoblastogenesis and Age-related Bone Loss
Duque G, Zhou H, Drissi H, Li W
NHMRC Project Grant ($458,550 over 3 years)
* Grants administered through the University of Sydney
PhD and Masters' project opportunities
The Role of the Osteoblast in Mediating Glucocorticoid-Induced Metabolic Dysfunction
Glucocorticoid effects on bone: The role of the osteoblast
The Role of Endogenous Glucocorticoids in Autoimmune Arthritis
International links
Germany. (Humboldt University Berlin,) collaborate with Prof. Frank Buttgereit-Role of glucocorticoids in autoimmune arthritis.
United States. (University of Rochester, NY.) Co-investigator Prof. Di Chen-HNMRC Project Grant on How Osteoblasts Control Mesenchymal Progenitors..
United Kingdom. (University of Birmingham) Collaborate with Prof Paul Stewart and Dr Mark Cooper - Role of 11ß-HSD1 in inflammatory arthritis.