Professor Iain L. Campbell
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Head of School and Chair, Molecular Biology
G08 - Biochemistry Building |
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Themes | Research interests | Grants | PhD & Masters' project opportunities | Honours project opportunities | Keywords | International links
Research interests
Inflammatory responses are regulated by hormone-like proteins called cytokines. Such responses may contribute to gross structural and functional alterations in the central nervous system (CNS) in a variety of debilitating neurological disorders, for example, multiple sclerosis, stroke and infectious disease. The overall goal of our research is to advance understanding of the basic molecular mechanisms that control inflammatory processes in the CNS.
Ultimately the information derived from our studies could identify key molecular substrates of cytokine action that could serve as rational targets for the development and testing of novel therapeutic strategies.
We gratefully acknowledge the support of our research program by NIH Grants MH62231; NS036979; NS044905 and a NSW Spinal Cord Injury and Related Neurological Conditions Research Grant.
Current national competitive grants*
2011
Role of IRF8 in central nervous system glial cell function
Campbell I
NHMRC Project Grant ($414,615 over 3 years)
2010
Interleukin-6 /gp130 signaling and actions in the CNS
Campbell I
NHMRC Project Grant ($529,500 over 3 years)
* Grants administered through the University of Sydney
PhD and Masters' project opportunities
Molecular and cellular mechanisms in neuroinflammatory disease
Honours project opportunities
Changes in gene expression in neurons and microglia in WNV encephalitis
Infiltrating leukocytes in WNV encephalitis - their role in mortality
International links
Spain. (Professors Castellano, Gonzalez and Hidalgo,
Autonomous University of Barcelona) Research collaboration studying the mechanisms of IL-6-induced inflammation and injury in the central nervous system.
Germany. (Professors Rose-John and Scheller, University of Kiel) Research collaboration investigating IL-6 trans-signalling in central nervous system inflammation and injury.