Professor Iain L. Campbell

Head of School and Chair, Molecular Biology
School of Molecular Bioscience

G08 - Biochemistry Building
The University of Sydney
NSW 2006 Australia

T: +61 2 9351 4676
F: +61 2 9351 5858
W: Related website

Biographical details

Iain Campbell grew up in Dee Why on the northern beaches of Sydney, Australia and obtained his graduate (1979) and doctoral (1982) degrees in Science from the University of Sydney. After a short postdoctoral period in Britain and Sweden, Iain returned to the Royal Melbourne Hospital in 1982 and then moved to the Walter and Eliza Hall Institute in 1985. In 1989, he left Australia’s shores to do a sabbatical at the Scripps Research Institute in San Diego, USA and that is where he remained for over 14 years as a US National Institutes of Health (NIH)-funded biomedical research scientist and a Professor in the Department of Neuropharmacology. In January of 2004, Iain returned to Australia to take on a new challenge as Chair of Molecular Biology within the School of Molecular Bioscience at the University of Sydney.

Research interests

The overall goal of our research is to understand the molecular and cellular basis of host defense and immunoinflammatory processes that contribute to disease in the central nervous system. During my time at Scripps our research was responsible for the development of a number of unique functional genomics approaches including the generation of novel transgenicmodeling strategies to express key proinflammatory and anti-microbial cytokine genes specifically in astrocytes in the CNS. The results of this research have considerably advanced knowledge of the causal role of cytokines and chemokines in inflammation and neurological disease and unraveled key mechanisms that control how these potent biological response modifiers communicate in the CNS to modulate cellular function and how this translates into altered behavior. Since relocating to Sydney and with the support of NIH and NHMRC funding the focus of our work has continued in this area.

International links

Spain. (Professors Castellano, Gonzalez and Hidalgo, Autonomous University of Barcelona) Research collaboration studying the mechanisms of IL-6-induced inflammation and injury in the central nervous system.
Germany. (Professors Rose-John and Scheller, University of Kiel) Research collaboration investigating IL-6 trans-signalling in central nervous system inflammation and injury.