Dr Imre Hunyor

MBBS(Hons) BSc(Adv) DPhil(Oxon) FRACP
Cardiologist
Network Director of Physician Training (RPA)
Clinical Senior Lecturer
Central Clinical School


Website RPA Basic Physician Training Network
RPA Basic Physician Training Revision Course

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Biographical details

Dr Imre Hunyor completed his medical degree with Honours at the University of Sydney following a degree in Advanced Science. He completed his doctorate at the University of Oxford as a Rhodes Scholar under the supervision of Professor Stefan Neubauer in the department of Cardiovascular Medicine, based at the Wellcome Trust Centre for Human Genetics and the Oxford Centre for Clinical Magnetic Resonance Research. During his doctoral work titled “Modulation of Mitochondrial Creatine Kinase and its Effect on Cardiac Energetics”, he created and phenotyped transgenic models to understand pathways important in cardiac metabolism. He is experienced in molecular biology, HPLC, immunohistochemistry, Langendorff perfusion, small animal cardiac high-field magnetic resonance spectroscopy (31P MRS) and cine imaging. His doctoral research focused on mechanisms of impaired energetics leading to heart failure.

His subsequent postgraduate training in Cardiology and subspecialty training in Cardiac Imaging was at the Royal Prince Alfred Hospital. Dr Hunyor's primary clinical and research interests include the application of novel imaging methods to help with the early detection and monitoring of cardiac disease. He developed an interest in cardiac imaging as a powerful tool to non-invasively interrogate the heart's structure, function and biochemistry. He is experienced in all aspects of multimodal cardiac imaging including echocardiography (TOE & TTE), CT coronary angiography and Cardiac MRI. All modalities are utilised for active clinical research projects.

Dr Hunyor is a Staff Specialist Cardiologist and also the Network Director of Physician Training at the Royal Prince Alfred Hospital. He oversees the training programme for Basic Physician Trainees and is an examiner for the FRACP.

Research interests

Multimodal cardiac imaging (echocardiography, CTCA, MRI)

Cardiac energetics

Hypoxia

Teaching and supervision

Medical Students: Stage I Cardiology Block teaching (Bedside tutorials, TBL coordinator and lectures in Electrocardiography).

Cardiac Imaging - Training & Supervision of Registrars and Fellows in Echocardiography, Cardiac CT and Cardiac MRI

Physician Training/Clinical Teaching

Current projects

Right ventricular responses to exercise and stress in pulmonary hypertension; pathophysiology and impact on prognosis

Associations

Royal Australasian College of Physicians

Society for Cardiovascular Magnetic Resonance (SCMR)

International Society for Heart Research (ISHR)

American College of Cardiology

Awards and honours

Rhodes Scholarship

In the media

Selected stories about the BPTOK programme for Physician Wellbeing at RPA:

Doctors are Human Too (New York Times)

AMA calls for national focus on doctors mental health(ABC News)

RPAs BPTOK Program Supports Junior Doctors Mental and Physical Wellbeing(Sydney Morning Herald)

In Press

Hunyor, I.,Cook., K. Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer, AJP: Regulatory, Integrative and Comparative Physiology, (2018) Jul.https://doi.org/10.1152/ajpregu.00036.2018[Epub ahead of print].

Selected previous publications (prior to 2016 - for more recent see below)

Hunyor, I.,Abed, HS., Sy, RW., Hodkinson, EC., Santucci, P., McGuire, MA. Intermittent failure of pacing output caused by algorithm to prevent T-wave oversensing. HeartRhythm Case Reports. (2016) vol 2 (4) pp. 286–289.DOI:http://dx.doi.org/10.1016/j.hrcr.2016.01.003

Lygate, C., Aksentijevic, D., Dawson, D., ten Hove, M., Phillips, W., Medway, D., Sebag-Montefiore, L.,Hunyor, I., Channon, K., Clarke, K., Zervou, S., Watkins, H., Balaban, B., Neubauer, S. Living Without Creatine: Unchanged Exercise Capacity and Response to Chronic Myocardial Infarction in Creatine-Deficient Mice. Circulation Research (2013) vol 112 (6) 945-55.

Lygate, C., Medway, D., Ostrowski, P., Aksentijevic, D., Sebag-Montefiore, L.,Hunyor, I.,Zervou, S., Weiringa, B., Schneider, J., Neubauer, S.Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background,gender and age. Basic Research Cardiology, (2012) vol 107 (5) 276.

Lygate, C.,Hunyor, I., Medway, D., de Bono, J., Dawson, D., Wallis, J., Sebag-Montefiore, L., Neubauer, S. Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background. J Mol Cell Cardiol (2009) vol. 46 (1) pp. 93-9.

ten Hove, M., Makinen, K., Sebag-Montefiore, L.,Hunyor, I., Fischer, A., Wallis, J., Isbrandt, D., Lygate C., Neubauer, S. Creatine uptake in mouse hearts with genetically altered creatine levels. J Mol Cell Cardiol (2008) vol. 45 (3) pp. 453-9.

Selected publications

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Journals

  • Sasson, S., Russo, R., Chung, T., Chu, G., Hunyor, I., Williamson, J., Murad, A., Kane, A., Riminton, S., Limaye, S. (2017). Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by [supersript 18]F-fluorodeoxyglucose-positron emission tomography: Two case reports and a review of the literature. Journal of Medical Case Reports, 11(1), 1-9. [More Information]
  • Martin, S., Ingles, J., Hunyor, I., Bagnall, R., Puranik, R., Semsarian, C. (2017). LAMP2 shines a light on cardiomyopathy in an athlete. HeartRhythm Case Reports, 3(3), 172-176. [More Information]

2017

  • Sasson, S., Russo, R., Chung, T., Chu, G., Hunyor, I., Williamson, J., Murad, A., Kane, A., Riminton, S., Limaye, S. (2017). Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by [supersript 18]F-fluorodeoxyglucose-positron emission tomography: Two case reports and a review of the literature. Journal of Medical Case Reports, 11(1), 1-9. [More Information]
  • Martin, S., Ingles, J., Hunyor, I., Bagnall, R., Puranik, R., Semsarian, C. (2017). LAMP2 shines a light on cardiomyopathy in an athlete. HeartRhythm Case Reports, 3(3), 172-176. [More Information]

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