Professor Jack Wall

Professor of Medicine
Medicine, Nepean Clinical School

Telephone +61 2 4734 2604
Fax +61 2 4734 2614

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Selected grants

2014

  • Thyretain TSI in Euthyroid Graves' Disease; Wall J, Lahooti H; Nepean Medical Research Foundation/Project Grant.

2013

  • Risk factors for ophthalmopathy determined using a human pregnancy model; Wall J, Lahooti H; Australian Women and Children's Research Foundation (OZWAC)/Medical Research Project Grant.

2010

  • Effect of pregnancy on eyes changes associated with Graves hyperthyroidism and Hashimotos thyroidism; Champion B, Wall J; Australian Women and Children's Research Foundation (OZWAC)/Medical Research Project Grant.

2008

  • Significance of new anti-bodies associted with thyroid eye disease; Wall J; University of Sydney/Internal Scheme.

2006

  • Rebecca Cooper Medical Research Foundation - Research Grants Program; Wall J; Rebecca Cooper Medical Research Foundation/Rebecca Cooper Medical Research Foundation.

Selected publications

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Book Chapters

  • Wall, J., Champion, B. (2012). The Role of Real-Time Thyroid Ultrasonography in the Assessment and Management of Patients with Hashimoto's Thyroiditis. In Drahomira Springer (Eds.), Hypothyroidism – Influences and Treatments, (pp. 167-180). Croatia: InTech Publishers.

Journals

  • Gopinath, B., Harris, D., Wall, J., Kifley, A., Mitchell, P. (2013). Relationship between thyroid dysfunction and chronic kidney disease in community-dwelling older adults. Maturitas, 75(2), 159-164. [More Information]
  • Nguyen, B., Gopinath, B., Ma, G., Champion, B., Wall, J. (2012). Cell mediated Immunity Against Three Eye Muscle Antigens and Correlation with Eye Signs in Patients with Transient and Chronic Thyroiditis. The Open Autoimmunity Journal, 4, 4-9.
  • Ardley, M., McCorquodale, T., Lahooti, H., Champion, B., Wall, J. (2012). Eye findings and immunological markers in probands and their euthyroid relatives from a single family with multiple cases of thyroid autoimmunity. Thyroid Research, 5(1), 1-6. [More Information]
  • McCorquodale, T., Lahooti, H., Gopinath, B., Wall, J. (2012). Long-term follow-up of seven patients with ophthalmopathy not associated with thyroid autoimmunity: heterogeneity of autoimmune ophthalmopathy. Clinical Ophthalmology, 6, 1063-1071. [More Information]
  • El-Kaissi, S., Wall, J. (2012). Targeting the thyrotropin receptor in thyroid disease. Expert Opinion on Therapeutic Targets, 16(7), 719-727. [More Information]
  • De Bellis, A., Conzo, G., Cennamo, G., Pane, E., Bellastella, G., Colella, C., Dello Iacovo, A., Paglionico, V., Sinisi, A., Wall, J., et al (2012). Time course of Graves' ophthalmopathy after total thyroidectomy alone or followed by radioiodine therapy: a 2-year longitudinal study. Endocrine, 41(2), 320-326. [More Information]
  • Girgis, C., Champion, B., Wall, J. (2011). Current concepts in Graves' disease. Therapeutic Advances in Endocrinology and Metabolism, 2(3), 135-144. [More Information]
  • Kambo, J., Girgis, C., Champion, B., Wall, J. (2011). Delayed-Onset Hypoparathyroidism in an Adolescent with Chromosome 22Q11 Deletion Syndrome. Endocrine Practice, 17(5), e123-e125. [More Information]
  • Wall, J., Lahooti, H. (2011). Pathogenesis of thyroid eye disease - does autoimmunity against the TSH receptor explain all cases? Endokrynologia Polska, 62(SUPPL. 1), 1-7. [More Information]
  • El-Kaissi, S., Bowden, J., Henry, M., Yeo, M., Champion, B., Brotchie, P., Nicholson, G., Wall, J. (2010). Association between radioiodine therapy for Graves' hyperthyroidism and thyroid-associated ophthalmopathy. International Ophthalmology Clinics, 30(4), 397-405. [More Information]
  • de Haan, S., Lahooti, H., Morris, O., Wall, J. (2010). Epitopes, immunoglobulin classes and immunoglobulin G subclasses of calsequestrin antibodies in patients with thyroid eye disease. Autoimmunity, 43(8), 698-703. [More Information]
  • Tjiang, H., Lahooti, H., McCorquodale, T., Parmar, K., Wall, J. (2010). Eye and Eyelid Abnormalities Are Common in Patients with Hashimoto's Thyroiditis. Thyroid, 20(3), 287-290. [More Information]
  • Gopinath, B., Wang, J., Kifley, A., Wall, J., Eastman, C., Leeder, S., Mitchell, P. (2010). Five-year incidence and progression of thyroid dysfunction in an older population. Internal Medicine Journal, 40(9), 642-649. [More Information]
  • Wall, J., Lahooti, H. (2010). Pathogenesis of thyroid eye disease - does autoimmunity against the TSH receptor explain all cases? Endokrynologia Polska, 61(2), 222-227. [More Information]
  • Lahooti, H., Parmar, K., Wall, J. (2010). Pathogenesis of thyroid-associated ophthalmopathy: does autoimmunity against calsequestrin and collagen XIII play a role? Clinical Ophthalmology, 4, 417-425. [More Information]
  • Nanan, R., Wall, J. (2010). Remission of Hashimoto's Thyroiditis in a Twelve-Year-Old Girl with Thyroid Changes Documented by Ultrasonography. Thyroid, 20(10), 1187-1190. [More Information]
  • Wall, J., Vannucchi, G., Campi, I., Bonomi, M., Covelli, D., Dazzi, D., Curro, N., Simonetta, S., Bonara, P., Persani, L., et al (2010). Rituximab treatment in patients with active Graves' orbitopathy: effects on proinflammatory and humoral immune reactions. Clinical and Experimental Immunology, 161(436), 443. [More Information]
  • Wescombe, L., Lahooti, H., Gopinath, B., Wall, J. (2010). The cardiac calsequestrin gene (CASQ2) is up-regulated in the thyroid in patients with Graves' ophthalmopathy- support for a role of autoimmunity against calsequestrin as the triggering event. Clinical Endocrinology, 73(4), 522-528. [More Information]
  • Gopinath, B., Wescombe, L., Nguyen, B., Wall, J. (2009). Can autoimmunity against calsequestrin explain the eye and eyelid muscle inflammation of thyroid eye disease? Orbit: the international journal on orbital disorders, oculoplastic and lacrimal surgery, 28(4), 256-261. [More Information]
  • Gopinath, B., Ma, G., Lahooti, H., Wall, J. (2008). A case of Hashimoto's thyroiditis presenting with chronic upper eyelid retraction and positive calsequestrin and collagen XIII antibodies. International Journal of Endocrinology and Metabolism, 6(1), 34-37.
  • Champion, B., Gopinath, B., Ma, G., El-Kaissi, S., Wall, J. (2008). Conversion to Graves' hyperthyroidism in a patient with hypothyroidism due to Hashimoto's thyroiditis documented by real-time thyroid ultrasonography. Thyroid, 18(10), 1135-1137. [More Information]
  • Nguyen, B., Gopinath, B., Tani, J., Wescombe, L., Wall, J. (2008). Peripheral blood T lymphocyte sensitisation against calsequestrin and flavoprotein in patients with Graves' ophthalmopathy. Autoimmunity, 41(5), 372-376. [More Information]
  • Gopinath, B., Wang, J., Kifley, A., Wall, J., Leeder, S., Mitchell, P. (2008). Type 2 diabetes does not predict incident thyroid dysfunction in the elderly. Diabetes Research and Clinical Practice, 82(3), e11-e13. [More Information]
  • Gopinath, B., Adams, C., Musselman, R., Tani, J., Wall, J. (2007). Antibodies against calsequestrin and type XIII collagen are good markers for chronic upper eyelid retraction. Ocular Immunology and Inflammation, 15(2), 81-88. [More Information]
  • Tani, J., Gopinath, B., Nguyen, B., Wall, J. (2007). Extraocular muscle autoimmunity and orbital fat inflammation in thyroid-associated ophthalmopathy. Expert Review of Clinical Immunology, 3(3), 299-311.
  • Gopinath, B., Ma, G., Wall, J. (2007). Eye Signs and Serum Eye Muscle and Collagen XIII Antibodies in Patients with Transient and Progressive Thyroiditis. Thyroid, 17(11), 1123-1129. [More Information]
  • Bednarczuk, T., Gopinath, B., Ploski, R., Wall, J. (2007). Susceptibility genes in Graves' ophthalmopathy: searching for a needle in a haystack? Clinical Endocrinology, 67(1), 3-19. [More Information]
  • Watters, D., Wall, J. (2007). Thyroid surgery in the tropics. ANZ Journal of Surgery, 77(11), 933-940.
  • Gopinath, B., Musselman, R., Beard, N., El-Kaissi, S., Tani, J., Adams, C., Wall, J. (2006). Antibodies targeting the calcium binding skeletal muscle protein calsequestrin are specific markers of ophthalmopathy and sensitive indicators of ocular myopathy in patients with Graves' disease. Clinical and Experimental Immunology, 145(1), 56-62. [More Information]
  • Tani, J., Wall, J. (2006). Autoimmunity against eye-muscle antigens may explain thyroid-associated ophthalmopathy. CMAJ - Canadian Medical Association Journal, 175(3), 239. [More Information]
  • Wall, J., Stachura, I., Kennerdell, J. (2006). Mitochondrial abnormalities in eye muscle fiber from three cases of thyroid-associated ophthalmopathy. Thyroid, 16(11), 1181-3. [More Information]
  • Gopinath, B., Musselman, R., Adams, C., Tani, J., Beard, N., Wall, J. (2006). Study of Serum Antibodies Against Three Eye Muscle Antigens and the Connective Tissue Antigen Collagen XIII in Patients with Graves' Disease With and Without Ophthalmopathy: Correlation With Clinical Features. Thyroid, 16(10), 967-974. [More Information]
  • Hiromatsu, Y., Fukazawa, H., How, J., Tani, J., Wall, J. (2005). Serum Containing Inhibitory Factors Which Inhibit Natural Cytotoxicity in Patients With Differentiated Thyroid Cancer. International Journal of Endocrinology and Metabolism, 1, 25-32.
  • Kloprogge, S., Kowal, L., Wall, J., Frauman, A. (2005). The clinicopathologic basis of Graves' ophthalmopathy: a review. European Journal of Ophthalmology, 15(3), 315-323. [More Information]
  • Mizokami, T., Li, A., El-Kaissi, S., Wall, J. (2004). Stress And Thyroid Autoimmunity. Thyroid, 14(12), 1047-1055.

2013

  • Gopinath, B., Harris, D., Wall, J., Kifley, A., Mitchell, P. (2013). Relationship between thyroid dysfunction and chronic kidney disease in community-dwelling older adults. Maturitas, 75(2), 159-164. [More Information]

2012

  • Nguyen, B., Gopinath, B., Ma, G., Champion, B., Wall, J. (2012). Cell mediated Immunity Against Three Eye Muscle Antigens and Correlation with Eye Signs in Patients with Transient and Chronic Thyroiditis. The Open Autoimmunity Journal, 4, 4-9.
  • Ardley, M., McCorquodale, T., Lahooti, H., Champion, B., Wall, J. (2012). Eye findings and immunological markers in probands and their euthyroid relatives from a single family with multiple cases of thyroid autoimmunity. Thyroid Research, 5(1), 1-6. [More Information]
  • McCorquodale, T., Lahooti, H., Gopinath, B., Wall, J. (2012). Long-term follow-up of seven patients with ophthalmopathy not associated with thyroid autoimmunity: heterogeneity of autoimmune ophthalmopathy. Clinical Ophthalmology, 6, 1063-1071. [More Information]
  • El-Kaissi, S., Wall, J. (2012). Targeting the thyrotropin receptor in thyroid disease. Expert Opinion on Therapeutic Targets, 16(7), 719-727. [More Information]
  • Wall, J., Champion, B. (2012). The Role of Real-Time Thyroid Ultrasonography in the Assessment and Management of Patients with Hashimoto's Thyroiditis. In Drahomira Springer (Eds.), Hypothyroidism – Influences and Treatments, (pp. 167-180). Croatia: InTech Publishers.
  • De Bellis, A., Conzo, G., Cennamo, G., Pane, E., Bellastella, G., Colella, C., Dello Iacovo, A., Paglionico, V., Sinisi, A., Wall, J., et al (2012). Time course of Graves' ophthalmopathy after total thyroidectomy alone or followed by radioiodine therapy: a 2-year longitudinal study. Endocrine, 41(2), 320-326. [More Information]

2011

  • Girgis, C., Champion, B., Wall, J. (2011). Current concepts in Graves' disease. Therapeutic Advances in Endocrinology and Metabolism, 2(3), 135-144. [More Information]
  • Kambo, J., Girgis, C., Champion, B., Wall, J. (2011). Delayed-Onset Hypoparathyroidism in an Adolescent with Chromosome 22Q11 Deletion Syndrome. Endocrine Practice, 17(5), e123-e125. [More Information]
  • Wall, J., Lahooti, H. (2011). Pathogenesis of thyroid eye disease - does autoimmunity against the TSH receptor explain all cases? Endokrynologia Polska, 62(SUPPL. 1), 1-7. [More Information]

2010

  • El-Kaissi, S., Bowden, J., Henry, M., Yeo, M., Champion, B., Brotchie, P., Nicholson, G., Wall, J. (2010). Association between radioiodine therapy for Graves' hyperthyroidism and thyroid-associated ophthalmopathy. International Ophthalmology Clinics, 30(4), 397-405. [More Information]
  • de Haan, S., Lahooti, H., Morris, O., Wall, J. (2010). Epitopes, immunoglobulin classes and immunoglobulin G subclasses of calsequestrin antibodies in patients with thyroid eye disease. Autoimmunity, 43(8), 698-703. [More Information]
  • Tjiang, H., Lahooti, H., McCorquodale, T., Parmar, K., Wall, J. (2010). Eye and Eyelid Abnormalities Are Common in Patients with Hashimoto's Thyroiditis. Thyroid, 20(3), 287-290. [More Information]
  • Gopinath, B., Wang, J., Kifley, A., Wall, J., Eastman, C., Leeder, S., Mitchell, P. (2010). Five-year incidence and progression of thyroid dysfunction in an older population. Internal Medicine Journal, 40(9), 642-649. [More Information]
  • Wall, J., Lahooti, H. (2010). Pathogenesis of thyroid eye disease - does autoimmunity against the TSH receptor explain all cases? Endokrynologia Polska, 61(2), 222-227. [More Information]
  • Lahooti, H., Parmar, K., Wall, J. (2010). Pathogenesis of thyroid-associated ophthalmopathy: does autoimmunity against calsequestrin and collagen XIII play a role? Clinical Ophthalmology, 4, 417-425. [More Information]
  • Nanan, R., Wall, J. (2010). Remission of Hashimoto's Thyroiditis in a Twelve-Year-Old Girl with Thyroid Changes Documented by Ultrasonography. Thyroid, 20(10), 1187-1190. [More Information]
  • Wall, J., Vannucchi, G., Campi, I., Bonomi, M., Covelli, D., Dazzi, D., Curro, N., Simonetta, S., Bonara, P., Persani, L., et al (2010). Rituximab treatment in patients with active Graves' orbitopathy: effects on proinflammatory and humoral immune reactions. Clinical and Experimental Immunology, 161(436), 443. [More Information]
  • Wescombe, L., Lahooti, H., Gopinath, B., Wall, J. (2010). The cardiac calsequestrin gene (CASQ2) is up-regulated in the thyroid in patients with Graves' ophthalmopathy- support for a role of autoimmunity against calsequestrin as the triggering event. Clinical Endocrinology, 73(4), 522-528. [More Information]

2009

  • Gopinath, B., Wescombe, L., Nguyen, B., Wall, J. (2009). Can autoimmunity against calsequestrin explain the eye and eyelid muscle inflammation of thyroid eye disease? Orbit: the international journal on orbital disorders, oculoplastic and lacrimal surgery, 28(4), 256-261. [More Information]

2008

  • Gopinath, B., Ma, G., Lahooti, H., Wall, J. (2008). A case of Hashimoto's thyroiditis presenting with chronic upper eyelid retraction and positive calsequestrin and collagen XIII antibodies. International Journal of Endocrinology and Metabolism, 6(1), 34-37.
  • Champion, B., Gopinath, B., Ma, G., El-Kaissi, S., Wall, J. (2008). Conversion to Graves' hyperthyroidism in a patient with hypothyroidism due to Hashimoto's thyroiditis documented by real-time thyroid ultrasonography. Thyroid, 18(10), 1135-1137. [More Information]
  • Nguyen, B., Gopinath, B., Tani, J., Wescombe, L., Wall, J. (2008). Peripheral blood T lymphocyte sensitisation against calsequestrin and flavoprotein in patients with Graves' ophthalmopathy. Autoimmunity, 41(5), 372-376. [More Information]
  • Gopinath, B., Wang, J., Kifley, A., Wall, J., Leeder, S., Mitchell, P. (2008). Type 2 diabetes does not predict incident thyroid dysfunction in the elderly. Diabetes Research and Clinical Practice, 82(3), e11-e13. [More Information]

2007

  • Gopinath, B., Adams, C., Musselman, R., Tani, J., Wall, J. (2007). Antibodies against calsequestrin and type XIII collagen are good markers for chronic upper eyelid retraction. Ocular Immunology and Inflammation, 15(2), 81-88. [More Information]
  • Tani, J., Gopinath, B., Nguyen, B., Wall, J. (2007). Extraocular muscle autoimmunity and orbital fat inflammation in thyroid-associated ophthalmopathy. Expert Review of Clinical Immunology, 3(3), 299-311.
  • Gopinath, B., Ma, G., Wall, J. (2007). Eye Signs and Serum Eye Muscle and Collagen XIII Antibodies in Patients with Transient and Progressive Thyroiditis. Thyroid, 17(11), 1123-1129. [More Information]
  • Bednarczuk, T., Gopinath, B., Ploski, R., Wall, J. (2007). Susceptibility genes in Graves' ophthalmopathy: searching for a needle in a haystack? Clinical Endocrinology, 67(1), 3-19. [More Information]
  • Watters, D., Wall, J. (2007). Thyroid surgery in the tropics. ANZ Journal of Surgery, 77(11), 933-940.

2006

  • Gopinath, B., Musselman, R., Beard, N., El-Kaissi, S., Tani, J., Adams, C., Wall, J. (2006). Antibodies targeting the calcium binding skeletal muscle protein calsequestrin are specific markers of ophthalmopathy and sensitive indicators of ocular myopathy in patients with Graves' disease. Clinical and Experimental Immunology, 145(1), 56-62. [More Information]
  • Tani, J., Wall, J. (2006). Autoimmunity against eye-muscle antigens may explain thyroid-associated ophthalmopathy. CMAJ - Canadian Medical Association Journal, 175(3), 239. [More Information]
  • Wall, J., Stachura, I., Kennerdell, J. (2006). Mitochondrial abnormalities in eye muscle fiber from three cases of thyroid-associated ophthalmopathy. Thyroid, 16(11), 1181-3. [More Information]
  • Gopinath, B., Musselman, R., Adams, C., Tani, J., Beard, N., Wall, J. (2006). Study of Serum Antibodies Against Three Eye Muscle Antigens and the Connective Tissue Antigen Collagen XIII in Patients with Graves' Disease With and Without Ophthalmopathy: Correlation With Clinical Features. Thyroid, 16(10), 967-974. [More Information]

2005

  • Hiromatsu, Y., Fukazawa, H., How, J., Tani, J., Wall, J. (2005). Serum Containing Inhibitory Factors Which Inhibit Natural Cytotoxicity in Patients With Differentiated Thyroid Cancer. International Journal of Endocrinology and Metabolism, 1, 25-32.
  • Kloprogge, S., Kowal, L., Wall, J., Frauman, A. (2005). The clinicopathologic basis of Graves' ophthalmopathy: a review. European Journal of Ophthalmology, 15(3), 315-323. [More Information]

2004

  • Mizokami, T., Li, A., El-Kaissi, S., Wall, J. (2004). Stress And Thyroid Autoimmunity. Thyroid, 14(12), 1047-1055.

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