Professor Jacob George
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Professor of Gastroenterology & Hepatic Medicine
C24 - Westmead Hospital |
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Research interests
Professor George undertakes basic research on non-alcoholic steatohepatitis (NASH) and hepatic fibrosis. He is also researching the molecular and cellular basis for disease progression in chronic hepatitis C. He has published seminal papers on the central role of transforming growth factor beta (TGF beta) in fibrogenesis.
Current national competitive grants*
2011
The effect of IL28B haplotype on hepatitis C virus infection and treatment response
Booth D, Ahlenstiel G, Stewart G, George J
National Health and Medical Research Council Project Grant ($507,957 over 3 years)
Role of adiponectin in hepatic carcinogenesis
George J, Hebbard L
National Health and Medical Research Council Project Grant ($361,083 over 3 years)
The role of adiponectin-mediated nitric oxide on portal hypertension and liver fibrosis
George J, Wang J
National Health and Medical Research Council Project Grant ($508,390 over 3 years)
The role of endocannabinoids in chronic hepatitis C
George J, Douglas M
National Health and Medical Research Council Project Grant ($543,390 over 3 years)
* Grants administered through the University of Sydney
PhD and Masters' project opportunities
Identification and characterization of liver cancer stem cells from chemically induced liver cancer
Characterization of ARL6IP5, PTPLB, and NIN in liver cancer
Regulatory role of interleukin 6 (IL-6) on Notch signalling and impact on liver cancer
The Role of Leptin in Modulating Alcohol-Associated Hepatic fibrosis: An in vitro study