Dr James Chong

PhD, FRACP, MBBS,
Senior Lecturer
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 6795
Fax +61 2 9845 8323

Curriculum vitae Curriculum vitae

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Biographical details

Dr James Chong is a Cardiologist at Westmead Hospital and Senior Lecturer at the University of Sydney. His clinical interests focus on coronary intervention whilst his research focuses on the potential use of stem cells to regenerate damaged myocardium. Hisdoctoral training was performed on a previously unidentified population of cardiac stem cells in the adult murine heart. This training at the Victor Chang Cardiac Research Institute focused on using genetic-mouse models to dissect the lineage origins of this stem cell population. Post-doctoral training at the University of Washington (Seattle, USA) investigated the ability of cardiomyocytes derived from embryonic/induced-pluripotent stem cells to repair the infarcted heart.

Current projects

Human Cardiac Stem Cells for Cardiac Regeneration and Repair

Awards and honours

2014 Ministerial Award for Rising Stars in Cardiovascular Research (NSW Govt/Heart Foundation)

2014 Sydney Medical Foundation Chapman Fellowship

2013 Ludwig Engel Fellowship, Westmead Millennium Institute/Westmead Hospital.

2011 National Health and Medical Research Council Overseas Biomedical Training (CJ Martin) Fellowship.

2011 Australian-American Fulbright Commision Scholarship.

2009 Ralph Reader Prize (Basic Science) Finalist - Cardiac Society of Australia and New Zealand Annual Scientific Meeting 2009. Young Investigator Award.

2009 Cardiac Society of Australia and New Zealand Travelling Fellowship to American Heart Association Scientific Sessions.

2009 Network in Genes and Environment in Development, Travel Grant Award.

2009 University of New South Wales Post Graduate Support Scheme Grant.2008 National Heart Foundation Postgraduate Research Scholarship.

2007 Australian Stem Cell Centre Student Bursary.

2007 Australian Postgraduate Award (Australian Government).

2007 Mc Caughey Trust Research Scholarship Royal Australasian College of Physicians

2007 Pfizer Cardiovascular Travel Grant 2007.

In the media

Keywords

Cardiovascular diseases; Atherosclerosis; Stem cells

Clinical Specialty

Cardiology

International links

United States

(University of Washington) Close collaborative relationship with Prof Charles (Chuck) Murry, Director of the Institute for Stem Cells and Regenerative Medicine.

Selected grants

2015

  • Clinical Translation of Human Pluripotent Stem Cell Derived Cardiomyocytes; Chong J; National Heart Foundation/Future Leader Fellowship.
  • Clinical Translation of Human Pluripotent Stem Cells for Heart Failure (Catalyst funding for University of Washington Collaboration).; Chong J, Kizana E, Murry C; DVC International/IPDF Grant.
  • Activation and Rejuvenation of Endogenous Cardiac Stem Cells; Chong J; Heart Foundation of Australia/NSW Cardiovascular Research Network (CVRN) Research Development Project Grant.
  • International Program Development Fund – 2015 Round; Chong J; University of Sydney/International Program Development Fund.
  • Human cardiomyocyte and mesenchymal stem cell production for animal models of cardiac disease; Chong J; Agency for Science, Technology and Research/Bioprocessing Technology Institute, Biomedical Sciences Institutes.

2014

  • Human Cardiac Stem Cells for Heart Regeneration; Chong J; Royal Australasian College of Physicians/Vincent Fairfax Family Foundation Research Establishment Fellowship.
  • Sydney Medical School New Staff/Early Career Researcher Scheme 2014; Chong J; University of Sydney/Early Career Researcher.

2013

  • Improving Survival and Function of Stem Cell Derived Human Heart Muscle Grafts; Chong J; National Health and Medical Research Council (NHMRC)/Early Career Fellowships (ECF).
  • Ludwig Engel Memorial Fellowship; Chong J, Chong J; Westmead Millenium Institute/Ludwig Engel Memorial Fellowship.

Selected publications

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Journals

  • Chong, J., Murry, C. (2014). Cardiac regeneration using pluripotent stem cells-Progression to large animal models. Stem Cell Research, 13(3), 654-665. [More Information]
  • Chong, J., Forte, E., Harvey, R. (2014). Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells. Stem Cell Research, 13(3), 592-614. [More Information]
  • Al Raisi, S., Pouliopoulos, J., Barry, M., Swinnen, J., Thiagalingam, A., Thomas, S., Sivagangabalan, G., Chow, C., Chong, J., Kizana, E., Kovoor, P. (2014). Evaluation of lesion and thermodynamic characteristics of Symplicity and EnligHTN renal denervation systems in a phantom renal artery model. EuroIntervention, 10(2), 277-284. [More Information]
  • Chong, J., Yang, X., Don, C., Minami, E., Liu, Y., Weyers, J., Mahoney, W., Van Biber, B., Cook, S., et al (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510(7504), 273-277. [More Information]
  • Murry, C., Chong, J., Laflamme, M. (2014). Letter by Murry et al Regarding Article, “Embryonic Stem Cell–Derived Cardiac Myocytes Are Not Ready for Human Trials�? Circulation Research, 115(10), e28-e29. [More Information]
  • Matar, A., Chong, J. (2014). Stem cell therapy for cardiac dysfunction. SpringerPlus, 3(1), 1-14. [More Information]
  • Chong, J., Chong, B. (2013). HIT: nucleic acid masquerading as heparin. Blood, 122(2), 156-158. [More Information]
  • Chong, J., Reinecke, H., Iwata, M., Torok-Storb, B., Stempien-Otero, A., Murry, C. (2013). Progenitor Cells Identi�?ed by PDGFR-Alpha Expression in the Developing and Diseased Human Heart. Stem Cells and Development, 22(13), 1932-1943. [More Information]
  • Chong, J. (2012). Cell therapy for left ventricular dysfunction: an overview for cardiac clinicians. Heart, Lung and Circulation, 21(9), 532-542. [More Information]
  • Chong, J., Chandrakanthan, V., Xaymardan, M., Asli, N., Li, J., Ahmed, I., Heffernan, C., Menon, M., Scarlett, C., Rashidianfar, A., Zoellner, H., et al (2011). Adult Cardiac-Resident MSC-like Stem Cells with a Proepicardial Origin. Cell Stem Cell, 9(6), 527-540. [More Information]
  • Chong, B., Chong, J. (2010). IVIg immune inhibitory activity: APC is key. Blood, 115(9), 1663-1164. [More Information]
  • Chong, J., Ganesan, A., Eipper, V., Kovoor, P. (2008). Comparison of left ventricular ejection fraction and inducible ventricular tachycardia in ST-elevation myocardial infarction treated by primary angioplasty versus thrombolysis. The American Journal of Cardiology, 101(2), 153-157. [More Information]
  • Chong, J., Chard, R., McKay, T., Thomas, L. (2008). Two-dimensional and three-dimensional transthoracic echocardiography in surgical planning for right atrial metastatic melanoma. European Journal of Echocardiography, 9. [More Information]

2014

  • Chong, J., Murry, C. (2014). Cardiac regeneration using pluripotent stem cells-Progression to large animal models. Stem Cell Research, 13(3), 654-665. [More Information]
  • Chong, J., Forte, E., Harvey, R. (2014). Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells. Stem Cell Research, 13(3), 592-614. [More Information]
  • Al Raisi, S., Pouliopoulos, J., Barry, M., Swinnen, J., Thiagalingam, A., Thomas, S., Sivagangabalan, G., Chow, C., Chong, J., Kizana, E., Kovoor, P. (2014). Evaluation of lesion and thermodynamic characteristics of Symplicity and EnligHTN renal denervation systems in a phantom renal artery model. EuroIntervention, 10(2), 277-284. [More Information]
  • Chong, J., Yang, X., Don, C., Minami, E., Liu, Y., Weyers, J., Mahoney, W., Van Biber, B., Cook, S., et al (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature, 510(7504), 273-277. [More Information]
  • Murry, C., Chong, J., Laflamme, M. (2014). Letter by Murry et al Regarding Article, “Embryonic Stem Cell–Derived Cardiac Myocytes Are Not Ready for Human Trials�? Circulation Research, 115(10), e28-e29. [More Information]
  • Matar, A., Chong, J. (2014). Stem cell therapy for cardiac dysfunction. SpringerPlus, 3(1), 1-14. [More Information]

2013

  • Chong, J., Chong, B. (2013). HIT: nucleic acid masquerading as heparin. Blood, 122(2), 156-158. [More Information]
  • Chong, J., Reinecke, H., Iwata, M., Torok-Storb, B., Stempien-Otero, A., Murry, C. (2013). Progenitor Cells Identi�?ed by PDGFR-Alpha Expression in the Developing and Diseased Human Heart. Stem Cells and Development, 22(13), 1932-1943. [More Information]

2012

  • Chong, J. (2012). Cell therapy for left ventricular dysfunction: an overview for cardiac clinicians. Heart, Lung and Circulation, 21(9), 532-542. [More Information]

2011

  • Chong, J., Chandrakanthan, V., Xaymardan, M., Asli, N., Li, J., Ahmed, I., Heffernan, C., Menon, M., Scarlett, C., Rashidianfar, A., Zoellner, H., et al (2011). Adult Cardiac-Resident MSC-like Stem Cells with a Proepicardial Origin. Cell Stem Cell, 9(6), 527-540. [More Information]

2010

  • Chong, B., Chong, J. (2010). IVIg immune inhibitory activity: APC is key. Blood, 115(9), 1663-1164. [More Information]

2008

  • Chong, J., Ganesan, A., Eipper, V., Kovoor, P. (2008). Comparison of left ventricular ejection fraction and inducible ventricular tachycardia in ST-elevation myocardial infarction treated by primary angioplasty versus thrombolysis. The American Journal of Cardiology, 101(2), 153-157. [More Information]
  • Chong, J., Chard, R., McKay, T., Thomas, L. (2008). Two-dimensional and three-dimensional transthoracic echocardiography in surgical planning for right atrial metastatic melanoma. European Journal of Echocardiography, 9. [More Information]

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