Dr James (Tim) Howells

Bill Gole MND Research Fellow
Sydney Medical School


Map

Current research students

Project title Research student
Chemotherapy-specific neuropathy profiles, risk factors and assessment tools in chemotherapy-induced peripheral neuropathy Hannah TIMMINS

Selected grants

2018

  • Hyperexcitability of motor neurons in Motor Neurone Disease; Howells J; Brain Foundation of Australia/Dawn Wallace Fellowship.

2015

  • Hyperexcitability of the lower motor neuron in ALS; Howells J; Motor Neurone Disease Research Institute of Australia/Postdoctoral Fellowship.

Selected publications

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Book Chapters

  • Burke, D., Howells, J. (2017). The motor unit. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 9-17). Oxford: Oxford University Press. [More Information]

Journals

  • Garg, N., Park, S., Howells, J., Noto, Y., Vucic, S., Yiannikas, C., Tomlinson, S., Huynh, W., Simon, N., Mathey, E., Spies, J., Pollard, J., Kiernan, M., et al (2018). Anti-MAG neuropathy: Role of IgM antibodies, the paranodal junction and juxtaparanodal potassium channels. Clinical Neurophysiology, 129(10), 2162-2169. [More Information]
  • Matamala, J., Howells, J., Dharmadasa, T., Huynh, W., Park, S., Burke, D., Kiernan, M. (2018). Excitability of sensory axons in amyotrophic lateral sclerosis. Clinical Neurophysiology, 129(7), 1472-1478. [More Information]
  • Tomlinson, S., Howells, J., Burke, D. (2018). In vivo assessment of neurological channelopathies: Application of peripheral nerve excitability studies. Neuropharmacology, 132, 98-107. [More Information]
  • Matamala, J., Howells, J., Dharmadasa, T., Trinh, T., Ma, Y., Lera, L., Vucic, S., Burke, D., Kiernan, M. (2018). Inter-session reliability of short-interval intracortical inhibition measured by threshold tracking TMS. Neuroscience Letters, 674, 18-23. [More Information]
  • Garg, N., Park, S., Yiannikas, K., Vucic, S., Howells, J., Noto, Y., Mathey, E., Pollard, J., Kiernan, M. (2018). Neurofascin-155 IgG4 Neuropathy: Pathophysiological insights, spectrum of clinical severity and response to treatment. Muscle and Nerve, 57(5), 848-851. [More Information]
  • van den Bos, M., Menon, P., Howells, J., Geevasinga, N., Kiernan, M., Vucic, S. (2018). Physiological Processes Underlying Short Interval Intracortical Facilitation in the Human Motor Cortex. Frontiers in Neuroscience, 12, 240. [More Information]
  • Agarwal, S., Highton-Williamson, E., Caga, J., Matamala, J., Dharmadasa, T., Howells, J., Zoing, M., Shibuya, K., Geevasinga, N., Vucic, S., Hodges, J., Ahmed, R., Kiernan, M. (2018). Primary lateral sclerosis and the amyotrophic lateral sclerosis-frontotemporal dementia spectrum. Journal of Neurology, 265(8), 1819-1828. [More Information]
  • Boland-Freitas, R., Lee, J., Howells, J., Liang, C., Corbett, A., Nicholson, G., Ng, K. (2018). Sarcolemmal excitability in the myotonic dystrophies. Muscle and Nerve, 57(4), 595-602. [More Information]
  • Howells, J., Bostock, H., Park, S., Kiernan, M., Burke, D. (2018). Tracking small sensory nerve action potentials in human axonal excitability studies. Journal of Neuroscience Methods, 298, 45-53. [More Information]
  • Farrar, M., Lee, M., Howells, J., Andrews, P., Lin, C. (2017). Burning pain: axonal dysfunction in erythromelalgia. Pain, 158(5), 900-911. [More Information]
  • Matamala, J., Geevasinga, N., Huynh, W., Dharmadasa, T., Howells, J., Simon, N., Menon, P., Vucic, S., Kiernan, M. (2017). Cortical function and corticomotoneuronal adaptation in monomelic amyotrophy. Clinical Neurophysiology, 128(8), 1488-1495. [More Information]
  • Garg, N., Park, S., Vucic, S., Yiannikas, C., Spies, J., Howells, J., Huynh, W., Matamala, J., Krishnan, A., Pollard, J., Kiernan, M., et al (2017). Differentiating lower motor neuron syndromes. Journal of Neurology, Neurosurgery and Psychiatry, 88(6), 474-483. [More Information]
  • Kanagaratnam, M., Pendleton, C., Souza, D., Pettit, J., Howells, J., Baker, M. (2017). Diuretic-sensitive electroneutral Na(+) movement and temperature effects on central axons. Journal of Physiology, 595(11), 3471-3482. [More Information]
  • Shibuya, K., Park, S., Howells, J., Huynh, W., Noto, Y., Shahrizaila, N., Matamala, J., Vucic, S., Kiernan, M. (2017). Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking. Muscle and Nerve, 55(3), 424-427. [More Information]
  • Garg, N., Howells, J., Yiannikas, C., Vucic, S., Krishnan, A., Spies, J., Bostock, H., Mathey, E., Pollard, J., Park, S., Kiernan, M. (2017). Motor unit remodelling in multifocal motor neuropathy: The importance of axonal loss. Clinical Neurophysiology, 128(10), 2022-2028. [More Information]
  • Simon, N., Lagopoulos, J., Paling, S., Pfluger, C., Park, S., Howells, J., Gallagher, T., Kliot, M., Henderson, R., Vucic, S., Kiernan, M. (2017). Peripheral nerve diffusion tensor imaging as a measure of disease progression in ALS. Journal of Neurology, 264(5), 882-890. [More Information]
  • Burke, D., Howells, J., Kiernan, M. (2017). Sensory and motor axons are different: implications for neurological disease. Annals of Clinical Neurophysiology, 19(1), 3-12. [More Information]
  • Shibuya, K., Simon, N., Geevasinga, N., Menon, P., Howells, J., Park, S., Huynh, W., Noto, Y., Vucic, S., Kiernan, M. (2017). The evolution of motor cortical dysfunction in amyotrophic lateral sclerosis. Clinical Neurophysiology, 128, 1075-1082. [More Information]
  • Howells, J., Bostock, H., Burke, D. (2016). Accommodation to hyperpolarization of human axons assessed in the frequency domain. Journal of Neurophysiology, 116(2), 322-335. [More Information]
  • Huynh, W., Pickering, H., Howells, J., Murray, J., Cormack, C., Lin, C., Vucic, S., Kiernan, M., Krishnan, A. (2016). Effect of fampridine on axonal excitability in multiple sclerosis. Clinical Neurophysiology, 127(7), 2636-2642. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Howells, J., Kiernan, M., Lin, C., Krishnan, A. (2016). In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes. Clinical Neurophysiology, 127(2), 1700-1706. [More Information]
  • Shibuya, K., Park, S., Geevasinga, N., Menon, P., Howells, J., Simon, N., Huynh, W., Noto, Y., Gotz, J., Kril, J., Vucic, S., Kiernan, M., et al (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87(5), 513-520. [More Information]
  • Shibuya, K., Park, S., Geevasinga, N., Huynh, W., Simon, N., Menon, P., Howells, J., Vucic, S., Kiernan, M. (2016). Threshold tracking transcranial magnetic stimulation: Effects of age and gender on motor cortical function. Clinical Neurophysiology, 127(6), 2355-2361. [More Information]
  • Geevasinga, N., Menon, P., Howells, J., Nicholson, G., Kiernan, M., Vucic, S. (2015). Axonal Ion Channel Dysfunction in C9orf72 Familial Amyotrophic Lateral Sclerosis. JAMA Neurology, 72(1), 49-57. [More Information]
  • Geevasinga, N., Menon, P., Nicholson, G., Ng, K., Howells, J., Kril, J., Yannikas, C., Kiernan, M., Vucic, S. (2015). Cortical Function in Asymptomatic Carriers and Patients With C9orf72 Amyotrophic Lateral Sclerosis. JAMA Neurology, 72(11), 1268-1274. [More Information]
  • Czesnik, D., Howells, J., Negro, F., Wagenknecht, M., Hanner, S., Farina, D., Burke, D., Paulus, W. (2015). Increased HCN channel driven inward rectification in benign cramp fasciculation syndrome. Brain, 138(11), 3168-3179. [More Information]
  • Simon, N., Lin, C., Lee, M., Howells, J., Vucic, S., Burke, D., Kiernan, M. (2015). Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis. Clinical Neurophysiology, 126(4), 828-836. [More Information]
  • Menon, P., Geevasinga, N., Yiannikas, K., Howells, J., Kiernan, M., Vucic, S. (2015). Sensitivity and specificity of threshold tracking transcranial magnetic stimulation for diagnosis of amyotrophic lateral sclerosis: A prospective study. The Lancet Neurology, 14(5), 478-484. [More Information]
  • Liang, C., Howells, J., Kennerson, M., Nicholson, G., Burke, D., Ng, K. (2014). Axonal excitability in X-linked dominant Charcot Marie Tooth disease. Clinical Neurophysiology, 125(6), 1261-1269. [More Information]
  • Arnold, R., Pussell, B., Howells, J., Grinius, V., Kiernan, M., Lin, C., Krishnan, A. (2014). Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease. Clinical Neurophysiology, 125(1), 179-185. [More Information]
  • Ng, K., Howells, J., Pollard, J., Burke, D. (2013). Different mechanisms underlying changes in excitability of peripheral nerve sensory and motor axons in multiple sclerosis. Muscle and Nerve, 47(1), 53-60. [More Information]
  • Arnold, R., Pussell, B., Pianta, T., Grinius, V., Lin, C., Kiernan, M., Howells, J., Jardine, M., Krishnan, A. (2013). Effects of hemodiafiltration and high flux hemodialysis on nerve excitability in end-stage kidney disease. PloS One, 8(3), 1-8. [More Information]
  • Howells, J., Czesnik, D., Trevillion, L., Burke, D. (2013). Excitability and the safety margin in human axons during hyperthermia. Journal of Physiology, 591(12), 3063-3080. [More Information]
  • Burke, D., Howells, J., Tomlinson, S. (2013). HCN Channels: Function and clinical implications. Neurology, 81(5), 513-514. [More Information]
  • Menezes, M., Waddell, L., Evesson, F., Cooper, S., Webster, R., Jones, K., Mowat, D., Kiernan, M., Johnston, H., Corbett, A., North, K., Clarke, N., et al (2012). Importance and challenge of making an early diagnosis in LMNA-related muscular dystrophy. Neurology, 78(16), 1258-1263. [More Information]
  • Howells, J., Trevillion, L., Bostock, H., Burke, D. (2012). The voltage dependence of Ih in human myelinated axons. Journal of Physiology, 590(7), 1625-1640. [More Information]
  • Trevillion, L., Howells, J., Tomlinson, S., Bostock, H., Burke, D. (2011). What makes some axons more excitable than others. Physiology News, 82, 32-35.
  • Trevillion, L., Howells, J., Bostock, H., Burke, D. (2010). Properties of Low-Threshold Motor Axons in the Human Median Nerve. Journal of Physiology, 288(13), 2503-2515. [More Information]
  • Burke, D., Howells, J., Trevillion, L., McNulty, P., Jankelowitz, S., Kiernan, M. (2009). Threshold behaviour of human axons explored using subthreshold perturbations to membrane potential. Journal of Physiology, 587(2), 491-504. [More Information]
  • Lo, H., Cooper, S., Evesson, F., Seto, J., Chiotis, M., Tay, V., Compton, A., Cairns, A., Corbett, A., MacArthur, D., North, K., et al (2008). Limb-girdle muscular dystrophy: Diagnostic evaluation, frequency and clues to pathogenesis. Neuromuscular Disorders, 18(1), 34-44. [More Information]
  • Ng, K., Howells, J., Pollard, J., Burke, D. (2008). Up-regulation of slow K+ channels in peripheral motor axons: a transcriptional channelopathy in multiple sclerosis. Brain, 131(11), 3062-3071. [More Information]
  • Burke, D., Howells, J., Trevillion, L., Kiernan, M., Bostock, H. (2007). Inflections in threshold electrotonus to depolarizing currents in sensory axons. Muscle and Nerve, 36(6), 849-852. [More Information]
  • Trevillion, L., Howells, J., Burke, D. (2007). Outwardly rectifying deflections in threshold electrotonus due to K+ conductances. Journal of Physiology, 580(2), 685-696. [More Information]
  • Jankelowitz, S., Howells, J., Burke, D. (2007). Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects. Journal of Physiology, 581(3), 927-940. [More Information]
  • Vucic, S., Howells, J., Trevillion, L., Kiernan, M. (2006). Assessment of cortical excitability using threshold tracking techniques. Muscle and Nerve, 33(4), 477-486. [More Information]
  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). Augmentation of the contraction force of human thenar muscles by and during brief discharge trains. Muscle and Nerve, 33(3), 384-392. [More Information]
  • Bostock, H., Lin, C., Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2005). After-effects of near-threshold stimulation in single human motor axons. Journal of Physiology, 564(3), 931-940. [More Information]
  • Trevillion, L., Howells, J., Jankelowitz, S., Burke, D. (2004). Axonal Excitability Measured By Tracking Twitch Contraction Force. Muscle and Nerve, 30(4), 437-443. [More Information]

Conferences

  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). The Catch-Like property of human thenar muscles studied during brief trains of discharges. XIth International Congress on Neuromuscular Diseases, United Kingdom: Elsevier.

2018

  • Garg, N., Park, S., Howells, J., Noto, Y., Vucic, S., Yiannikas, C., Tomlinson, S., Huynh, W., Simon, N., Mathey, E., Spies, J., Pollard, J., Kiernan, M., et al (2018). Anti-MAG neuropathy: Role of IgM antibodies, the paranodal junction and juxtaparanodal potassium channels. Clinical Neurophysiology, 129(10), 2162-2169. [More Information]
  • Matamala, J., Howells, J., Dharmadasa, T., Huynh, W., Park, S., Burke, D., Kiernan, M. (2018). Excitability of sensory axons in amyotrophic lateral sclerosis. Clinical Neurophysiology, 129(7), 1472-1478. [More Information]
  • Tomlinson, S., Howells, J., Burke, D. (2018). In vivo assessment of neurological channelopathies: Application of peripheral nerve excitability studies. Neuropharmacology, 132, 98-107. [More Information]
  • Matamala, J., Howells, J., Dharmadasa, T., Trinh, T., Ma, Y., Lera, L., Vucic, S., Burke, D., Kiernan, M. (2018). Inter-session reliability of short-interval intracortical inhibition measured by threshold tracking TMS. Neuroscience Letters, 674, 18-23. [More Information]
  • Garg, N., Park, S., Yiannikas, K., Vucic, S., Howells, J., Noto, Y., Mathey, E., Pollard, J., Kiernan, M. (2018). Neurofascin-155 IgG4 Neuropathy: Pathophysiological insights, spectrum of clinical severity and response to treatment. Muscle and Nerve, 57(5), 848-851. [More Information]
  • van den Bos, M., Menon, P., Howells, J., Geevasinga, N., Kiernan, M., Vucic, S. (2018). Physiological Processes Underlying Short Interval Intracortical Facilitation in the Human Motor Cortex. Frontiers in Neuroscience, 12, 240. [More Information]
  • Agarwal, S., Highton-Williamson, E., Caga, J., Matamala, J., Dharmadasa, T., Howells, J., Zoing, M., Shibuya, K., Geevasinga, N., Vucic, S., Hodges, J., Ahmed, R., Kiernan, M. (2018). Primary lateral sclerosis and the amyotrophic lateral sclerosis-frontotemporal dementia spectrum. Journal of Neurology, 265(8), 1819-1828. [More Information]
  • Boland-Freitas, R., Lee, J., Howells, J., Liang, C., Corbett, A., Nicholson, G., Ng, K. (2018). Sarcolemmal excitability in the myotonic dystrophies. Muscle and Nerve, 57(4), 595-602. [More Information]
  • Howells, J., Bostock, H., Park, S., Kiernan, M., Burke, D. (2018). Tracking small sensory nerve action potentials in human axonal excitability studies. Journal of Neuroscience Methods, 298, 45-53. [More Information]

2017

  • Farrar, M., Lee, M., Howells, J., Andrews, P., Lin, C. (2017). Burning pain: axonal dysfunction in erythromelalgia. Pain, 158(5), 900-911. [More Information]
  • Matamala, J., Geevasinga, N., Huynh, W., Dharmadasa, T., Howells, J., Simon, N., Menon, P., Vucic, S., Kiernan, M. (2017). Cortical function and corticomotoneuronal adaptation in monomelic amyotrophy. Clinical Neurophysiology, 128(8), 1488-1495. [More Information]
  • Garg, N., Park, S., Vucic, S., Yiannikas, C., Spies, J., Howells, J., Huynh, W., Matamala, J., Krishnan, A., Pollard, J., Kiernan, M., et al (2017). Differentiating lower motor neuron syndromes. Journal of Neurology, Neurosurgery and Psychiatry, 88(6), 474-483. [More Information]
  • Kanagaratnam, M., Pendleton, C., Souza, D., Pettit, J., Howells, J., Baker, M. (2017). Diuretic-sensitive electroneutral Na(+) movement and temperature effects on central axons. Journal of Physiology, 595(11), 3471-3482. [More Information]
  • Shibuya, K., Park, S., Howells, J., Huynh, W., Noto, Y., Shahrizaila, N., Matamala, J., Vucic, S., Kiernan, M. (2017). Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking. Muscle and Nerve, 55(3), 424-427. [More Information]
  • Garg, N., Howells, J., Yiannikas, C., Vucic, S., Krishnan, A., Spies, J., Bostock, H., Mathey, E., Pollard, J., Park, S., Kiernan, M. (2017). Motor unit remodelling in multifocal motor neuropathy: The importance of axonal loss. Clinical Neurophysiology, 128(10), 2022-2028. [More Information]
  • Simon, N., Lagopoulos, J., Paling, S., Pfluger, C., Park, S., Howells, J., Gallagher, T., Kliot, M., Henderson, R., Vucic, S., Kiernan, M. (2017). Peripheral nerve diffusion tensor imaging as a measure of disease progression in ALS. Journal of Neurology, 264(5), 882-890. [More Information]
  • Burke, D., Howells, J., Kiernan, M. (2017). Sensory and motor axons are different: implications for neurological disease. Annals of Clinical Neurophysiology, 19(1), 3-12. [More Information]
  • Shibuya, K., Simon, N., Geevasinga, N., Menon, P., Howells, J., Park, S., Huynh, W., Noto, Y., Vucic, S., Kiernan, M. (2017). The evolution of motor cortical dysfunction in amyotrophic lateral sclerosis. Clinical Neurophysiology, 128, 1075-1082. [More Information]
  • Burke, D., Howells, J. (2017). The motor unit. In Kerry R. Mills (Eds.), Oxford Textbook of Clinical Neurophysiology, (pp. 9-17). Oxford: Oxford University Press. [More Information]

2016

  • Howells, J., Bostock, H., Burke, D. (2016). Accommodation to hyperpolarization of human axons assessed in the frequency domain. Journal of Neurophysiology, 116(2), 322-335. [More Information]
  • Huynh, W., Pickering, H., Howells, J., Murray, J., Cormack, C., Lin, C., Vucic, S., Kiernan, M., Krishnan, A. (2016). Effect of fampridine on axonal excitability in multiple sclerosis. Clinical Neurophysiology, 127(7), 2636-2642. [More Information]
  • Kwai, N., Arnold, R., Poynten, A., Howells, J., Kiernan, M., Lin, C., Krishnan, A. (2016). In vivo evidence of reduced nodal and paranodal conductances in type 1 diabetes. Clinical Neurophysiology, 127(2), 1700-1706. [More Information]
  • Shibuya, K., Park, S., Geevasinga, N., Menon, P., Howells, J., Simon, N., Huynh, W., Noto, Y., Gotz, J., Kril, J., Vucic, S., Kiernan, M., et al (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87(5), 513-520. [More Information]
  • Shibuya, K., Park, S., Geevasinga, N., Huynh, W., Simon, N., Menon, P., Howells, J., Vucic, S., Kiernan, M. (2016). Threshold tracking transcranial magnetic stimulation: Effects of age and gender on motor cortical function. Clinical Neurophysiology, 127(6), 2355-2361. [More Information]

2015

  • Geevasinga, N., Menon, P., Howells, J., Nicholson, G., Kiernan, M., Vucic, S. (2015). Axonal Ion Channel Dysfunction in C9orf72 Familial Amyotrophic Lateral Sclerosis. JAMA Neurology, 72(1), 49-57. [More Information]
  • Geevasinga, N., Menon, P., Nicholson, G., Ng, K., Howells, J., Kril, J., Yannikas, C., Kiernan, M., Vucic, S. (2015). Cortical Function in Asymptomatic Carriers and Patients With C9orf72 Amyotrophic Lateral Sclerosis. JAMA Neurology, 72(11), 1268-1274. [More Information]
  • Czesnik, D., Howells, J., Negro, F., Wagenknecht, M., Hanner, S., Farina, D., Burke, D., Paulus, W. (2015). Increased HCN channel driven inward rectification in benign cramp fasciculation syndrome. Brain, 138(11), 3168-3179. [More Information]
  • Simon, N., Lin, C., Lee, M., Howells, J., Vucic, S., Burke, D., Kiernan, M. (2015). Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis. Clinical Neurophysiology, 126(4), 828-836. [More Information]
  • Menon, P., Geevasinga, N., Yiannikas, K., Howells, J., Kiernan, M., Vucic, S. (2015). Sensitivity and specificity of threshold tracking transcranial magnetic stimulation for diagnosis of amyotrophic lateral sclerosis: A prospective study. The Lancet Neurology, 14(5), 478-484. [More Information]

2014

  • Liang, C., Howells, J., Kennerson, M., Nicholson, G., Burke, D., Ng, K. (2014). Axonal excitability in X-linked dominant Charcot Marie Tooth disease. Clinical Neurophysiology, 125(6), 1261-1269. [More Information]
  • Arnold, R., Pussell, B., Howells, J., Grinius, V., Kiernan, M., Lin, C., Krishnan, A. (2014). Evidence for a causal relationship between hyperkalaemia and axonal dysfunction in end-stage kidney disease. Clinical Neurophysiology, 125(1), 179-185. [More Information]

2013

  • Ng, K., Howells, J., Pollard, J., Burke, D. (2013). Different mechanisms underlying changes in excitability of peripheral nerve sensory and motor axons in multiple sclerosis. Muscle and Nerve, 47(1), 53-60. [More Information]
  • Arnold, R., Pussell, B., Pianta, T., Grinius, V., Lin, C., Kiernan, M., Howells, J., Jardine, M., Krishnan, A. (2013). Effects of hemodiafiltration and high flux hemodialysis on nerve excitability in end-stage kidney disease. PloS One, 8(3), 1-8. [More Information]
  • Howells, J., Czesnik, D., Trevillion, L., Burke, D. (2013). Excitability and the safety margin in human axons during hyperthermia. Journal of Physiology, 591(12), 3063-3080. [More Information]
  • Burke, D., Howells, J., Tomlinson, S. (2013). HCN Channels: Function and clinical implications. Neurology, 81(5), 513-514. [More Information]

2012

  • Menezes, M., Waddell, L., Evesson, F., Cooper, S., Webster, R., Jones, K., Mowat, D., Kiernan, M., Johnston, H., Corbett, A., North, K., Clarke, N., et al (2012). Importance and challenge of making an early diagnosis in LMNA-related muscular dystrophy. Neurology, 78(16), 1258-1263. [More Information]
  • Howells, J., Trevillion, L., Bostock, H., Burke, D. (2012). The voltage dependence of Ih in human myelinated axons. Journal of Physiology, 590(7), 1625-1640. [More Information]

2011

  • Trevillion, L., Howells, J., Tomlinson, S., Bostock, H., Burke, D. (2011). What makes some axons more excitable than others. Physiology News, 82, 32-35.

2010

  • Trevillion, L., Howells, J., Bostock, H., Burke, D. (2010). Properties of Low-Threshold Motor Axons in the Human Median Nerve. Journal of Physiology, 288(13), 2503-2515. [More Information]

2009

  • Burke, D., Howells, J., Trevillion, L., McNulty, P., Jankelowitz, S., Kiernan, M. (2009). Threshold behaviour of human axons explored using subthreshold perturbations to membrane potential. Journal of Physiology, 587(2), 491-504. [More Information]

2008

  • Lo, H., Cooper, S., Evesson, F., Seto, J., Chiotis, M., Tay, V., Compton, A., Cairns, A., Corbett, A., MacArthur, D., North, K., et al (2008). Limb-girdle muscular dystrophy: Diagnostic evaluation, frequency and clues to pathogenesis. Neuromuscular Disorders, 18(1), 34-44. [More Information]
  • Ng, K., Howells, J., Pollard, J., Burke, D. (2008). Up-regulation of slow K+ channels in peripheral motor axons: a transcriptional channelopathy in multiple sclerosis. Brain, 131(11), 3062-3071. [More Information]

2007

  • Burke, D., Howells, J., Trevillion, L., Kiernan, M., Bostock, H. (2007). Inflections in threshold electrotonus to depolarizing currents in sensory axons. Muscle and Nerve, 36(6), 849-852. [More Information]
  • Trevillion, L., Howells, J., Burke, D. (2007). Outwardly rectifying deflections in threshold electrotonus due to K+ conductances. Journal of Physiology, 580(2), 685-696. [More Information]
  • Jankelowitz, S., Howells, J., Burke, D. (2007). Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects. Journal of Physiology, 581(3), 927-940. [More Information]

2006

  • Vucic, S., Howells, J., Trevillion, L., Kiernan, M. (2006). Assessment of cortical excitability using threshold tracking techniques. Muscle and Nerve, 33(4), 477-486. [More Information]
  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). Augmentation of the contraction force of human thenar muscles by and during brief discharge trains. Muscle and Nerve, 33(3), 384-392. [More Information]
  • Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2006). The Catch-Like property of human thenar muscles studied during brief trains of discharges. XIth International Congress on Neuromuscular Diseases, United Kingdom: Elsevier.

2005

  • Bostock, H., Lin, C., Howells, J., Trevillion, L., Jankelowitz, S., Burke, D. (2005). After-effects of near-threshold stimulation in single human motor axons. Journal of Physiology, 564(3), 931-940. [More Information]

2004

  • Trevillion, L., Howells, J., Jankelowitz, S., Burke, D. (2004). Axonal Excitability Measured By Tracking Twitch Contraction Force. Muscle and Nerve, 30(4), 437-443. [More Information]

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