Professor James Kench

Clinical Professor
Pathology, Central Clinical School

Telephone +61 2 9515 7458
Fax +61 2 9515 8405

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Selected grants

2013

  • BioMark HD High-throughput Real Time & Digital PCR System for the Open Access, Multi-Disciplinary Sydney Cancer Research Core Facility; Richardson D, Scolyer R, Lee C, Halliday G, Murray M, Lay P, Christie M, Kench J, Damian D, Hersey P; Cancer Institute New South Wales/Equipment Grant.
  • Biobanking Stakeholder Network (BSN) Pre-Operative Consent Project; Yip S, Hawkins N, Miller D, Horvath L, Kench J, Brown S; Cancer Institute New South Wales/Community of Practice.
  • Robotic High Throughput Western Analysis for the Open Access, Multi-User Sydney Cancer Research Core Facility; Richardson D, Scolyer R, Boyer M, Halliday G, Damian D, Christopherson R, Joshua D, Kench J, Hong A, Murray M, Lee C, Kalinowski D, Naylor M, Lay P, Lyons G, Kovacevic Z, Mason R, Dixon K, Chan-Ling T, Hawkins C, Sunde M, Lovejoy D, Owens T, Rendina L, Jansson P, Dos Remedios C, Charles (nee Slaviero) K, Lane D, Witting P, Dong Q, Ammit A, Groundwater P, Assinder S, Bao B, Byrne S, Zhou F, Buckland M, Grewal T, Huq F, Lai D, Codd R, Zhang D, Fu D, de Graaf S, Huang M, Payne R, Slobedman B, Barrs V, Ho J, Williamson P, Murphy C; DVC Research/Equipment Grant.

2012

  • Personalising care in resectable pancreas cancer. GAP-T: a study of imaging and molecular biomarkers to guide treatment of patients receiving preoperative chemotherapy followed by surgery.; Barbour A, Goldstein D, Goldstein D, Kench J, Yip S, Brown C, Hicks R, Chang D; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Kench, J., Cosman, P., Merrett, N., Biankin, A. (2008). Pathology and Molecular Biology of Intraductal Papillary Mucinous Neoplasms. In Andrew M. Lowy, Steven D. Leach, Philip Philip (Eds.), Pancreatic Cancer, (pp. 53-64). US: Springer.

Journals

  • McKenzie, P., Delahunt, B., Kench, J., Sikaris, K. (2014). 5-alpha reductase inhibitors and PSA screening for prostate cancer. Pathology, 46(1), 91-92. [More Information]
  • Nagrial, A., Chang, D., Nguyen, N., Johns, A., Chantrill, L., Humphris, J., Chin, V., Samra, J., Gill, A., Pajic, M., Chou, A., Kench, J., Horvath, L., et al (2014). Adjuvant chemotherapy in elderly patients with pancreatic cancer. British Journal of Cancer, 110(2), 313-319. [More Information]
  • Yip, P., Cooper, W., Kohonen-Corish, M., Lin, B., McCaughan, B., Boyer, M., Kench, J., Horvath, L. (2014). Phosphorylated Akt expression is a prognostic marker in early-stage non-small cell lung cancer. Journal of Clinical Pathology, 67(4), 333-340. [More Information]
  • Gzell, C., Kench, J., Stockler, M., Hruby, G. (2013). Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature. International Urology and Nephrology, 45(3), 735-742. [More Information]
  • Cooper, C., O'Toole, S., Kench, J. (2013). Classification, morphology and molecular pathology of premalignant lesions of the pancreas. Pathology, 45(3), 286-304. [More Information]
  • Kench, J., Delahunt, B., Griffiths, D., Humphrey, P., McGowan, T., Trpkov, K., Varma, M., Wheeler, T., Srigley, J. (2013). Dataset for reporting of prostate carcinoma in radical prostatectomy specimens: recommendations from the International Collaboration on Cancer Reporting. Histopathology, 62(2), 203-218. [More Information]
  • Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013). EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology, 66(9), 744-748. [More Information]
  • Coker, D., Kench, J., Ansari, N., Zhou, R., Sandroussi, C. (2013). Hepatobiliary and Pancreatic: Clear cell myomelanotic tumor of ligamentum teres. Journal of Gastroenterology and Hepatology, 28(2), 381-381. [More Information]
  • Chang, D., Jamieson, N., Johns, A., Scarlett, C., Pajic, M., Chou, A., Pinese, M., Humphris, J., Jones, M., Toon, C., Samra, J., Kench, J., Gill, A., et al (2013). Histomolecular Phenotypes and Outcome in Adenocarcinoma of the Ampulla of Vater. Journal of Clinical Oncology, 31(10), 1348-1356. [More Information]
  • Hashemi, S., van der Poorten, D., Barrera Martinez, F., Bandara, P., Lux, O., Kench, J., George, J. (2013). Oxidative stress is closely associated with insulin resistance in genotypes 1 and 3 chronic hepatitis C. Hepatology International, 7(2), 516-523. [More Information]
  • Yip, P., Yu, B., Cooper, W., Selinger, C., Ng, C., Kennedy, C., Kohonen-Corish, M., McCaughan, B., Trent, R., Boyer, M., Kench, J., Horvath, L., O'Toole, S. (2013). Patterns of DNA mutations and ALK Rearrangement in Resected Node Negative Lung Adenocarcinoma. Journal of Thoracic Oncology, 8(4), 408-414. [More Information]
  • McKenzie, P., Delahunt, B., Kench, J., Ross, B., Lam, Q., DeVoss, K., Tran, H., Sikaris, K. (2013). Prostate specific antigen testing: age-related interpretation in early prostate cancer detection. Pathology, 45(4), 343-345. [More Information]
  • Young, J., Ting, K., Li, J., Moller, T., Dunn, L., Lu, Y., Moses, J., Prado-Lourenco, L., Khachigian, L., Ng, M., Lichtenstein, I., Tran, N., Shackel, N., Kench, J., McCaughan, G., Vadas, M., Gamble, J., et al (2013). Regulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood, 122(16), 2911-2919. [More Information]
  • Pang, J., Mahar, A., Shannon, K., Kench, J., Chan, C., Gupta, R. (2013). Reticular and microcystic schwannoma of the parotid gland. Pathology, 45(1), 96-98. [More Information]
  • McKenzie, P., Delahunt, B., Kench, J. (2013). The dilemmas of prostate cancer screening. Medical Journal of Australia, 199(9), 582-584. [More Information]
  • Ramponi, F., Kench, J., Simring, D., Crawford, M., Abadir, E., Harris, J. (2012). Early diagnosis and resection of an asymptomatic leiomyosarcoma of the inferior vena cava prior to caval obstruction. Journal Of Vascular Surgery, 55(2), 525-528. [More Information]
  • Graaf, E., Kench, J., Dilworth, P., Shackel, N., Strasser, S., Joseph, D., Pleass, H., Crawford, M., McCaughan, G., Verran, D. (2012). Grade of Deceased Donor Liver Macrovesicular Steatosis Impacts Graft and Recipient Outcomes More than Donor Risk Index. Journal of Gastroenterology and Hepatology, 27(3), 540-546. [More Information]
  • Savdie, R., Horvath, L., Pe Benito, R., Rasiah, K., Haynes, A., Chatfield, M., Stricker, P., Turner, J., Delprado, W., Henshall, S., Kench, J., et al (2012). High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy. BJU International, 109(12), 1794-1800. [More Information]
  • Biankin, A., Waddell, N., Kassahn, K., Gingras, M., Muthuswamy, L., Johns, A., Miller, D., Wilson, P., Patch, A., Wu, J., Gill, A., Kench, J., Pavlakis, N., Lam, V., Richardson, A., Samra, J., et al (2012). Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature, 491(7424), 399-405. [More Information]
  • Humphris, J., Chang, D., Johns, A., Scarlett, C., Pajic, M., Jones, M., Colvin, E., Nagrial, A., Chin, V., Chantrill, L., Samra, J., Gill, A., Kench, J., et al (2012). The prognostic and predictive value of serum CA19.9 in pancreatic cancer. Annals of Oncology, 23(7), 1713-1722. [More Information]
  • Nguyen, N., Johns, A., Gill, A., Ring, N., Chang, D., Clarkson, A., Merrett, N., Kench, J., Colvin, E., Scarlett, C., et al (2011). Clinical and immunohistochemical features of 34 solid pseudopapillary tumors of the pancreas. Journal of Gastroenterology and Hepatology, 26(2), 267-274. [More Information]
  • Devaney, J., Stirzaker, C., Qu, W., Song, J., Statham, A., Patterson, K., Horvath, L., Tabor, B., Coolen, M., Hulf, T., Kench, J., et al (2011). Epigenetic Deregulation Across Chromosome 2q14.2 Differentiates Normal from Prostate Cancer and Provides a Regional Panel of Novel DNA Methylation Cancer Biomarkers. Cancer Epidemiology, Biomarkers and Prevention, 20(1), 148-159. [More Information]
  • Kwong, R., Scarlett, C., Kalish, L., Cole, I., Kench, J., Sum, E., Musgrove, E., Henshall, S., Lindeman, G., Biankin, A., et al (2011). LMO4 expression in squamous cell carcinoma of the anterior tongue. Histopathology, 58(3), 477-480. [More Information]
  • Yip, P., Kench, J., Rasiah, K., Pe Benito, R., Lee, C., Stricker, P., Henshall, S., Sutherland, R., Horvath, L. (2011). Low AZGPI Expression Predicts for Recurrence in Margin-Positive, Localized Prostate Cancer. The Prostate, 71(15), 1638-1645. [More Information]
  • Scarlett, C., Salisbury, E., Biankin, A., Kench, J. (2011). Precursor lesions in pancreatic cancer: morphological and molecular pathology. Pathology, 43(3), 183-200. [More Information]
  • Kench, J., Clouston, D., Delprado, W., Eade, T., Ellis, D., Horvath, L., Samaratunga, H., Stahl, J., Stapleton, A., Egevad, L., et al (2011). Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens. Pathology, 43(5), 410-419. [More Information]
  • Scarlett, C., Colvin, E., Pinese, M., Chang, D., Morey, A., Musgrove, E., Pajic, M., Apte, M., Henshall, S., Sutherland, R., et al (2011). Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction. PLoS One, 6(10), e20688. [More Information]
  • Colvin, E., Susanto, J., Kench, J., Ong, V., Mawson, A., Pinese, M., Chang, D., Rooman, I., O'Toole, S., Segara, D., et al (2011). Retinoid signaling in pancreatic cancer, injury and regeneration. PLoS One, 6(12), e29075 - 1-e29075 - 10. [More Information]
  • Callen, D., Ricciardelli, C., Butler, M., Stapleton, A., Stahl, J., Kench, J., Horsefall, D., Tilley, W., Schulz, R., Nesland, J., et al (2010). Co-expression of the androgen receptor and the transcription factor ZNF652 is related to prostate cancer outcome. Oncology reports, 23(4), 1045-1052.
  • Ricciardelli, C., Bianco-Miotto, T., Jindal, S., Dodd, T., Cohen, P., Marshall, V., Sutherland, P., Samaratunga, H., Kench, J., Dong, Y., et al (2010). Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies. Cancer Epidemiology, Biomarkers and Prevention, 19(7), 1755-1765. [More Information]
  • Talantov, D., Jatkoe, T., Bohm, M., Zhang, Y., Ferguson, A., Stricker, P., Kattan, M., Sutherland, R., Kench, J., Wang, Y., et al (2010). Gene based prediction of clinically localized prostate cancer progression after radical prostatectomy. The Journal of Urology, 184, 1521-1528. [More Information]
  • Bianco-Miotto, T., Chiam, K., Buchanan, G., Jindal, S., Day, T., Thomas, M., Pickering, M., O'Loughlin, M., Ryan, N., Raymond, W., Horvath, L., Kench, J., et al (2010). Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development. Cancer Epidemiology, Biomarkers and Prevention, 19(10), 2611-2622. [More Information]
  • Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S., Hawthorne, W., O'Connell, P., Loudovaris, T., Kay, T., Kulkarni, R., Biankin, A., Kench, J., Gunton, J., et al (2010). Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. Journal of Clinical Investigation, 120(6), 2171-2183. [More Information]
  • Hudson, T., Anderson, W., Aretz, A., Barker, A., Bell, C., Bernabe, R., Bhan, M., Calvo, F., Eerola, I., Gerhard, D., deFazio, A., Kench, J., et al (2010). International network of cancer genome projects. Nature, 464, 993-998. [More Information]
  • Bohm, M., Locke, W., Sutherland, R., Kench, J., Henshall, S. (2009). A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes. Oncogene, 28(43), 3847-3856. [More Information]
  • Milner, K., van der Poorten, D., Xu, A., Bugianesi, E., Kench, J., Lam, K., Chisholm, D., George, J. (2009). Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease. Hepatology, 49(6), 1926-1934. [More Information]
  • Biankin, A., Kench, J., Colvin, E., Segara, D., Scarlett, C., Nguyen, N., Chang, D., Morey, A., Lee, C., Pinese, M., et al (2009). Expression of S100A2 Calcium-Binding Protein Predicts Response to Pancreatectomy for Pancreatic Cancer. Gastroenterology, 137(2), 558-568. [More Information]
  • Chang, D., Johns, A., Merrett, N., Gill, A., Colvin, E., Scarlett, C., Nguyen, N., Leong, R., Cosman, P., Kelly, M., Kench, J., et al (2009). Margin Clearance and Outcome in Resected Pancreatic Cancer. Journal of Clinical Oncology, 27(17), 2855-2862. [More Information]
  • Pinese, M., Scarlett, C., Kench, J., Colvin, E., Segara, D., Henshall, S., Sutherland, R., Biankin, A. (2009). Messina: A Novel Analysis Tool to Identify Biologically Relevant Molecules in Disease. PLoS One, 4(4), e5337-1-e5337-7. [More Information]
  • Nguyen, N., Biankin, A., Leong, R., Chang, D., Cosman, P., Delaney, P., Kench, J., Merrett, N. (2009). Real time intraoperative confocal laser microscopy-guided surgery. Annals of Surgery, 249(5), 735-737. [More Information]
  • Gill, A., Johns, A., Eckstein, R., Samra, J., Kaufman, A., Chang, D., Merrett, N., Cosman, P., Smith, R., Biankin, A., et al (2009). Synoptic reporting improves histopathological assessment of pancreatic resection specimens. Pathology, 41(2), 161-167. [More Information]
  • Ho, L., Kench, J., Handelsman, D., Scheffer, G., Stricker, P., Grygiel, J., Sutherland, R., Henshall, S., Allen, J., Horvath, L. (2008). Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. The Prostate, 68(13), 1421-1429. [More Information]
  • Murphy, N., Scarlett, C., Kench, J., Sum, E., Colvin, E., Susanto, J., Cosman, P., Lee, C., Musgrove, E., Sutherland, R., et al (2008). Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma. British Journal of Cancer, 98(3), 537-541. [More Information]
  • Cua, I., Hui, J., Kench, J., George, J. (2008). Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C. Hepatology, 48(3), 723-731. [More Information]
  • Kench, J., Rasiah, K., Gardiner-Garden, M., Padilla, E., Moller, G., Alles, M., Eggleton, S., Stricker, P., Adamski, J., Sutherland, R. (2008). HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer. Molecular And Cellular Endocrinology, 301`, 89-96. [More Information]
  • Sakko, A., Butler, M., Byers, S., Reinboth, B., Stahl, J., Kench, J., Horvath, L., Sutherland, R., Stricker, P., Henshall, S., et al (2008). Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse. Cancer Epidemiology, Biomarkers and Prevention, 17(9), 2488-2497. [More Information]
  • Poustchi, H., Negro, F., Hui, J., Cua, I., Brandt, L., Kench, J., George, J. (2008). Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. Journal of Hepatology, 48(1), 28-34. [More Information]
  • Heiser, P., Cano, D., Landsman, L., Kim, G., Kench, J., Klimstra, D., Taketo, M., Biankin, A., Hebrok, M. (2008). Stabilization of beta-catenin induces pancreas tumor formation. Gastroenterology, 135(4), 1288-1300. [More Information]
  • van der Poorten, D., Milner, K., Hui, J., Hodge, A., Trenell, M., Kench, J., London, R., Peduto, A., Chisholm, D., George, J. (2008). Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology, 48(2), 449-457. [More Information]
  • di Magliano, M., Biankin, A., Heiser, P., Cano, D., Gutierrez, P., Deramaudt, T., Segara, D., Dawson, A., Kench, J., Henshall, S., et al (2007). Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. PLoS One, 2(11), 1-9. [More Information]
  • Laybutt, D., Preston, A., Akerfeldt, M., Kench, J., Busch, A., Biankin, A., Biden, T. (2007). Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes. Diabetologia: clinical and experimental diabetes and metabolism, 50(4), 752-763. [More Information]
  • Cua, I., Hui, J., Bandara, P., Kench, J., Farrell, G., McCaughan, G., George, J. (2007). Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines. Hepatology, 46(1), 66-73. [More Information]
  • Oakes, S., Robertson, F., Kench, J., Gardiner-Garden, M., Wand, M., Green, J., Ormandy, C. (2007). Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions. Oncogene, 26(4), 543-553. [More Information]
  • Horvath, L., Lelliott, J., Kench, J., Lee, C., Williams, E., Saunders, D., Grygiel, J., Sutherland, R., Henshall, S. (2007). Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer. The Prostate, 67(10), 1081-1090. [More Information]
  • Angulo, P., Hui, J., Marchesini, G., Bugianesi, E., George, J., Farrell, G., Enders, F., Saksena, S., Burt, A., Bida, J., Kench, J., et al (2007). The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology, 45(4), 846-854. [More Information]
  • Rasiah, K., Kench, J., Gardiner-Garden, M., Biankin, A., Golovsky, D., Brenner, P., Kooner, R., O'Neill, G., Turner, J., Delprado, W., Lee, C., Horvath, L., et al (2006). Aberrant neuropeptide Y and macrophage inhibitory cytokine-1 expression are early events in prostate cancer development and are associated with poor prognosis. Cancer Epidemiology, Biomarkers and Prevention, 15(4), 711-716. [More Information]
  • McNeil, C., Sergio, C., Anderson, L., Inman, C., Eggleton, S., Murphy, N., Millar, E., Crea, P., Kench, J., Alles, M., Ormandy, C., Butt, A., et al (2006). c-Myc overexpression and endocrine resistance in breast cancer. Journal of Steroid Biochemistry and Molecular Biology. [More Information]
  • Skalicky, D., Kench, J., Segara, D., Coleman, M., Sutherland, R., Henshall, S., Musgrove, E., Biankin, A. (2006). Cyclin E expression and outcome in pancreatic ductal adenocarcinoma. Cancer Epidemiology, Biomarkers and Prevention, 15(10), 1941-1947. [More Information]
  • Cua, I., Hui, J., Bandara, P., Kench, J., McCaughan, G., George, J. (2006). Is insulin resistance and liver injury in chronic hepatitis C associated with virus-specific alteration in the levels of serum adipocytokines? Journal of Gastroenterology and Hepatology, 21, A22-A22.
  • Cua, I., Kwan, V., Henriquez, M., Kench, J., George, J. (2006). Long term suppressive therapy with pegylated interferon for chronic hepatitis C associated membranoproliferative glomerulonephritis. Gut (English Edition): an international journal of gastroenterology and hepatology, 55(10), 1521-1522. [More Information]
  • Henshall, S., Horvath, L., Quinn, D., Eggleton, S., Grygiel, J., Stricker, P., Biankin, A., Kench, J., Sutherland, R. (2006). Zinc-alpha2-glycoprotein expression as a predictor of metastatic prostate cancer following radical prostatectomy. National Cancer Institute. Journal, 98(19), 1420-1424. [More Information]
  • Bandara, P., George, J., McCaughan, G., Naidoo, D., Lux, O., Salonikas, C., Kench, J., Byth Wilson, K., Farrell, G. (2005). Antioxidant levels in peripheral blood, disease activity and fibrotic stage in chronic hepatitis C. Liver International, 25(3), 518-526. [More Information]
  • Segara, D., Biankin, A., Kench, J., Langusch, C., Dawson, A., Skalicky, D., Gotley, D., Coleman, M., Sutherland, R., Henshall, S. (2005). Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia. Clinical Cancer Research, 11(9), 3587-3596. [More Information]
  • Adams, L., Bulsara, M., Rossi, E., DeBoer, B., Speers, D., George, J., Kench, J., Farrell, G., McCaughan, G., Jeffrey, G. (2005). Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection. Clinical Chemistry (Washington, DC), 51(10), 1867-1873. [More Information]
  • Kumar, U., Farrell, G., Kench, J., George, J. (2005). Hepatic steatosis and the risk of hepatocellular carcinoma in chronic hepatitis C. Journal of Gastroenterology and Hepatology, 20(9), 1395-1400. [More Information]
  • Horvath, L., Henshall, S., Lee, C., Kench, J., Golovsky, D., Brenner, P., O'Neill, G., Kooner, R., Stricker, P., Grygiel, J., et al (2005). Lower levels of nuclear beta-catenin predict for a poorer prognosis in localized prostate cancer. International Journal of Cancer, 113(3), 415-422. [More Information]
  • Kwong, R., Kalish, L., Nguyen, T., Kench, J., Bova, R., Cole, I., Musgrove, E., Sutherland, R. (2005). p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue. Clinical Cancer Research, 11(11), 4107-4116. [More Information]
  • Cachia, A., Eshoo, S., Kench, J., Fung, C., Jones, A., Iredell, J., Don, G. (2005). Synchronous malakoplakia and Whipple's disease. Pathology, 37(4), 315-7. [More Information]
  • Bauskin, A., Brown, D., Junankar, S., Rasiah, K., Eggleton, S., Hunter, M., Liu, T., Smith, D., Kuffner, T., Kench, J., et al (2005). The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome. Cancer Research, 65(6), 2330-2336. [More Information]
  • Hui, J., Hodge, A., Farrell, G., Kench, J., Kriketos, A., George, J. (2004). Beyond Insulin Resistance In Nash: Tnf-Alpha Or Adiponectin? Hepatology, 40(1), 46-54. [More Information]
  • Coverdale, S., Khan, M., Byth Wilson, K., Lin, R., Weltman, M., George, J., Samarasinghe, D., Liddle, C., Farrell, G., Kench, J., Crewe, E. (2004). Effects Of Interferon Treatment Response On Liver Complications Of Chronic Hepatitis C: 9-Year Follow-Up Study. American Journal of Gastroenterology, 99(4), 636-644.
  • Hui, J., Farrell, G., Kench, J., George, J. (2004). High sensitivity C-reactive protein values do not reliably predict the severity of histological change in NAFLD. Hepatology, 39(5), 1458-1459. [More Information]
  • Sud, A., Hui, J., Farrell, G., Bandara, P., Kench, J., Fung, C., Lin, R., Samarasinghe, D., Liddle, C., McCaughan, G., George, J. (2004). Improved Prediction Of Fibrosis In Chronic Hepatitis C Using Measures Of Insulin Resistance In A Probability Index. Hepatology, 39(5), 1239-1247. [More Information]
  • Horvath, L., Henshall, S., Kench, J., Saunders, D., Lee, C., Golovsky, D., Brenner, P., O’Neill, G., Kooner, R., Stricker, P., et al (2004). Membranous Expression Of Secreted Frizzled-Related Protein 4 Predicts For Good Prognosis In Localized Prostate Cancer And Inhibits Pc3 Cellular Proliferation In Vitro. Clinical Cancer Research, 10(2), 615-625.
  • Heinzelmann-Schwarz, V., Gardiner-Garden, M., Henshall, S., Scurry, J., Scolyer, R., Davies, M., Heinzelmann, M., Kalish, L., Bali, A., Kench, J., et al (2004). Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer. Clinical Cancer Research, 10(13), 4427-4436. [More Information]
  • Biankin, A., Kench, J., Biankin, S., Soon, L., Morey, A., Dijkman, F., Coleman, M., Sutherland, R., Henshall, S. (2004). Pancreatic Intraepithelial Neoplasia In Association With Intraductal Papillary Mucinous Neoplasms Of The Pancreas: Implications For Disease Progression And Recurrence. American Journal of Surgical Pathology, 28(9), 1184-1192.
  • Afar, D., Bhaskar, V., Ibsen, E., Breinberg, D., Henshall, S., Kench, J., Drobnjak, M., Powers, R., Wong, M., Evangelista, F., et al (2004). Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Molecular Cancer Therapeutics, 3(8), 921-932. [More Information]
  • Coverdale, S., Samarasinghe, D., Lin, R., Kench, J., Byth Wilson, K., Khan, M., Crewe, E., Liddle, C., George, J., Farrell, G. (2003). Changes in Antipyrine Clearance and Platelet Count, but Not Conventional Liver Tests, Correlate With Fibrotic Change in Chronic Hepatitis C: Value for Predicting Fibrotic Progression. American Journal of Gastroenterology, 98(6), 1384-1390.
  • Hui, J., Sud, A., Farrell, G., Bandara, P., Byth Wilson, K., Kench, J., McCaughan, G., George, J. (2003). Insulin resistance is associated with chronic Hepatitis C and virus infection fibrosis progression. Gastroenterology, 125(6), 1695-1704.
  • Veness, M., Thompson, S., Morgan, G., Shannon, J., Kench, J. (2003). Leptomeningeal carcinomatosis from squamous cell carinoma of the surpaglottic larynx. Journal of Medical Imaging and Radiation Oncology, 11, 325-330.
  • Hui, J., Kench, J., Chitturi, S., Sud, A., Farrell, G., Blyth, K., Hall, P., Khan, M., George, J. (2003). Long term outcomes of cirrhosis in nonalcoholic steatohepatitis compares with hepatitis c. Hepatology, 38(2), 420-427.
  • Biankin, A., Kench, J., Dijkman, F., Biankin, S., Henshall, S. (2003). Molecular pathogenesis of precursor lesions of pancreatic ductal adenocarcinoma. Pathology, 35(1), 14-24. [More Information]
  • Kwong, R., Nguyen, T., Bova, R., Kench, J., Cole, I., Musgrove, E., Henshall, S., Sutherland, R. (2003). Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue. Clinical Cancer Research, 9(10), 3705-3711. [More Information]
  • Lee, D., Chitturi, S., Kench, J., George, J., Fuller, S., Bradstock, K., Lin, R., Wong, K., Young, N. (2003). Transjugular liver biopsy effecting changes in clinical management. Journal of Medical Imaging and Radiation Oncology, 47(2), 117-120. [More Information]
  • Biankin, A., Biankin, S., Kench, J., Morey, A., Lee, C., Head, D., Eckstein, R., Hugh, T., Henshall, S., Sutherland, R. (2002). Aberrant p16INK4A and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. Gut (English Edition): an international journal of gastroenterology and hepatology, 50, 861-868.
  • Biankin, A., Morey, A., Lee, C., Kench, J., Biankin, S., Hook, H., Head, D., Hugh, T., Sutherland, R., Henshall, S. (2002). DPC4/Smad4 Expression and Outcome in Pancreatic Ductal Adenocarcinoma. Journal of Clinical Oncology, 20(23), 4531-4542.
  • Chitturi, S., George, J., Ranjitkumar, S., Kench, J., Benson, W. (2002). Exchange Transfusion for Severe Intrahepatic Cholestasis Associated With Sickle Cell Disease. Journal of Clinical Gastroenterology, 35(4), 362-363.
  • Hui, J., Kench, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., Byth, K., George, J. (2002). Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection. Journal of Gastroenterology and Hepatology, 17(8), 873-881.
  • Chitturi, S., Le, V., Kench, J., Loh, C., George, J. (2002). Gliclazide-Induced Acute Hepatitis with Hypersensitivity Features. Digestive diseases and sciences, 47(5), 1107-1110.
  • Hui, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., George, J., Kench, J., Byth, K. (2002). Hepatic Steatosis in Chronic Hepatitis C Infection. Journal of Gastroenterology and Hepatology, 17(8), 873-881.
  • Lee, C., Biankin, A., Kench, J., Morey, A., Biankin, S., Head, D., Hugh,, T., Henshall, S., Sutherland, A. (2001). Overexpression of p21WAF1/CP1 is an Early Event in the Development of Pancreatic Intraepithelial Neoplasia. Cancer Research, 61, 8830-8837.
  • George, J., Hui, J., Farrell, G., Lin, R., Samarasinghe, D., Kench, J. (2001). Predictors for steatosis and fibrosis in chronic hepatitis C. Journal of Hepatology, 34, 153-153.

Conferences

  • Coverdale, S., Samarasinghe, D., Lin, R., Liddle, C., George, J., Farrell, G., Kench, J., Byth, K., Khan, M., Crewe, E. (2001). Prediction of histological progression in chronic hepatitis C. Asia Pacific Digestive Week 2001, : World Scientific Publishing.

2014

  • McKenzie, P., Delahunt, B., Kench, J., Sikaris, K. (2014). 5-alpha reductase inhibitors and PSA screening for prostate cancer. Pathology, 46(1), 91-92. [More Information]
  • Nagrial, A., Chang, D., Nguyen, N., Johns, A., Chantrill, L., Humphris, J., Chin, V., Samra, J., Gill, A., Pajic, M., Chou, A., Kench, J., Horvath, L., et al (2014). Adjuvant chemotherapy in elderly patients with pancreatic cancer. British Journal of Cancer, 110(2), 313-319. [More Information]
  • Yip, P., Cooper, W., Kohonen-Corish, M., Lin, B., McCaughan, B., Boyer, M., Kench, J., Horvath, L. (2014). Phosphorylated Akt expression is a prognostic marker in early-stage non-small cell lung cancer. Journal of Clinical Pathology, 67(4), 333-340. [More Information]

2013

  • Gzell, C., Kench, J., Stockler, M., Hruby, G. (2013). Biopsy-proven brain metastases from prostate cancer: a series of four cases with review of the literature. International Urology and Nephrology, 45(3), 735-742. [More Information]
  • Cooper, C., O'Toole, S., Kench, J. (2013). Classification, morphology and molecular pathology of premalignant lesions of the pancreas. Pathology, 45(3), 286-304. [More Information]
  • Kench, J., Delahunt, B., Griffiths, D., Humphrey, P., McGowan, T., Trpkov, K., Varma, M., Wheeler, T., Srigley, J. (2013). Dataset for reporting of prostate carcinoma in radical prostatectomy specimens: recommendations from the International Collaboration on Cancer Reporting. Histopathology, 62(2), 203-218. [More Information]
  • Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013). EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology, 66(9), 744-748. [More Information]
  • Coker, D., Kench, J., Ansari, N., Zhou, R., Sandroussi, C. (2013). Hepatobiliary and Pancreatic: Clear cell myomelanotic tumor of ligamentum teres. Journal of Gastroenterology and Hepatology, 28(2), 381-381. [More Information]
  • Chang, D., Jamieson, N., Johns, A., Scarlett, C., Pajic, M., Chou, A., Pinese, M., Humphris, J., Jones, M., Toon, C., Samra, J., Kench, J., Gill, A., et al (2013). Histomolecular Phenotypes and Outcome in Adenocarcinoma of the Ampulla of Vater. Journal of Clinical Oncology, 31(10), 1348-1356. [More Information]
  • Hashemi, S., van der Poorten, D., Barrera Martinez, F., Bandara, P., Lux, O., Kench, J., George, J. (2013). Oxidative stress is closely associated with insulin resistance in genotypes 1 and 3 chronic hepatitis C. Hepatology International, 7(2), 516-523. [More Information]
  • Yip, P., Yu, B., Cooper, W., Selinger, C., Ng, C., Kennedy, C., Kohonen-Corish, M., McCaughan, B., Trent, R., Boyer, M., Kench, J., Horvath, L., O'Toole, S. (2013). Patterns of DNA mutations and ALK Rearrangement in Resected Node Negative Lung Adenocarcinoma. Journal of Thoracic Oncology, 8(4), 408-414. [More Information]
  • McKenzie, P., Delahunt, B., Kench, J., Ross, B., Lam, Q., DeVoss, K., Tran, H., Sikaris, K. (2013). Prostate specific antigen testing: age-related interpretation in early prostate cancer detection. Pathology, 45(4), 343-345. [More Information]
  • Young, J., Ting, K., Li, J., Moller, T., Dunn, L., Lu, Y., Moses, J., Prado-Lourenco, L., Khachigian, L., Ng, M., Lichtenstein, I., Tran, N., Shackel, N., Kench, J., McCaughan, G., Vadas, M., Gamble, J., et al (2013). Regulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood, 122(16), 2911-2919. [More Information]
  • Pang, J., Mahar, A., Shannon, K., Kench, J., Chan, C., Gupta, R. (2013). Reticular and microcystic schwannoma of the parotid gland. Pathology, 45(1), 96-98. [More Information]
  • McKenzie, P., Delahunt, B., Kench, J. (2013). The dilemmas of prostate cancer screening. Medical Journal of Australia, 199(9), 582-584. [More Information]

2012

  • Ramponi, F., Kench, J., Simring, D., Crawford, M., Abadir, E., Harris, J. (2012). Early diagnosis and resection of an asymptomatic leiomyosarcoma of the inferior vena cava prior to caval obstruction. Journal Of Vascular Surgery, 55(2), 525-528. [More Information]
  • Graaf, E., Kench, J., Dilworth, P., Shackel, N., Strasser, S., Joseph, D., Pleass, H., Crawford, M., McCaughan, G., Verran, D. (2012). Grade of Deceased Donor Liver Macrovesicular Steatosis Impacts Graft and Recipient Outcomes More than Donor Risk Index. Journal of Gastroenterology and Hepatology, 27(3), 540-546. [More Information]
  • Savdie, R., Horvath, L., Pe Benito, R., Rasiah, K., Haynes, A., Chatfield, M., Stricker, P., Turner, J., Delprado, W., Henshall, S., Kench, J., et al (2012). High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy. BJU International, 109(12), 1794-1800. [More Information]
  • Biankin, A., Waddell, N., Kassahn, K., Gingras, M., Muthuswamy, L., Johns, A., Miller, D., Wilson, P., Patch, A., Wu, J., Gill, A., Kench, J., Pavlakis, N., Lam, V., Richardson, A., Samra, J., et al (2012). Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature, 491(7424), 399-405. [More Information]
  • Humphris, J., Chang, D., Johns, A., Scarlett, C., Pajic, M., Jones, M., Colvin, E., Nagrial, A., Chin, V., Chantrill, L., Samra, J., Gill, A., Kench, J., et al (2012). The prognostic and predictive value of serum CA19.9 in pancreatic cancer. Annals of Oncology, 23(7), 1713-1722. [More Information]

2011

  • Nguyen, N., Johns, A., Gill, A., Ring, N., Chang, D., Clarkson, A., Merrett, N., Kench, J., Colvin, E., Scarlett, C., et al (2011). Clinical and immunohistochemical features of 34 solid pseudopapillary tumors of the pancreas. Journal of Gastroenterology and Hepatology, 26(2), 267-274. [More Information]
  • Devaney, J., Stirzaker, C., Qu, W., Song, J., Statham, A., Patterson, K., Horvath, L., Tabor, B., Coolen, M., Hulf, T., Kench, J., et al (2011). Epigenetic Deregulation Across Chromosome 2q14.2 Differentiates Normal from Prostate Cancer and Provides a Regional Panel of Novel DNA Methylation Cancer Biomarkers. Cancer Epidemiology, Biomarkers and Prevention, 20(1), 148-159. [More Information]
  • Kwong, R., Scarlett, C., Kalish, L., Cole, I., Kench, J., Sum, E., Musgrove, E., Henshall, S., Lindeman, G., Biankin, A., et al (2011). LMO4 expression in squamous cell carcinoma of the anterior tongue. Histopathology, 58(3), 477-480. [More Information]
  • Yip, P., Kench, J., Rasiah, K., Pe Benito, R., Lee, C., Stricker, P., Henshall, S., Sutherland, R., Horvath, L. (2011). Low AZGPI Expression Predicts for Recurrence in Margin-Positive, Localized Prostate Cancer. The Prostate, 71(15), 1638-1645. [More Information]
  • Scarlett, C., Salisbury, E., Biankin, A., Kench, J. (2011). Precursor lesions in pancreatic cancer: morphological and molecular pathology. Pathology, 43(3), 183-200. [More Information]
  • Kench, J., Clouston, D., Delprado, W., Eade, T., Ellis, D., Horvath, L., Samaratunga, H., Stahl, J., Stapleton, A., Egevad, L., et al (2011). Prognostic factors in prostate cancer. Key elements in structured histopathology reporting of radical prostatectomy specimens. Pathology, 43(5), 410-419. [More Information]
  • Scarlett, C., Colvin, E., Pinese, M., Chang, D., Morey, A., Musgrove, E., Pajic, M., Apte, M., Henshall, S., Sutherland, R., et al (2011). Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction. PLoS One, 6(10), e20688. [More Information]
  • Colvin, E., Susanto, J., Kench, J., Ong, V., Mawson, A., Pinese, M., Chang, D., Rooman, I., O'Toole, S., Segara, D., et al (2011). Retinoid signaling in pancreatic cancer, injury and regeneration. PLoS One, 6(12), e29075 - 1-e29075 - 10. [More Information]

2010

  • Callen, D., Ricciardelli, C., Butler, M., Stapleton, A., Stahl, J., Kench, J., Horsefall, D., Tilley, W., Schulz, R., Nesland, J., et al (2010). Co-expression of the androgen receptor and the transcription factor ZNF652 is related to prostate cancer outcome. Oncology reports, 23(4), 1045-1052.
  • Ricciardelli, C., Bianco-Miotto, T., Jindal, S., Dodd, T., Cohen, P., Marshall, V., Sutherland, P., Samaratunga, H., Kench, J., Dong, Y., et al (2010). Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies. Cancer Epidemiology, Biomarkers and Prevention, 19(7), 1755-1765. [More Information]
  • Talantov, D., Jatkoe, T., Bohm, M., Zhang, Y., Ferguson, A., Stricker, P., Kattan, M., Sutherland, R., Kench, J., Wang, Y., et al (2010). Gene based prediction of clinically localized prostate cancer progression after radical prostatectomy. The Journal of Urology, 184, 1521-1528. [More Information]
  • Bianco-Miotto, T., Chiam, K., Buchanan, G., Jindal, S., Day, T., Thomas, M., Pickering, M., O'Loughlin, M., Ryan, N., Raymond, W., Horvath, L., Kench, J., et al (2010). Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development. Cancer Epidemiology, Biomarkers and Prevention, 19(10), 2611-2622. [More Information]
  • Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S., Hawthorne, W., O'Connell, P., Loudovaris, T., Kay, T., Kulkarni, R., Biankin, A., Kench, J., Gunton, J., et al (2010). Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets. Journal of Clinical Investigation, 120(6), 2171-2183. [More Information]
  • Hudson, T., Anderson, W., Aretz, A., Barker, A., Bell, C., Bernabe, R., Bhan, M., Calvo, F., Eerola, I., Gerhard, D., deFazio, A., Kench, J., et al (2010). International network of cancer genome projects. Nature, 464, 993-998. [More Information]

2009

  • Bohm, M., Locke, W., Sutherland, R., Kench, J., Henshall, S. (2009). A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes. Oncogene, 28(43), 3847-3856. [More Information]
  • Milner, K., van der Poorten, D., Xu, A., Bugianesi, E., Kench, J., Lam, K., Chisholm, D., George, J. (2009). Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease. Hepatology, 49(6), 1926-1934. [More Information]
  • Biankin, A., Kench, J., Colvin, E., Segara, D., Scarlett, C., Nguyen, N., Chang, D., Morey, A., Lee, C., Pinese, M., et al (2009). Expression of S100A2 Calcium-Binding Protein Predicts Response to Pancreatectomy for Pancreatic Cancer. Gastroenterology, 137(2), 558-568. [More Information]
  • Chang, D., Johns, A., Merrett, N., Gill, A., Colvin, E., Scarlett, C., Nguyen, N., Leong, R., Cosman, P., Kelly, M., Kench, J., et al (2009). Margin Clearance and Outcome in Resected Pancreatic Cancer. Journal of Clinical Oncology, 27(17), 2855-2862. [More Information]
  • Pinese, M., Scarlett, C., Kench, J., Colvin, E., Segara, D., Henshall, S., Sutherland, R., Biankin, A. (2009). Messina: A Novel Analysis Tool to Identify Biologically Relevant Molecules in Disease. PLoS One, 4(4), e5337-1-e5337-7. [More Information]
  • Nguyen, N., Biankin, A., Leong, R., Chang, D., Cosman, P., Delaney, P., Kench, J., Merrett, N. (2009). Real time intraoperative confocal laser microscopy-guided surgery. Annals of Surgery, 249(5), 735-737. [More Information]
  • Gill, A., Johns, A., Eckstein, R., Samra, J., Kaufman, A., Chang, D., Merrett, N., Cosman, P., Smith, R., Biankin, A., et al (2009). Synoptic reporting improves histopathological assessment of pancreatic resection specimens. Pathology, 41(2), 161-167. [More Information]

2008

  • Ho, L., Kench, J., Handelsman, D., Scheffer, G., Stricker, P., Grygiel, J., Sutherland, R., Henshall, S., Allen, J., Horvath, L. (2008). Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer. The Prostate, 68(13), 1421-1429. [More Information]
  • Murphy, N., Scarlett, C., Kench, J., Sum, E., Colvin, E., Susanto, J., Cosman, P., Lee, C., Musgrove, E., Sutherland, R., et al (2008). Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma. British Journal of Cancer, 98(3), 537-541. [More Information]
  • Cua, I., Hui, J., Kench, J., George, J. (2008). Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C. Hepatology, 48(3), 723-731. [More Information]
  • Kench, J., Rasiah, K., Gardiner-Garden, M., Padilla, E., Moller, G., Alles, M., Eggleton, S., Stricker, P., Adamski, J., Sutherland, R. (2008). HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer. Molecular And Cellular Endocrinology, 301`, 89-96. [More Information]
  • Sakko, A., Butler, M., Byers, S., Reinboth, B., Stahl, J., Kench, J., Horvath, L., Sutherland, R., Stricker, P., Henshall, S., et al (2008). Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse. Cancer Epidemiology, Biomarkers and Prevention, 17(9), 2488-2497. [More Information]
  • Poustchi, H., Negro, F., Hui, J., Cua, I., Brandt, L., Kench, J., George, J. (2008). Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. Journal of Hepatology, 48(1), 28-34. [More Information]
  • Kench, J., Cosman, P., Merrett, N., Biankin, A. (2008). Pathology and Molecular Biology of Intraductal Papillary Mucinous Neoplasms. In Andrew M. Lowy, Steven D. Leach, Philip Philip (Eds.), Pancreatic Cancer, (pp. 53-64). US: Springer.
  • Heiser, P., Cano, D., Landsman, L., Kim, G., Kench, J., Klimstra, D., Taketo, M., Biankin, A., Hebrok, M. (2008). Stabilization of beta-catenin induces pancreas tumor formation. Gastroenterology, 135(4), 1288-1300. [More Information]
  • van der Poorten, D., Milner, K., Hui, J., Hodge, A., Trenell, M., Kench, J., London, R., Peduto, A., Chisholm, D., George, J. (2008). Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology, 48(2), 449-457. [More Information]

2007

  • di Magliano, M., Biankin, A., Heiser, P., Cano, D., Gutierrez, P., Deramaudt, T., Segara, D., Dawson, A., Kench, J., Henshall, S., et al (2007). Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. PLoS One, 2(11), 1-9. [More Information]
  • Laybutt, D., Preston, A., Akerfeldt, M., Kench, J., Busch, A., Biankin, A., Biden, T. (2007). Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes. Diabetologia: clinical and experimental diabetes and metabolism, 50(4), 752-763. [More Information]
  • Cua, I., Hui, J., Bandara, P., Kench, J., Farrell, G., McCaughan, G., George, J. (2007). Insulin resistance and liver injury in hepatitis C is not associated with virus-specific changes in adipocytokines. Hepatology, 46(1), 66-73. [More Information]
  • Oakes, S., Robertson, F., Kench, J., Gardiner-Garden, M., Wand, M., Green, J., Ormandy, C. (2007). Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions. Oncogene, 26(4), 543-553. [More Information]
  • Horvath, L., Lelliott, J., Kench, J., Lee, C., Williams, E., Saunders, D., Grygiel, J., Sutherland, R., Henshall, S. (2007). Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer. The Prostate, 67(10), 1081-1090. [More Information]
  • Angulo, P., Hui, J., Marchesini, G., Bugianesi, E., George, J., Farrell, G., Enders, F., Saksena, S., Burt, A., Bida, J., Kench, J., et al (2007). The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology, 45(4), 846-854. [More Information]

2006

  • Rasiah, K., Kench, J., Gardiner-Garden, M., Biankin, A., Golovsky, D., Brenner, P., Kooner, R., O'Neill, G., Turner, J., Delprado, W., Lee, C., Horvath, L., et al (2006). Aberrant neuropeptide Y and macrophage inhibitory cytokine-1 expression are early events in prostate cancer development and are associated with poor prognosis. Cancer Epidemiology, Biomarkers and Prevention, 15(4), 711-716. [More Information]
  • McNeil, C., Sergio, C., Anderson, L., Inman, C., Eggleton, S., Murphy, N., Millar, E., Crea, P., Kench, J., Alles, M., Ormandy, C., Butt, A., et al (2006). c-Myc overexpression and endocrine resistance in breast cancer. Journal of Steroid Biochemistry and Molecular Biology. [More Information]
  • Skalicky, D., Kench, J., Segara, D., Coleman, M., Sutherland, R., Henshall, S., Musgrove, E., Biankin, A. (2006). Cyclin E expression and outcome in pancreatic ductal adenocarcinoma. Cancer Epidemiology, Biomarkers and Prevention, 15(10), 1941-1947. [More Information]
  • Cua, I., Hui, J., Bandara, P., Kench, J., McCaughan, G., George, J. (2006). Is insulin resistance and liver injury in chronic hepatitis C associated with virus-specific alteration in the levels of serum adipocytokines? Journal of Gastroenterology and Hepatology, 21, A22-A22.
  • Cua, I., Kwan, V., Henriquez, M., Kench, J., George, J. (2006). Long term suppressive therapy with pegylated interferon for chronic hepatitis C associated membranoproliferative glomerulonephritis. Gut (English Edition): an international journal of gastroenterology and hepatology, 55(10), 1521-1522. [More Information]
  • Henshall, S., Horvath, L., Quinn, D., Eggleton, S., Grygiel, J., Stricker, P., Biankin, A., Kench, J., Sutherland, R. (2006). Zinc-alpha2-glycoprotein expression as a predictor of metastatic prostate cancer following radical prostatectomy. National Cancer Institute. Journal, 98(19), 1420-1424. [More Information]

2005

  • Bandara, P., George, J., McCaughan, G., Naidoo, D., Lux, O., Salonikas, C., Kench, J., Byth Wilson, K., Farrell, G. (2005). Antioxidant levels in peripheral blood, disease activity and fibrotic stage in chronic hepatitis C. Liver International, 25(3), 518-526. [More Information]
  • Segara, D., Biankin, A., Kench, J., Langusch, C., Dawson, A., Skalicky, D., Gotley, D., Coleman, M., Sutherland, R., Henshall, S. (2005). Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia. Clinical Cancer Research, 11(9), 3587-3596. [More Information]
  • Adams, L., Bulsara, M., Rossi, E., DeBoer, B., Speers, D., George, J., Kench, J., Farrell, G., McCaughan, G., Jeffrey, G. (2005). Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection. Clinical Chemistry (Washington, DC), 51(10), 1867-1873. [More Information]
  • Kumar, U., Farrell, G., Kench, J., George, J. (2005). Hepatic steatosis and the risk of hepatocellular carcinoma in chronic hepatitis C. Journal of Gastroenterology and Hepatology, 20(9), 1395-1400. [More Information]
  • Horvath, L., Henshall, S., Lee, C., Kench, J., Golovsky, D., Brenner, P., O'Neill, G., Kooner, R., Stricker, P., Grygiel, J., et al (2005). Lower levels of nuclear beta-catenin predict for a poorer prognosis in localized prostate cancer. International Journal of Cancer, 113(3), 415-422. [More Information]
  • Kwong, R., Kalish, L., Nguyen, T., Kench, J., Bova, R., Cole, I., Musgrove, E., Sutherland, R. (2005). p14ARF protein expression is a predictor of both relapse and survival in squamous cell carcinoma of the anterior tongue. Clinical Cancer Research, 11(11), 4107-4116. [More Information]
  • Cachia, A., Eshoo, S., Kench, J., Fung, C., Jones, A., Iredell, J., Don, G. (2005). Synchronous malakoplakia and Whipple's disease. Pathology, 37(4), 315-7. [More Information]
  • Bauskin, A., Brown, D., Junankar, S., Rasiah, K., Eggleton, S., Hunter, M., Liu, T., Smith, D., Kuffner, T., Kench, J., et al (2005). The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome. Cancer Research, 65(6), 2330-2336. [More Information]

2004

  • Hui, J., Hodge, A., Farrell, G., Kench, J., Kriketos, A., George, J. (2004). Beyond Insulin Resistance In Nash: Tnf-Alpha Or Adiponectin? Hepatology, 40(1), 46-54. [More Information]
  • Coverdale, S., Khan, M., Byth Wilson, K., Lin, R., Weltman, M., George, J., Samarasinghe, D., Liddle, C., Farrell, G., Kench, J., Crewe, E. (2004). Effects Of Interferon Treatment Response On Liver Complications Of Chronic Hepatitis C: 9-Year Follow-Up Study. American Journal of Gastroenterology, 99(4), 636-644.
  • Hui, J., Farrell, G., Kench, J., George, J. (2004). High sensitivity C-reactive protein values do not reliably predict the severity of histological change in NAFLD. Hepatology, 39(5), 1458-1459. [More Information]
  • Sud, A., Hui, J., Farrell, G., Bandara, P., Kench, J., Fung, C., Lin, R., Samarasinghe, D., Liddle, C., McCaughan, G., George, J. (2004). Improved Prediction Of Fibrosis In Chronic Hepatitis C Using Measures Of Insulin Resistance In A Probability Index. Hepatology, 39(5), 1239-1247. [More Information]
  • Horvath, L., Henshall, S., Kench, J., Saunders, D., Lee, C., Golovsky, D., Brenner, P., O’Neill, G., Kooner, R., Stricker, P., et al (2004). Membranous Expression Of Secreted Frizzled-Related Protein 4 Predicts For Good Prognosis In Localized Prostate Cancer And Inhibits Pc3 Cellular Proliferation In Vitro. Clinical Cancer Research, 10(2), 615-625.
  • Heinzelmann-Schwarz, V., Gardiner-Garden, M., Henshall, S., Scurry, J., Scolyer, R., Davies, M., Heinzelmann, M., Kalish, L., Bali, A., Kench, J., et al (2004). Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer. Clinical Cancer Research, 10(13), 4427-4436. [More Information]
  • Biankin, A., Kench, J., Biankin, S., Soon, L., Morey, A., Dijkman, F., Coleman, M., Sutherland, R., Henshall, S. (2004). Pancreatic Intraepithelial Neoplasia In Association With Intraductal Papillary Mucinous Neoplasms Of The Pancreas: Implications For Disease Progression And Recurrence. American Journal of Surgical Pathology, 28(9), 1184-1192.
  • Afar, D., Bhaskar, V., Ibsen, E., Breinberg, D., Henshall, S., Kench, J., Drobnjak, M., Powers, R., Wong, M., Evangelista, F., et al (2004). Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Molecular Cancer Therapeutics, 3(8), 921-932. [More Information]

2003

  • Coverdale, S., Samarasinghe, D., Lin, R., Kench, J., Byth Wilson, K., Khan, M., Crewe, E., Liddle, C., George, J., Farrell, G. (2003). Changes in Antipyrine Clearance and Platelet Count, but Not Conventional Liver Tests, Correlate With Fibrotic Change in Chronic Hepatitis C: Value for Predicting Fibrotic Progression. American Journal of Gastroenterology, 98(6), 1384-1390.
  • Hui, J., Sud, A., Farrell, G., Bandara, P., Byth Wilson, K., Kench, J., McCaughan, G., George, J. (2003). Insulin resistance is associated with chronic Hepatitis C and virus infection fibrosis progression. Gastroenterology, 125(6), 1695-1704.
  • Veness, M., Thompson, S., Morgan, G., Shannon, J., Kench, J. (2003). Leptomeningeal carcinomatosis from squamous cell carinoma of the surpaglottic larynx. Journal of Medical Imaging and Radiation Oncology, 11, 325-330.
  • Hui, J., Kench, J., Chitturi, S., Sud, A., Farrell, G., Blyth, K., Hall, P., Khan, M., George, J. (2003). Long term outcomes of cirrhosis in nonalcoholic steatohepatitis compares with hepatitis c. Hepatology, 38(2), 420-427.
  • Biankin, A., Kench, J., Dijkman, F., Biankin, S., Henshall, S. (2003). Molecular pathogenesis of precursor lesions of pancreatic ductal adenocarcinoma. Pathology, 35(1), 14-24. [More Information]
  • Kwong, R., Nguyen, T., Bova, R., Kench, J., Cole, I., Musgrove, E., Henshall, S., Sutherland, R. (2003). Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue. Clinical Cancer Research, 9(10), 3705-3711. [More Information]
  • Lee, D., Chitturi, S., Kench, J., George, J., Fuller, S., Bradstock, K., Lin, R., Wong, K., Young, N. (2003). Transjugular liver biopsy effecting changes in clinical management. Journal of Medical Imaging and Radiation Oncology, 47(2), 117-120. [More Information]

2002

  • Biankin, A., Biankin, S., Kench, J., Morey, A., Lee, C., Head, D., Eckstein, R., Hugh, T., Henshall, S., Sutherland, R. (2002). Aberrant p16INK4A and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. Gut (English Edition): an international journal of gastroenterology and hepatology, 50, 861-868.
  • Biankin, A., Morey, A., Lee, C., Kench, J., Biankin, S., Hook, H., Head, D., Hugh, T., Sutherland, R., Henshall, S. (2002). DPC4/Smad4 Expression and Outcome in Pancreatic Ductal Adenocarcinoma. Journal of Clinical Oncology, 20(23), 4531-4542.
  • Chitturi, S., George, J., Ranjitkumar, S., Kench, J., Benson, W. (2002). Exchange Transfusion for Severe Intrahepatic Cholestasis Associated With Sickle Cell Disease. Journal of Clinical Gastroenterology, 35(4), 362-363.
  • Hui, J., Kench, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., Byth, K., George, J. (2002). Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection. Journal of Gastroenterology and Hepatology, 17(8), 873-881.
  • Chitturi, S., Le, V., Kench, J., Loh, C., George, J. (2002). Gliclazide-Induced Acute Hepatitis with Hypersensitivity Features. Digestive diseases and sciences, 47(5), 1107-1110.
  • Hui, J., Farrell, G., Lin, R., Samarasinghe, D., Liddle, C., George, J., Kench, J., Byth, K. (2002). Hepatic Steatosis in Chronic Hepatitis C Infection. Journal of Gastroenterology and Hepatology, 17(8), 873-881.

2001

  • Lee, C., Biankin, A., Kench, J., Morey, A., Biankin, S., Head, D., Hugh,, T., Henshall, S., Sutherland, A. (2001). Overexpression of p21WAF1/CP1 is an Early Event in the Development of Pancreatic Intraepithelial Neoplasia. Cancer Research, 61, 8830-8837.
  • Coverdale, S., Samarasinghe, D., Lin, R., Liddle, C., George, J., Farrell, G., Kench, J., Byth, K., Khan, M., Crewe, E. (2001). Prediction of histological progression in chronic hepatitis C. Asia Pacific Digestive Week 2001, : World Scientific Publishing.
  • George, J., Hui, J., Farrell, G., Lin, R., Samarasinghe, D., Kench, J. (2001). Predictors for steatosis and fibrosis in chronic hepatitis C. Journal of Hepatology, 34, 153-153.

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