Dr John Kipritidis


Website CT ventilation imaging (CT-VI) at the Radiation Physics Laboratory

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Biographical details

I am a Cancer Institute NSW Early Career Fellow, working at the Radiation Physics Laboratory with Prof. Paul Keall. I am spearheading the development of a novel functional lung imaging technology, computed tomography ventilation imaging (CT-VI) that could enable improved treatment outcomes for 10,000+ lung cancer radiotherapy patients each year.

My first postdoctoral role was as Assistant Professor at Kyoto University (2009-2010), which followed on from a PhD in Plasma Physics at the University of Sydney (2007-2009). This work focused on nuclear emission spectroscopy of small-scale fusion reactors, which inspired my interest in the humane applications of particle accelerator technology and my transition into the medical imaging field. Since joining the Radiation Physics Laboratory in 2012, I have been developing an upward trajectory in medical imaging, contributing to 7 peer-review articles in international medical physics journals, including 2 as first author and one as senior author.

Research interests

My main research interests are in the fields of respiration-correlated computed tomography ('4D-CT') image reconstruction and analysis, deformable image registration, and functional quantification for lung cancer radiotherapy. My goal as a Cancer Institute NSW Early Career Fellow is to shed new light on functional radiotoxicity in the treatment of lung cancer, and to inspire new treatment paradigms that spare irradiation of healthy lung. I also have an interest in improving 4D-CT image quality through better image acquisition protocols and iterative reconstruction techniques.I am passionate about this work as it has the potential for near-term clinical translation that could lead to more accurate tumor targeting in lung cancer radiotherapy, with better survival and fewer treatment-induced side effects.

I am passionate about this work as it has the potential for near-term clinical translation that could lead to more accurate tumor targeting in lung cancer radiotherapy, with better survival and fewer treatment-induced side effects.

Selected grants

2014

  • On-line ventilation imaging to reduce toxicity in lung cancer radiotherapy; Kipritidis J; Cancer Institute New South Wales/Early Career Fellowship.

Selected publications

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Book Chapters

  • Kajiwara, T., Masuda, K., Kipritidis, J., Yamagaki, Y., Nagasaki, K. (2012). Measurement of Spatial Distributions of Fusion Reactions in an Inertial Electrostatic Confinement Fusion Device Driven by a Ring-Shaped Magnetron Ion Source. In Takeshi Yao (Eds.), Zero-Carbon Energy Kyoto 2011, (pp. 255-260). Tokyo, Japan: Springer.

Journals

  • Shieh, C., Kipritidis, J., O'Brien, R., Kuncic, Z., Keall, P. (2014). Image quality in thoracic 4D cone-beam CT: a sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing. Medical Physics, 41(4), 041912-1-041912-18.
  • O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2014). Optimizing 4DCBCT projection allocation to respiratory bins. Physics in Medicine and Biology, 59(19), 5631-5649. [More Information]
  • O'Brien, R., Cooper, B., Kipritidis, J., Shieh, C., Keall, P. (2014). Respiratory motion guided four dimensional cone beam computed tomography: Encompassing irregular breathing. Physics in Medicine and Biology, 59(3), 579-595. [More Information]
  • Kipritidis, J., Siva, S., Hofman, M., Callahan, J., Hicks, R., Keall, P. (2014). Validating and improving CT ventilation imaging by correlating with ventilation 4D-PET/CT using 68Ga-labeled nanoparticles. Medical Physics, 41(1), 011910-1-011910-12. [More Information]
  • Kipritidis, J., Masuda, K., Kajiwara, T., Yamagaki, Y., Nagasaki, K. (2011). Modeling the time variation of beam-grid fusion reaction rates in an Inertial Electrostatic Confinement device driven by a ring-shaped magnetron ion source. Plasma Physics and Controlled Fusion, 53(4), 1-16. [More Information]
  • Masuda, K., Nakagawa, T., Kipritidis, J., Kajiwara, T., Yamagaki, Y., Zen, H., Yoshikawa, K., Nagasaki, K. (2010). Cathode grid current dependence of D(d, n) 3He reaction rates in an inertial electrostatic confinement device driven by a ring-shaped magnetron ion source. Plasma Physics and Controlled Fusion, 52(9), 1-15. [More Information]
  • Kipritidis, J., Khachan, J. (2009). Application of Doppler spectroscopy in H2 to the prediction of experimental D(d,n)3He reaction rates in an inertial electrostatic confinement device. Physical Review E (Statistical, Nonlinear, and Soft Matter Physics), 79(2), 026403-1-026403-8. [More Information]
  • Kipritidis, J., Khachan, J., Fitzgerald, M., Shrier, O. (2008). Absolute densities of energetic hydrogen ion species in an abnormal hollow cathode discharge. Physical Review E (Statistical, Nonlinear, and Soft Matter Physics), 77(6), 066405-1-066405-9. [More Information]
  • Kipritidis, J., Fitzgerald, M., Khachan, J. (2007). Spectroscopic determination of electron energies in a discharge of atomic H produced by a monoenergetic electron beam. Journal of Physics D: Applied Physics, 40(17), 5170-5176.

Conferences

  • Kipritidis, J., Masuda, K., Kajiwara, T., Yamagaki, Y., Nagasaki, K. (2012). Uncovering the mechanism for time-varying fusion rates in RD-MIS IEC. APP Research Seminar.
  • Masuda, K., Nakagawa, T., Kipritidis, J., Kajiwara, T., Yamagaki, Y., Zen, H., Nagasaki, K., Yoshikawa, K. (2010). IECF driven by RS-MIS: Experimental NPR and motivation for proton collimation. The Atomic Energy Society of Japan (AESJ) Meeting.
  • Kipritidis, J., Khachan, J., Masuda, K. (2009). Pulsed IEC: optical diagnostics and numerical modelling. 11th US-Japan Annual Workshop on Inertial Electrostatic Confinement Fusion, Wisconsin, USA: Fusion Technology Institute.
  • Kipritidis, J., Khachan, J. (2008). Doppler spectroscopy on an IEC device in hydrogen: Predicting experimental rates of D(d,n)3He fusion. 10th US-Japan Workshop on Inertial Electrostatic Confinement Fusion.

2014

  • Shieh, C., Kipritidis, J., O'Brien, R., Kuncic, Z., Keall, P. (2014). Image quality in thoracic 4D cone-beam CT: a sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing. Medical Physics, 41(4), 041912-1-041912-18.
  • O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2014). Optimizing 4DCBCT projection allocation to respiratory bins. Physics in Medicine and Biology, 59(19), 5631-5649. [More Information]
  • O'Brien, R., Cooper, B., Kipritidis, J., Shieh, C., Keall, P. (2014). Respiratory motion guided four dimensional cone beam computed tomography: Encompassing irregular breathing. Physics in Medicine and Biology, 59(3), 579-595. [More Information]
  • Kipritidis, J., Siva, S., Hofman, M., Callahan, J., Hicks, R., Keall, P. (2014). Validating and improving CT ventilation imaging by correlating with ventilation 4D-PET/CT using 68Ga-labeled nanoparticles. Medical Physics, 41(1), 011910-1-011910-12. [More Information]

2012

  • Kajiwara, T., Masuda, K., Kipritidis, J., Yamagaki, Y., Nagasaki, K. (2012). Measurement of Spatial Distributions of Fusion Reactions in an Inertial Electrostatic Confinement Fusion Device Driven by a Ring-Shaped Magnetron Ion Source. In Takeshi Yao (Eds.), Zero-Carbon Energy Kyoto 2011, (pp. 255-260). Tokyo, Japan: Springer.
  • Kipritidis, J., Masuda, K., Kajiwara, T., Yamagaki, Y., Nagasaki, K. (2012). Uncovering the mechanism for time-varying fusion rates in RD-MIS IEC. APP Research Seminar.

2011

  • Kipritidis, J., Masuda, K., Kajiwara, T., Yamagaki, Y., Nagasaki, K. (2011). Modeling the time variation of beam-grid fusion reaction rates in an Inertial Electrostatic Confinement device driven by a ring-shaped magnetron ion source. Plasma Physics and Controlled Fusion, 53(4), 1-16. [More Information]

2010

  • Masuda, K., Nakagawa, T., Kipritidis, J., Kajiwara, T., Yamagaki, Y., Zen, H., Yoshikawa, K., Nagasaki, K. (2010). Cathode grid current dependence of D(d, n) 3He reaction rates in an inertial electrostatic confinement device driven by a ring-shaped magnetron ion source. Plasma Physics and Controlled Fusion, 52(9), 1-15. [More Information]
  • Masuda, K., Nakagawa, T., Kipritidis, J., Kajiwara, T., Yamagaki, Y., Zen, H., Nagasaki, K., Yoshikawa, K. (2010). IECF driven by RS-MIS: Experimental NPR and motivation for proton collimation. The Atomic Energy Society of Japan (AESJ) Meeting.

2009

  • Kipritidis, J., Khachan, J. (2009). Application of Doppler spectroscopy in H2 to the prediction of experimental D(d,n)3He reaction rates in an inertial electrostatic confinement device. Physical Review E (Statistical, Nonlinear, and Soft Matter Physics), 79(2), 026403-1-026403-8. [More Information]
  • Kipritidis, J., Khachan, J., Masuda, K. (2009). Pulsed IEC: optical diagnostics and numerical modelling. 11th US-Japan Annual Workshop on Inertial Electrostatic Confinement Fusion, Wisconsin, USA: Fusion Technology Institute.

2008

  • Kipritidis, J., Khachan, J., Fitzgerald, M., Shrier, O. (2008). Absolute densities of energetic hydrogen ion species in an abnormal hollow cathode discharge. Physical Review E (Statistical, Nonlinear, and Soft Matter Physics), 77(6), 066405-1-066405-9. [More Information]
  • Kipritidis, J., Khachan, J. (2008). Doppler spectroscopy on an IEC device in hydrogen: Predicting experimental rates of D(d,n)3He fusion. 10th US-Japan Workshop on Inertial Electrostatic Confinement Fusion.

2007

  • Kipritidis, J., Fitzgerald, M., Khachan, J. (2007). Spectroscopic determination of electron energies in a discharge of atomic H produced by a monoenergetic electron beam. Journal of Physics D: Applied Physics, 40(17), 5170-5176.

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