Professor John Rasko

AO
Professor
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology

Telephone +61 2 9565 6100
Fax +61 2 9565 6101

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Biographical details

BSc(Med), MBBS(Hons), PhD, FRCPA, FRACP Director, Cell and Molecular Therapies, Royal Prince Alfred Hospital Head, Gene & Stem Cell Therapy, Centenary Institute Professor, Sydney Medical School, University of Sydney

Research interests

John Rasko is a clinical hematologist, pathologist and scientist with a productive track record in gene and stem cell therapy, experimental haematology and molecular biology. In over 150 publications he has contributed to the understanding of stem cells and haemopoiesis, gene transfer technologies, oncogenesis, human aminoacidurias and non-coding RNAs.

He serves on Hospital, state and national bodies including Chair of GTTAC, Office of the Gene Technology Regulator – responsible for regulating all genetically-modified organisms in Australia - and Chair of the Advisory Committee on Biologicals, Therapeutic Goods Administration. Contributions to scientific organisations include co-founding (2000) and past-President (2003-5) of the Australasian Gene Therapy Society; Vice President, International Society for Cellular Therapy (2008-12) and founder (2009) ISCT-Australia; Scientific Advisory Committees and Board member for philanthropic foundations; and several Ethics Committees. He is the recipient of national (RCPA, RACP, ASBMB) and international awards in recognition of his commitment to excellence in medical research, including appointment as an Officer of the Order of Australia.

He serves on Hospital, state and national bodies including Chair of GTTAC, Office of the Gene Technology Regulator ? responsible for regulating all genetically-modified organisms in Australia - and Chair of the Advisory Committee on Biologicals, Therapeutic Goods Administration. Contributions to scientific organisations include co-founding (2000) and past-President (2003-5) of the Australasian Gene Therapy Society; Vice President, International Society for Cellular Therapy (2008-12) and founder (2009) ISCT-Australia; Scientific Advisory Committees and Board member for philanthropic foundations; and several Ethics Committees. He is the recipient of national and international awards in recognition of his commitment to excellence in medical research, including appointment as an Officer of the Order of Australia.

Teaching and supervision

John Rasko has supervised over a dozen successful postgraduate students for their degress, some of whom now head their own laboratories. He delivers regular lectures in the Faculties of Science and Medicine as well as a popular introductory lecture in Haematology for the Central Clinical School. He mentors postdoctoral researchers for career development, and Haematology trainees for the RACP/RCPA. He is a widely-sought speaker internationally and nationally for seminars and the media in bringing research to a broader audience.

Selected grants

2014

  • Consequences of CTCF haploinsufficiency in endometrial carcinoma; Rasko J, Mardis E, Adams D; Cancer Council New South Wales/Research Project Grants.
  • Consequences of CTCF mutation in acute lymphoblastic leukaemia; Rasko J, Bailey C, Adams P; Cancer Council New South Wales/Research Project Grants.
  • Intron retention regulation in granulopoiesis and leukaemia; Rasko J, Ritchie W; National Health and Medical Research Council (NHMRC)/Project Grants.

2013

  • Leica PowerMosaic plus microsope upgrade for flexible, high-resolution slide scanning; Gamble J, McCaughan G, Feng C, Fazekas B, Weninger W, Shackel N, Bertolino P, Lovelace M, Saunders B, Armati P, Pollard J, Pai S, Arnold J, Triccas J, Goldsbury C, Bailey C, Mrass P, Rasko J, Biro M; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2012

  • Development of a treatment algorithm for kinase inhibitor therapy in CML; Rasko J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Characterising a unique substrate for expansion and differentiation of mesenchymal stromal cells for use in regenerative medicine; Rasko J, Macpherson J, Macpherson J; Sir Zelman Cowen Universities Fund/Blue Sky Research Grant.
  • Designer DNA-binding proteins targeting methylated DNA for research and therapeutic purposes; Mackay J, Segal D, Rasko J; National Health and Medical Research Council (NHMRC)/Project Grants.

2011

  • The small animal bioimager; Halliday G, Hambley T, Zreiqat H, Richardson D, Holst J, Rasko J, Byrne S, Dong Q, Hong A, Lyons G; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • automated storage, retrieval, and UV imaging system; Jormakka M, Gamble J, Semsarian C, Rasko J, Vadas M, Xia P, Gorrell M, Clarke R, Holst J, Church W; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The role of small non-coding RNAs (snc RNAs) in alternative splicing; Rasko J; Cancer Council New South Wales/Research Project Grants.
  • Dissecting the muli-component machine that controls chromatin architecture; Rasko J; Cancer Council New South Wales/Research Project Grants.

2010

  • High speed 3D live cell imaging of cancer genesis, growth, metastasis and death.; Weninger W, Vadas M, Richardson D, Fazekas B, Gamble J, McCaughan G, Rasko J, Shackel N, Haass N; Cancer Institute New South Wales/Equipment Grant.
  • Gene therapy, stress haematopoiesis and the risk of malignancy; Alexander I, Kuchel P, Rasko J, Alexander S, McCormack M, Thrasher A, Ginn S; National Health and Medical Research Council (NHMRC)/Project Grants.
  • A surrogate metabolic assay for obsessive-compulsive disorder; Rasko J; DVC Research/Bridging Support Grant.
  • Next-generation high-speed flow cytometric cell sorter; Fazekas B, King N, Simpson S, Britton W, Campbell I, Vadas M, Grau G, Weninger W, Christopherson R, Gamble J, Rasko J, McCaughan G, Xia P, Beale P, Holst J, Haass N, Combes V, Saunders B, Byrne S, West N, Gorrell M, Bertolino P, Bowen D, Warner F, Seth D, Grimshaw M, Jolly C, Martiniello-Wilks R, Mrass P, Lyons G, Sword G; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2009

  • Core Resource Facility - application for 7-laser flow cytometer and high content bioimaging system to enhance capabilities and throughput for the NSW Advanced Cytometry Facility; King N, Vadas M, Campbell I, Grau G, Britton W, Fazekas B, Richardson D, Halliday G, Christopherson R, Gamble J, Mason R, Rasko J, McCaughan G, Weninger W, Xia P, Gorrell M, Holst J, Pile A, Sword G, McArthur C, Dong Q, Haass N, Sharland A, Saunders B, Triccas J, Norris J, Bertolino P, Bowen D, Sze D; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Dissecting BORIS function in neoplasia; Rasko J, Holst J; Cancer Council New South Wales/Research Project Grants.
  • Multi-photon microscope for intravital imaging; Weninger W, Vadas M, Hogg P, Norris M, Fazekas B, Haass N, Clarke S, Halliday G, Rasko J, Holst J, McCaughan G, Allen J, Gamble J, Dong Q, Byrne S, Richardson D; Cancer Institute New South Wales/Equipment Grant.
  • Inverted Multiphoton Intravital Microscope; Weninger W, Gorrell M, Halliday G, Jones C, Fazekas B, Richardson D, Clarke S, Gamble J, Bertolino P, Vadas M, Dong Q, Rasko J, Holst J, McCaughan G, Byrne S, Saunders B, Triccas J, Haass N; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2008

  • Tri-modal Targeted Stem Cell Gene Therapy for Prostate Cancer Metastases; Martiniello-Wilks R, Rasko J; Prostate Cancer Foundation of Australia/Project Grants.
  • Amino acids as nutrients - the molecular basis of amino acid absorption in kidney and intestine; Broer S, Rasko J; Australian Research Council (ARC)/Discovery Projects (DP).
  • Regulation of Erythyroid Cell differentation by microRNAs; Rasko J, Wickrema A, Wickrema A; DVC Research/International Visiting Research Fellowship (IVRF).
  • Dissecting BORIS Function in Neoplasia; Rasko J, Holst J; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • PhD Scholarship investigating Liver Metastatic Cancer; Rasko J; Australian Rotary Health Research Fund/Research Grant.
  • Analysis of the Wnt signalling pathway in cancer; Rasko J, Holst J; Cancer Institute New South Wales/Research Grant.
  • MicroRNAs in primate haemopoiesis; Rasko J; Leukaemia Foundation of Australia/Research Grant.
  • Non-coding gene control of myelopoiesis; Rasko J; Leukaemia Foundation of Australia/Research Grant.
  • The role of CTCF and BORIS transcription factors in cancer; Rasko J; Sydney Cancer Centre Foundation/Cancer Research Grants Program.

2006

  • Diseases of amino acid transport: genetic, molecular and biochemical studies; Rasko J, Cavanaugh J, Broer S; National Health and Medical Research Council (NHMRC)/Project Grants.

2005

  • Micro RNAs in normal and neoplastic myelopoiesis; Rasko J, Martin D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • FACS Aria for the University of Sydney Flow Cytometry Facility; King N, Pollard J, Rasko J, Lovicu F, Bishop A, Bertolino P, Briscoe H, Gillies M, Madigan M, McAvoy J, Murphy C, Balcar V, Armour C, Hughes M, Reeve V, Christopherson R, Halliday G, Christie M, Pollock C, McCaughan G, Gorrell M, Dong Q, Abendroth A, Menzies S, Barnetson R, Byrne S, Hunt N, Hambly B, Cook D, Mason R, Day M, Black J; University of Sydney/Equipment Grant.
  • Small animal whole body IVIS imaging system 50 series & assessories; Rasko J; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The role of neutral amino acid transport in normal physiology; Rasko J, Bröer S, Halliday G, Pollard J, Broeer S; Australian Research Council (ARC)/Discovery Projects (DP).

2004

  • Basic mechanism of spontaneous tolerance of liver allografts in a rat model; Wang C, Bishop A, McCaughan G, Rasko J, Sharland A; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Zinc finger transcription factors in human cancers: normal and aberrant functions; Iland H, Rasko J; Cure Cancer Australia Foundation/Research Support.
  • Growth factor-induced signalling pathways involved in regulation of lens cell behaviour; Lovicu F, Rasko J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Verdi V2 DPSS laser system; Fazekas B, Rasko J, Britton W, Tangye S, Brink R, Basten A; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2003

  • RNA splicing: factors and mechanisms; Morris B, Rasko J; Australian Research Council (ARC)/Discovery Projects (DP).

2002

  • Epigenetic silencing of retroelements in mammalian stem cells: a role for RNA interference?; Rasko J, Martin D; National Health and Medical Research Council (NHMRC)/Project Grants.

2000

  • Improving gene transfer into haemopoietic cells; Rasko J, Mackenzie K; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Ritchie, W., Rasko, J., Flamant, S. (2013). MicroRNA Target Prediction and Validation. In Ulf Schmitz, Olaf Wolkenhauer, Julio Vera (Eds.), MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools, (pp. 39-53). Dordrecht: Springer.
  • Ritchie, W., Rasko, J. (2012). Integrated miRNA expression analysis and target prediction. In Jian-Bing Fan (Eds.), Methods in Molecular Biology: Next-Generation MicroRNA Expression Profiling Technology: Methods and Protocols, (pp. 289-293). New York, United States: Springer.
  • O'Sullivan, G., Ankeny, R., Rasko, J. (2006). Is Inheritable Genetic Modification the New Dividing Line?? In John E. J. Rasko; Gabrielle M. O'Sullivan; Rachel A. Ankeny (Eds.), The Ethics of Inheritable Genetic Modification: A Dividing Line?, (pp. 1-15). Cambridge, UK: Cambridge University Press.
  • Rasko, J., Jolly, D. (2006). The science of inheritable genetic modification. In John E. J. Rasko; Gabrielle M. O'Sullivan; Rachel A. Ankeny (Eds.), The Ethics of Inheritable Genetic Modification: A Dividing Line?, (pp. 17-33). Cambridge, UK: Cambridge University Press.
  • Rasko, J., Celermajer, D. (2000). Gene therapy for vascular diseases. In RT Dean, D Kelly (Eds.), Atherosclerosis: Gene Expression, Cell Interactions, and Oxidation, (pp. 112-136). Oxford: Oxford University Press.

Journals

  • Lim, S., Becker, T., Chua, W., Caixeiro, N., Ng, W., Kienzle, N., Tognela, A., Lumba, S., Rasko, J., de Souza, P., et al (2014). Circulating Tumour Cells and Circulating Free Nucleic Acid as Prognostic and Predictive Biomarkers in Colorectal Cancer. Cancer Letters, 346, 24-33. [More Information]
  • Marshall, A., Bailey, C., Rasko, J. (2014). CTCF and BORIS in genome regulation and cancer. Current Opinion in Genetics & Development, 24C, 8-15. [More Information]
  • Gordon, J., Wong, J., Rasko, J. (2013). MicroRNAs in myeloid malignancies. British Journal of Haematology, 162(2), 162-176. [More Information]
  • Gao, D., Middleton, R., Rasko, J., Ritchie, W. (2013). miREval 2.0: a web tool for simple microRNA prediction in genome sequences. Bioinformatics, 29(24), 3225-3226. [More Information]
  • Levesque, J., Winkler, I., Rasko, J. (2013). Nichotherapy for stem cells: There goes the neighborhood. BioEssays, 35(3), 183-190. [More Information]
  • Larkin, T., Pages, G., Chapman, B., Rasko, J., Kuchel, P. (2013). NMR q-space analysis of canonical shapes of human erythrocytes: stomatocytes, discocytes, spherocytes and echinocytes. European Biophysics Journal, 42(1), 3-16. [More Information]
  • Wong, J., Ritchie, W., Ebner, O., Selbach, M., Wong, J., Huang, Y., Gao, D., Pinello, N., Gonzalez, M., Baidya, K., Thoeng, A., Khoo, T., Bailey, C., Holst, J., Rasko, J. (2013). Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation. Cell, 154(3), 583-595. [More Information]
  • Khoo, T., Xiros, N., Guan, F., Orellana, D., Holst, J., Joshua, D., Rasko, J. (2013). Performance evaluation of the Abbott CELL-DYN Emerald for use as a bench-top analyzer in a research setting. International Journal of Laboratory Hematology, 35(4), 447-456. [More Information]
  • Wang, K., Tiffen, J., Bailey, C., Lehman, M., Ritchie, W., Fazli, L., Metierre, C., Feng, Y., Li, E., Gleave, M., Rasko, J., Holst, J., et al (2013). Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. National Cancer Institute. Journal, 105(19), 1463-1473. [More Information]
  • Tiffen, J., Bailey, C., Marshall, A., Metierre, C., Feng, Y., Wang, K., Watson, S., Holst, J., Rasko, J. (2013). The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. International Journal of Cancer, 133(7), 1603-1614. [More Information]
  • Ritchie, W., Gao, D., Rasko, J. (2012). Defining and providing robust controls for microRNA prediction. Bioinformatics, 28(8), 1058-1061. [More Information]
  • Wang, Q., Bailey, C., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M., Hendy, S., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2011). Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression. Cancer Research, 71(24), 7525-7536. [More Information]
  • Macpherson, J., Rasko, J. (2011). Cellular therapy in the Asia-Pacific region. A guide for the future pathologist. Pathology, 43(6), 616-626. [More Information]
  • Rasko, J. (2011). Future Path: frontiers of molecular and cellular pathology. Pathology, 43(6), 523-524. [More Information]
  • Both, G., Alexander, I., Fletcher, S., Nicolson, T., Rasko, J., Wilton, S., Symonds, G. (2011). Gene therapy: therapeutic applications and relevance to pathology. Pathology, 43(6), 642-656. [More Information]
  • Herbert, K., Levesque, J., Mills, A., Gottlieb, D., Cooney, J., Szer, J., Rasko, J., To, L. (2011). How we mobilize haemopoietic stem cells. Internal Medicine Journal, 41(8), 588-594. [More Information]
  • Balamatsias, D., Kong, A., Waters, J., Sriratana, A., Gurung, R., Bailey, C., Rasko, J., Tiganis, T., Macaulay, S., Mitchell, C. (2011). Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes. Journal of Biological Chemistry, 286(50), 43229-43240. [More Information]
  • Broer, A., Juelich, T., Vanslambrouck, J., Tietze, N., Solomon, P., Holst, J., Bailey, C., Rasko, J., Broer, S. (2011). Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. Journal of Biological Chemistry, 286(30), 26638-26651. [More Information]
  • Bailey, C., Ryan, R., Theong, A., Ng, C., King, K., Vanslambrouck, J., Auray-Blais, C., Vandenberg, R., Bröer, S., Rasko, J. (2011). Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. Journal of Clinical Investigation, 121(1), 446-453. [More Information]
  • To, L., Levesque, J., Herbert, K., Winkler, I., Bendall, L., Hiwase, D., Antonenas, V., Rice, A., Gottlieb, D., Mills, A., Rasko, J., et al (2011). Mobilisation strategies for normal and malignant cells. Pathology, 43(6), 547-565. [More Information]
  • Power, C., Rasko, J. (2011). Promises and challenges of stem cell research for regenerative medicine. Annals of Internal Medicine, 155(10), 706-713. [More Information]
  • Choi, P., Rasko, J. (2011). The challenge of investigating thrombocytopenia. Medicine Today, 12(2), 26-35.
  • Holst, J., Rasko, J. (2011). The use of retroviral vectors for gene transfer into hematopoietic stem cells. Methods in Enzymology, 420, 82-100. [More Information]
  • Power, C., Rasko, J. (2011). Will Cell Reprogramming Resolve the Embryonic Stem Cell Controversy? A Narrative Review. Annals of Internal Medicine, 155(2), 114-121. [More Information]
  • Rasko, J. (2010). A gene therapy renaissance? Journal of Gastroenterology and Hepatology, 25(5), 848-850. [More Information]
  • Khalafallah, A., Dennis, A., Bates, J., Bates, G., Smith, L., Ball, M., Seaton, D., Brain, T., Rasko, J. (2010). A prospective randomized, controlled trial of intravenous versus oral iron for moderate iron deficiency anaemia of pregnancy. Journal of Internal Medicine, 268(3), 286-295. [More Information]
  • Sen, S., Merchan, J., Dean, J., Li, M., Gavin, M., Silver, M., Tkebuchava, T., Yoon, Y., Rasko, J., Aikawa, R. (2010). Autologous transplantation of endothelial progenitor cells genetically modified by adeno-associated viral vector delivering insulin-like growth factor-1 gene after myocardial infarction. Human Gene Therapy, 21(10), 1327-1334. [More Information]
  • Gunter, K., Caplan, A., Mason, C., Salzman, R., Janssen, W., Nichols, K., Bouzas, L., Lanza, F., Levine, B., Rasko, J., et al (2010). Cell therapy medical tourism: Time for action. Cytotherapy, 12(8), 965-968. [More Information]
  • Einecke, G., Kayser, D., Vanslambrouck, J., Sis, B., Reeve, J., Mengel, M., Famulski, K., Bailey, C., Rasko, J., Halloran, P. (2010). Loss of solute carriers in T cell-mediated rejection in mouse and human kidneys: an active epithelial injury-repair response. American Journal Of Transplantation, 10(10), 2241-2251. [More Information]
  • Tiffen, J., Bailey, C., Ng, C., Rasko, J., Holst, J. (2010). Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo. Molecular Cancer, 9, 299-1-299-8. [More Information]
  • Flamant, S., Ritchie, W., Guilhot, J., Holst, J., Bonnet, M., Chomel, J., Guilhot, F., Turhan, A., Rasko, J. (2010). Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia. Haematologica: the hematology journal, 95(8), 1325-1333. [More Information]
  • Tang, C., Russell, P., Martiniello-Wilks, R., Rasko, J., Khatri, A. (2010). Nanoparticles and Cellular Carriers - Allies in Cancer Imaging and Cellular Gene Therapy? Stem Cells: the international journal of cell differentiation and proliferation, 28(9), 1686-1702. [More Information]
  • Taft, R., Simons, C., Nahkuri, S., Oey, H., Korbie, D., Mercer, T., Holst, J., Ritchie, W., Wong, J., Rasko, J., et al (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17(8), 1030-1035. [More Information]
  • Broer, A., Vanslambrouck, J., Thavyogarajah, T., Holst, J., Bailey, C., Broer, S., Rasko, J. (2010). Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria. Biochemical Journal, 428(3), 397-407. [More Information]
  • Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010). Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature Biotechnology, 28(10), 1123-1128. [More Information]
  • Ritchie, W., Rajasekhar, M., Flamant, S., Rasko, J. (2009). Conserved expression patterns predict microRNA targets. PLoS Computational Biology, 5(9), e1000513 - 1-e1000513 - 8. [More Information]
  • Viiala, N., Larsen, S., Rasko, J. (2009). Gene therapy for hemophilia: clinical trials and technical tribulations. Seminars in Thrombosis and Hemostasis, 35(1), 81-92. [More Information]
  • Ritchie, W., Flamant, S., Rasko, J. (2009). mimiRNA: a microRNA expression profiler and classification resource designed to identify functional correlations between microRNAs and their targets. Bioinformatics, 26(2), 223-227. [More Information]
  • Ritchie, W., Flamant, S., Rasko, J. (2009). Predicting microRNA targets and functions: traps for the unwary. Nature Methods, 6(6), 397-398. [More Information]
  • Kowalczuk, S., Broer, A., Tietze, N., Vanslambrouck, J., Rasko, J., Broer, S. (2008). A protein complex in the brush-border membrane explains a Hartnup disorder allele. The F A S E B Journal, 22(8), 2880-2887. [More Information]
  • Baoutina, A., Alexander, I., Rasko, J., Emslie, K. (2008). Developing strategies for detection of gene doping. Journal of Gene Medicine, 10, 3-20. [More Information]
  • Azmanov, D., Kowalczuk, S., Rodgers, H., Auray-Blais, C., Giguere, R., Rasko, J., Broer, S., Cavanaugh, J. (2008). Further Evidence for Allellic Heterogeneity in Hartnup Disorder. Human Mutation, 29(10), 1217-1221. [More Information]
  • Bröer, S., Bailey, C., Kowalczuk, S., Ng, C., Vanslambrouck, J., Rodgers, H., Auray-Blais, C., Cavanaugh, J., Bröer, A., Rasko, J. (2008). Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. Journal of Clinical Investigation, 118(12), 3881-3892. [More Information]
  • Larsen, S., Chng, K., Battah, F., Martiniello-Wilks, R., Rasko, J. (2008). Improved Granulocyte Colony-Stimulating Factor Mobilization of Hemopoietic Progenitors Using Cytokine Combinations in Primates. Cloning and Stem Cells, 296, 2974-2980. [More Information]
  • Ritchie, W., Rasko, J., Marcucci, G., Radmacher, M., Bloomfield, C. (2008). MicroRNA in Acute Myeloid Leukemia. The New England Journal of Medicine, 359(6), 653-654. [More Information]
  • Power, C., Rasko, J. (2008). Whither prometheus' liver? Greek myth and the science of regeneration. Annals of Internal Medicine, 149(6), 421-426. [More Information]
  • Bailey, C., Rasko, J. (2007). Autofluorescent proteins for flow cytometry. Methods in Molecular Biology (Clifton N.J.), 411, 99-110. [More Information]
  • Mingozzi, F., Maus, M., Hui, D., Sabatino, D., Murphy, S., Rasko, J., Ragni, M., Manno, C., Sommer, J., Jiang, H., et al (2007). CD8+ T-cell responses to adeno-associated virus capsid in humans. Nature Medicine, 13(4), 419-422. [More Information]
  • Martiniello-Wilks, R., Rasko, J. (2007). Cell and gene therapy in Australia. Cytotherapy, 9(3), 209-221. [More Information]
  • Hayward, M., Potgens, A., Drewlo, S., Kaufmann, P., Rasko, J. (2007). Distribution of human endogenous retrovirus type W receptor in normal human villous placenta. Pathology, 39(4), 406-412. [More Information]
  • Iyengar, L., Wang, Q., Rasko, J., McAvoy, J., Lovicu, F. (2007). Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate. Differentiation: ontogeny, neoplasia and differentiation therapy, 75(7), 662-668. [More Information]
  • Levesque, J., Winkler, I., Larsen, S., Rasko, J. (2007). Mobilization of bone marrow-derived progenitors. Handbook of experimental pharmacology, 180, 3-36. [More Information]
  • Azmanov, D., Rodgers, H., Auray-Blais, C., Giguere, R., Bailey, C., Broer, S., Rasko, J., Cavanaugh, J. (2007). Persistence of the common Hartnup disease D173N allele in populations of European origin. Annals of Human Genetics, 71(6), 755-761. [More Information]
  • Baoutina, A., Alexander, I., Rasko, J., Emslie, K. (2007). Potential use of gene transfer in athletic performance enhancement. Molecular Therapy, 15(10), 1751-1766. [More Information]
  • Kovacic, J., Macdonald, P., Freund, J., Rasko, J., Allan, R., Fernandes, V., Ma, D., Moore, J., Graham, R. (2007). Profound thrombocytopenia related to G-CSF. American Journal Of Hematology, 82(3), 229-230. [More Information]
  • Horan, K., Watanabe, K., Kong, A., Bailey, C., Rasko, J., Sasaki, T., Mitchell, C. (2007). Regulation of FcgammaR-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3-mediated phagocytosis by differential recruitment of these 5-phosphatases to the phagocytic cup. Blood, 110(13), 4480-4491. [More Information]
  • Iyengar, L., Patkunanathan, B., Lynch, O., McAvoy, J., Rasko, J., Lovicu, F. (2006). Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling. Experimental Eye Research, 83(3), 667-678. [More Information]
  • Rasko, J. (2006). Bill to ban reproduction of inmates with cancer proposed in New South Wales. Medical Journal of Australia, 185(10), 575-576. [More Information]
  • Larsen, S., Chng, K., Battah, F., Armstrong, M., Hayward, M., Leung, L., Thomson, S., Hennessy, A., Rasko, J. (2006). Cytokine-induced in vivo expansion and mobilization of marrow mesenchymal stem cells in nonhuman primates. 12(2, Supplement 1), 107-107.
  • Larsen, S., Kingham, J., Hayward, M., Rasko, J. (2006). Damage to incisors after nonmyeloablative total body irradiation may complicate NOD/SCID models of hemopoietic stem cell transplantation. Comparative Medicine: animal models in biomedical research, 56(3), 209-214. [More Information]
  • McClorey, G., Fall, A., Moulton, H., Iversen, P., Rasko, J., Ryan, M., Fletcher, S., Wilton, S. (2006). Induced dystrophin exon skipping in human muscle explants. Neuromuscular Disorders, 16, 583-590.
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Bailey, C., Rasko, J., Allen, D., Semsarian, C. (2006). Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 41(4), 623-632. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Rasko, J., Bailey, C., Allen, D., Semsarian, C. (2006). Mouse cardiac troponin I model of hypertrophic cardiomyopathy: Phenotype associated with abnormal calcium handling. Journal of Molecular and Cellular Cardiology, 41(4), 747 (abstract 41)-747.
  • Kong, A., Horan, K., Sriratana, A., Bailey, C., Collyer, L., Nandurkar, H., Shisheva, A., Layton, M., Rasko, J., Rowe, T., et al (2006). Phosphatidylinositol 3-phosphate PtdIns(3)P is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: Endogenous PtdIns(3)P can promote GLUT4 translocation to the plasma membrane. Molecular and Cellular Biology, 26(16), 6065-6081.
  • Chng, K., Larsen, S., Zhou, S., Wright, J., Martiniello-Wilks, R., Rasko, J. (2006). Specific adeno-associated virus serotypes facilitate efficient gene transfer into human and non-human primate mesenchymal stromal cells. Journal of Gene Medicine, 9(1), 22-32. [More Information]
  • Manno, C., Pierce, G., Arruda, V., Glader, B., Ragni, M., Rasko, J., Ozelo, M., Hoots, K., Blatt, P., Konkle, B., et al (2006). Successful transduction of liver in hemophilia by AAV-factor IX and limitations imposed by the host immune response. Nature Medicine, 12(3), 342-347.
  • Holst, J., Rasko, J. (2006). The Use of Retroviral Vectors for Gene Transfer into Hematopoietic Stem Cells. Methods in Enzymology, 420, 82-100. [More Information]
  • Böhmer, C., Bröer, A., Munzinger, M., Kowalczuk, S., Rasko, J., Lang, F., Bröer, S. (2005). Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochemical Journal, 389(Part 3), 745-751. [More Information]
  • Orange, S., Rasko, J., Thompson, J., Vaughan, J., Olive, E., Pedler, M., Horvath, J., Hennessy, A. (2005). Interleukin-10 regulates arterial pressure in early primate pregnancy. Cytokine, 29(4), 176-185. [More Information]
  • Larsen, S., Rasko, J. (2005). Lymphoproliferative disorders: prospects for gene therapy. Pathology, 37(6), 523-533. [More Information]
  • Bröer, S., Cavanaugh, J., Rasko, J. (2005). Neutral amino acid transport in epithelial cells and its malfunction in Hartnup disorder. Biochemical Society Transactions, 33(Part 1), 233-236. [More Information]
  • Lu, D., Read, R., Humphreys, D., Battah, F., Martin, D., Rasko, J. (2005). PCR-based expression analysis and identification of microRNAs. Journal of RNAi and Gene Silencing, 1(1), 44-49. [More Information]
  • Green, B., Lee, C., Rasko, J. (2004). Biodistribution Of The Rd114/Mammalian Type D Retrovirus Receptor, Rdr. Journal of Gene Medicine, 6(3), 249-259. [More Information]
  • Zhang, R., Burke, L., Rasko, J., Lobanenkov, V., Renkawitz, R. (2004). Dynamic Association Of The Mammalian Insulator Protein Ctcf With Centrosomes And The Midbody. Experimental Cell Research: emphasizing molecular approaches to cell biology, 294(1), 86-93.
  • Seow, F., Broer, S., Broer, A., Bailey, C., Potter, S., Cavanaugh, J., Rasko, J. (2004). Hartnup Disorder Is Caused By Mutations In The Gene Encoding The Neutral Amino Acid Transporter Slc6A19. Nature Genetics, 36(9), 1003-1007.
  • Broer, A., Klingel, K., Kowalczuk, S., Rasko, J., Cavanaugh, J., Broer, S. (2004). Molecular Cloning Of Mouse Amino Acid Transport System B0, A Neutral Amino Acid Transporter Related To Hartnup Disorder. Journal of Biological Chemistry, 279(23), 24467-24476.
  • Rasko, J., Popp, F., Schlitt, H., Dahlke, M., Larsen, S. (2004). Stem Cell Therapy Of The Liver--Fusion Or Fiction? Liver Transplantation, 10(4), 471-479. [More Information]
  • Mithieux, S., Rasko, J., Weiss, A. (2004). Synthetic Elastin Hydrogels Derived From Massive Elastic Assemblies Of Self-Organized Human Protein Monomers. Biomaterials, 25(20), 4921-4927. [More Information]
  • Rasko, J., Schlitt, H., Dahlke, M., Larsen, S. (2004). The Biology Of Cd45 And Its Use As A Therapeutic Target. Leukemia and lymphoma, 45(2), 229-236.
  • Dolnikov, A., Shen, S., Millington, M., Passioura, T., Pedler, M., Rasko, J., Symonds, G. (2003). A sensitive dual-flurorescence reporter system enables positive selection of ras suppressors by suppression of ras-induced apoptosis. Cancer Gene Therapy, 10(10), 745-754.
  • Preis, J., Downes, M., Oates, N., Rasko, J., Whitelaw, E. (2003). Sensitive flow cytometric analysis reveals a novel type of parent-of-origin effect in the mouse genome. Current Biology, 13(11), 955-959.
  • Loukinov, D., Pugacheva, E., Vatolin, S., Pack, S., Moon, H., Chernukhin, I., Mannan, P., Larsson, E., Kanduri, C., Vostrov, A., Rasko, J., et al (2002). BORIS, a novel male germ line specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 99(10), 6806-6811.
  • Kiem, H., Rasko, J., Morris, J., Peterson, L., Kurre, P., Andrews, R. (2002). Ex vivo selection for oncoretrovirally transduced green fluorescent protein-expressing CD34-enriched cells increases short-term engraftment of transduced cells in baboons. Human Gene Therapy, 13(8), 891-899.
  • Potter, S., Lu, A., Wilcken, B., Green, A., Rasko, J. (2002). Hartnup disorder: Polymorphisms identified in the neutral amino acid transporter SLC1A5. Journal of Inherited Metabolic Disease (JIMD), 25(6), 437-448.
  • Green, B., Rasko, J. (2002). Rapid screening for high-titer retroviral packaging cell lines using an in situ fluorescence assay. Human Gene Therapy, 13(9), 1005-1013.
  • Rasko, J., Klenova,, E., Leon,, J., Filippova, G., Loukinov, D., Vatolin, S., Roblinson, A., Hu,, Y., Ulmer, J., Ward,, M., et al (2001). Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF1. Cancer Research, 61, 6002-6007.
  • Rasko, J., Goerner, M., Horn, P., Peterson, L., Kurre, P., Storb, R., Kiem, H. (2001). Sustained multilineage gene persistence and expression in dogs transplanted with CD34+ marrow cells transduced by RD114-pseudotype oncoretrovirus vectors. Blood, 98, 2065-2070.
  • Adams, D., Van der Weydon, L., Morris, B., Rasko, J., Mayeda,, A., Stamm, S. (2001). ZNF265--a novel spliceosomal protein able to induce alternative splicing. The Journal of Cell Biology, 154, 25-32.

Conferences

  • Day, M., Bailey, C., Rasko, J., Johnson, M., Cook, D. (2005). Maintenance of potassium channel activity prevents cell division in the mouse preimplantation embryo. The Society for the Study of Reproduction 38th Annual Meeting (SSR 2005), Kansas, USA: Allen Press Inc.
  • Gamvrellis, A., Marangolo, M., Bartlett, A., Sartor, M., Bailey, C., Rasko, J., Gottlieb, D. (2005). The use of adenoviral gene transfer to augment the immune response to human myeloid leukaemic cells. 35th Annual Scientific Meeting of the Australasian Society for Immunology 2005, Denmark: Blackwell Munksgaard.

2014

  • Lim, S., Becker, T., Chua, W., Caixeiro, N., Ng, W., Kienzle, N., Tognela, A., Lumba, S., Rasko, J., de Souza, P., et al (2014). Circulating Tumour Cells and Circulating Free Nucleic Acid as Prognostic and Predictive Biomarkers in Colorectal Cancer. Cancer Letters, 346, 24-33. [More Information]
  • Marshall, A., Bailey, C., Rasko, J. (2014). CTCF and BORIS in genome regulation and cancer. Current Opinion in Genetics & Development, 24C, 8-15. [More Information]

2013

  • Ritchie, W., Rasko, J., Flamant, S. (2013). MicroRNA Target Prediction and Validation. In Ulf Schmitz, Olaf Wolkenhauer, Julio Vera (Eds.), MicroRNA Cancer Regulation: Advanced Concepts, Bioinformatics and Systems Biology Tools, (pp. 39-53). Dordrecht: Springer.
  • Gordon, J., Wong, J., Rasko, J. (2013). MicroRNAs in myeloid malignancies. British Journal of Haematology, 162(2), 162-176. [More Information]
  • Gao, D., Middleton, R., Rasko, J., Ritchie, W. (2013). miREval 2.0: a web tool for simple microRNA prediction in genome sequences. Bioinformatics, 29(24), 3225-3226. [More Information]
  • Levesque, J., Winkler, I., Rasko, J. (2013). Nichotherapy for stem cells: There goes the neighborhood. BioEssays, 35(3), 183-190. [More Information]
  • Larkin, T., Pages, G., Chapman, B., Rasko, J., Kuchel, P. (2013). NMR q-space analysis of canonical shapes of human erythrocytes: stomatocytes, discocytes, spherocytes and echinocytes. European Biophysics Journal, 42(1), 3-16. [More Information]
  • Wong, J., Ritchie, W., Ebner, O., Selbach, M., Wong, J., Huang, Y., Gao, D., Pinello, N., Gonzalez, M., Baidya, K., Thoeng, A., Khoo, T., Bailey, C., Holst, J., Rasko, J. (2013). Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation. Cell, 154(3), 583-595. [More Information]
  • Khoo, T., Xiros, N., Guan, F., Orellana, D., Holst, J., Joshua, D., Rasko, J. (2013). Performance evaluation of the Abbott CELL-DYN Emerald for use as a bench-top analyzer in a research setting. International Journal of Laboratory Hematology, 35(4), 447-456. [More Information]
  • Wang, K., Tiffen, J., Bailey, C., Lehman, M., Ritchie, W., Fazli, L., Metierre, C., Feng, Y., Li, E., Gleave, M., Rasko, J., Holst, J., et al (2013). Targeting Amino Acid Transport in Metastatic Castration-Resistant Prostate Cancer: Effects on Cell Cycle, Cell Growth, and Tumor Development. National Cancer Institute. Journal, 105(19), 1463-1473. [More Information]
  • Tiffen, J., Bailey, C., Marshall, A., Metierre, C., Feng, Y., Wang, K., Watson, S., Holst, J., Rasko, J. (2013). The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. International Journal of Cancer, 133(7), 1603-1614. [More Information]

2012

  • Ritchie, W., Gao, D., Rasko, J. (2012). Defining and providing robust controls for microRNA prediction. Bioinformatics, 28(8), 1058-1061. [More Information]
  • Ritchie, W., Rasko, J. (2012). Integrated miRNA expression analysis and target prediction. In Jian-Bing Fan (Eds.), Methods in Molecular Biology: Next-Generation MicroRNA Expression Profiling Technology: Methods and Protocols, (pp. 289-293). New York, United States: Springer.

2011

  • Wang, Q., Bailey, C., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M., Hendy, S., Buchanan, G., Nelson, C., Rasko, J., Holst, J. (2011). Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression. Cancer Research, 71(24), 7525-7536. [More Information]
  • Macpherson, J., Rasko, J. (2011). Cellular therapy in the Asia-Pacific region. A guide for the future pathologist. Pathology, 43(6), 616-626. [More Information]
  • Rasko, J. (2011). Future Path: frontiers of molecular and cellular pathology. Pathology, 43(6), 523-524. [More Information]
  • Both, G., Alexander, I., Fletcher, S., Nicolson, T., Rasko, J., Wilton, S., Symonds, G. (2011). Gene therapy: therapeutic applications and relevance to pathology. Pathology, 43(6), 642-656. [More Information]
  • Herbert, K., Levesque, J., Mills, A., Gottlieb, D., Cooney, J., Szer, J., Rasko, J., To, L. (2011). How we mobilize haemopoietic stem cells. Internal Medicine Journal, 41(8), 588-594. [More Information]
  • Balamatsias, D., Kong, A., Waters, J., Sriratana, A., Gurung, R., Bailey, C., Rasko, J., Tiganis, T., Macaulay, S., Mitchell, C. (2011). Identification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytes. Journal of Biological Chemistry, 286(50), 43229-43240. [More Information]
  • Broer, A., Juelich, T., Vanslambrouck, J., Tietze, N., Solomon, P., Holst, J., Bailey, C., Rasko, J., Broer, S. (2011). Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. Journal of Biological Chemistry, 286(30), 26638-26651. [More Information]
  • Bailey, C., Ryan, R., Theong, A., Ng, C., King, K., Vanslambrouck, J., Auray-Blais, C., Vandenberg, R., Bröer, S., Rasko, J. (2011). Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. Journal of Clinical Investigation, 121(1), 446-453. [More Information]
  • To, L., Levesque, J., Herbert, K., Winkler, I., Bendall, L., Hiwase, D., Antonenas, V., Rice, A., Gottlieb, D., Mills, A., Rasko, J., et al (2011). Mobilisation strategies for normal and malignant cells. Pathology, 43(6), 547-565. [More Information]
  • Power, C., Rasko, J. (2011). Promises and challenges of stem cell research for regenerative medicine. Annals of Internal Medicine, 155(10), 706-713. [More Information]
  • Choi, P., Rasko, J. (2011). The challenge of investigating thrombocytopenia. Medicine Today, 12(2), 26-35.
  • Holst, J., Rasko, J. (2011). The use of retroviral vectors for gene transfer into hematopoietic stem cells. Methods in Enzymology, 420, 82-100. [More Information]
  • Power, C., Rasko, J. (2011). Will Cell Reprogramming Resolve the Embryonic Stem Cell Controversy? A Narrative Review. Annals of Internal Medicine, 155(2), 114-121. [More Information]

2010

  • Rasko, J. (2010). A gene therapy renaissance? Journal of Gastroenterology and Hepatology, 25(5), 848-850. [More Information]
  • Khalafallah, A., Dennis, A., Bates, J., Bates, G., Smith, L., Ball, M., Seaton, D., Brain, T., Rasko, J. (2010). A prospective randomized, controlled trial of intravenous versus oral iron for moderate iron deficiency anaemia of pregnancy. Journal of Internal Medicine, 268(3), 286-295. [More Information]
  • Sen, S., Merchan, J., Dean, J., Li, M., Gavin, M., Silver, M., Tkebuchava, T., Yoon, Y., Rasko, J., Aikawa, R. (2010). Autologous transplantation of endothelial progenitor cells genetically modified by adeno-associated viral vector delivering insulin-like growth factor-1 gene after myocardial infarction. Human Gene Therapy, 21(10), 1327-1334. [More Information]
  • Gunter, K., Caplan, A., Mason, C., Salzman, R., Janssen, W., Nichols, K., Bouzas, L., Lanza, F., Levine, B., Rasko, J., et al (2010). Cell therapy medical tourism: Time for action. Cytotherapy, 12(8), 965-968. [More Information]
  • Einecke, G., Kayser, D., Vanslambrouck, J., Sis, B., Reeve, J., Mengel, M., Famulski, K., Bailey, C., Rasko, J., Halloran, P. (2010). Loss of solute carriers in T cell-mediated rejection in mouse and human kidneys: an active epithelial injury-repair response. American Journal Of Transplantation, 10(10), 2241-2251. [More Information]
  • Tiffen, J., Bailey, C., Ng, C., Rasko, J., Holst, J. (2010). Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo. Molecular Cancer, 9, 299-1-299-8. [More Information]
  • Flamant, S., Ritchie, W., Guilhot, J., Holst, J., Bonnet, M., Chomel, J., Guilhot, F., Turhan, A., Rasko, J. (2010). Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia. Haematologica: the hematology journal, 95(8), 1325-1333. [More Information]
  • Tang, C., Russell, P., Martiniello-Wilks, R., Rasko, J., Khatri, A. (2010). Nanoparticles and Cellular Carriers - Allies in Cancer Imaging and Cellular Gene Therapy? Stem Cells: the international journal of cell differentiation and proliferation, 28(9), 1686-1702. [More Information]
  • Taft, R., Simons, C., Nahkuri, S., Oey, H., Korbie, D., Mercer, T., Holst, J., Ritchie, W., Wong, J., Rasko, J., et al (2010). Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans. Nature Structural and Molecular Biology, 17(8), 1030-1035. [More Information]
  • Broer, A., Vanslambrouck, J., Thavyogarajah, T., Holst, J., Bailey, C., Broer, S., Rasko, J. (2010). Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria. Biochemical Journal, 428(3), 397-407. [More Information]
  • Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010). Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature Biotechnology, 28(10), 1123-1128. [More Information]

2009

  • Ritchie, W., Rajasekhar, M., Flamant, S., Rasko, J. (2009). Conserved expression patterns predict microRNA targets. PLoS Computational Biology, 5(9), e1000513 - 1-e1000513 - 8. [More Information]
  • Viiala, N., Larsen, S., Rasko, J. (2009). Gene therapy for hemophilia: clinical trials and technical tribulations. Seminars in Thrombosis and Hemostasis, 35(1), 81-92. [More Information]
  • Ritchie, W., Flamant, S., Rasko, J. (2009). mimiRNA: a microRNA expression profiler and classification resource designed to identify functional correlations between microRNAs and their targets. Bioinformatics, 26(2), 223-227. [More Information]
  • Ritchie, W., Flamant, S., Rasko, J. (2009). Predicting microRNA targets and functions: traps for the unwary. Nature Methods, 6(6), 397-398. [More Information]

2008

  • Kowalczuk, S., Broer, A., Tietze, N., Vanslambrouck, J., Rasko, J., Broer, S. (2008). A protein complex in the brush-border membrane explains a Hartnup disorder allele. The F A S E B Journal, 22(8), 2880-2887. [More Information]
  • Baoutina, A., Alexander, I., Rasko, J., Emslie, K. (2008). Developing strategies for detection of gene doping. Journal of Gene Medicine, 10, 3-20. [More Information]
  • Azmanov, D., Kowalczuk, S., Rodgers, H., Auray-Blais, C., Giguere, R., Rasko, J., Broer, S., Cavanaugh, J. (2008). Further Evidence for Allellic Heterogeneity in Hartnup Disorder. Human Mutation, 29(10), 1217-1221. [More Information]
  • Bröer, S., Bailey, C., Kowalczuk, S., Ng, C., Vanslambrouck, J., Rodgers, H., Auray-Blais, C., Cavanaugh, J., Bröer, A., Rasko, J. (2008). Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. Journal of Clinical Investigation, 118(12), 3881-3892. [More Information]
  • Larsen, S., Chng, K., Battah, F., Martiniello-Wilks, R., Rasko, J. (2008). Improved Granulocyte Colony-Stimulating Factor Mobilization of Hemopoietic Progenitors Using Cytokine Combinations in Primates. Cloning and Stem Cells, 296, 2974-2980. [More Information]
  • Ritchie, W., Rasko, J., Marcucci, G., Radmacher, M., Bloomfield, C. (2008). MicroRNA in Acute Myeloid Leukemia. The New England Journal of Medicine, 359(6), 653-654. [More Information]
  • Power, C., Rasko, J. (2008). Whither prometheus' liver? Greek myth and the science of regeneration. Annals of Internal Medicine, 149(6), 421-426. [More Information]

2007

  • Bailey, C., Rasko, J. (2007). Autofluorescent proteins for flow cytometry. Methods in Molecular Biology (Clifton N.J.), 411, 99-110. [More Information]
  • Mingozzi, F., Maus, M., Hui, D., Sabatino, D., Murphy, S., Rasko, J., Ragni, M., Manno, C., Sommer, J., Jiang, H., et al (2007). CD8+ T-cell responses to adeno-associated virus capsid in humans. Nature Medicine, 13(4), 419-422. [More Information]
  • Martiniello-Wilks, R., Rasko, J. (2007). Cell and gene therapy in Australia. Cytotherapy, 9(3), 209-221. [More Information]
  • Hayward, M., Potgens, A., Drewlo, S., Kaufmann, P., Rasko, J. (2007). Distribution of human endogenous retrovirus type W receptor in normal human villous placenta. Pathology, 39(4), 406-412. [More Information]
  • Iyengar, L., Wang, Q., Rasko, J., McAvoy, J., Lovicu, F. (2007). Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate. Differentiation: ontogeny, neoplasia and differentiation therapy, 75(7), 662-668. [More Information]
  • Levesque, J., Winkler, I., Larsen, S., Rasko, J. (2007). Mobilization of bone marrow-derived progenitors. Handbook of experimental pharmacology, 180, 3-36. [More Information]
  • Azmanov, D., Rodgers, H., Auray-Blais, C., Giguere, R., Bailey, C., Broer, S., Rasko, J., Cavanaugh, J. (2007). Persistence of the common Hartnup disease D173N allele in populations of European origin. Annals of Human Genetics, 71(6), 755-761. [More Information]
  • Baoutina, A., Alexander, I., Rasko, J., Emslie, K. (2007). Potential use of gene transfer in athletic performance enhancement. Molecular Therapy, 15(10), 1751-1766. [More Information]
  • Kovacic, J., Macdonald, P., Freund, J., Rasko, J., Allan, R., Fernandes, V., Ma, D., Moore, J., Graham, R. (2007). Profound thrombocytopenia related to G-CSF. American Journal Of Hematology, 82(3), 229-230. [More Information]
  • Horan, K., Watanabe, K., Kong, A., Bailey, C., Rasko, J., Sasaki, T., Mitchell, C. (2007). Regulation of FcgammaR-stimulated phagocytosis by the 72-kDa inositol polyphosphate 5-phosphatase: SHIP1, but not the 72-kDa 5-phosphatase, regulates complement receptor 3-mediated phagocytosis by differential recruitment of these 5-phosphatases to the phagocytic cup. Blood, 110(13), 4480-4491. [More Information]

2006

  • Iyengar, L., Patkunanathan, B., Lynch, O., McAvoy, J., Rasko, J., Lovicu, F. (2006). Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling. Experimental Eye Research, 83(3), 667-678. [More Information]
  • Rasko, J. (2006). Bill to ban reproduction of inmates with cancer proposed in New South Wales. Medical Journal of Australia, 185(10), 575-576. [More Information]
  • Larsen, S., Chng, K., Battah, F., Armstrong, M., Hayward, M., Leung, L., Thomson, S., Hennessy, A., Rasko, J. (2006). Cytokine-induced in vivo expansion and mobilization of marrow mesenchymal stem cells in nonhuman primates. 12(2, Supplement 1), 107-107.
  • Larsen, S., Kingham, J., Hayward, M., Rasko, J. (2006). Damage to incisors after nonmyeloablative total body irradiation may complicate NOD/SCID models of hemopoietic stem cell transplantation. Comparative Medicine: animal models in biomedical research, 56(3), 209-214. [More Information]
  • McClorey, G., Fall, A., Moulton, H., Iversen, P., Rasko, J., Ryan, M., Fletcher, S., Wilton, S. (2006). Induced dystrophin exon skipping in human muscle explants. Neuromuscular Disorders, 16, 583-590.
  • O'Sullivan, G., Ankeny, R., Rasko, J. (2006). Is Inheritable Genetic Modification the New Dividing Line?? In John E. J. Rasko; Gabrielle M. O'Sullivan; Rachel A. Ankeny (Eds.), The Ethics of Inheritable Genetic Modification: A Dividing Line?, (pp. 1-15). Cambridge, UK: Cambridge University Press.
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Bailey, C., Rasko, J., Allen, D., Semsarian, C. (2006). Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 41(4), 623-632. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Rasko, J., Bailey, C., Allen, D., Semsarian, C. (2006). Mouse cardiac troponin I model of hypertrophic cardiomyopathy: Phenotype associated with abnormal calcium handling. Journal of Molecular and Cellular Cardiology, 41(4), 747 (abstract 41)-747.
  • Kong, A., Horan, K., Sriratana, A., Bailey, C., Collyer, L., Nandurkar, H., Shisheva, A., Layton, M., Rasko, J., Rowe, T., et al (2006). Phosphatidylinositol 3-phosphate PtdIns(3)P is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: Endogenous PtdIns(3)P can promote GLUT4 translocation to the plasma membrane. Molecular and Cellular Biology, 26(16), 6065-6081.
  • Chng, K., Larsen, S., Zhou, S., Wright, J., Martiniello-Wilks, R., Rasko, J. (2006). Specific adeno-associated virus serotypes facilitate efficient gene transfer into human and non-human primate mesenchymal stromal cells. Journal of Gene Medicine, 9(1), 22-32. [More Information]
  • Manno, C., Pierce, G., Arruda, V., Glader, B., Ragni, M., Rasko, J., Ozelo, M., Hoots, K., Blatt, P., Konkle, B., et al (2006). Successful transduction of liver in hemophilia by AAV-factor IX and limitations imposed by the host immune response. Nature Medicine, 12(3), 342-347.
  • Rasko, J., Jolly, D. (2006). The science of inheritable genetic modification. In John E. J. Rasko; Gabrielle M. O'Sullivan; Rachel A. Ankeny (Eds.), The Ethics of Inheritable Genetic Modification: A Dividing Line?, (pp. 17-33). Cambridge, UK: Cambridge University Press.
  • Holst, J., Rasko, J. (2006). The Use of Retroviral Vectors for Gene Transfer into Hematopoietic Stem Cells. Methods in Enzymology, 420, 82-100. [More Information]

2005

  • Böhmer, C., Bröer, A., Munzinger, M., Kowalczuk, S., Rasko, J., Lang, F., Bröer, S. (2005). Characterization of mouse amino acid transporter B0AT1 (slc6a19). Biochemical Journal, 389(Part 3), 745-751. [More Information]
  • Orange, S., Rasko, J., Thompson, J., Vaughan, J., Olive, E., Pedler, M., Horvath, J., Hennessy, A. (2005). Interleukin-10 regulates arterial pressure in early primate pregnancy. Cytokine, 29(4), 176-185. [More Information]
  • Larsen, S., Rasko, J. (2005). Lymphoproliferative disorders: prospects for gene therapy. Pathology, 37(6), 523-533. [More Information]
  • Day, M., Bailey, C., Rasko, J., Johnson, M., Cook, D. (2005). Maintenance of potassium channel activity prevents cell division in the mouse preimplantation embryo. The Society for the Study of Reproduction 38th Annual Meeting (SSR 2005), Kansas, USA: Allen Press Inc.
  • Bröer, S., Cavanaugh, J., Rasko, J. (2005). Neutral amino acid transport in epithelial cells and its malfunction in Hartnup disorder. Biochemical Society Transactions, 33(Part 1), 233-236. [More Information]
  • Lu, D., Read, R., Humphreys, D., Battah, F., Martin, D., Rasko, J. (2005). PCR-based expression analysis and identification of microRNAs. Journal of RNAi and Gene Silencing, 1(1), 44-49. [More Information]
  • Gamvrellis, A., Marangolo, M., Bartlett, A., Sartor, M., Bailey, C., Rasko, J., Gottlieb, D. (2005). The use of adenoviral gene transfer to augment the immune response to human myeloid leukaemic cells. 35th Annual Scientific Meeting of the Australasian Society for Immunology 2005, Denmark: Blackwell Munksgaard.

2004

  • Green, B., Lee, C., Rasko, J. (2004). Biodistribution Of The Rd114/Mammalian Type D Retrovirus Receptor, Rdr. Journal of Gene Medicine, 6(3), 249-259. [More Information]
  • Zhang, R., Burke, L., Rasko, J., Lobanenkov, V., Renkawitz, R. (2004). Dynamic Association Of The Mammalian Insulator Protein Ctcf With Centrosomes And The Midbody. Experimental Cell Research: emphasizing molecular approaches to cell biology, 294(1), 86-93.
  • Seow, F., Broer, S., Broer, A., Bailey, C., Potter, S., Cavanaugh, J., Rasko, J. (2004). Hartnup Disorder Is Caused By Mutations In The Gene Encoding The Neutral Amino Acid Transporter Slc6A19. Nature Genetics, 36(9), 1003-1007.
  • Broer, A., Klingel, K., Kowalczuk, S., Rasko, J., Cavanaugh, J., Broer, S. (2004). Molecular Cloning Of Mouse Amino Acid Transport System B0, A Neutral Amino Acid Transporter Related To Hartnup Disorder. Journal of Biological Chemistry, 279(23), 24467-24476.
  • Rasko, J., Popp, F., Schlitt, H., Dahlke, M., Larsen, S. (2004). Stem Cell Therapy Of The Liver--Fusion Or Fiction? Liver Transplantation, 10(4), 471-479. [More Information]
  • Mithieux, S., Rasko, J., Weiss, A. (2004). Synthetic Elastin Hydrogels Derived From Massive Elastic Assemblies Of Self-Organized Human Protein Monomers. Biomaterials, 25(20), 4921-4927. [More Information]
  • Rasko, J., Schlitt, H., Dahlke, M., Larsen, S. (2004). The Biology Of Cd45 And Its Use As A Therapeutic Target. Leukemia and lymphoma, 45(2), 229-236.

2003

  • Dolnikov, A., Shen, S., Millington, M., Passioura, T., Pedler, M., Rasko, J., Symonds, G. (2003). A sensitive dual-flurorescence reporter system enables positive selection of ras suppressors by suppression of ras-induced apoptosis. Cancer Gene Therapy, 10(10), 745-754.
  • Preis, J., Downes, M., Oates, N., Rasko, J., Whitelaw, E. (2003). Sensitive flow cytometric analysis reveals a novel type of parent-of-origin effect in the mouse genome. Current Biology, 13(11), 955-959.

2002

  • Loukinov, D., Pugacheva, E., Vatolin, S., Pack, S., Moon, H., Chernukhin, I., Mannan, P., Larsson, E., Kanduri, C., Vostrov, A., Rasko, J., et al (2002). BORIS, a novel male germ line specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 99(10), 6806-6811.
  • Kiem, H., Rasko, J., Morris, J., Peterson, L., Kurre, P., Andrews, R. (2002). Ex vivo selection for oncoretrovirally transduced green fluorescent protein-expressing CD34-enriched cells increases short-term engraftment of transduced cells in baboons. Human Gene Therapy, 13(8), 891-899.
  • Potter, S., Lu, A., Wilcken, B., Green, A., Rasko, J. (2002). Hartnup disorder: Polymorphisms identified in the neutral amino acid transporter SLC1A5. Journal of Inherited Metabolic Disease (JIMD), 25(6), 437-448.
  • Green, B., Rasko, J. (2002). Rapid screening for high-titer retroviral packaging cell lines using an in situ fluorescence assay. Human Gene Therapy, 13(9), 1005-1013.

2001

  • Rasko, J., Klenova,, E., Leon,, J., Filippova, G., Loukinov, D., Vatolin, S., Roblinson, A., Hu,, Y., Ulmer, J., Ward,, M., et al (2001). Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF1. Cancer Research, 61, 6002-6007.
  • Rasko, J., Goerner, M., Horn, P., Peterson, L., Kurre, P., Storb, R., Kiem, H. (2001). Sustained multilineage gene persistence and expression in dogs transplanted with CD34+ marrow cells transduced by RD114-pseudotype oncoretrovirus vectors. Blood, 98, 2065-2070.
  • Adams, D., Van der Weydon, L., Morris, B., Rasko, J., Mayeda,, A., Stamm, S. (2001). ZNF265--a novel spliceosomal protein able to induce alternative splicing. The Journal of Cell Biology, 154, 25-32.

2000

  • Rasko, J., Celermajer, D. (2000). Gene therapy for vascular diseases. In RT Dean, D Kelly (Eds.), Atherosclerosis: Gene Expression, Cell Interactions, and Oxidation, (pp. 112-136). Oxford: Oxford University Press.

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