student profile: Dr John Turchini


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Thesis work

Thesis title: Digital technology in anatomical pathology and impacts in medical education

Supervisors: Kirsty FOSTER , Anthony GILL , Michael BUCKLAND

Thesis abstract:

Anatomical pathology is a medical speciality that is in low demand amongst medical graduates in Australia. Contributing factors to this issue include inadequate exposure to the specialty and poor educational delivery during medical school. With the advent of digital technology both in pathology and in learning, the possibility of increasing medical student exposure to pathology has never been more immense. Newer technologies that can be employed by educators include three dimensional (3D) photogrammetry and whole slide scanning. These technologies can replace the overcrowded and obsolete microscope rooms and museums and allow students to have a digital one on one guide through each specimen and slide. This technology can connect the clinical history with the pathology specimens and then tie together with learning objectives and the problem case of the week to bring a truly interactive experience which students can participate in at any time or place.

This thesis seeks to establish if transitioning to digital pathology education impacts on examination results in pathology and on attitudes of students towards pathology. This multicentre project will be acquiring 3D images of museum specimens, and routine surgical specimens as well as whole slide scanned images to digitise the pathology museum in both macroscopic and microscopic formats. I will be using exam results from three different cohorts of the medical program to examine for a significant difference in performance in the pathology spot test before and after introducing the digital museum. I will also examine student attitudes towards pathology using regular surveys. Additionally, I will be surveying existing pathologists and trainees regarding their pathology education in medical school, and looking for features that attracted them to the specialty. Lastly I will also survey existing pathologists regarding the ethics of photography in pathology and what pathologists find acceptable for ethical practice.

Selected publications

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Journals

  • Turchini, J., Cheung, V., Tischler, A., De Krijger, R., Gill, A. (2018). Pathology and genetics of phaeochromocytoma and paraganglioma. Histopathology, 72(1), 97-105. [More Information]
  • Turchini, J., Buckland, M., Gill, A., Battye, S. (2018). Three-Dimensional Pathology Specimen Modeling Using Structure-From-Motion" Photogrammetry: A Powerful New Tool for Surgical Pathology". Archives of Pathology & Laboratory Medicine, 142(11), 1415-1420. [More Information]
  • Cho, A., Hes, O., Turchini, J., Trpkov, K., Gill, A. (2017). Do significant TFE3 gene rearrangements occur in succinate dehydrogenase-deficient renal cell carcinoma? Borderline FISH results should be interpreted with caution. Modern Pathology, 30(10), 1507-1508. [More Information]
  • Pickett, J., Chou, A., Andrici, J., Clarkson, A., Sioson, L., Sheen, A., Reagh, J., Najdawi, F., Kim, Y., Riley, D., Gard, G., Hogg, R., Turchini, J., Gill, A., et al (2017). Inflammatory Myofibroblastic Tumors of the Female Genital Tract Are Under-recognized: A Low Threshold for ALK Immunohistochemistry Is Required. American Journal of Surgical Pathology, 41(10), 1433-1442. [More Information]
  • Najdawi, F., Crook, A., Maidens, J., McEvoy, C., Fellowes, A., Pickett, J., Ho, M., Nevell, D., Mcilroy, K., Sheen, A., Turchini, J., Hogg, R., Gard, G., Gill, A., et al (2017). Lessons learnt from implementation of a Lynch syndrome screening program for patients with gynaecological malignancy. Pathology, 49(5), 457-464. [More Information]
  • Reagh, J., Bullock, M., Andrici, J., Turchini, J., Sioson, L., Clarkson, A., Watson, N., Sheen, A., Lim, G., Delbridge, L., Sidhu, S., Sywak, M., Field, M., Learoyd, D., Robinson, B., Clifton-Bligh, R., Gill, A., et al (2017). NRASQ61R mutation-specific immunohistochemistry also identifies the HRASQ61R mutation in medullary thyroid cancer and may have a role in triaging genetic testing for MEN2. American Journal of Surgical Pathology, 41(1), 75-81. [More Information]
  • Turchini, J., Andrici, J., Sioson, L., Clarkson, A., Watson, N., Toon, C., Shepherd, P., Ng, D., Dixon-McIver, A., Oei, P., Gill, A. (2017). NRASQ61R Mutation-specific Immunohistochemistry is Highly Specific for Either NRASQ61R or KRASQ61R Mutation in Colorectal Carcinoma. Applied Immunohistochemistry and Molecular Morphology, 25(7), 475-480. [More Information]
  • Papathomas, T., Pucci, E., Giordano, T., Lu, H., Duregon, E., volante, M., Papotti, M., Lloyd, R., Tischler, A., Turchini, J., Gill, A., et al (2016). An International Ki67 Reproducibility Study in Adrenal Cortical Carcinoma. The American Journal of Surgical Pathology, 40(4), 569-576. [More Information]
  • Wang, J., Andrici, J., Sioson, L., Clarkson, A., Sheen, A., Farzin, M., Toon, C., Turchini, J., Gill, A. (2016). Loss of INI1 expression in colorectal carcinoma is associated with high tumor grade, poor survival, BRAFV600E mutation, and mismatch repair deficiency. Human Pathology, 55, 83-90. [More Information]

2018

  • Turchini, J., Cheung, V., Tischler, A., De Krijger, R., Gill, A. (2018). Pathology and genetics of phaeochromocytoma and paraganglioma. Histopathology, 72(1), 97-105. [More Information]
  • Turchini, J., Buckland, M., Gill, A., Battye, S. (2018). Three-Dimensional Pathology Specimen Modeling Using Structure-From-Motion" Photogrammetry: A Powerful New Tool for Surgical Pathology". Archives of Pathology & Laboratory Medicine, 142(11), 1415-1420. [More Information]

2017

  • Cho, A., Hes, O., Turchini, J., Trpkov, K., Gill, A. (2017). Do significant TFE3 gene rearrangements occur in succinate dehydrogenase-deficient renal cell carcinoma? Borderline FISH results should be interpreted with caution. Modern Pathology, 30(10), 1507-1508. [More Information]
  • Pickett, J., Chou, A., Andrici, J., Clarkson, A., Sioson, L., Sheen, A., Reagh, J., Najdawi, F., Kim, Y., Riley, D., Gard, G., Hogg, R., Turchini, J., Gill, A., et al (2017). Inflammatory Myofibroblastic Tumors of the Female Genital Tract Are Under-recognized: A Low Threshold for ALK Immunohistochemistry Is Required. American Journal of Surgical Pathology, 41(10), 1433-1442. [More Information]
  • Najdawi, F., Crook, A., Maidens, J., McEvoy, C., Fellowes, A., Pickett, J., Ho, M., Nevell, D., Mcilroy, K., Sheen, A., Turchini, J., Hogg, R., Gard, G., Gill, A., et al (2017). Lessons learnt from implementation of a Lynch syndrome screening program for patients with gynaecological malignancy. Pathology, 49(5), 457-464. [More Information]
  • Reagh, J., Bullock, M., Andrici, J., Turchini, J., Sioson, L., Clarkson, A., Watson, N., Sheen, A., Lim, G., Delbridge, L., Sidhu, S., Sywak, M., Field, M., Learoyd, D., Robinson, B., Clifton-Bligh, R., Gill, A., et al (2017). NRASQ61R mutation-specific immunohistochemistry also identifies the HRASQ61R mutation in medullary thyroid cancer and may have a role in triaging genetic testing for MEN2. American Journal of Surgical Pathology, 41(1), 75-81. [More Information]
  • Turchini, J., Andrici, J., Sioson, L., Clarkson, A., Watson, N., Toon, C., Shepherd, P., Ng, D., Dixon-McIver, A., Oei, P., Gill, A. (2017). NRASQ61R Mutation-specific Immunohistochemistry is Highly Specific for Either NRASQ61R or KRASQ61R Mutation in Colorectal Carcinoma. Applied Immunohistochemistry and Molecular Morphology, 25(7), 475-480. [More Information]

2016

  • Papathomas, T., Pucci, E., Giordano, T., Lu, H., Duregon, E., volante, M., Papotti, M., Lloyd, R., Tischler, A., Turchini, J., Gill, A., et al (2016). An International Ki67 Reproducibility Study in Adrenal Cortical Carcinoma. The American Journal of Surgical Pathology, 40(4), 569-576. [More Information]
  • Wang, J., Andrici, J., Sioson, L., Clarkson, A., Sheen, A., Farzin, M., Toon, C., Turchini, J., Gill, A. (2016). Loss of INI1 expression in colorectal carcinoma is associated with high tumor grade, poor survival, BRAFV600E mutation, and mismatch repair deficiency. Human Pathology, 55, 83-90. [More Information]

Note: This profile is for a student at the University of Sydney. Views presented here are not necessarily those of the University.