Professor Jonathan Iredell

MBBS, PhD, FRACP, FRCPA, FFScRCPA
Professor of Medicine and Microbiology (conj.), Westmead Clinical School
Director, Infectious Diseases, Westmead Hospital and Western Sydney Local Health District
Deputy Director, Microbiology, ICPMR, Pathology West
NHMRC Practitioner Research Fellow

Telephone +61 2 9845 6255

Website Critical Infection CRE

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Biographical details

Professor Jonathan (Jon) Iredell is an infectious diseases physician and clinical microbiologist specialising in critical infections and transmission of antibiotic resistance. He is the Director of the NHMRC Centre of Research Excellence (CRE) in Critical Infectious Diseases at the Westmead Millennium Institute for Medical Research, and President of the Australian Society for Microbiology. "The critically ill are the most vulnerable people in our health system”, says Professor Iredell. “Most ICU admissions are precipitated or complicated by infection, which is the commonest cause of preventable mortality. We aim to identify which patients admitted to ICUs are at highest risk, deliver this critical information early and to develop rapid diagnostic tests to assist intensive care specialists in making treatment decisions, with the objective of optimising infection management and control strategies, which benefits the patient and the hospital system”. He developed Australia’s first Short Course in Critical Infection, for clinicians who manage infection in critically ill patients. Professor Iredell has a strong interest in antimicrobial stewardship and works to inform policy on antibiotic use in the hospital environment. He has served on the Australian Commission on Safety and Quality in Health Care (ACSQHC) Multi Resistant Gram-negative Taskforce and on the Gene Technology Technical Advisory Committee of the Office of the Gene Technology Regulator. He has full professional membership of the Australia and New Zealand Intensive Care Society and is a Foundation Fellow of the Royal College of Pathologists of Australasia Faculty of Science.

Research interests

Professor Iredell conducts basic and clinical research, combining his clinical expertise in critical care and long-standing research in molecular genetics. He develops and coordinates nationwide clinical trials related to life-threatening infections. His research covers critical infections and microbial ecology, especially in relation to transmissible antimicrobial resistance in bacteria.

Recent and contemporary projects include the study of bacterial load in septic shock (the BLISS study) and on transmissible resistance genetics in organisms such as E coli and Klebsiella sp, commonly implicated in life-threatening septic shock. Studies on the geographic distribution (Australia and global) and temporal variation of the antibiotic resistance gene pool are also underway (with Australian data implicating limited diversity in the transmissible antibiotic resistance gene pool). The team will exploit these data to develop diagnostic tests (using human blood) for key antibiotic resistance markers in Enterobacteriaceae, at the point of presentation to hospital with severe sepsis. Additionally, his team seeks to better understand the associations between resistance genes conferring key phenotypes and their predominant means of spread, to help inform future surveillance and targeting of diagnostics.

Since antibiotic therapy is the cornerstone of managing critical infections, understanding the effects of antibiotics on the human microflora and on subsequent development of antibiotic resistance is crucial. Professor Iredell’s team is studying the impact of antibiotics on the microbial ecology of humans, and the correlations between antibiotics that cause greater disturbance of major bacteria in the microbiota and subsequent colonisation by antibiotic-resistant bacteria. New studies are investigating whether selective digestive tract decontamination with different types of antibiotics is associated with differing levels of disturbance of gut microflora and of antibiotic resistance, and the impact of such strategies on ICU outcomes.

Additional work includes specific manipulation of plasmid systems to reverse engineer antibiotic susceptibility in bacteria in vivo, and future work will involve targeting specific bacterial clones with bacteriophage therapy and building a (globally-relevant) bank of probiotic plasmids that can protect the gut microflora.

Current projects

Graduate student places are limited at present but research training opportunities exist and new ideas are welcomed in the following areas:

1. Epidemiology of antibiotic resistance and antibiotic resistance plasmids in key members of the Enterobacteriaceae

2. Determinants of host range in plasmids of the Enterobacteriaceae, particularly with regard to the distribution and genetics of conjugation and addiction systems.

3. The influence of selection pressure on the microflora

4. Development of rapid typing systems and rapid diagnostics, particularly in the area of transmissible antibiotic resistance in bacterial agents of severe sepsis and shock

5. Clinical and biological predictors of outcome in sepsis and septic shock

6. Novel/ alternative approaches to bacterial therapy, including bacteriophage therapy

Selected grants

2015

  • Curing antibiotic resistance: probiotic plasmids and microbial husbandry in the Enterobacteriaceae; Iredell J, Kamruzzaman M, Partridge S, Paulsen I; National Health and Medical Research Council (NHMRC)/Project Grants.

2014

  • Black Death genomics and the evolution of pathogen virulence; Holmes E, Poinar H, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.

2013

  • Ecological effects of antibiotics; Iredell J, Paulsen I, Partridge S, Seppelt I, Holmes A; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Rapid prediction of antibiotic resistance in the Enterobacteriaceae: making use of restricted diversity in mobile resistance gene pools; Iredell J, Partridge S; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Sydney Infectious Diseases and Biosecurity Network (SIBRN); Dhand N, Sorrell T, Bennett B, Booy R, Crawford J, Dwyer D, Gilbert G, Giles F, Holmes A, Hossain L, Iredell J, Jones C, Kesson A, Kerridge I, Marais B, Simpson S, Sintchenko V, Ward M, Werder O, Britton W, Hunter C, Kamradt-Scott A, Mor S, Salkeld G, Shaw T, Smith F, Wood N; DVC Research/Research Network Scheme (SyReNS).

2011

  • Practitioner Fellowship Level 1; Iredell J; National Health and Medical Research Council (NHMRC)/Career Awards: Practitioner Fellowships.
  • Microevolution and transmission of MRSA in a hospital setting; Gilbert G, Sintchenko V, O'Sullivan M, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.

2010

  • Centre for Research Excellence in Critical and Emerging Infectious Diseases; Iredell J, Jones C, Sorrell T, Gilbert G, Kerridge I, Booy R, Dwyer D, Sintchenko V, Bennett B; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • Bacteraemic load and survival in septic shock; Iredell J, Brown S, Webb S, Stanley K, Brown S, Nichol A, Bailey M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • The BD Influx High Speed Cell Sorter; Kefford R, Cunningham A, Bendall L, Clarke C, Harris D, Alexander S, Tam P, Sorrell T, Iredell J, Bryan T, Rizos H, Wang Y, Hebbard L; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2009

  • The ongoing Evolution of Class 1 Integrons and the Recruitment of New Resistance and Virtulence Genes into Pathogens; Gillings M, Stokes H, Holmes A, Iredell J, Partridge S; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Investigation of the Genetic Basis for Microbial Infection and Resistance; Iredell J; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

2008

  • Predicting the risk of invasive candidiasis in critically ill patients; Sorrell T, Jones M, Paterson D, Lipman J, Playford E, Jones M, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Effects of antibiotics on the human microflora; Iredell J, Partridge S, Gidding H, Gilbert G; National Health and Medical Research Council (NHMRC)/Project Grants.

2006

  • Novel, High-Throughput Platform For Rapid Identification, Quantitation, Differential Diagnosis, And Resistance Testing Of Influenza; Iredell J, Dwyer D, Stanley K; National Health and Medical Research Council (NHMRC)/Urgent Research- Pandemic Influenza.

1999

  • Molecular pathogenesis of Bartonella henselae: (cellular invasion and angiogenesis mediated by bacteria); Iredell J; Clive & Vera Ramaciotti Foundation/Research Grants.

Selected publications

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Book Chapters

  • Iredell, J., Partridge, S. (2010). Understanding the Shared Bacterial Genome. In Vitali Sintchenko (Eds.), Infectious Disease Informatics, (pp. 245-261). New York: Springer.
  • Sorrell, T., Mitchell, D., Iredell, J. (2005). Nocardia Species. In Gerald L. Mandell, MD, MACP, John E. Bennett, MD and Raphael Dolin, MD (Eds.), Principles and Practice of Infectious Diseases, (pp. 2916-2924). UK: Churchill Livingstone.
  • Iredell, J., Spelman, D., Sorrell, T. (2005). Septicaemia. In A Yung, D Spelman, A Street, J McCormack, T Sorrell, P Johnson (Eds.), Infectious Diseases: A clinical approach, (pp. 183-193). Melbourne: IP Communications.

Journals

  • Shoma, S., Kamruzzaman, M., Ginn, A., Iredell, J., Partridge, S. (2014). Characterization of multidrug-resistant Klebsiella pneumoniae from Australia carrying blaNDM-1. Diagnostic microbiology and infectious disease, 78(1), 93-97. [More Information]
  • Tagg, K., Iredell, J., Partridge, S. (2014). Complete Sequencing of IncI1 Sequence Type 2 Plasmid pJIE512b Indicates Mobilization of blaCMY-2 from an IncA/C Plasmid. Antimicrobial Agents and Chemotherapy, 58(8), 4949-4952. [More Information]
  • Knox, J., Jadhav, S., Sevior, D., Agyekum, A., Whipp, M., Waring, L., Iredell, J., Palombo, E. (2014). Phenotypic detection of carbapenemase-producing Enterobacteriaceae by use of matrix-assisted laser desorption ionization - Time of flight mass spectrometry and the carba NP test. Journal of Clinical Microbiology, 52(11), 4075-4077. [More Information]
  • Ginn, A., Wiklendt, A., Zong, Z., Lin, R., Teo, J., Tambyah, P., Peterson, L., Kaul, K., Partridge, S., Iredell, J. (2014). Prediction of major antibiotic resistance in Escherichia coli and Klebsiella pneumoniae in Singapore, USA and China using a limited set of gene targets. International Journal of Antimicrobial Agents, 43(6), 563-565. [More Information]
  • Hazelton, B., Thomas, L., Olma, T., Kok, J., O'Sullivan, M., Chen, S., Iredell, J. (2014). Rapid and Accurate Direct Antibiotic Susceptibility Testing of Blood Culture Broths using MALDI Sepsityper combined with the BD Phoenix Automated System. Journal of Medical Microbiology, 63, 1590-1594. [More Information]
  • Gray, T., Thomas, L., Olma, T., Mitchell, D., Iredell, J., Chen, S. (2014). Rapid identification of gram negative bacteria from blood culture broth using maldi-tof mass spectrometry. Journal of Visualized Experiments, 87(87), 51663. [More Information]
  • Guo, X., Dillon, B., Ginn, A., Wiklendt, A., Partridge, S., Iredell, J. (2014). Simple multiplex real-time PCR for rapid detection of common 16S rRNA methyltransferase genes. Diagnostic microbiology and infectious disease, 80(1), 29-31. [More Information]
  • Gilroy, N., Iredell, J. (2014). The clinical and public health challenge of Gram-negative resistance in Australasia. Future Microbiology, 9(1), 17-20. [More Information]
  • Zhou, F., Wang, Q., Sintchenko, V., Gilbert, G., O'Sullivan, M., Iredell, J., Dwyer, D. (2014). Use of the 5' Untranslated Region and VP1 Region to Examine the Molecular Diversity in Enterovirus B Species. Journal of Medical Microbiology, 63(PT10), 1339-1355. [More Information]
  • Kok, J., Chen, S., Dwyer, D., Iredell, J. (2013). Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology, 45(1), 4-17. [More Information]
  • Kamruzzaman, M., Shoma, S., Naymul Bari, S., Ginn, A., Wiklendt, A., Partridge, S., Faruque, S., Iredell, J. (2013). Genetic diversity and antibiotic resistance in Escherichia coli from environmental surface water in Dhaka City, Bangladesh. Diagnostic Microbiology and Infectious Disease, 76(2), 222-226. [More Information]
  • Ginn, A., Zong, Z., Wiklendt, A., Thomas, L., Merlino, J., Gottlieb, T., van Hal, S., Harkness, J., Macleod, C., Bell, S., Partridge, S., Iredell, J., et al (2013). Limited diversity in the gene pool allows prediction of third-generation cephalosporin and aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae. International Journal of Antimicrobial Agents, 42(1), 19-26. [More Information]
  • Gray, T., Thomas, L., Olma, T., Iredell, J., Chen, S. (2013). Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry. Diagnostic Microbiology and Infectious Disease, 77(2), 110-112. [More Information]
  • Hazelton, B., Thomas, L., Unver, T., Iredell, J. (2013). Rapid identification of Gram-positive pathogens and their resistance genes from positive blood culture broth using a multiplex tandem RT-PCR assay. Journal of Medical Microbiology, 62, 223-231. [More Information]
  • Blyth, C., Webb, S., Kok, J., Dwyer, D., van Hal, S., Foo, H., Ginn, A., Kesson, A., Seppelt, I., Iredell, J. (2013). The impact of bacterial and viral co-infection in severe influenza. Influenza and Other Respiratory Viruses, 7(2), 168-176. [More Information]
  • Kok, J., Blyth, C., Foo, H., Bailey, M., Pilcher, D., Webb, S., Seppelt, I., Dwyer, D., Iredell, J. (2013). Viral Pneumonitis Is Increased in Obese Patients during the First Wave of Pandemic A(H1N1) 2009 Virus. PloS One, 8(2), 1-9. [More Information]
  • Partridge, S., Iredell, J. (2012). Genetic Contexts of blaNDM-1. Antimicrobial Agents and Chemotherapy, 56(11), 6065-6067. [More Information]
  • Partridge, S., Ginn, A., Paulsen, I., Iredell, J. (2012). pEl1573 carrying blaIMP-4, from Sydney, Australia, is closely related to other IncL/M plasmids. Antimicrobial Agents and Chemotherapy, 56(11), 6029-6032. [More Information]
  • Partridge, S., Paulsen, I., Iredell, J. (2012). pJIE137 Carrying blaCTX-M-62 Is Closely Related to p271A Carrying blaNDM-1. Antimicrobial Agents and Chemotherapy, 56(4), 2166-2168. [More Information]
  • Ginn, A., Wiklendt, A., Gidding, H., George, N., O'Driscoll, J., Partridge, S., O'Toole, B., Perri, R., Faoagali, J., Gallagher, J., Iredell, J., et al (2012). The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection. PloS One, 7(6), 1-10. [More Information]
  • Partridge, S., Thomas, L., Ginn, A., Wiklendt, A., Kyme, P., Iredell, J. (2011). A Novel Gene Cassette, aacA43, in a Plasmid-Borne Class 1 Integron. Antimicrobial Agents and Chemotherapy, 55(6), 2979-2982. [More Information]
  • Khawaldeh, A., Morales, S., Dillon, B., Alavidze, Z., Ginn, A., Thomas, L., Chapman, S., Dublanchet, A., Smithyman, A., Iredell, J. (2011). Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection. Journal of Medical Microbiology, 60(11), 1697-1700. [More Information]
  • Mascarelli, P., Iredell, J., Maggi, R., Weinberg, G., Breitschwerdt, E. (2011). Bartonella species bacteremia in two patients with epithelioid hemangioendothelioma. Journal of Clinical Microbiology, 49(11), 4006-4012. [More Information]
  • Partridge, S., Ellem, J., Tetu, S., Zong, Z., Paulsen, I., Iredell, J. (2011). Complete Sequence of pJIE143, a pir-Type Plasmid Carrying IS Ecp1-blaCTX-M-15 from an Escherichia coli ST131 Isolate. Antimicrobial Agents and Chemotherapy, 55(12), 5933-5935. [More Information]
  • Tsafnat, G., Schaeffer, J., Clayphan, A., Iredell, J., Partridge, S., Coiera, E. (2011). Computational inference of grammars for larger-than-gene structures from annotated gene sequences. Bioinformatics, 27(6), 791-796. [More Information]
  • Lawson, T., Connally, R., Iredell, J., Vemulpad, S., Piper, J. (2011). Detection of Staphylococcus aureus With a Fluorescence In Situ Hybridization That Does Not Require Lysostaphin. Journal of Clinical Laboratory Analysis, 25(2), 142-147. [More Information]
  • Ellem, J., Partridge, S., Iredell, J. (2011). Efficient Direct Extended-Spectrum B-Lactamase Detection by Multiplex Real-Time PCR: Accurate Assignment of Phenotype by Use of a Limited Set of Genetic Markers. Journal of Clinical Microbiology, 49(8), 3074-3077. [More Information]
  • Betteridge, T., Partridge, S., Iredell, J., Stokes, H. (2011). Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit. Antimicrobial Agents and Chemotherapy, 55(8), 3939-3943. [More Information]
  • Kok, J., Thomas, L., Olma, T., Chen, S., Iredell, J. (2011). Identification of bacteria in blood culture broths using matrix-assisted laser desorption-ionization sepsityperTM and time of flight mass spectrometry. PloS One, 6(8), e23285 - 1-e23285 - 7. [More Information]
  • Lawson, T., Connally, R., Vemulpad, S., Piper, J., Iredell, J. (2011). In reference to targeted imaging modality selection for bacterial biofilms in chronic rhinosinusitis and different biofilms, different disease? a clinical outcomes study. The Laryngoscope, 121(9), 2043-2044. [More Information]
  • Pinto, A., Halliday, C., Zahra, M., van Hal, S., Olma, T., Maszewska, K., Iredell, J., Meyer, W., Chen, S. (2011). Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Identification of Yeasts Is Contingent on Robust Reference Spectra. PloS One, 6(10), e25712-1-e25712-7. [More Information]
  • Partridge, S., Zong, Z., Iredell, J. (2011). Recombination in IS26 and Tn2 in the Evolution of Multi-Resistance Regions Carrying blaCTX-M-15 on Conjugative IncF Plasmids from Escherichia coli. Antimicrobial Agents and Chemotherapy, 55(11), 4971-4978. [More Information]
  • Lawson, T., Connally, R., Iredell, J., Piper, J. (2011). The Simultaneous Detection and Differentiation of Staphylococcus Species in Blood Cultures Using Fluorescence in situ Hybridization: A Comment. Medical Principles and Practice, 20(4), 390-391. [More Information]
  • Kok, J., Blyth, C., Foo, H., Patterson, J., Taylor, J., McPhie, K., Ratnamohan, M., Iredell, J., Dwyer, D. (2010). Comparison of a Rapid Antigen Test with Nucleic Acid Testing During Cocirculation of Pandemic Influenza A/H1N1 2009 and Seasonal Influenza A/H3N2. Journal of Clinical Microbiology, 48(1), 290-291. [More Information]
  • Zong, Z., Partridge, S., Iredell, J. (2010). ISEcp1-Mediated Transposition and Homologous Recombination Can Explain the Context of blaCTX-M-62 Linked to qnrB2. Antimicrobial Agents and Chemotherapy, 54(7), 3039-3042. [More Information]
  • Szewczuk, E., Thapa, K., Anninos, T., McPhie, K., Higgins, G., Dwyer, D., Stanley, K., Iredell, J. (2010). Rapid semi-automated quantitative multiplex tandem PCR (MT-PCR) assays for the differential diagnosis of influenza-like illness. BMC Infectious Diseases, 10(113), 113-1-113-12. [More Information]
  • Zong, Z., Partridge, S., Iredell, J. (2009). A blaVEB-1 Variant, blaVEB-6, Associated with Repeated Elements in a Complex Genetic Structure. Antimicrobial Agents and Chemotherapy, 53(4), 1693-1697. [More Information]
  • Bouchillon, S., Iredell, J., Barkham, T., Kyungwon, L., Dowzicky, M. (2009). Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST). International Journal of Antimicrobial Agents, 33(2), 130-136. [More Information]
  • Tsafnat, G., Coiera, E., Partridge, S., Schaeffer, J., Iredell, J. (2009). Context-driven discovery of gene cassettes in mobile integrons using a computational grammar. BMC Bioinformatics, 10, 281-1-281-9. [More Information]
  • Finfer, S., Seppelt, I., Iredell, J., Webb, S., Petilla, V., Bellomo, R., Cretikos, M., Bailey, M., Cooper, D., Davies, A., et al (2009). Critical care services and 2009 H1N1 influenza in Australia and New Zealand. New England Journal of Medicine, 361(20), 1925-1934. [More Information]
  • Partridge, S., Tsafnat, G., Coiera, E., Iredell, J. (2009). Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiology Reviews, 33(4), 757-784. [More Information]
  • van Hal, S., Wiklendt, A., Espedido, B., Ginn, A., Iredell, J. (2009). Immediate Appearance of Plasmid-Mediated Resistance to Multiple Antibiotics upon Antibiotic Selection: an Argument for Systematic Resistance Epidemiology. Journal of Clinical Microbiology, 47(7), 2325-2327. [More Information]
  • Jiang, X., Espedido, B., Partridge, S., Thomas, L., Wang, F., Iredell, J. (2009). Paradoxical effect of Klebsiella pneumoniae OmpK36 porin deficiency. Pathology, 41(4), 388-392. [More Information]
  • Chatterjee, I., Dulhunty, J., Iredell, J., Gallagher, J., Sud, A., Woods, M., Lipman, J. (2009). Predictors and outcome associated with an Enterococcus positive isolate during intensive care unit admission. Anaesthesia and Intensive Care, 37(6), 976-982. [More Information]
  • Blyth, C., Iredell, J., Dwyer, D. (2009). Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans. The New England Journal of Medicine, 361(25), 2493. [More Information]
  • Zong, Z., Lü, X., Valenzuela, J., Partridge, S., Iredell, J. (2008). An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China. International Journal of Antimicrobial Agents, 31(1), 50-54. [More Information]
  • Espedido, B., Partridge, S., Iredell, J. (2008). blaIMP-4 in different genetic contexts in Enterobacteriaceae Isolates from Australia. Antimicrobial Agents and Chemotherapy, 52(8), 2984-2987. [More Information]
  • Zong, Z., Partridge, S., Thomas, L., Iredell, J. (2008). Dominance of blaCTX-M within an Australian Extended-Spectrum {beta}-Lactamase Gene Pool. Antimicrobial Agents and Chemotherapy, 52(11), 4198-4202. [More Information]
  • Thomas, L., van Hal, S., O'Sullivan, M., Kyme, P., Iredell, J. (2008). Failure of the BD GeneOhm(R) StaphS/R assay for Identification of Australian Methicillin-Resistant Staphylococcus aureus strains: duplex assays remain the 'gold standard' in settings of unknown SCCmec epidemiology. Journal of Clinical Microbiology, 46(12), 4116-4117. [More Information]
  • Chapman, S., Iredell, J. (2008). Gram-negative sepsis in the intensive care unit: avoiding therapeutic failure. Current Opinion in Infectious Diseases, 21(6), 604-609. [More Information]
  • Syrmis, M., Bell, S., Bye, P., Coulter, C., Harbour, C., Iredell, J., Kidd, T., O'Carroll, M., Rose, B., Wainwright, C., Nissen, M., et al (2008). High prevalence of a class 1 integron-associated aadB gene cassette in Pseudomonas aeruginosa isolates from an Australian cystic fibrosis patient population. Pathology, 40(5), 524-525. [More Information]
  • Treerat, P., Widmer, A., Middleton, P., Iredell, J., George, A. (2008). In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS Microbiology Letters, 285(12), 40-50. [More Information]
  • Xu, X., Kong, F., Cheng, X., Yan, B., Du, X., Gai, J., Ai, H., Shi, L., Iredell, J. (2008). Integron gene cassettes in Acinetobacter spp. strains from South China. International Journal of Antimicrobial Agents, 32(5), 441-445. [More Information]
  • Lau, A., Sorrell, T., Chen, S., Stanley, K., Iredell, J., Halliday, C. (2008). Multiplex-Tandem PCR: A Novel Platform for the Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens. Journal of Clinical Microbiology, 46(9), 3021-3027. [More Information]
  • Playford, E., Craig, J., Iredell, J. (2007). Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: risk factors for acquisition, infection and their consequences. Journal of hospital infection. [More Information]
  • Espedido, B., Thomas, L., Iredell, J. (2007). Metallo-beta-lactamase or extended-spectrum beta-lactamase: a wolf in sheep's clothing. Journal of Clinical Microbiology, 45(6), 2034-2036. [More Information]
  • Iredell, J. (2007). Optimizing antipseudomonal therapy in critical care. Seminars in Respiratory and Critical Care Medicine. [More Information]
  • Sintchenko, V., Iredell, J., Gilbert, G. (2007). Pathogen profiling for disease management and surveillance. Nature Reviews Microbiology, 5(6), 464-470. [More Information]
  • Yiasemides, E., Partridge, S., Iredell, J. (2007). RmtC 16S rRNA methyltransferase in Australia. Antimicrobial Agents and Chemotherapy, 52, 794-5. [More Information]
  • Chatterjee, I., Iredell, J., Woods, M., Lipman, J. (2007). The implications of enterococci for the intensive care unit. Critical Care and Resuscitation, 9(1), 69-75. [More Information]
  • Iredell, J., Thomas, L., Power, D., Mendes, E. (2007). Tigecycline resistance in Australian antibiotic-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy, 59. [More Information]
  • Pendlebury, S., Ginn, A., Iredell, J. (2006). Antimicrobial susceptibility of Bartonella henselae using Etest methodology. Journal of Antimicrobial Chemotherapy, 57(4), 761-763. [More Information]
  • Iredell, J., Thomas, L., Espedido, B. (2006). Beta-lactam resistance in the gram negatives: increasing complexity of conditional, composite and multiply resistant phenotypes. Pathology, 38(6), 498-506. [More Information]
  • Thomas, L., Gidding, H., Ginn, A., Olma, T., Iredell, J. (2006). Development of a real-time Staphylococcus aureus and MRSA (SAM-) PCR for routine blood culture. Journal of Microbiological Methods, 68(2), 296-302. [More Information]
  • Valenzuela, J., Thomas, L., Partridge, S., van der Reijden, T., Dijkshoorn, L., Iredell, J. (2006). Horizontal gene transfer within a polyclonal outbreak of carbapenem-resistant Acinetobacter baumannii. Journal of Clinical Microbiology, 45(2), 453-460. [More Information]
  • Iredell, J., Sintchenko, V. (2006). Screening for antibiotic resistant Gram-negative bacteria. The Lancet Infectious Diseases, 6, 316-317. [More Information]
  • Iredell, J., Lipman, J. (2005). Antibiotic resistance in the intensive care unit: a primer in bacteriology. Anaesthesia and Intensive Care, 33(2), 188-95. [More Information]
  • Thomas, L., Watson, S., Iredell, J. (2005). Forewarned is forearmed: antibiotic resistance gene surveillance in critical care. Journal of hospital infection, 60(3), 291-3. [More Information]
  • Sintchenko, V., Iredell, J., Gilbert, G., Coiera, E. (2005). Handheld computer-based decision support reduces patient length of stay and antibiotic prescribing in critical care. Journal of the American Medical Informatics Association, 12(4), 398-402. [More Information]
  • Thomas, L., Iredell, J., Dillon, B., Mohmand, G., Zelynski, A. (2005). Multiplex PCR for screening of integrons in bacterial lysates. Journal of Microbiological Methods, 62(2), 221-32. [More Information]
  • Cachia, A., Eshoo, S., Kench, J., Fung, C., Jones, A., Iredell, J., Don, G. (2005). Synchronous malakoplakia and Whipple's disease. Pathology, 37(4), 315-7. [More Information]
  • Kyme, P., Haas, A., Schaller, M., Peschel, A., Iredell, J., Kempf, V. (2005). Unusual trafficking pattern of Bartonella henselae-containing vacuoles in macrophages and endothelial cells. Cellular Microbiology, 7(7), 1019-1034.
  • Espedido, B., Iredell, J., Thomas, L. (2005). Wide dissemination of a carbapenemase plasmid among gram-negative bacteria: implications of the variable phenotype. Journal of Clinical Microbiology, 43(9), 4918-9. [More Information]
  • Sintchenko, V., Coiera, E., Iredell, J., Gilbert, G. (2004). Comparative Impact Of Guidelines, Clinical Data, And Decision Support On Prescribing Decisions: An Interactive Web Experiment With Simulated Cases. Journal of the American Medical Informatics Association, 11(1), 71-77.
  • Rodrick, D., Dillon, B., Dexter, M., Nicholson, I., Marcel, S., Dickeson, D., Iredell, J. (2004). Culture-Negative Endocarditis Due To Houston Complex Bartonella Henselae Acquired In Noumea, New Caledonia. Journal of Clinical Microbiology, 42(4), 1846-1848.
  • Iredell, J., Blanckenberg, D., Arvand, M., Grauling, S., Feil, E., Birtles, R. (2003). Characterization of the natural population of bartonella henselae by multilocus sequence typing. Journal of Clinical Microbiology, 41(11), 5071-5079.
  • Kyme, P., Dillon, B., Iredell, J. (2003). Phase variation in bartonella henselae. Microbiology, 149(3), 621-629.
  • Iredell, J., Kyme, P., Blanckenberg, D., McHattan,, J., Dillon, B. (2002). Antigenic and Genotypic Relationships between Bartonella henselae Strains. Journal of Clinical Microbiology, , 4397-4398.
  • Dillon, B., Valenzuela, J., Don, R., Blanckenberg, D., Wigney, D., Malik, R., Morris, A., Robson, J., Iredell, J. (2002). Limited Diversity among Human isolates of Bartonella henselae. Journal of Clinical Microbiology, 40(12), 4691-4699.
  • Arora, S., Mudaliar, Y., Lee, C., Mitchell, D., Iredell, J., Lazarus, R. (2002). Non-Bronchoscopic Bronchoalveolar Lavage in the Microbiological Diagnosis of Pneumonia in Mechanically Ventilated Patients. Anaesthesia and Intensive Care, 30(1), 11-20.
  • Kyme, P., Dillon, B., Iredell, J. (2002). Phase variation in Bartonella heselae. Microbiology, 149(3), 621-629.
  • Iredell, J., Gilbert, G., Sintchenko, V. (2001). Antibiotic therapy of ventilator-associated pneumonia - a reappraisal of rationale in the era of bacterial resistance. International Journal of Antimicrobial Agents, 18, 223-229.
  • Iredell, J., Gilbert, G., Sintchenko, V., Coiera, E. (2001). What do physicians think about evidence-based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners. Internal Medicine Journal, 31, 462-469.

Conferences

  • Playford, E., Craig, J., Simpson, J., Iredell, J. (2003). Carbapenem Resistant Acinetobacter baumannii (CR-AB) in ICU patients: Attributable mortality and length of stay. 43rd ICAAC, American Society for Microbiology.
  • Playford, E., Craig, J., Simpson, J., Iredell, J. (2003). Carbapenem Resistant Acinetobacter baumannii (CR-AB): Risk factors for acquisition and infection amongst ICU patients. 43rd ICAAC, American Society for Microbiology.

2014

  • Shoma, S., Kamruzzaman, M., Ginn, A., Iredell, J., Partridge, S. (2014). Characterization of multidrug-resistant Klebsiella pneumoniae from Australia carrying blaNDM-1. Diagnostic microbiology and infectious disease, 78(1), 93-97. [More Information]
  • Tagg, K., Iredell, J., Partridge, S. (2014). Complete Sequencing of IncI1 Sequence Type 2 Plasmid pJIE512b Indicates Mobilization of blaCMY-2 from an IncA/C Plasmid. Antimicrobial Agents and Chemotherapy, 58(8), 4949-4952. [More Information]
  • Knox, J., Jadhav, S., Sevior, D., Agyekum, A., Whipp, M., Waring, L., Iredell, J., Palombo, E. (2014). Phenotypic detection of carbapenemase-producing Enterobacteriaceae by use of matrix-assisted laser desorption ionization - Time of flight mass spectrometry and the carba NP test. Journal of Clinical Microbiology, 52(11), 4075-4077. [More Information]
  • Ginn, A., Wiklendt, A., Zong, Z., Lin, R., Teo, J., Tambyah, P., Peterson, L., Kaul, K., Partridge, S., Iredell, J. (2014). Prediction of major antibiotic resistance in Escherichia coli and Klebsiella pneumoniae in Singapore, USA and China using a limited set of gene targets. International Journal of Antimicrobial Agents, 43(6), 563-565. [More Information]
  • Hazelton, B., Thomas, L., Olma, T., Kok, J., O'Sullivan, M., Chen, S., Iredell, J. (2014). Rapid and Accurate Direct Antibiotic Susceptibility Testing of Blood Culture Broths using MALDI Sepsityper combined with the BD Phoenix Automated System. Journal of Medical Microbiology, 63, 1590-1594. [More Information]
  • Gray, T., Thomas, L., Olma, T., Mitchell, D., Iredell, J., Chen, S. (2014). Rapid identification of gram negative bacteria from blood culture broth using maldi-tof mass spectrometry. Journal of Visualized Experiments, 87(87), 51663. [More Information]
  • Guo, X., Dillon, B., Ginn, A., Wiklendt, A., Partridge, S., Iredell, J. (2014). Simple multiplex real-time PCR for rapid detection of common 16S rRNA methyltransferase genes. Diagnostic microbiology and infectious disease, 80(1), 29-31. [More Information]
  • Gilroy, N., Iredell, J. (2014). The clinical and public health challenge of Gram-negative resistance in Australasia. Future Microbiology, 9(1), 17-20. [More Information]
  • Zhou, F., Wang, Q., Sintchenko, V., Gilbert, G., O'Sullivan, M., Iredell, J., Dwyer, D. (2014). Use of the 5' Untranslated Region and VP1 Region to Examine the Molecular Diversity in Enterovirus B Species. Journal of Medical Microbiology, 63(PT10), 1339-1355. [More Information]

2013

  • Kok, J., Chen, S., Dwyer, D., Iredell, J. (2013). Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory. Pathology, 45(1), 4-17. [More Information]
  • Kamruzzaman, M., Shoma, S., Naymul Bari, S., Ginn, A., Wiklendt, A., Partridge, S., Faruque, S., Iredell, J. (2013). Genetic diversity and antibiotic resistance in Escherichia coli from environmental surface water in Dhaka City, Bangladesh. Diagnostic Microbiology and Infectious Disease, 76(2), 222-226. [More Information]
  • Ginn, A., Zong, Z., Wiklendt, A., Thomas, L., Merlino, J., Gottlieb, T., van Hal, S., Harkness, J., Macleod, C., Bell, S., Partridge, S., Iredell, J., et al (2013). Limited diversity in the gene pool allows prediction of third-generation cephalosporin and aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae. International Journal of Antimicrobial Agents, 42(1), 19-26. [More Information]
  • Gray, T., Thomas, L., Olma, T., Iredell, J., Chen, S. (2013). Rapid identification of Gram-negative organisms from blood culture bottles using a modified extraction method and MALDI-TOF mass spectrometry. Diagnostic Microbiology and Infectious Disease, 77(2), 110-112. [More Information]
  • Hazelton, B., Thomas, L., Unver, T., Iredell, J. (2013). Rapid identification of Gram-positive pathogens and their resistance genes from positive blood culture broth using a multiplex tandem RT-PCR assay. Journal of Medical Microbiology, 62, 223-231. [More Information]
  • Blyth, C., Webb, S., Kok, J., Dwyer, D., van Hal, S., Foo, H., Ginn, A., Kesson, A., Seppelt, I., Iredell, J. (2013). The impact of bacterial and viral co-infection in severe influenza. Influenza and Other Respiratory Viruses, 7(2), 168-176. [More Information]
  • Kok, J., Blyth, C., Foo, H., Bailey, M., Pilcher, D., Webb, S., Seppelt, I., Dwyer, D., Iredell, J. (2013). Viral Pneumonitis Is Increased in Obese Patients during the First Wave of Pandemic A(H1N1) 2009 Virus. PloS One, 8(2), 1-9. [More Information]

2012

  • Partridge, S., Iredell, J. (2012). Genetic Contexts of blaNDM-1. Antimicrobial Agents and Chemotherapy, 56(11), 6065-6067. [More Information]
  • Partridge, S., Ginn, A., Paulsen, I., Iredell, J. (2012). pEl1573 carrying blaIMP-4, from Sydney, Australia, is closely related to other IncL/M plasmids. Antimicrobial Agents and Chemotherapy, 56(11), 6029-6032. [More Information]
  • Partridge, S., Paulsen, I., Iredell, J. (2012). pJIE137 Carrying blaCTX-M-62 Is Closely Related to p271A Carrying blaNDM-1. Antimicrobial Agents and Chemotherapy, 56(4), 2166-2168. [More Information]
  • Ginn, A., Wiklendt, A., Gidding, H., George, N., O'Driscoll, J., Partridge, S., O'Toole, B., Perri, R., Faoagali, J., Gallagher, J., Iredell, J., et al (2012). The Ecology of Antibiotic Use in the ICU: Homogeneous Prescribing of Cefepime but Not Tazocin Selects for Antibiotic Resistant Infection. PloS One, 7(6), 1-10. [More Information]

2011

  • Partridge, S., Thomas, L., Ginn, A., Wiklendt, A., Kyme, P., Iredell, J. (2011). A Novel Gene Cassette, aacA43, in a Plasmid-Borne Class 1 Integron. Antimicrobial Agents and Chemotherapy, 55(6), 2979-2982. [More Information]
  • Khawaldeh, A., Morales, S., Dillon, B., Alavidze, Z., Ginn, A., Thomas, L., Chapman, S., Dublanchet, A., Smithyman, A., Iredell, J. (2011). Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection. Journal of Medical Microbiology, 60(11), 1697-1700. [More Information]
  • Mascarelli, P., Iredell, J., Maggi, R., Weinberg, G., Breitschwerdt, E. (2011). Bartonella species bacteremia in two patients with epithelioid hemangioendothelioma. Journal of Clinical Microbiology, 49(11), 4006-4012. [More Information]
  • Partridge, S., Ellem, J., Tetu, S., Zong, Z., Paulsen, I., Iredell, J. (2011). Complete Sequence of pJIE143, a pir-Type Plasmid Carrying IS Ecp1-blaCTX-M-15 from an Escherichia coli ST131 Isolate. Antimicrobial Agents and Chemotherapy, 55(12), 5933-5935. [More Information]
  • Tsafnat, G., Schaeffer, J., Clayphan, A., Iredell, J., Partridge, S., Coiera, E. (2011). Computational inference of grammars for larger-than-gene structures from annotated gene sequences. Bioinformatics, 27(6), 791-796. [More Information]
  • Lawson, T., Connally, R., Iredell, J., Vemulpad, S., Piper, J. (2011). Detection of Staphylococcus aureus With a Fluorescence In Situ Hybridization That Does Not Require Lysostaphin. Journal of Clinical Laboratory Analysis, 25(2), 142-147. [More Information]
  • Ellem, J., Partridge, S., Iredell, J. (2011). Efficient Direct Extended-Spectrum B-Lactamase Detection by Multiplex Real-Time PCR: Accurate Assignment of Phenotype by Use of a Limited Set of Genetic Markers. Journal of Clinical Microbiology, 49(8), 3074-3077. [More Information]
  • Betteridge, T., Partridge, S., Iredell, J., Stokes, H. (2011). Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit. Antimicrobial Agents and Chemotherapy, 55(8), 3939-3943. [More Information]
  • Kok, J., Thomas, L., Olma, T., Chen, S., Iredell, J. (2011). Identification of bacteria in blood culture broths using matrix-assisted laser desorption-ionization sepsityperTM and time of flight mass spectrometry. PloS One, 6(8), e23285 - 1-e23285 - 7. [More Information]
  • Lawson, T., Connally, R., Vemulpad, S., Piper, J., Iredell, J. (2011). In reference to targeted imaging modality selection for bacterial biofilms in chronic rhinosinusitis and different biofilms, different disease? a clinical outcomes study. The Laryngoscope, 121(9), 2043-2044. [More Information]
  • Pinto, A., Halliday, C., Zahra, M., van Hal, S., Olma, T., Maszewska, K., Iredell, J., Meyer, W., Chen, S. (2011). Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Identification of Yeasts Is Contingent on Robust Reference Spectra. PloS One, 6(10), e25712-1-e25712-7. [More Information]
  • Partridge, S., Zong, Z., Iredell, J. (2011). Recombination in IS26 and Tn2 in the Evolution of Multi-Resistance Regions Carrying blaCTX-M-15 on Conjugative IncF Plasmids from Escherichia coli. Antimicrobial Agents and Chemotherapy, 55(11), 4971-4978. [More Information]
  • Lawson, T., Connally, R., Iredell, J., Piper, J. (2011). The Simultaneous Detection and Differentiation of Staphylococcus Species in Blood Cultures Using Fluorescence in situ Hybridization: A Comment. Medical Principles and Practice, 20(4), 390-391. [More Information]

2010

  • Kok, J., Blyth, C., Foo, H., Patterson, J., Taylor, J., McPhie, K., Ratnamohan, M., Iredell, J., Dwyer, D. (2010). Comparison of a Rapid Antigen Test with Nucleic Acid Testing During Cocirculation of Pandemic Influenza A/H1N1 2009 and Seasonal Influenza A/H3N2. Journal of Clinical Microbiology, 48(1), 290-291. [More Information]
  • Zong, Z., Partridge, S., Iredell, J. (2010). ISEcp1-Mediated Transposition and Homologous Recombination Can Explain the Context of blaCTX-M-62 Linked to qnrB2. Antimicrobial Agents and Chemotherapy, 54(7), 3039-3042. [More Information]
  • Szewczuk, E., Thapa, K., Anninos, T., McPhie, K., Higgins, G., Dwyer, D., Stanley, K., Iredell, J. (2010). Rapid semi-automated quantitative multiplex tandem PCR (MT-PCR) assays for the differential diagnosis of influenza-like illness. BMC Infectious Diseases, 10(113), 113-1-113-12. [More Information]
  • Iredell, J., Partridge, S. (2010). Understanding the Shared Bacterial Genome. In Vitali Sintchenko (Eds.), Infectious Disease Informatics, (pp. 245-261). New York: Springer.

2009

  • Zong, Z., Partridge, S., Iredell, J. (2009). A blaVEB-1 Variant, blaVEB-6, Associated with Repeated Elements in a Complex Genetic Structure. Antimicrobial Agents and Chemotherapy, 53(4), 1693-1697. [More Information]
  • Bouchillon, S., Iredell, J., Barkham, T., Kyungwon, L., Dowzicky, M. (2009). Comparative in vitro activity of tigecycline and other antimicrobials against Gram-negative and Gram-positive organisms collected from the Asia-Pacific Rim as part of the Tigecycline Evaluation and Surveillance Trial (TEST). International Journal of Antimicrobial Agents, 33(2), 130-136. [More Information]
  • Tsafnat, G., Coiera, E., Partridge, S., Schaeffer, J., Iredell, J. (2009). Context-driven discovery of gene cassettes in mobile integrons using a computational grammar. BMC Bioinformatics, 10, 281-1-281-9. [More Information]
  • Finfer, S., Seppelt, I., Iredell, J., Webb, S., Petilla, V., Bellomo, R., Cretikos, M., Bailey, M., Cooper, D., Davies, A., et al (2009). Critical care services and 2009 H1N1 influenza in Australia and New Zealand. New England Journal of Medicine, 361(20), 1925-1934. [More Information]
  • Partridge, S., Tsafnat, G., Coiera, E., Iredell, J. (2009). Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiology Reviews, 33(4), 757-784. [More Information]
  • van Hal, S., Wiklendt, A., Espedido, B., Ginn, A., Iredell, J. (2009). Immediate Appearance of Plasmid-Mediated Resistance to Multiple Antibiotics upon Antibiotic Selection: an Argument for Systematic Resistance Epidemiology. Journal of Clinical Microbiology, 47(7), 2325-2327. [More Information]
  • Jiang, X., Espedido, B., Partridge, S., Thomas, L., Wang, F., Iredell, J. (2009). Paradoxical effect of Klebsiella pneumoniae OmpK36 porin deficiency. Pathology, 41(4), 388-392. [More Information]
  • Chatterjee, I., Dulhunty, J., Iredell, J., Gallagher, J., Sud, A., Woods, M., Lipman, J. (2009). Predictors and outcome associated with an Enterococcus positive isolate during intensive care unit admission. Anaesthesia and Intensive Care, 37(6), 976-982. [More Information]
  • Blyth, C., Iredell, J., Dwyer, D. (2009). Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans. The New England Journal of Medicine, 361(25), 2493. [More Information]

2008

  • Zong, Z., Lü, X., Valenzuela, J., Partridge, S., Iredell, J. (2008). An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China. International Journal of Antimicrobial Agents, 31(1), 50-54. [More Information]
  • Espedido, B., Partridge, S., Iredell, J. (2008). blaIMP-4 in different genetic contexts in Enterobacteriaceae Isolates from Australia. Antimicrobial Agents and Chemotherapy, 52(8), 2984-2987. [More Information]
  • Zong, Z., Partridge, S., Thomas, L., Iredell, J. (2008). Dominance of blaCTX-M within an Australian Extended-Spectrum {beta}-Lactamase Gene Pool. Antimicrobial Agents and Chemotherapy, 52(11), 4198-4202. [More Information]
  • Thomas, L., van Hal, S., O'Sullivan, M., Kyme, P., Iredell, J. (2008). Failure of the BD GeneOhm(R) StaphS/R assay for Identification of Australian Methicillin-Resistant Staphylococcus aureus strains: duplex assays remain the 'gold standard' in settings of unknown SCCmec epidemiology. Journal of Clinical Microbiology, 46(12), 4116-4117. [More Information]
  • Chapman, S., Iredell, J. (2008). Gram-negative sepsis in the intensive care unit: avoiding therapeutic failure. Current Opinion in Infectious Diseases, 21(6), 604-609. [More Information]
  • Syrmis, M., Bell, S., Bye, P., Coulter, C., Harbour, C., Iredell, J., Kidd, T., O'Carroll, M., Rose, B., Wainwright, C., Nissen, M., et al (2008). High prevalence of a class 1 integron-associated aadB gene cassette in Pseudomonas aeruginosa isolates from an Australian cystic fibrosis patient population. Pathology, 40(5), 524-525. [More Information]
  • Treerat, P., Widmer, A., Middleton, P., Iredell, J., George, A. (2008). In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS Microbiology Letters, 285(12), 40-50. [More Information]
  • Xu, X., Kong, F., Cheng, X., Yan, B., Du, X., Gai, J., Ai, H., Shi, L., Iredell, J. (2008). Integron gene cassettes in Acinetobacter spp. strains from South China. International Journal of Antimicrobial Agents, 32(5), 441-445. [More Information]
  • Lau, A., Sorrell, T., Chen, S., Stanley, K., Iredell, J., Halliday, C. (2008). Multiplex-Tandem PCR: A Novel Platform for the Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens. Journal of Clinical Microbiology, 46(9), 3021-3027. [More Information]

2007

  • Playford, E., Craig, J., Iredell, J. (2007). Carbapenem-resistant Acinetobacter baumannii in intensive care unit patients: risk factors for acquisition, infection and their consequences. Journal of hospital infection. [More Information]
  • Espedido, B., Thomas, L., Iredell, J. (2007). Metallo-beta-lactamase or extended-spectrum beta-lactamase: a wolf in sheep's clothing. Journal of Clinical Microbiology, 45(6), 2034-2036. [More Information]
  • Iredell, J. (2007). Optimizing antipseudomonal therapy in critical care. Seminars in Respiratory and Critical Care Medicine. [More Information]
  • Sintchenko, V., Iredell, J., Gilbert, G. (2007). Pathogen profiling for disease management and surveillance. Nature Reviews Microbiology, 5(6), 464-470. [More Information]
  • Yiasemides, E., Partridge, S., Iredell, J. (2007). RmtC 16S rRNA methyltransferase in Australia. Antimicrobial Agents and Chemotherapy, 52, 794-5. [More Information]
  • Chatterjee, I., Iredell, J., Woods, M., Lipman, J. (2007). The implications of enterococci for the intensive care unit. Critical Care and Resuscitation, 9(1), 69-75. [More Information]
  • Iredell, J., Thomas, L., Power, D., Mendes, E. (2007). Tigecycline resistance in Australian antibiotic-resistant Gram-negative bacteria. Journal of Antimicrobial Chemotherapy, 59. [More Information]

2006

  • Pendlebury, S., Ginn, A., Iredell, J. (2006). Antimicrobial susceptibility of Bartonella henselae using Etest methodology. Journal of Antimicrobial Chemotherapy, 57(4), 761-763. [More Information]
  • Iredell, J., Thomas, L., Espedido, B. (2006). Beta-lactam resistance in the gram negatives: increasing complexity of conditional, composite and multiply resistant phenotypes. Pathology, 38(6), 498-506. [More Information]
  • Thomas, L., Gidding, H., Ginn, A., Olma, T., Iredell, J. (2006). Development of a real-time Staphylococcus aureus and MRSA (SAM-) PCR for routine blood culture. Journal of Microbiological Methods, 68(2), 296-302. [More Information]
  • Valenzuela, J., Thomas, L., Partridge, S., van der Reijden, T., Dijkshoorn, L., Iredell, J. (2006). Horizontal gene transfer within a polyclonal outbreak of carbapenem-resistant Acinetobacter baumannii. Journal of Clinical Microbiology, 45(2), 453-460. [More Information]
  • Iredell, J., Sintchenko, V. (2006). Screening for antibiotic resistant Gram-negative bacteria. The Lancet Infectious Diseases, 6, 316-317. [More Information]

2005

  • Iredell, J., Lipman, J. (2005). Antibiotic resistance in the intensive care unit: a primer in bacteriology. Anaesthesia and Intensive Care, 33(2), 188-95. [More Information]
  • Thomas, L., Watson, S., Iredell, J. (2005). Forewarned is forearmed: antibiotic resistance gene surveillance in critical care. Journal of hospital infection, 60(3), 291-3. [More Information]
  • Sintchenko, V., Iredell, J., Gilbert, G., Coiera, E. (2005). Handheld computer-based decision support reduces patient length of stay and antibiotic prescribing in critical care. Journal of the American Medical Informatics Association, 12(4), 398-402. [More Information]
  • Thomas, L., Iredell, J., Dillon, B., Mohmand, G., Zelynski, A. (2005). Multiplex PCR for screening of integrons in bacterial lysates. Journal of Microbiological Methods, 62(2), 221-32. [More Information]
  • Sorrell, T., Mitchell, D., Iredell, J. (2005). Nocardia Species. In Gerald L. Mandell, MD, MACP, John E. Bennett, MD and Raphael Dolin, MD (Eds.), Principles and Practice of Infectious Diseases, (pp. 2916-2924). UK: Churchill Livingstone.
  • Iredell, J., Spelman, D., Sorrell, T. (2005). Septicaemia. In A Yung, D Spelman, A Street, J McCormack, T Sorrell, P Johnson (Eds.), Infectious Diseases: A clinical approach, (pp. 183-193). Melbourne: IP Communications.
  • Cachia, A., Eshoo, S., Kench, J., Fung, C., Jones, A., Iredell, J., Don, G. (2005). Synchronous malakoplakia and Whipple's disease. Pathology, 37(4), 315-7. [More Information]
  • Kyme, P., Haas, A., Schaller, M., Peschel, A., Iredell, J., Kempf, V. (2005). Unusual trafficking pattern of Bartonella henselae-containing vacuoles in macrophages and endothelial cells. Cellular Microbiology, 7(7), 1019-1034.
  • Espedido, B., Iredell, J., Thomas, L. (2005). Wide dissemination of a carbapenemase plasmid among gram-negative bacteria: implications of the variable phenotype. Journal of Clinical Microbiology, 43(9), 4918-9. [More Information]

2004

  • Sintchenko, V., Coiera, E., Iredell, J., Gilbert, G. (2004). Comparative Impact Of Guidelines, Clinical Data, And Decision Support On Prescribing Decisions: An Interactive Web Experiment With Simulated Cases. Journal of the American Medical Informatics Association, 11(1), 71-77.
  • Rodrick, D., Dillon, B., Dexter, M., Nicholson, I., Marcel, S., Dickeson, D., Iredell, J. (2004). Culture-Negative Endocarditis Due To Houston Complex Bartonella Henselae Acquired In Noumea, New Caledonia. Journal of Clinical Microbiology, 42(4), 1846-1848.

2003

  • Playford, E., Craig, J., Simpson, J., Iredell, J. (2003). Carbapenem Resistant Acinetobacter baumannii (CR-AB) in ICU patients: Attributable mortality and length of stay. 43rd ICAAC, American Society for Microbiology.
  • Playford, E., Craig, J., Simpson, J., Iredell, J. (2003). Carbapenem Resistant Acinetobacter baumannii (CR-AB): Risk factors for acquisition and infection amongst ICU patients. 43rd ICAAC, American Society for Microbiology.
  • Iredell, J., Blanckenberg, D., Arvand, M., Grauling, S., Feil, E., Birtles, R. (2003). Characterization of the natural population of bartonella henselae by multilocus sequence typing. Journal of Clinical Microbiology, 41(11), 5071-5079.
  • Kyme, P., Dillon, B., Iredell, J. (2003). Phase variation in bartonella henselae. Microbiology, 149(3), 621-629.

2002

  • Iredell, J., Kyme, P., Blanckenberg, D., McHattan,, J., Dillon, B. (2002). Antigenic and Genotypic Relationships between Bartonella henselae Strains. Journal of Clinical Microbiology, , 4397-4398.
  • Dillon, B., Valenzuela, J., Don, R., Blanckenberg, D., Wigney, D., Malik, R., Morris, A., Robson, J., Iredell, J. (2002). Limited Diversity among Human isolates of Bartonella henselae. Journal of Clinical Microbiology, 40(12), 4691-4699.
  • Arora, S., Mudaliar, Y., Lee, C., Mitchell, D., Iredell, J., Lazarus, R. (2002). Non-Bronchoscopic Bronchoalveolar Lavage in the Microbiological Diagnosis of Pneumonia in Mechanically Ventilated Patients. Anaesthesia and Intensive Care, 30(1), 11-20.
  • Kyme, P., Dillon, B., Iredell, J. (2002). Phase variation in Bartonella heselae. Microbiology, 149(3), 621-629.

2001

  • Iredell, J., Gilbert, G., Sintchenko, V. (2001). Antibiotic therapy of ventilator-associated pneumonia - a reappraisal of rationale in the era of bacterial resistance. International Journal of Antimicrobial Agents, 18, 223-229.
  • Iredell, J., Gilbert, G., Sintchenko, V., Coiera, E. (2001). What do physicians think about evidence-based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners. Internal Medicine Journal, 31, 462-469.

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