Associate Professor Jonathan Karpelowsky

Conjoint Associate Professor Division of Child and Adolescent Health Children's Hospital Westmead

Telephone +61 2 9845 3235
Fax +61 2 9845 3180

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Biographical details

Jonathan Karpelowsky is a full time academic paediatric surgeon at the Children’s hospital Westmead and Conjoint Associate Professor at the University of Sydney. He undertook both his adult and paediatric surgical training in Cape Town followed by his PhD before being recruited to Sydney in 2010.

His clinical focus is in paediatric surgical oncology and thoracic surgery. He is the principal surgical oncologist and runs a long term follow up clinic for complex surgical thoracic conditions in childhood. His surgical techniques focus on novel minimally invasive surgery and novel techniques for chest wall reconstruction.

Research interests

His cancer research interests include paediatric solid tumours with particular reference to liquid biopsies for the detection of minimal residual disease in paediatric solid tumours , monitoring genetic and disease progression and surgical reconstruction and imaging of tumours to assist in cancer surgery.

His thoracic surgical research focuses on chest wall reconstruction and long term follow up of oesophageal atresia and diaphragmatic hernias.

A/Prof Karpelowsky is also the Principal investigator on a number of clinical trials focusing on common paediatric surgical conditions including central venous access, biliary atresia, appendicitis and pyloric stenosis.

Teaching and supervision

A/Prof Karpelowsky is involved in both undergraduate and post graduate education, and is currently supervising several Masters and Doctoral candidates. In addition to his university activities he is the current chairperson for the Board of Paediatric surgery for The Royal Australasian College of Surgeons and he is on the section of academic surgery committee. He is one of the founders and organisers of an Australasian paediatric solid tumour oncology course which started in 2015. He has given invited talks in Malaysia and Singapore on Neuroblastoma and Hepatoblastoma

Current projects

Liquid Biopsies in paediatric solid tumours

  • Circulating tumour cells
  • Circulating tumour DNA
  • Circularing tumour RNA-mRNA and miRNA

Selected publications

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Journals

  • Soundappan, S., Karpelowsky, J., Lam, A., Lam, L., Cass, D. (2018). Diagnostic accuracy of surgeon performed ultrasound (SPU) for appendicitis in children. Journal of Pediatric Surgery, 53(10), 2023-2027. [More Information]
  • Taylor, N., La Hei, E., Karpelowsky, J. (2018). Oesophageal lung. ANZ Journal of Surgery, 88(1-Feb), 108-110. [More Information]
  • Fitzgerald, D., Kench, A., Hatton, L., Karpelowsky, J. (2018). Strategies for improving early nutritional outcomes in children with oesophageal atresia and congenital diaphragmatic hernia. Paediatric Respiratory Reviews, 25, 85-87. [More Information]
  • Vierboom, L., Darani, A., Langusch, C., Soundappan, S., Karpelowsky, J. (2018). Tunnelled central venous access devices in small children: A comparison of open vs. ultrasound-guided percutaneous insertion in children weighing ten kilograms or less. Journal of Pediatric Surgery, 53(9), 1832-1838. [More Information]
  • Nayak, A., McDowell, D., Kellie, S., Karpelowsky, J. (2017). Elevated Preoperative Neutrophil�Lymphocyte Ratio is Predictive of a Poorer Prognosis for Pediatric Patients with Solid Tumors. Annals of Surgical Oncology, 24(11), 3456-3462. [More Information]
  • Read, A., Xu, J., Adams, S., Karpelowsky, J. (2017). Five lessons in uncomplicated appendicitis: Can we remove the surgery? Journal of Paediatrics and Child Health, 53(11), 1127-1130. [More Information]
  • King, S., Karpelowsky, J. (2017). Hirschsprung disease. ANZ Journal of Surgery, 87(10), 754. [More Information]
  • Gluckman, S., Karpelowsky, J., Webster, A., McGee, R. (2017). Management for intussusception in children. Cochrane Database of Systematic Reviews, 2017 (6), 1-54. [More Information]
  • Xu, J., Adams, S., Liu, Y., Karpelowsky, J. (2017). Nonoperative management in children with early acute appendicitis: A systematic review. Journal of Pediatric Surgery, 52(9), 1409-1415. [More Information]
  • Stephenson, C., Norlen, O., Shun, A., Karpelowsky, J., Robinson, B., Delbridge, L. (2017). Papillary thyroid cancer in childhood: is parental screening helpful? ANZ Journal of Surgery, 87(7-8), 615-618. [More Information]
  • Narayanan, S., Cohen, R., Karpelowsky, J. (2017). Patterns of reflux in gastroesophageal reflux disease in pediatric population of New South Wales. Diseases of the Esophagus, 30(2), 1-8. [More Information]
  • Collin, M., Karpelowsky, J., Thomas, G. (2017). Pediatric transplantation: An international perspective. Seminars in Pediatric Surgery, 26(4), 272-277. [More Information]
  • Ziaziaris, W., Darani, A., Holland, A., Alexander, A., Karpelowsky, J., Barbaro, P., Stormon, M., O�Loughlin, E., Shun, A., Thomas, G. (2017). Reducing the incidence of hepatic artery thrombosis in pediatric liver transplantation: Effect of microvascular techniques and a customized anticoagulation protocol. Pediatric Transplantation, 21(4), 1-7. [More Information]
  • Fitzgerald, D., Karpelowsky, J. (2016). "Oesophageal Atresia- We need to be seeing ya!". Paediatric Respiratory Reviews, 19, 1-2. [More Information]
  • Xu, J., Liu, Y., Adams, S., Karpelowsky, J. (2016). Acute uncomplicated appendicitis study: rationale and protocol for a multicentre, prospective randomised controlled non-inferiority study to evaluate the safety and effectiveness of non-operative management in children with acute uncomplicated appendicitis. BMJ Open, 6(12), 1-8. [More Information]
  • Skowno, J., Karpelowsky, J., Watts, N., Little, D. (2016). Can transcutaneous near infrared spectroscopy detect severe hepatic ischemia: a juvenile porcine model. Paediatric Anaesthesia, 26(12), 1188-1196. [More Information]
  • Kamaraj, S., Arbuckle, S., Arbuckle, S., Smith, G., Karpelowsky, J. (2016). Congenital mesoblastic nephroma presenting with hematuria in a neonate: A case report. Urology, 88, 189-191. [More Information]
  • Roberts, K., Karpelowsky, J., Fitzgerald, D., Sannappa Venkatraman, S. (2016). Outcomes of oesophageal atresia and tracheo-oesophageal fistula repair. Journal of Paediatrics and Child Health, 52(7), 694-698. [More Information]
  • Flower, E., Tran, K., Zanjani, S., Smith, W., Karpelowsky, J., Summerhayes, K., Estoesta, E., Chard, J. (2016). Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms' tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy, 8(5), 429-433. [More Information]
  • Al-lede, M., Karpelowsky, J., Fitzgerald, D. (2016). Recurrent Diaphragmatic Hernia: Modi�?able and Non-Modi�?able Risk Factors. Pediatric Pulmonology, 51(4), 394-401. [More Information]
  • Brown, K., Dunne, B., Festa, M., La Hei, E., Karpelowsky, J., Dando, H., Orr, Y. (2016). Successful 2,000-Kilometer international transfer of an infant receiving extracorporeal membrane oxygenation for severe respiratory failure. The Annals of Thoracic Surgery, 102(2), e131-e133. [More Information]
  • Teague, W., Karpelowsky, J. (2016). Surgical management of oesophageal atresia. Paediatric Respiratory Reviews, 19, 10-15. [More Information]
  • Ziaziaris, W., Darani, A., Holland, A., Alexander, A., Karpelowsky, J., Shun, A., Thomas, G. (2015). Delayed primary closure and the incidence of surgical complications in pediatric liver transplant recipients. Journal of Pediatric Surgery, 50(12), 2137-2140. [More Information]
  • Leeuwen, L., Walker, K., Halliday, R., Karpelowsky, J., Fitzgerald, D. (2014). Growth in children with congenital diaphragmatic hernia during the first year of life. Journal of Pediatric Surgery, 49(9), 1363-1366. [More Information]
  • Skowno, J., Karpelowsky, J. (2014). Near-infrared spectroscopy for monitoring renal transplant perfusion. Pediatric Nephrology, 29(11), 2241-2242. [More Information]
  • Westgarth-Taylor, C., de Lijster, L., van Bogerijen, G., Millar, A., Karpelowsky, J. (2013). A prospective assessment of renal oxygenation in children undergoing laparoscopy using near-infrared spectroscopy. Surgical Endoscopy, 27(10), 3696-3704. [More Information]
  • Wanaguru, D., Shun, A., Price, N., Karpelowsky, J. (2013). Outcomes of pulmonary metastases in hepatoblastoma - is the prognosis always poor? Journal of Pediatric Surgery, 48(12), 2474-2478. [More Information]
  • Karpelowsky, J. (2012). Paediatric Thoracoscopic Surgery. Paediatric Respiratory Reviews, 13(4), 244-251. [More Information]
  • Karpelowsky, J., Thomas, G., Shun, A. (2009). Definitive abdominal wall closure using a porcine intestinal submucosa biodegradable membrane in pediatric transplantation. Pediatric Transplantation, 13(3), 285-289. [More Information]

2018

  • Soundappan, S., Karpelowsky, J., Lam, A., Lam, L., Cass, D. (2018). Diagnostic accuracy of surgeon performed ultrasound (SPU) for appendicitis in children. Journal of Pediatric Surgery, 53(10), 2023-2027. [More Information]
  • Taylor, N., La Hei, E., Karpelowsky, J. (2018). Oesophageal lung. ANZ Journal of Surgery, 88(1-Feb), 108-110. [More Information]
  • Fitzgerald, D., Kench, A., Hatton, L., Karpelowsky, J. (2018). Strategies for improving early nutritional outcomes in children with oesophageal atresia and congenital diaphragmatic hernia. Paediatric Respiratory Reviews, 25, 85-87. [More Information]
  • Vierboom, L., Darani, A., Langusch, C., Soundappan, S., Karpelowsky, J. (2018). Tunnelled central venous access devices in small children: A comparison of open vs. ultrasound-guided percutaneous insertion in children weighing ten kilograms or less. Journal of Pediatric Surgery, 53(9), 1832-1838. [More Information]

2017

  • Nayak, A., McDowell, D., Kellie, S., Karpelowsky, J. (2017). Elevated Preoperative Neutrophil�Lymphocyte Ratio is Predictive of a Poorer Prognosis for Pediatric Patients with Solid Tumors. Annals of Surgical Oncology, 24(11), 3456-3462. [More Information]
  • Read, A., Xu, J., Adams, S., Karpelowsky, J. (2017). Five lessons in uncomplicated appendicitis: Can we remove the surgery? Journal of Paediatrics and Child Health, 53(11), 1127-1130. [More Information]
  • King, S., Karpelowsky, J. (2017). Hirschsprung disease. ANZ Journal of Surgery, 87(10), 754. [More Information]
  • Gluckman, S., Karpelowsky, J., Webster, A., McGee, R. (2017). Management for intussusception in children. Cochrane Database of Systematic Reviews, 2017 (6), 1-54. [More Information]
  • Xu, J., Adams, S., Liu, Y., Karpelowsky, J. (2017). Nonoperative management in children with early acute appendicitis: A systematic review. Journal of Pediatric Surgery, 52(9), 1409-1415. [More Information]
  • Stephenson, C., Norlen, O., Shun, A., Karpelowsky, J., Robinson, B., Delbridge, L. (2017). Papillary thyroid cancer in childhood: is parental screening helpful? ANZ Journal of Surgery, 87(7-8), 615-618. [More Information]
  • Narayanan, S., Cohen, R., Karpelowsky, J. (2017). Patterns of reflux in gastroesophageal reflux disease in pediatric population of New South Wales. Diseases of the Esophagus, 30(2), 1-8. [More Information]
  • Collin, M., Karpelowsky, J., Thomas, G. (2017). Pediatric transplantation: An international perspective. Seminars in Pediatric Surgery, 26(4), 272-277. [More Information]
  • Ziaziaris, W., Darani, A., Holland, A., Alexander, A., Karpelowsky, J., Barbaro, P., Stormon, M., O�Loughlin, E., Shun, A., Thomas, G. (2017). Reducing the incidence of hepatic artery thrombosis in pediatric liver transplantation: Effect of microvascular techniques and a customized anticoagulation protocol. Pediatric Transplantation, 21(4), 1-7. [More Information]

2016

  • Fitzgerald, D., Karpelowsky, J. (2016). "Oesophageal Atresia- We need to be seeing ya!". Paediatric Respiratory Reviews, 19, 1-2. [More Information]
  • Xu, J., Liu, Y., Adams, S., Karpelowsky, J. (2016). Acute uncomplicated appendicitis study: rationale and protocol for a multicentre, prospective randomised controlled non-inferiority study to evaluate the safety and effectiveness of non-operative management in children with acute uncomplicated appendicitis. BMJ Open, 6(12), 1-8. [More Information]
  • Skowno, J., Karpelowsky, J., Watts, N., Little, D. (2016). Can transcutaneous near infrared spectroscopy detect severe hepatic ischemia: a juvenile porcine model. Paediatric Anaesthesia, 26(12), 1188-1196. [More Information]
  • Kamaraj, S., Arbuckle, S., Arbuckle, S., Smith, G., Karpelowsky, J. (2016). Congenital mesoblastic nephroma presenting with hematuria in a neonate: A case report. Urology, 88, 189-191. [More Information]
  • Roberts, K., Karpelowsky, J., Fitzgerald, D., Sannappa Venkatraman, S. (2016). Outcomes of oesophageal atresia and tracheo-oesophageal fistula repair. Journal of Paediatrics and Child Health, 52(7), 694-698. [More Information]
  • Flower, E., Tran, K., Zanjani, S., Smith, W., Karpelowsky, J., Summerhayes, K., Estoesta, E., Chard, J. (2016). Pediatric peri-operative fractionated high-dose-rate brachytherapy for recurrent Wilms' tumor using a reconstructed Freiburg flap. Journal of Contemporary Brachytherapy, 8(5), 429-433. [More Information]
  • Al-lede, M., Karpelowsky, J., Fitzgerald, D. (2016). Recurrent Diaphragmatic Hernia: Modi�?able and Non-Modi�?able Risk Factors. Pediatric Pulmonology, 51(4), 394-401. [More Information]
  • Brown, K., Dunne, B., Festa, M., La Hei, E., Karpelowsky, J., Dando, H., Orr, Y. (2016). Successful 2,000-Kilometer international transfer of an infant receiving extracorporeal membrane oxygenation for severe respiratory failure. The Annals of Thoracic Surgery, 102(2), e131-e133. [More Information]
  • Teague, W., Karpelowsky, J. (2016). Surgical management of oesophageal atresia. Paediatric Respiratory Reviews, 19, 10-15. [More Information]

2015

  • Ziaziaris, W., Darani, A., Holland, A., Alexander, A., Karpelowsky, J., Shun, A., Thomas, G. (2015). Delayed primary closure and the incidence of surgical complications in pediatric liver transplant recipients. Journal of Pediatric Surgery, 50(12), 2137-2140. [More Information]

2014

  • Leeuwen, L., Walker, K., Halliday, R., Karpelowsky, J., Fitzgerald, D. (2014). Growth in children with congenital diaphragmatic hernia during the first year of life. Journal of Pediatric Surgery, 49(9), 1363-1366. [More Information]
  • Skowno, J., Karpelowsky, J. (2014). Near-infrared spectroscopy for monitoring renal transplant perfusion. Pediatric Nephrology, 29(11), 2241-2242. [More Information]

2013

  • Westgarth-Taylor, C., de Lijster, L., van Bogerijen, G., Millar, A., Karpelowsky, J. (2013). A prospective assessment of renal oxygenation in children undergoing laparoscopy using near-infrared spectroscopy. Surgical Endoscopy, 27(10), 3696-3704. [More Information]
  • Wanaguru, D., Shun, A., Price, N., Karpelowsky, J. (2013). Outcomes of pulmonary metastases in hepatoblastoma - is the prognosis always poor? Journal of Pediatric Surgery, 48(12), 2474-2478. [More Information]

2012

  • Karpelowsky, J. (2012). Paediatric Thoracoscopic Surgery. Paediatric Respiratory Reviews, 13(4), 244-251. [More Information]

2009

  • Karpelowsky, J., Thomas, G., Shun, A. (2009). Definitive abdominal wall closure using a porcine intestinal submucosa biodegradable membrane in pediatric transplantation. Pediatric Transplantation, 13(3), 285-289. [More Information]

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