Professor Judy Black

AO
Professor
Pharmacology, School of Medical Sciences
Woolcock Institute of Medical Research

Telephone +61 2 9114 0342
Fax +61 2 9114 0399

Website Related website

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Research interests

Asthma, Pulmonary Fibrosis, Lymphangioleiomyomatosis (LAM), Lung Transplant Medicine, Chronic Obstructive Pulmonary Disease (COPD)

PhD and master's project opportunities

International links

Finland

(University of Helsinki) A study examining the effects of a specific protein discovered in our laboratory in an animal model in the lab of Dr Caroline Heckmann

Italy

(University of Ferrara) a collaborative study between our lab and that of Dr Gaetano Caramori examining receptor abnormalities in smoking induced lung disease

Japan

(Graduate School of Medical Sciences Kyushu University Fukuoka) a recent collaboration combining work on human and animal tissue which has resulted in a publication in a high ranking respiratory journal

New Zealand

(University of Auckland) An ongoing collaboration with Professor Peter Shepherd combining his expertise in PI3 kinase and ours in human airway disease

Switzerland

(University Hospital Basel) Collaborations over the last 10 years with Professor Michael Roth resulting in joint publications and sharing of personnel and students

Selected grants

2014

  • CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Huang M, Scolyer R, Fraser S, Sahni S, Speranza T, Owens T, Barrs V, Ju Y, Kovacevic Z, Lu Z, Camp A, Slobedman B, Morris B, Oliver B, Dos Remedios C, Kalinowski D, Fu D, Lai D, Lovicu F, Allbutt H, Triccas J, Burgess J, Kril J, Dixon K, Rendina L, Byrne M, King N, Groundwater P, Williamson P, Ho J, Dong Q, Bao B, Assinder S, McLennan S, Richardson D, Ammit A, Sharland A, Hardikar A, Hong A, Hambly B, Lee C, Murphy C, Goldsbury C, Johnstone D, Lane D, Hibbs D, Joshua D, Huq F, Halliday G, Sutherland G, Zreiqat H, Lok H, Lyons G, Jansson P, Black J, Zhu L, Sunde M, Day M, Naylor M, Buckland M, Murray M, Shafie N, Lay P, Poronnik P, Codd R, Mason R, Ryan R, Christopherson R, de Graaf S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Richardson D, Kril J, Murphy C, Vandenberg R, Rendina L, Dos Remedios C, Ju Y, Kovacevic Z, Lyons G, Sutherland G, Lay P, Ammit A, Lai D, Morris B, Day M, Dong Q, Bao B, Huang M, Camp A, Boyer M, Whittington R, Byrne M, Hanrahan J, Fu D, Jansson P, Lane D, Bagley E, Hibbs D, Zhang D, Fraser S, Scolyer R, Black J, Halliday G, Christie M, Zreiqat H, Murray M, Slobedman B, Naylor M, Burgess J, Triccas J, Mason R, Chadban S, Combes V, Lovicu F, McLennan S, Kalinowski D, Sharland A, Johnstone D, Groundwater P, Dixon K, Zhou F, Lovejoy D, Lu Z, Zhu L, Goldsbury C, Witting P, Buckland M, Assinder S, Purdie (Williams) A, Codd R, Owens T, Hambly B; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2012

  • GeneAtlas Personal Microarray System; Richardson D, Scolyer R, Stocker R, Weninger W, Black J, Allen D, Murray M, Mason R, Twigg S, King N, Horvath L, Lovicu F, Lee C, Halliday G, Lovejoy D, Joshua D, Sharland A, Roufogalis B, Hambly B, Morris B, Bao B, Bishop A, Hibbs D, Lane D, Zhou F, Hanrahan J, Dixon K, Rendina L, Byrne M, Naylor M, Cole N, Jansson P, Dong Q, Codd R, Payne R, Assinder S, Chadban S, Fraser S, McLennan S, Suryo Rahmanto A, Lai D, Yu Y, Ju Y, Buckland M, Kovacevic Z, Saletta F, Zreiqat H, Kalinowski D, Groundwater P, Simes R, Zhang D, Boyer M, Murphy C; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2011

  • PyroMark Q96 ID system; Richardson D, Stone J, Black J, King N, Mason R, Hunt N, Kril J, Murray M, Scolyer R, Halliday G, Vandenberg R, McMinn P, Chadban S, Byrne M, Ryan R, Dong Q, Lee C, Bishop A, Haass N, Fraser S, Hambly B, Sharland A, Kalinowski D, Assinder S, Yu Y, Bao B, Ju Y, Lovejoy D, Buckland M, Lane D, Dos Remedios C, Kovacevic Z, Sutherland G, Zhang D, Morris B, Suryo Rahmanto A, Murphy C; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Fibulin-a target for lung fibrosis; Black J, Burgess J, Hansbro P; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Lamstatin- a novel inhibitor of lymphangiogenesis; Black J, Weckmann M, Moir L; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Fluorescence attachment and software for Nikon Eclipse Ti-E PFS microscope; Black J; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

2009

  • NHMRC - Senior Principal Research Fellowship; Black J; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.
  • Nikon Eclipse Ti-E PFS research grade inverted microscope and accessories; Black J, Burgess J; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
  • 7-laser BD LSR-II and Cellomics Array Scan VTi to Enhance Capability and Throughput for the NSW Advanced Cytometry Facility; King N, Weninger W, Gunning P, Fazekas de St Groth B, Campbell I, Christopherson R, Black J, Mason R, Richardson D, Halliday G, Grau G, Gandevia S, Kachigian L, Geczy C, Jessup W, Vadas M, Britton W, Hunt N; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Nikon Eclipse Ti-E PFS research grade inverted microscope and accessories; Spence I, Black J; Clive & Vera Ramaciotti Foundation/Awards for Biomedical Research: Major Equipment.

2008

  • Project Details Sub Program 1.4 Mechanisms of Airway Remodelling; Bert P, Black J; CRC FOR ASTHMA AND AIRWAYS LTD/Research Support.
  • Alterations to the lung extracellular matrix induced by the combination of cigarette smoke and respiratory virus infection; Oliver B, Black J; Clive & Vera Ramaciotti Foundation/Equipment Grant.
  • Dako ACIS 111 Cellular Image Acquisition and Analysis System; Hambly B, Bao B, Bishop A, Black J, Campbell I, Dong Q, Gorrell M, Grau G, Hunt N, King N, Markham R, Marsh D, McDonald K, McLennan S, Rodgers K, Seth D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Dako ACIS III Cellular Image Acquisition and Analysis System; Gorrell M, Grau G, Bishop A, Black J, Campbell I, McLennan S, Rodgers K, Seth D, Marsh D, Dong Q, Hambly B, Bao B, King N, Markham R, McDonald K, Hunt N; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Stepone plus 96-well rt pcr system why do viral infections make asthma worse; Black J; Rebecca L Cooper Medical Research Foundation/Research Support.
  • Signal transduction in airway remodelling; Black J, Oliver B, Burgess J; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • Kodak 4000mm Multi-Modal Imaging Station; Black J; Clive & Vera Ramaciotti Foundation/Clive & Vera Ramaciotti Fndtn.
  • Kodak 4000mm Multi-Modal Imaging Station; Black J; Rebecca Cooper Foundation/Rebecca Cooper Foundation.

2006

  • Advanced Imaging Flow Cytometry Facility for NSW; King N, Campbell I, Cook D, Black J, Halliday G, McAvoy J, Gunning P, Pollard J, Murray M, Britton W, Dawes I, Khachigian L, Hunt N; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Rebecca Cooper Medical Research Foundation - Research Grants Program; Black J; Rebecca Cooper Medical Research Foundation/Rebecca Cooper Medical Research Foundation.
  • Testing of Cytokines; Black J, Tso S; Apollo Cytokine Research Pty Ltd/Research Grants.
  • Purchase of an Eppenddorf 5810R centrifuge and adaptors; Black J; Rebecca Cooper Foundation/Equipment Grant.
  • Cellular and mollecular mechanisms of chronic airways disease; Black J; Rebecca Cooper Foundation/Research Grant.

2005

  • Towards a SpectraMax m2 plate reader; Black J; University of Sydney/Equipment Grant.
  • Defining the abnormalities in asthmatic airway smooth muscle; Black J; Rebecca L Cooper/Medical Research Foundation.
  • Parent: CRC Asthma (2006) / # 7611 / CRC for Asthma and Airways, Medical Science and Technology Sec; Hirst T, Cox J, Black J, Fulton G, Dolan N.
  • SpectraMAX M2 plate reader; Black J; Clive & Vera Ramaciotti Foundation/Research Grant.
  • Defining the abnormalities in asthmatic airway smooth muscle; Black J, Burgess J; University of Sydney/Research & Development.
  • Cellular and Molecular mechanisms of chronic airway disease; Black J, Johnson P, Roth M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Project Sub Program 1.4 Mechanisms of Airway Remodelling (includes Project 1.4.1;Project 1.4.2 ; Project 1.4.3); Bert P, Black J; Asthma CRC/Research Grants.
  • FACS Aria for the University of Sydney Flow Cytometry Facility; King N, Pollard J, Rasko J, Lovicu F, Bishop A, Bertolino P, Briscoe H, Gillies M, Madigan M, McAvoy J, Murphy C, Balcar V, Armour C, Hughes M, Reeve V, Christopherson R, Halliday G, Christie M, Pollock C, McCaughan G, Gorrell M, Dong Q, Abendroth A, Menzies S, Barnetson R, Byrne S, Hunt N, Hambly B, Cook D, Mason R, Day M, Black J; University of Sydney/Equipment Grant.

2004

  • Airway remodelling effects of roflumilast; Tenor H, Black J; Altana Pharma Pty Ltd, Germany/BLO Project.
  • Towards an ABI prism 7000 sequence detection system; Johnson P, Black J; DVC Research/Equipment (Sesqui).

2003

  • The airway smooth muscle in asthma-why is it different?; Black J; Anonymous/Project Grant.
  • Towards a multilabel Victor plate reader; Black J; DVC Research/Equipment (Sesqui).
  • Cellular and molecular mechanisms in fibroproliferative lung disease; Johnson P, Burgess J, Black J; Rebecca L Cooper/Medical Research Foundation.
  • 2 x leica microsystems imaging systems; 2 x Computer workstations; Black J, Pollard J, Yue D, McLennan S, Twigg S; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Further studies on beta agonists and corticosteroids; Black J, Roth M; Astra Pharmaceuticals Pty Ltd/Research Support.

2002

  • Studies on mesothelioma; Black J, Roth M; Medical Research and Compensation Foundation/Medical Research.
  • Airway smooth muscle contribution to remodelling in asthma; Johnson P, Roth M, Black J; National Health and Medical Research Council (NHMRC)/Project Grants.

2001

  • Characterisitics of airway smooth muscle in asthma; Black J, Armour C, Johnson P; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Further studies on beta agonist/steroid interactions; Black J, Roth M, Tamm M; Astra Pharmaceuticals Pty Ltd/Research Support.
  • Mechanism of airway remodelling; Black J; Clive & Vera Ramaciotti Foundation/General Grants.
  • Mechanisms of airway remodelling in asthma; Black J, Johnson P; Rebecca L Cooper/Medical Research Foundation.
  • Kodak Image Station 440CF; Black J, Hunt N, Vandenberg R, Johnson P; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Cellular & Molecular Mechanisms in Mesothelioma and Fibroproliferative lung disease; Black J, Roth M; Work Cover NSW [Workers Compensation (Dust Diseases) Board]/Research Grant.

2000

  • Matrix regulation and remodelling in asthmatic airways; Black J, Burgess J; Clive & Vera Ramaciotti Foundation/Research Grant.
  • Identification of genes that are critical for allergic responses; Black J, Hunt N; Australian Research Council (ARC)/Strategic Partnerships with Industry - Research and Training (SPIRT).
  • Cytokines, cells and asthma; Armour C, Hughes M, Black J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Asthma, mast cells and interkleukin 5; Armour C, Schrader A, Hughes M, Black J; Asthma Foundation of NSW/Research Grants.
  • The production of extracellular matrix proteins by human airway smooth muscle in culture- effect of atopic asthmatic allergic serum and corticosteroids; Johnson P, Black J, Armour C; Rebecca L Cooper Medical Research Foundation/Grants Program.

1999

  • Airway hyperresponsiveness in vitro-molecular mechanisms; Black J, Johnson P, Armour C; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.

Selected publications

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Book Chapters

  • Black, J., Burgess, J., Oliver, B., Moir, L. (2008). Altered properties of airway smooth muscle in asthma. In Chung, K. (Eds.), Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology, (pp. 181-199). United Kingdom: John Wiley & Sons.
  • Roth, M., Black, J. (2007). Altered transcription factors in airway smooth muscle. In Jean-Pierre Savineau (Eds.), New Frontiers in Smooth Muscle Biology and Physiology 2007, (pp. 431-455). Kerala, India: Transworld Research Network.
  • Roth, M., Black, J. (2007). The role of transcription factors in asthma: can we modify them for therapeutic purposes? In Riccardo Polosa and Stephen T Holgate (Eds.), Asthma: Modern Therapeutic Targets, (pp. 33-47). Oxford: Clinical Publishing, Oxford.

Journals

  • Banville, N., Burgess, J., Jaffar, J., Tjin, G., Richeldi, L., Cerri, S., Persiani, E., Black, J., Oliver, B. (2014). A Quantitative Proteomic Approach to Identify Significantly Altered Protein Networks in the Serum of Patients with Lymphangioleiomyomatosis (LAM). PLoS One, 9(8), e105365. [More Information]
  • Chen, L., Ge, Q., Tjin, G., Alkhouri, H., Deng, L., Brandsma, C., Adcock, I., Timens, W., Postma, D., Burgess, J., Black, J., Oliver, B. (2014). Effects of cigarette smoke extract on human airway smooth muscle cells in COPD. The European Respiratory Journal, 44(3), 636-646. [More Information]
  • Grafton, K., Moir, L., Black, J., Hansbro, N., Hansbro, P., Burgess, J., Oliver, B. (2014). LF-15 and T7, Synthetic Peptides Derived from Tumstatin, Attenuate Aspects of Airway Remodelling in a Murine Model of Chronic OVA-Induced Allergic Airway Disease. PLoS One, 9(1), 1-6. [More Information]
  • Van Ly, D., Faiz, A., Jenkins, C., Crossett, B., Black, J., McParland, B., Burgess, J., Oliver, B. (2013). Characterising the Mechanism of Airway Smooth Muscle B2 Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells. PLoS One, 8(2), 1-17. [More Information]
  • Chen, L., Ge, Q., Black, J., Deng, L., Burgess, J., Oliver, B. (2013). Differential Regulation of Extracellular Matrix and Soluble Fibulin-1 Levels by TGF-β1 in Airway Smooth Muscle Cells. PLoS One, 8(6), 1-8. [More Information]
  • Krimmer, D., Ichimaru, Y., Burgess, J., Black, J., Oliver, B. (2013). Exposure to Biomass Smoke Extract Enhances Fibronectin Release from Fibroblasts. PLoS One, 8(12), 1-10. [More Information]
  • Van Ly, D., De Pedro, M., James, P., Morgan, L., Black, J., Burgess, J., Oliver, B. (2013). Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle. Respiratory Research (Online), 14(127), 1-11. [More Information]
  • Faiz, A., Tjin, G., Harkness, L., Weckmann, M., Bao, B., Black, J., Oliver, B., Burgess, J. (2013). The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways. PLoS One, 8(3), 1-8. [More Information]
  • Black, J., Panettieri, R., Banerjee, A., Berger, P. (2012). Airway Smooth Muscle in Asthma: Just a Target for Bronchodilation? Clinics in Chest Medicine, 33(3), 543-558. [More Information]
  • Niimi, K., Ge, Q., Moir, L., Ammit, A., Trian, T., Burgess, J., Black, J., Oliver, B. (2012). B2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers. American Journal of Physiology: Lung Cellular and Molecular Physiology, 302(3), L334-L342. [More Information]
  • Ge, Q., Poniris, M., Moir, L., Black, J., Burgess, J. (2012). Combined Beta-Agonists and Corticosteroids Do Not Inhibit Extracellular Matrix Protein Production In Vitro. Journal of Allergy, 2012, 1-7. [More Information]
  • Bosse, Y., Vagula, M., Pun, M., Black, J., Berger, P., Rawding, R., Burgess, J., Adner, M., Oliver, B., Marthan, R. (2012). Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma. Journal of Applied Physiology, 113(5), 844-846. [More Information]
  • Baraket, M., Oliver, B., Burgess, J., Lim, S., King, G., Black, J. (2012). Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. Respiratory Research (Online), 13(2 February 2012), 1-11. [More Information]
  • Weckmann, M., Moir, L., Heckman, C., Black, J., Oliver, B., Burgess, J. (2012). Lamstatin - a novel inhibitor of lymphangiogenesis derived from collagen IV. Journal of Cellular and Molecular Medicine, 16(12), 3062-3073. [More Information]
  • Krimmer, D., Burgess, J., Wooi, T., Black, J., Oliver, B. (2012). Matrix Proteins from Smoke Exposed Fibroblasts are Pro-proliferative. American Journal of Respiratory Cell and Molecular Biology, 46(1), 34-39. [More Information]
  • Van Ly, D., Burgess, J., Brock, T., Lee, T., Black, J., Oliver, B. (2012). Prostaglandins but not leukotrienes alter extracellular matrix protein deposition and cytokine release in primary human airway smooth muscle cells and fibroblasts. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(3), L239-L250. [More Information]
  • Ichimaru, Y., Krimmer, D., Burgess, J., Black, J., Oliver, B. (2012). TGF-B enhances deposition of perlecan from COPD airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 302(3), L325-L333. [More Information]
  • Ge, Q., Moir, L., Trian, T., Niimi, K., Poniris, M., Shepherd, P., Black, J., Oliver, B., Burgess, J. (2012). The phosphoinositide 3'-kinase p110d modulates contractile protein production and IL-6 release in human airway smooth muscle. Journal of Cellular Physiology, 227(8), 3044-3052. [More Information]
  • Moir, L., Black, J., Krymskaya, V. (2012). TSC2 modulates cell adhesion and migration via integrin-a1B1. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(8), L703-L710. [More Information]
  • Moir, L., Ng, H., Poniris, M., Santa, T., Burgess, J., Oliver, B., Krymskaya, V., Black, J. (2011). Doxycycline inhibits matrix metalloproteinase-2 secretion from TSC2-null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells. British Journal of Pharmacology, 164(1), 83-92. [More Information]
  • Van Ly, D., King, N., Moir, L., Burgess, J., Black, J., Oliver, B. (2011). Effects of β2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts. Journal of Allergy, 2011 (Article ID 457169), 1-11. [More Information]
  • Moir, L., Trian, T., Ge, Q., Shepherd, P., Burgess, J., Oliver, B., Black, J. (2011). Phosphatidylinositol 3-Kinase Isoform-Specific Effects in Airway Mesenchymal Cell Function. Journal of Pharmacology and Experimental Therapeutics, 337(2), 557-566. [More Information]
  • Kuo, C., Lim, S., King, N., Bartlett, N., Walton, R., Zhu, J., Glanville, N., Aniscenko, J., Johnston, S., Burgess, J., Black, J., Oliver, B. (2011). Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo. Respirology, 16(2), 367-377. [More Information]
  • Kuo, C., Lim, S., King, N., Johnston, S., Burgess, J., Black, J., Oliver, B. (2011). Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 300(6), L951-L957. [More Information]
  • Trian, T., Burgess, J., Niimi, K., Moir, L., Ge, Q., Berger, P., Liggett, S., Black, J., Oliver, B. (2011). β(2)-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D. PLoS One, 6(5), e20000-1-e20000-7. [More Information]
  • Lau, J., Oliver, B., Moir, L., Black, J., Burgess, J. (2010). Differential expression of peroxisome proliferator activated receptor gamma and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells. Respirology, 15(2), 303-312. [More Information]
  • Lau, J., Oliver, B., Baraket, M., Beckett, E., Hansbro, N., Moir, L., Wilton, S., Williams, C., Foster, P., Hansbro, P., Black, J., Burgess, J. (2010). Fibulin-1 is increased in asthma - a novel mediator of airway remodeling? PLoS One, 5(10 (e13360)), 1-13. [More Information]
  • Burgess, J., Boustany, S., Moir, L., Weckmann, M., Lau, J., Grafton, K., Baraket, M., Hansbro, P., Hansbro, N., Foster, P., Black, J., Oliver, B. (2010). Reduction of Tumstatin in Asthmatic Airways Contributes to Angiogenesis, Inflammation and Hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine, 181(2), 106-115. [More Information]
  • Ge, Q., Moir, L., Black, J., Oliver, B., Burgess, J. (2010). TGFBeta1 Induces IL-6 and Inhibits IL-8 Release in Human Bronchial Epithelial Cells: The Role of Smad2/3. Journal of Cellular Physiology, 225(3), 846-854. [More Information]
  • Roth, M., Black, J. (2009). An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy? British Journal of Pharmacology, 157(3), 334-341. [More Information]
  • Krimmer, D., Loseli, M., Hughes, M., Oliver, B., Moir, L., Hunt, N., Black, J., Burgess, J. (2009). CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle. Allergy, 64, 1074-1082. [More Information]
  • Klagas, I., Goulet, S., Karakiulakis, G., Zhong, J., Baraket, M., Black, J., Papakonstantinou, E., Roth, M. (2009). Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD. European Respiratory Journal, 34(3), 616-628. [More Information]
  • Borger, P., Miglino, N., Baraket, M., Black, J., Tamm, M., Roth, M. (2009). Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients. Journal of Allergy and Clinical Immunology, 123(3), 639-645. [More Information]
  • Black, J., Roth, M. (2009). Intrinsic asthma: is it intrinsic to the smooth muscle? Clinical and Experimental Allergy, 39(7), 962-965. [More Information]
  • Black, J., Oliver, B., Roth, M. (2009). Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists. Chest, 136(4), 1095-1100. [More Information]
  • Fukuyama, S., Nakano, T., Matsumoto, T., Oliver, B., Burgess, J., Moriwaki, A., Tanaka, K., Kubo, M., Hoshino, T., Tanaka, H., Black, J., et al (2009). Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype. American Journal of Respiratory and Critical Care Medicine, 179(11), 992-998. [More Information]
  • Trian, T., Qi, G., Moir, L., Burgess, J., Kuo, C., King, N., Reddel, H., Black, J., Oliver, B., McParland, B. (2009). Rhinovirus-induced Exacerbations of Asthma - How is the β2-adrenoceptor Implicated? American Journal of Respiratory Cell and Molecular Biology, 43(2), 227-233. [More Information]
  • Hostettler, K., Roth, M., Burgess, J., Gencay, M., Gambazzi, F., Black, J., Tamm, M., Borger, P. (2008). Airway epithelium-derived transforming growth factor-beta is a regulator of fibroblast proliferation in both fibrotic and normal subjects. Clinical and Experimental Allergy, 38(8), 1309-1317. [More Information]
  • Burgess, J., Lee, J., Ge, Q., Ramsay, E., Poniris, M., Parmentier, J., Roth, M., Johnson, P., Hunt, N., Black, J., Ammit, A. (2008). Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma. Journal of Cellular Physiology, 216(3), 673-679. [More Information]
  • Oliver, B., Lim, S., Wark, P., Laza-Stanca, V., King, N., Black, J., Burgess, J., Roth, M., Johnston, S. (2008). Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages. Thorax, 63(6), 519-525. [More Information]
  • Moir, L., Burgess, J., Black, J. (2008). Transforming growth factor β1 increases fibronectin deposition through integrin receptor α5β1 on human airway smooth muscle. Journal of Allergy and Clinical Immunology, 121(4), 1034-1039. [More Information]
  • An, S., Bai, T., Bates, J., Black, J., Brown, R., Brusasco, V., Chitano, P., Deng, L., King, G., McParland, B., et al (2007). Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. European Respiratory Journal, 29(5), 834-860. [More Information]
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. Thorax, 62(10), 848-854. [More Information]
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by asthmatic and non-asthmatic airway smooth muscle cells. Thorax, 62(10), 848-854. [More Information]
  • Borger, P., Matsumoto, H., Boustany, S., Gencay, M., Burgess, J., King, G., Black, J., Tamm, M., Roth, M. (2007). Disease-specific expression and regulation of CCAAT/enhancer-binding proteins in asthma and chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology. [More Information]
  • Burgess, J., Oliver, B., Poniris, M., Ge, Q., Boustany, S., Cox, N., Moir, L., Johnson, P., Black, J. (2006). A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro. Journal of Allergy and Clinical Immunology, 118(3), 649-657. [More Information]
  • Oliver, B., Black, J. (2006). Airway smooth muscle and asthma. Allergology International, 55(3), 215-223. [More Information]
  • Borger, P., Tamm, M., Black, J., Roth, M. (2006). Asthma: Is it due to an abnormal airway smooth muscle cell? American Journal of Respiratory and Critical Care Medicine, 174(4), 367-372.
  • Burgess, J., Ge, Q., Poniris, M., Boustany, S., Twigg, S., Black, J., Johnson, P. (2006). Connective tissue growth factor and vascular endothelial growth factor from airway smooth muscle interact with the extracellular matrix. American Journal of Physiology: Lung Cellular and Molecular Physiology, 290(1), L153-L161. [More Information]
  • Johnson, P., Burgess, J., Ge, Q., Poniris, M., Boustany, S., Twigg, S., Black, J. (2006). Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. American Journal of Respiratory and Critical Care Medicine, 173(1), 32-41. [More Information]
  • Zhong, J., Gencay, M., Bubendorf, L., Burgess, J., Parsons, H., Robinson, B., Tamm, M., Black, J., Roth, M. (2006). ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells. Journal of Cellular Physiology, 207(2), 540-552. [More Information]
  • Oliver, B., Johnston, S., Baraket, M., Burgess, J., King, N., Roth, M., Lim, S., Black, J. (2006). Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respiratory Research, 7, 71-71. [More Information]
  • Ammit, A., Moir, L., Oliver, B., Hughes, M., Alkhouri, H., Ge, Q., Burgess, J., Black, J., Roth, M. (2006). The effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 292(1), L199-L206. [More Information]
  • Roth, M., Black, J. (2006). Transcription factors in asthma: Are transcription factors a new target for asthma therapy? Current Drug Targets, 7(5), 589-595.
  • Burgess, J., Blake, A., Boustany, S., Johnson, P., Armour, C., Black, J., Hunt, N., Hughes, M. (2005). CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. Journal of Allergy and Clinical Immunology, 115(2), 302-308. [More Information]
  • Black, J., Ge, Q., Boustany, S., Johnson, P., Poniris, M., Glanville, A., Oliver, B., Moir, L., Burgess, J. (2005). In vitro studies of lymphangioleiomyomatosis. European Respiratory Journal, 26(4), 569-576. [More Information]
  • Brightling, C., Ammit, A., Kaur, D., Black, J., Wardlaw, A., Hughes, M., Bradding, P. (2005). The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle. American Journal of Respiratory and Critical Care Medicine, 171(10), 1103-1108. [More Information]
  • McParland, B., Pare, P., Johnson, P., Armour, C., Black, J. (2004). Airway Basement Membrane Perimeter In Human Airways Is Not A Constant; Potential Implications For Airway Remodeling In Asthma. Journal of Applied Physiology, 97(2), 556-563.
  • Hostettler, K., Roth, M., Burgess, J., Johnson, P., Glanville, A., Tamm, M., Black, J., Borger, P. (2004). Cyclosporine A Mediates Fibroproliferation Through Epithelial Cells. Transplantation, 77(12), 1886-1893.
  • Burgess, J., Carlin, S., Pack, R., Arndt, G., Au, W., Black, J., Johnson, P., Hunt, N. (2004). Detection And Characterization Of Ox40 Ligand Expression In Human Airway Smooth Muscle Cells: A Possible Role In Asthma? Journal of Allergy and Clinical Immunology, 113(4), 683-9. [More Information]
  • Roth, M., Johnson, P., Borger, P., Bihl, M., Rudiger, J., King, G., Ge, Q., Hostettler, K., Burgess, J., Black, J., et al (2004). Dysfunctional Interaction Of C/EBPα And The Glucocorticoid Receptor In Asthmatic Bronchial Smooth-Muscle Cells. New England Journal of Medicine, 351(6), 560-574.
  • Azzola, A., Black, J., Chhajed, P., Roth, M., Johnson, P., Havryk, A., Hostettler, K., Granville, A., Tamm, M. (2004). Everolimus And Mycophenolate Mofetil Are Potent Inhibitors Of Fibroblast Proliferation After Lung Transplantation. Transplantation, 77(2), 275-280.
  • Johnson, P., Burgess, J., Underwood, A., Au, W., Poniris, M., Tamm, M., Ge, Q., Roth, M., Black, J. (2004). Extracellular Matrix Proteins Modulate Asthmatic Airway Smooth Muscle Cell Proliferation Via An Autocrine Mechanism. Journal of Allergy and Clinical Immunology, 113(4), 690-6. [More Information]
  • Burgess, J., Ge, Q., Boustany, S., Black, J., Johnson, P. (2004). Increased Sensitivity Of Asthmatic Airway Smooth Muscle Cells To Prostaglandin E2 Might Be Mediated By Increased Numbers Of E-Prostanoid Receptors. Journal of Allergy and Clinical Immunology, 113(5), 876-881. [More Information]
  • Merrilees, M., Hankin, E., Black, J., Beaumont, B. (2004). Matrix Proteoglycans And Remodelling Of Interstitial Lung Tissue In Lymphangioleiomyomatosis. Journal of Pathology, 203(2), 653-660. [More Information]
  • Black, J., Burgess, J., Johnson, P. (2003). Airway smooth muscle - its relationship to the extracellular matrix. Respiratory Physiology and Neurobiology, 137(2-3), 339-346.
  • Burgess, J., Johnson, P., Ge, Q., Au, W., Poniris, M., McParland, B., King, G., Roth, M., Black, J. (2003). Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 167(1), 71-77.
  • McClean, M., Matheson, M., McKay, K., Johnson, P., Rynell, A., Ammit, A., Black, J., Berend, N. (2003). Low lung volume alters contractile properties of airway smooth muscle in sheep. European Respiratory Journal, 22(1), 50-56.
  • Chambers, L., Black, J., Ge, Q., Carlin, S., Au, W., Poniris, M., Thompson, J., Johnson, P., Burgess, J. (2003). PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 285(3), L619-L627.
  • Carlin, S., Roth, M., Black, J. (2003). Urokinase potentiates PDGF-induced chemotaxis of human airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 284(6), L1020-L1026.
  • Borger, P., Black, J., Roth, M. (2002). Asthma and the CCAAT-enhancer binding proteins: A holistic view on airway inflammation and remodeling. Journal of Allergy and Clinical Immunology, 110(6), 841-846.
  • Black, J., Johnson, P. (2002). Factors controlling smooth muscle proliferation and airway remodelling. Current Opinion in Allergy and Clinical Immunology, , 47-51.
  • Roth, M., Johnson, P., Rudiger, J., King, G., Ge, Q., Burgess, J., Anderson, G., Tamm, M., Black, J. (2002). Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. The Lancet, 360(9342), 1293-1299.
  • Johnson, P., Roth, M., Tamm, M., Hughes, M., Ge, Q., King,, G., Burgess, J., Black, J. (2001). Airway smooth muscle cell proliferation is increased in asthma. American Journal of Respiratory and Critical Care Medicine, 164(3), 474-477.
  • Black, J., Armour, C., Tamm, M., Roth, M., Johnson, P. (2001). Airway Wall remodelling-the role of the smooth muscle. Clinical and Experimental Allergy, 1(2), 116-119.
  • Lee, J., Johnson, P., Roth, M., Hunt, N., Black, J. (2001). ERK activation and mitogenesis in human airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 280.
  • Black, J., Johnson, P., Armour, C. (2001). Factors controlling transduction signaling and proliferation of airway smooth muscle. Current Allergy and Asthma Reports, 1, 116-121.
  • Chambers, L., Black, J., Poronnik, P., Johnson, P. (2001). Functional effects of protease-activated receptor-2 stimulation on human airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281.
  • Page, S., Ammit, A., Black, J., Armour, C. (2001). Human mast cell and airway smooth muscle cell interactions: implications for asthma. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281(6, Pt1), L1313-L1323.
  • Black, J., Roth, M., Lee, J., Carlin, S., Johnson, P. (2001). Mechanisms of airway remodelling. American Journal of Respiratory and Critical Care Medicine, 164.
  • Tamm, M., Roth, M., Johnson, P., Black, J., Malouf, M., Chhajed, P., Glanville, A. (2001). Primary fibroblast cell cultures from transbronchial biopsies of lung transplant recipients. Transplantation, 71, 337-339.
  • McKay, K., Johnson, P., Black, J., Armour, C. (2000). Parasympathetic neurotransmission in rabbit isolatedbronchus is modulated at prejunctional sites via endothelinB receptor stimulation. Respirology, 5, 343-353.

Conferences

  • Page, S., Black, J., Armour, C., Ammit, A., Poulton, S., Speigel, S. (2002). Human lung mast cells as a possible source of sphingosine 1-phosphate (SPP) in asthma. International Conference of the American Thoracic Society, : British Medical Journal Publishing Group.
  • Ammit, A., Black, J., McClean, M., Matheson, M., Berend, N. (2002). MLCK content of tracheal and bronchial smooth muscle in sheep and rabbits. The Thoracic Society of Australia and New Zealand Annual Scientific meeting, 54 University St,P O Box 378, Carlton, Australia, 3053: Blackwell Publishers.

Patents

  • Oliver, B., Black, J., Burgess, J., Boustany, S. (2012). Method for Modulating Cellular Activity and Agents for use therein (Tumstatin) - Asthma CRC. Patent No. 1988915, 8227419. France, Germany, Switzerland, United Kingdom.

2014

  • Banville, N., Burgess, J., Jaffar, J., Tjin, G., Richeldi, L., Cerri, S., Persiani, E., Black, J., Oliver, B. (2014). A Quantitative Proteomic Approach to Identify Significantly Altered Protein Networks in the Serum of Patients with Lymphangioleiomyomatosis (LAM). PLoS One, 9(8), e105365. [More Information]
  • Chen, L., Ge, Q., Tjin, G., Alkhouri, H., Deng, L., Brandsma, C., Adcock, I., Timens, W., Postma, D., Burgess, J., Black, J., Oliver, B. (2014). Effects of cigarette smoke extract on human airway smooth muscle cells in COPD. The European Respiratory Journal, 44(3), 636-646. [More Information]
  • Grafton, K., Moir, L., Black, J., Hansbro, N., Hansbro, P., Burgess, J., Oliver, B. (2014). LF-15 and T7, Synthetic Peptides Derived from Tumstatin, Attenuate Aspects of Airway Remodelling in a Murine Model of Chronic OVA-Induced Allergic Airway Disease. PLoS One, 9(1), 1-6. [More Information]

2013

  • Van Ly, D., Faiz, A., Jenkins, C., Crossett, B., Black, J., McParland, B., Burgess, J., Oliver, B. (2013). Characterising the Mechanism of Airway Smooth Muscle B2 Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells. PLoS One, 8(2), 1-17. [More Information]
  • Chen, L., Ge, Q., Black, J., Deng, L., Burgess, J., Oliver, B. (2013). Differential Regulation of Extracellular Matrix and Soluble Fibulin-1 Levels by TGF-β1 in Airway Smooth Muscle Cells. PLoS One, 8(6), 1-8. [More Information]
  • Krimmer, D., Ichimaru, Y., Burgess, J., Black, J., Oliver, B. (2013). Exposure to Biomass Smoke Extract Enhances Fibronectin Release from Fibroblasts. PLoS One, 8(12), 1-10. [More Information]
  • Van Ly, D., De Pedro, M., James, P., Morgan, L., Black, J., Burgess, J., Oliver, B. (2013). Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle. Respiratory Research (Online), 14(127), 1-11. [More Information]
  • Faiz, A., Tjin, G., Harkness, L., Weckmann, M., Bao, B., Black, J., Oliver, B., Burgess, J. (2013). The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways. PLoS One, 8(3), 1-8. [More Information]

2012

  • Black, J., Panettieri, R., Banerjee, A., Berger, P. (2012). Airway Smooth Muscle in Asthma: Just a Target for Bronchodilation? Clinics in Chest Medicine, 33(3), 543-558. [More Information]
  • Niimi, K., Ge, Q., Moir, L., Ammit, A., Trian, T., Burgess, J., Black, J., Oliver, B. (2012). B2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers. American Journal of Physiology: Lung Cellular and Molecular Physiology, 302(3), L334-L342. [More Information]
  • Ge, Q., Poniris, M., Moir, L., Black, J., Burgess, J. (2012). Combined Beta-Agonists and Corticosteroids Do Not Inhibit Extracellular Matrix Protein Production In Vitro. Journal of Allergy, 2012, 1-7. [More Information]
  • Bosse, Y., Vagula, M., Pun, M., Black, J., Berger, P., Rawding, R., Burgess, J., Adner, M., Oliver, B., Marthan, R. (2012). Comments on Point:Counterpoint: Alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma. Journal of Applied Physiology, 113(5), 844-846. [More Information]
  • Baraket, M., Oliver, B., Burgess, J., Lim, S., King, G., Black, J. (2012). Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. Respiratory Research (Online), 13(2 February 2012), 1-11. [More Information]
  • Weckmann, M., Moir, L., Heckman, C., Black, J., Oliver, B., Burgess, J. (2012). Lamstatin - a novel inhibitor of lymphangiogenesis derived from collagen IV. Journal of Cellular and Molecular Medicine, 16(12), 3062-3073. [More Information]
  • Krimmer, D., Burgess, J., Wooi, T., Black, J., Oliver, B. (2012). Matrix Proteins from Smoke Exposed Fibroblasts are Pro-proliferative. American Journal of Respiratory Cell and Molecular Biology, 46(1), 34-39. [More Information]
  • Oliver, B., Black, J., Burgess, J., Boustany, S. (2012). Method for Modulating Cellular Activity and Agents for use therein (Tumstatin) - Asthma CRC. Patent No. 1988915, 8227419. France, Germany, Switzerland, United Kingdom.
  • Van Ly, D., Burgess, J., Brock, T., Lee, T., Black, J., Oliver, B. (2012). Prostaglandins but not leukotrienes alter extracellular matrix protein deposition and cytokine release in primary human airway smooth muscle cells and fibroblasts. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(3), L239-L250. [More Information]
  • Ichimaru, Y., Krimmer, D., Burgess, J., Black, J., Oliver, B. (2012). TGF-B enhances deposition of perlecan from COPD airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 302(3), L325-L333. [More Information]
  • Ge, Q., Moir, L., Trian, T., Niimi, K., Poniris, M., Shepherd, P., Black, J., Oliver, B., Burgess, J. (2012). The phosphoinositide 3'-kinase p110d modulates contractile protein production and IL-6 release in human airway smooth muscle. Journal of Cellular Physiology, 227(8), 3044-3052. [More Information]
  • Moir, L., Black, J., Krymskaya, V. (2012). TSC2 modulates cell adhesion and migration via integrin-a1B1. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(8), L703-L710. [More Information]

2011

  • Moir, L., Ng, H., Poniris, M., Santa, T., Burgess, J., Oliver, B., Krymskaya, V., Black, J. (2011). Doxycycline inhibits matrix metalloproteinase-2 secretion from TSC2-null mouse embryonic fibroblasts and lymphangioleiomyomatosis cells. British Journal of Pharmacology, 164(1), 83-92. [More Information]
  • Van Ly, D., King, N., Moir, L., Burgess, J., Black, J., Oliver, B. (2011). Effects of β2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts. Journal of Allergy, 2011 (Article ID 457169), 1-11. [More Information]
  • Moir, L., Trian, T., Ge, Q., Shepherd, P., Burgess, J., Oliver, B., Black, J. (2011). Phosphatidylinositol 3-Kinase Isoform-Specific Effects in Airway Mesenchymal Cell Function. Journal of Pharmacology and Experimental Therapeutics, 337(2), 557-566. [More Information]
  • Kuo, C., Lim, S., King, N., Bartlett, N., Walton, R., Zhu, J., Glanville, N., Aniscenko, J., Johnston, S., Burgess, J., Black, J., Oliver, B. (2011). Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo. Respirology, 16(2), 367-377. [More Information]
  • Kuo, C., Lim, S., King, N., Johnston, S., Burgess, J., Black, J., Oliver, B. (2011). Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 300(6), L951-L957. [More Information]
  • Trian, T., Burgess, J., Niimi, K., Moir, L., Ge, Q., Berger, P., Liggett, S., Black, J., Oliver, B. (2011). β(2)-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D. PLoS One, 6(5), e20000-1-e20000-7. [More Information]

2010

  • Lau, J., Oliver, B., Moir, L., Black, J., Burgess, J. (2010). Differential expression of peroxisome proliferator activated receptor gamma and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells. Respirology, 15(2), 303-312. [More Information]
  • Lau, J., Oliver, B., Baraket, M., Beckett, E., Hansbro, N., Moir, L., Wilton, S., Williams, C., Foster, P., Hansbro, P., Black, J., Burgess, J. (2010). Fibulin-1 is increased in asthma - a novel mediator of airway remodeling? PLoS One, 5(10 (e13360)), 1-13. [More Information]
  • Burgess, J., Boustany, S., Moir, L., Weckmann, M., Lau, J., Grafton, K., Baraket, M., Hansbro, P., Hansbro, N., Foster, P., Black, J., Oliver, B. (2010). Reduction of Tumstatin in Asthmatic Airways Contributes to Angiogenesis, Inflammation and Hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine, 181(2), 106-115. [More Information]
  • Ge, Q., Moir, L., Black, J., Oliver, B., Burgess, J. (2010). TGFBeta1 Induces IL-6 and Inhibits IL-8 Release in Human Bronchial Epithelial Cells: The Role of Smad2/3. Journal of Cellular Physiology, 225(3), 846-854. [More Information]

2009

  • Roth, M., Black, J. (2009). An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy? British Journal of Pharmacology, 157(3), 334-341. [More Information]
  • Krimmer, D., Loseli, M., Hughes, M., Oliver, B., Moir, L., Hunt, N., Black, J., Burgess, J. (2009). CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle. Allergy, 64, 1074-1082. [More Information]
  • Klagas, I., Goulet, S., Karakiulakis, G., Zhong, J., Baraket, M., Black, J., Papakonstantinou, E., Roth, M. (2009). Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD. European Respiratory Journal, 34(3), 616-628. [More Information]
  • Borger, P., Miglino, N., Baraket, M., Black, J., Tamm, M., Roth, M. (2009). Impaired translation of CCAAT/enhancer binding protein alpha mRNA in bronchial smooth muscle cells of asthmatic patients. Journal of Allergy and Clinical Immunology, 123(3), 639-645. [More Information]
  • Black, J., Roth, M. (2009). Intrinsic asthma: is it intrinsic to the smooth muscle? Clinical and Experimental Allergy, 39(7), 962-965. [More Information]
  • Black, J., Oliver, B., Roth, M. (2009). Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists. Chest, 136(4), 1095-1100. [More Information]
  • Fukuyama, S., Nakano, T., Matsumoto, T., Oliver, B., Burgess, J., Moriwaki, A., Tanaka, K., Kubo, M., Hoshino, T., Tanaka, H., Black, J., et al (2009). Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype. American Journal of Respiratory and Critical Care Medicine, 179(11), 992-998. [More Information]
  • Trian, T., Qi, G., Moir, L., Burgess, J., Kuo, C., King, N., Reddel, H., Black, J., Oliver, B., McParland, B. (2009). Rhinovirus-induced Exacerbations of Asthma - How is the β2-adrenoceptor Implicated? American Journal of Respiratory Cell and Molecular Biology, 43(2), 227-233. [More Information]

2008

  • Hostettler, K., Roth, M., Burgess, J., Gencay, M., Gambazzi, F., Black, J., Tamm, M., Borger, P. (2008). Airway epithelium-derived transforming growth factor-beta is a regulator of fibroblast proliferation in both fibrotic and normal subjects. Clinical and Experimental Allergy, 38(8), 1309-1317. [More Information]
  • Black, J., Burgess, J., Oliver, B., Moir, L. (2008). Altered properties of airway smooth muscle in asthma. In Chung, K. (Eds.), Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology, (pp. 181-199). United Kingdom: John Wiley & Sons.
  • Burgess, J., Lee, J., Ge, Q., Ramsay, E., Poniris, M., Parmentier, J., Roth, M., Johnson, P., Hunt, N., Black, J., Ammit, A. (2008). Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma. Journal of Cellular Physiology, 216(3), 673-679. [More Information]
  • Oliver, B., Lim, S., Wark, P., Laza-Stanca, V., King, N., Black, J., Burgess, J., Roth, M., Johnston, S. (2008). Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages. Thorax, 63(6), 519-525. [More Information]
  • Moir, L., Burgess, J., Black, J. (2008). Transforming growth factor β1 increases fibronectin deposition through integrin receptor α5β1 on human airway smooth muscle. Journal of Allergy and Clinical Immunology, 121(4), 1034-1039. [More Information]

2007

  • An, S., Bai, T., Bates, J., Black, J., Brown, R., Brusasco, V., Chitano, P., Deng, L., King, G., McParland, B., et al (2007). Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. European Respiratory Journal, 29(5), 834-860. [More Information]
  • Roth, M., Black, J. (2007). Altered transcription factors in airway smooth muscle. In Jean-Pierre Savineau (Eds.), New Frontiers in Smooth Muscle Biology and Physiology 2007, (pp. 431-455). Kerala, India: Transworld Research Network.
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. Thorax, 62(10), 848-854. [More Information]
  • Matsumoto, H., Moir, L., Oliver, B., Burgess, J., Roth, M., Black, J., McParland, B. (2007). Comparison of gel contraction mediated by asthmatic and non-asthmatic airway smooth muscle cells. Thorax, 62(10), 848-854. [More Information]
  • Borger, P., Matsumoto, H., Boustany, S., Gencay, M., Burgess, J., King, G., Black, J., Tamm, M., Roth, M. (2007). Disease-specific expression and regulation of CCAAT/enhancer-binding proteins in asthma and chronic obstructive pulmonary disease. Journal of Allergy and Clinical Immunology. [More Information]
  • Roth, M., Black, J. (2007). The role of transcription factors in asthma: can we modify them for therapeutic purposes? In Riccardo Polosa and Stephen T Holgate (Eds.), Asthma: Modern Therapeutic Targets, (pp. 33-47). Oxford: Clinical Publishing, Oxford.

2006

  • Burgess, J., Oliver, B., Poniris, M., Ge, Q., Boustany, S., Cox, N., Moir, L., Johnson, P., Black, J. (2006). A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro. Journal of Allergy and Clinical Immunology, 118(3), 649-657. [More Information]
  • Oliver, B., Black, J. (2006). Airway smooth muscle and asthma. Allergology International, 55(3), 215-223. [More Information]
  • Borger, P., Tamm, M., Black, J., Roth, M. (2006). Asthma: Is it due to an abnormal airway smooth muscle cell? American Journal of Respiratory and Critical Care Medicine, 174(4), 367-372.
  • Burgess, J., Ge, Q., Poniris, M., Boustany, S., Twigg, S., Black, J., Johnson, P. (2006). Connective tissue growth factor and vascular endothelial growth factor from airway smooth muscle interact with the extracellular matrix. American Journal of Physiology: Lung Cellular and Molecular Physiology, 290(1), L153-L161. [More Information]
  • Johnson, P., Burgess, J., Ge, Q., Poniris, M., Boustany, S., Twigg, S., Black, J. (2006). Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. American Journal of Respiratory and Critical Care Medicine, 173(1), 32-41. [More Information]
  • Zhong, J., Gencay, M., Bubendorf, L., Burgess, J., Parsons, H., Robinson, B., Tamm, M., Black, J., Roth, M. (2006). ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells. Journal of Cellular Physiology, 207(2), 540-552. [More Information]
  • Oliver, B., Johnston, S., Baraket, M., Burgess, J., King, N., Roth, M., Lim, S., Black, J. (2006). Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respiratory Research, 7, 71-71. [More Information]
  • Ammit, A., Moir, L., Oliver, B., Hughes, M., Alkhouri, H., Ge, Q., Burgess, J., Black, J., Roth, M. (2006). The effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 292(1), L199-L206. [More Information]
  • Roth, M., Black, J. (2006). Transcription factors in asthma: Are transcription factors a new target for asthma therapy? Current Drug Targets, 7(5), 589-595.

2005

  • Burgess, J., Blake, A., Boustany, S., Johnson, P., Armour, C., Black, J., Hunt, N., Hughes, M. (2005). CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. Journal of Allergy and Clinical Immunology, 115(2), 302-308. [More Information]
  • Black, J., Ge, Q., Boustany, S., Johnson, P., Poniris, M., Glanville, A., Oliver, B., Moir, L., Burgess, J. (2005). In vitro studies of lymphangioleiomyomatosis. European Respiratory Journal, 26(4), 569-576. [More Information]
  • Brightling, C., Ammit, A., Kaur, D., Black, J., Wardlaw, A., Hughes, M., Bradding, P. (2005). The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle. American Journal of Respiratory and Critical Care Medicine, 171(10), 1103-1108. [More Information]

2004

  • McParland, B., Pare, P., Johnson, P., Armour, C., Black, J. (2004). Airway Basement Membrane Perimeter In Human Airways Is Not A Constant; Potential Implications For Airway Remodeling In Asthma. Journal of Applied Physiology, 97(2), 556-563.
  • Hostettler, K., Roth, M., Burgess, J., Johnson, P., Glanville, A., Tamm, M., Black, J., Borger, P. (2004). Cyclosporine A Mediates Fibroproliferation Through Epithelial Cells. Transplantation, 77(12), 1886-1893.
  • Burgess, J., Carlin, S., Pack, R., Arndt, G., Au, W., Black, J., Johnson, P., Hunt, N. (2004). Detection And Characterization Of Ox40 Ligand Expression In Human Airway Smooth Muscle Cells: A Possible Role In Asthma? Journal of Allergy and Clinical Immunology, 113(4), 683-9. [More Information]
  • Roth, M., Johnson, P., Borger, P., Bihl, M., Rudiger, J., King, G., Ge, Q., Hostettler, K., Burgess, J., Black, J., et al (2004). Dysfunctional Interaction Of C/EBPα And The Glucocorticoid Receptor In Asthmatic Bronchial Smooth-Muscle Cells. New England Journal of Medicine, 351(6), 560-574.
  • Azzola, A., Black, J., Chhajed, P., Roth, M., Johnson, P., Havryk, A., Hostettler, K., Granville, A., Tamm, M. (2004). Everolimus And Mycophenolate Mofetil Are Potent Inhibitors Of Fibroblast Proliferation After Lung Transplantation. Transplantation, 77(2), 275-280.
  • Johnson, P., Burgess, J., Underwood, A., Au, W., Poniris, M., Tamm, M., Ge, Q., Roth, M., Black, J. (2004). Extracellular Matrix Proteins Modulate Asthmatic Airway Smooth Muscle Cell Proliferation Via An Autocrine Mechanism. Journal of Allergy and Clinical Immunology, 113(4), 690-6. [More Information]
  • Burgess, J., Ge, Q., Boustany, S., Black, J., Johnson, P. (2004). Increased Sensitivity Of Asthmatic Airway Smooth Muscle Cells To Prostaglandin E2 Might Be Mediated By Increased Numbers Of E-Prostanoid Receptors. Journal of Allergy and Clinical Immunology, 113(5), 876-881. [More Information]
  • Merrilees, M., Hankin, E., Black, J., Beaumont, B. (2004). Matrix Proteoglycans And Remodelling Of Interstitial Lung Tissue In Lymphangioleiomyomatosis. Journal of Pathology, 203(2), 653-660. [More Information]

2003

  • Black, J., Burgess, J., Johnson, P. (2003). Airway smooth muscle - its relationship to the extracellular matrix. Respiratory Physiology and Neurobiology, 137(2-3), 339-346.
  • Burgess, J., Johnson, P., Ge, Q., Au, W., Poniris, M., McParland, B., King, G., Roth, M., Black, J. (2003). Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine, 167(1), 71-77.
  • McClean, M., Matheson, M., McKay, K., Johnson, P., Rynell, A., Ammit, A., Black, J., Berend, N. (2003). Low lung volume alters contractile properties of airway smooth muscle in sheep. European Respiratory Journal, 22(1), 50-56.
  • Chambers, L., Black, J., Ge, Q., Carlin, S., Au, W., Poniris, M., Thompson, J., Johnson, P., Burgess, J. (2003). PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 285(3), L619-L627.
  • Carlin, S., Roth, M., Black, J. (2003). Urokinase potentiates PDGF-induced chemotaxis of human airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 284(6), L1020-L1026.

2002

  • Borger, P., Black, J., Roth, M. (2002). Asthma and the CCAAT-enhancer binding proteins: A holistic view on airway inflammation and remodeling. Journal of Allergy and Clinical Immunology, 110(6), 841-846.
  • Black, J., Johnson, P. (2002). Factors controlling smooth muscle proliferation and airway remodelling. Current Opinion in Allergy and Clinical Immunology, , 47-51.
  • Page, S., Black, J., Armour, C., Ammit, A., Poulton, S., Speigel, S. (2002). Human lung mast cells as a possible source of sphingosine 1-phosphate (SPP) in asthma. International Conference of the American Thoracic Society, : British Medical Journal Publishing Group.
  • Roth, M., Johnson, P., Rudiger, J., King, G., Ge, Q., Burgess, J., Anderson, G., Tamm, M., Black, J. (2002). Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. The Lancet, 360(9342), 1293-1299.
  • Ammit, A., Black, J., McClean, M., Matheson, M., Berend, N. (2002). MLCK content of tracheal and bronchial smooth muscle in sheep and rabbits. The Thoracic Society of Australia and New Zealand Annual Scientific meeting, 54 University St,P O Box 378, Carlton, Australia, 3053: Blackwell Publishers.

2001

  • Johnson, P., Roth, M., Tamm, M., Hughes, M., Ge, Q., King,, G., Burgess, J., Black, J. (2001). Airway smooth muscle cell proliferation is increased in asthma. American Journal of Respiratory and Critical Care Medicine, 164(3), 474-477.
  • Black, J., Armour, C., Tamm, M., Roth, M., Johnson, P. (2001). Airway Wall remodelling-the role of the smooth muscle. Clinical and Experimental Allergy, 1(2), 116-119.
  • Lee, J., Johnson, P., Roth, M., Hunt, N., Black, J. (2001). ERK activation and mitogenesis in human airway smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 280.
  • Black, J., Johnson, P., Armour, C. (2001). Factors controlling transduction signaling and proliferation of airway smooth muscle. Current Allergy and Asthma Reports, 1, 116-121.
  • Chambers, L., Black, J., Poronnik, P., Johnson, P. (2001). Functional effects of protease-activated receptor-2 stimulation on human airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281.
  • Page, S., Ammit, A., Black, J., Armour, C. (2001). Human mast cell and airway smooth muscle cell interactions: implications for asthma. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281(6, Pt1), L1313-L1323.
  • Black, J., Roth, M., Lee, J., Carlin, S., Johnson, P. (2001). Mechanisms of airway remodelling. American Journal of Respiratory and Critical Care Medicine, 164.
  • Tamm, M., Roth, M., Johnson, P., Black, J., Malouf, M., Chhajed, P., Glanville, A. (2001). Primary fibroblast cell cultures from transbronchial biopsies of lung transplant recipients. Transplantation, 71, 337-339.

2000

  • McKay, K., Johnson, P., Black, J., Armour, C. (2000). Parasympathetic neurotransmission in rabbit isolatedbronchus is modulated at prejunctional sites via endothelinB receptor stimulation. Respirology, 5, 343-353.

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