Dr Justin Beardsley

MBChB, PhD, FRACP
Senior Lecturer in Infectious Diseases at the Marie Bashir Institute
Westmead Clinical School

Telephone 0286273447

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Biographical details

Dr Beardsley is a New Zealand trained infectious disease specialist, fellow of the Royal Australasian College of Physicians, and clinical researcher. He completed his PhD in 2017 through the Oxford University Clinical Research Unit in Ho Chi Minh City. His research in Vietnam was focussed on fungal infections. He conducted a multi-national randomised clinical trial into adjunctive steroid therapy for Cryptococcal Meningitis in South East Asia and Africa (Beardlsey et al, NEJM 2016). His other core research focussed on epidemiology of fungal infections, immune responses in Cryptococcal Meningitis, pharmacokinetics of anti-fungal drugs in the central nervous system, and temporal trends in cryptococcal drug susceptibility. He was involved in several other clinical trials in Cryptococcal Meningitis and hepatitis C, and is a co-author on the Lancet Global Burden of Disease series in his capacity as GBD specialist on Vietnam and HIV.

Dr Beardsley was recently appointed as a Senior Clinical Lecturer at the Marie Bashir Institute, University of Sydney. From that base he will continue his research focus on infectious diseases in resource-limited settings, as a means of impacting global inequalities.

Research interests

Clinical trials

Fungal infections

HIV and AIDS

Tuberculosis

Burden of disease

Civil registration and vital statistics

Current projects

Assessing the prevalence of chronic pulmonary aspergillosis in Vietnam

Anti-fungal resistance in envrionmental samples of Aspergillus in Vietnam

Associations

Member of the NZ Specialist Advisory Committee on Infectious Diseases for the RACP

Member of European Society Clinical Microbiology and Infectious Diseases (including mycology and pharmacology specialist interest groups)

Member of Australasian Infectious Disease Society

Awards and honours

2015 Bill and Melinda Gates Travel Award, to present at ICAAC San Diego

2013 and 2014 Erasmus Mundus Scholar Scholarship to support teaching (global health) at Charite University, Berlin

In the media

Keywords

HIV/AIDS; Therapeutics; Tuberculosis; Infection and immunity

Clinical Specialty

Infection and Immunity

International links

Vietnam

(Oxford University Clinical Research Unit) Honorary clinical research fellow. Multiple research relationships developed after five years working there.

Selected publications

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Journals

  • Stott, K., Beardsley, J., Whalley, S., Kibengo, F., Mai, N., Kolamunnage-Dona, R., Hope, W., Day, J. (2018). Amphotericin B Deoxycholate in adults with Cryptococcal Meningitis; a Population Pharmacokinetic Model and Meta-Analysis of Outcomes. Antimicrobial Agents and Chemotherapy, 62(7), 1-15. [More Information]
  • Beardsley, J., Halliday, C., Chen, S., Sorrell, T. (2018). Responding to the emergence of antifungal drug resistance: Perspectives from the bench and the bedside. Future Microbiology, 13(10), 1175-1191. [More Information]
  • Kyu, H., Maddison, E., Henry, N., Mumford, J., Barber, R., Shields, C., Brown, J., Nguyen, G., Carter, A., Wolock, T., Beardsley, J. (2018). The global burden of tuberculosis: results from the Global Burden of Disease Study 2015. The Lancet Infectious Diseases, 18(3), 261-284. [More Information]
  • Gakidou, E., Afshin, A., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abera, A., Alam, K., Driscoll, T., Leigh, J., Takahashi, K., et al (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1345-1422. [More Information]
  • Hay, S., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abebo, T., Abera, S., Aboyans, V., et al (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990�2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1260-1344. [More Information]
  • Vos, T., Abajobir, A., Abbafati, C., Abbas, K., Abate, K., Abd-Allah, F., Abdulle, A., Abebo, T., Abera, S., Beardsley, J., et al (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1211-1259. [More Information]
  • Fullman, N., Barber, R., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abera, S., Aboyans, V., et al (2017). Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. The Lancet, 2017 (390), 1423-1459. [More Information]
  • Beardsley, J., Wolbers, M., Kibengo, F., Kamali, G., Cuc, N., Binh, T., Chau, N., Farrar, J., Merson, L., Phuong, L., et al (2016). Adjunctive dexamethasone in HIV-associated cryptococcal meningitis. New England Journal of Medicine, 374(6), 543-554. [More Information]
  • Beardsley, J., Wolbers, M., Day, J. (2016). Dexamethasone in Cryptococcal Meningitis. New England Journal of Medicine, 375(2), 189-190. [More Information]
  • Forouzanfar, M., Afshin, A., Alexander, L., Anderson, H., Bhutta, Z., Biryukov, S., Brauer, M., Burnett, R., Cercy, K., Neal, B., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1659-1724. [More Information]
  • Kassebaum, N., Barber, R., Bhutta, Z., Dandona, L., Gething, P., Hay, S., Kinfu, Y., Larson, H., Liang, X., Lim, S., Alam, K., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1775-1812. [More Information]
  • Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Chen, A., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459-1544. [More Information]
  • Wang, H., Bhutta, Z., Coates, M., Coggeshall, M., Dandona, L., Diallo, K., Franca, E., Fraser, M., Fullman, N., Alam, K., Leigh, J., Mekonnen, A., Kemp, A., et al (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725-1774. [More Information]
  • Lim, S., Allen, K., Bhutta, Z., Dandona, L., Forouzanfar, M., Fullman, N., Gething, P., Goldberg, E., Hay, S., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., Neal, B., et al (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1813-1850. [More Information]
  • Beardsley, J., Le, T. (2015). Antiretroviral penetration into the CNS and incidence of AIDS-defining neurologic conditions. Neurology, 84(6), 632-633. [More Information]
  • Beardsley, J., Denning, D., Chau,, N., Yen, N., Crump, J., Day, J. (2015). Estimating the burden of fungal disease in Vietnam. Mycoses, 58, 101-106. [More Information]
  • Naghavi, M., Wang, H., Lozano, R., Davis, A., Liang, X., Zhou, M., Vollset, S., Ozgoren, A., Abdalla, S., Abd-Allah, F., Blyth, F., Leigh, J., et al (2015). Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 385(9963), 117-171. [More Information]
  • Murray, C., Barber, R., Foreman, K., Ozgoren, A., Abd-Allah, F., Abera, S., Aboyans, V., Abraham, J., Driscoll, T., Blyth, F., Kemp, A., Leigh, J., et al (2015). Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition. The Lancet, 386(10009), 2145-2191. [More Information]
  • Fitzmaurice, C., Dicker, D., Pain, A., Hamvid, H., Moradi-Lakeh, M., MacIntyre, M., Allen, C., Hansen, G., Woodbrook, R., Dandona, R., Leigh, J., Driscoll, T., et al (2015). The Global Burden of Cancer 2013. JAMA Oncology, 1(4), 505-527. [More Information]
  • Yew, H., Chambers, S., Roberts, S., Holland, D., Julian, K., Raymond, N., Beardsley, J., Read, K., Murdoch, D. (2014). Association between HACEK bacteraemia and endocarditis. Journal of Medical Microbiology, 63(PART 6), 892-895. [More Information]
  • Day, J., Imran, D., Ganiem, A., Tjahjani, N., Wahyuningsih, R., Adawiyah, R., Dance, D., Mayxay, M., Newton, P., Phetsouvanh, R., et al (2014). CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: Study protocol for a randomised control trial. Trials, 15(1), 1-28. [More Information]
  • Murray, C., Ortblad, K., Guinovart, C., Lim, S., Wolock, T., Roberts, D., Dansereau, E., Graetz, N., Barbara, R., Driscoll, T., Leigh, J., et al (2014). Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 384(9947), 1005-1070. [More Information]
  • Kassebaum, N., Bertozzi-Villa, A., Coggeshall, M., Shackelford, K., Steiner, C., Heuton, K., Gonzalez-Medina, D., Barber, R., Kemp, A., Driscoll, T., et al (2014). Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 384(9947), 980-1004. [More Information]
  • Beardsley, J., Morar, B., Blackmore, T. (2011). Antimicrobial consumption data from New Zealand hospitals. New Zealand Medical Journal, 124(1341), 83-85.

2018

  • Stott, K., Beardsley, J., Whalley, S., Kibengo, F., Mai, N., Kolamunnage-Dona, R., Hope, W., Day, J. (2018). Amphotericin B Deoxycholate in adults with Cryptococcal Meningitis; a Population Pharmacokinetic Model and Meta-Analysis of Outcomes. Antimicrobial Agents and Chemotherapy, 62(7), 1-15. [More Information]
  • Beardsley, J., Halliday, C., Chen, S., Sorrell, T. (2018). Responding to the emergence of antifungal drug resistance: Perspectives from the bench and the bedside. Future Microbiology, 13(10), 1175-1191. [More Information]
  • Kyu, H., Maddison, E., Henry, N., Mumford, J., Barber, R., Shields, C., Brown, J., Nguyen, G., Carter, A., Wolock, T., Beardsley, J. (2018). The global burden of tuberculosis: results from the Global Burden of Disease Study 2015. The Lancet Infectious Diseases, 18(3), 261-284. [More Information]

2017

  • Gakidou, E., Afshin, A., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abera, A., Alam, K., Driscoll, T., Leigh, J., Takahashi, K., et al (2017). Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1345-1422. [More Information]
  • Hay, S., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abebo, T., Abera, S., Aboyans, V., et al (2017). Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990�2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1260-1344. [More Information]
  • Vos, T., Abajobir, A., Abbafati, C., Abbas, K., Abate, K., Abd-Allah, F., Abdulle, A., Abebo, T., Abera, S., Beardsley, J., et al (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016. The Lancet, 390(10100), 1211-1259. [More Information]
  • Fullman, N., Barber, R., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abdulle, A., Abera, S., Aboyans, V., et al (2017). Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. The Lancet, 2017 (390), 1423-1459. [More Information]

2016

  • Beardsley, J., Wolbers, M., Kibengo, F., Kamali, G., Cuc, N., Binh, T., Chau, N., Farrar, J., Merson, L., Phuong, L., et al (2016). Adjunctive dexamethasone in HIV-associated cryptococcal meningitis. New England Journal of Medicine, 374(6), 543-554. [More Information]
  • Beardsley, J., Wolbers, M., Day, J. (2016). Dexamethasone in Cryptococcal Meningitis. New England Journal of Medicine, 375(2), 189-190. [More Information]
  • Forouzanfar, M., Afshin, A., Alexander, L., Anderson, H., Bhutta, Z., Biryukov, S., Brauer, M., Burnett, R., Cercy, K., Neal, B., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1659-1724. [More Information]
  • Kassebaum, N., Barber, R., Bhutta, Z., Dandona, L., Gething, P., Hay, S., Kinfu, Y., Larson, H., Liang, X., Lim, S., Alam, K., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1775-1812. [More Information]
  • Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Chen, A., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., et al (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1459-1544. [More Information]
  • Wang, H., Bhutta, Z., Coates, M., Coggeshall, M., Dandona, L., Diallo, K., Franca, E., Fraser, M., Fullman, N., Alam, K., Leigh, J., Mekonnen, A., Kemp, A., et al (2016). Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1725-1774. [More Information]
  • Lim, S., Allen, K., Bhutta, Z., Dandona, L., Forouzanfar, M., Fullman, N., Gething, P., Goldberg, E., Hay, S., Alam, K., Driscoll, T., Kemp, A., Leigh, J., Mekonnen, A., Neal, B., et al (2016). Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet, 388(10053), 1813-1850. [More Information]

2015

  • Beardsley, J., Le, T. (2015). Antiretroviral penetration into the CNS and incidence of AIDS-defining neurologic conditions. Neurology, 84(6), 632-633. [More Information]
  • Beardsley, J., Denning, D., Chau,, N., Yen, N., Crump, J., Day, J. (2015). Estimating the burden of fungal disease in Vietnam. Mycoses, 58, 101-106. [More Information]
  • Naghavi, M., Wang, H., Lozano, R., Davis, A., Liang, X., Zhou, M., Vollset, S., Ozgoren, A., Abdalla, S., Abd-Allah, F., Blyth, F., Leigh, J., et al (2015). Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 385(9963), 117-171. [More Information]
  • Murray, C., Barber, R., Foreman, K., Ozgoren, A., Abd-Allah, F., Abera, S., Aboyans, V., Abraham, J., Driscoll, T., Blyth, F., Kemp, A., Leigh, J., et al (2015). Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition. The Lancet, 386(10009), 2145-2191. [More Information]
  • Fitzmaurice, C., Dicker, D., Pain, A., Hamvid, H., Moradi-Lakeh, M., MacIntyre, M., Allen, C., Hansen, G., Woodbrook, R., Dandona, R., Leigh, J., Driscoll, T., et al (2015). The Global Burden of Cancer 2013. JAMA Oncology, 1(4), 505-527. [More Information]

2014

  • Yew, H., Chambers, S., Roberts, S., Holland, D., Julian, K., Raymond, N., Beardsley, J., Read, K., Murdoch, D. (2014). Association between HACEK bacteraemia and endocarditis. Journal of Medical Microbiology, 63(PART 6), 892-895. [More Information]
  • Day, J., Imran, D., Ganiem, A., Tjahjani, N., Wahyuningsih, R., Adawiyah, R., Dance, D., Mayxay, M., Newton, P., Phetsouvanh, R., et al (2014). CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: Study protocol for a randomised control trial. Trials, 15(1), 1-28. [More Information]
  • Murray, C., Ortblad, K., Guinovart, C., Lim, S., Wolock, T., Roberts, D., Dansereau, E., Graetz, N., Barbara, R., Driscoll, T., Leigh, J., et al (2014). Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 384(9947), 1005-1070. [More Information]
  • Kassebaum, N., Bertozzi-Villa, A., Coggeshall, M., Shackelford, K., Steiner, C., Heuton, K., Gonzalez-Medina, D., Barber, R., Kemp, A., Driscoll, T., et al (2014). Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 384(9947), 980-1004. [More Information]

2011

  • Beardsley, J., Morar, B., Blackmore, T. (2011). Antimicrobial consumption data from New Zealand hospitals. New Zealand Medical Journal, 124(1341), 83-85.

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