Dr Kim Sally Bell-Anderson

Senior Lecturer
School of Molecular Bioscience
Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders

G08 - Biochemistry Building
The University of Sydney
NSW 2006 Australia

T: +61 2 9351 6267
F: +61 2 9361 6022

Biographical details

Obesity is fast becoming one of the most important public health problems. With now 1 billion people affected worldwide, this has increased the prevalence of the Metabolic Syndrome, risk of cardiovascular disease (CVD) and type 2 diabetes.

Research interests

Dissecting the role of Kruppel-like factor 3 (KLF3) using knockout mice

Mice lacking a functional KLF3 gene are skinny and resistant to diet-induced obesity and insulin resistance. Through microarray analysis of differential gene expression we are identifying Klf3 target genes and working towards defining the molecular mechanisms underlying their lean phenotype.

Acute nutrient regulation of insulin sensitivity

Fat-fed insulin resistant rats can be made insulin sensitive by changing their diet. This occurs within 12 hours and suggests that nutrients can acutely modulate insulin action. The mechanism responsible is not known. We are investigating the role of the gastrointestinal tract, restricted feeding and diet composition on the reversal of this fat-induced insulin resistance in the rat. Future studies will investigate the effect of protein quality on whole body insulin sensitivity in rodents