Dr Kellie Charles
D06 - Blackburn Building
Dr Charles' research aims to investigate the interactions between malignant cells and immune cells that regulate tumour progression.Malignant cells secrete cytokines and chemokines that alter the phenotype and behaviour of tumour-associated leucocytes to promote tumour growth and orchestrate the immunosuppressant behaviour of the adaptive immune responses. Inhibiting the communication between cancer cells and immune cells is becoming an exciting potential target for cancer intervention strategies. Dr Charles conducts translational and clinical studies aimed to identify new molecular targets in cancer and in collaboration with biological chemists at the University of Sydney design and evaluate new cancer therapeutic agents.
United Kingdom. (Centre of Cancer and Inflammation
Institute of Cancer and CRUK Clinical School
School of Medicine and Dentistry
Queen Mary, University of London and Barts
London, UK, EC1M6BQ) Collaboration with Prof Frances Balkwill and Dr Thorsten Hagemann.