Professor Kenneth Bradstock

Clinical Professor
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 7073
Fax +61 2 9689 2331

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Biographical details

Professor Bradstock is a clinical hematologist at Westmead Hospital with research interests in the treatment of hematological malignancies, and a focus on allogeneic bone marrow transplantation. He is involved in numerous clinical trials in leukemia and lymphoma, and has an active interest in developing new therapeutics for the treatment of acute lymphoblastic leukemia. He is also a member of the Dendritic Cell Biology and Therapeutics Group at the Anzac Research Institute, and, with Professor Derek Hart, is involved in developing new approaches for treatment of graft-versus-host disease based on a better understanding of the role of dendritic cells in this disease.

Selected grants

2013

  • A randomised study to optimise clinical outcomes in patients with FLT3 mutant AML; Wei A, Bradstock K, Levis M, Murray M, Roberts A; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Enabling Diagnostic and Therapeutic Antibodies for Haematological and other Malignancies; Hart D, Bradstock K, Joshua D; Cancer Institute New South Wales/Translational Program Grant.

2011

  • The BD Influx High Speed Cell Sorter; Cunningham A, George J, Rizos H, Clarke C, Reddel R, Kefford R, North K, Stewart G, Jones C, Tam P, Alexander S, Gottlieb D, Bradstock K, Bryan T, Booth D, Bendall L, Brilot-Turville F, Hebbard L, Cooper S, Wang Y, Wang X; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Sphingosine-1-phosphate receptor agonists as adjunct mobilizing agents - Improving Hematopoietic Stem Cell Mobilization; Bendall L, Bradstock K; Anthony Rothe Foundation/Research Support.

2010

  • The Translation of Dendritic Cell Biology into Clinical Practice; Hart D, Bradstock K; National Health and Medical Research Council (NHMRC)/Program Grants.

2008

  • Enhancement of the effects of cytotoxic agents by mTOR inhibitors in acute lymphoblastic leukemia; Bendall L, Bradstock K; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Antagonists of p38 MAPK as therapeutics for acute lymphoblastic leukemia.; Bendall L, Bradstock K; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • Enhancement of the effects of cytotoxic agents by mTOR inhibitors in acute lymphoblastic leukemia; Bradstock K, Bendall L; Leukemia and Lymphoma Society (USA)/Research Grant.
  • Flow Cytometry support; Alexander S, Braithwaite A, Bradstock K, Bendall L, Gunning P, Henderson B, Kefford R, Reddel R, Rizos H, Jones C, Byrne J; Cancer Institute New South Wales/Infrastructure Grant.

2006

  • Infrastructure; Bradstock K, Kefford R; Australian Cancer Research Fund/Research Support.

2005

  • LSRII flow cytometer; Bradstock K; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Interdisciplinary Clinical And Health Ethic Research And Training To Improve Outcomes In Immunosuppressed Haematology Patients; Sorrell T, Bradstock K, Kerridge I, Gilbert G, Gottlieb D, MacIntyre C, Dwyer D, Ankeny R; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • CXCR4 antagonists in acute lymphoblastic leukemias in NOD/SCID mice; Bendall L, Bradstock K; National Health and Medical Research Council (NHMRC)/Project Grants.

2004

  • A randomized trial of Idarubicin dose escalation in consolidation therapy for adult acute myeloid leukemia; Bradstock K, Seymour J; National Health and Medical Research Council (NHMRC)/Project Grants.

2001

  • Analysis of the effect of CD44 variant exon 6 expression on adhesion and migration of human leukemic cells; Bendall L, Bradstock K, Gottlieb D; Leo and Jenny Leukaemia and Cancer Foundation/Leukaemia and Cancer Foundation.

2000

  • An animal model of regulatory interactions between acute leukaemia and bone marrow stroma; Bradstock K, Gottlieb D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Analysis of cellular immune response to melanoma antigens after allogenic haemopoietic stem cell transplantation; Gottlieb D, Kefford R, Bradstock K; Cancer Council New South Wales/Research Project Grants.

1999

  • A randomised trial of high dose cytarabine in initial therapy for acute myeloid leukaemia; Bradstock K; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Harun, N., Bradstock, K., Bendall, L. (2012). Combination Strategies for Stem Cell Mobilization Targeting CXCR4 and S1P Receptors. In Stefan Fruehauf, W. Jens Zeller and Gary Calandra (Eds.), Novel Developments in Stem Cell Mobilization, (pp. 37-54). New York: Springer Science + Business Media.

Journals

  • Gasiorowski, R., Clark, G., Bradstock, K., Hart, D. (2014). Antibody therapy for acute myeloid leukaemia. British Journal of Haematology, 164(4), 481-495. [More Information]
  • Raj, K., Pagliuca, A., Bradstock, K., Noriega, V., Potter, V., Streetly, M., McLornan, D., Kazmi, M., Marsh, J., Kwan, J., et al (2014). Peripheral Blood Hematopoietic Stem Cells for Transplantation of Hematological Diseases from Related, Haploidentical Donors after Reduced-Intensity Conditioning. Biology of Blood and Marrow Transplantation, 20(6), 890-895. [More Information]
  • Nivison-Smith, I., Simpson, J., Dodds, A., Ma, D., Szer, J., Bradstock, K. (2013). A population-based analysis of the effect of autologous hematopoietic cell transplant in the treatment of multiple myeloma. Leukemia and Lymphoma, 54(8), 1671-1676. [More Information]
  • Shahin, K., Sartor, M., Hart, D., Bradstock, K. (2013). Alterations in Chemokine Receptor CCR5 Expression on Blood Dendritic Cells Correlate With Acute Graft-Versus-Host Disease. Transplantation, 96(8), 753-762. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Milliken, S., Bardy, P., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Moore, J., et al (2013). Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial. Lancet Infectious Diseases, 13(6), 519-528. [More Information]
  • Bilmon, I., Kwan, J., Gottlieb, D., Kerridge, I., McGurgan, M., Huang, G., George, B., Hertzberg, M., Bradstock, K. (2013). Haploidentical bone marrow transplants for hematological malignancies using non-myeloablative conditioning therapy and post-transplant immunosuppression with cyclophosphamide: results from a single Australian centre. Internal Medicine Journal, 43(2), 191-196. [More Information]
  • Wallington-Beddoe, C., Bradstock, K., Bendall, L. (2013). Oncogenic properties of sphingosine kinases in haematological malignancies. British Journal of Haematology, 161(5), 623-638. [More Information]
  • Welschinger, R., Liedtke, F., Basnett, J., Dela Pena, A., Juarez, J., Bradstock, K., Bendall, L. (2013). Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice. Experimental Hematology, 41(3), 293-302.e1. [More Information]
  • Heatley, S., Pietra, G., Lin, J., Widjaja, J., Harpur, C., Lester, S., Rossjohn, J., Szer, J., Schwarer, A., Bradstock, K., et al (2013). Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells. The Journal of Biological Chemistry, 288(12), 8679-8690. [More Information]
  • Saunders, P., Weiss, J., Welschinger, R., Baraz, R., Bradstock, K., Bendall, L. (2013). RAD001 (everolimus) induces dose-dependent changes to cell cycle regulation and modifies the cell cycle response to vincristine. Oncogene, 32(40), 4789-4797. [More Information]
  • George, B., Kerridge, I., Gilroy, N., Huang, G., Hertzberg, M., Bradstock, K., Gottlieb, D. (2012). A risk score for early cytomegalovirus reactivation after allogeneic stem cell transplantation identifies low-, intermediate-, and high-risk groups: reactivation risk is increased by graft-versus-host disease only in the intermediate-risk group. Transplant Infectious Disease (Print), 14(2), 141-148. [More Information]
  • Iland, H., Bradstock, K., Supple, S., Catalano, A., Collins, M., Hertzberg, M., Browett, P., Grigg, A., Firkin, F., Hugman, A., et al (2012). All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4). Blood, 120(8), 1570-1580. [More Information]
  • Nivison-Smith, I., Dodds, A., Butler, J., Bradstock, K., Ma, D., Simpson, J., Szer, J. (2012). Allogeneic Hematopoietic Cell Transplantation for Chronic Myelofibrosis in Australia and New Zealand: Older Recipients Receiving Myeloablative Conditioning at Increased Mortality Risk. Biology of Blood and Marrow Transplantation, 18(2), 302-308. [More Information]
  • Wallington-Beddoe, C., Don, A., Hewson, J., Qiao, Q., Papa, R., Lock, R., Bradstock, K., Bendall, L. (2012). Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia. PLoS One, 7(5), 1-7. [More Information]
  • Khan, N., Cisterne, A., Baraz, R., Bradstock, K., Bendall, L. (2012). Para-NO-aspirin inhibits NF-kB and induces apoptosis in B-cell progenitor acute lymphoblastic leukemia. Experimental Hematology, 40(3), 207-215.e1. [More Information]
  • Iland, H., Bradstock, K., Seymour, J., Hertzberg, M., Grigg, A., Taylor, K., Catalano, J., Cannell, P., Horvath, N., Deveridge, S., et al (2012). Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia. Haematologica: the hematology journal, 97(2), 227-234. [More Information]
  • van der Jagt, A., Muirhead, J., Seymour, J., Bradstock, K., Paul, E., Wei, A. (2012). Risk factors for early death after high-dose cytosine arabinoside (HiDAC)-based chemotherapy for adult AML. Leukemia, 26(2), 362-365. [More Information]
  • Juarez, J., Harun, N., Thien, M., Welschinger, R., Baraz, R., Dela Pena, A., Pitson, S., Rettig, M., DiPersio, J., Bradstock, K., Bendall, L. (2012). Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice. Blood, 119(3), 707-716. [More Information]
  • Nivison-Smith, I., Dodds, A., Doocey, R., Ganly, P., Gibson, J., Ma, D., Simpson, J., Szer, J., Bradstock, K., Bradstock, K. (2011). Allogeneic hematopoietic cell transplant for multiple myeloma using reduced intensity conditioning therapy, 1998-2006: factors associated with improved survival outcome. Leukemia and Lymphoma, 52(9), 1727-1735. [More Information]
  • Fromm, P., Gottlieb, D., Bradstock, K., Hart, D. (2011). Cellular therapy to treat haematological and other malignancies: progress and pitfalls. Pathology, 43(6), 605-615. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Schwarer, A., Slavin, M. (2011). Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies. Leukemia and Lymphoma, 52(2), 179-193. [More Information]
  • Wallington-Beddoe, C., Hewson, J., Bradstock, K., Bendall, L. (2011). FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells. Autophagy, 7(7), 707-715. [More Information]
  • Nivison-Smith, I., Dodds, A., Dunckley, H., Ma, D., Moore, J., Simpson, J., Szer, J., Bradstock, K. (2011). Increased activity and improved outcome in unrelated donor haemopoietic cell transplants for acute myeloid leukaemia in Australia, 1992-2005. Internal Medicine Journal, 41(1A), 27-34. [More Information]
  • Bray, L., Jordens, C., Rowlings, P., Bradstock, K., Kerridge, I. (2011). The long haul: Caring for bone marrow transplant patients in regional Australia. Australian Journal of Advanced Nursing, 29(1), 5-13.
  • Saunders, P., Cisterne, A., Weiss, J., Bradstock, K., Bendall, L. (2011). The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia. Haematologica: the hematology journal, 96(1), 69-77. [More Information]
  • Murray, P., Kerridge, I., Tiley, C., Catanzariti, A., Welberry, H., Lean, C., Sinclair, S., Bishop, J., Bradstock, K. (2010). Enrolment of patients to clinical trials in haematological cancer in New South Wales: Current status, perceived barriers and opportunities for improvement. Internal Medicine Journal, 40(2), 133-138. [More Information]
  • George, B., Kerridge, I., Gilroy, N., Huang, G., Hertzberg, M., Gottlieb, D., Bradstock, K. (2010). Fludarabine-based reduced intensity conditioning transplants have a higher incidence of cytomegalovirus reactivation compared with myeloablative transplants. Bone Marrow Transplantation, 45(5), 849-855. [More Information]
  • George, B., Pati, N., Gilroy, N., Ratnamohan, M., Huang, G., Kerridge, I., Hertzberg, M., Gottlieb, D., Bradstock, K. (2010). Pre-transplant cytomegalovirus (CMV) serostatus remains the most important determinant of CMV reactivation after allogeneic hematopoietic stem cell transplantation in the era of surveillance and preemptive therapy. Transplant Infectious Disease (Print), 12(4), 322-329. [More Information]
  • Spencer, A., Prince, H., Roberts, A., Prosser, I., Bradstock, K., Coyle, L., Gill, D., Horvath, N., Reynolds, J., Kennedy, N. (2009). Consolidation Therapy With Low-Dose Thalidomide and Prednisolone Prolongs the Survival of Multiple Myeloma Patients Undergoing a Single Autologous Stem-Cell Transplantation Procedure. Journal of Clinical Oncology, 27(11), 1788-1793. [More Information]
  • Juarez, J., Thien, M., Dela Pena, A., Baraz, R., Bradstock, K., Bendall, L. (2009). CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK. British Journal of Haematology, 145, 491-499. [More Information]
  • Brooke, G., Rossetti, T., Pelekanos, R., Ilic, N., Murray, P., Hancock, S., Antonenas, V., Huang, G., Gottlieb, D., Bradstock, K., et al (2009). Manufacturing of human placenta-derived mesenchymal stem cells for clinical trials. British Journal of Haematology, 144(4), 571-579. [More Information]
  • Deo, S., Bradstock, K., Bendall, L. (2009). p38MAPK inhibitors attenuate cytokine production by bone marrow stromal cells and reduce stroma-mediated proliferation of acute lymphoblastic leukemia cells. Cell Cycle, 8(18), 2977-2985. [More Information]
  • Ferguson, P., Sorrell, T., Bradstock, K., Carr, P., Gilroy, N. (2009). Parainfluenza Virus Type 3 Pneumonia in Bone Marrow Transplant Recipients: Multiple Small Nodules in High-Resolution Lung Computed Tomography Scans Provide a Radiological Clue to Diagnosis. Clinical Infectious Diseases, 48(7), 905-909. [More Information]
  • Crazzolara, R., Cisterne, A., Thien, M., Hewson, J., Baraz, R., Bradstock, K., Bendall, L. (2009). Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia. Blood, 113(14), 3297-3306. [More Information]
  • Crazzolara, R., Bradstock, K., Bendall, L. (2009). RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia. Autophagy, 5(5), 727-728. [More Information]
  • Nivison-Smith, I., Simpson, J., Dodds, A., Ma, D., Szer, J., Bradstock, K. (2009). Relative Survival of Long-Term Hematopoietic Cell Transplant Recipients Approaches General Population Rates. Biology of Blood and Marrow Transplantation, 15(10), 1323-1330. [More Information]
  • Bradstock, K., Hertzberg, M., Kerridge, I., Svennilson, J., George, B., McGurgan, M., Huang, G., Antonenas, V., Gottlieb, D. (2009). Single versus double unrelated umbilical cord blood units for allogeneic transplantation in adults with advanced hematological malignancies: a retrospective comparison of outcomes. Internal Medicine Journal, 39(11), 744-751. [More Information]
  • George, B., Kerridge, I., Gottlieb, D., Huang, G., Hertzberg, M., Svennilson, J., Bradstock, K. (2008). A reduced intensity conditioning protocol associated with excellent survival in patients with myelofibrosis. Bone Marrow Transplantation, 42(8), 567-568. [More Information]
  • Bradstock, K. (2008). Can the influence of karyotype in acute myeloid leukemia be overcome by high-dose chemotherapy? Leukemia and Lymphoma, 49(12), 2227-2228. [More Information]
  • Khan, N., Cisterne, A., Devidas, M., Shuster, J., Hunger, S., Shaw, P., Bradstock, K., Bendall, L. (2008). Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics. Leukemia and lymphoma, 49(4), 710-718. [More Information]
  • Mullighan, C., Heatley, S., Danner, S., Dean, M., Doherty, K., Hahn, U., Bradstock, K., Minchinton, R., Schwarer, A., Szer, J., et al (2008). Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation. Blood, 112(5), 2120-2128.
  • Micklethwaite, K., Clancy, L., Sandher, U., Hansen, A., Blyth, E., Antonenas, V., Sartor, M., Bradstock, K., Gottlieb, D. (2008). Prophylactic infusion of cytomegalovirus specific cytotoxic T-lymphocytes stimulated with Ad5f35pp65 gene modified dendritic cells following allogeneic haemopoietic stem cell transplantation. Blood, 112(10), 3974-3981. [More Information]
  • Grigg, A., Gibson, J., Bardy, P., Reynolds, J., Shuttleworth, P., Koelmeyer, R., Szer, J., Roberts, A., To, L., Kennedy, G., Bradstock, K. (2007). A prospective multicenter trial of peripheral blood stem cell sibling allografts for acute myeloid leukemia in first complete remission using fludarabine-cyclophosphamide reduced intensity conditioning. Biology of Blood and Marrow Transplantation, 13(5), 560-567. [More Information]
  • Lau, J., Sartor, M., Bradstock, K., Vuckovic, S., Munster, D., Hart, D. (2007). Activated circulating dendritic cells after hematopoietic stem cell transplantation predict acute graft-versus-host disease. Transplantation, 83(7), 839-846. [More Information]
  • Khan, N., Bradstock, K., Bendall, L. (2007). Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia. British Journal of Haematology, 138(3), 338-348. [More Information]
  • Juarez, J., Dela Pena, A., Baraz, R., Hewson, J., Khoo, M., Cisterne, A., Fricker, S., Fujii, N., Bradstock, K., Bendall, L. (2007). CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment. Leukemia, 21(6), 1249-1257. [More Information]
  • Moore, J., Nivison-Smith, I., Goh, K., Ma, D., Bradstock, K., Szer, J., Durrant, S., Schwarer, A., Bardy, P., Herrmann, R., et al (2007). Equivalent survival for sibling and unrelated donor allogeneic stem cell transplantation for acute myelogenous leukemia. Biology of Blood and Marrow Transplantation, 13(5), 601-607. [More Information]
  • Micklethwaite, K., Hansen, A., Foster, A., Snape, E., Antonenas, V., Sartor, M., Shaw, P., Bradstock, K., Gottlieb, D. (2007). Ex vivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 13(6), 707-714. [More Information]
  • Sartor, M., Garvin, F., Antonenas, V., Bradstock, K., Gottlieb, D. (2007). Failure to achieve a threshold dose of CD34(+)CD110(+) progenitor cells in the graft predicts delayed platelet engraftment after autologous stem cell transplantation. Bone Marrow Transplantation, 40(9), 851-857. [More Information]
  • Nivison-Smith, I., Bradstock, K., Dodds, A., Hawkins, P., Ma, D., Moore, J., Simpson, J., Szer, J. (2007). Hematopoietic stem cell transplantation in Australia and New Zealand, 1992-2004. Biology of Blood and Marrow Transplantation, 13(8), 905-912. [More Information]
  • Juarez, J., Baraz, R., Deo, S., Bradstock, K., Bendall, L. (2007). Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia. Haematologica: the hematology journal, 92(4), 450-459. [More Information]
  • Tavernier, E., Boiron, J., Huguet, F., Bradstock, K., Vey, N., Kovacsovics, T., Delannoy, A., Fegueux, N., Fenaux, P., Stamatoullas, A., et al (2007). Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial. Leukemia, 21(9), 1907-1914. [More Information]
  • Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy, 9(2), 133-143. [More Information]
  • Feyler, S., Prince, H., Pearce, R., Towlson, K., Nivison-Smith, I., Schey, S., Gibson, J., Patton, N., Bradstock, K., Marks, D., et al (2007). The role of high-dose therapy and stem cell rescue in the management of T-cell malignant lymphomas: a BSBMT and ABMTRR study. Bone Marrow Transplantation, 40(5), 443-450. [More Information]
  • Hill, G., Morris, E., Fuery, M., Hutchins, C., Butler, J., Grigg, A., Roberts, A., Bradstock, K., Szer, J., Kennedy, G., et al (2006). Allogeneic stem cell transplantation with peripheral blood stem cells mobilized by pegylated G-CSF. Biology of Blood and Marrow Transplantation, 12(6), 603-607. [More Information]
  • Belov, L., Mulligan, S., Barber, N., Woolfson, A., Scott, M., Stoner, K., Chrisp, J., Sewell, W., Bradstock, K., Bendall, L., Sartor, M., Young, G., Wiley, J., Christopherson, R., et al (2006). Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray. British Journal of Haematology, 135(2), 184-97. [More Information]
  • Dhedin, N., Dombret, H., Thomas, X., Lheritier, V., Boiron, J., Rigal-Huguet, F., Vernant, J., Kuentz, M., Reman, O., Bradstock, K., et al (2006). Autologous stem cell transplantation in adults with acute lymphoblastic leukemia in first complete remission: analysis of the LALA-85,-87 and-94 trials. Leukemia, 20(2), 336-344.
  • Bradstock, K. (2006). Chemotherapy for patients with acute myeloid leukemia in first remission. Current Hematologic Malignancy Reports, 1(2), 108-113. [More Information]
  • Lau, J., Sartor, M., Vuckovic, S., Munster, D., Bradstock, K., Hart, D. (2006). Expression of activation marker, CMRF-44, on blood CD11c(hi) dendritic cells is closely associated with the severity of acute gvhd after allogeneic haematopoietic stem cell transplant. Immunology and Cell Biology, 84(3), A9-A9.
  • Antonenas, V., Garvin, F., Webb, M., Sartor, M., Bradstock, K., Gottlieb, D. (2006). Fresh PBSC harvests, but not BM, show temperature-related loss of CD34 viability during storage and transport. Cytotherapy, 8(2), 158-165. [More Information]
  • Gottlieb, D., Li, Y., Lionello, I., Tanzarella, S., Marangolo, M., Bradstock, K., Russo, V., Traversari, C. (2006). Generation of tumour-specific cytotoxic T-cell clones from histocompatibility leucocyte antigen-identical siblings of patients with melanoma. British Journal of Cancer, 95(2), 181-188. [More Information]
  • Hertzberg, M., Crombie, C., Benson, W., Taper, J., Gottlieb, D., Bradstock, K. (2006). Outpatient fractionated ifosfamide, carboplatin and etoposide as salvage therapy in relapsed and refractory non-Hodgkin's and Hodgkin's lymphoma. Annals of Oncology, 17 Suppl 4, iv25-iv30. [More Information]
  • Grigg, A., Shuttleworth, P., Reynolds, J., Schwarer, A., Szer, J., Bradstock, K., Hui, C., Herrmann, R., Ebeling, P. (2006). Pamidronate reduces bone loss after allogeneic stem cell transplantation. Journal of Clinical Endocrinology and Metabolism, 91(10), 3835-3843. [More Information]
  • Hertzberg, M., Grigg, A., Gottlieb, D., Szer, J., Roberts, A., Hoyt, R., Huang, G., Bradstock, K. (2006). Reduced-intensity allogeneic haemopoietic stem cell transplantation induces durable responses in patients with chronic B-lymphoproliferative disorders. Bone Marrow Transplantation, 37(10), 923-928. [More Information]
  • Halliday, C., Hoile, R., Sorrell, T., James, G., Yadav, S., Shaw, P., Bleakley, M., Bradstock, K., Chen, S. (2006). Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia. British Journal of Haematology, 132(4), 478-486. [More Information]
  • Crowther, H., Collins, D., Antonenas, V., McGurgan, M., Kerridge, I., Gottlieb, D., Bradstock, K. (2006). Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins. Bone Marrow Transplantation, 37(3), 329-330. [More Information]
  • Crowther, H., Collins, D., Antonenas, V., McGurgan, M., Kerridge, I., Gottlieb, D., Bradstock, K. (2006). Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins. Bone Marrow Transplantation, 37(3), 329-330.
  • Bradstock, K., Hertzberg, M., Kerridge, I., Svennilson, J., McGurgan, M., Huang, G., Antonenas, V., Gottlieb, D. (2006). Unrelated umbilical cord blood transplantation for adults with haematological malignancies: results from a single Australian centre. Internal Medicine Journal, 36(6), 355-361. [More Information]
  • Bradstock, K., Matthews, J., Lowenthal, R., Baxter, H., Catalano, J., Brighton, T., Gill, D., Eliadis, P., Joshua, D., Cannell, P., Koutts, J., Young, G., et al (2005). A randomized trial of high- versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine. Blood, 105(2), 481-488.
  • Sader, M., McGrath, K., Hill, M., Bradstock, K., Jimenez, M., Handelsman, D., Celermajer, D., Heather, A. (2005). Androgen receptor gene expression in leucocytes is hormonally regulated: implications for gender differences in disease pathogenesis. Clinical Endocrinology, 62(1), 56-63. [More Information]
  • Bendall, L., Baraz, R., Juarez, J., Shen, W., Bradstock, K. (2005). Defective p38 mitogen-activated protein kinase signaling impairs chemotaxic but not proliferative responses to stromal-derived factor-1alpha in acute lymphoblastic leukemia. Cancer Research. [More Information]
  • Schmitz, N., Beksac, M., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Szer, J., Bradstock, K., et al (2005). Filgrastim-mobilized peripheral blood progenitor cells versus bone marrow transplantation for treating leukemia: 3-year results from the EBMT randomized trial. Haematologica: the hematology journal, 90(5), 643-648. [More Information]
  • Campana, D., Iwamoto, D., Bendall, L., Bradstock, K. (2005). Growth requirements and immunophenotype of acute lymphoblastic leukemia progenitors. Blood, 105(10), 4150. [More Information]
  • Nivison-Smith, I., Bradstock, K., Dodds, A., Hawkins, P., Szer, J. (2005). Haemopoietic stem cell transplantation in Australia and New Zealand, 1992-2001: progress report from the Australasian Bone Marrow Transplant Recipient Registry. Internal Medicine Journal, 35(1), 18-27. [More Information]
  • Favaloro, E., Bonar, R., Kershaw, G., Sioufi, J., Thom, J., Baker, R., Hertzberg, M., Street, A., Lloyd, J., Marsden, K., Hewson, J., Bradstock, K., Sartor, M., Wong, S., Fulcher, D., et al (2005). Laboratory diagnosis of von Willebrand disorder: use of multiple functional assays reduces diagnostic error rates. Laboratory Hematology, 11(2), 91-97. [More Information]
  • Bradstock, K. (2005). Lymphoma: the good, the bad and the ugly. Medicine Today, 6(9), 25-33.
  • Bendall, L., Bradstock, K. (2005). New therapies targeting chemokine receptors: Can changing the way cells traffic be used to treat human disease? Current Topics in Membranes, 55, 331-365.
  • Barton, G., Forrester, K., Bradstock, K., Gottlieb, D., Foster, A. (2005). Optimizing bioreactor productivity for therapeutic immune cells. Food and Bioproducts Processing, 83(C2), 158-163.
  • Sartor, M., Antonenas, V., Garvin, F., Webb, M., Bradstock, K. (2005). Recovery of viable CD34þ cells from cryopreserved hemopoietic progenitor cell products. Bone Marrow Transplantation, 36(3), 199-204. [More Information]
  • Foster, A., Bradstock, K., Sili, U., Marangolo, M., Rooney, C., Gottlieb, D. (2004). A Comparison Of Gene Transfer And Antigen-Loaded Dendritic Cells For The Generation Of Cd4+ And Cd8+ Cytomegalovirus-Specific T Cells In Hla-A2+ And Hla-A2- Donors. Biology of Blood and Marrow Transplantation, 10(11), 761-771. [More Information]
  • Bradstock, K. (2004). Adult leukaemias: prognostic classification and treatment. Medicine Today, 5(5), 41-47.
  • Juarez, J., Bendall, L., Bradstock, K. (2004). Chemokines And Their Receptors As Therapeutic Targets: The Role Of The Sdf-1/Cxcr4 Axis. Current Pharmaceutical Design, 10(11), 1245-1259.
  • McGowan, E., Saad, S., Bendall, L., Bradstock, K., Clarke, C. (2004). Effect Of Progesterone Receptor A Predominance On Breast Cancer Cell Migration Into Bone Marrow Fibroblasts. Breast Cancer Research and Treatment, 83(3), 211-220.
  • Foster, A., Marangolo, M., Sartor, M., Alexander, S., Hu, M., Bradstock, K., Gottlieb, D. (2004). Human Cd62L- Memory T Cells Are Less Responsive To Alloantigen Stimulation Than Cd62L+ Naive T Cells: Potential For Adoptive Immunotherapy And Allodepletion. Blood, 104(8), 2403-2409.
  • Mollee, P., Arthur, C., Hughes, T., Januszewicz, H., Grigg, A., Bradstock, K., Wolf, M., Gibson, J., Schwarer, A., Spencer, A., et al (2004). Interferon-Alpha-2B And Oral Cytarabine Ocfosfate For Newly Diagnosed Chronic Myeloid Leukaemia. Annals of Oncology, 15(12), 1810-1815.
  • Foster, A., Forrester, K., Gottlieb, D., Barton, G., Romagnoli, J., Bradstock, K. (2004). Large-Scale Expansion Of Cytomegalovirus-Specific Cytotoxic T Cells In Suspension Culture. Biotechnology and Bioengineering, 85(2), 138-146. [More Information]
  • Antonenas, V., Shaw, P., Bradstock, K. (2004). Letter: Infusion of unwashed umbilical cord blood stem cells after thawing for allogeneic transplantation. Bone Marrow Transplantation, 34(8), 739.
  • Szer, J., Durrant, S., Schwarer, A., Bradstock, K., Gibson, J., Arthur, C., To, L., Hughes, T., Raunow, H. (2004). Oral Versus Intravenous Ganciclovir For The Prophylaxis Of Cytomegalovirus Disease After Allogeneic Bone Marrow Transplantation. Internal Medicine Journal, 34(3), 98-101.
  • Thomas, X., Boiron, J., Huguet, F., Dombret, H., Bradstock, K., Vey, N., Kovacsovics, T., Delannoy, A., Fegueux, N., Fenaux, P., et al (2004). Outcome Of Treatment In Adults With Acute Lymphoblastic Leukemia: Analysis Of The Lala-94 Trial. Journal of Clinical Oncology, 22(20), 4075-4086.
  • Grigg, A., Reynolds, J., McQuillan, A., Juneja, S., Di Iulio, J., Hui, C., Smith, C., Kimber, R., Bradstock, K. (2004). Prognostic features for response and survival in elderly patients with de novo acute myeloid leukemia treated with mitoxantrone and intermediate dose cytarabine. Leukemia and lymphoma, 46(3), 367-375.
  • Branford, S., Rudzki, Z., Parkinson, I., Grigg, A., Taylor, K., Seymour, J., Durrant, S., Browett, P., Schwarer, A., et, A., Bradstock, K. (2004). Real-Time Quantitative Pcr Analysis Can Be Used As A Primary Screen To Identify Patients With Cml Treated With Imatinib Who Have Bcr-Abl Kinase Domain Mutations. Blood, 104(9), 2926-2932.
  • Bendall, L., Nilsson, S., Khan, N., James, A., Bonnet, C., Lock, R., Papa, R., Bradstock, K., Gottlieb, D. (2004). Role of CD44 variant exon 6 in acute lymphoblastic leukaemia: association with altered bone marrow localisation and increased tumor burden. Leukemia, 18(7), 1308-1311.
  • Erdstein, A., Daas, P., Bradstock, K., Robinson, T., Hertzberg, M. (2004). Tuberculosis In Allogeneic Stem Cell Transplant Recipients: Still A Problem In The 21St Century. Transplant Infectious Disease (Print), 6(4), 142-146.
  • Bendall, L., James, A., Zannettino, A., Simmons, P., Gottlieb, D., Bradstock, K. (2003). A novel CD44 antibody identifies an epitope that is aberrantly expressed on acute lymphoblastic leukaemia cells. Immunology and Cell Biology, 81(4), 311-319.
  • Favre, G., Beksac, M., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Szer, J., Bradstock, K., et al (2003). Differences between graft product and donor side effects following bone marrow or stem cell donation. Bone Marrow Transplantation, 32(9), 873-880.
  • Juarez, J., Gottlieb, D., Bradstock, K., Bendall, L. (2003). Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro. Leukemia, 17(7), 1294-1300.
  • Vuckovic, S., Kim, M., Khalil, D., Turtle, C., Crosbie, G., Williams, N., Brown, L., Williams, K., Kelly, C., Stravos, P., Bradstock, K., et al (2003). Granulocyte-colony stimulating factor increases CD123hi blood dendritic cells with altered CD62L and CCR7 expression. Blood, 101(6), 2314-2317.
  • Branford, S., Rudzki, Z., Harper, A., Grigg, A., Taylor, K., Durrant, S., Arthur, C., Browett, P., Schwarer, A., Ma, D., Bradstock, K., et al (2003). Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly disgnosed chronic myeloid leukemia in chronic phase. Leukemia, 17(12), 2401-2409.
  • Zannettino, A., Roubelakis, M., Welldon, K., Jackson, D., Simmons, P., Bendall, L., Henniker, A., Harrison, K., Niutta, S., Bradstock, K., et al (2003). Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. Biochemical Journal, 370(2), 537-549.
  • Hertzberg, M., Crombie, C., Benson, W., Taper, J., Gottlieb, D., Bradstock, K. (2003). Outpatient-based ifosfamede, carboplatin and etoposide (ICE) chemotherapy in transplant-eligible patients with non-Hodgkin's lymphoma and Hodgkin's disease. Annals of Oncology, 14(Supplement 1), i11-i16.
  • Foster, A., Gottlieb, D., Marangolo, M., Bartlett, A., Li, Y., Barton, G., Romagnoli, J., Bradstock, K. (2003). Rapid, Large-Scale Generation of Highly Pure Cytomegalovirus-Specific Cytotoxic T Cells for Adoptive Immunotherapy. Stem Cells and Development, 12(1), 93-105.
  • Lee, D., Chitturi, S., Kench, J., George, J., Fuller, S., Bradstock, K., Lin, R., Wong, K., Young, N. (2003). Transjugular liver biopsy effecting changes in clinical management. Journal of Medical Imaging and Radiation Oncology, 47(2), 117-120. [More Information]
  • Saad, S., Gottlieb, D., Bradstock, K., Overall, C., Bendall, L. (2002). Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts. Cancer Research, 62, 283-289.
  • Foster, A., Gottlieb, D., Sartor, M., Hertzberg, M., Bradstock, K. (2002). Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation. Biology of Blood and Marrow Transplantation, , 501-511.
  • Hensel, N., Melenhorst, J., Bradstock, K., Schwarer, A., Eniafe, R., Nakamura, R., Barrett, A. (2002). Flow cytometric quantitation and characterization of the T-lymphocyte memory response to CMV in healthy donors. Cytotherapy, 4(1), 29-40.
  • Bosly, A., Keating, M., Stasi, R., Bradstock, K. (2002). Rituximab in B-cell disorders other than non-Hodgkin's lymphoma. Anti-Cancer Drugs, 13(supp 2), s25-s33.
  • Bradstock, K. (2002). The use of hematopoietic growth factors in the treatment of acute leukemia. Current Pharmaceutical Design, 8(5), 343-355.
  • Schmitz, N., Beksac, M., Hasenclever, D., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Gorin, N., Bradstock, K., et al (2002). Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia. Blood, 100(3), 761-767.
  • Nivison-Smith, I., Bradstock, K., Szer, J., Durrant, S., Dodds, A., Hermann, R., Schwarer, A., Gibson, J., To, L., Arthur, C. (2001). Allogeneic haemopoietic cell transplants in Australia, 1996--a multi-centre retrospective comparison of the use of peripheral blood stem cells with bone marrow. Bone Marrow Transplantation, 28(1), 21-27.
  • Bradstock, K., Matthews, J., Young, G., Lowenthal, R., Baxter, H., Arthur, C., Bashford, J., Enno, A., Brighton, T., Cannell, P., Gottlieb, D., Joshua, D., et al (2001). Effects of glycosylated recombinant human granulocyte colony-stimulating factor after high-dose cytarabine-based induction chemotherapy for adult acute myeloid leukaemia. Leukemia, 15(9), 1331-1338.
  • Matthews, J., Bishop, J., Young, G., Juneja, S., Lowenthal, R., Garson, O., Cobcroft, R., Dodds, A., Enno, A., Gillett, E., Bradstock, K., et al (2001). Patterns of failure with increasing intensification of induction chemotherapy for acute myeloid leukaemia. British Journal of Haematology, 113(3), 727-736.
  • Smith, A., Robson, L., St Heaps, L., Sharma, P., Dunlop, L., Bhave, A., Bradstock, K. (2001). Routine fluorescence in situ hybridization with the MLL probe does not reliably detect two separate signals on one chromosome 11 in patients with trisomy 11. Cancer Genetics and Cytogenetics, 129(2), 173-176.
  • Shen, W., Bendall, L., Gottlieb, D., Bradstock, K. (2001). The chemokine receptor CXCR4 enhances integrin mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Experimental Hematology, 29(12), 1439-1447.
  • Bradstock, K. (2001). Wanderings of the bone-marrow stem cell. The Lancet, 358(9275), 5-6.
  • Bradstock, K., Makrynikola, V., Bianchi, A., Shen, W., Hewson, J., Gottlieb, D. (2000). Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers. Leukemia, 14(5), 882-888.
  • Bendall, L., Bradstock, K., Gottlieb, D. (2000). Expression of CD44 variant exons in acute myeloid leukemia is more common and more complex than that observed in normal blood, bone marrow or CD34+ cells. Leukemia, 14(7), 1239-1246.
  • Nakase, K., Bradstock, K., Sartor, M., Gottlieb, D., Byth Wilson, K., Kita, H., Shiku, H., Kamada, N. (2000). Geographic heterogeneity of cellular characteristics of acute myeloid leukemia: a comparative study of Australian and Japanese adult cases. Leukemia, 14(1), 163-168.
  • Saad, S., Bendall, L., James, A., Gottlieb, D., Bradstock, K. (2000). Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts. Breast Cancer Research and Treatment, 63(2), 105-115.

Conferences

  • Pati, N., Garvin, F., Antonenas, V., Kerridge, I., Bradstock, K., Gottlieb, D. (2008). Best Approach for Harvesting Bone Marrow to Maximize TNC and CD34+ Cell Counts. 50th American Society of Hematology Annual Meeting and Exposition ASH 2008, United States: American Society of Hematology.
  • George, B., Kerridge, I., Huang, G., Gottlieb, D., Hertzberg, M., Bradstock, K. (2008). Use of Reduced Intensity Conditioning (RIC) Regimens Are Associated with a Better Outcome with Sibling Donors Transplants in Older Patients (> 50 years) with Acute Myeloid Leukemia (AML). 50th American Society of Hematology Annual Meeting and Exposition ASH 2008, United States: American Society of Hematology.
  • Sartor, M., Antonenas, V., Bradstock, K., Gottlieb, D. (2006). Absolute number of transplanted CD34(+) cells expressing C-MPL (CD110) correlates with speed of platelet engraftment following autologous stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Antonenas, V., Bradstock, K., Shaw, P., Gottlieb, D. (2006). Comparison between TNC and CD34+cell counts reported pre-cryopreservation of unrelated cord blood (UCB) units and those observed at the time of their transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Bradstock, K., Lau, J., Sartor, M., Vuckovic, S., Munster, D., Hart, D. (2006). Detection of activated circulating CD11c(+) dendritic cells using CMRF44 antibody is closely associated with the severity of acute gvhd after allogeneic hemopoietic stem cell transplant. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Hansen, A., Micklethwaite, K., Foster, A., Bradstock, K., Gottlieb, D. (2006). Ex vivo expansion of clinical grade CMV specific CTL for therapeutic use in allogeneic haemopoietic stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Antonenas, V., Garvin, F., Sartor, M., Bradstock, K., Gottlieb, D. (2006). Optimum temperature for maintaining the viability of CD34+cells during storage and transport of fresh haematopoietic progenitor cells. 32nd Annual Meeting of the American Society for Blood and Marrow Transplantation, United States: Elsevier Ltd.
  • Juarez, J., Hewson, J., Cisterne, A., Baraz, R., Bradstock, K., Bendall, L. (2005). CXCR4 antagonists mobilize acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment in mice. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Gottlieb, D., Hansen, A., Micklethwaite, K., Foster, A., Turtle, C., Antonenas, V., Sartor, M., Bradstock, K. (2005). Ex-vivo expansion and prophylactic infusion of CMV pp65 specific CTL following haemopoietic stem cell transplantation (HSCT). 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Antonenas, V., Garvin, F., Webb, M., Sartor, M., Bradstock, K., Gottlieb, D. (2005). Optimum temperature for maintaining the viability or CD34+cells during storage and transport of fresh hemopoietic progenitor cells. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Antonenas, V., Garvin, F., Webb, M., Bradstock, K. (2005). Optimum temperature for the storage and transport of fresh haemopoetic progenitor cells. 31st Annual Meeting of the European Group for Blood and Marrow Transplantation (EMBT), London: Nature Publishing Group.
  • Khan, N., Bradstock, K., Bendall, L. (2005). The Wnt/beta-catenin pathway promotes growth and survival of acute lymphoblastic leukaemia (ALL) cells in vitro. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Antonenas, V., Kerridge, I., Thomson, A., Trickett, A., Shaw, P., Bradstock, K. (2004). Development of a policy for the storage and disposal of cryopreserved haematopoietic progenitor cells for the NSW BMT Network Laboratories. Australian and New Zealand Transplant Society.
  • Bradstock, K., Gottlieb, D., Hertzberg, M., Kerridge, I. (2004). Unrelated cord blood transplantation for haematological malignancies in adults: results from Westmead BMT Service. Haematology Society Association of Australia, Annual Scientific Meeting, Melbourne, Victoria.

2014

  • Gasiorowski, R., Clark, G., Bradstock, K., Hart, D. (2014). Antibody therapy for acute myeloid leukaemia. British Journal of Haematology, 164(4), 481-495. [More Information]
  • Raj, K., Pagliuca, A., Bradstock, K., Noriega, V., Potter, V., Streetly, M., McLornan, D., Kazmi, M., Marsh, J., Kwan, J., et al (2014). Peripheral Blood Hematopoietic Stem Cells for Transplantation of Hematological Diseases from Related, Haploidentical Donors after Reduced-Intensity Conditioning. Biology of Blood and Marrow Transplantation, 20(6), 890-895. [More Information]

2013

  • Nivison-Smith, I., Simpson, J., Dodds, A., Ma, D., Szer, J., Bradstock, K. (2013). A population-based analysis of the effect of autologous hematopoietic cell transplant in the treatment of multiple myeloma. Leukemia and Lymphoma, 54(8), 1671-1676. [More Information]
  • Shahin, K., Sartor, M., Hart, D., Bradstock, K. (2013). Alterations in Chemokine Receptor CCR5 Expression on Blood Dendritic Cells Correlate With Acute Graft-Versus-Host Disease. Transplantation, 96(8), 753-762. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Milliken, S., Bardy, P., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Moore, J., et al (2013). Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial. Lancet Infectious Diseases, 13(6), 519-528. [More Information]
  • Bilmon, I., Kwan, J., Gottlieb, D., Kerridge, I., McGurgan, M., Huang, G., George, B., Hertzberg, M., Bradstock, K. (2013). Haploidentical bone marrow transplants for hematological malignancies using non-myeloablative conditioning therapy and post-transplant immunosuppression with cyclophosphamide: results from a single Australian centre. Internal Medicine Journal, 43(2), 191-196. [More Information]
  • Wallington-Beddoe, C., Bradstock, K., Bendall, L. (2013). Oncogenic properties of sphingosine kinases in haematological malignancies. British Journal of Haematology, 161(5), 623-638. [More Information]
  • Welschinger, R., Liedtke, F., Basnett, J., Dela Pena, A., Juarez, J., Bradstock, K., Bendall, L. (2013). Plerixafor (AMD3100) induces prolonged mobilization of acute lymphoblastic leukemia cells and increases the proportion of cycling cells in the blood in mice. Experimental Hematology, 41(3), 293-302.e1. [More Information]
  • Heatley, S., Pietra, G., Lin, J., Widjaja, J., Harpur, C., Lester, S., Rossjohn, J., Szer, J., Schwarer, A., Bradstock, K., et al (2013). Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells. The Journal of Biological Chemistry, 288(12), 8679-8690. [More Information]
  • Saunders, P., Weiss, J., Welschinger, R., Baraz, R., Bradstock, K., Bendall, L. (2013). RAD001 (everolimus) induces dose-dependent changes to cell cycle regulation and modifies the cell cycle response to vincristine. Oncogene, 32(40), 4789-4797. [More Information]

2012

  • George, B., Kerridge, I., Gilroy, N., Huang, G., Hertzberg, M., Bradstock, K., Gottlieb, D. (2012). A risk score for early cytomegalovirus reactivation after allogeneic stem cell transplantation identifies low-, intermediate-, and high-risk groups: reactivation risk is increased by graft-versus-host disease only in the intermediate-risk group. Transplant Infectious Disease (Print), 14(2), 141-148. [More Information]
  • Iland, H., Bradstock, K., Supple, S., Catalano, A., Collins, M., Hertzberg, M., Browett, P., Grigg, A., Firkin, F., Hugman, A., et al (2012). All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4). Blood, 120(8), 1570-1580. [More Information]
  • Nivison-Smith, I., Dodds, A., Butler, J., Bradstock, K., Ma, D., Simpson, J., Szer, J. (2012). Allogeneic Hematopoietic Cell Transplantation for Chronic Myelofibrosis in Australia and New Zealand: Older Recipients Receiving Myeloablative Conditioning at Increased Mortality Risk. Biology of Blood and Marrow Transplantation, 18(2), 302-308. [More Information]
  • Harun, N., Bradstock, K., Bendall, L. (2012). Combination Strategies for Stem Cell Mobilization Targeting CXCR4 and S1P Receptors. In Stefan Fruehauf, W. Jens Zeller and Gary Calandra (Eds.), Novel Developments in Stem Cell Mobilization, (pp. 37-54). New York: Springer Science + Business Media.
  • Wallington-Beddoe, C., Don, A., Hewson, J., Qiao, Q., Papa, R., Lock, R., Bradstock, K., Bendall, L. (2012). Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia. PLoS One, 7(5), 1-7. [More Information]
  • Khan, N., Cisterne, A., Baraz, R., Bradstock, K., Bendall, L. (2012). Para-NO-aspirin inhibits NF-kB and induces apoptosis in B-cell progenitor acute lymphoblastic leukemia. Experimental Hematology, 40(3), 207-215.e1. [More Information]
  • Iland, H., Bradstock, K., Seymour, J., Hertzberg, M., Grigg, A., Taylor, K., Catalano, J., Cannell, P., Horvath, N., Deveridge, S., et al (2012). Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia. Haematologica: the hematology journal, 97(2), 227-234. [More Information]
  • van der Jagt, A., Muirhead, J., Seymour, J., Bradstock, K., Paul, E., Wei, A. (2012). Risk factors for early death after high-dose cytosine arabinoside (HiDAC)-based chemotherapy for adult AML. Leukemia, 26(2), 362-365. [More Information]
  • Juarez, J., Harun, N., Thien, M., Welschinger, R., Baraz, R., Dela Pena, A., Pitson, S., Rettig, M., DiPersio, J., Bradstock, K., Bendall, L. (2012). Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice. Blood, 119(3), 707-716. [More Information]

2011

  • Nivison-Smith, I., Dodds, A., Doocey, R., Ganly, P., Gibson, J., Ma, D., Simpson, J., Szer, J., Bradstock, K., Bradstock, K. (2011). Allogeneic hematopoietic cell transplant for multiple myeloma using reduced intensity conditioning therapy, 1998-2006: factors associated with improved survival outcome. Leukemia and Lymphoma, 52(9), 1727-1735. [More Information]
  • Fromm, P., Gottlieb, D., Bradstock, K., Hart, D. (2011). Cellular therapy to treat haematological and other malignancies: progress and pitfalls. Pathology, 43(6), 605-615. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Schwarer, A., Slavin, M. (2011). Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies. Leukemia and Lymphoma, 52(2), 179-193. [More Information]
  • Wallington-Beddoe, C., Hewson, J., Bradstock, K., Bendall, L. (2011). FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells. Autophagy, 7(7), 707-715. [More Information]
  • Nivison-Smith, I., Dodds, A., Dunckley, H., Ma, D., Moore, J., Simpson, J., Szer, J., Bradstock, K. (2011). Increased activity and improved outcome in unrelated donor haemopoietic cell transplants for acute myeloid leukaemia in Australia, 1992-2005. Internal Medicine Journal, 41(1A), 27-34. [More Information]
  • Bray, L., Jordens, C., Rowlings, P., Bradstock, K., Kerridge, I. (2011). The long haul: Caring for bone marrow transplant patients in regional Australia. Australian Journal of Advanced Nursing, 29(1), 5-13.
  • Saunders, P., Cisterne, A., Weiss, J., Bradstock, K., Bendall, L. (2011). The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia. Haematologica: the hematology journal, 96(1), 69-77. [More Information]

2010

  • Murray, P., Kerridge, I., Tiley, C., Catanzariti, A., Welberry, H., Lean, C., Sinclair, S., Bishop, J., Bradstock, K. (2010). Enrolment of patients to clinical trials in haematological cancer in New South Wales: Current status, perceived barriers and opportunities for improvement. Internal Medicine Journal, 40(2), 133-138. [More Information]
  • George, B., Kerridge, I., Gilroy, N., Huang, G., Hertzberg, M., Gottlieb, D., Bradstock, K. (2010). Fludarabine-based reduced intensity conditioning transplants have a higher incidence of cytomegalovirus reactivation compared with myeloablative transplants. Bone Marrow Transplantation, 45(5), 849-855. [More Information]
  • George, B., Pati, N., Gilroy, N., Ratnamohan, M., Huang, G., Kerridge, I., Hertzberg, M., Gottlieb, D., Bradstock, K. (2010). Pre-transplant cytomegalovirus (CMV) serostatus remains the most important determinant of CMV reactivation after allogeneic hematopoietic stem cell transplantation in the era of surveillance and preemptive therapy. Transplant Infectious Disease (Print), 12(4), 322-329. [More Information]

2009

  • Spencer, A., Prince, H., Roberts, A., Prosser, I., Bradstock, K., Coyle, L., Gill, D., Horvath, N., Reynolds, J., Kennedy, N. (2009). Consolidation Therapy With Low-Dose Thalidomide and Prednisolone Prolongs the Survival of Multiple Myeloma Patients Undergoing a Single Autologous Stem-Cell Transplantation Procedure. Journal of Clinical Oncology, 27(11), 1788-1793. [More Information]
  • Juarez, J., Thien, M., Dela Pena, A., Baraz, R., Bradstock, K., Bendall, L. (2009). CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK. British Journal of Haematology, 145, 491-499. [More Information]
  • Brooke, G., Rossetti, T., Pelekanos, R., Ilic, N., Murray, P., Hancock, S., Antonenas, V., Huang, G., Gottlieb, D., Bradstock, K., et al (2009). Manufacturing of human placenta-derived mesenchymal stem cells for clinical trials. British Journal of Haematology, 144(4), 571-579. [More Information]
  • Deo, S., Bradstock, K., Bendall, L. (2009). p38MAPK inhibitors attenuate cytokine production by bone marrow stromal cells and reduce stroma-mediated proliferation of acute lymphoblastic leukemia cells. Cell Cycle, 8(18), 2977-2985. [More Information]
  • Ferguson, P., Sorrell, T., Bradstock, K., Carr, P., Gilroy, N. (2009). Parainfluenza Virus Type 3 Pneumonia in Bone Marrow Transplant Recipients: Multiple Small Nodules in High-Resolution Lung Computed Tomography Scans Provide a Radiological Clue to Diagnosis. Clinical Infectious Diseases, 48(7), 905-909. [More Information]
  • Crazzolara, R., Cisterne, A., Thien, M., Hewson, J., Baraz, R., Bradstock, K., Bendall, L. (2009). Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia. Blood, 113(14), 3297-3306. [More Information]
  • Crazzolara, R., Bradstock, K., Bendall, L. (2009). RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia. Autophagy, 5(5), 727-728. [More Information]
  • Nivison-Smith, I., Simpson, J., Dodds, A., Ma, D., Szer, J., Bradstock, K. (2009). Relative Survival of Long-Term Hematopoietic Cell Transplant Recipients Approaches General Population Rates. Biology of Blood and Marrow Transplantation, 15(10), 1323-1330. [More Information]
  • Bradstock, K., Hertzberg, M., Kerridge, I., Svennilson, J., George, B., McGurgan, M., Huang, G., Antonenas, V., Gottlieb, D. (2009). Single versus double unrelated umbilical cord blood units for allogeneic transplantation in adults with advanced hematological malignancies: a retrospective comparison of outcomes. Internal Medicine Journal, 39(11), 744-751. [More Information]

2008

  • George, B., Kerridge, I., Gottlieb, D., Huang, G., Hertzberg, M., Svennilson, J., Bradstock, K. (2008). A reduced intensity conditioning protocol associated with excellent survival in patients with myelofibrosis. Bone Marrow Transplantation, 42(8), 567-568. [More Information]
  • Pati, N., Garvin, F., Antonenas, V., Kerridge, I., Bradstock, K., Gottlieb, D. (2008). Best Approach for Harvesting Bone Marrow to Maximize TNC and CD34+ Cell Counts. 50th American Society of Hematology Annual Meeting and Exposition ASH 2008, United States: American Society of Hematology.
  • Bradstock, K. (2008). Can the influence of karyotype in acute myeloid leukemia be overcome by high-dose chemotherapy? Leukemia and Lymphoma, 49(12), 2227-2228. [More Information]
  • Khan, N., Cisterne, A., Devidas, M., Shuster, J., Hunger, S., Shaw, P., Bradstock, K., Bendall, L. (2008). Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics. Leukemia and lymphoma, 49(4), 710-718. [More Information]
  • Mullighan, C., Heatley, S., Danner, S., Dean, M., Doherty, K., Hahn, U., Bradstock, K., Minchinton, R., Schwarer, A., Szer, J., et al (2008). Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation. Blood, 112(5), 2120-2128.
  • Micklethwaite, K., Clancy, L., Sandher, U., Hansen, A., Blyth, E., Antonenas, V., Sartor, M., Bradstock, K., Gottlieb, D. (2008). Prophylactic infusion of cytomegalovirus specific cytotoxic T-lymphocytes stimulated with Ad5f35pp65 gene modified dendritic cells following allogeneic haemopoietic stem cell transplantation. Blood, 112(10), 3974-3981. [More Information]
  • George, B., Kerridge, I., Huang, G., Gottlieb, D., Hertzberg, M., Bradstock, K. (2008). Use of Reduced Intensity Conditioning (RIC) Regimens Are Associated with a Better Outcome with Sibling Donors Transplants in Older Patients (> 50 years) with Acute Myeloid Leukemia (AML). 50th American Society of Hematology Annual Meeting and Exposition ASH 2008, United States: American Society of Hematology.

2007

  • Grigg, A., Gibson, J., Bardy, P., Reynolds, J., Shuttleworth, P., Koelmeyer, R., Szer, J., Roberts, A., To, L., Kennedy, G., Bradstock, K. (2007). A prospective multicenter trial of peripheral blood stem cell sibling allografts for acute myeloid leukemia in first complete remission using fludarabine-cyclophosphamide reduced intensity conditioning. Biology of Blood and Marrow Transplantation, 13(5), 560-567. [More Information]
  • Lau, J., Sartor, M., Bradstock, K., Vuckovic, S., Munster, D., Hart, D. (2007). Activated circulating dendritic cells after hematopoietic stem cell transplantation predict acute graft-versus-host disease. Transplantation, 83(7), 839-846. [More Information]
  • Khan, N., Bradstock, K., Bendall, L. (2007). Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia. British Journal of Haematology, 138(3), 338-348. [More Information]
  • Juarez, J., Dela Pena, A., Baraz, R., Hewson, J., Khoo, M., Cisterne, A., Fricker, S., Fujii, N., Bradstock, K., Bendall, L. (2007). CXCR4 antagonists mobilize childhood acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment. Leukemia, 21(6), 1249-1257. [More Information]
  • Moore, J., Nivison-Smith, I., Goh, K., Ma, D., Bradstock, K., Szer, J., Durrant, S., Schwarer, A., Bardy, P., Herrmann, R., et al (2007). Equivalent survival for sibling and unrelated donor allogeneic stem cell transplantation for acute myelogenous leukemia. Biology of Blood and Marrow Transplantation, 13(5), 601-607. [More Information]
  • Micklethwaite, K., Hansen, A., Foster, A., Snape, E., Antonenas, V., Sartor, M., Shaw, P., Bradstock, K., Gottlieb, D. (2007). Ex vivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation, 13(6), 707-714. [More Information]
  • Sartor, M., Garvin, F., Antonenas, V., Bradstock, K., Gottlieb, D. (2007). Failure to achieve a threshold dose of CD34(+)CD110(+) progenitor cells in the graft predicts delayed platelet engraftment after autologous stem cell transplantation. Bone Marrow Transplantation, 40(9), 851-857. [More Information]
  • Nivison-Smith, I., Bradstock, K., Dodds, A., Hawkins, P., Ma, D., Moore, J., Simpson, J., Szer, J. (2007). Hematopoietic stem cell transplantation in Australia and New Zealand, 1992-2004. Biology of Blood and Marrow Transplantation, 13(8), 905-912. [More Information]
  • Juarez, J., Baraz, R., Deo, S., Bradstock, K., Bendall, L. (2007). Interaction of interleukin-7 and interleukin-3 with the CXCL12-induced proliferation of B-cell progenitor acute lymphoblastic leukemia. Haematologica: the hematology journal, 92(4), 450-459. [More Information]
  • Tavernier, E., Boiron, J., Huguet, F., Bradstock, K., Vey, N., Kovacsovics, T., Delannoy, A., Fegueux, N., Fenaux, P., Stamatoullas, A., et al (2007). Outcome of treatment after first relapse in adults with acute lymphoblastic leukemia initially treated by the LALA-94 trial. Leukemia, 21(9), 1907-1914. [More Information]
  • Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy, 9(2), 133-143. [More Information]
  • Feyler, S., Prince, H., Pearce, R., Towlson, K., Nivison-Smith, I., Schey, S., Gibson, J., Patton, N., Bradstock, K., Marks, D., et al (2007). The role of high-dose therapy and stem cell rescue in the management of T-cell malignant lymphomas: a BSBMT and ABMTRR study. Bone Marrow Transplantation, 40(5), 443-450. [More Information]

2006

  • Sartor, M., Antonenas, V., Bradstock, K., Gottlieb, D. (2006). Absolute number of transplanted CD34(+) cells expressing C-MPL (CD110) correlates with speed of platelet engraftment following autologous stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Hill, G., Morris, E., Fuery, M., Hutchins, C., Butler, J., Grigg, A., Roberts, A., Bradstock, K., Szer, J., Kennedy, G., et al (2006). Allogeneic stem cell transplantation with peripheral blood stem cells mobilized by pegylated G-CSF. Biology of Blood and Marrow Transplantation, 12(6), 603-607. [More Information]
  • Belov, L., Mulligan, S., Barber, N., Woolfson, A., Scott, M., Stoner, K., Chrisp, J., Sewell, W., Bradstock, K., Bendall, L., Sartor, M., Young, G., Wiley, J., Christopherson, R., et al (2006). Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray. British Journal of Haematology, 135(2), 184-97. [More Information]
  • Dhedin, N., Dombret, H., Thomas, X., Lheritier, V., Boiron, J., Rigal-Huguet, F., Vernant, J., Kuentz, M., Reman, O., Bradstock, K., et al (2006). Autologous stem cell transplantation in adults with acute lymphoblastic leukemia in first complete remission: analysis of the LALA-85,-87 and-94 trials. Leukemia, 20(2), 336-344.
  • Bradstock, K. (2006). Chemotherapy for patients with acute myeloid leukemia in first remission. Current Hematologic Malignancy Reports, 1(2), 108-113. [More Information]
  • Antonenas, V., Bradstock, K., Shaw, P., Gottlieb, D. (2006). Comparison between TNC and CD34+cell counts reported pre-cryopreservation of unrelated cord blood (UCB) units and those observed at the time of their transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Bradstock, K., Lau, J., Sartor, M., Vuckovic, S., Munster, D., Hart, D. (2006). Detection of activated circulating CD11c(+) dendritic cells using CMRF44 antibody is closely associated with the severity of acute gvhd after allogeneic hemopoietic stem cell transplant. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Hansen, A., Micklethwaite, K., Foster, A., Bradstock, K., Gottlieb, D. (2006). Ex vivo expansion of clinical grade CMV specific CTL for therapeutic use in allogeneic haemopoietic stem cell transplantation. 2nd International Conference 'Strategies in Tissue Engineering', United Kingdom: Informa Healthcare.
  • Lau, J., Sartor, M., Vuckovic, S., Munster, D., Bradstock, K., Hart, D. (2006). Expression of activation marker, CMRF-44, on blood CD11c(hi) dendritic cells is closely associated with the severity of acute gvhd after allogeneic haematopoietic stem cell transplant. Immunology and Cell Biology, 84(3), A9-A9.
  • Antonenas, V., Garvin, F., Webb, M., Sartor, M., Bradstock, K., Gottlieb, D. (2006). Fresh PBSC harvests, but not BM, show temperature-related loss of CD34 viability during storage and transport. Cytotherapy, 8(2), 158-165. [More Information]
  • Gottlieb, D., Li, Y., Lionello, I., Tanzarella, S., Marangolo, M., Bradstock, K., Russo, V., Traversari, C. (2006). Generation of tumour-specific cytotoxic T-cell clones from histocompatibility leucocyte antigen-identical siblings of patients with melanoma. British Journal of Cancer, 95(2), 181-188. [More Information]
  • Antonenas, V., Garvin, F., Sartor, M., Bradstock, K., Gottlieb, D. (2006). Optimum temperature for maintaining the viability of CD34+cells during storage and transport of fresh haematopoietic progenitor cells. 32nd Annual Meeting of the American Society for Blood and Marrow Transplantation, United States: Elsevier Ltd.
  • Hertzberg, M., Crombie, C., Benson, W., Taper, J., Gottlieb, D., Bradstock, K. (2006). Outpatient fractionated ifosfamide, carboplatin and etoposide as salvage therapy in relapsed and refractory non-Hodgkin's and Hodgkin's lymphoma. Annals of Oncology, 17 Suppl 4, iv25-iv30. [More Information]
  • Grigg, A., Shuttleworth, P., Reynolds, J., Schwarer, A., Szer, J., Bradstock, K., Hui, C., Herrmann, R., Ebeling, P. (2006). Pamidronate reduces bone loss after allogeneic stem cell transplantation. Journal of Clinical Endocrinology and Metabolism, 91(10), 3835-3843. [More Information]
  • Hertzberg, M., Grigg, A., Gottlieb, D., Szer, J., Roberts, A., Hoyt, R., Huang, G., Bradstock, K. (2006). Reduced-intensity allogeneic haemopoietic stem cell transplantation induces durable responses in patients with chronic B-lymphoproliferative disorders. Bone Marrow Transplantation, 37(10), 923-928. [More Information]
  • Halliday, C., Hoile, R., Sorrell, T., James, G., Yadav, S., Shaw, P., Bleakley, M., Bradstock, K., Chen, S. (2006). Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia. British Journal of Haematology, 132(4), 478-486. [More Information]
  • Crowther, H., Collins, D., Antonenas, V., McGurgan, M., Kerridge, I., Gottlieb, D., Bradstock, K. (2006). Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins. Bone Marrow Transplantation, 37(3), 329-330. [More Information]
  • Crowther, H., Collins, D., Antonenas, V., McGurgan, M., Kerridge, I., Gottlieb, D., Bradstock, K. (2006). Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins. Bone Marrow Transplantation, 37(3), 329-330.
  • Bradstock, K., Hertzberg, M., Kerridge, I., Svennilson, J., McGurgan, M., Huang, G., Antonenas, V., Gottlieb, D. (2006). Unrelated umbilical cord blood transplantation for adults with haematological malignancies: results from a single Australian centre. Internal Medicine Journal, 36(6), 355-361. [More Information]

2005

  • Bradstock, K., Matthews, J., Lowenthal, R., Baxter, H., Catalano, J., Brighton, T., Gill, D., Eliadis, P., Joshua, D., Cannell, P., Koutts, J., Young, G., et al (2005). A randomized trial of high- versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine. Blood, 105(2), 481-488.
  • Sader, M., McGrath, K., Hill, M., Bradstock, K., Jimenez, M., Handelsman, D., Celermajer, D., Heather, A. (2005). Androgen receptor gene expression in leucocytes is hormonally regulated: implications for gender differences in disease pathogenesis. Clinical Endocrinology, 62(1), 56-63. [More Information]
  • Juarez, J., Hewson, J., Cisterne, A., Baraz, R., Bradstock, K., Bendall, L. (2005). CXCR4 antagonists mobilize acute lymphoblastic leukemia cells into the peripheral blood and inhibit engraftment in mice. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Bendall, L., Baraz, R., Juarez, J., Shen, W., Bradstock, K. (2005). Defective p38 mitogen-activated protein kinase signaling impairs chemotaxic but not proliferative responses to stromal-derived factor-1alpha in acute lymphoblastic leukemia. Cancer Research. [More Information]
  • Gottlieb, D., Hansen, A., Micklethwaite, K., Foster, A., Turtle, C., Antonenas, V., Sartor, M., Bradstock, K. (2005). Ex-vivo expansion and prophylactic infusion of CMV pp65 specific CTL following haemopoietic stem cell transplantation (HSCT). 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Schmitz, N., Beksac, M., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Szer, J., Bradstock, K., et al (2005). Filgrastim-mobilized peripheral blood progenitor cells versus bone marrow transplantation for treating leukemia: 3-year results from the EBMT randomized trial. Haematologica: the hematology journal, 90(5), 643-648. [More Information]
  • Campana, D., Iwamoto, D., Bendall, L., Bradstock, K. (2005). Growth requirements and immunophenotype of acute lymphoblastic leukemia progenitors. Blood, 105(10), 4150. [More Information]
  • Nivison-Smith, I., Bradstock, K., Dodds, A., Hawkins, P., Szer, J. (2005). Haemopoietic stem cell transplantation in Australia and New Zealand, 1992-2001: progress report from the Australasian Bone Marrow Transplant Recipient Registry. Internal Medicine Journal, 35(1), 18-27. [More Information]
  • Favaloro, E., Bonar, R., Kershaw, G., Sioufi, J., Thom, J., Baker, R., Hertzberg, M., Street, A., Lloyd, J., Marsden, K., Hewson, J., Bradstock, K., Sartor, M., Wong, S., Fulcher, D., et al (2005). Laboratory diagnosis of von Willebrand disorder: use of multiple functional assays reduces diagnostic error rates. Laboratory Hematology, 11(2), 91-97. [More Information]
  • Bradstock, K. (2005). Lymphoma: the good, the bad and the ugly. Medicine Today, 6(9), 25-33.
  • Bendall, L., Bradstock, K. (2005). New therapies targeting chemokine receptors: Can changing the way cells traffic be used to treat human disease? Current Topics in Membranes, 55, 331-365.
  • Barton, G., Forrester, K., Bradstock, K., Gottlieb, D., Foster, A. (2005). Optimizing bioreactor productivity for therapeutic immune cells. Food and Bioproducts Processing, 83(C2), 158-163.
  • Antonenas, V., Garvin, F., Webb, M., Sartor, M., Bradstock, K., Gottlieb, D. (2005). Optimum temperature for maintaining the viability or CD34+cells during storage and transport of fresh hemopoietic progenitor cells. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.
  • Antonenas, V., Garvin, F., Webb, M., Bradstock, K. (2005). Optimum temperature for the storage and transport of fresh haemopoetic progenitor cells. 31st Annual Meeting of the European Group for Blood and Marrow Transplantation (EMBT), London: Nature Publishing Group.
  • Sartor, M., Antonenas, V., Garvin, F., Webb, M., Bradstock, K. (2005). Recovery of viable CD34þ cells from cryopreserved hemopoietic progenitor cell products. Bone Marrow Transplantation, 36(3), 199-204. [More Information]
  • Khan, N., Bradstock, K., Bendall, L. (2005). The Wnt/beta-catenin pathway promotes growth and survival of acute lymphoblastic leukaemia (ALL) cells in vitro. 47th Annual Meeting of the American Society of Hematology (ASH), United States: American Society of Hematology.

2004

  • Foster, A., Bradstock, K., Sili, U., Marangolo, M., Rooney, C., Gottlieb, D. (2004). A Comparison Of Gene Transfer And Antigen-Loaded Dendritic Cells For The Generation Of Cd4+ And Cd8+ Cytomegalovirus-Specific T Cells In Hla-A2+ And Hla-A2- Donors. Biology of Blood and Marrow Transplantation, 10(11), 761-771. [More Information]
  • Bradstock, K. (2004). Adult leukaemias: prognostic classification and treatment. Medicine Today, 5(5), 41-47.
  • Juarez, J., Bendall, L., Bradstock, K. (2004). Chemokines And Their Receptors As Therapeutic Targets: The Role Of The Sdf-1/Cxcr4 Axis. Current Pharmaceutical Design, 10(11), 1245-1259.
  • Antonenas, V., Kerridge, I., Thomson, A., Trickett, A., Shaw, P., Bradstock, K. (2004). Development of a policy for the storage and disposal of cryopreserved haematopoietic progenitor cells for the NSW BMT Network Laboratories. Australian and New Zealand Transplant Society.
  • McGowan, E., Saad, S., Bendall, L., Bradstock, K., Clarke, C. (2004). Effect Of Progesterone Receptor A Predominance On Breast Cancer Cell Migration Into Bone Marrow Fibroblasts. Breast Cancer Research and Treatment, 83(3), 211-220.
  • Foster, A., Marangolo, M., Sartor, M., Alexander, S., Hu, M., Bradstock, K., Gottlieb, D. (2004). Human Cd62L- Memory T Cells Are Less Responsive To Alloantigen Stimulation Than Cd62L+ Naive T Cells: Potential For Adoptive Immunotherapy And Allodepletion. Blood, 104(8), 2403-2409.
  • Mollee, P., Arthur, C., Hughes, T., Januszewicz, H., Grigg, A., Bradstock, K., Wolf, M., Gibson, J., Schwarer, A., Spencer, A., et al (2004). Interferon-Alpha-2B And Oral Cytarabine Ocfosfate For Newly Diagnosed Chronic Myeloid Leukaemia. Annals of Oncology, 15(12), 1810-1815.
  • Foster, A., Forrester, K., Gottlieb, D., Barton, G., Romagnoli, J., Bradstock, K. (2004). Large-Scale Expansion Of Cytomegalovirus-Specific Cytotoxic T Cells In Suspension Culture. Biotechnology and Bioengineering, 85(2), 138-146. [More Information]
  • Antonenas, V., Shaw, P., Bradstock, K. (2004). Letter: Infusion of unwashed umbilical cord blood stem cells after thawing for allogeneic transplantation. Bone Marrow Transplantation, 34(8), 739.
  • Szer, J., Durrant, S., Schwarer, A., Bradstock, K., Gibson, J., Arthur, C., To, L., Hughes, T., Raunow, H. (2004). Oral Versus Intravenous Ganciclovir For The Prophylaxis Of Cytomegalovirus Disease After Allogeneic Bone Marrow Transplantation. Internal Medicine Journal, 34(3), 98-101.
  • Thomas, X., Boiron, J., Huguet, F., Dombret, H., Bradstock, K., Vey, N., Kovacsovics, T., Delannoy, A., Fegueux, N., Fenaux, P., et al (2004). Outcome Of Treatment In Adults With Acute Lymphoblastic Leukemia: Analysis Of The Lala-94 Trial. Journal of Clinical Oncology, 22(20), 4075-4086.
  • Grigg, A., Reynolds, J., McQuillan, A., Juneja, S., Di Iulio, J., Hui, C., Smith, C., Kimber, R., Bradstock, K. (2004). Prognostic features for response and survival in elderly patients with de novo acute myeloid leukemia treated with mitoxantrone and intermediate dose cytarabine. Leukemia and lymphoma, 46(3), 367-375.
  • Branford, S., Rudzki, Z., Parkinson, I., Grigg, A., Taylor, K., Seymour, J., Durrant, S., Browett, P., Schwarer, A., et, A., Bradstock, K. (2004). Real-Time Quantitative Pcr Analysis Can Be Used As A Primary Screen To Identify Patients With Cml Treated With Imatinib Who Have Bcr-Abl Kinase Domain Mutations. Blood, 104(9), 2926-2932.
  • Bendall, L., Nilsson, S., Khan, N., James, A., Bonnet, C., Lock, R., Papa, R., Bradstock, K., Gottlieb, D. (2004). Role of CD44 variant exon 6 in acute lymphoblastic leukaemia: association with altered bone marrow localisation and increased tumor burden. Leukemia, 18(7), 1308-1311.
  • Erdstein, A., Daas, P., Bradstock, K., Robinson, T., Hertzberg, M. (2004). Tuberculosis In Allogeneic Stem Cell Transplant Recipients: Still A Problem In The 21St Century. Transplant Infectious Disease (Print), 6(4), 142-146.
  • Bradstock, K., Gottlieb, D., Hertzberg, M., Kerridge, I. (2004). Unrelated cord blood transplantation for haematological malignancies in adults: results from Westmead BMT Service. Haematology Society Association of Australia, Annual Scientific Meeting, Melbourne, Victoria.

2003

  • Bendall, L., James, A., Zannettino, A., Simmons, P., Gottlieb, D., Bradstock, K. (2003). A novel CD44 antibody identifies an epitope that is aberrantly expressed on acute lymphoblastic leukaemia cells. Immunology and Cell Biology, 81(4), 311-319.
  • Favre, G., Beksac, M., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Szer, J., Bradstock, K., et al (2003). Differences between graft product and donor side effects following bone marrow or stem cell donation. Bone Marrow Transplantation, 32(9), 873-880.
  • Juarez, J., Gottlieb, D., Bradstock, K., Bendall, L. (2003). Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro. Leukemia, 17(7), 1294-1300.
  • Vuckovic, S., Kim, M., Khalil, D., Turtle, C., Crosbie, G., Williams, N., Brown, L., Williams, K., Kelly, C., Stravos, P., Bradstock, K., et al (2003). Granulocyte-colony stimulating factor increases CD123hi blood dendritic cells with altered CD62L and CCR7 expression. Blood, 101(6), 2314-2317.
  • Branford, S., Rudzki, Z., Harper, A., Grigg, A., Taylor, K., Durrant, S., Arthur, C., Browett, P., Schwarer, A., Ma, D., Bradstock, K., et al (2003). Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly disgnosed chronic myeloid leukemia in chronic phase. Leukemia, 17(12), 2401-2409.
  • Zannettino, A., Roubelakis, M., Welldon, K., Jackson, D., Simmons, P., Bendall, L., Henniker, A., Harrison, K., Niutta, S., Bradstock, K., et al (2003). Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration. Biochemical Journal, 370(2), 537-549.
  • Hertzberg, M., Crombie, C., Benson, W., Taper, J., Gottlieb, D., Bradstock, K. (2003). Outpatient-based ifosfamede, carboplatin and etoposide (ICE) chemotherapy in transplant-eligible patients with non-Hodgkin's lymphoma and Hodgkin's disease. Annals of Oncology, 14(Supplement 1), i11-i16.
  • Foster, A., Gottlieb, D., Marangolo, M., Bartlett, A., Li, Y., Barton, G., Romagnoli, J., Bradstock, K. (2003). Rapid, Large-Scale Generation of Highly Pure Cytomegalovirus-Specific Cytotoxic T Cells for Adoptive Immunotherapy. Stem Cells and Development, 12(1), 93-105.
  • Lee, D., Chitturi, S., Kench, J., George, J., Fuller, S., Bradstock, K., Lin, R., Wong, K., Young, N. (2003). Transjugular liver biopsy effecting changes in clinical management. Journal of Medical Imaging and Radiation Oncology, 47(2), 117-120. [More Information]

2002

  • Saad, S., Gottlieb, D., Bradstock, K., Overall, C., Bendall, L. (2002). Cancer cell-associated fibronectin induces release of matrix metalloproteinase-2 from normal fibroblasts. Cancer Research, 62, 283-289.
  • Foster, A., Gottlieb, D., Sartor, M., Hertzberg, M., Bradstock, K. (2002). Cytomegalovirus-specific CD4+ and CD8+ T-cells follow a similar reconstitution pattern after allogeneic stem cell transplantation. Biology of Blood and Marrow Transplantation, , 501-511.
  • Hensel, N., Melenhorst, J., Bradstock, K., Schwarer, A., Eniafe, R., Nakamura, R., Barrett, A. (2002). Flow cytometric quantitation and characterization of the T-lymphocyte memory response to CMV in healthy donors. Cytotherapy, 4(1), 29-40.
  • Bosly, A., Keating, M., Stasi, R., Bradstock, K. (2002). Rituximab in B-cell disorders other than non-Hodgkin's lymphoma. Anti-Cancer Drugs, 13(supp 2), s25-s33.
  • Bradstock, K. (2002). The use of hematopoietic growth factors in the treatment of acute leukemia. Current Pharmaceutical Design, 8(5), 343-355.
  • Schmitz, N., Beksac, M., Hasenclever, D., Bacigalupo, A., Ruutu, T., Nagler, A., Gluckman, E., Russell, N., Apperley, J., Gorin, N., Bradstock, K., et al (2002). Transplantation of mobilized peripheral blood cells to HLA-identical siblings with standard-risk leukemia. Blood, 100(3), 761-767.

2001

  • Nivison-Smith, I., Bradstock, K., Szer, J., Durrant, S., Dodds, A., Hermann, R., Schwarer, A., Gibson, J., To, L., Arthur, C. (2001). Allogeneic haemopoietic cell transplants in Australia, 1996--a multi-centre retrospective comparison of the use of peripheral blood stem cells with bone marrow. Bone Marrow Transplantation, 28(1), 21-27.
  • Bradstock, K., Matthews, J., Young, G., Lowenthal, R., Baxter, H., Arthur, C., Bashford, J., Enno, A., Brighton, T., Cannell, P., Gottlieb, D., Joshua, D., et al (2001). Effects of glycosylated recombinant human granulocyte colony-stimulating factor after high-dose cytarabine-based induction chemotherapy for adult acute myeloid leukaemia. Leukemia, 15(9), 1331-1338.
  • Matthews, J., Bishop, J., Young, G., Juneja, S., Lowenthal, R., Garson, O., Cobcroft, R., Dodds, A., Enno, A., Gillett, E., Bradstock, K., et al (2001). Patterns of failure with increasing intensification of induction chemotherapy for acute myeloid leukaemia. British Journal of Haematology, 113(3), 727-736.
  • Smith, A., Robson, L., St Heaps, L., Sharma, P., Dunlop, L., Bhave, A., Bradstock, K. (2001). Routine fluorescence in situ hybridization with the MLL probe does not reliably detect two separate signals on one chromosome 11 in patients with trisomy 11. Cancer Genetics and Cytogenetics, 129(2), 173-176.
  • Shen, W., Bendall, L., Gottlieb, D., Bradstock, K. (2001). The chemokine receptor CXCR4 enhances integrin mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Experimental Hematology, 29(12), 1439-1447.
  • Bradstock, K. (2001). Wanderings of the bone-marrow stem cell. The Lancet, 358(9275), 5-6.

2000

  • Bradstock, K., Makrynikola, V., Bianchi, A., Shen, W., Hewson, J., Gottlieb, D. (2000). Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers. Leukemia, 14(5), 882-888.
  • Bendall, L., Bradstock, K., Gottlieb, D. (2000). Expression of CD44 variant exons in acute myeloid leukemia is more common and more complex than that observed in normal blood, bone marrow or CD34+ cells. Leukemia, 14(7), 1239-1246.
  • Nakase, K., Bradstock, K., Sartor, M., Gottlieb, D., Byth Wilson, K., Kita, H., Shiku, H., Kamada, N. (2000). Geographic heterogeneity of cellular characteristics of acute myeloid leukemia: a comparative study of Australian and Japanese adult cases. Leukemia, 14(1), 163-168.
  • Saad, S., Bendall, L., James, A., Gottlieb, D., Bradstock, K. (2000). Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts. Breast Cancer Research and Treatment, 63(2), 105-115.

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